LOCUS       DAVLCS010000001       126484 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLCS010000001 DAVLCS010000000
VERSION     DAVLCS010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 126484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 126484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..126484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.001"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(<1..218)
                     /locus_tag="VXC78_000001"
     CDS             complement(<1..218)
                     /locus_tag="VXC78_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0582167.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIR"
     gene            complement(340..2298)
                     /gene="ftsH"
                     /locus_tag="VXC78_000002"
     CDS             complement(340..2298)
                     /gene="ftsH"
                     /locus_tag="VXC78_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV0582168.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2314..2856)
                     /gene="hpt"
                     /locus_tag="VXC78_000003"
     CDS             complement(2314..2856)
                     /gene="hpt"
                     /locus_tag="VXC78_000003"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV0582169.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2860..4137)
                     /gene="tilS"
                     /locus_tag="VXC78_000004"
     CDS             complement(2860..4137)
                     /gene="tilS"
                     /locus_tag="VXC78_000004"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV0582170.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIINTVLYIEKIDR"
     gene            complement(4134..5402)
                     /locus_tag="VXC78_000005"
     CDS             complement(4134..5402)
                     /locus_tag="VXC78_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV0582171.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFSIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5522..5890)
                     /locus_tag="VXC78_000006"
     CDS             complement(5522..5890)
                     /locus_tag="VXC78_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV0582172.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5883..6149)
                     /locus_tag="VXC78_000007"
     CDS             complement(5883..6149)
                     /locus_tag="VXC78_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV0582173.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6207..9716)
                     /gene="mfd"
                     /locus_tag="VXC78_000008"
     CDS             complement(6207..9716)
                     /gene="mfd"
                     /locus_tag="VXC78_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV0582174.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9717..10286)
                     /locus_tag="VXC78_000009"
     CDS             complement(9717..10286)
                     /locus_tag="VXC78_000009"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV0582175.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            complement(10358..11473)
                     /gene="ychF"
                     /locus_tag="VXC78_000010"
     CDS             complement(10358..11473)
                     /gene="ychF"
                     /locus_tag="VXC78_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV0582176.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11557..11751)
                     /locus_tag="VXC78_000011"
     CDS             complement(11557..11751)
                     /locus_tag="VXC78_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV0582177.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11816..12952)
                     /gene="dnaN"
                     /locus_tag="VXC78_000012"
     CDS             complement(11816..12952)
                     /gene="dnaN"
                     /locus_tag="VXC78_000012"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV0582178.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(13111..14472)
                     /gene="dnaA"
                     /locus_tag="VXC78_000013"
     CDS             complement(13111..14472)
                     /gene="dnaA"
                     /locus_tag="VXC78_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV0582179.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14685..15443)
                     /locus_tag="VXC78_000014"
     CDS             complement(14685..15443)
                     /locus_tag="VXC78_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV0582180.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15501..16682)
                     /locus_tag="VXC78_000015"
     CDS             complement(15501..16682)
                     /locus_tag="VXC78_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0582181.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16865..17344
                     /gene="rlmH"
                     /locus_tag="VXC78_000016"
     CDS             16865..17344
                     /gene="rlmH"
                     /locus_tag="VXC78_000016"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV0582182.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17388..17461
                     /locus_tag="VXC78_000017"
     tRNA            17388..17461
                     /locus_tag="VXC78_000017"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17422..17424,aa:Arg,seq:tct)
     gene            17627..17752
                     /gene="comC"
                     /locus_tag="VXC78_000018"
     CDS             17627..17752
                     /gene="comC"
                     /locus_tag="VXC78_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV0582183.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17773..19098
                     /locus_tag="VXC78_000019"
     CDS             17773..19098
                     /locus_tag="VXC78_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0582184.1"
                     /translation="MDLFGFGTVIVHLLIISHNYHLICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIAIFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFS
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            19095..19847
                     /locus_tag="VXC78_000020"
     CDS             19095..19847
                     /locus_tag="VXC78_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0582185.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQFIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19899..19970
                     /locus_tag="VXC78_000021"
     tRNA            19899..19970
                     /locus_tag="VXC78_000021"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19932..19934,aa:Glu,seq:ttc)
     gene            19976..20049
                     /locus_tag="VXC78_000022"
     tRNA            19976..20049
                     /locus_tag="VXC78_000022"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20010..20012,aa:Asn,seq:gtt)
     gene            complement(20090..20632)
                     /locus_tag="VXC78_000023"
     CDS             complement(20090..20632)
                     /locus_tag="VXC78_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV0582186.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20811..21578
                     /locus_tag="VXC78_000024"
     CDS             20811..21578
                     /locus_tag="VXC78_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV0582187.1"
                     /translation="MIGISLIPALYNIIFLSSMWEPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQGLQGSLENLQNQSSNLST
                     LKNQANQVLPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21582..22001
                     /locus_tag="VXC78_000025"
                     /pseudo
     CDS             21582..22001
                     /locus_tag="VXC78_000025"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22029..22343
                     /locus_tag="VXC78_000026"
     CDS             22029..22343
                     /locus_tag="VXC78_000026"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV0582188.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22444..24996)
                     /locus_tag="VXC78_000027"
     CDS             complement(22444..24996)
                     /locus_tag="VXC78_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV0582189.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSNLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQILKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLNRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(25058..26680)
                     /locus_tag="VXC78_000028"
     CDS             complement(25058..26680)
                     /locus_tag="VXC78_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0582190.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEIQAKVKELWKD"
     gene            26886..27911
                     /gene="trpS"
                     /locus_tag="VXC78_000029"
     CDS             26886..27911
                     /gene="trpS"
                     /locus_tag="VXC78_000029"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV0582191.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            28063..29541
                     /gene="guaB"
                     /locus_tag="VXC78_000030"
     CDS             28063..29541
                     /gene="guaB"
                     /locus_tag="VXC78_000030"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV0582192.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29592..30689)
                     /gene="recF"
                     /locus_tag="VXC78_000031"
     CDS             complement(29592..30689)
                     /gene="recF"
                     /locus_tag="VXC78_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV0582193.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(30692..31060)
                     /gene="yaaA"
                     /locus_tag="VXC78_000032"
     CDS             complement(30692..31060)
                     /gene="yaaA"
                     /locus_tag="VXC78_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV0582194.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            31219..32469
                     /locus_tag="VXC78_000033"
     CDS             31219..32469
                     /locus_tag="VXC78_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0582195.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32466..33749
                     /locus_tag="VXC78_000034"
     CDS             32466..33749
                     /locus_tag="VXC78_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0582196.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33791..34612
                     /locus_tag="VXC78_000035"
     CDS             33791..34612
                     /locus_tag="VXC78_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0582197.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKISFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34623..35168
                     /gene="pgsA"
                     /locus_tag="VXC78_000036"
     CDS             34623..35168
                     /gene="pgsA"
                     /locus_tag="VXC78_000036"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV0582198.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            35165..35992
                     /locus_tag="VXC78_000037"
     CDS             35165..35992
                     /locus_tag="VXC78_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0582199.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35977..36816
                     /locus_tag="VXC78_000038"
     CDS             35977..36816
                     /locus_tag="VXC78_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0582200.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36809..37603
                     /locus_tag="VXC78_000039"
     CDS             36809..37603
                     /locus_tag="VXC78_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0582201.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37662..38480
                     /gene="mreC"
                     /locus_tag="VXC78_000040"
     CDS             37662..38480
                     /gene="mreC"
                     /locus_tag="VXC78_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV0582202.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38480..38974
                     /gene="mreD"
                     /locus_tag="VXC78_000041"
     CDS             38480..38974
                     /gene="mreD"
                     /locus_tag="VXC78_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV0582203.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            39068..40246
                     /locus_tag="VXC78_000042"
     CDS             39068..40246
                     /locus_tag="VXC78_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV0582204.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40470..41249
                     /gene="rpsB"
                     /locus_tag="VXC78_000043"
     CDS             40470..41249
                     /gene="rpsB"
                     /locus_tag="VXC78_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV0582205.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41328..42368
                     /locus_tag="VXC78_000044"
     CDS             41328..42368
                     /locus_tag="VXC78_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV0582206.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42615..42938
                     /gene="tnpB"
                     /locus_tag="VXC78_000045"
     CDS             42615..42938
                     /gene="tnpB"
                     /locus_tag="VXC78_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0582207.1"
                     /translation="MIIQLSDLGQVHLVCSKIDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENVRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
     gene            complement(43093..43401)
                     /locus_tag="VXC78_000046"
                     /pseudo
     CDS             complement(43093..43401)
                     /locus_tag="VXC78_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43392..43790
                     /locus_tag="VXC78_000047"
     CDS             43392..43790
                     /locus_tag="VXC78_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0582208.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(43987..44907)
                     /gene="cysK"
                     /locus_tag="VXC78_000048"
     CDS             complement(43987..44907)
                     /gene="cysK"
                     /locus_tag="VXC78_000048"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV0582209.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(45192..45827)
                     /locus_tag="VXC78_000049"
     CDS             complement(45192..45827)
                     /locus_tag="VXC78_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV0582210.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            45883..47181
                     /locus_tag="VXC78_000050"
     CDS             45883..47181
                     /locus_tag="VXC78_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0582211.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILAEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            47178..47840
                     /locus_tag="VXC78_000051"
     CDS             47178..47840
                     /locus_tag="VXC78_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV0582212.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTIGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            47920..48468
                     /gene="raiA"
                     /locus_tag="VXC78_000052"
     CDS             47920..48468
                     /gene="raiA"
                     /locus_tag="VXC78_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV0582213.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            48604..50577
                     /locus_tag="VXC78_000053"
     CDS             48604..50577
                     /locus_tag="VXC78_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV0582214.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            50574..51026
                     /gene="rplI"
                     /locus_tag="VXC78_000054"
     CDS             50574..51026
                     /gene="rplI"
                     /locus_tag="VXC78_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV0582215.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            51070..52422
                     /gene="dnaB"
                     /locus_tag="VXC78_000055"
     CDS             51070..52422
                     /gene="dnaB"
                     /locus_tag="VXC78_000055"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV0582216.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            52424..52690
                     /locus_tag="VXC78_000056"
     CDS             52424..52690
                     /locus_tag="VXC78_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582217.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            52779..54125
                     /gene="cbpD"
                     /locus_tag="VXC78_000057"
     CDS             52779..54125
                     /gene="cbpD"
                     /locus_tag="VXC78_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV0582218.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      54208..54310
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            54381..54671
                     /locus_tag="VXC78_000058"
     CDS             54381..54671
                     /locus_tag="VXC78_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV0582219.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETPH"
     gene            54634..55392
                     /locus_tag="VXC78_000059"
     CDS             54634..55392
                     /locus_tag="VXC78_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0582220.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            55430..56437
                     /locus_tag="VXC78_000060"
     CDS             55430..56437
                     /locus_tag="VXC78_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0582221.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            56437..57165
                     /locus_tag="VXC78_000061"
     CDS             56437..57165
                     /locus_tag="VXC78_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582222.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            57284..57742
                     /locus_tag="VXC78_000062"
     CDS             57284..57742
                     /locus_tag="VXC78_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV0582223.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            57744..60176
                     /locus_tag="VXC78_000063"
     CDS             57744..60176
                     /locus_tag="VXC78_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0582224.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            60497..61150
                     /gene="rr06"
                     /locus_tag="VXC78_000064"
     CDS             60497..61150
                     /gene="rr06"
                     /locus_tag="VXC78_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV0582225.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            61147..62478
                     /gene="hk06"
                     /locus_tag="VXC78_000065"
     CDS             61147..62478
                     /gene="hk06"
                     /locus_tag="VXC78_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV0582226.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            62561..63088
                     /locus_tag="VXC78_000066"
     CDS             62561..63088
                     /locus_tag="VXC78_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV0582227.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            63167..65224
                     /gene="pspC"
                     /locus_tag="VXC78_000067"
     CDS             63167..65224
                     /gene="pspC"
                     /locus_tag="VXC78_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV0582228.1"
                     /translation="MFASKSERKVHYSIRKFSVGVASVVVASLFLGGVVHAEGVRSGD
                     TPKVTSSGQDISKKYADEVKSHLEKILSEIQLDKRKHTQNLAFNKKLSRIQTEYFYLK
                     KKLKAELTSKTKEELTSKTEELTSKTKKELDAAFEQFKKDTLSTEPEKKVAEAEKKVA
                     EAKKKAEDQKEEDRRNYPTNTYKTLELEIAEFDVKVKEAELELLKEKAKESRDEEKIK
                     QAEAEVESKQAEATRLENIKTDRKKAEEEAKRKADAKLKEANVATSDQGKPKGRAKRG
                     VPGELATPDKKENDAKSSDSSVGEETLPSSSLKSGKKVAEAEKKVEEAEKKAKDQKEE
                     DRRNYPTNTYKTLELEIAESDVKVKEAELELVKEEAKEPRDEEKIKQAKAEVESKQAE
                     ATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAP
                     KPENPAEQPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATG
                     WLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGDMA
                     TGWLQNNGSWYYLNANGDMATGWLQNNGSWYYLNSNGAMVTGWLQNNGSWYYLNANGD
                     MATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGE
                     WVN"
     gene            complement(65454..66434)
                     /gene="dusB"
                     /locus_tag="VXC78_000068"
     CDS             complement(65454..66434)
                     /gene="dusB"
                     /locus_tag="VXC78_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV0582229.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(66421..67293)
                     /gene="hslO"
                     /locus_tag="VXC78_000069"
     CDS             complement(66421..67293)
                     /gene="hslO"
                     /locus_tag="VXC78_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV0582230.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            67458..68885
                     /locus_tag="VXC78_000070"
     CDS             67458..68885
                     /locus_tag="VXC78_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0582231.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            69044..70552
                     /gene="glpK"
                     /locus_tag="VXC78_000071"
     CDS             69044..70552
                     /gene="glpK"
                     /locus_tag="VXC78_000071"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV0582232.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            70594..72420
                     /gene="glpO"
                     /locus_tag="VXC78_000072"
     CDS             70594..72420
                     /gene="glpO"
                     /locus_tag="VXC78_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV0582233.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESNWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVKAALAQNDLAELKN"
     gene            72488..73192
                     /locus_tag="VXC78_000073"
     CDS             72488..73192
                     /locus_tag="VXC78_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0582234.1"
                     /translation="MMSELFGEFLGTLILILLGNGVVAGVVLPKTKSNSAGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            73489..73692
                     /locus_tag="VXC78_000074"
     CDS             73489..73692
                     /locus_tag="VXC78_000074"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582235.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(73779..74387)
                     /locus_tag="VXC78_000075"
     CDS             complement(73779..74387)
                     /locus_tag="VXC78_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582236.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            75426..76703
                     /gene="ltrA"
                     /locus_tag="VXC78_000076"
     CDS             75426..76703
                     /gene="ltrA"
                     /locus_tag="VXC78_000076"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEV0582237.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            77159..78337
                     /locus_tag="VXC78_000077"
     CDS             77159..78337
                     /locus_tag="VXC78_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0582238.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            78651..78782
                     /locus_tag="VXC78_000078"
     CDS             78651..78782
                     /locus_tag="VXC78_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV0582239.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            78803..80353
                     /gene="dltA"
                     /locus_tag="VXC78_000079"
     CDS             78803..80353
                     /gene="dltA"
                     /locus_tag="VXC78_000079"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV0582240.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVFTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            80350..81594
                     /gene="dltB"
                     /locus_tag="VXC78_000080"
     CDS             80350..81594
                     /gene="dltB"
                     /locus_tag="VXC78_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV0582241.1"
                     /translation="MMEFFQQLPHLEPYGKPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQFLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            81608..81847
                     /gene="dltC"
                     /locus_tag="VXC78_000081"
     CDS             81608..81847
                     /gene="dltC"
                     /locus_tag="VXC78_000081"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV0582242.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            81840..83108
                     /gene="dltD"
                     /locus_tag="VXC78_000082"
     CDS             81840..83108
                     /gene="dltD"
                     /locus_tag="VXC78_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV0582243.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            83263..83703
                     /gene="adcR"
                     /locus_tag="VXC78_000083"
     CDS             83263..83703
                     /gene="adcR"
                     /locus_tag="VXC78_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV0582244.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            83703..84407
                     /locus_tag="VXC78_000084"
     CDS             83703..84407
                     /locus_tag="VXC78_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0582245.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            84400..85206
                     /locus_tag="VXC78_000085"
     CDS             84400..85206
                     /locus_tag="VXC78_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0582246.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            85216..86721
                     /gene="adcA"
                     /locus_tag="VXC78_000086"
     CDS             85216..86721
                     /gene="adcA"
                     /locus_tag="VXC78_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV0582247.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRASLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQETLFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(87891..88664)
                     /locus_tag="VXC78_000087"
     CDS             complement(87891..88664)
                     /locus_tag="VXC78_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0582248.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            88840..90243
                     /locus_tag="VXC78_000088"
     CDS             88840..90243
                     /locus_tag="VXC78_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV0582249.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLVDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            90358..90996
                     /locus_tag="VXC78_000089"
     CDS             90358..90996
                     /locus_tag="VXC78_000089"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV0582250.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            91008..91448
                     /locus_tag="VXC78_000090"
     CDS             91008..91448
                     /locus_tag="VXC78_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV0582251.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            91441..91872
                     /locus_tag="VXC78_000091"
     CDS             91441..91872
                     /locus_tag="VXC78_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0582252.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            91863..92333
                     /locus_tag="VXC78_000092"
     CDS             91863..92333
                     /locus_tag="VXC78_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0582253.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            92358..93131
                     /locus_tag="VXC78_000093"
     CDS             92358..93131
                     /locus_tag="VXC78_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0582254.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            93128..93928
                     /locus_tag="VXC78_000094"
     CDS             93128..93928
                     /locus_tag="VXC78_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0582255.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            93987..96281
                     /locus_tag="VXC78_000095"
     CDS             93987..96281
                     /locus_tag="VXC78_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0582256.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            96291..99407
                     /locus_tag="VXC78_000096"
                     /pseudo
     CDS             96291..99407
                     /locus_tag="VXC78_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            99490..101256
                     /locus_tag="VXC78_000097"
     CDS             99490..101256
                     /locus_tag="VXC78_000097"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV0582257.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAILGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRS
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            101402..102553
                     /locus_tag="VXC78_000098"
     CDS             101402..102553
                     /locus_tag="VXC78_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV0582258.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMAINGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGYDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            102698..103582
                     /locus_tag="VXC78_000099"
     CDS             102698..103582
                     /locus_tag="VXC78_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0582259.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(103700..103777)
                     /locus_tag="VXC78_000100"
                     /pseudo
     CDS             complement(103700..103777)
                     /locus_tag="VXC78_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            103981..104233
                     /locus_tag="VXC78_000101"
                     /pseudo
     CDS             103981..104233
                     /locus_tag="VXC78_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            104221..104511
                     /locus_tag="VXC78_000102"
     CDS             104221..104511
                     /locus_tag="VXC78_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582260.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(104916..106247)
                     /locus_tag="VXC78_000103"
     CDS             complement(104916..106247)
                     /locus_tag="VXC78_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV0582261.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(106269..107780)
                     /locus_tag="VXC78_000104"
     CDS             complement(106269..107780)
                     /locus_tag="VXC78_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV0582262.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(107991..108938)
                     /gene="arcC"
                     /locus_tag="VXC78_000105"
     CDS             complement(107991..108938)
                     /gene="arcC"
                     /locus_tag="VXC78_000105"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV0582263.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(109103..110116)
                     /gene="argF"
                     /locus_tag="VXC78_000106"
     CDS             complement(109103..110116)
                     /gene="argF"
                     /locus_tag="VXC78_000106"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV0582264.1"
                     /translation="MNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHYL
                     AGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITEDA
                     DEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPAF
                     HDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLYI
                     PKV"
     gene            complement(110177..111406)
                     /gene="arcA"
                     /locus_tag="VXC78_000107"
     CDS             complement(110177..111406)
                     /gene="arcA"
                     /locus_tag="VXC78_000107"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV0582265.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            112161..113840
                     /locus_tag="VXC78_000108"
     CDS             112161..113840
                     /locus_tag="VXC78_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0582266.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGE
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGVEVS
                     GSALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(113880..115964)
                     /locus_tag="VXC78_000109"
     CDS             complement(113880..115964)
                     /locus_tag="VXC78_000109"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV0582267.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKSSAQVDWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSTCKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLNKTLVSTIQHQDLLKAE
                     QLIFTLSWLPNH"
     gene            116135..117415
                     /locus_tag="VXC78_000110"
     CDS             116135..117415
                     /locus_tag="VXC78_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV0582268.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFVELDLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPLALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            117506..120151
                     /locus_tag="VXC78_000111"
     CDS             117506..120151
                     /locus_tag="VXC78_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV0582269.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQAECAKWGKSTQIGYFPDTFGNMGQAPQILQQSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGADGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVCTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRILVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            120235..121104
                     /locus_tag="VXC78_000112"
     CDS             120235..121104
                     /locus_tag="VXC78_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0582270.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHCFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAGKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNCNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            121098..122978
                     /locus_tag="VXC78_000113"
     CDS             121098..122978
                     /locus_tag="VXC78_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0582271.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            123392..123607
                     /locus_tag="VXC78_000114"
     CDS             123392..123607
                     /locus_tag="VXC78_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582272.1"
                     /translation="MILWSFDFVNAHAHAFFMDNVEWSHADSYFLSFVSDDVEERYTE
                     NVYLDSLSVKQKFKFLFDFGDEWRFEC"
     gene            complement(123788..124636)
                     /locus_tag="VXC78_000115"
                     /pseudo
     CDS             complement(123788..124636)
                     /locus_tag="VXC78_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(124581..124763)
                     /locus_tag="VXC78_000116"
     CDS             complement(124581..124763)
                     /locus_tag="VXC78_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0582273.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            125098..>126484
                     /gene="pcpA"
                     /locus_tag="VXC78_000117"
     CDS             125098..>126484
                     /gene="pcpA"
                     /locus_tag="VXC78_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV0582274.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSVI
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGV"
BASE COUNT        39055 a        22305 c        26280 g        38844 t
ORIGIN      
        1 ttacggatat agtctaaaat tcgatttcga aacttggttt tgaaatattt ccttaaacgt
       61 ggaatatcgt ctaccagtcc ttcttctcta ctaatcaatt catgtaagca gagcatgcct
      121 tcttggtccc aatccgacaa ttcccataaa tgaaggtaat attcatttct acacttatac
      181 acagtccctt ggacttcttc atacaattct ttaatcataa ttttcccctt tctagataca
      241 gtctaacaga ttagaaaaca catttgttcc attttctcca ttctgttccc tttagctcct
      301 aaactgcaca aaaaagagag gctccagcct ctctcagggt tatttttcgt cattcatttt
      361 tgactttact tcatcatagg atagtgcatg agattcctct tctactgctt caggcatctt
      421 tcctgtttcg taaagagctt taatttgtgt actatccaat gtttcgtatt tcaataatgc
      481 ttctgcaatt aacttgtgag tttcacgatt tgactgaata atttcagcag ctttatttcg
      541 tgcctcattt aataatgaac gaacctcttc atcaatttca taagctgttt gttctgaaat
      601 tgatttttga ggattctgtg caccaaacat agcatggttt ccttcatatt gtactgggcc
      661 aagtttttca ctcataccgt actctgtaac cattgcacgt gccatttgtg tcgcttgttc
      721 aaagtcgttt gaagctcctg tagtttggac attaaagata atttcttcag ctacacgtcc
      781 acccattaag ccagccaatt gctctttcat atcttcttta gatagaagca tttgatcctc
      841 tttaggaagt gcaatcatgt atccgcctgc acggccgcgt ggtacaattg taaccttatg
      901 gacaacgcga gcattcgaca agactagacc aacaatggta tgtcctgcct catggtaagc
      961 aaccaattct cgttcttttt gtgaaactgt cttatctttc ttagaaggtc cagcaataac
     1021 tctatcttct gcttcatcaa tatctgaagc atcaattatc gatttattgc gacgagcagc
     1081 aactaaagct gcttcattca agacattctc taaatcagca ccaacaaagc ctggagtttg
     1141 ttgagccact aatttcaaat caacatcttc tgctaaaggc ttgttcttag cgtgaacttt
     1201 caagattgct tcacgacctt taacatcagg acggccaacc aatacttttc tatcaaaacg
     1261 tcctggacgc aaaagggcag gatcaagtac atctgaacgg tttgtcgcag cgatgacgat
     1321 aatcccttca tttccctcaa aaccatccat ctcaatcaaa agttggttca aggtttgttc
     1381 acgttcgtca ttacctccgc cgagaccgac tccacgttga cgtccaacag catcaatttc
     1441 atcgataaag atgatagctg gtgctgcttt tttggcatcc tcaaaaagag agcgaacacg
     1501 actagctcca actccgacaa acatttctac aaagtcagaa cctgagatac taaagaatgg
     1561 aacacctgct tctccagcga ctgccttagc aagcaaagtt ttacctgtcc ccggaggtcc
     1621 ctccaaaaga acacctgctg gaatacgggc tccaagtttt gtgaatcgtt ttggatcttt
     1681 taagaactca acaacttcaa ctagttcttg tttttcttct tcagctccag caacatctga
     1741 aaatcttact ttaatatctt ctttatttgc tgctttagcc ttactacgtc caaaactcat
     1801 tggattacgg ccattgcctc ctcccatatt tcccatcata gagaatagga agaagaatag
     1861 aattccaaat ggcacaatgg atacgagtag attaatccat ataccacttg aactttcatg
     1921 cttaacagtt acttctgctt tatggtcagt agcaagtttt tgcaattctg atacggtagt
     1981 atctgcagga agaatagtgc tggtaaattt ctctacctta gtaacagatg gcgtgaaaaa
     2041 ctgaatacct gttccttctt tacttgtttt aggattttta tagacaccag aaacttcgat
     2101 aacactacca tttggttggt aagttaattc ttttacatta ccatcggtaa tttcttgtac
     2161 caactcagta tagttgattt gctgacttcc tcctgagtta ttcccagaat agaaatactg
     2221 gaatcctgtc acaaggaaaa agataaataa taaccataga aaaggatttt taattaaacc
     2281 attattttgt tttttcatta aagattattc tttctaattt gaatacactt cctctttcaa
     2341 tactccaata taaggaagat tacgataatt ttctttgtag tctaaaccat aacctactac
     2401 aaactcattt gggatagtaa agcaggtata gtctgcctca atttctacaa cacgtccttc
     2461 tggtttatcc aacaaggttg caattttaac agaagctgct tctctttctt taaacatatc
     2521 tcgcaaattc ttcaaagttt gacctgtatc aatgatatct tctacaaata gaacatgtct
     2581 tcctttgata tcttgagtca catcttgttt aatattgata acaccactac ttgctgttcc
     2641 accatggtag ctagaaacca tcatgaagtc catttcaata tgtgtatcaa tatgtttgac
     2701 caattcagcc ataaaaggaa tagatccttt taaaatccca actaagattg gattttttcc
     2761 tgcatagtct ttagttaatt gagcacctag ttttttagct gcttctgtaa tttcatcgtg
     2821 tgaaacgagg acttttttaa tatcgttttc taacattttt tacctatcta ttttttctat
     2881 ataaagtaca gtgttaatta tatcattttt cgttttttta ctcaaattat tggtcgcaat
     2941 tcccaaaatt gagacaattt caccaaattg ctcaataata agagcagagt ttctcttttc
     3001 catagggatt ttcaaatcaa taaataaacg tctgagtttt tttctatgcc cattttgaat
     3061 caaaacatct cctgtttttc gatgacgaat gtgtatggat gtttcacgtg aaacaggtat
     3121 ttgttgaatt aattcacctt ctaatggaag tccaaaggaa aataaatatc cttgataagc
     3181 tacctgattt tgatagtgta acacaagttc atcttccttt tcatcagcct gcggactgat
     3241 tttacaaatc tgaaactgtt ggtactcttt tatcaattca tagccatttt taatcggatg
     3301 acgatactgg cttttagatt ttaaaatctg ctgaacttca gcaaactgag cttttgtaag
     3361 attcaaatct ggaaaacgat tcagataagt ttgaagtaaa actctttgtg tagactcaga
     3421 gtaagaaaat aactgctgta aatcttccac attaatattg ttagataatt cagctattgc
     3481 caaatcataa tctaaaattt cattgccaat gcctaagatt gcatccctaa atcgaggatt
     3541 ttctttttcc aattctggta agtaagagtt tcgaatacga tttcgaaaat aatgattctc
     3601 ctgatttgat gtatcttcaa agtgaaaaat tgatggaaag tcttttttct gaaaatgcaa
     3661 gaagggacga atgatttcta tctctccgac tacttgcttc tccttaattc ctgatagata
     3721 gcgcaagcga gttcctcgaa tcaagcgcat caaaatcgtt tccacctgat catcagcatg
     3781 gtgggcagtg actaaagctg tcgcacctgt ctttttcata acctcttgaa aaaaatcata
     3841 acgaaaattt cgtgcacgcg cttctgaaaa ttctcctgaa aaattgctga tataaatagg
     3901 aagctctgct tcagcagcca acttccttaa ttccttttct tcccaatctg attcaattct
     3961 ctgcttatga ttcacatgag ctagaatcaa ttcaatctct aactcttttt gataagtaga
     4021 caatacctta aatagaaaca tggaatctaa tccaccagaa agagctagaa ccgccttagc
     4081 atgctttttg aaatatccct tcttgagaaa atgatttaaa aaatctggtt ccctcatttt
     4141 agaacctcat aaacatcctt ggctatctta gaaatcgtat cataatcaga attcttagtg
     4201 aaaatagaaa gaataaatgg agaatctgca tagacaacac ccgtatcatg cttaaattca
     4261 tccgcatctc caattttatg agctacttta acagaaacac ctttggcaat tcgctgacta
     4321 tcaaaatctg ttttagtcaa agactctagc acaaatccat tttgattata aatagcttcc
     4381 ataaacttcc cggccatctt agaagaaatc aatttttctt ttggatccca atcatctccc
     4441 ataatggcag acatcttgga tttgaatgtg gcatcagatt ggtttgaaat gtaatatccc
     4501 aatagattat gagctacatt atcagattct tttgatactt tcgtaattaa atcctttaaa
     4561 gaatattctt tattatcttc ttttttagga agactaccac ttccctctgg tttataagaa
     4621 cctggaaaat cattgactgc agatacgtat tttacagtcg tatctaactg ataaagaccc
     4681 tcatttattt tttcttgcgt ataatagaga taggagagtt tcaaaacgct ggctgcatac
     4741 atcttttcat cttgattgat accagcttct tttccagtag tcagttgctt aacataaata
     4801 gagaaagaat ctttctgata tttttcagat aacatttctt gaactttact catccgatta
     4861 tcttcttcag aagttgattc tttagctacc catccagcct gatcaatatg tagaaattct
     4921 cttccttcta caaacatggt cttgtcgatt gatacttgcg aataagctga taaggatgat
     4981 ttcacttctt ttaaatcata aggactattg tacagtttaa agtcagattc taaccatgct
     5041 ttttttattg ttggagttac ctctgattga tcatataaaa atcgtttgtc cgcagctata
     5101 aattgatgat ttgatagctt aaatactgga attccttgtt tatttaagcg ccactcggtt
     5161 atttgaaaac ttgttttggg agtcaatttc ccagattcca ctactaaatc ttcattcgca
     5221 taaacaggaa cctctccata aaccatggga gaacttaatt tttctctaaa ataaatacta
     5281 aagtcagatt gtgaaaggta ataaatttct ttcgaagtat agacgacttc tttttctgtg
     5341 ctaacgactt ttgaaatggt caaaaaactt ggtagcaaca aaataattaa gaatttacgc
     5401 attcttcctt tccttttctt cttgtaaacg caataattga tttttatcag ccaattcttc
     5461 cagcttttca tctgacaaac tcaaaaattg ctctattacg tctaataaat tttccatttt
     5521 atcacctttg aagcaagtca ggaatcgtat aaactttttc cctcgactta gaataatagt
     5581 acttcgctcg tgtatattta gcagcataat cttcatcttt caacttggta gcaaatgctg
     5641 tctccttatc cttttcatca ctcaaagttt gatactgagt ttgcaagtct gctaattgct
     5701 gacgtctttg gagtaattgc tgataactct gcgctaaatt aaaagttggc aagataaata
     5761 atagcataat caaaatcaat acccctccca taaaacgatt ccgtttttgt cgttctttca
     5821 tcaggtagcg acgacgttgg tattcatttt gaataaaaga attattcaat tgtacaatat
     5881 ttttagacat tttcttctac ccgtgtttca ctgataattt catacattcc tgctgcatct
     5941 tctttttttg tactatcttt catctctagt acttttacaa gcagcaactt attgccaaag
     6001 cgaatttcaa cttggtcatt aactttcaag tccgttgaac ttttggccaa gattccatta
     6061 accttgattc tacctttatc tgctacttcc tttgcgactg tacgacgctt gataattcgc
     6121 gatactttta aatatttatc taatctcatc cttattacct caatttatta ttgtaccatt
     6181 tttatctatt ttatagaaga aaaatatcaa atggaatttt cttccttaaa ctcttttatc
     6241 tctaataaac tttctccaaa aatcagcaga ccttctaaaa tttcataatc tttcttattt
     6301 tggacatcaa atacaagctc cattaatccc ttattctcag cgatgcctgc ttttaagttc
     6361 gttacggata aagctttaaa ataatcttga gctaaaaaca gccgttgagt gactttttca
     6421 aattgaattg taattttatt atcttttctt tccacacgtt gaacaaagac cttgtccaag
     6481 tatgatttaa ccaaaccaat ctctaaaaga taggctacta catctgggta ttctccaaaa
     6541 cggtctatca actcctcttg taactcttca taattgacac ggttgtcaat ttgacgaatt
     6601 ttcttgtaaa tttcaatctt atgtcgttga tcagaaatat aagtatcagg aagataggca
     6661 tcaatttgca aaatcaactc agcattccct ttggttcttg tgttagcgtt agcattaccg
     6721 tttcgtttag caatagcttc ctctaataac tgcgaataca attcaaaacc aacagaatca
     6781 atgaaaccag actgggattt tcctaaaaga tttcctgctc cacgaatcga aagatctcgc
     6841 attgcaatct taaagccaga gcccaattct gtaaatcctt taatcgcttc taatctcttt
     6901 tcagagactt cactgattga tttttctgga cgatacatga gataagcata agcaatacga
     6961 ttactacgac cgactcttcc tcttaactga tataaggttg acaagcccat atggtccgca
     7021 ttttcaataa ataaagtatt agcatttgga atgtccaccc ctgtctcaat aatagtagtc
     7081 gtcaccaaga tatcgtattg tccctcaata aagtctaata gagtattttc caactggact
     7141 tcactcattc gaccatgaac atatccaatc gaagcctccg gaatcaactc ctgtaattct
     7201 gaaaccttct gaacaattgt gtcaactttg ttgtaaagat aataaacttg acctccacgc
     7261 tccatttcac gcaagacagc atcacgaatg acactatcat tcttttccaa aacataggtc
     7321 tgaacaggat agcgattagt cggcggagtt tcaataacag ataaatctct gattcccagc
     7381 atagacatat ggagggtacg agggattggc gtagcggtca aggttaggac atccacttgt
     7441 ttcttcagtt ctttcaaagt ttccttatgc ttgacaccaa atcgctgttc ctcatcaata
     7501 atcatcaagc ccaaatcagc aaacacaaca tcttttgaca aaacacgatg tgttccaatc
     7561 aaaatatcga cttgaccgtt tttcaatttt tcaagtgttg cagtctgctc ttttttactt
     7621 ctaaagcgac tcaacacatc aacattaact gcaaaatttt ggaatcgttc cttaaaattc
     7681 gtatagtgct gttgcgctaa aaccgtcgtc ggaactagaa tgacaacctg tttgtgatca
     7741 ttgactgctt taaaggctgc acgcatagca acttcagtct ttccaaaacc aacatcccca
     7801 actaaaagtc gatccattgg ctgagaagcc tgcatatccc tcttgatttc ctcaatacta
     7861 cgaagttgat catccgtttc aacataaggg aaagcatcat caaaggcatc ttgatcatca
     7921 tcatcagctg agaaagcaaa acccttcaac tgactacgtt cagagtagag tttgattaaa
     7981 tcatcagcta tatcctctac ctggttctta accttttgct tggccttttt aaaatgaccg
     8041 tcatttaatt tattgagttt tggagcttta ccatcacttg aaatatattt ggacagtaga
     8101 tgaatctgtt ccacggggat agaaatttga tcaccatttt ggtattggac actgacataa
     8161 tcgcgatgaa ttcccttgat ttcaatggtt tcaattccta gatattgacc aatcccatgg
     8221 atatgatgga caacatagtc ccctttttca agttcattgt aatcttttaa tctctctgca
     8281 tttgaaacat gttgtcttcg aaaacgacgc tttaatttct tttgaaaaat ctcatgttca
     8341 gttatcaata aaatcttttc atctacaaaa tgaaaaccat gtctgagatt accctctatt
     8401 aagtttacag attctttaca gatacttgtc ttatctctag aatccaattt aatctgatat
     8461 tcctctaaca tatcctccaa tgttttactt cccattgaat tgctagactg cagaataatg
     8521 gtgtaatcca tttttttata tcgttcaatt tcttctttta gaaaagaaaa ctgattgaaa
     8581 aattcctgca taggatattg attaaattga taaattttgt caaatttgag atttcctaaa
     8641 cccttttgaa gattagagaa aaaggtcact ggactttgtt ttttatagat ttgttcaata
     8701 tcagaaaaat actgcatatc agaaaatgct ttactattct gtaattcttc tgtaaagtac
     8761 tgcgctaagt ctctttcaaa gacttcatac tgattcatca atttttgata atcatcaaag
     8821 aatattggag tatctttttc aatataatca aagacagtcc atgtcttatc atagcacaaa
     8881 gataaaaact tccgagagtc tgcatgactt tgtttttggt gaaaacttga aagaatttct
     8941 tctaggtatg atttcaaaat aggtgataaa gtttttgaaa tttgtttttc taaagctgac
     9001 tgtcctcgtt gataatcctt ttctctcaaa agcatatcac tagctggaaa gatagtgagt
     9061 tctgtcttat tttctttcga taattgtgtt tctacttcaa atgacctgat accatcaatt
     9121 tcatcaccaa aaaactcaat tcgacaaggt tctaactggg atatttcaaa aatatctaaa
     9181 atatctcctc gaagactaaa ttcgccctga gtttgtactt gagtaacttt tcgatagcca
     9241 ttttccttta actgatggat aaacgcgtgt tgatcatatt cttcaccaac tgagattttt
     9301 acaatactat ctttgaatgc attgggagac ggtaaaatca atcgacttgc tgcgatatta
     9361 caaactaaaa tccctttctt agatgaatca gtcaaaaaac gcaaggcttc aacccgtgaa
     9421 ataatttttt cctgtgaaga catcaaaaac tccaccatag gagcatcatc taccaaaaat
     9481 ggatagacga gttcctcacc caagatagaa ataagatcac taacaagtcc ttctgcttct
     9541 ccataagttg acgtcaataa cacaatccta tcttcttttt ctaaactgct tgcaattgca
     9601 agagccttag tagatgttga taaaccaagt attagttgtc ttttcttatc tgttaaattt
     9661 tgatgccatt ttttaatctg atcattttct gagaataaat ctaataaggt caccatttat
     9721 ccgttatacc tctgcattgt tttctcaaaa tttttctctt gtaaatagta ttttacagaa
     9781 tcgtcaactt tgtcaacaga ctgtaaaata ccgatataat catccctgtc aaacttactc
     9841 aaaacatgat gaacaactga cataccattt ttaggtcttc caattccaat cttaacacgg
     9901 ttaaagacct gagttcctat atgttgaata atagacttga taccattatg accacctgct
     9961 gagccttttg ctcttaaacg aattttccca acttccatgt caagatcatc gtaaatgata
    10021 agtaaatcgt caatatccaa accatagtaa gttaataaag catgaactgc ttttccactt
    10081 tcattcataa aggtcgttgg tttaaccaga taaatttttt ctccatttag gaaaaaggat
    10141 gctaggtcag cttgaaatat cttatcgtgt gtaaaagtga cattctgttt cttcgctagt
    10201 tgatcaatca acataaaacc aacattgtgt tttgtttcaa aatatttatc ccctggattt
    10261 cccaagccta caagtaattt ggtcatttat ttttcctttc aaaagccaaa agggttggaa
    10321 ttttttttcc aacctaattg acaccattta ttaattttta gacattaaag cggaattcca
    10381 tgatatcgcc atcttgaacg atatattctt ttccttcttc acgcaagcgt ccagcttctt
    10441 ttacggcctt ttcagatccg tatttcacta gatcttcata tgacatggtt actgcacgaa
    10501 taaagccttt ttcaaagtct gagtggataa taccagctgc ttgaggagcc ttcataccac
    10561 gtttgaaagt ccaagcgcga acttcttttt caccagctgt gaagtaagtt cccaatccaa
    10621 gcaagtggta agctgcacgc gtcaacttat ctacacctga ttctgtcaaa ccaatggctt
    10681 caagaaactc ttttttatct tcatcatcca attcagaaat ttcttcctca gcacgcgcag
    10741 aaataacgac tacttcagca ttttctgtcg ctgcaaattc acgaatttgt ttgacatagt
    10801 cgatagagtc aggttctgaa accacatcct cgtccacatt agctacataa agaactggtt
    10861 tagtcgtcaa aaggaaaaga cctttgacaa ccttttgttc ctcatctgta aattcaatgg
    10921 tacgagctga tttcccgtct tctaggactg gtttaatctt ttgaagaaca ttgaattctg
    10981 ctactgattc tttatctttt tgcgtacgtg ccatcttttc tacacgcgca tatcgtttgt
    11041 tcactgattc taagtcagca agaatcaatt ccagattaat tgtatcaata tctgcaagtg
    11101 gatctacaaa ggcgtcttca cgtccttgct cgcgcatcac attttcatca tcaaaagcac
    11161 gaactacgtg aacaatcgca tctacttcac gaatattggc caagaattta ttccctagcc
    11221 cttctccttt tgaagctcct tttacaatcc ctgcaatatc tgtaaattca aatgttgtgg
    11281 gaactgtctt tttaggagtt atcatttcag ttagtttttg taggcgttca tctggaactt
    11341 ccaccattcc aacatttgga tcaatagtcg caaatgggta gtttgctgcc tctgctcctg
    11401 cttttgtaat tgcattaaat aatgttgatt taccaacgtt tggcaaacca acgatacctg
    11461 ctgtcaaagc catatttctc attctccgtt ttcatttcaa tccctaatat tataacacaa
    11521 aaagggataa agtgctaacc ctctaactaa gggttctcag tcaataattt tattcatttt
    11581 tcgctcaaaa tcatatcgcc ccatcatgac aacatgctca caattactgc attttatttt
    11641 gatatctgct cctacacgtg taatttccca acgattagcc tttttaccag tcgacttgat
    11701 tgtacaagcg tgtgattttt tcatctcaac aaaatttcca acttgataca tactactctc
    11761 cttttctttt tcgattatat cataaaagag gcgagccagg ctcaacctct ttcacttaat
    11821 ttgtacgaac tggtgtaatg agctgcatga agtcttcgtc agtatctgct ggcacaagag
    11881 taaatggacg aacagctgag ataaagctaa tggtcacctt ttcgctattt aaagctttaa
    11941 gagaatcaat caagtaagtt gggttgaaac taatggtcaa atcttcacca gtaacctgat
    12001 cagtatcgat ttcttcgttt actttaccaa cttctggaga gtgaacatgg gcgctaacaa
    12061 ccccatcctt aatttcaagt ttcacagtac cattttgagt cgcacttgat aaaagacggg
    12121 cacgctccat tgactggcgt aagtttacca cattaaaagt aatagtagtg ttaaagtctg
    12181 ttggaatcaa gcgatctgta tcaggatagt ttccttctag gagacgagta tagaagctaa
    12241 tattttcgct tctaaagagg atttggttat tggcaaagaa aatctctaca gtttcgatat
    12301 catctgtaaa taccgctgaa aattcgcgta gagaacggct aggaattacg acatcaaaat
    12361 catcactatt tttttcaaga gtcaattttt tctggcttag gcgatgagag tctgttgcaa
    12421 ctgtttttaa ctctttgtgt tgactcaata cgaagtggac acctgttaaa atcggacgac
    12481 tctcttgtgt acttgcagca aaggctgttt cattaataat tttcttgagt aattttgttt
    12541 caagtattaa aggagtgctt gctgaaattt cttggattcg tggatattgt tcgctatctt
    12601 ttccttttag ggtaatttct gatttgccac tggttaaaac aatttgattt tgttcaattt
    12661 ctttaaaatc aagagtcaca tcaggtaaac tagatactac attgataaag aaagaagctt
    12721 caagaaggat cgaacctaaa gaagtaatta acaaaccagc atcttcattt ttttgagaaa
    12781 taaaattttc aattgaaatt tgaccatttg aaccaattaa agtaatacct tcattggtca
    12841 cgtcaatttt tactgttgat aaaataggaa tggcattttt agaactaata gctctcttag
    12901 tagtatttaa tgcttgtaga aataaatttt tattaattga aaaatgaatc atggattctc
    12961 ctttatttat ttttagtatt agaaagataa tagtaataat agagtctgtg aaatctgtgg
    13021 aaaacagcct ttaaacaagt catatcaagt tttttagctt gtttaaaaaa tgtggataaa
    13081 aaagataaaa aactaaaagt tatccacaaa ttatttgatt ttctttttga ttgattcaat
    13141 ttctaaacgt aaattatcgt cttgatcaat caaagatttt attttggcat gggcatgaat
    13201 gactgtggta tgatcttttc ccccaaattc cttcccaatt tttggaagac tattatctgt
    13261 tagttctcta gataaataca tggctacttg acgggccaaa acaatatttt gaaggcgtct
    13321 acttcccttc atttctttga tactaacacc ataaaagtta ccaacttcag tttggatttt
    13381 atcaattggg atgacgagca tttggctaac atcttgtttg cgggctctaa tggcttctgc
    13441 agcaatatca atagtgatat ccttgatttt ttttactctg gcaattaaag tgatgtcgtt
    13501 gatggctccc tcaagatctc gaacatttga atcaaattgc ccagctaggt attctagagt
    13561 atcactttgg aaattgtagc ctaaatgttc cgttttactt tgtaaaatgg caatacgtgt
    13621 ttcaaagtca gggggtgtga tagtttgtgt caatccccaa ctaaaacgcg tgacaagcct
    13681 ctcctcgagc ccttctagat gttttggact acgatcactc gttaggacaa tctgtttttg
    13741 cttgtcatga agggcgttaa aggtattgaa aaattcttcc tgagttgcga ctttttttcc
    13801 gctgagtgac tgtatatcat cgattaacaa aagatcaaga ctacgatagg tctttttaaa
    13861 cttttccatt tccccaagtc ttaggtgatc aagaaagtca ttaataaagc tttcggcagg
    13921 gatatattta acacgcgcat taggaatatt ttttagaatt tcatttccaa tagcgtttaa
    13981 taagtgagtc ttaccaaggc ctggtcctcc atagataaaa agagggttat aggtcagagc
    14041 caaatcttca gagacagcta aagcggctga tacagcccaa acatttccat ccccttgaat
    14101 aaagttatca aaggtatact tttcttttaa tcccgtatct gaataaggaa tagatactaa
    14161 ctttggacta tagtcataaa gagttaaatt tgtagcttct tcaacttgtg agctagtcgt
    14221 atcttgaggt ttggtgaaaa tatagtgggg agttatttca gcgtcataaa tttcaaaacc
    14281 agctactaca ataatatctt ttagttgttt ttcccagacc atttccattt cagagcgagg
    14341 tagaaatata gtggcaacat tttcctctac cttgatgagt tcagcttgaa tagcatagaa
    14401 atcatacatg gatcgagtca gtctttcttg tgcaaattct aatatacgat tccaaaattg
    14461 tttttctttc aatcctttct cctcctttac tatttaaaag tttaatacta gagatatttt
    14521 accatagata gcaagaattt tccacaagct gtgaaaaata atccacaatg ttactaaact
    14581 ttatccacag gttggggata aaagaagaaa ttattgattt attaagcttt ttatcgaaaa
    14641 acatagtgga taaccttgtg agataaaaaa ataaaagaac agccttattt caggctgttg
    14701 ataattctac tatattcttc ttgatttgaa aaagaaataa tgatttttcc actgtctttt
    14761 ttagatagtt taatttctac atctaatccg agtagttttc ttaactgttt ttcttcattt
    14821 tgtatgaaat gattagtttt ttgctgtttc ttttgttttt tctctgtcag aagagcttct
    14881 aacttcctta cagaaatatc ttcttctata atccgttgaa agaaatagtc ttgttgttcc
    14941 ttatttaacc caactaggga acgcgcatgg gcttgtgata gtttgccatt ttctacttct
    15001 gagagaatct gttctggcaa ggaaagtaaa cgaatggagt tgctgatata tggacgagac
    15061 ttgcccatct tatctgcaat ttcagcatgg gtgaatcctt tctctacgag agattcatag
    15121 gcgcgtgctt cttctattgg gtttaaattt tctctctgta aattttcaat aatggactgg
    15181 accatcatct cttggtctga aatctgttta acaacagctg ggatagaccg tagaccagct
    15241 aaaagtgaag cccgatagcg tctctctcct gcaaggattt cataaccaat aacaggagat
    15301 tgacgaacaa taatcggttg aatgacccca ttttctttga tagactgtgc tagttcatct
    15361 agtttttctc tatcaaattc ttttcggggt tgatagggat ttttttgtat atctgtgata
    15421 gaaatcattt caaatttttc catgattcta cactaacaca tcttttctct tatgtaaagc
    15481 tttctttaca tagatgtcaa ttaagattct aaatcacctg aactcttgtt aagtttgata
    15541 gaggtagttt cttctttccc gttacgatag taggttatct taatggtgtc tccgatagaa
    15601 tggttgtaaa gagcactttg taaatctgtt gatgaagcaa tctctttgtc atctactttt
    15661 gtaattacat cgtatttttc aaggtgacca ttggcaggca tattactttg taccgaacga
    15721 acaactacac cagatgtaac attacttgga atattgagtc ttctgatgtc gcttgtactc
    15781 acattagata aattaaccat ctggattccc aaagctggac gagtcacttt tccgtttttt
    15841 tctaactgtt caataatatt gatagcatca tttgcaggaa ttgcgaaacc aagaccttct
    15901 acagatgttc ctccatttgt agcaatttta cttgaggtaa ttccgataac ctgcccttga
    15961 atattgatca gtgggccgcc agagttacct gggttaatag cagtatcagt ttggatggct
    16021 tttgtagaaa tagcttgtcc atcttccgat cttaaggata catttctatt gagactggat
    16081 acgatacctt gagtgacagt atttgcatat tcagaaccta acgggctacc gatggcaata
    16141 gcagtttctc ctacagttaa cttactagaa tcaccaaact cagctactgt tgtcactttt
    16201 tctgaagaga ttttgacgac agcaatatca gagaaagtgt cagctccgac aatttctcca
    16261 ggtactttag tcccatctga caatcgaata tctactttgc tggcgccatt tataacgtga
    16321 ttgttggtga cgatgtaagc ttctttatca ttctttttat aaataactcc agatccttca
    16381 ctagagattc gctgagaatc tgtgtcagta tcatcattgc caaatacgct attttgtctg
    16441 tttgccgaat aagtaataac agaaacaaca gcatctttta ctttgttaac agcctgtgtt
    16501 gttgaatttt cgttcttata ggcagtttgt gtaatagtac tattgttgtt agagttgttt
    16561 acactacttt tttgagttag ttgagttatt gaaaaactac ccaaggctcc actaaaaaag
    16621 ctaatgacga taacgactaa taattgaaac cattttttgt aaaatgtttt tagatgtttc
    16681 atatttgcct ccatatgttt gaattactga aagtataaac tgactagctt aattataact
    16741 taaacacaaa agttttacac aaactgtgga taactctttt gaaactgtga ttttcttaat
    16801 tgaaatctat tttttatttt gtgaataaga tgtgaaaaaa tagagaatat gttagaatag
    16861 agtcatgaaa attaaagttg taacagttgg gaaactgaaa gaaaagtatt taaaagatgg
    16921 tatcgcagag tattcaaaac gaatttctag atttgctaag tttgaaatga ttgagttatc
    16981 agatgaaaaa acaccagata aggccagtga atcagaaaat caaaagattt tagaaataga
    17041 aggtcagaga attttatcaa aaattgctga ccgtgatttc gttattgtgt tagccattga
    17101 agggaaaact ttcttctcag aagaatttag taagcagtta gaagaaactt ctataaaagg
    17161 attttctact cttactttta ttattggggg aagtttagga ttgtcatcat ctgtaaaaaa
    17221 tagagccaat ctttctgtca gttttggtcg cctaacctta cctcatcagt taatgagact
    17281 agttcttgtt gaacaaatct atcgcgcttt tacgattcag cagggattcc cctaccataa
    17341 atagaaaatt gacttttaat tgaatttttg gtagaataat tgtgttaggt ctcatagctc
    17401 agctggatag agcattcgcc ttctaagcga acggtcgcag gttcgaatcc tgctgggatc
    17461 aatataatag caaagctggg aattttcccg gcttttttct taaaaaagta cactttggga
    17521 gaaaaaaatg acagttgaga gaattttatc taaaacgaaa ttccattttg tataatggtt
    17581 tttgtaagtt agcttacaag aaaaaaacat tttaggagat tttattatga aaaacacagt
    17641 taaattggaa cagtttgtag ctttgaagga aaaagactta caaaagatta aaggtgggga
    17701 gatgaggctg tcaaaattct tccgtgattt tattttacaa agaaaaaagt aatgaaataa
    17761 ggggaaagag taatggattt atttggattt gggacagtta ttgttcatct tttaattatt
    17821 agtcacaact accatttaat ttgtaaaggt caaataaata gaaaagaatt attcgttttt
    17881 ggtgcttata cattactaac agaaatagta tttgattttc ccttatatat tctatattta
    17941 gatgggttag ggattgcaat atttttattt cctttgggct tatattccta ttttcgatgg
    18001 atgaaacagt atgagaggga tagaggacta ttcctaagtt tactactatc tcttttatat
    18061 gagagcactc ataactttct gtccgtaact ttctcctcta taacaggaga taattttgtt
    18121 ttacaatatc atttcccatt ctttttcgtt gtgacggtgt taacctattt tgttacatta
    18181 aaaatcattt attatttcca tttggaacta gcctattttg acaaggacta cctttatcct
    18241 ttcttgaaaa aagtattttt tgctttacta ttgctacata ttgtatcttt cgtttcagat
    18301 atggtaagta cgattaaaca tttgaatagt tttggaagta ttttgtcatc tattgtcttt
    18361 atctctctcc ttttgacctt ctttgcaatg aattctcata aagttcaaat ggagaaagag
    18421 attgctttga agcagaagaa atttgaacag aaacatttac agaattacac agatgaaatt
    18481 gtcggtctgt ataatgaaat ccgtggtttt cgacatgatt atgctgggat gcttgtcagc
    18541 atgcagatgg caattgacag tggtaattta caggaaattg acagaattta caatgaagtt
    18601 ttagtcaaag caaatcataa attgcgttca gataagtaca cttactttga tttgaacaac
    18661 atagaagact cagctttacg aagtttggtt gctcagtcaa ttgtctatgc tcgaaataat
    18721 ggtgtagagt ttacactgga agtaaaagat acgattacca agcttccaat tgaactattg
    18781 gatttggttc gtatcatgag cgttttattg aataatgctg tcgaaggatc ggctgatagc
    18841 tataaaaagc agatggaagt agcagttatt aagatggaaa ctgaaacagt tattgtgatt
    18901 cagaattcat gtaaaatgac gatgactcct tcaggagatc tattttcctt aggattctcc
    18961 actaagggaa gaaatcgcgg agtcggatta aataatgtga aagaactact agataagtac
    19021 aacaatatta ttttagaaac agagatggaa ggcagtacat ttagacaaat cattagattt
    19081 aagagggaat ttgaatgaaa gttttaattt tagaagatgt tattgaacat caagtgagac
    19141 tagagagaat attggatgaa atttcgaaag aatcgaatat tccaatatca tacaagacaa
    19201 cgggaaaagt ccgtgaattt gaagaataca ttgaaaatga tgaagtaaat cagctttatt
    19261 tcctagatat cgatattcat ggaattgaga aaaagggatt tgaagtggct cagttcattc
    19321 gtcattacaa tccttacgct attatcgtct ttatcactag tcgatcagag tttgcgactc
    19381 taacctataa ataccaggta tcagccctag attttgttga taaggatatc aatgatgaga
    19441 tgtttaagaa gagaattgag caaaatatct tctacacgaa gagtatgtta cttgaaaatg
    19501 aagatgttgt agattatttc gactacaatt acaagggaaa tgatttaaaa attccttacc
    19561 atgatatttt gtatattgaa acaacagggg tatctcataa attgcgcatt attggtaaga
    19621 attttgcaaa agagttttat ggtaccatga cagatattca ggaaaaggac aaacatactc
    19681 agcgatttta ttctcctcac aagtcatttt tggtaaatat aggcaatatc agagaaattg
    19741 atcgaaaaaa cttagaaatt gttttctatg aagaccatcg ttgtcctatt tcaagattaa
    19801 aaattagaaa attaaaagat attttagaga aaaaatctca aaagtgattg acaattagca
    19861 agaaattgat ataatggtta tatctgctac agatagaagg tccgttggtc aaggggttaa
    19921 gacaccgcct tttcacggcg gtaacacggg ttcgaatccc gtacggacta ttttatccgc
    19981 catagctcag ttggtagtag cgcatgactg ttaatcatga tgtcgtaggt tcgagtccta
    20041 ctggcggagt atagataaaa gggaacacag ctgtgttcct ctttttgtat caatttgtat
    20101 caccaagcat tttcataagg aagtctgtta tttcttgaga actttctttt tttccatgtg
    20161 caatccaagt ttggcagaca ccaaaaagtg catgagttag atagatgcta ctatattcta
    20221 attcagtggt atttagattc agttgcataa atcgcttttg taaatctgta ctgagcatga
    20281 tatgaagttt atttcgtaag aaattttgga tttctttagt cccattttca gaaagaaggg
    20341 cagccagaag tggttctgac tctagatatt caaaaacttc taaaatagcg tctcttttgt
    20401 gatgagcatg tttttgaaaa atatattcaa atgtatggaa tagcttgctt tgatagtgct
    20461 caatcatatc atacttatcc ttatagtgag tatagaagct ggaacgacta attccggctt
    20521 tttctactaa tttgacagta gaaattttat caaatggctg ttccatcagt aattgtacca
    20581 tagcgttttc aatagttcgc tttgttttta agcgtttgtt actttcttgc atatttcctc
    20641 cttgtaaaca aattagacta tatgtctaaa aatagatttt ttatcttgta atttagattt
    20701 tttaatgtat aatctattat atcaaaattt tagacaatat gtttaaaaaa ggagaaacta
    20761 tgtttaaaga atggaaagca atttaaaaaa aaacaacctt tattattgtc atgatcggga
    20821 tttctcttat tccagctctg tacaatatca tatttttgtc atcaatgtgg gagccatatg
    20881 ggcaattgtc tgacttacct gtggcagttg taaataatga taaagaggct tcctataatg
    20941 gtaatactat ggcaatagga aaagacatgg tgtccaattt aaaagaaaat aaaaccttgg
    21001 attttcattt tgtagatgaa gaggaaggaa agaagggatt ggaagatggc gattactata
    21061 tggtagtgac tttaccaagt gatttatctg aaaaaacaac tacattatcc aatattcaat
    21121 cgacagcagc ttatcaatca ttgacaagtg agcaacaaac tgagataagt gattctgtat
    21181 ctcaaaattc aactgatagt attcaatcgg ctcagtcaat tgtagcttta gtacaaggtt
    21241 tacagggaag tttagaaaac ttacaaaatc aatcttctaa tctttcgact ttaaaaaatc
    21301 aagctaatca agtattacct attacttcta cttctttgat aggattgtca agtggattaa
    21361 cagagataca aggagatgtt actagcaaat tagttcctgc cagtcagtcg attgcatcag
    21421 gtgtaaacgc atatactaca ggtgttgata aagtttctca gggcgcaagt caactaagtg
    21481 aaaaaaatgc caccttgaca ggtagtttgg ataaactagt ttcaggctca aacaccttga
    21541 cacaaaaatc ttctagattg acagcaggag ttggttaatt acaatcagga tctgggcaat
    21601 tagcagacaa atccagtcag ttactttcag gtgcttctcc attagagaat agagctaata
    21661 aattggcaga tggatctagg aaactagcag aaggtggaac aaagttaact tctggattgg
    21721 aagatttaca gacaggactt gcttctttag gacaaggact aggtaatgct agtgatcaac
    21781 tcaaatcagt atcaacagaa tctaaaaatg cagagatttt gtcaaatcca ctcaatcttt
    21841 caaaaacaga caatgatcaa gttcctgtaa atggaatcgc aatagctcct tatatgatat
    21901 cagttgctct tttttttgca gcaatatcaa caaatatgat atttgcgaaa ttgccttcag
    21961 gacgtcatcc agagagccgt tgggcttggt tgaaatcttg agctgaaata aatggtatta
    22021 tagctgtttt ggcaggaatt ttggtatatg gaggagttca gcttattggt ttaactgcta
    22081 atcatgagat gagaatattt attctcatca tcctaacaag tttagtattc atgtctatgg
    22141 tgaccacttt agcaacgtgg aatagccgta taggagcttt tttctcactt attttgcttt
    22201 tactacagtt agcatcaagt gcaggtactt atccacttgc tttgacaaat gatttcttta
    22261 gatctattaa tccctggtta ccaatgagct attcagtttc gggattacga caaacaatct
    22321 ctatcaacaa gtcattttcc tagctgtcat actagctcta tttactggtt taggtatgct
    22381 agcctatcaa cataagaaaa tggaagaaga ttaaaaaaat cgaccgatta actggtcgat
    22441 tttttatgcc ttagatgact ttcgtctgtg attatagatt ccaaatagta agagagaagt
    22501 aaaggaacag attgctccag taataaaacc attgggaatg aaggaaagtg taatagttcc
    22561 tttccccttg ggaatgtcaa ctttcataaa tccagtttga gcttgtttaa tttctatttt
    22621 cttaccatct tggtaggcag accaaccttt gtcataagga atggtgaaga aaatagatgt
    22681 atcttgttgg acatcatatg tagcaaaaac cttgttttta gaagttgata ctgtgacagg
    22741 ttgttcttta attttttgaa ttgcctcggt gaaagttttg gtatctaaac gatagaaggt
    22801 aggagattca aatgatactt gtgaatttcc agggaaacta acattgatat tgaaagtttt
    22861 tttctcttta gtatatccta gattaaagaa ggagaagaca ttatcagttg taaaagtctt
    22921 tttttcacca tttacaagga tgtcaacctt cttttgttta tcgttagaaa agtgaaggtt
    22981 tatgaaagag agataaactt ggctgttttc tggaacttca atttgatact ggattgctgc
    23041 atcttcattt gaagaacttg tgacactaat caaatcatta gtattttcta ttttttctgt
    23101 tttttcataa ggtattggag aaaaataatc aaaattgacg ttagcaagtt gatttaaaaa
    23161 tgaggcctga ttatccaagg tatgttcatt gaacttgaca tcattgtaaa cagattgact
    23221 agcaactgca atcggaagag agtattgatt ttcatatagg gtaagattat ctttttgata
    23281 gatatcttta aagccatact tatcaatagg actgtctgag atattgtact ggataccaaa
    23341 taaactatca gccaaaatac tattatttgc atatcggaga ttgagattag tcccagagga
    23401 tttaaaacca agtttatcta aagtagagct tgatgaacga tttcgaacag atgaaaattg
    23461 agagattcca ttgtagttga atttcatact gtcatttcct gtctgagttt gtagtttttc
    23521 agtacgagta aattgatttc caatatatgt tgagaaagat tccatagctg ggatatctcg
    23581 actataagca cttcgagaag caaatcccca ttccttagca attccgtcca tttgagatga
    23641 agcatttaaa ctcatttcaa ccagtataaa taaagagatt agaatggcaa atagattcac
    23701 agatataaac tttttgataa ctgcaaggag taaaagagaa tagacaacca aaaattcaag
    23761 agtaagcaga atattcaaat ctgttaaaaa agaataatgc gattttagat agatggtagc
    23821 taaaaatcct gctactacaa gaaaaagcga aactaaaaaa ttccagactt taagttcttt
    23881 cagacgattt aagacttctg ctgctgtgta aattaacaag gtagagaaaa tccaagcata
    23941 gcgatgtaaa aacatgtttg gagtatgcat gccttgccaa aataagtcaa gagcttctat
    24001 gtaaaagctt gcaattagaa atgcaaagaa tattacatat atgagtttca cgtgaaactt
    24061 aatagatttc agcgtaaaaa ataaaatggt caaaataaag ggaagtagtc caacaaaaat
    24121 cattgggatg gccccatact ttgttgtgtc aaaggaacca atgaattgct tagcaaagag
    24181 atcaagatac cagctacttt cagtttgaaa ctttgtaact tcagtcaatt tttccccatg
    24241 tgtctgtaaa tcaaacagag tgggaagagt cataatcaaa ctagccatac cagctaaaaa
    24301 ggagataact atgaaatcaa gaacagatga ttttcgagtc ttaaagtccc acgaaatttg
    24361 acagagatac cagaaaataa gaaacaatac tgtcatatat ccaaaataat aattttgaat
    24421 aaataagatt gacagacttg taaagtacaa taggagtttc ttttcagtta tcagtagatg
    24481 taaaccagtt ataattaaag gaatcaagat aaaaacatct agccaggttt ttatctctaa
    24541 ttgactgaca gtgaaactca tcagagcata ggaagtagat aaggctagtt ttaaaatctg
    24601 agggatagat tgaaacaatt tattcaaact aaaaaaggtt gacagaccaa tcaatccaaa
    24661 ttttaagaga gttgtcagat agatagcatc tggcatattc gttagatcaa aaaagtaaac
    24721 cagaggcgcg agaaaactac ccaagtaata actagatagg gcatagaagt ttagccctag
    24781 accacttgta aaggtgtaaa acagattact atttccatgt aggatatttc gtaaggctac
    24841 atcaaaaata acgtattgat gaaagccatc tcctaataga ggagagttgt cgctattcca
    24901 gtagatacct tgagatagat atactccaga cataatcact acaggaatga tgaaagaaat
    24961 aaaataggtt cgatatgttt ttaaaaatga tttcatgtta cctcgtagaa tgatagaaaa
    25021 ctcagttggt taacccaact gagttttgaa gttttattta gtctttccaa agttctttaa
    25081 cttttgcttg tatttctgca ttttctagga attcatcgta ggtttcatcg atacggtcaa
    25141 tgacgccatt tttagataag acaatgatat ggttagccaa agtttgaata aattcgtggt
    25201 catggctggc aaagatgatt gattctttaa agtttttcaa tccatcattc aagcttgaga
    25261 tagattccaa gtccaagtga tttgttggat catcaagtac aaggacattt gattttaaga
    25321 gcatgagttt tgaaagcatg acacgaactt tttctccccc tgacaagaca tttacaggtt
    25381 tgttaacttc atctccagag aagagcatac ggccgaggaa gccacgtagg aaagtattgt
    25441 catcttcttc tttacttgcg aattgacgca accagtcaag aattgattct cctcctgcaa
    25501 aatcagctga gttatctttt ggtaggtaag attgactagt tgtaactccc cacttgacag
    25561 ttccttcata gtcaatatct cccatgattg cacgaattaa tgcagtcgtt tgaatatcat
    25621 tttgtccaat aagtgctgtc ttatcatctg gacgcaagat gaaactaata ttatccaaga
    25681 tagtttcacc atcaatcttt acagttaaat tttctactgt caagagatca ttaccaatct
    25741 cacgttccgc tttaaagttg ataaatggat atttacgact agatggcaca atctcttcta
    25801 gctcaatctt atcaagcatt ttcttacgtg atgttgcctg ccttgactta gaagcattgg
    25861 cagagaaacg agcaacaaat tcttgcaatt gtttaatttt ttcttctgct ttagcattac
    25921 ggtctgctag caatttagca gcaagctcag aagattcctt ccagaagtcg tagtttccga
    25981 catagagttt gatttttcca aagtcaaggt cggccatgtg agtacaaact ttgtttaaga
    26041 agtgacggtc gtgggatact acgataactg tgttatcaaa gtcaatcaag aagtcttcta
    26101 accaagtaat cgattggata tccaaaccgt tagtaggctc gtccaagaga agaacatctg
    26161 gtttaccaaa aagtgctttg gcgaggagaa cctttacttt ttcaccgttg gccaattcgc
    26221 tcatgttttg gtagtgtaat tcttctggaa tgtttaggtt ttgaagtagt tgagaggctt
    26281 cactctctgc ttcccaacct ccaagttcgg caaactctcc ttcgagttcg gcagcacgaa
    26341 ccccgtcctc gtctgagaaa tcttccttca tgtagatagc atctttctct ttcatgatgc
    26401 tataaagttt ttcatttccc atgataacga catcaatggc acgttcatct tcgtagtcaa
    26461 agtgattttg acgaagaaca gagagacgtt catctggacc aagagagatg tgaccagtag
    26521 taggttcgat atctccagct aaaattttta aaaaggttga ttttccggca ccattagcac
    26581 cgattaatcc gtaagtattt ccttctgtaa atttgatatt gacatcatca aaaagtttgc
    26641 gatcactaaa acgtagtgaa acatcagata ctgtaagcaa tgtttttctc ctatatgtgt
    26701 aatatattta ttctactaga aaatacagaa atattcaaat ttttatttgt caattttgtg
    26761 taaattatat ttacagtatc ctttacacaa atctgtaaaa agcaaggctg atttattttg
    26821 ataaattacg gttatttcat taaaaaaatg ctataattga aaggactata tcgaaggaga
    26881 acaaaatgac taaacccatt attttaacag gagaccgtcc aacaggaaaa ttgcatattg
    26941 gacattatgt tggaagtctc aaaaatcgag tattattaca ggaagaggat aagtatgata
    27001 tgtttgtgtt cttggctgac caacaagcct tgacagatca tgccaaagat cctcaaacca
    27061 ttgtagagtc tatcggaaat gtggctttgg attatcttgc agttggattg gatccaaata
    27121 agtcaactat ttttattcaa agccagattc cagagttggc tgagttgtct atgtattata
    27181 tgaatctagt ttcgttagca cgtttggagc gaaatccaac agtcaagaca gagatttctc
    27241 agaaaggatt tggagaaagc attccgacag gattcttggt ctatccaatc gctcaagcag
    27301 ctgatatcac agctttcaag gctaattatg ttcctgttgg gacagatcag aaaccaatga
    27361 ttgagcaaac tcgtgaaatt gttcgttctt ttaacaatgc atataactgt gatgtcttgg
    27421 tagagccgga aggtatttat ccagaaaatg agagagcagg gcgtttgcct ggtttagatg
    27481 gaaatgctaa aatgtctaaa tcactaaata atggtattta tttagctgat gatgcggata
    27541 ctttgcgtaa aaaagtaatg agtatgtata cagatccaga tcatatccgc gttgaggatc
    27601 caggtaagat tgagggaaat atggttttcc attatctaga tgtttttggt cgtccagaag
    27661 atgctcaaga aattgctgat atgaaagaac gttatcaacg aggtggtctt ggtgatgtga
    27721 agaccaagcg ttatctactt gaaatattag aacgtgaact gggtcctatt cgtgagcgcc
    27781 gtattgaatt tgctaaggat atgggagaag tttataatat gattcaaaaa ggtagtgaaa
    27841 gagcgcgtga agttgcgggt caaaccctat ctgaggtaaa aggggcaatg ggacttcatt
    27901 actttaacta agtttatttt acaagaaact atcttttcta tctcgaagaa aagatagttt
    27961 tttatttacc cctgtaacat ttgacaaatt tttatagaat ggtatgatag atacaatata
    28021 aaaagagtca agctcaaaaa gaaagaaaag aggaaacttc gaatgtctaa ttgggacact
    28081 aaatttttga aaaaaggttt tacctttgat gatgtattgc ttattccagc tgaaagtcat
    28141 gtgttgccta acgatgcaga tttaacaact aaattggcag ataatttgac tttaaatatc
    28201 ccaattatta ccgctgccat ggacacagtt acagagagtc aaatggccat tgctattgct
    28261 cgtgcaggcg gtctcggagt tatccataaa aacatgtcaa ttgctcaaca agcagacgag
    28321 gttcgtaagg taaaacgttc tgaaaatgga gttattattg atccgttctt cttgacgcct
    28381 gaacatacaa ttgctgaagc agatgagctt atgggtcgtt accgcatcag tggtgttcca
    28441 gttgttgaaa cacttgaaaa tcgtaaattg gttggtattt tgacaaaccg agatcttcgt
    28501 tttatttcag attataatca accaatttca aaccatatga ctagtgaaaa tcttgttact
    28561 gctcctgtgg gtacggatct tgcaacggct gagagtattc ttcaagagca tcgtattgaa
    28621 aaacttccgt tggtcgatga agaaggcagt ctttctggtt tgatcactat caaagatatt
    28681 gaaaaagtta ttgagtttcc aaatgcagct aaagatgagt ttggtcgtct tctagttgca
    28741 ggtgcagtag gtgttacttc agatacattt gaacgtgcag aggctctttt tgaggcagga
    28801 gcggatgcga ttgttattga tactgcacat ggtcattctg caggtgtctt gcgtaaaatt
    28861 gccgagattc gtgctcattt cccagatcgg actttgattg ctggaaatat tgctactgct
    28921 gaaggtgcac gtgcccttta tgaagcgggt gtagacgttg ttaaggttgg tattggacca
    28981 ggttctatct gtactactcg tgtgattgct ggtgttggtg ttccgcaagt aacagctatc
    29041 tacgatgctg cagctgttgc gcgcgaatat ggtaaaacga ttattgctga cggtgggatc
    29101 aagtattctg gagatattgt aaaagcactt gctgcaggtg gaaatgctgt tatgcttgga
    29161 tctatgtttg ctggaactga tgaagctcca ggcgaaactg aaatcttcca aggacgtaaa
    29221 ttcaagactt accgtggtat gggatcaatt gctgctatga agaaaggttc aagcgaccgt
    29281 tatttccaag gttctgtcaa tgaagcaaac aagcttgttc cagaaggaat tgaaggtcgt
    29341 gttgcttata aaggagcggc agctgatatt gttttccaaa tgattggtgg tattcgctct
    29401 ggtatgggtt actgtggtgc agctaacctt aaagaactac acgataatgc tcaatttatt
    29461 gaaatgtctg gtgctggttt gaaagaaagc catcctcatg atgtgcaaat tactaatgag
    29521 gcaccaaatt attctatgta aaaaacaatg aaaagaactc cagtgaaaac aggagttctt
    29581 ttacaatgtt gtcaatttcc atttacagca gctttaccat cctgaatagt gaagatactt
    29641 agattttctg gcagattttg aagatggtct aagcttgttg ttgtgataaa ggtttggatt
    29701 gattgagaaa tcgtttctaa taattttaac tgtctagtgt tgtcaagttc actcatcaca
    29761 tcgtcaagca gtaatatagg agattctgtg gtaatgcttt ccattaattc gatttctgct
    29821 aattttatcg agaggacgag actacgatgt tgaccttggc ttccgaaact agcatccatc
    29881 ccatttatat aaaaagaaat gtcatctcga tgaggaccga caccagtatt ctttttaaat
    29941 aaatctctgg atctactttt ttctaaagca attttgaaag attcggataa gttttgtttg
    30001 tcagttatat tgacagaaga ttgataggat attgacaact cttcgatctg attagagagt
    30061 tcaaaatgtt tcttacgccc aaatgattct agttttttta tgaaatctaa gcggtgattc
    30121 attacacgac atccataatc aactagctga tcatctaaca cagaaaggaa tgtttcatct
    30181 attttttgag ctgattttag gtaagtgttt ctttgcttta ggatgtggtt ataattggtt
    30241 aagtcagata aatagattgg cttaatttgc ccaagttcca tatcaatgaa ttttcgtcga
    30301 atcgaaggtg ctcctttaat tagttgtaaa tcttcaggag caaataagac aacattcatg
    30361 tgtcctacat aatctgaaag gcgtgcctgt tttaagtgat taacttttgt tacacgacct
    30421 ttttgtgtta gttcgatttc taggggaatg gatccagttt ttttctgaac gagacctgaa
    30481 agatgaagtt gttcctcatc aaaatgaatg agatttttat ctgttcgagt tcgatgacta
    30541 cgcgttaagg ctaaaaaata gatagcctct aacatgtttg tttttccttg tgcattacgt
    30601 cccaaaaaga cattcaattt aggattaaag tctattttcg tttctttgta attacgaaaa
    30661 gtcttgagag atagatgttg tagccacatg attatctacc agggaatcgt ggagcttgtt
    30721 ggcttttagg tgatgaagca ggtttcgatt tgtctttttt aactccctta ttcatctttt
    30781 tgacaagttt agcgatccgt tctttttcaa ctttatcagc ttggtattca tcttgttctt
    30841 cagaagtagg ttgtgtcaac aagatgtcaa tgttcatgtc agggatgtca actttatcgc
    30901 caatacgaag tttttttcca cgacggctct ctaattccct attaaagtaa acagaatgtt
    30961 cagagagaaa tgatttaata gctcctccgc tatgtgtaat tccaagttct ttgagtagtg
    31021 cttggagggt aataaattct tcaaataatt tgtattccat aattcacctc aatctttggt
    31081 attataccat attttcctaa aaatagtgag agagacagcg agaaatgtaa gcgattttta
    31141 tttcaaaagt gttacaggga acaagaaaat ttcaggtttt cgtgatataa tagaagtctg
    31201 tatataagga ggtaaatcat ggagttagtg catggaattt caacacattt tatccaatca
    31261 aaaaagttta aaacaaacaa aattaccgtg cgttttaccg ctccattatc ccttgatacg
    31321 attgcaggtc acatgttgag tgcaagtatg ctagagactg ctaatcagat gtaccccact
    31381 tctcaagatt tgaggagaca cttggccagt ctatacggta cagatatgtc aaccaattgt
    31441 ttcagaagag ggcaaagcca cattatagaa ttgacattta cctatgttcg tgatgagttt
    31501 ttaagtagga aaaacgtgct aacctctcag attttggaac ttgtaaaaga aactcttttt
    31561 tcacccgtag tagttgataa tgggtttgat ccggccttat ttgaaattga gaaaaaacaa
    31621 ttgctagcaa gtttagcagc tgatatggat gattcttttt attttgcaca taaagaattg
    31681 gataaattgt tttttcatga tgaacgtctt caattggaat atagtgattt acgaaatcgt
    31741 attttagctg aaactccaca aagttcttat tcttgtttcc aagaattttt agccaatgat
    31801 cgaatagatt tctttttcct aggtgatttt aatgaggttg aaattcaaaa tgtattagaa
    31861 tcatttggct ttaaaggtcg aaaaggagat gtgaaggttc agtattgtca accttattct
    31921 aatatccttc aggaaggtat ggttcggaaa aatgtgggac aatccatttt ggaattaggt
    31981 tatcattacc gttctaaata tggtgatgaa caacatttac ccatgattgt aatgaatggt
    32041 ttacttggtg gatttgctca ctctaagctc tttacaaatg tccgtgaaaa tgctggatta
    32101 gcttatacca tttcaagtga gcttgattta tttagtggat tcttgaggat gtatgctggt
    32161 atcaatcgag aaaatcgtaa ccaggctcgt aaaatgatga ataatcaact gcttgattta
    32221 aaaaaaggtt attttacaga gtttgagtta aatcagacca aggaaatgat tcgttggtcg
    32281 ttgttacttt ctcaagataa tcaatcttca ttgattgaac gtgcttatca aaatgcctta
    32341 tttggaaaat cttcagcaga ctttaaaagt tggattgcaa agcttgaaca aattgacaaa
    32401 gatgctattt gtagagtagc taataatgtg aaactacaag cgatttactt tatggaagga
    32461 atagaatgac aaaggttgtt tttgaagaaa aatactatcc agctgtaaaa gaaatggttt
    32521 atcgaactcg tttggccaac ggattgacag ttgctctttt gcctaaaaag gaatttaaag
    32581 aggtttacgg gagtgtcact gtacagtttg gttcggtaga tacgtttgtc acagaagttg
    32641 acggagatgt aaaacaatat cctggaggaa ttgctcattt tcttgaacat aaattatttg
    32701 agagagaaga ttctagtgat ttgatgtcgg cttttacgag tctaggtgca gatagtaatg
    32761 cctttacaag ctttacaaaa acaaactatc ttttttcagc aacggattat tttttagaaa
    32821 atttagattt acttgatgaa ttggtaacat cagcacactt tactgaagct tccattctga
    32881 cagagcagga tattattcag caagaacgag aaatgtacca agatgatcca gattcgtgtt
    32941 tattcttttc aactttagcg aatttgtatc ctggtacacc tttagcaact gatatagttg
    33001 gaagtgagga gtccatttcc caaatcaatc taactaattt gcaagaaaat tttacaaagt
    33061 tttacaaacc tgtaaacatg tctctgtttt tagttggtaa ttttgatgtg gagcgagtac
    33121 aggactattt tgaaagcaaa gaactgaaag attcagattt tcaggaagta gcaagagaaa
    33181 agttgttttt acagcctgta aagccaacag atagtatgag aatggaagta tcttctccca
    33241 aactagcgat tggagttaga ggtaagcgag aagtttctga agcggattgc tatcgacatc
    33301 atattttatt aaaattattg tttgcaatga tgtttggttg gacttcggat cgttttcaaa
    33361 aatgttatga atcaggtaaa attgatgcgt ccttatctct ggaagttgaa ataacaagtc
    33421 gctttcattt tgtcatgttg acaatggata cgaaagagcc agttgctttg tctcatcaat
    33481 ttaggaaggc tattcgtaat tttacaaagg atttagatat tacagaggaa catttagata
    33541 ttatcaaaag agagatgttt ggcgaatttt tcagtagcat gaactctctt gaatttattg
    33601 caacgcaata tgatgctttt gaaaatggtg agacaatttt tgatttgccg aaaattttac
    33661 aggaaattac tttagaggat gtccttgatg ctggacatca tttaatagat gatggtgaca
    33721 tagttgattt tacaatattc ccatcgtagt aacctattat aatagacact agaaagaagg
    33781 gatgacaagt atgagaaaaa aaacaattgg agaggtttta cgattagcta gaatcaatca
    33841 gggattgagt ttagatgaat tgcagaaaaa gacagaaatc cagttagata tgttggaagc
    33901 aatggaagca gacgatttcg atcaacttcc aagtcctttt tacacgcgtt ctttcttgaa
    33961 aaaatatgca tgggctgttg agttagatga ccaaattgtt ttggatgctt atgattctgg
    34021 gagtatgatt acttatgagg aagtagatgt tgatgaagat gagttgacag gtcgtagacg
    34081 ttcaagtaag aaaaagaaga aaaaaatatc atttttacct ttattttatt ttatcctttt
    34141 tgctttatcg attttaattt ttgtgactta ttatgtttgg aactatattc aaactcaacc
    34201 agaggagcct tctctttcta attacagtgt ggttcaatca acaagttcaa ctagctctgt
    34261 tccccactcc tcaagtagta gttcttctag tatagaatca gctataagtg tatcaggcga
    34321 aggaaatcat gtagaaatcg cttataagac aagtaaggaa acagttaaat tgcaattggc
    34381 agtttcagat gttacaagtt gggtcagtgt ttcagaaagc gaacttgagg gcggtgtaac
    34441 cttatcgcca aagaagaaaa gtgcagaagc aacagttgca actaaaagtc ctgtaacaat
    34501 tacgttaggt gttgtaaaag gtgttgattt gacagtagat aatcagactg ttgatttatc
    34561 gaaattaaca gctcagactg gacaaatcac tgtaaccttt actaaaaatt aaggaaaaac
    34621 gaatgaaaaa agaacaaatt cccaatctct taacaatagg tcgaattctc tttataccta
    34681 tttttatctt tattttaacg ataggaaatt cgatagagag tcatatagtt gcagctatta
    34741 tctttgctgt tgccagtatt accgactatt tagatggata tttagctcgt aaatggaatg
    34801 tggtcagtaa ttttggtaaa tttgcagatc ctatggcgga taagttacta gttatgtcgg
    34861 cttttattat gttgattgag ttaggtatgg ctccggcttg gattgttgca gtgattatct
    34921 gtcgtgagtt agctgtgaca ggtttaaggc ttttattggt tgaaactggt ggaacaattt
    34981 tagcagcagc aatgcctgga aaaattaaaa cttttagtca gatgtttgcc attattttct
    35041 tgctattaca ttggactttg cttggtcaag ttctacttta tgtagcctta tttttcacta
    35101 tctactctgg ctatgactat ttcaagggta gtgcctatgt atttaaaggg acatttggtt
    35161 cgaaatgaaa tcaataattg atgtaaaaaa tctttctttt cgctataaag aaaatcagaa
    35221 ctactacgat gtgaaggata ttacgtttca cgtgaaacgt ggagaatggc tttcgattgt
    35281 agggcataat ggtagtggta aatcaacgac ggttcgatta attgatggct tactggaagc
    35341 agaatccgga gagattgtaa ttgatggcca acgtttgact gaggaaaatg tttggaatat
    35401 acgtcgtcaa atcggtatgg tttttcaaaa tccagacaat caatttgttg gagcgactgt
    35461 tgaagatgat gttgcttttg gtttggaaaa tcagggactt tctcgtcaag aaatgaaaaa
    35521 gagagtggaa gaagctctgg ctttagttgg catgttggac tttaaaaaga gagagccagc
    35581 gcgtctatca ggtggccaaa agcaacgtgt ggccattgca ggtgttgtag ccctaagacc
    35641 agctatttta atcttagatg aagcaacgag tatgttggat cctgaggggc gtagagaact
    35701 tattgggaca gtaaaaggaa ttcgaaaaga ctatgatatg acggtcattt ctattaccca
    35761 tgatttggaa gaagtcgcca tgagtgatcg cgtattggtc atgaaaaaag gggaaattga
    35821 atcaactagt agtccaaggg agcttttctc tcgaaatgat ttagatcaaa ttggattaga
    35881 cgatcctttt gctaatcaat taaaaaaatc tttgagccag aatggctatg atttacctga
    35941 aaattatttg acagaaagtg agctagagga taagctatgg gaattgctct agaaaatgtg
    36001 aattttacat atcaagaagg tactccctta gcttcagcag ctttgtcgga tgtttctttg
    36061 acgattgaag atggctctta tacagcttta attgggcaca caggtagtgg taaatcaact
    36121 attttacaac tcttaaatgg tttattggtg ccaagtcaag ggagtgtgag ggtttttgat
    36181 accttaatca cctcgacttc taaaaataaa gatattcgtc aaattagaaa acaggttggc
    36241 ttggtatttc agtttgctga aaatcagatt tttgaagaaa cggttttgaa ggacgttgct
    36301 tttggaccgc aaaattttgg agtttctgaa gaagatgctg tgaagactgc gcgtgagaaa
    36361 ctggctctgg ttggaattga tgaatcactt tttgatcgta gtccgtttga gctgtcaggg
    36421 ggacaaatga gacgtgttgc cattgcaggc atacttgcca tggagccagc tatattagtc
    36481 ttagatgagc caacagctgg tctagatcct ctagggagaa aagagttgat gaccctgttc
    36541 aaaaaactcc accagtcagg gatgaccatc gtcttggtaa cgcatttgat ggatgatgtt
    36601 gctgaatatg cgaatcaagt ctatgtaatg gaaaagggac gtttagtaaa ggggggcaaa
    36661 ccaagtgatg tctttcaaga cgttgttttt atggaagaag ttcagttggg agtacctaaa
    36721 attacggcct tttgtaaacg attggctgat agaggcgtgt catttaaacg attaccgatt
    36781 aagatagagg agttcaagga gtcgctaaat ggatagtatg attttagggc gttatatccc
    36841 aggggattcg attgttcacc gattggatcc acgtagcaaa ttgcttgcta tgatgctact
    36901 gattttgatt gtgttttggg ctaataaccc cttgacgaat ctgattcttt ttatagcgac
    36961 agggatattt attgccttgt caggagtatc tctttcattt tttattcagg gcttgaagtc
    37021 tatgtttttc ttgattgcct tcacaactat ttttcaacta tttttcattt ctaatgggaa
    37081 tgttttattt gagttttcgt ttgtgagaat cacggattat gctttgcaac aagctgggat
    37141 tattttttgt cgctttgtat tgattatttt cttttcaact ttgttaacct taacaaccat
    37201 gcctttaagt ttggcatcag ctgtcgaagc tttattagca cctttaaagc gtgtgaaagt
    37261 tccagttcat gaaattggat tgatgctgtc tatgagtttg cgttttgtcc caaccttgat
    37321 ggatgatacg actcggatta tgaatgcaca gaaagctcgt ggagtggatt ttggagaagg
    37381 aagcatcgtt caaaaagtaa aggcgatgat tcccattttg attcctcttt ttgcgacaag
    37441 tttaaaacgt gcagattcct tggctatcgc tatggaagcg cgtggctatc agggtggaaa
    37501 aggcagaagt caataccgac aattgaaatg gactctgaag gatacgctga ccattcttgt
    37561 tattctcgta cttggttgtt gtttattttt cttaaaatct tagtagcttt caggaattga
    37621 taaaaagtta ctgtaacagt ttttgatata aaggtaggaa tatgaaccgt tttaaaaaat
    37681 caaaatatgt cattattgtt tttgtcactg ttctgcttgt gtcagctctc ttagcgacga
    37741 cttattcaag tacaattgtg acaaaattag gagatggaat ctcattggtt gatagagttg
    37801 tacaaaaacc ttttcagtgg tttgattctg tcaaatcaga tttggctcat ttgacacgaa
    37861 catataatga aaatgaaagt ttgaagaaac agctttacca attagaagtt aaatcaaatg
    37921 aggtggaaag tttaaagaca gaaaatgaac aactgcgcca attgcttgat atgaagtcta
    37981 aattgcaagc cacaaagact ttagcagcag atgttattat gcgttctccg gtatcttgga
    38041 agcaggagtt gaccttagat gcaggtagat caaaaggtgc ttctgagaac atgttagcta
    38101 ttgcaaatgg tggcttgatt gggagtgttt caaaagtaga ggagaactct actatagtca
    38161 accttctgac aaatacggaa aatgctgata agatttctgt taaaattcaa catggctcta
    38221 ctacaattta tggaattatt attggctatg acaaggaaaa tgacgttctt aaaattagcc
    38281 aattaaatag taatagcgat attagtgcgg gagataaggt gactactggt ggattaggaa
    38341 actttaacgt tgctgatatt cctgttggtg aagtggttgc cacaacgcat agtacagact
    38401 atttgacacg agaagtaact gttaaattga gtgcagatac tcataatgta gatgtgatag
    38461 aattagtggg gaattcataa tgagacagtt gaagcgagtt ggagtatttt tattgcttcc
    38521 tttctttgtt ctaattgacg cccatattag ccagcttctg ggctcatttt tcccccatgt
    38581 acatttggct agtcattttc tttttctatt tctcttattt gagacgatag aagtatcaga
    38641 gtatctctac ctagtctatt gttttgttat aggcttggtt tatgatgttt actttttcca
    38701 tctaataggg attacaactc tcttatttat cttattggga gccttccttc ataaattgaa
    38761 tagtgttatt ttgttgaatc gttggacaag aatgctagct atgattgtgc tgacattcct
    38821 gtttgaaatg ggtagttatc ttttggcttt tatggtaggg ttgacagtag atagcatgtc
    38881 gatttttata gtctatagct tggtaccgac gatgatttta aattttttat ggattactgt
    38941 ttttcaattt atttttgaaa aatattatct ataagaacga catataaatg taacaaaggc
    39001 gtaatattta ttaggccttt ttttggtata ctagtattgt ctttaaaaga aggagtatct
    39061 acgtaatatg aagaaaaaaa tcttagcgtc acttttatta agtacagtaa tggtttctca
    39121 agtagctgtt ttaacaactg cgcatgcaga aacgactgat gacaaaattg ctgctcaaga
    39181 taataaaatt agtaacttaa cagcacaaca acaagaagcc caaaaacaag ttgaccaaat
    39241 tcaggagcaa gtatcagcta ttcaagctga gcagtctaac ttgcaagctg aaaatgatag
    39301 attacaagca gaatctaaga aactcgaggg tgagattaca gaactttcta aaaacattgt
    39361 ttctcgtaac caatcgttgg aaaaacaagc tcgtagtgct caaacaaatg gagccgtaac
    39421 tagctatatc aataccattg taaactcaaa atcaattaca gaagctattt cacgtgttgc
    39481 tgcaatgagt gaaatcgtat ctgcaaacaa caaaatgtta gaacaacaaa aggcagataa
    39541 aaaagctatt tctgaaaaac aagtagcaaa taatgatgct atcaatactg taattgctaa
    39601 tcaacaaaaa ttggctgatg atgctcaagc gttgactacg aaacaggcag aactaaaagc
    39661 tgctgaatta agtcttgctg ctgagaaagc gacagctgaa ggggaaaaag caagtctatt
    39721 agagcaaaaa gcagcagctg aggcagaggc tcgtgcagct gcggtagcag aagcagctta
    39781 taaagaaaaa cgagctagcc aacaacaatc agtacttgct tcagcaaaca ctaacttaac
    39841 agctcaagtg caagcagtat ctgaatctgc agcagcacct gtccgtgcaa aagttcgtcc
    39901 aacatacagt acaaacgctt caagttatcc aattggagaa tgtacatggg gagtaaaaac
    39961 attggcacct tgggctggag actactgggg taatggagca cagtgggcta caagtgcagc
    40021 agcagcaggt ttccgtacag gttcaacacc tcaagttgga gcaattgcat gttggaatga
    40081 tggtggatat ggtcacgtag cggttgttac agctgttgaa tcaacaacac gtatccaagt
    40141 atcagaatca aattatgcag gtaatcgtac aattggaaat caccgtggat ggttcaatcc
    40201 aacaacaact tctgaaggtt ttgttacata tatttatgca gattaattta cagagggact
    40261 cgaatagagc cctcttttca ggttttaccg tgacaatccc tattaaaaat tatatcaaaa
    40321 tagcttgaaa atattggaaa agtatggtaa aatgaaaatt gtcgtgtgaa cgataatact
    40381 cattcttgat gaattgtgaa gcagttgccc ttgggtcgtt ttgcgagttg aagtcaagaa
    40441 gaggaaaaaa acaaaaagga gaaatactca tggcagtaat ttcaatgaaa caacttcttg
    40501 aggctggtgt acactttggt caccaaactc gtcgctggaa tcctaagatg gctaagtaca
    40561 tctttactga acgtaacgga atccacgtta tcgacttgca acaaactgta aaatacgctg
    40621 accaagcata cgacttcatg cgtgatgcag cagctaacga tgcagttgta ttgttcgttg
    40681 gtactaagaa acaagcagct gatgcagttg ctgaagaagc agtacgttca ggtcaatact
    40741 tcatcaacca ccgttggttg ggtggaactc ttacaaactg gggaacaatc caaaaacgta
    40801 tcgctcgttt gaaagaaatt aaacgtatgg aagaagatgg aactttcgaa gttcttccta
    40861 agaaagaagt tgcacttctt aacaaacaac gtgcgcgtct tgaaaaattc ttgggcggta
    40921 tcgaagatat gcctcgtatc ccagatgtga tgtacgtagt tgacccacat aaagagcaaa
    40981 tcgctgttaa agaagctaaa aaattgggaa tcccagttgt agcgatggtt gacaccaata
    41041 ctgatccaga tgatatcgat gtaatcatcc cagctaacga tgacgctatc cgtgctgtta
    41101 aattgatcac agctaaattg gctgacgcta ttatcgaagg acgtcaaggt gaggatgcag
    41161 tagcagttga agcagaattt gcagcttcag aaactcaagc agattcaatt gaagaaatcg
    41221 ttgaagttgt agaaggtgac aacgcttaat ttatacaaat agtaattacc taggagggcg
    41281 gggcttagcc cggctctcct attttcaaaa aatataggag aattaaaatg gcagaaatta
    41341 cagctaaact tgtaaaagag ttgcgtgaaa aatctggtgc cggtgttatg gacgctaaaa
    41401 aagcgcttgt agaaacagac ggtgacatcg aaaaagcgat tgaattgctt cgtgaaaaag
    41461 gtatggctaa ggcagctaag aaagctgacc gtgttgctgc agaaggtttg actggtgttt
    41521 atgttaacgg taatgttgca gcagttattg aagtaaacgc tgaaactgac ttcgttgcaa
    41581 aaaacgctca attcgttgaa ttggtaaata ctacagctaa agtcattgct gaaggaaaac
    41641 ctgctaacaa tgaagaagct cttgctttga taatgccttc aggtgaaact cttgaagctg
    41701 catacgtatc tgcaacagca actatcggag agaaaatctc attccgtcgc tttgcattga
    41761 ttgaaaaaac agacgcacaa cactttggag cataccaaca taacggtgga cgtatcggtg
    41821 ttatttcagt tgttgaaggt ggagacgaag cacttgctaa acaattgtca atgcacatcg
    41881 cagcgatgaa accaacagtt ctttcttaca aagaattgga tgagcaattc gttaaagatg
    41941 agttggcaca attgaatcac gttatcgacc aagacaacga aagccgtgca atggttaata
    42001 aaccagctct tccacacttg aagtatggat caaaagctca attaactgat gatgttattg
    42061 ctcaagctga agctgacatc aaagctgaat tggctgcaga aggcaaacca gaaaaaatct
    42121 gggacaaaat tattccaggt aaaatggatc gcttcatgct tgataacact aaagttgacc
    42181 aagcttacac acttcttgca caagtttaca tcatggatga cagcaagaca gttgaagcat
    42241 accttgaatc agttaacgct tcggtagttg agtttgctcg ctttgaagtt ggtgaaggta
    42301 tcgagaaagc tgcaaacgac ttcgaagctg aagttgcagc tacaatggca gcagccttga
    42361 ataactaata atagaaagga agcaaattgc ttcctttttt gtatagggct tagatttttc
    42421 ctgaaattgt tttttcccca gtctcactcg attagaataa ttaaaacaaa aagccctata
    42481 ataagggcta agggcattta ggagactata cttcaaattc atagtaagcg cgttcataac
    42541 aaggtatcta tcctaattcc ccaacttcca gtatactaga taaaaaataa ttatcggagg
    42601 aaaggtattg tactatgata attcaactaa gtgatttagg tcaagttcac cttgtttgta
    42661 gcaagataga tatgaggcag ggaatagact cattagccta tgtagttaaa acccactttg
    42721 aattggatcc tttctccggt caagtctttc tcttttgtgg tggacgtaaa gaccgcttta
    42781 aagcccttta ctgggatggt caaggatttt ggctactata taaacgcttt gagaacgtca
    42841 gactgacttg gcccagtaca gaaaaggatg tcaaagctct cacacctgaa caagtagact
    42901 ggcttatgaa gggcttttct atcactccaa aaatatagta gattgaaact agaatagtac
    42961 acctctgctt ctaaaacatt gttagaaatc gatttgactg tcctgatcga tttgtcctgt
    43021 tcttatttca ttttactata aatccatcag aaagtcgtga tttctattga aatgaggact
    43081 ttctttttat actcatctgt tttcaaaaag cattctagtc catctccgat taacgatgga
    43141 ctttatcacc tccttctcca gtccttgtat aacatcttgg agttgattca tgacatcttc
    43201 caaagtttga aaggttttat tcttaaatcc acgtttacga atctctttcc acacttgttc
    43261 aatggggttc atctctggtg tgtatggagg aataaatgca aagccaatat tagtcggaat
    43321 ctttaaggta cttgatttat gccatatagc attgtccata acgagtaaaa gataatcatc
    43381 tggataagct tgtgaaatct cctattccta aagccccttt agcgcataac tttggctcag
    43441 cttctattat cgctcacacc atccatcaga agtttaatct gaaggtaccc aattatcgcc
    43501 aagaagaaga ttgggctagg atgggtttac caatcacacg taaggaaatc tctaatcggc
    43561 atatcaagac gagtcaatac tatttggagc ccctttataa cctcttgcga gagagactat
    43621 tgactcagcc cttacttcat gcggatgaaa cttcttatag ggtgctagag agtgatagtc
    43681 agctgactta ctattggact tttttgtctg ggaaagctga gaaacaaggg attacgcttt
    43741 accatcatgt cctaatcgat ttgttcatat cttatttcaa tccattataa atagtgagaa
    43801 atatctatcc tatcttctag aatgtcttcc aaacgtggaa actctcgtaa acaaagaggt
    43861 tttagaggcc tatttaccat ggactaaagt tgtacaagaa aagtgcaaat aagaaatctc
    43921 cagattagga actatccgtg agttctctag tctggagatt tttcaataga cttcgttatt
    43981 ggacggttac aattcataaa gtgctgtaga gagataacgt tcaccgttat ctggtgctag
    44041 ggcaaggact tttttacctg tacctaattt tttggcaacc tcgatggctc cgtagatagc
    44101 tgcagctgag gaaatcccta caaggaagcc ttcttttcca ccaatttcac gtccgagtgc
    44161 aagagcgtca tctgatgtta cacgaacgat accatcatag gctttagtat caagtgtatc
    44221 aggaataaat ccagctgaga taccttgaat tttgtgagga ccaggttttt caccagatag
    44281 aatagcagat tcatctgctt ctactgcaaa aacttgaatg ttagaatttt ctgatttgag
    44341 tgcatgagaa acaccagaaa tcgttccacc agtacctact ccagcaacaa aggcatctaa
    44401 tccatcttta ccgaaagcag ctagtatctc agctcctgtt gttctttcgt gtacttctgg
    44461 attagctgga ttgtcaaatt gaagaggaag gaaaccatca cgttcagcag cgatttcttg
    44521 agccttagca atagcacctt tcattccctc gctaccagga gttaggacga gttcagcacc
    44581 ataagcttgg ataattttac gtcgttctac actcatagtt tcaggcataa cgatgacgac
    44641 tttataccct ttagcagcac ctacccatga aagtccaata ccggtgtttc cacttgttgc
    44701 ttcaacaata gtagaaccaa gtttcagaat accatcttgt tcagcttttt caatcatgct
    44761 aagggcaata cggtctttta cagatgaacc aggattaaat gcttcaagct ttatatagac
    44821 gtctgcagca ccttctggca cgatgttgtt aagtttaaca atcggtgttt gaccgattaa
    44881 ttcagtaatg ttgttataaa tagacatatg aatacctctt tgtataagat atctttagta
    44941 taacgctatc cataccattt gtaaaatata gaaatcctat cgaagcgata ggatttctat
    45001 atatcataga tcaaagtcat taattttcaa gtgattgcgt tcagttaatt ctagtaaata
    45061 ggtgtgaagg aaaacgatat caggtttcgt ttgaattgct tcattttcta gtatattttg
    45121 gtacgcatct ttttattttg ctcgctaaag tagttgtgag aatgtcaacg aaacgctgta
    45181 ttattcattg tttacactaa gtttacagga acttcaacct ctcgtaaacc ttggtcagtt
    45241 aaagtgactt ttccattaaa aaactccaca agtgcagctt taatagtttc tttttcttct
    45301 ttatcaacat aaatcatcgt atcgacttga tctgtaaagt ttgtatccag ctccatgaga
    45361 tcatgttctt taaggaagtt actgtactct tggtactgag cataagacat ttgaatagca
    45421 atgccagcct gttcttttat ttcaataata ccaatttctt tgacagctaa ggcgacactg
    45481 ccggcgtaag cacgaattag tcctccagcg cctagtttaa taccaccaaa gtagcgtgtc
    45541 acgaccacac agacattggt gagattgtga ttttctagta ccccaagcat gggaacacca
    45601 gcagtaccac taggctcacc atcatcactt gtacgtttaa tttcactacg ttctccaata
    45661 ataaaggcag agcagttatg tgtcgctttg tagtgttctt ttttgatggc agtaatgaag
    45721 tcacgagcct cttcttcgct ataaacacgc ttggcatggc agataaagcg agattttttg
    45781 atttcttctt ggacttggcc gtcctcttta attgtcctaa attccatgat ttaattgtac
    45841 taaaaaatca tctaaagtgc tagtttttac gaataaagaa gtatgaaagt aaatttagat
    45901 tatctcggtc gtttatttac tgagaatgaa ttaacagaag aagaacgtca gttggcggag
    45961 aaacttccag caatgagaaa ggagaagggg aaacttttct gtcaacgttg taatagcact
    46021 attctagcag aatggtattt gcccatcggt gcttactatt gtcgagagtg cttgctgatg
    46081 aagcgagtca gaagtgatca aactttatac tattttccgc aggaggattt tccgaagcaa
    46141 gatgttctca aatggcgcgg ccaattaact ccttttcaag agaaggtgtc agagggactg
    46201 cttcaagcag tagacaagca aaagccaacc ttagttcatg cggtaacagg agctggaaag
    46261 acagaaatga tttatcaagt agtggctaaa gtgatcaatg cgggtggtgc agtgtgtttg
    46321 gctagtcctc gcatagatgt ttgtttggag ctgtacaagc gcctgcaaca ggatttttct
    46381 tgcgggatag ctttgctaca tggagaatcg gaaccttatt ttcgaacacc actagttgtt
    46441 gcaacaaccc atcagttatt gaagttttat caagcttttg atttgctgat agtggatgaa
    46501 gtagatgctt ttccttatgt tgataatccc acgctttacc atgctgtcaa gaatagtgta
    46561 aaggagaatg gattgagaat ctttttaaca gcgacttcga ccaatgagtt agataaaaag
    46621 gtccgtttag gagaactaaa aagactgaat ttaccgagac ggtttcatgg aaatccgttg
    46681 attattccaa aaccaatttg gttatcggat tttaatcgct acttagacaa gaatcgtttg
    46741 tcaccaaagt taaagtccta tattgagaag cagagaaaga cagcttatcc gttactcatt
    46801 tttgcttcag aaattaagaa aggggagcag ttagaagaaa tcttacagga gcaatttcca
    46861 aatgagaaaa ttggctttgt atcttctgta acagaggatc gattagagca agtacaagct
    46921 tttcgagatg gagaactgac aatacttatc agtacgacaa tcttggagcg tggagttacc
    46981 ttcccttgtg tggatgtttt cgtagtagag gccaatcatc gtttgtttac caagtctagt
    47041 ttgattcaga ttggtggacg agttggacga agcatggata gaccgacagg agatttgctt
    47101 ttcttccatg atgggttaaa tgcttcaatc aagaaggcga ttaaggaaat tcagatgatg
    47161 aataaggagg ctggtctatg aagtgcttgt tatgtgggca gactatgaag actgttttaa
    47221 cttttagtag tctcttactt ctgaggaatg atgactcttg tctttgttca gactgtgatt
    47281 ctacttttga aagaattggg gaagagaact gtccaaattg tatgaaaaca gagttgtcaa
    47341 caaagtgtca agattgtcaa ctttggtgta aagaaggagt tgaagtcagt catagagcga
    47401 tttttactta caatcaagct atgaaggatt ttttcagtcg gtataagttt gatggagact
    47461 tcctgttaag aaaagttttc gcttcatttt taagtgagga gttgaaaaag tacaaagagt
    47521 atcaatttgt tgtaattccc ctaagtcctg atagatatgc taatagagga tttaatcagg
    47581 ttgagggctt ggtagaggca gcaggctttg agtatctgga tttattagag aaaagagaag
    47641 agagagccag ttcttctaaa aatcgttcag agcgcttggg gacagaactt cctttcttta
    47701 ttaaaagtgg agtcactatt cctaaaaaaa tcctacttat agatgatatc tatactatag
    47761 gagcaactat aaatcgtgtt aagaaactgt tggaagaagc tggtgctaag gatgtaaaaa
    47821 cattttccct tgtaagatga ggaaaaaatt tgcaaaaata gaatgaaagc gttataataa
    47881 aatcataaaa acaaaaatgt ttagaaagaa ggtactcata tgattaaata tagtatccgt
    47941 ggtgaaaacc tagaagtaac agaagcaatt cgtgattatg tagtttctaa actcgaaaag
    48001 atcgaaaagt acttccaacc agaacaagag ttggatgccc gaattaactt aaaagtttat
    48061 cgtgaaaaaa cggctaaagt ggaagtaacg attccgcttg gatctattac tctccgcgca
    48121 gaagatgtat ctcaagatat gtatggttca attgaccttg taactgataa aattgaacgt
    48181 cagattcgta aaaataaaac aaaaatcgag cgtaaaaata aaaataaggt agcaactggt
    48241 caattattta cagatgcttt ggtggaagat tcaaatattg tccagtctaa agttgttcgt
    48301 tcaaaacaaa ttgatttaaa accaatggat ttggaagaag caattctaca aatggattta
    48361 ttggggcatg atttctttat ctatgtggat gttgaagatc agacaaccaa tgtgatttat
    48421 cgtcgtgagg atggcgaaat tggtttgtta gaggttaaag aatcttaatt tcaatatgtg
    48481 taaaggtagg tttactgaat tgtaaactac ctttttctta taattgatag aattactgat
    48541 tacactttta aaaagtcgct ttttgagggg tattatggta taatgggtgc caagaggttt
    48601 tgaatgaaaa aattttatgt aagtccaatt tttcctattc tagtaggatt gattgcgttt
    48661 ggagtcttat ccactttcat tatttttgtt aataataatc tgttgacggt tttaattttg
    48721 tttctttttg taggaggcta tgttttttta tttaagaaac tgagagtgca ttatacaagg
    48781 agtgatgtag aacagataca gtatgtaaac caccaagcgg aagaaagttt gacagctcta
    48841 ttggaacaga tgcctgtagg tgttatgaaa ttgaatttat cttctggaga ggttgagtgg
    48901 tttaatccct atgctgaatt gattttgacc aaggaagatg gtgattttga tttagaagct
    48961 gttcaaacga ttatcaaggc ttcagtagga aatccgtcta cttatgccaa gcttggtgag
    49021 aagcgttatg ctgttcatat ggatgcttct tccggtgttt tgtattttgt agatgtatcc
    49081 agggaacaag ccataacaga tgaattggta acaagtagac cagtgattgg gattgtctct
    49141 gtggataatt atgatgattt ggaggatgca acttctgagt cagatattag tcaaatcaat
    49201 agttttgtag ctaattttat atcagagttt tcagaaaaat acatgatgtt ttctcgtcgg
    49261 gtaagtatgg atcgatttta tctatttact gactacacgg tgcttgaggg cttgatgaat
    49321 gataaatttt ctgttattga tgctttcaga gaagagtcga aacagagaca gttgcccttg
    49381 accttaagta tgggattttc ttatggcgat ggaaatcatg atgagatagg gaaagttgct
    49441 ttgctcaatt tgaacttggc tgaagtacgt ggtggcgacc aggtggttgt taaggaaaac
    49501 gacgaaacga aaaatccagt ttattttggt ggtgggtctg ctgcttcaat caagcgtaca
    49561 cggactcgta cgcgcgctat gatgacagct atttcagata agattcggag tgtagatcag
    49621 gtttttgtag tcggtcacaa aaatttagac atggatgctt tgggctctgc tgtaggtatg
    49681 cagttgttcg ccagcaatgt gattgaaaat agctatgctc tttatgatga agaacaaatg
    49741 tctccagata ttgaacgagc tgtttcattc atagaaaaag aaggagttac gaagttgttg
    49801 tctgttaagg atgcaatggg gatggtgacc aatcgttctt tgttgattct tgtagaccat
    49861 tcaaagacag ccttaacatt atcaaaagaa ttttatgatt tatttaccca aaccattgtt
    49921 attgaccacc atagaaggga tcaggatttt ccagataatg cggttattac ttatatcgaa
    49981 agtggtgcaa gtagtgccag tgagttggta acggaattga ttcagttcca gaattctaag
    50041 aaaaatcgtt tgagtcgtat gcaagcaagt gttttgatgg ctggtatgat gttggatact
    50101 aaaaatttca cctcgcgagt aactagtcgg acatttgatg ttgctagcta tctcagaacg
    50161 cgcggaagtg atagtattgc tatccaggaa atcgctgcga cagattttga agaatatcgt
    50221 gaggtcaatg aacttatttt acaggggtgt aaattaggtt cagatgtact aatagcagag
    50281 gctaaggaca cgaaatgcta tgatacagtt gttattagta aggcagcaga tgccatgtta
    50341 gccatgtcag gtattgaagc gagttttgtt cttgcgaaga atacacaagg atttatctct
    50401 atctcagctc gaagtcgtag taaactgaat gtacaacgga ttatggaaga gttaggcggt
    50461 ggaggccact ttaatttggc agcagctcaa attaaagatg taaccttgtc agaagcaggt
    50521 gaaaaactga cagaaattgt attaaatgaa ataaaggaaa aggagaaaga agaatgaaag
    50581 taatcttttt agcagatgtt aaaggaaaag gtaaaaaagg cgaaattaag gaagtaccaa
    50641 cagggtatgc gcaaaacttt cttatcaaaa agaatctagc caaagaagcg actgctcaag
    50701 ctgtaggtga acttcgtggt aaacaaaaat cggaagaaaa agctcacgct gagatgattg
    50761 cagaaggaaa agcaattaaa gcacaacttg aagcagaaga aactgttgta gaatttgttg
    50821 aaaaagttgg tccagatggt cgtacctttg gttctattac caataagaag attgcagaag
    50881 aattgcaaaa gcaatttgga attaagattg ataaacgtca tattcaagta caagctccga
    50941 ttcgagcggt tggtttgatt gatgtgccag tgaaaatcta tcaagatatc acaagtgtaa
    51001 tcaatcttcg tgtgaaagaa ggataagttt acaccttctt gacaagattg taaaaggaag
    51061 ggaagtctga tggcagaagt agaagagtta cgagtacaac ctcaagatat cttagctgag
    51121 caatccgttt taggggctat ctttattgat gagagtaaac ttgtttttgt gcgagaatac
    51181 attgagtctc gggacttttt taagtatgcc catcgtttga ttttccaagc catggtcgat
    51241 ttatccgatc gtggtgatgc catagatgca acaacggttc gtactatcct tgataatcaa
    51301 ggtgatttac agaatattgg tggcttgtct tacttggttg agattgtcaa ttctgtgcca
    51361 acttctgcta atgcggagta ttatgctaag attgttgcag aaaaagcaat gctacgtcgt
    51421 ttaattgcca agttgacaga gtctgtcaac caagcttacg aagcgtcaca accagctgat
    51481 gaaattattg ctcaggcaga aaaagggctg attgatgtca gtgaaaatgc aaatcgaagc
    51541 gggtttaaga acattcgaga tgtgttgaat ctcaactttg gaaatctgga agctcgctcg
    51601 caacaaacga ccgatattac aggtattgcg acaggttatc gtgatttgga tcatatgaca
    51661 acaggacttc atgaggagga gttgattatc ttagcagctc gtccagcagt tggtaagaca
    51721 gcatttgcct tgaatatcgc tcagaatatt gggactaagt tggacaaaac ggttgctatt
    51781 ttttcactcg aaatgggtgc ggaaagcttg gtagaccgta tgttagctgc agaaggcttg
    51841 gtggagtcac attctatccg tacagggcaa ttgacagatg aggagtggca aaaatatact
    51901 attgctcagg gtaatctagc taacgccagt atctatatcg atgatacgcc aggtattcgg
    51961 attacagaga ttcgttctcg ttctcgtaaa ttggctcaag aaactggaaa tcttggtttg
    52021 attttgatag actatttgca acttatcacg ggaactggtc gagaaaatcg tcaacaagaa
    52081 gtttctgaaa tttctcgtca gttgaaaata ctagccaagg aattgaaggt tccagtaatc
    52141 gctctgagtc agctttctcg tggtgtagaa caacgtcagg acaagagacc ggtcttgtct
    52201 gatattcgtg aatctgggtc tattgagcag gacgctgata tcgtagcttt tctctatcgc
    52261 gatgactact atgaacgtgg tggtgaagaa gaggagggta tcccaaataa taaggtggaa
    52321 gttattatcg agaaaaaccg tagtggagct cgtggaacag tggaattgat tttccaaaaa
    52381 gaatacaata aattttcaag tatctcaaag agggaggcat aagatgtcag atgcatttac
    52441 agatgtagcc aagatgaaaa aaatcaaaga agaaatcaag gcacatgagg gacaagtcgt
    52501 agaaatgact ttggagaatg gtcgtaagcg ccaaaaaaat agattgggta agctaattga
    52561 agtttatcca tccctattta ttgtggagtt tggggatgtg gaaggagata aacaagttaa
    52621 tgtttacgtt gaatccttta cttactcaga tattcttaca gaaaagaatt tgattcatta
    52681 tcttgactaa agtgagaaat tttctcactt tttctttttt ctccgaataa tttaggtgaa
    52741 ggcaatcatc gctttatatt attttttaag gaggaagaat gaaaatttta ccgtttatag
    52801 caagaggaac aagttattac ttgaagatgt cagttaaaaa gcttgttcct tttttagtag
    52861 taggattgat gctagcagct ggtgatagtg tctatgccta ttccagagga aatggatcga
    52921 ttgcgcgtgg ggatgattat cctgcttatt ataaaaatgg gagccaggag attgatcagt
    52981 ggcgcatgta ttctcgtcag tgtacttctt ttgtagcctt tcgtttgagt aatgtcaatg
    53041 gttttgaaat tccggcagct tatggaaatg cgaatgaatg gggacatcgt gctcgtcggg
    53101 aaggttatcg tgtagataat acaccgacga ttggttccat tacttggtct actgcaggaa
    53161 cttatggtca tgttgcctgg gtgtcaaatg taatgggaga tcagattgag attgaggaat
    53221 ataactatgg ttatacagaa tcctataata aacgaattat aaaagcaaac acgatgacag
    53281 gatttattca ttttaaagat ttggatggtg gcagtgttgg gaatagtcaa tcctcaactt
    53341 caacaggcgg aactcattat tttaagacca agtctgctat taaaactgaa cccctagtta
    53401 gtgcaactgt gattgattac tattatcctg gagagaaggt tcattatgat caaattctcg
    53461 aaaaagacgg ctacaagtgg ttgagttata ctgcctataa tggaagctat cgttatgttc
    53521 aattggaggc tgtgaataaa aatcctctag gtaattctgt tctttcttca acaggtggaa
    53581 ctcattattt taagaccaag tctgctatca aaactgaacc cctagttagt gcaactgtga
    53641 ttgattacta ttatcctggg gagaaggttc attatgatca gatacttgaa aaagacggct
    53701 acaagtggtt gagttatacg gcttataacg gaagtcgtcg ctatatacag ctagagggag
    53761 tgacttcttc acaaaattat cagaatcaat caggaaatat ctctagctat ggatccaata
    53821 atagttcaac tgtcggttgg aagaaaataa atggtagttg gtatcatttc aaatcaaatg
    53881 gttctaaatc aacaggatgg ctgaaagatg gttctagctg gtattatttg aaattatctg
    53941 gtgaaatgca gacaggatgg ttaaaggaga atggctcgtg gtattatctg ggtagttcag
    54001 gggcaatgaa aacaggctgg taccaggtct ctggtaagtg gtattattct tactcttcag
    54061 gcgccttagc tgttaatacg acggtggatg gctacagagt aaacagtgat ggagaacgag
    54121 tatagaaaat tggagtagga gaaatttcct gctcttttct gtaagcagtt tccttgacat
    54181 ttttcttatt ttgcgctatc atatatacat ataatatatg ggagtctgtg tacagtctga
    54241 gaggaagtgt taaacttcga ccgcacctga tctgggtaat gccagcggag ggaacgatac
    54301 ttagtctaat tttgcacctt ttccatgtat ggtaaaggtt tttctttttt taaaaaggaa
    54361 aacgagaaga ggaggttctt atgaaagcaa gcattgcctt gcaagtttta cccctagcac
    54421 aggggattga tcggatagct gttattgatc aggtcattgc ttatctgcaa actcaagaag
    54481 tgacgatggt agtgacacca tttgaaacgg tcttggaagg ggagtttgat gagcttatgc
    54541 gcattctaaa agaagcgctg gaagtggcag ggcaggaggc agacaatgtc tttgccaatg
    54601 tcaaaataaa tgtaggagag attttaagta ttgatgagaa acttgagaag tatactgaga
    54661 cgccacatta gtctattggg ctttctcgga gtcttgtcaa tctggcagtt agcaggtttt
    54721 cttaaacttc tccccaagtt tatcctgccg acacctcttg aaattctcca gccctttgtt
    54781 cgtgacagag aatttctctg gcaccatagc tgggcgacct tgagagtggc tttactgggg
    54841 ctgattttgg gagttttgat tgcctgtctt atggctgtgc tcatggatag tttgacttgg
    54901 ctcaatgacc tgatttaccc tatgatggtg gttattcaga ccattccgac cattgccata
    54961 gctcctatcc tggtcttgtg gctaggttat gggattttgc ccaagattgt cttgattatc
    55021 ttaacgacaa cttttcccat catcgtcagc attttggacg gttttaggca ttgcgacaag
    55081 gatatgctga ccttgtttag tctgatgcgg gccaagcctt ggcaaatcct gtggcatttt
    55141 aaaattccag tcagcctgcc ctacttttat gctggtctga gggtcagtgt ctcctacgct
    55201 tttatcacaa cagtggtatc tgagtggttg ggaggttttg aaggtcttgg tgtttatatg
    55261 attcagtcta aaaaactgtt tcagtatgat accatgtttg ccattattat tctggtgtcg
    55321 attatcagtc ttttgggtat gaagctggtc gatatcagtg aaaaatatgt gattaaatgg
    55381 aaacgtactt aaaatagagc gtttttgaaa aagaaaagag gaaatcaaaa tgaagaaaac
    55441 atggaaagtg tttttaacgc ttgtaacagc tcttgtagct gttgtgcttg tggcctgtgg
    55501 tcaaggaact gcttctaaag acaacaaaga ggcagaactt aagaaggttg actttatcct
    55561 agactggaca ccaaatacca accacacagg gctttatgtt gccaaggaaa aaggttattt
    55621 caaagaagct ggagtggatg ttgatttgaa attgccacca gaagaaagtt cttctgactt
    55681 ggttatcaac ggaaaggcac catttgcagt gtatttccaa gactacatgg ctaagaaatt
    55741 ggaaaaagga gcaggaatca ctgccgttgc agctattgtt gaacacaata catcaggaat
    55801 catctctcgt aaatctgata atgtaagcag tccaaaagac ttggttggta agaaatatgg
    55861 gacatggaat gacccaactg aacttgctat gttgaaaacc ttggtagaat ctcaaggtgg
    55921 agactttgag aaggttgaaa aagtaccaaa taacgactca aactcaatca caccgattgc
    55981 caatggcgtc tttgatactg cttggattta ctacggttgg gatggtatcc ttgctaaatc
    56041 tcaaggtgta gatgctaact tcatgtactt gaaagactat gtcaaggagt ttgactacta
    56101 ttcaccagtt atcatcgcaa acaacgacta tctgaaagat aacaaagaag aagctcgcaa
    56161 agtcatccaa gccatcaaaa aaggctacca atatgccatg gaacatccag aagaagctgc
    56221 agatattctc atcaagaatg cacctgaact caaggaaaaa cgtgactttg tcatcgaatc
    56281 tcaaaaatac ttgtcaaaag aatacgcaag cgacaaggaa aaatggggtc aatttgacgc
    56341 agctcgctgg aatgctttct ataaatggga taaagaaaat ggtatcctta aagaagactt
    56401 gacagacaaa ggcttcacca acgaatttgt gaaataatga cagaaattag actagagcac
    56461 gtcagttatg cctatggtca ggagaggatt ttagaggata tcaacctaca ggtgacttca
    56521 ggcgaagtgg tttccatcct aggcccaagt ggtgttggaa agaccaccct ctttaatcta
    56581 atcgctggga ttttagaagt tcagtcaggg agaattgtcc ttgatggtga agaaaatccc
    56641 aaggggcgcg tgagttatat gttgcaaaag gatctgctct tggagcacaa gacggtgctt
    56701 ggaaatatca ttctgcccct cttgattcaa aaggtggata aggcagaagc tatttcccga
    56761 gcggataaaa ttcttgcgac cttccagctg acagctgtaa gagacaagta tcctcatgaa
    56821 cttagcggtg ggatgcgcca gcgtgtagcc ttactccgga cctacctttt tgggcacaag
    56881 ctctttctct tagatgaggc ctttagcgcc ttggatgaga tgacaaagat ggaactccac
    56941 gcttggtatc ttgagattca caaacagttg cagctaacaa ctctgatcat cacgcatagt
    57001 attgaggagg ccctcaatct cagcgaccgc atctatatct tgaaaaatcg ccctgggcag
    57061 attgtttcag aaattaaact agattggtct gaagatgagg acaaggaagt ccaaaagatt
    57121 gcctacaaac gtcaaatctt ggcagaatta ggcttagata agtagaaaaa tagggagttg
    57181 gtgaagatta tcctttacca gcgccctttt tcttttaaaa atgagaaaat ttcggtataa
    57241 tagtcaaaca aggtcaaggt ttaaagagag aggtgggttt gttatgagat ttaaaaatac
    57301 atcggatcat attgaggcct acatcaaggc gattttagat caatctggta tcgtggagtt
    57361 gcaacggagt cagttggcag atacctttca ggttgttcct agtcagatta actacgtgat
    57421 caagacacgc tttacggaaa gtagaggcta cttggttgaa agtaagcgtg gtggcggagg
    57481 ctacattcgt ataggacgga ttgagttttc tagtcatcat gaaatgctcc gggatctgct
    57541 ttactcgatt ggtgagcgag tcagtcaaga aatttatgag gatattctcc agcttttggt
    57601 tgagcaggaa ttgatgacca agcaggagat gaatttgcta gaatcagtag ctttggatcg
    57661 cgttttagga gaagaagctc cagttgttcg agcaaacatg ctacgtcagg tcatacaaga
    57721 ggtagataga aaagggaagt aagatgaact attcaaaagc attgaatgaa tgtatcgaaa
    57781 gtgcctacat ggttgctgga cattttggag ctcgttatct agagtcgtgg cacttgttga
    57841 ttgccatgtc taatcacagt tatagtgtag caggggcaac tttaaatgat tatccgtatg
    57901 agatggaccg tttagaagag gtggctttgg aactgactga aacggactat agccaggatg
    57961 aaacctttac ggaattgccg ttctcccgtc gtttgcaggt tctttttgat gaagcagagt
    58021 atgtagcgtc agtggtccat gctaaggtac tagggacaga gcacgtcctc tatgcgattt
    58081 tgcatgatgg caatgccttg gcgactcgta tcttggagag ggctggtttt tcttatgaag
    58141 acaagaaaga tcaggtcaag attgctgccc ttcgtcgaaa tttagaagaa cgtgcaggct
    58201 ggactcgtga agatctcaag gctttacgcc aacgccatcg tacagtagct gacaagcaaa
    58261 attctatggc caatatgatg ggcatgccgc agactcctag tggtggtctc gaggactata
    58321 cgcatgattt gacagagcaa gcgcgttctg gcaagttaga accagtcatc ggtcgggaca
    58381 aggaaatctc gcgtatgatt caaatattga gccgtaagac taagaacaac cctgtcttgg
    58441 ttggggatgc tggtgtcggg aaaacagctc tggcccttgg tcttgcccag cgtattgcta
    58501 gtggtgacgt gcctgcggaa atggctaaga tgcgcgtgtt agaacttgat ttgatgaatg
    58561 tcgttgcagg gacacgcttc cgtggtgact ttgaagaacg catgaataat atcatcaagg
    58621 atattgaaga agatggccaa gtcatcctct ttatcgatga actccacacc atcatgggtt
    58681 ctggtagcgg gattgattcg actctggatg cggccaatat cttgaaacca gccttggcgc
    58741 gtggaacttt gagaacggtt ggtgccacca ctcaggaaga atatcaaaaa catatcgaaa
    58801 aagatgcggc tctttctcgt cgtttcgcta aagtgacgat tgaagaacca agtgtggcag
    58861 atagtatgac tattttacaa ggtttgaagg cgacttatga gaaacatcac cgtgtacaaa
    58921 tcacagatga agcggttgaa acagcggtta agatggctca tcgttattta accagtcgtc
    58981 acttgccaga ctctgctatc gacctcttgg acgaagcagc agcaacagtg caaaataagg
    59041 caaagtatgt aaaagcagac gattcagatt tgagtccagc tgacaaggcc ctgatggatg
    59101 gcaagtggaa acaggcagcc cagctaatcg caaaagaaga ggaagtacct gtctacaaag
    59161 acttggtgac agagtctgat attttgacca ccttgagtcg cttgtcagga atcccagttc
    59221 aaaaactgac tcagactgac gctaagaaat atctaaatct tgaagcagaa ctccataaac
    59281 gggttatcgg tcaagatcaa gctgtttcaa gtattagtcg tgcgattcgc cgtaatcagt
    59341 caggaattcg cagtcacaag cgtccgatcg gttcctttat gttcctagga cccacaggtg
    59401 tcggtaagac cgagttggcc aaggctttgg cagaagttct ctttgatgac gaatcagccc
    59461 ttatccgctt tgatatgagt gagtatatgg agaaattcgc agccagccgt ctaaatggag
    59521 ctcctccagg ctatgtgggt tacgaagaag gtggggagtt gacagagaag gttcgcaata
    59581 aaccctattc cgttctcctc tttgatgagg tagagaaggc tcacccagat atctttaatg
    59641 ttctcttgca ggttctggat gacggtgtct tgacagatag caagggacgc aaggtcgatt
    59701 tttcaaatac cattatcatt atgacatcga acctaggtgc gactgccctt cgtgatgata
    59761 agactgttgg ttttggggct aaggatattc gttttgacca ggaaaatatg gaaaaacgca
    59821 tgtttgaaga actgaaaaaa gcttatagac cggaattcat caaccgtatt gatgagaagg
    59881 tggtcttcca tagcctatct agtgaccata tgcaggaagt ggtgaagatt atggtcaagc
    59941 ctttagtggc aagtttggct gaaaaaggca ttgacttgaa attacaagct tcagctctga
    60001 aattgttagc aaatcaagga tatgacccag agatgggagc tcgcccactt cgcagaaccc
    60061 tgcaaacaga agtggaggac aagttggcag aacttcttct caagggagat ttagtggcag
    60121 gcagcacact taagattggt gtcaaagcag gccagttaaa atttgatatt gcataaaaga
    60181 ataaaagtat cagcatctga ccataagtca cagtggagtg aaactcaatg aaaatcaaag
    60241 aacaaactag gcagctagcc gcaggttgct caaaacactg ttttgaggtt gtagatagag
    60301 ctgacgtggt ttggagagat tttcgaagag tataagctgc aagatgaatg attttcttgt
    60361 attgacgttg ttgttgacaa aaagtagcgg ataaatgaaa tccattccat tatcatagat
    60421 gataggctgg taggaaattt tcaaatagca tacaggaaat agatgtatgg agttctggta
    60481 gtagaaaggg agagagatga acattttagt tgcagatgac gaggaaatga ttagagaagg
    60541 aattgcagca tttctgacag aagagggtta tcatgtcatt atggctaagg atggacaaga
    60601 ggtcttggaa aaatttcaag atctccctat ccatctcatg gtattggatt taatgatgcc
    60661 taggaagagt ggttttgaag tgttaaaaga aatcaatcaa aagcacgata ttcctgtcat
    60721 cgtcttgagt gctctgggag atgaaactac tcagtcacag gtatttgatc tctatgctga
    60781 tgatcatgtg acaaaacctt tttctttggt actgcttgtc aagcgtatta aggcgcttat
    60841 cagacgttac tacgtcatag aggatatttg gcgatatcag gatgtaacag tggattttac
    60901 ctcttacaaa gcacattata aaaatgaaga aattgatctc aaaccaaagg aattactggt
    60961 actaaagtgt ttgattcagc ataaaaatca agttttaagt agagagcaga tattggaaga
    61021 aatttcaaaa gatgtagctg atttaccttg tgatagggtc gttgatgtct atattcgtac
    61081 tcttcgcaaa aaattagctt tagattgtat cgtgactgtg aaaaatgttg ggtataagat
    61141 tagcttatga taaaaaatcc taaattatta accaagtctt ttttaagaag ttttgcaatt
    61201 ctaggtggtg ttggtctagt cattcatata gctatttatt tgacctttcc tttttattat
    61261 attcaactgg agggggaaaa gtttaatgag agcgcaagag tgtttacgga gtatttaaag
    61321 actaagacat ctgatgaaat tccaagctta ctccagtctt attcaaagtc cttgaccata
    61381 tctgctcacc ttaaaagaga tattgtagat aagcggctcc ctcttgtgca tgacttggat
    61441 attaaagatg gaaagctatc aaattatatc gtgatgttag atatgtctgt tagtacagca
    61501 gatggtaaac aggtaacagt gcaatttgtt cacggggtgg atgtctacaa agaagcaaag
    61561 aatattttgc ttttgtatct cccatataca tttttggtta caattgcttt ttcctttgtt
    61621 ttttcttatt tttatactaa acgcttgctc aatcctcttt tttacatttc agaagtgact
    61681 agtaaaatgc aagatttgga tgacaatatt cgttttgatg aaagtaggaa agatgaagtt
    61741 ggtgaagttg gaaaacagat taatggtatg tatgagcact tgttgaaggt tattcatgag
    61801 ttggaaagtc gtaatgagca aattgtaaaa ttgcaaaatc aaaaggtttc ctttgtccgc
    61861 ggagcatcac atgagttgaa aaccccttta gccagtctta gaattatcct agagaatatg
    61921 cagcataata ttggagatta caaagatcat ccaaaatata ttgcaaagag tataaataag
    61981 attgaccaga tgagccactt attggaagaa gtactggagt cttctaaatt ccaagagtgg
    62041 acagagtgtc gtgagacctt gactgttaag ccagttttag tagatatttt atcacgttat
    62101 caagaattag ctcattcaat aggtgttaca attgaaaatc aattgacaga tgctaccagg
    62161 gtcgtcatga gtcttagggc attggataag gttttgacaa acctgattag taatgcaatt
    62221 aaatattcag ataaaaatgg gcgcgtaatc atatccgagc aagatggcta tctctctatc
    62281 aagaatacat gtgcgcctct aagtgaccaa gaactagaac atttatttga tatattctat
    62341 cattctcaaa tcgtgacaga taaggatgaa agttccggtt tgggtcttta cattgtgaat
    62401 aatattttag aaagctatca aatggattat agttttctcc cttatgaaca cggtatggaa
    62461 tttaagatta gcttgtagac agattagttt tttattaaag ttcatatagg gttaacataa
    62521 gtgtgttatt ctttgtgtag ataaaagaaa ggatactaat atggtattag cgattatttt
    62581 agtaacattc tttattcgat tgattttttt aaagcgttcg atagagaatg agaaacgaat
    62641 ccttagcaat ggcgggaaag aatttggagt tgagaataca aaacgattaa ctatggctca
    62701 tattgttttt tatctctctt gcttggttga ggcaatggtg cacaagacaa tttttgatgg
    62761 catgggcatg gttggtttag tcttgcttat tttttctatg ctgatgttga tgttggtgat
    62821 tcacttgttg ggagatattt ggacagtgaa gcttatgctt gtcaataatc acaaatatgt
    62881 agatcatatc ttgtttagga cagtaaaaca tcctaattac tttttaaata ttcttcctga
    62941 gttgattggc ttgaccttgt tgagtcatgc ttatgtgact tttgttttag tttttccagt
    63001 ttatgcagtt attttgtatc gacgaatagc tgaagaggaa aagctattac atgaagttat
    63061 aatcccaaat ggaagcataa agagataaat acaaaattcg atttatatac agttcatatt
    63121 gaagtgatat agtaaggtta aagaaaaaat atagaaggaa ataattatgt ttgcatcaaa
    63181 aagcgaaaga aaagtacatt attcaattcg taaatttagt gttggagtag ctagtgtagt
    63241 agttgctagc ttgttcttag gaggagtagt ccatgcagaa ggggttagaa gtggggatac
    63301 ccccaaggtt acatctagtg ggcaagatat atcgaagaag tatgctgatg aagtcaagtc
    63361 gcatctagaa aaaatattga gtgagatcca attagataaa agaaaacata cccaaaatct
    63421 cgccttcaac aaaaagttga gcagaattca aacggagtat ttctatttaa aaaagaagtt
    63481 gaaagctgag ttgacgtcaa aaacaaaaga agagttaacg tcaaaaacag aagagttgac
    63541 gtcaaaaaca aaaaaagagt tagacgcagc ttttgagcag tttaaaaaag atacattatc
    63601 aacagaacca gaaaaaaagg ttgcagaagc tgagaagaag gtagcagaag ctaagaaaaa
    63661 agccgaggat caaaaagaag aagatcgtcg taactaccca accaatactt acaaaacgct
    63721 tgaacttgaa attgctgagt tcgatgtgaa agttaaagaa gcggagcttg aactattaaa
    63781 agagaaagct aaggaatctc gagacgagga aaaaattaag caagcagaag cggaagttga
    63841 gagtaaacaa gctgaggcta caaggttaga aaacatcaag acagatcgta aaaaagcaga
    63901 agaagaagct aaacgaaaag cagatgctaa gttgaaggaa gctaatgtag cgacttcaga
    63961 tcaaggtaaa ccaaaggggc gggcaaaacg aggagttcct ggagagctag caacacctga
    64021 taaaaaagaa aatgatgcga agtcttcaga ttctagcgta ggtgaagaaa ctcttccaag
    64081 ctcatccctg aaatcaggaa aaaaggtagc agaagctgag aagaaggttg aagaagctga
    64141 gaaaaaagcc aaggatcaaa aagaagaaga tcgccgtaac tacccaacca atacttacaa
    64201 aacgcttgaa cttgaaattg ctgagtccga tgtgaaagtt aaagaagcgg agcttgaact
    64261 agtaaaagag gaagctaagg aacctcgaga cgaggaaaaa attaagcaag caaaagcgga
    64321 agttgagagt aaacaagctg aggctacaag gttagaaaaa atcaagacag atcgtaaaaa
    64381 agcagaagaa gaagctaaac gaaaagcagc agaagaagat aaagttaaag aaaaaccagc
    64441 tgaacaacca caaccagcgc cggctcctca accagaaaaa ccagctccaa aaccagaaaa
    64501 accagctcca gctccaaaac cagagaatcc agctgaacaa ccagcacaac catctactcc
    64561 aaaaacaggc tggaaacaag aaaacggtat gtggtacttc tacaatactg atggttcaat
    64621 ggcgacagga tggctccaaa acaatggctc atggtactac ctcaacagca atggcgctat
    64681 ggcgacagga tggctccaaa acaatggttc atggtactat ctaaacgcta atggttcaat
    64741 ggcaacagga tggctccaaa acaatggttc atggtactac ctcaacgcta atggttcaat
    64801 ggcgacagga tggctccaaa acaatggttc atggtactac ctaaacgcta atggtgatat
    64861 ggcgacagga tggctccaaa acaatggctc atggtactac ctaaacgcta atggtgatat
    64921 ggcgacagga tggctccaaa acaacggttc atggtactac ctaaacagca atggtgctat
    64981 ggtaacagga tggctccaaa acaatggctc atggtattac ctcaacgcta atggtgatat
    65041 ggcgacaggt tgggtgaaag atggagacac ctggtactat cttgaagcat caggtgctat
    65101 gaaagcaagc caatggttca aagtatcaga taaatggtac tatgtcaatg gctcaggtgc
    65161 ccttgcagtc aacacaactg tagatggcta tggagtcaat gccaatggtg aatgggtaaa
    65221 ctaaacctaa tataactagt taatactgac ttcctgtaag aactttttaa agtattccct
    65281 acaaatacca tatcctttca gtagataata tacccttgta ggaagtttag attaaaaaat
    65341 aactctgtaa tctctagccg gatttatagc gctagagact acggagtttt tttgatgagg
    65401 aaagaatggc ggcattcaag agactcttta agagagttac gggttttaaa ctattaagcc
    65461 ttctccaatt gcaagagggc ttcaatctct gctagggtgc tagcttgcga aatggctcca
    65521 cggagtttgg cagcgccaga tgttccacgg agatagtgag gagcgaggcc gcggaattca
    65581 cgaactgcga cgttttctcc tttgaggtta atcaatcgtt tcaagtgttc gtaggcgatc
    65641 ttcatcttgt cttcaaaggt caaatcaggt aggatttctc ctgtttcaaa gtaatggttg
    65701 atttggttga agaggtaagg atttcccatg gcagctcggc caatcatgac tgcgtcagca
    65761 ccaacttctt cgatgcgttg cttggcttct tggacagtac ggatatcacc gttggcgatg
    65821 aatggaatct tggttagagc ttgggcaacc ttgtaaaggg tctcaaggtc tgcgtggcca
    65881 gtatacattt gttcacgggt acggccatgc atggcgaggg cagaaacacc tgcagcttca
    65941 gcagcgaggg cattttctac tgccagagat gggtccgccc agccggtacg cattttgaca
    66001 gtaagtggga tatcaaggac agactggacc ttgttgatga tggagtaaat cttgtctgga
    66061 tccttgagcc acatagcacc agcttcgttc ttcacgattt tgttgacagg gcagcccatg
    66121 ttgatatcga cgatatcggt cttggtgttt tcttggatga attctgctgc gcgtgctagg
    66181 ctgtcttcat cgctaccaaa aagttggata gagacagggt tttcgccctc atcgatatga
    66241 agcatgtgca gggttttttc gttgttgtat tggattccct tgtcagagac catttccatt
    66301 acaacgagtc cagctccgag ctcttttgcg atggtacgaa aggctgagtt ggtcacgcca
    66361 gccataggcg ctaaaacggt acgattggga atctcaacat tgccaatcat aaaaggtgta
    66421 ttaagatttg tcacgaatga gttcctccag gtccttttca tcaaagttgt aagtagtttg
    66481 gcagaattga caagtgattt ctgccccgtg gtcttcttct ttcatttcct gtaagtctga
    66541 gcttggaagg ctggcaagag cgttcataaa gcgttcatgg ctacagtcac attggaaacg
    66601 gatttcttct tcagaaagac gcttgtaggc ttcgtccccg tagatagcct tgaggagggc
    66661 ttcgatatgg tcgtcgcttt cgagaagagt agagatagct ggcatttctt ggatgcgttt
    66721 ttcaaagcga gcaatctctt ctttcttggc tcctggcaag acttgaacta ggaaaccacc
    66781 tgcaaccttg accttgtctt cctcgtccaa aaggacattg aggccgaccg ctgaaggcgt
    66841 ttgttggctt tcagtaaggt aaaaggcaag gtcttcaccg atttctccag agatgagggg
    66901 agttatagag ttgtaaggat ttccagtacc gtagtctgtg ataacgagga attgaccatt
    66961 tccaacaaaa ggtccgacta ggacttcacc agtcgcagtc tttttgatgt caacaccagg
    67021 attttgaacg tagcctttga cgttcccctt ggtatcagcg acggtgataa tagcacctag
    67081 agagctagat cccaacacct taactgtaag tttggtattt cctttttcat tggctgcgag
    67141 aatctggctg gcgataagag ttcgaccaag cgctacagtt gagctagctt gggtttgatg
    67201 tttttcttga gcagtgcgga cggtttcagt gctatcaagg acaaaagcac gaaaggctcc
    67261 gctttctgat atagttttaa taattttatc catagctact attttagcat aaaaatgccc
    67321 aaagggggag ccgtgtgttt actgattttc aggataatgg accaggaaat cagcatgaaa
    67381 ataaaaagag aaacagatta ttttagcatt tgtaagattt atgctatgct taaggtagaa
    67441 aatgaaaggg gtaacaaatg tatttaggag atttgatgga gaaagccgag tgtggtcaat
    67501 tttcaatcct ttcctttcta ttacaagagt ctcagacgac cgtcaaggct gtaatggaag
    67561 aaacaggatt ttcaaaagca accctaacca aatatgtcac cctgctcaat gacaaggctt
    67621 tggatagtgg cttagagctg gctattcact cagaagatga aaatctgcgt ctgtctatcg
    67681 gtgcagctac caaggggaga gatattcgga gcttgttttt ggagagtgct gttaaatacc
    67741 agattttggt ttatcttctc taccaccaac agtttttagc ccatcagctg gctcaagaat
    67801 tggtgattag cgaggctacg cttggtcgtc acttggctgg tttaaatcag attttgtcag
    67861 aatttgattt atccatccaa aatggacgtt ggcgaggtcc agagcatcag attcgctatt
    67921 tctatttctg tcttttccga aaggtctggt cgagtcagga atgggaaggt cacatgcaga
    67981 aaccagagag aaaacaggag attgccaatt tagaggaaat ctgcggtgca agtttgtctg
    68041 tggggcagaa attggacttg gttctctggg ctcacatcag tcaacaacgt cttcgggtca
    68101 atgcttgtca gtttcaagtc atagaagaga aaatgcgagg gtattttgac aatatcttct
    68161 atcttcgttt gctgagaaag gttccgtcct tttttgctgg gcaacatatt ccactaggag
    68221 ttgaggatgg tgagatgatg atattcttct cttttctcct atctcatcgc attcttcctc
    68281 ttcatactat ggaatatatt cttggttttg gagggcagtt ggcagattta ctgacgcaat
    68341 tgattcaaga aatgaagaag gaggaactat tgggggatta tacagaggac catgtcacct
    68401 atgaactgag tcagctttgt gctcaagtct atctctataa gggctatatt ttacaggatc
    68461 gctacaagta ccagttagag aatcgtcatc catatttact gatggaacat gattttaaag
    68521 agacagcaga ggagattttt catgctctac ctgcttttca acaggggaca gatttagata
    68581 agaagattct ctgggaatgg ctccagttaa tcgaatatat ggctgaaaac ggtggccagc
    68641 atatgcggat tggtctggat ttgacatctg gttttcttgt cttttcaagg atggcagcca
    68701 ttttgaaacg gtatttggaa tacaatcgtt ttattaccat tgaagcttat gaccctagtc
    68761 ggcattatga tttgctggtt accaataacc cgattcataa gaaggaacag accccagtct
    68821 attatttaaa aaatgacttg gatatggaag atttggcagg gattcgtcag ttattattca
    68881 cttaaaaggc ttggttaatc caggtctttt ttgtgaaatt cacacaatct cctcacattt
    68941 ttttaaaaat taaaaaaagt tgataaacaa gaaagcgctt tattttgtat actagtaagt
    69001 gtaaagagga aacacctcaa gatctttatc aggaggacag tacatgtcac aagaaaaata
    69061 catcatggcc attgaccagg gaactacaag ttctcgtgcc atcattttca acaaaaaagg
    69121 ggaaaaggtt agctcgagtc aaaaagagtt tacccagatt ttccctcagg caggttgggt
    69181 tgagcacaat gccaatgaaa tttggaactc tgttcagtca gttattgcgg gtgctttcat
    69241 cgaaagtggt gtcaagccaa atcaaatcga ggcaatcggg attaccaacc aacgtgaaac
    69301 aacggttgtc tgggataaga aaacaggact tcctatctac aatgctatcg tttggcagtc
    69361 acgccagaca gcacctttgg ctgagcaact aaaaagccaa ggttatgtgg aaaaattcca
    69421 tgaaaagact ggtttgatta ttgatgctta cttctctgct accaaggttc gttggatttt
    69481 ggatcatgta gaaggcgctc aagagcgagc agaaaaaggg gaattgctct ttggtactat
    69541 cgatacttgg ttggtttgga aattgactga cggtgcggct cacgtgactg actactcaaa
    69601 tgcagctcgt accatgcttt ataacattaa agaactcaaa tgggatgatg agattttgga
    69661 aatccttaac attccgaagg ctatacttcc agaagttcgt tctaactccg aaatctacgg
    69721 caagacagct ccattccatt tctacggtgg agaggtgcca atctcaggta tggctgggga
    69781 ccaacaagca gccctctttg gacagttggc ttttgagcca ggtatggtta agaatactta
    69841 tggaacaggc tctttcatca tcatgaatac tggggaagag atgcagttgt ctgaaaacaa
    69901 cctcttgaca accattggtt acggaatcaa cggtaaggtt tattatgcct tggaaggttc
    69961 tatcttcatc gcaggaagtg ctattcagtg gcttcgtgac ggtcttcgca tggttgaaaa
    70021 ttcaccagaa tctgaaaaat acgctcgtga ttctcacaac aacgatgaag tttatgtcgt
    70081 tccagccttt acaggtctag gcgctccata ctggaaccaa aatgctcgtg gttccgtctt
    70141 tggtttgact cgtggaacaa gcaaagaaga ctttatcaag gcgactttgc aatctattgc
    70201 ttatcaagtg cgtgacatca tcgacaccat gcaagtggat actcagactg ccattcaagt
    70261 attgaaggtg gatggtggtg cagccatgaa caacttcctc atgcagttcc aggcggatat
    70321 tttaggcatt gatattgcac gtgctaaaaa cttggaaaca acagctctag gagcggcctt
    70381 cctagcaggt ttatcagtag ggtactggaa agacttggac gagttgaaac tcttgaacga
    70441 gacaggagaa ctctttgagc catctatgaa tgaatctcgc aaggaacaac tctacaaggg
    70501 ctggaagaag gctgtgaaag caactcaagt ctttgcggaa gtagacgact aatactggca
    70561 gaataaagcg atttatttag aaagtgtgta aatatggaat tttcaaagaa aacacgtgaa
    70621 ttgtcaatta aaaaaatgca ggaacgcacc ctggacctct tgattatcgg tggaggaatc
    70681 acaggagctg gtgtagcctt gcaggcggca gctagcggtc ttgagactgg tttgattgaa
    70741 atgcaagact ttgcagaagg aacatctagt cgttcaacaa aattggttca cggaggtctt
    70801 cgctacctca aacaattcga cgtagaagtg gtctcagata cggtttctga acgtgcagtg
    70861 gttcaacaaa tcgctccaca cattccaaaa ccagatccaa tgctcttacc agtttacgat
    70921 gaagatggag caacctttag cctcttccgt cttaaagtag ccatggactt gtacgacctc
    70981 ttggcaggtg ttagcaacac accaactgcg aacaaggttt tgagcaagaa agaagtcttg
    71041 gaacgccagc caaacttgaa gaaggaaggc ttggtaggag gtggagtgta tcttgacttc
    71101 cgtaacaacg atgcgcgtct cgtgattgaa aacatcaaac gtgccaacca agacggtgcc
    71161 ctcattgcca accacgtgaa ggcagaaggc ttcctctttg acgaaagtgg caagattaca
    71221 ggtgttgtag ctcgtgatct cttgacagac caagtatttg aaatcaaggc ccgtctggtt
    71281 attaatacaa caggtccttg gagtgataaa gtacgtaatt tgtctaataa gggaacgcaa
    71341 ttctcacaaa tgcgcccaac taagggagtt cacttggtag tggattcaag caaaatcaag
    71401 gtttcacagc cagtttactt cgacacaggt ttgggtgacg gtcgtatggt ctttgttctc
    71461 ccacgtgaaa acaagactta ctttggtaca actgatacag actacacagg tgatttggag
    71521 catccaaaag taactcaaga agatgtagat tatctacttg gcattgtcaa caaccgcttt
    71581 ccagaatcca acatcaccat tgatgatatc gaaagcaact gggcaggtct tcgtccattg
    71641 attgcaggga acagtgcctc tgactataat ggtggaaata acggtaccat cagtgatgaa
    71701 agctttgaca acttgattgc gactgttgaa tcttatctct ccaaagaaaa aacacgtgaa
    71761 gatgttgagt ctgctgtcag caagcttgaa agtagcacat ctgagaaata tttggatcca
    71821 tctgcagttt ctcgtgggtc tagcttggac cgtgatgaca atggtctttt gactcttgct
    71881 ggcggtaaaa tcacagacta ccgtaagatg gctgaaggag ctatggagcg cgtggttgac
    71941 atcctcaaag cagaatttga ccgtagcttt aaattgatca attctaaaac ttaccctgtt
    72001 tcaggtggag aattgaaccc agcaaatgtg gattcagaaa tcgaagcctt tgcgcaactt
    72061 ggagtatcac gtggtttgga tagcaaggaa gctcactatc tggcaaatct ttacggttca
    72121 aatgcaccga aagtctttgc acttgctcac agcttggaac aagcgccagg tcttagcttg
    72181 gcagacacct tgtcccttca ctatgcaatg cgcaatgagt tgactcttag cccagttgac
    72241 ttccttcttc gtcgtaccaa tcacatgctc tttatgcgtg atagcttgga tagtatcgtt
    72301 gagccaattt tggatgaaat gggacgattc tatgactgga cagaagaaga aaaagcaact
    72361 taccgtgctg atgtaaaagc agctcttgct caaaacgact tagcagaatt aaaaaattaa
    72421 gaaaaaataa aagaggtgga gggtagcaat ccttgtcgcc cgcccctttt ttaatggaga
    72481 cagaaaaatg atgagtgaat tatttggaga atttttaggg actttaatcc tgattcttct
    72541 aggaaatggt gttgttgcag gtgtggttct tccaaaaacc aagagcaaca gtgcaggttg
    72601 gattgtgatt actatgggtt gggggattgc agttgcggtt gcagtatttg tatctggaaa
    72661 actcagccca gctcatttaa atccagctgt gacagttggt gtagctttaa aaggtgactt
    72721 gccttgggct tccgttttgc cttatatctt agcccagttc gcaggggcta tgctgggtca
    72781 gattttggtt tggttgcaat tcaaacctca ctatgaggca gaagaaaatg caggcaatat
    72841 cctggcaacc ttcagtactg gaccagccat caaggatact gtatcaaact tgattagcga
    72901 aatccttgga acctttgttt tggtgttgac aatctttgct ttgggtcttt acgattttca
    72961 ggcaggtatc ggaacctttg cagtgggaac tttgattgtc ggtatcggtc tatcactagg
    73021 tgggacaaca ggttatgcct tgaacccagc tcgtgacctt ggacctcgta tcatgcacag
    73081 catcttgcca attccaaaca agggagacgg agactggtct tacgcttgga ttcctgttgt
    73141 aggccctgtt atcggagcag ccttggcagt gcttgtattc tcacttttct agtttatact
    73201 cttcgaaaat caaattcaaa ccacgtcagc gtcgccttac cgtactcaag tacagcttgc
    73261 ggctagcttc ctagtttgct ctttgatttt cattgagtat tagaaaacaa ttatgttgat
    73321 agagcttggg caagagccca atttcagcaa aaaatgaagt aaatcttctc ataataaaac
    73381 gcatcatatc aagcacgaaa attccacgag gtcaactaca gtcagaaagc tgaacaacaa
    73441 gccaaaacgc ccaaaaaagg cggcaaaaag caagcacctg caagcaacgt gccgaaatgg
    73501 tcaaatcctg attatgtcaa cgaattagac ccaaaaatcg ttgatatgct agtagaattt
    73561 cacaagtcac aaggcacttt ggaaactccc gaggcgcaag cagaaatcgc ccaaaaacgt
    73621 gaagaaatcg agcaaaggag agctgagctt gaggataaaa aacaagagct tttgaaccgc
    73681 ttgaacaaat agagtttcgc aagtattatg cttacaaatt acttgagcaa ttaactaaaa
    73741 tataaaccct gcctttatat ctaggcaggg tttatatttt agaaattcac gtaggttgtt
    73801 acggttttta catacccagt atagtttgag tttctatagt attcagtgat aaacttccat
    73861 tttctttgag caacatggat ataagtactt gttatgtagt atggatatgg gctttgtgaa
    73921 tccaagtaag actgataagc ttgtatacca aaatatgctc caccaattat tgcaccccat
    73981 ggacccccca ataaagcacc tatcctacca atcatataac tgattccagc accagtcatg
    74041 aagttagcga atgtgttagc ttgtttattc ccatgtattg tgttgacgta attccaaaca
    74101 ttaggatcgt atgatctaaa agatatattt aggtcgattt cattcttttg ataagccata
    74161 taaaatgccc cattgatata gacgccgtca gcacgtcgtt caatagtgtc tacacttcca
    74221 tctggattga caacctcaag aacttcatcg cttaaaatat ttacttgcgt atctccgaac
    74281 cgcactgatg agccattctc aaactgagcc tcaccagata caactttaga gtttgccgat
    74341 aagctatcat cagcaaaaac aacaagcgac ggggaaatgc tagacataca gaaaacagac
    74401 ataactagca aacacatgca tttaaacatc ttagacataa cggaaactcc tttgtatttt
    74461 tgattttttt caacttttat tatacaataa aaccaaataa aaagaaagcg gtaacaatat
    74521 gcttaatgcg aaaatttttt atatattttt atgtttgatc gttatcgaaa ctacaggctt
    74581 gttgttgttg aaaagaggtc tcgaaatggg ttatttagac acagaagcta ttatcctcgc
    74641 agttttttca tttgcttttt acaacctatg ttcattcgct tgggtctgct ctacaataaa
    74701 aaacaataaa aaataaatag acgtattttc aaaaaaaaaa aaaaaaatgc atatttatct
    74761 tagcaaaacg acgatttaaa tcgtcgtttt tttgtagtac gacgggcatg tcgtatatct
    74821 gaggtgtaag tcctcggtgg gcacctgcta ccggtgaacc caatagcgat tcccaagcct
    74881 gactatcgtg aggtagcagg gagaggaagg gatagcgaaa tcgtggctct acgaacagga
    74941 acgtgatagt aaggcgtata tagcggataa ggaggcttca aactctaaag tccaaaaagg
    75001 tagtcgtaac ctatatgtgt aaatcacgag agtaattgaa ttcggactaa ggtttgtgtg
    75061 aaaaagataa atctttctag agtctaaaga ctctgcgtca gatttcctat tttcactgta
    75121 accttttaac gtcctcatat cttgtataaa cgaggaaaga tgtacgactt atcccgtgag
    75181 gtttcatgag cgctgaaagc gtagtaacaa cgaatcatga gaagtcagcc gagcccatag
    75241 tagtgaggaa acttccgtaa tggaagtgga gcgaaggggt gaacaactaa tcgaagtaat
    75301 cctacttcac ttgtgtctgt aaaatgagtg gtctgataga actggacttt gacacgtaat
    75361 gactagatga aggttcacca atataagatg tccctcaggc accaaaacaa gaaaggaata
    75421 cgcacatgtc aaaactgcta gataagatat tatcacgcga aaatatgctg gaagcctaca
    75481 atcaagtaaa atccaataaa ggctcagctg ggattgatgg aatgactatc gaagagatgg
    75541 ataattatct cagacaaaac tggcgcttga ctaaggaact gataaaacag agaaaatata
    75601 agcctcaacc agttcttaaa gttgagatac ctaaaccaga cggaggcatc cgtcaactag
    75661 gaattccaac agttatggat agaatgattc aacaggccat tgtccaagtc atgagcccca
    75721 tttgtgaacc ccatttctca gatacgagtt atggtttcag accaaatagg tcatgtgaaa
    75781 aagccatcat gaagctctta gaatacttaa atgacggcta tgagtggata gtggatatag
    75841 acctagagaa atttttcgat acagttcctc aagatagatt gatgtcctta gtacataaca
    75901 ttatcgaaga cggagatacg gaatccttga ttcgtaagta tcttcattca ggtgttatca
    75961 ttaatggtca acgttataaa acactagttg gtacaccaca gggaggaaat ttatctcctc
    76021 tcttatccaa tatcatgctt aatgaattgg acaaggaatt agaaaagagg ggacttcgat
    76081 ttgtgcgcta cgcagatgat tgtgtgatta cggtcggaag cgaggcagcc tctaagcgtg
    76141 tgatgtattc agtcagtcgt tttattgaga aacggctagg tttgaaagta aacatgacca
    76201 agactaagat taccagacca agagagttga aatatctagg ttttgggttc tggaaatcat
    76261 cagatggttg gaaaagccgt ccacatcaag atagtgttcg gagatttaag tttaaattga
    76321 agaaactaac acagaggaaa tggagtatag acctaacaag acgtattgag caactgaatt
    76381 tgtctattcg aggatggata aactatttct cattgggaaa tatgaaaagt atagtcgcca
    76441 gcatagatga gcgcttgcgt actcgcctac gagtgattat ctggaagcaa tggaagaaga
    76501 aatcgagacg attatgggga ttgcttaagt taggagttcc taaatggata gcagataagg
    76561 tatctggctg gggcgaccat tatcaattag tagctcagaa gtcggtactt aaacgtgcta
    76621 tatcaaaacc agtcctggaa aaacgtggac tggtttcgtg tttggattat taccttgaac
    76681 gacatgcgtt aaaagttagt tgaaccgccg tatgccgaac ggcacgtacg gtggtgtgag
    76741 aggggctaga gattatcccc tactcgatta actcccctga aatttatttt aattatgcaa
    76801 atttcacgta tttttgatgc tgagacgacg atcctgggaa cttttcagat atttttttga
    76861 ctatctaaat ctatcattag aaaagcttag agcgccaaag gatttgagcg tttttctgat
    76921 ttttaagact ttttccagtc tctttttcga ttgaagatgt aattattcta ctaactaact
    76981 aacttcttag tactagccaa caacgataat cataattcct cctaaaatta ggaataataa
    77041 aggcaatagt ttttgttttt tcatgtaaaa aacctcactt ttgttttctg ctattttatg
    77101 ctaaaatatt aaaaatcaaa tttaattcca aagtttgtaa ctaaaggggg agcgctacat
    77161 gtctaattca tttgtcaagt tgttagtctc tcaattattt gcaaatttag cagatatttt
    77221 ctttagagta acaatcattg ctaacatata cattatttca aaatcagtaa ttgccacatc
    77281 actagttcct atcttaatag gaatatcctc ttttgttgcg agtcttttag ttccgttggt
    77341 tactaaaagg ttagcgctaa atagggtttt atctttatct caatttggaa agactatatt
    77401 attggcgata ctggtaggaa tgtttaccgt aatgcaatcc gtagcgcctt tggtgaccta
    77461 tctatttgtt gttgcaattt ccatactaga tggttttgca gcacccgttt cctatgctat
    77521 tgtgccacgc tatgcgaccg atttgggtaa ggctaattca gccttatcaa tgactggtga
    77581 agctgttcaa ttgataggtt ggggattagg tggactcttg tttgcaacaa ttggtctgtt
    77641 acctaccacg tttatcattt tagtcttgta tatcatttct agctttctga tgttatttct
    77701 tcctaacgct gaagtggagg tgttagagtc agaaactaat cttgaaattt tgctcaaagg
    77761 ttggaagtta gttgctagaa atcctagatt aagacttttt gtatcagcaa atttattgga
    77821 aattttttca aatacgattt gggtttcttc cattatactt gtttttgtaa cggagttatt
    77881 aaataaaacg gaaagttact ggggatattc taatacagca tactctattg gtattataat
    77941 tagtggctta attgctttta ggctatctga aaagttcctt gctgctaaat gggaaagtat
    78001 tctttttcct cttgtagcta tggcaatagt gacactgact attctatatt ttccaaacgc
    78061 acagatgttt ttattatttt cagctttagt tggtatgtta tcgcaactaa aagaagttcc
    78121 tgaaagtgta tttcttcagg aaacagtaga ggaaaatcat ttagttaatg tctattccgt
    78181 tcttgaagtg atttctacat tagcattttc agtatttgtt ttgctaatga gctatattac
    78241 tgagagtttt ggtattagca tcagtttttg gctatcagcc atttgtctga tgatagaagc
    78301 tattttaatt tatatcagac gagattattt taaatgagag agtggttaaa aagtctttaa
    78361 aaatcagaaa agcgcatagt atcaggtgtt gaaaaaactt gatattgtgt gttttattat
    78421 gggaatattt acttcattgt ctcctgaaat ggagttttga agcaggatca ctctatttga
    78481 aaatatacat agaaaaactg tataatcctt aaaataatct gaaatctatt ggaaacatac
    78541 ggtaaacaat tgaaaagata ctatataaag tggtacaatg gtagaaaaat aagctagtaa
    78601 gaatcactct tattttagcg aaaaattaca gaaatgaatg gtttttcttg atgaaacaga
    78661 gaaaagaatt gtacctcttt cttggtcgga cagccttgta ttttcttatc tttctagggc
    78721 tgctttactt ctttagctat cttggtcagg gtcaaggaag ctttatctat aatgaatttt
    78781 aacttgaagg agaatcccta ttgtgtcaaa taaaccaata gcagatatga ttgaaaccat
    78841 tgagcatttt gctcagacac agcctagcta tcctgtctat aatgttttgg ggcaggaaca
    78901 cacttatggc gatttaaagg ctgattcgga tagtttggct gcagtcattg accaactagg
    78961 cttgcctgag aagtctcctg tggttgtttt tggtggccaa gaatatgaaa tgttggcaac
    79021 ctttgtagcg ctgactaagt caggtcatgc ctacattcca attgatagcc attcggcctt
    79081 ggagcgagtt tcagctattt tagaagtagc agagccaagc ttgattattg ccatttcagc
    79141 ctttcccttg gagcaggttt ttacaccaat gataaatcta gctcaggttc aagaagcctt
    79201 tgcccaaggg aataactatg aaatcacgca tccagtcaag ggagatgata attactacat
    79261 tatctttact tctggtacga ctggtaagcc taagggagtg cagatttcac atgataatct
    79321 cctcagcttt acaaactgga tgattacgga taaggaattt gcgacaccga gtcgtccgca
    79381 aatgctggca cagccacctt attcttttga cttgtctgtc atgtattggg caccgacctt
    79441 ggcacttggt ggtacgcttt tcactcttcc ttcagtcatc actcaggact ttaagcaact
    79501 ctttgcggct atcttttcat tgccaatcgc tatctggaca tcaacaccat cctttgcaga
    79561 tatggccatg ttgtctgaat acttcaacag tgagaaaatg cctggaatca cgcatttcta
    79621 ctttgatggt gaagaattga cggtcaaaac agctcaaaaa ctgcgcgagc gtttcccaaa
    79681 tgcccgtatc atcaatgctt acggcccaac agaagcgaca gtagctctgt cagcagttgc
    79741 cgtgacagac gagatgttag cgactctcaa acgcctacca atcggctata ccaaggctga
    79801 ttctccaacc tttatcattg acgaggaagg aaataaactg ccaaatggtg agcagggaga
    79861 aatcattgtt tctgggccag ctgtttcaaa aggttatatg aacaatcctg aaaaaacagc
    79921 agaagccttc tttgagtttg aagatctgcc agcctatcac acaggcgatg tgggaaccat
    79981 gacagatgag ggcttgcttc tctacggcgg acgcatggac ttccagatta agtttaacgg
    80041 ttaccgcatt gagttagaag atgtctctca aaacctcaac aagtctcgct ttatcgaatc
    80101 tgctgtcgca gtaccgcgct ataacaagga ccacaaggta caaaatctat tggcttatgt
    80161 catcttaaaa gacggtgttc gtgagcagtt tgagcgagat atcgatatta ccaaggccat
    80221 caaggaagac ctgacagaca tcatgatgtc ctatatgatg ccatctaaat tcctttaccg
    80281 agacagtttg ccactaactc caaatggaaa gattgacatc aaaggattga ttaacgaggt
    80341 gaataagaga tgatggagtt ttttcaacag cttcctcatt tagagccata tggcaaacct
    80401 cagtattttg tttatgtgat tgctgcaacc ttgcccatct ttataggtct ctttttcaag
    80461 aaacgctttg cctggtatga agtgttggta agtctcttct ttattgtcac catgttggtg
    80521 ggtggaaaga ccaatcaact agctgccttg ggtatttacc tttgctggga aatattgctc
    80581 ctgcttttct acaagcatta tcgaaaaagc aaggatggca agtgggtctt ctacttagtt
    80641 agttttctgt ccctacttcc gattatcttt gtcaaggtgc aaccagctat caatggaacg
    80701 cagtctttgc ttgggttctt gggaatttct tacctgacct ttcgttcggt tggaattgtc
    80761 atcgagctga gagatggagt gattaaggat tttaccctct gggaattcct ccgtttcctt
    80821 ctcttcatgc caactttctc gagtggtcca atcgatcgct ttaagcgatt taatgaaaat
    80881 tatcaggcta ttcctgagcg agatgagttg atggatatgc tggatgaatc tgtccgctat
    80941 atcatgtggg gctttttgta taagtttatc ctagctcatg ttttaggaga gaccttacta
    81001 cctcctctga agaatttagc cttgcagtca ggtggcttct ttaatctcta tgccttggca
    81061 gttatgtata cttttggtct ggagctcttc tttgactttg caggttattc tatgtttgct
    81121 ttggccatct caaacttgat gggaatccgt agccctatca actttaacaa gcccttttta
    81181 tcaagggatt taaaggagtt ttggaatcgc tggcatatga gtctgtcctt ctggttccgt
    81241 gactttgtct ttatgcgaat ggtgatggtg ttaaccagaa agaaagtctt taaaaatcgt
    81301 aatgtaacct caagcatggc ctacattgta aatatgctga ttatgggatt ttggcatggc
    81361 gtgacctggt actatatcgc ctatggactc tttcatggac taggcttggt catcaatgat
    81421 gcctgggttc gcaagaaaaa aacgctcaat aaggaacgga aaaaagcagg gaaggctgcc
    81481 ctacctgaga atcgctggat tcagtttctt ggcatggttg tcactttcca tgttgtcatg
    81541 ttgtcattct taatcttttc tggattcttg aataatctat ggtttaaaaa ataaaaggaa
    81601 ataaaatatg gatatcaaat cagaagttat tgaaattatt gatgagttgt ttatggaaga
    81661 tgtttctgac atgatggatg aagatctttt tgatgcaggt gtcttggata gtatgggaac
    81721 ggttgagttg attgtggaga ttgagaaccg ttttgacatt cgtgtccctg taacagagtt
    81781 tggtcgtgac gactggaata cagctaataa aatcatagct ggtattgtgg agctacaaaa
    81841 tgcttaaacg cttatggatg atcttcggac cggtcttgat cgctggtttg ttggtttttc
    81901 tgctcatttt cttttatcct actgagatgc atcataatct aggagctgaa aagcgttcag
    81961 cagtggctac tactatcgat agttttaagg agcgaagtca aaaagtcaga gcactatctg
    82021 atccaaatgt gcgttttgtt cccttctttg gctctagtga atggcttcgt tttgacggtg
    82081 ctcatcctgc ggtattagct gagaaataca atcgttccta ccgtccttat cttttaggac
    82141 aggggggagc tgcatcgctt aaccaatatt ttggaatgca acagatgtta ccacagctgg
    82201 agaataaaca agttgtgtat gttatctcac ctcagtggtt cagtaaaaat ggctatgatc
    82261 cagcagcctt ccagcagtat tttaatggag accagttgac tagttttctg aaacatcaat
    82321 ctggggatca ggctagtcaa tatgcagcga ctcgcttact gcaacagttc ccaaacgtag
    82381 ctatgaagga cctggttcag aagttggcaa gtaaaggaga attgtcgaca gcagacaatg
    82441 aaatgattga attattggct cgttttaatg aacgccaagc ctcctttttt ggtcagtttt
    82501 cggttagagg ctatgttaac tacgataagc atgtagctaa gtatttaaaa atcttgccag
    82561 accagttttc ttatcaagca atagaagatg ttgtcaaagc agatgctgaa aaaaatactt
    82621 ccaataatga gatgggaatg gaaaattatt tctataatga gcagatcaag aaggatttga
    82681 agaaattaaa ggattctcag aaaagcttta cctatctcaa gtcgccagag tataatgact
    82741 tgcagttggt tttaacacag ttttctaaat ctaaggtaaa cccgattttt atcattccac
    82801 ctgttaataa aaaatggatg gactatgctg gtctacgaga ggatatgtac caacaaacgg
    82861 tgcagaagat tcgctaccag ttagaaagtc aaggttttac caatatagca gatttttcta
    82921 aggacggcgg ggagcctttc tttatgaagg acaccattca ccttggttgg ttgggttggt
    82981 tggcttttga caaggcagtt gatcctttcc tatccaatcc cacaccagct ccgacttacc
    83041 atctgaatga gcgctttttc agcaaagatt gggcgactta tgatggagat gtcaaagaat
    83101 ttcaatagat aatataatat agaagagttc aagaatgaaa ctagttttca cgttttttct
    83161 tgactctttt tttgcttgtg atataattaa ctggtaaaca aaatgtcaaa gaatagtatt
    83221 tttctcttaa aaaagagaag tctaaaagga aaggagtcag atatgagaca gctagcaaag
    83281 gatatcaatg cttttttgaa tgaggtgatt ttgcaggcgg aaaatcagca tgaaatccta
    83341 ataggtcatt gcactagcga ggtggccctg accaatactc aggagcatat tcttatgctc
    83401 ttgtcagagg aatctttaac aaattcagaa ttggcccgtc gtctcaatgt cagtcaggcg
    83461 gcagttacca aggccattaa gtctttggtc aaggaaggga tgttggaaac atctaaagat
    83521 tctaaagatg cgcgtgtgat tttttatcag ttgactgact tggctcgtcc aatcgctgag
    83581 gagcaccacc atcaccatga gcatacactt ttaacctatg aacaagtggc gactcagttt
    83641 actccaaatg aacaaaaagt gattcagcgg tttttgactg ctttagtagg agaaatcaaa
    83701 taatgagata tattacggta gaggatttgt ccttctatta tgataaggag cctgttcttg
    83761 aacatatcaa ttatagtgtt gatagtgggg aatttgttac cttgactggg gaaaatggag
    83821 cggctaagac gacgctcatc aaggccagtc ttggaattct gcaaccacgc attggaaagg
    83881 tggctatttc aaagacaaat acgcaaggta agaaattgag aatagcctat cttcctcaac
    83941 aaattgccag ttttaatgct ggttttccaa gtacggtcta tgaatttgtc aagtcgggtc
    84001 gctatccgag aaaaggctgg ttccgtcgtt tgaatgctca tgatgaggag catatcaagg
    84061 ctagtctgga ctcagttggc atgtgggaac atcgagacaa acgcttgggg tctctatctg
    84121 ggggacaaaa gcagcgagcg gtgattgcgc gtatgtttgc ttctgaccct gatgtgttta
    84181 tcctagacga gccgacaacg gggatggatg caggaagtaa aaatgaattt tacgaactca
    84241 tgcaccacag cgcccatcat catggcaagg ctgttttgat gattacccat gaccctgaag
    84301 aagttaagga ttatgcggat cgcaatattc atctagtccg taaccaagac tcgccatggc
    84361 gttgtttcaa tgttcatgag aatggccagg aggtgggcca tgcttagttt attatcttac
    84421 gactttatac aacgcgcctt tttggcggtt attgctatga gtcttttctc accggtattg
    84481 ggaaccttcc tcatcttgcg tcgtcagagt ttgatgagtg atacccttag ccacgtctca
    84541 ctttcaggtg tagcctttgg tctggttttg gggatttctc caactgtttc tactattgcc
    84601 attgtcttga ttgcggcggt ctttctggag tatctccgta cggtttacaa gagctttatg
    84661 gaaatcggga cagctatcct catgtcaaca ggtctggctg tttctctgat tgtcatgagc
    84721 aagggtaaaa gctcgagttc aatgagtttg gaccaatatc tctttggttc gatcgtgact
    84781 atcagtgaag aacaggtcat ttccctcttt gtcattgcgg cggttgtttt gattttgacc
    84841 tttctctttc ttcgtcctat gtatatctta acttttgacg aagatacggc ctttgtggat
    84901 ggcttgccag ttcgtaccat gtccattctt tttaacatgg tgacaggggt ggctattgcc
    84961 cttatgattc ctgcagcagg agctcttctg gtatcgacca ttatggtctt gccagctagt
    85021 attgccctgc gtctggggaa aaactttaaa tcggttatgc tgcttgccag tgcgattggc
    85081 tttttgggaa tggtagcagg actttacatt tcctactatg cagaaacacc tgcaagtgca
    85141 agtattacca ttatttttgt aactgtcttt atactaatca gtttagtaag acgttttatc
    85201 aaataggaga cgaacgtgaa aaaaattagc ttattactag ccagtctatg tgccttgttt
    85261 ttagtggctt gttccaatca aaaacaggca gatggtaaac tcaatatcgt gacaaccttt
    85321 taccctgtct atgaatttac caagcaagtt gcaggagata cggctaatgt agaactccta
    85381 atcggtgctg ggacagaacc tcatgaatac gaaccatctg ccaaggcagt tgccaaaatc
    85441 caagatgcag ataccttcgt ttatgaaaat gaaaacatgg aaacatgggt acctaaattg
    85501 ctagatacct tggataagaa aaaagtgaaa accatcaagg cgacaggcga tatgttgctc
    85561 ttgccaggtg gcgaggaaga agagggagac catgaccatg gagaagaagg tcatcaccat
    85621 gagtttgacc cccatgtttg gttatcacca gttcgtgcca ttaaactagt agagcacatt
    85681 cgtgccagct tgtcagcaga ttatcctgat aaaaaagaga cctttgagaa gaatgcagct
    85741 gcctatatcg aaaaattgca agccttggat aaggcttacg cagaaggctt gtctcaagca
    85801 aaacaaaaga gctttgtgac tcaacacgca gcctttaact atcttgcctt ggactatgga
    85861 ctcaaacaag tcgcaatctc aggcctttct ccagatgcag agccatcagc tgctcgcttg
    85921 gcagaattga cagagtatgt caagaaaaat aaaatcgcct atatctattt tgaagaaaat
    85981 gcctcacaag cccttgctaa cacactttca aaagaagcag gtgtcaaaac tgatgtcctc
    86041 aatcctttag aaagtctgac agaagaggac accaaggctg gagaaaacta catttccgtg
    86101 atggagaaaa acctcaaggc tttgaaacaa acaacagacc aagaaggccc agcaatcgaa
    86161 cctgaaaagg cagaggatac caagacagtc caaaatggtt acttcgagga tgcagctgtc
    86221 aaggaccgca ccttgagtga ctatgcaggt aactggcaat cagtttatcc tttccttgaa
    86281 gacggcacgt ttgaccaagt ctttgactac aaggctaagt tgactggtaa gatgacccag
    86341 gctgagtaca aggcttacta tacaaaaggc tatcagacag atgtgactaa gattaacatt
    86401 actgataata ctatggaatt tgttcaaggt ggacaaagca agaaatacac ttacaagtat
    86461 gtcggtaaga aaattttgac ttacaagaaa ggcaatcgtg gcgtgcgttt cctctttgaa
    86521 gccacagatg ctgacgctgg acaattcaag tatgttcagt ttagtgacca caatatcgcc
    86581 ccagttaagg cagaacattt ccatatcttt tttggaggta caagccaaga aactctattt
    86641 gaagaaatgg ataattggcc aacctactat ccagataacc tatctggcca agaaatcgcc
    86701 caagaaatgt tggcgcattg atgagaaatc gactagttca taagagctag tcggtttttt
    86761 gatactagat ggctaacttc attatagacc tttcagaact aagggaacct gaaaaaataa
    86821 ataaaactct tgaaatatct gggcttatat gctagaatgt agttagtgta taaggttcat
    86881 tagaacacca aagcccctaa ctagtgccat agttaagggc ttttttgacg tatcttagcg
    86941 atttaacggg tgtttatagg ctagtcattc ggtctacttc ttaccatcta gccatttgca
    87001 gacgaaatac aagataattc cagctataac atctgctata atagtaagag caagctctgg
    87061 tataaggctc attagtttca cctcctctca cgaacccata ggaacgtaat cggtaaccga
    87121 tgacaaaaat agtataccac actaaattta gatcatcaac ctcacttaat gcttgaacta
    87181 ttgtagatta tatgctaaaa tgtagttaat tgataaggtt cattagaaca ccaaagcccc
    87241 taactatggc cgtagttaag ggcttttttg acgtatctta gagatttaac gggtgtttat
    87301 aggctagtca gtcggtctac tccttactat ctagccatct gcagacgaaa tacaagataa
    87361 ttccagctat aacatccgct ataatagtaa gagcgagctc tatgataagg ctcattagtt
    87421 tcacctcctc tcacgaaccc ataggaacgt aatcggtaac cgatgacaaa aatagtatac
    87481 cacaatacat ttagatcatc aaggtcactt aattcttgaa atatagggtc taggcgacaa
    87541 agtctttaaa atcagaaaaa cgcataatat caggtgtgca aaaacttgat actatgcgtt
    87601 ttattgtggg aaggtttact ccattttctc ctgaaattga gtttttgtcc agcctctgtt
    87661 tttggggttg ctaagaaaat aatgtcatgt ggtgaatatt tgtaaatcag tcagcagaca
    87721 gaacgatact cttcgaaaat ctcttcacat catgtcagct tcgtctttcc gtatatatgt
    87781 gactgacttc atcagttcta tctacaacct caaaacagtg tttcgagctg acttgatcaa
    87841 ttttcaaatc tgtactgtga gcaagctgag actagcttcc tatttgattt tcattgaata
    87901 tcagaaaccc attctccatc aaataattcg actgcgtcta ataatttttg atctggcacg
    87961 gtgtctgaaa taaaggttgt gtatttggag aggggattaa ttttaaaaaa tccagtcttg
    88021 taaaatttag aactatcaat cagtaagatg gtttcatggg ctttgtcaat aatattcttt
    88081 tttgaaatag cttggctgag agaagcttca taaacatatt ggtcatcaat acctcttgct
    88141 gaacaaaatg ctaaatcgat attaaaatga tctaataaag aattttcctt atcgtaattg
    88201 accacggaac aggattgatg tttgacctcg ccagatgtga taaagatttt ggagctatct
    88261 ttaacagttt cagatagggt ttgtgcagta tgtaaaccat ttgtaaaaat aatcaaatta
    88321 tcaagttcag aaagataggg acaaagttcg tagacagtcg tactggaatc cagataaaca
    88381 cacatacctg accgaataaa gtctttagcg agactagcga ttagtctttt ttgcctagta
    88441 ctttctcctt cccgtatttg atgagaaagt tcaattgtgt tcatagagga cagggtcacg
    88501 tatccgtgct ttcttttgat aagaccttga ttttctaaga aaattaaatc acgacgtaag
    88561 gtacttgtgc tggagaaagt gatttctgcc agctctttta cggcaattct ttttttcttt
    88621 ttaataattt caatcaattc aagtacacgt tcatctttta tcataagctc ctcctaattt
    88681 atcatttcaa ctatattata gcacaaattg gaggaatttg aattattttt atgaatattg
    88741 ggttaacatt tgaacattat tcaagtaagc gttcacatat tgaaaaaata aaacgtgggg
    88801 attataataa agttaatcaa ggacgaagag agaagaaaaa tggaagcggt tttagcaata
    88861 gatttaggtg cgacttctgg aagagcaatc gttggttacc tttctgaaaa taaactagta
    88921 atggaagaaa taaatcgctt ttctaatcta cctattagag taaaagggca tttatcttgg
    88981 gatattgact ttctactagc taaaattctt gaaagtatcc gcttggctaa tactagttac
    89041 aagattttat ctatcggtat tgacacatgg ggagttgatt ttggactggt tgataatgaa
    89101 ggtaagctgt tattacaacc tgttcattat cgtgatgaaa gaacaaaggg agtgttaaag
    89161 gaaatatctg aaatgactga attagaaaaa ctgtattcag agacaggaaa tcagattatg
    89221 gagataaata ccttgtttca actctttaag gcacgtcaag aatctcctga ctctttctat
    89281 aagaccaata agattctttt aatgccagat ttgtttaatt atctcttgac aggtaagttt
    89341 gctacagaaa aaagcattgc ttcaacaact caattatttg atcctaggag tcaaaactgg
    89401 aatcagaata tcttaaaact atttgaattg gattcatctt tacttcctga gattgtttca
    89461 gagggaaatg ttcttggaag gataaaaaag gagtatggtt taggcgatat tcctgttgtg
    89521 aatgtttgta gtcatgatac agcaagcgcg attgtctcag tacctaagac agaaggtagt
    89581 ttatttattt catcaggtac ttggtctttg gttggagtgg aacttacttc accgcttctt
    89641 actaccgaat ccttcagtta tggatttaca aatgaagtcg gtaaagatgg agtgattaca
    89701 tttctgaaga attgtacagg gttgtggatc atagaggaac taagacgttc atttgaacga
    89761 agagggaaag cctattcttt tgatgatatt aggacaatgg tggagaaaga aaaagaaaat
    89821 cttcctctga ttgatactga atcaactgaa tttgcaacag aatctgatat gcacaagact
    89881 ttgacagaat atctagctta tcatcatgaa actagagagt ggacagatgg acaactattt
    89941 aagattgttt atgaaagcct agctgaaacg tataggaaag cgatagagtt actagaagaa
    90001 ctaactcata aggtttataa gaggatatat gtgattggag gaggtgctag agccagttac
    90061 tttaaccaaa tgattgctga tagaactggt aaagaggttc ttacaggttt gactgaggct
    90121 acagctgtgg ggaatattgt tgtgcagctc atagctatgg gacaattaaa agggatggaa
    90181 gaagctcacc atgttattga ggagtttcta caattagaga gttattactc ccaaaagaat
    90241 taaaaagatt gagagtttgt aaatttgcct ccctccccct tcttaagttt tgtacaagaa
    90301 ggggggataa ttggtgaatt gaaaaatatt tagtgttttg atatgaggag gacaagaatg
    90361 tcagatgtaa aacaagaatt aattaagtat ggcaagaagc tagtagaaac agatttgacg
    90421 aaaggaacag gtgggaatct cagtgttttc gatcgtgaaa aacaattgat ggcaattacc
    90481 ccgtcgggta ttgatttctt tgaaatcaaa gaatccgata ttgtagtgat ggatattaat
    90541 ggaaatgttg tagagggaga acgcttgcca tctagcgaat ggtatatgca tttgattcaa
    90601 tatcaaactc gtgatgatat cgatgcaatt atccatgctc atacaactta tgcaacagta
    90661 ttagcttgtc tcagagaacc acttccggct agtcattata tgattgcagt ggcagggaaa
    90721 gatgttcggg tagctgagta tgcaacatat ggtacgaaag aattggctgt gaatgcagct
    90781 aaagcaatgg aaggtcgtag agcagtttta ctagcgaatc atggaatttt agcaggtgca
    90841 caaaatttat tgaatgcatt taatattgtt gaagaagttg aatattgtgc aaaaatttat
    90901 tgtttagcta agaattttgg agagccagta gttcttcctg atgaggagat ggatttaatg
    90961 gcagaaaaat ttaaaacata cggtcagaga aaatagggag gatattaatg ttaaaacata
    91021 taccgaaaaa tatttctcca gatttattga agactttaat ggaaatggga catggagatg
    91081 aaatagtatt agctgacgcg aattatcctt ctgcctcatg tgcaaataag ctaattcgtt
    91141 gtgatggcgt aaatattcca gaattattag attccattct gtatttaatg ccattagata
    91201 gttacgtcga tagttcaatt cagtttatga acgttgtttc gggtgatgat attcctaaga
    91261 tatggggtac ctatagacag atgattgaag gtcatggtac agatcttaaa acgattactt
    91321 atcttagaag agaagacttt tatgaacgta gtaagaaagc ttatgctatt gttgctacag
    91381 gagaaacttc actttatgct aatattatcc ttaagaaagg agtagttgtt gaaagagaaa
    91441 atgtttaata gaggaatttt agttgccagt catggtaatt ttgctagcgg agctctcatg
    91501 accgcagaaa tgtttgttgg tgagacaaca aatgatagag ttaggacatt aggtttgatg
    91561 cctggagaga atattgtaga gtttgaacat tattttaaaa atcaagtaaa tgaactgtta
    91621 gactcaaatc aagaggttat cgttttgact gacttgattg gaggaagtcc taataatgtg
    91681 gctttgtcac ggtttttaaa tttggattca gttgatattg taacagggtt taatatccct
    91741 ctcctagtgg aattaatatc aagttatgat tcaaaaatca atttagaaga aattgttcaa
    91801 aatgctcaaa atagtttgtt taatgttaaa caacaactta acgtagagga ggaagaggat
    91861 ttatgtctat agagtttgtt cgtattgatg accgtctggt acatggtcaa gttgtcacta
    91921 cgtggctaaa aaagtatgat attgagcaag ttatcattgt taatgatcgc atctcagaag
    91981 ataaaacacg acaatctatt ttaaagattt ctgcaccggt aggtttaaaa attgttttct
    92041 ttagtgtaaa acggtttgtg gaagttttaa actctgtgcc aataaaaaag agaacaatgc
    92101 tgatatatac aaatccaaaa gatgtgtatg attctattga aggaaattta aaattggagt
    92161 acctcaatgt aggacagatg agtaaaacgg aggaaaatga aaaggtaacg ggaggtgtag
    92221 ctctaggtga agaagacaaa tattatttta agaaaatagt tgataaggga acgagagttg
    92281 aaattcaaat ggttcctaat gataaagtta caatgttgga aaaattttta taaaaataat
    92341 ttaaggaggt acagtatatg ctattcacac aagcattact ggtgacatta gttgggatta
    92401 ttgccactat tgactataat ggaccgttat ttatgattca ccgtccgtta gttacaagtg
    92461 caatggttgg cttagtctta ggagatttca cccaaggtgt tcttattggt tcagctcttg
    92521 aattaacttg gctcggtgta acaggtattg gaggttacac tccaccagat actatttcag
    92581 gtgcgattat tggtactgca tttggtattt tatctggtca aggagaaact gctggtatcg
    92641 ctatagcagt tccaattgca gttgctaccc aacagttgga tgttcttgca aaaactttag
    92701 atgtttattt tgtgaaaaaa gctgataatg atgctaaaaa cggagattat tcaaagatcg
    92761 gtttttatca ttattcaagt ttggttttaa tcacgttatt taaaattgta ccaattttcc
    92821 tagctattat gcttggaggg gaatatgtgg cagacttgtt tgctaaggtt ccaccaatcg
    92881 ttatgcaggg acttaactct gcaggtgctt tactaccttc aattggtttt ggtatgcttt
    92941 taaatatgat gctcaagaaa aatatgtggg tattcttgtt gattggattc atttgttctg
    93001 tgtatggagg aatgtcaacc attgggatct cactagttgg tattgcggta gcatacttct
    93061 acgatatgat tggaagtaaa ccacaagaaa caacttcaag tagtgatgtt gaggaggatc
    93121 ttgatctatg atgaataata aagtaactaa agttgaactt aaaaaagttt tcaaacgaag
    93181 ttttatgtat ggttcttcat ggaactatga gagaatgcag aacctaggtt ttctatatac
    93241 aattcttcca gtattgaaaa aactataccc agacaaagat tcagcttctc ctgcaatgaa
    93301 acgtcacctt gagtttttca atactcatca aacagcggca ccatttattc ttggagttac
    93361 ttccgctatg gaagaacaag aaggaaatga aggtgcagct tcaattactg gtattaaagt
    93421 tggcttgatg gggccactgg ctggtctagg agatagtttg ttctggctga cactagttcc
    93481 tatctgtttt agtattggtg cgtcttattc taaagacggc ggtgctttag gtatctttat
    93541 cgccttaata ttgtttaata ttattaatat tcctgttaaa tatttcggtt tgaaatatgg
    93601 gtatactaag ggttctagtc ttatccaaga aaataataca aaaggaacat tgaatcgcgt
    93661 tacgagtatg gcgacagcat tagggctagt actagtgggt ggtttgattc catcaatggt
    93721 tggtattaat tttggattag aatttaagca gggggaactt gttatttctg ttcaagaaat
    93781 gattacaaaa ttaattccag gatttatccc tatggctttg actttattaa tgtgtaaatt
    93841 aattagaaaa ggaaagaatc cggttgtact aatctttagt gttatggcta ttggagttat
    93901 cctagttgtt ttaggaattt tgaagtagta gaaagtgtgg aggtggtatt tgggatatca
    93961 cctccatttt ggaagagagg taaagagtga aattatggta taagaaagct gcctcaaatt
    94021 ggaatgaagc cttgccgatt gggaacggtc atttaggtgg tatgatttat ggttcagcta
    94081 caaaagaatg tattcaacta aacgatgaga ctatttggta tagaggaaag tcagatagaa
    94141 ataatccaga ctcactattg catcttaaaa aaattcggga atatctttta gatggagaaa
    94201 ttcagaaagc cgaagaattg ataaagttaa caatgtttgc taccccaaga gatcaaagcc
    94261 actatgaatt acttggggaa ctttacattg agcatataga tattcagtct tgtgctcttt
    94321 cattgtatga aagagagcta gatttagata cagctatttc taatgttgtg tttgagccta
    94381 atagttgtaa tttacaaata aaaagagaat attttacgag ttttaataag aatattttat
    94441 gttgccgtat agtgtcatca gttcaaaaca cattaaattt aaacattaat ttgggtagaa
    94501 ataaacggtt taatgatgaa gtatctaaac tggattcaag tacaatttta atgtcggcct
    94561 ctgctggagg tagaaaaggt gttcagttta aagtagtatg tcattctaag gttacggatg
    94621 gtgaagtaag tgtattggga gagacaatag ttattcggaa tgctacagag gtatttcttt
    94681 atctcaaatc aatgacggat tattggggaa atatagatat ttcttctctt cagggagaat
    94741 ttagtagtat tgattacttt acagaaaaag atgaacatgt aaaaaaatat caggagcaat
    94801 ttaatagagt tgattttaaa ctagactata gtaaagattg tcttagcatt ccaacgaatc
    94861 tacttcttga aaacactaaa aagtatagta actacttgac taacttgtta tttcattatg
    94921 gaagatatct gttaatatcg tctagtcaac cgaatggttt acctgccaat cttcaaggaa
    94981 tatggtgtga tgaattaaat ccaatttggg gttctaaata tacgattaat attaatactc
    95041 aaatgaatta ttggatggta ggtccatgtg atttaccaga agtagaatat ccattatttg
    95101 atatgctcga aagaatgaga gaaccgggaa gactaaccgc taagaaaatg tatggagcta
    95161 gaggttttac agcacatcat aatacggatg gttttggcga tacggctccc caatctcatg
    95221 ccatgggggc tgcaatttgg gtattaacta ttccatggtt atgtactcat atttgggaac
    95281 actatttata tttccaagat gagcgtattc ttacggaaca ttttgaaatg ataaaagaag
    95341 catttctttt ctttgaagat tatttatttg aggtggatgg ctacttgatg acaggtccaa
    95401 gtgtctcacc ggaaaataaa tatcgcttaa aaaatggtat tgaaggaaat gcttgtctat
    95461 catctacaat tgataatcaa attctaagat atttttgtga ttcatgcatt ggcattgcaa
    95521 aacaattagg agacaattcg gattttatta gtcgtgtgaa ggagttaaaa aagaaactac
    95581 ctaaaacaaa aataggtagt aatgggcaaa tccaagaatg gttagaagat tatgaagaag
    95641 tagagcctgg gcatagacac atttcacctc tatttgggct ttatccttat aatgagattg
    95701 atattcataa aactccggaa ttagcagaag cagctaaaat cactatcaat aggagattat
    95761 caaacgctaa ttttttatct tcacaggaga gggagcaagc gattaataat tggttagtaa
    95821 gtggtttgca tgctagtaca caaacaggtt ggagtgctgc atggctgatt catttttttg
    95881 cgagactata tcaaggtgaa cctgcttata accagattaa tggtttgtta aataatgcga
    95941 ctcttggcaa tttatttctt gaccatccac catttcaaat tgatggtaat ttaggtttgg
    96001 tgagtggaat ttgtgaatta ttagtacaga gccatcataa ttggttatca ctaattccag
    96061 ctttaccttc tgcttggtca gaaggagaag tgaaaggttt cagagtaaga ggaggatata
    96121 aggtatcgtt tgcttggaaa aatggggata taacattcct aaaattggaa ggaggaaaca
    96181 aagatcaaaa agtaagagta agaatatatg gcaaaaatac tgatgtacaa aatattgaat
    96241 tggtatttaa ttcagaaaaa attattgagt taaattttta ggtataagtc atgaataaag
    96301 aaaaaataaa aagaaaatta atcacaatat tgtttgtatg tattgggatg ttatgttttg
    96361 gattgttagc aggagttaag gctgataatc gtgttcaaat gagaacgacg attaataatg
    96421 aatcgccatt gttgctttct ccgttgtatg gcaatgataa tggtaacgga ttatggtggg
    96481 ggaacacatt gaagggagca tgggaagcta ttcctgaaga tgtaaagcca tatgcagcga
    96541 ttgaacttca tcctgcaaaa gtctgtaaac caacaagttg tattccacga gatacgaaag
    96601 aattgagaga atggtatgtc aagatgttgg aggaagctca aagtctaaac attccagttt
    96661 tcttggttat tatgtcggct ggagagcgta atacagttcc tccagagtgg ttagatgaac
    96721 aattccaaaa gtatagtgtg ttaaaaggtg ttttaaatat tgagaattat tggatttaca
    96781 ataaccagtt agctccgcat agtgctaaat atttggaagt ttgtgccaaa tatggagcgc
    96841 attttatctg gcatgatcat gaaaaatggt tctgggaaac tattatgaat gatccgacat
    96901 tctttgaagc gagtcaaaaa tatcataaaa atttggtgtt ggcaactaaa aatacgccaa
    96961 taagagatga tgcgggtaca gattctatcg ttagtggatt ttggttgagt ggcttatgtg
    97021 ataactgggg ctcatcaaca gatacatgga aatagtggga aaaacattat acaaacacat
    97081 ttgaaactgg aagagctagg gatatgagat cctatgcatc ggaaccagaa tcaatgattg
    97141 ctatggaaat gatgaatgta tatactgggg gaggcacagt ttataatttc gaatgtgccg
    97201 cgtatacatt tatgacaaat gatgtaccaa ctccagcatt tactaaaggt attattcctt
    97261 tctttagaca tgctatacaa aatccagctc caagtaagga agaagttgta aatagaacaa
    97321 aagctgtatt ttggaatgga gaaggtagga ttagttcatt aaacggattt tatcaaggac
    97381 tttattcgaa tgatgaaaca atgcctttat ataataatgg gagatatcat attcttcctg
    97441 taatacatga gaaaattgat aaggaaaaga tttcatctat attccctaat gcaaaaattt
    97501 tgactaaaaa tagtgaggaa ttgtctagta aagtcaacta tttaaactcg ctttatccaa
    97561 aactttatga aggagatggg tatgctcagc gtgtaggtaa ttcctggtat atttataata
    97621 gtaatgctaa tatcaataaa aatcagcaag taatgttgcc tatgtatact aataatacaa
    97681 agtcgttatc gttagatttg acgccacata cttacgctgt tgttaaagaa aatccaaata
    97741 atttacatat tttattgaat aattacagga cagataagac agctatgtgg gcattatcag
    97801 gaaattttga tgcatcaaaa agttggaaga aagaagaatt agagttagcg aactggataa
    97861 gcaaaaatta ttccatcaat cctgtagata atgactttag gacaacaaca cttacattaa
    97921 aagggcatac tggtcataaa cctcagataa atataagtgg cgataaaaat cattatactt
    97981 atacagaaaa ttgggatgag aatacccatg tttataccat tacggttaat cataatggaa
    98041 tggtagagat gtctataaat actgagggga caggtccagt ctctttccca acaccagata
    98101 aatttaatga tggtaatttg aatatagcat atgcaaaacc aacaacacaa agttctgtag
    98161 attacaatgg agaccctaat agagctgtgg atggtaacag aaatggtaat tttaactctg
    98221 gttcggtaac acacactagg gcagataatc cctcttggtg ggaagtcgat ttgaaaaaaa
    98281 tggataaagt tgggcttgtt aaaatttata atcgcacaga tgctgagact caacgtctat
    98341 ctaattttga tgtgattcta tatgacaata atagaaacga agttgctaag aaacatgtta
    98401 ataatttgtc gggtgaatct gttagtctag atttcaaaga aaaaggagca aggtatatta
    98461 aagttaaatt actaacgagt ggagtgcctt tgagtttagc agaagtagag gtttttagag
    98521 aatcagatgg taagcaatct gaagaggata tagataaaat aacagaagat aaagtagtct
    98581 ctacaaataa ggtagctact caaagttcaa ccaattatga gggtgtagct gctttagcag
    98641 ttgatggtaa taaagatgga gattacggac atcattcggt gactcatact aaggcagatt
    98701 ctaacgcttg gtggcaggtc gatctgggag aagagtttac ggtttctaaa gttgatattt
    98761 ataatagaac agatgccgaa cctcagcgtt tatctaattt tgatgttatt tttctatctt
    98821 catcaggaga agaagttttt agaagacatt ttgataaagt agttgatggt ttgttatctt
    98881 taaaagtacc ttctgtaggg gctaagctag tcaaaataga attaaaatca gcagctattc
    98941 cgttaagttt agcggaagtt gaagtctatg gttcaaagag aactccgaag aaactttcta
    99001 atattgcatt aaccaaagaa actcgacaga gttcaacgga ttacaatggt ttttctcgtc
    99061 tagcagttga tggaaataaa aacggagatt atggtcatca ttcagtgact cataccaaag
    99121 gagattctcc ttcatggtgg gagatagatt tagcacaaac cgaagaatta gaaaagttaa
    99181 ttatttataa tagaacagat gctgaaattc agagattatc aaattttgat attattatat
    99241 atgattcaaa taatcatgaa gtttttaaac aacatattga cagtttagaa agcaataatc
    99301 tatccataga cttaaaagga ctgaagggaa aaaaggttag aatttctttg agaaacgcag
    99361 gaattccttt aagtttagca gaggtagagg tttatactta taagtaattt taaaaattat
    99421 cacccaggct accgtaaata taatggagat ggtagtatga aagaaacaga aaaataagag
    99481 gaaaatagta tgattcaaca tccacgtatt gggattcgtc cgactattga tggtcgtcgt
    99541 caaggtgtac gcgaatcact tgaagtgcaa acaatgaaca tggctaaaag tgtggcagat
    99601 ttgatttcaa gcacattgaa atatccagat ggggaacctg tggaatgcgt gatttctcca
    99661 tctactattg gccgtgtacc agaggctgca gcttcccatg agttgtttaa aaaatcaaat
    99721 gtttgcgcaa caattacagt tacaccatgc tggtgttatg gtagtgaaac tatggatatg
    99781 tctccagata ttcctcatgc tattttggga tttaatggga cagaacgccc aggagctgtc
    99841 tatcttgcag ctgtactagc ttcacatgct caaaaaggga ttccagcctt tgggatttat
    99901 ggaagagatg ttcaggaagc tagtgacaca gatattccag aagatgtcaa agaaaaactt
    99961 ttacgctatg cgcgtgcagc tcttgcaact ggcttgatga gagacactgc ttacctatca
   100021 atgggtagtg tttcgatggg gattggtggt tctattgtaa atccggattt cttccaagaa
   100081 tacctaggaa tgcgaaatga atcggtagat atgacggagt tcacgcgccg tatggaccgt
   100141 agtatttacg accctgaaga gttcgaacgt gcgctcaaat gggtgaaaga aaacgtaaaa
   100201 gaaggattcg accataaccg tgaagacctt gttttaagcc gtgaagaaaa agatagacaa
   100261 tgggaatttg ttattaagat gttcatgatt ggacgtgact taatggttgg taacccaaga
   100321 cttgctgagc ttggttttga ggaagaagca gttggtcacc atgctttagt agctggtttc
   100381 caaggtcaac gccagtggac agatcatttc ccaaatgggg actttatgga aactttcctc
   100441 aatactcagt ttgactggaa tggtattcga aaaccatttg tatttgcgac agagaatgat
   100501 tcactaaatg gtgtgtctat gctctttaat tatctattaa caaatactcc acaaatcttt
   100561 gctgatgtgc gtacttattg gagcccagag gctgttaaac gtgtaacggg acatacttta
   100621 gagggtcgtg ctgcagctgg cttcttacat ctaatcaact ctggttcttg tacattggat
   100681 ggtacaggtc aagctactcg agatggcaaa cctgttatga aaccattctg ggagttggaa
   100741 gaaagtgaag tgcaggctat gcttgaaaat acagacttcc caccagcaaa ccgcgaatac
   100801 ttccgtggag gaggattctc aactcgtttc ttgacgaagg gggatatgcc agtaacaatg
   100861 gtacgtctca atcttctaaa aggggttggt ccagtgctac aaattgcaga aggttataca
   100921 cttgaacttc ctgaagatgt tcaccatact ttagataatc gtacagatcc aggatggcca
   100981 actacttggt ttgctccacg tttgacagga aaaggtgctt tcaagtctgt ctatgacgtc
   101041 atgaataatt ggggagctaa tcacggagcc ataacatatg gacacattgg agcagacttg
   101101 attaccttgg cttctatgtt gagaattcct gtcaatatgc ataatgtacc tgaggaagat
   101161 atctttagac ctaaaaattg gtccttattt ggaacagaag atctagaatc agcagactat
   101221 cgtgcatgtc agttgttggg accactacat aaataaaact tgtttatata ggaggtgaac
   101281 ttacgtccct cctatccttt taaaaagatt tgttaaacaa ttcacaaata attgaaaacg
   101341 aatacaaaaa gtaatataat gatgttaaat agatagcgcg gaggcgcagg aggaaaatta
   101401 tatggctaca ttttatgttc cggcagtcaa ccttattggt aaaggtgttg taaatgaagt
   101461 gggtccttat atcaaggaac ttggctataa aaaggcactt ttggttacag ataagtacat
   101521 cgaaggcagt gatattttgc ctaaggtttt aaaaccactg gatacagaag gaatcgaata
   101581 tgtcatcttt agcgatgtag agccaaaccc tacttgtaaa aatgtcacag atggggtagc
   101641 tgctttgcaa gaacatggct gtgactttat catcagtctt ggcgggggtt ctccacagga
   101701 tgcagctagt tgtatttcta tcatggctat aaatggtgga aaaccacagg attatgaagg
   101761 gcttcataag tctgctaaaa aaggcttgcc agttgtggct atcaatacaa cggcaggaac
   101821 ttctgcagaa atcactatta actatgtgat tactgatgaa gaacgcaagg ttaagatggt
   101881 aatggttgac aagaatagcc ttgctcttat ctctgttaat gacccggaac tcatgctttc
   101941 caaacctaaa ggcctgactg ctgctactgg tatggatgct ctgactcacg ctgttgaagc
   102001 tttggtaaca cctggtgctt atgatgtaac caagaaactg tctattggtg ctattgagct
   102061 tatcaaggaa tatcttcctc gtgctgtaga aaatggatac gatattgaag cgcgtgaagg
   102121 tatggtcaat gccatcttcc ttggtggtat gagctttaat aatgctggtc ttggttatgt
   102181 tcactcaatg gctcaccaac tcggtgcagt atataatttg ccacatggtg tttgctgtgc
   102241 catgttgcta ccagttatag aacgtgaaaa tgctaaacgt gtaccagaag ctttccgcaa
   102301 tgttgccaaa gccttgggcc ttcatgtgga aggtaaatca gatcaagagt gtgccgatta
   102361 tgcgattgct gagattgaga agctttctga gacagtaggt attcctaaga aattgactga
   102421 acttggtatt gaagaaaaag atttcgactt tgaatacctt tctaagaatg ccttgattga
   102481 tgcctgcgca ccaggaaatc catttatgcc aaccttagaa gaaacgattg ccttttataa
   102541 agagttattt tagcaagaga ttagacgaca ataggacaat tcacctctaa ttattgacat
   102601 ttcaggaaaa atcgcagtaa aaacggcaca gccttcttta aatgtgctat aatactagaa
   102661 aaatacttgt ggaggttcca ttatggcaat atttttcatg atttttctga ttgtttgtgt
   102721 gctcctattg gtgatagtca cactgagtac agtttatgtg gttcgtcagc agtcggtggc
   102781 gattattgaa cgctttggga aataccaaaa ggttgctaat agcggtattc atattcgctt
   102841 gccttttggg attgactcga ttgcagcacg gattcagttg cgcttgttgc aaagtgatat
   102901 tgtggttgag actaagacca aggacaatgt gttcgttatg atgaatgtag cgactcagta
   102961 ccgtgtcaac gagcagagcg tgacagatgc ttactataaa ctcatacgtc cagaatctca
   103021 gattaaatct tatatcgaag atgctcttcg ctcttctgtt ccaaaattaa ccttggatga
   103081 attgtttgag aaaaaagatg agattgccct tgaggttcaa caccaagtag cagaagaaat
   103141 gaccacttac ggctacatta tcgtgaaaac cttgattacc aaggtcgaac cagatgcaga
   103201 agttaagcaa tccatgaatg aaatcaatgc ggcgcaacgt aagcgggtcg cagcacaaga
   103261 attggcggaa gctgacaaga ttaaaattgt cactgcagct gaagccgaag cagaaaaaga
   103321 ccgccttcat ggtgtgggga ttgcccaaca acgtaaggcg attgtggatg gattggcaga
   103381 gtctatcacc gaactcaagg aagccaatgt tggcatgaca gaagaacaaa tcatgtctat
   103441 cctcttgacc aaccagtatt tggatacctt gaataccttt gcctctaaag gaaatcaaac
   103501 catcttttta ccaaatactc caaatggtgt ggatgatatc cgtacacaaa tcttgtcagc
   103561 ccttcgcgct gagaagaaat aatagactaa tactcttcga aaatctcttc aaactacgtc
   103621 agcgtcgtct tgccgtatag atgttactga cttcgtcagt tctatctgca acctcaaaac
   103681 agtgttttga gctgacttcg tcagtcttat ctactacctc aaaacggtgt tttgagcaac
   103741 ctgtagctag tttcctagtt tgctctttga ttttcattga gtataaagag cttggcaaca
   103801 ggctcttttt gtattgcgtt tattaagaaa aacaaaaaac atcgatatac atttaactaa
   103861 aaattattgt atgttatctc ccttaattag gaatgataag ggaataacta gaaagatttg
   103921 tgaatacaaa ctatttctga tatacaaaat atacagtaat aatgaatgat gggagatggg
   103981 atgaaagaat ttcaatttga gagaaagcag cgtttttctt tgaggaaata tgcaatagga
   104041 gcttgttcgg tcttgctagg aacgagttta tttttttgct ggtatgggtg ctcagcctgt
   104101 acaggataca gaaacgagtt cagcactaat ttcaagtcat tatttggatg agcaggattt
   104161 atctgaaaag ctgaaatctg agttgcaatg gtttgaatta gaaaacaagc ttttgaactt
   104221 atgggagcat taggttacta tgaaggattt gttccttatg tttcaaatca atacaaaaac
   104281 caagctgaag aagaaggcaa accgctatct gataaatata ttttcgaaaa aatcttagga
   104341 aaaacatatg cagccttcaa aaaagatcaa attaatgagc gtgtcgagaa attaggtaag
   104401 ttaaaaccta ttacaataaa ttacaacgga aaatcagaag taattgatag taaagaaaaa
   104461 ttacaagagc ttatgaataa agccgttaaa gacgaagtgg ctcaaatata gtaaaatgaa
   104521 ataagaacag gacaaatcaa tcaggacagt caaattgatt tctaaaaatg ttttagaagt
   104581 agaggtgtac tattctagtt tcaacatact ataaaatcag gcaatacaac ggctaaaaag
   104641 tttgagttta tcgaaatacc agtgcaaaaa ctgaaaaaag caatttataa agctcatctc
   104701 aaagattcag atgactttag accagaaaca tccacaccaa atctttttga aagctgtttg
   104761 aagctttgtc cttgctttct tagttcatag atctgaactt tatcttcata actcaatttc
   104821 ataataaaac accccaaaag ttagatttat tctgtctaac ttttggggtg cagttcatta
   104881 atcggtcgat tttttttgta gaaacagttg cctgattaag ttgcaagtcg atagacggct
   104941 tcggcataaa tatccatagc acggtacaaa tcttctagaa cggcacattc atttgcctga
   105001 tgttctgtct gcttcgctcc tgggaataag gcgccgaagg ctacacaatt tggcatggtg
   105061 cgagcaaaag tggcaccacc ggatgaaata gcaggactgt tatcgccagt cttttcttgg
   105121 tagatttgca tcagtgtgct aacgagttta ctgtcttttg cgacgtatag aggcgctaga
   105181 tagtcaaact cttcgtagcg gagttggtag ttttgtgcac atcttgtaag caactctact
   105241 agttcttcct tgtcagctaa gacaggagtc cgaatgtcaa tacggatttc agaacgttca
   105301 tgattgatca tgagacctgc gacattaaag gataggtgac cagaaggttc atctgctata
   105361 tcaccaaaga tttgtcttcc tgtgccgtct tgacctgctt gtgttgcaag aaaactgaga
   105421 gcagggtgtt cttggagagg agcaagaatg gtagctagtc ggatgacagc attgatacct
   105481 tgactagcat ccttagcatg ctttggcact ccgagaaccg ttacggtttg ttcagtggtt
   105541 tggtaatcat aaccagcttc tttgagaccg ttacaaacct gttcatagag gagaccttgg
   105601 tagttggcct tgtctggtac aacgttaaag gcgcctccta cttcaagctc tagttgatcc
   105661 gatcccgggc catgaagttt gacctgtaga agcccttttt cagcataggt cagaggaaaa
   105721 gatgagtcag gtgcaaagcc catactggcc tgttcttcga tggtattgta gcgtgccatg
   105781 cagcgccaga gggtttcctc atcggtacca aagataaagc gtacgcgctt tttgaactga
   105841 ataccttggt ccagcaagct ttttactgca tagagagctg cgagcgaagg gcctttatca
   105901 tcttggacac cacgtccgaa tacccagccg tctttgatag ttgcttcaaa tggcggtgtc
   105961 tgccaatctg cttcatcacc tgatggaaca acatccaaat gacagagaat ggccagaagc
   106021 tctgctccct gaccgatttc tgcatatccg taataacctt tagggtcaag ataggtagtg
   106081 aaacctatgt ctcgacaaat ctctaaagtt ttttctagga catcttggat tgcttgtcca
   106141 aaaggtgttc cattttctcc ttcattgagt actgaaggat aggaaatcaa ggtttttaat
   106201 gatataagaa attcatcttt aacttgattt gttatatcta ttttcatgga atcacctcac
   106261 tcactatttt ataggaatgg aaggaaggtt ccaaggagaa gaagggcgat ggtcactaca
   106321 ataatagcga ctacgagttt gcccatgaat ttccaccaag taccaatgtt gatacgtcca
   106381 agtgcaagag ctcccatcac aataccagat gttggtgcaa tcaagttcaa gacacctgaa
   106441 gcagattggt aagcagtgat aatcaagcta ggacggacat ttacaaattc tccaagtgga
   106501 gccatgatac ccatagttgc gctggcaaga ccagatgaag atgggatcaa gaatgacata
   106561 ggtagataga agatataagt tacaacgata aagacttgtg aagatagacc gctcaagcct
   106621 tctttacccc agttgaggat tgtatcggta atcataccgt cgttcatgat aacttgaata
   106681 ccacgagcaa tcgctacgat caaggcaaca ctgagcaagt cagcagcacc attcatgaag
   106741 gaagagataa tcttatcttc tttaagacca taaataacac caatcaggat acccataaag
   106801 gcaaagagca tggcgccttc tgggaagtac caagtaccta gtgcagaagt agatgaaccg
   106861 acaatattac caataactgg aagaccagtc aaccaagcat taaagtcatc aaaaatggta
   106921 acgccaaggt ctgtccatgg aatgaagctc aataccatca agatgaatgt caacacaaat
   106981 aagaagagaa ctgatttttg tttgctgcta agtgtagatt ctacagatga agattcttct
   107041 acgttaaagt gtttcaaatc ttctttgcga gtactataaa ccagtgactt agtcggatct
   107101 ttttgaatct tatccgcata acggtaaaca aaccaagtac taagagcagt caaggtaacc
   107161 cagaaaatca gacgaagtac gataccgtcc cctgtaccaa ctcccgcagt cgctgaagca
   107221 atacctgtcg caaatggatt cagagtagat gccaaacagc cgatttgaga accgagcaaa
   107281 ataattgcaa caccagtcag gctatcaaaa ccaacggcca tcataactgg cacaaggagt
   107341 ggatagaagg ccattgtttc ttcccccata ccataagttg taccaccgag ggcaaacaaa
   107401 ggcatcagta ccaaaattaa cattttttcg cggcccttat acttcttcac gatagaggca
   107461 atccctacgt caagagcacc agttttgttg acaatgccaa ggaaaccacc aaccataagg
   107521 atgaagaagg ctacatcaat cgctgcgctc gtttctttaa tgagcgaacc ttcctctgga
   107581 tgagtaccta gcatagcccg aatcggtgcc atgaggacat cccaaatccc ttgtggattt
   107641 tgaggctgag cctcgtaaat accttctata aaggcccccg cagggataaa ccaagttagc
   107701 actgccataa tagcaatgat tatcaataat acggtgtaag atgaaggcat cttaaaccct
   107761 tttttagctt tttcactcat ttgtttttcc tcctgatgtc taacaaagtg taaaaaacca
   107821 actactttct taaataaaca tttaagaaaa cgctttctat ttatatttgt tttaccatat
   107881 taaagtctaa aaaactaata tcttttgaaa tattgtacat gttttcaaga ataatttcta
   107941 atttgatata aagatactag aaatagaata catcttatta gtaaaacaac ttatcctttt
   108001 tcaataattg ttccgctttc agattcaatc aaggcgccta gattttcaag ggaagtaata
   108061 actgcttttc cttctggacg accattgaca aaagcgatag ctgcttctac ttttggaagc
   108121 atgctacctg gtgcaaactg atcttgtttg atatattctt ccagctgggc aacattcaca
   108181 tgttccaatt tttcctggtt tggcttgttg tagttaacaa atacataatc tacacctgtc
   108241 aaaacgatga agaggtctgc atcaaccaat tctgccaaac gttgggaagc gaagtcttta
   108301 tcaataaccg cttcgacacc agtcaaatgt ccattgtttt ctttgacgac gggaataccg
   108361 ccaccacctg cagctacgac gacttgacca ttatttaaaa gagtacggat ggtttcaatt
   108421 tctttgatgt caacaggttt tggtgaggca acgaccttac gccagccacg gccagcatct
   108481 tccttgaaag tcgctccgct tttttcggct tctgcttttg cttcttcttc tgaatagaaa
   108541 ggaccgattg gtttactcaa gttaacaaaa gctggatcat ttttatctac gacaacttgc
   108601 gttacaacag aggcaacatt tttttcgatg ccttcatcca agagagcatt ttgcaaagca
   108661 tttttcaacc agaaaccgat gctaccttct gtcatagcga caagtgagtc gagtgggaag
   108721 gcagggttct tttcagagtc tgatgccaaa tgttggagca agagattccc aacttgaggt
   108781 ccattaccgt gagtgataat caaatcatct ccatttttaa tcaattttac aagatgctta
   108841 gctgtttcaa ctaaagcttc ttgttgagcc tttgctgatg ggtcagaaga aagaatcgca
   108901 tttcctccca aagctactac aattttacga tttgccataa attctccttt atcacactca
   108961 atagaatgcg tttagatttc aatttaatga tttttcacat attttataag aaataataga
   109021 ttaccattac ataaaagagg accggactaa agctattagt cgcagccctc atagctgttg
   109081 gtagacggtt tattatctaa aattatactt taggaatata aaggttacca agtgtagcag
   109141 ccataacagc tttgatagtg tgcatacggt tttctgcttg atcgaagtgg cgagcgtact
   109201 tgctgcggaa gacttcgtct gttacttcca tttcttctac accaaatttt tcagcaacgt
   109261 ctttaccata aacagtgtga gtatcgtgga atgctggcaa gcagtgtagg aagatcaagt
   109321 tttcattgcc tgctttttta actaagtcca tattgacttg gtaaggttta agaagagcta
   109381 cacgttctgc gaatttgtct tcttcaccca ttgataccca aacgtctgtg taaagaacgt
   109441 ctgcatcttt aactgcttca tcagcatctt cagtgatgag aacatgtgcg ccactttctt
   109501 tagcaaatcc ttctgctaat tcaacgattt ctttttctgg gaagagttct tttggtgaga
   109561 agatgtgaac attgacacca aggatagcac ctgttacgag caagctgttg gcaacgttgt
   109621 tacgtccatc accacagtat accaatgtca agccttccaa gcgaccgaag ttttcttgaa
   109681 cagtcaagta gtcagcgagc atttgagttg ggtgccattc gtcagttaga ccgttccata
   109741 ctggaacgcc tgagaattct gccaattctt caaccatacg ttggctgaat ccgcggaatt
   109801 caatcccgtc aaacatacgt cccaatactt tagcagtatc ttcagtagat tcttttttac
   109861 ccaactgaat atcatttgct ccgaggtatt ctgggtgagc accaaggtcg atagccgcag
   109921 ttgtaaaggc tgcacgagta cgagtagatg ttttttcaaa taggagagcg atattcttgc
   109981 cagcaaggta gtggtgttga atattgcgtt ttttcaaatc tttcaagtga gctgaaagac
   110041 caataaggta ttctaactct gcacgggtaa agtctttttc tgctaagaag ctgcgtcctt
   110101 ggaatactga atttatcatt ttattatttc ctctttctat tttttacatt ttctattgac
   110161 gaatgccgaa cagctattac acttcttcac gttcaaatgg catggacata caacgaggtc
   110221 caccacggcc ccgaaccaat tcacttccgc gaatcttaat caagcgaagc ccgtattctt
   110281 ccaaaatctt attggtcacg gtattgcggt cataaacaac taccacacca ggtgcgatgg
   110341 tcaaagtgtt agaaccgtcg ttccattgtt cacgcgcagc tgctacgata ttgccaccac
   110401 cgcaacgaat caaatgaact ttttctacac caaggttttg agcaagaagt tcagctaagt
   110461 cacctttctc ttcaacgatt ttaagttttt cgttttcgta agtaactgag taaacgtgaa
   110521 ggtcgccttc gatttctggg tgaatagtga acttgtcata gtctaccata gtgaagacag
   110581 tatccaagtg catgaattta cggttgttag caaattcaaa ggccaaaacc ttcttgaagc
   110641 caacattttt cttgaagatg ttgaccaaaa gtttttcgat agaagctgcg tctgtacgtt
   110701 gagagatacc tactgcaagg acgtctttag aaagaactag ctcgtctcca ccttcgatac
   110761 gcgtatcttc ttcacggttg tagaccaaat ccacttttcc gccatagatt gggtggtatt
   110821 tgaagatata cttaccgtag agtgtttcac ggttacgagt atctgcaaac atgtggttaa
   110881 gcgatacggc gtttccaatt gttgcaaatg ggtcgcgagt gaaatagagg tttggcatcg
   110941 ggtcaattgc aaatggatac tctgattcaa ctaagtcagt tagatcttta gcttcgtcag
   111001 gaatttctgg caattcaact ttttgaatcc cagccattgt tttttcaacc aattcttggt
   111061 tgtccttgat gccgtgaagc aattcacgaa tagcaacctt ggtttgacga tcacggatgt
   111121 tggcttcgtc taagtattcc tcgataaatt gatcgcggat ttctggagag gtcaatgatt
   111181 cagcagcgag ttgttctagg tagagaacct caattccttc atcgcgaaga gcttgggcaa
   111241 atgcatcatg ttctttttga gcatcttcca agaaaggaat atcatcaaaa agaagccttt
   111301 caagatagtc cggcaacaag ttttctaact ccttgcctgg acggtgcaac ataacttttt
   111361 tcagtttccc aatttctgag aagacctgaa ttggatgtga agacatgtat tttcctcctt
   111421 aaaaattttg acttggcacc attttgggta ccgcttacat gtatgttata acgcaattcc
   111481 taggtaatgt caatggctat aatttctcgg aaaataatat aaattatgat gtttagcaca
   111541 attttatgtt attatacata acataggata gaatacatag atacaaatgc ataaacttct
   111601 ataaaaagga tataaaattt ttttaaaaaa tttttcaaaa aatatacaaa tgaccaaaaa
   111661 gtgtccaatt atcatctggt tatcacttgg atctgtataa agagaaatgt ttgtgtgaaa
   111721 ggataaaaag atgcaacatt cttttgaaga tagattttgg agaagcattt cttgttcaat
   111781 tgtacaaatt atagaatctt ttctgagtat ttaggaagag ataattatct tattgaccct
   111841 ctttttattt tttgttatag tcgacgaggt gatagtttag aataatcact tattcacaat
   111901 ctgtggaaaa gtctggagag tgaatggtct tcacacaatg acctgaaaga agcctgagaa
   111961 taattatgga gagtagtatt ctgagaggtg ttagcagaac catatgacag agctgtttga
   112021 agagggaaca ttgaggagaa aaatcctgag cctaccagtt ggagttggaa agagctggct
   112081 gttagatcat ggtttattat ccacaacctg tggataacct tgtgaacaag agaagttgca
   112141 aaagaaggag atatataacg atgaagaaaa tcaaaccgca tggaccgtta ccaagccaga
   112201 ctcagctagc ttatctggga gatgaactag cagcttttat ccacttcggt cctaatacct
   112261 tttatgacca agaatggggg actggacagg aggatcctga gcgctttaac ccgagtcagt
   112321 tggatgcgcg tgagtgggtt cgtgtgctca aggaaacggg cttcaaaaag ttgattttgg
   112381 tggtcaagca ccacgatggc tttgtccttt atccgacagc tcacacagat tattcggtta
   112441 aggtcagtcc ttggaggaga ggagagggcg acttgctcct tgaagtatcc caagctgcca
   112501 cagaatttga tatggatatg ggggtctacc tgtcaccgtg ggatgcccat agtcccctct
   112561 atcatgtgga ccgagaagcg gactacaatg cctattatct ggctcagctg aaggaaatct
   112621 tatcaaatcc tgcctatgga aatggaggga aatttgctga ggtttggatg gatggtgcca
   112681 gaggagaggg cgcgcaaaag gttaattatg aatttgaaaa atggtttgaa accattcgtg
   112741 acctgcaggg cgattgcttg attttttcaa cagaaggcac cagtatccgc tggattggca
   112801 atgaacgagg gtatgcaggt gatccactgt ggcaaaaggt gaatcctgat aagctaggaa
   112861 cagaagcaga gctggactat cttcagcacg gggatccctc gggcacgatt ttttcaatcg
   112921 gagaggcaga tgtttccatc cgtccaggct ggttctacca tgaggatcag gatcctaagt
   112981 ctctcgagga gttggtcgaa atctactttc actcagtagg gcgaggaact ccactcttgc
   113041 ttaatattcc gccgaatcaa gctgggctct ttgatgcaaa ggatattgaa cgactttatg
   113101 aatttgcgac ctatcgcaat gagctctata aagaagattt ggctctggga gttgaggtat
   113161 ctggttcagc tctttccgca gactttgctt gtcgccattt gacagacggc cttgagacca
   113221 gctcttgggc aagcgatgca gacttgccca tccagttaga actcgactta ggttctccta
   113281 aaacttttga tgtaattgag ttaagagaag atttgaagct agggcaacga atcgctgctt
   113341 ttcatgtgca agtagaggtg gatggtgtct ggcaggaatt tggcaggggc ttcacagttg
   113401 gtcataagcg cctcttgcga ggtccgctag tagaggcaca gaaggtgcgc gtgatgatta
   113461 ccgaggcaca atctattcct gtattgacca agatttccct ttataaaact ccgaggctat
   113521 cacaaacagt agctgttcag gggctagcat ttgcagaaaa aagcctagct gtggcaaagg
   113581 gagaaaatgc ctattttaca gttaagcgca gagaatgtag tggtccttta gaagctaaga
   113641 tttcgattca accggggaca ggtgtccatg gtgtcgccta tcaggatgag attcaagtcc
   113701 ttgcgtttca agctggtgag actgaaaaaa gtctgacgct accaaccttg tatttcgcag
   113761 gagataaaac cttggatttc tatctgaacc taacggtgga tggtcagctt gtggatcaac
   113821 ttcaagtcca agtttcataa aagaagaacc tttgcgcgat gcaaaggttc ttttggttat
   113881 tagtgatttg gtagccagct gagggtgaaa attagttgtt cagcttttaa gaggtcttgg
   113941 tgttgaatag ttgatacgag tgttttgttc agtcggcatt ctttgacaaa gttaaaatgg
   114001 ttgtggtttt gtttagtatg gatatccagc catttatctt ctttagctag gtagactcgt
   114061 agatggtcaa agagagggat tccgaggtca tagcttggtt ttcctggaca ggttggataa
   114121 aatccgagag ctgaccagat gtaccaagca gagagactac cattgtcttc atctccagga
   114181 taggcttccc aacttgggtg aaaagctttc tgacggagcg tcttgataag aagggcagtg
   114241 tagtcagggt aatcgctgta gcggaagaga taaggaatgt ggaaactagg ctggttggaa
   114301 atggctattt gtccaaaagg agcagtagcc atctcgctca tttcgtgaat ttcgtaacca
   114361 tagcctgttg tttcaaagag gggagcatct tgacaggctt tcaaaagata gttgctaaag
   114421 gtttcttttc cacccatcag ttggattaag ccagggatgt cgtggagaac gcctaaagta
   114481 gcttgaatgg cagagcattc agcgtagtct cgcccccaac tataaggaga gaagtcaggg
   114541 tgaaagtttc cttgattgtc tcgtgctcgc atgtaacctg tctcagcgtc aaatagctgg
   114601 cggtaatttt gtgaagcagc cttgtaggtt tcagcgattt ctatgttctc tagttttttg
   114661 gcacagctgg cgatacaaaa gtcactatag gcatagtcta gagtatggct aacactttca
   114721 tggtggtcgg tagagaggta acctagttct tggtattggg ctagtccgtg gcggccattg
   114781 attccgagag ggtcggcttt gctggctgtt tcgagcatgg cttggaagag ttctccttct
   114841 aggtcggggg ccatgtcctt gcaggtgcta tctgcgataa taccgtctaa aagtgtacct
   114901 ggcatcatac cccgttcatc tggagccagc cattttggaa ggaaaccagt atcgcggtag
   114961 ctattgagga aaccttctaa aaagcgttga tagtgctccg gtatgataag ggcaaagagg
   115021 gggaaggtgg tgcggaaggt atcccagaaa ccattgttgc taaagaggac accaggcttg
   115081 acagtaccag tagccagatc catgtggatg gcttgccctg attcattaat ctcataaaaa
   115141 gtctgtggga agaggaagag tctgtagagg cagtggtcaa agaaggttcg gtcagcctct
   115201 cctgtctcta taatgtcaaa acgatggagg agattttccc aatccacttg ggcacttgat
   115261 ttacagctat caaaatcttc ttgaggtaga ttgattagag cttgagaagg agagatgaaa
   115321 gaagtggcta gttgcatctc ggtttgacta cttgctaagt caattcgcca gtccccagct
   115381 tcttggctga tagcaagaat atccgtgttc atttgcaggg cagtgaacat cgttagcgaa
   115441 tttttgttag tttcagtttt accttcttgt cgcagggcaa gagtccgctt atctacttgc
   115501 tctacggtca gttcatctgc tgcgtgaaga tagagggaga gggctttgcc ttgcttttgc
   115561 ttcaaacgaa tagaagcacc atagcaagtc ggtgtgagct gggtttcaat ctgataacgc
   115621 agagaaaaga gcttcaaata gtgaggttgg aagcaagctt tatctatatc ataagaagac
   115681 tggcggtgaa agaggctgtc tccacccagt tgactggtga caggtgtcag aaggagccaa
   115741 gagtagtccc caatccaagg actgggctgg tgagttaatc gaatcccctg aaagataggc
   115801 agatgcggat caaaaaacca agatccatcc tggtcactgg tctggggcac aaagtaattc
   115861 atcccaaaag gcacgcctgt gtatggcagg gtatttcccc gagaaaaggc atgcttgttg
   115921 gtagttccaa agcgggtatc gatggtttca agtagtggtt tcatagtctt tcctttagct
   115981 gtttttctac attatatcag aaaaagaggg cctttagaaa aggagtttca aaaataacta
   116041 ttttgtagaa aaatgactat catttgtgta tgtattttct gtctcaaaag ctatatactg
   116101 aacatgaaac ttgtttgaaa gagggaattg cacgatgatt tattcgaaag aaattgttag
   116161 agaatggcta gatgaagtag cagagcgggc taaggaccat ccagagtggg tggatgtttt
   116221 cgagcgttgc tacaccgata ccttggacaa tacggttgaa atcttagaag atggttcaac
   116281 ttttgtcttg actggggata ttcctgccat gtggcttcga gattcgacag cccaactcag
   116341 accctacctt catgtagcta aaagagatgc cctcctgcgt cagaccattg caggtttggt
   116401 caaacgtcag atgaccttgg tactcaagga tccctatgct aactccttca acattgagaa
   116461 gaactggaaa gggcaccacg agactgacca cacagacctt aacggctgga tctgggagcg
   116521 caagtatgag gtggattcac tttgctatcc tttgcagttg gcttatctcc tctggaaaga
   116581 gactggcgag actggtcagt ttgatgagac ttttgtcgca gcgactaagg aaattctcca
   116641 tctatggaca gttgaacaag accacaagaa ctctccttat cgttttgtcc gagatacgga
   116701 ccgtaaggaa gacaccttgg taaatgatgg ctttggacct gactttgcag tgacaggtat
   116761 gacttggtca gcttttcgtc cgagtgacga ttgctgtcag tatagttact tgattccgtc
   116821 taatatgttt gccgtagtag tcttgggtta tgtgcaagaa atctttgtcg aattagacct
   116881 agctgatagc cagagtgtta ttgctgatgc caagcgtctt caggatgaaa tccaagaagg
   116941 aatcgaaaac tacgcttaca ccaccaacag caagggcgaa aagatttacg cttttgaagt
   117001 agatggccta ggaaatgcca gcatcatgga tgatccaaat gtaccaagtc tactagctgc
   117061 gccctatctg ggctactgtt cgatcgatga tgaagtgtat caagccactc gccgtaccat
   117121 tctgagctct gaaaatccat acttctacca aggagaatac gctagcggtc tcggaagttc
   117181 tcataccttc tatcgctata tctggccact cgccctttct atccaaggat tgacaacaag
   117241 agataaggca gagaaaaaat tcttgctgga tcagctggtt gcctgcgatg gtggtacagg
   117301 tgtcatgcac gaaagcttcc acgtagatga tccgaccctc tactctcgtg aatggttctc
   117361 ctgggctaac atgatgttct gtgagttggt cttggattac ttggatattc gctaaggggc
   117421 tcgctttagc tcaaccgatt cttatcagaa tcacaagttt acatttaaaa cgttaaaatt
   117481 taaatttaga atgaggtttt acttcatgga aaatgttgtt gtacatatta tctcacatag
   117541 tcactgggac cgtgagtggt acttgccttt tgaaagccat cgtatgcagt tggtggaatt
   117601 gtttgacaat ctctttgatc tctttgaaaa tgaccctgag ttcaagagtt tccacttgga
   117661 tggacaaact attgtccttg acgactactt acaaattcgc cctgaaaatc gtgacaaggt
   117721 ccaacgctac attgacgagg gcaaacttaa aattggtccc ttttacatct tgcaggatga
   117781 ctacttgatc tccagtgaag ccaatgtccg aaataccttg attggtcaag cagaatgtgc
   117841 aaaatggggc aaatctactc agattggtta tttcccagat acctttggaa atatgggaca
   117901 agcgcctcaa attcttcaac aatcaggcat tcacgtggca gcctttggtc gtggtgtgaa
   117961 gccgattgga tttgacaacc aagtcctcga agatgagcag tttacttccc agttttcaga
   118021 aatgtactgg cagggtgcgg atggtagtcg tgttttaggt attctctttg ccaactggta
   118081 cagtaatggg aatgaaatcc cagttgacaa agatgaggcc ttgaccttct ggaaacaaaa
   118141 attgtcagat gtgcgtgcct acgcttcgac caaccaatgg ttgatgatga acggctgtga
   118201 ccaccagcct gtacagaaaa atctgagcga agccattcgt gtggcaaatg aactcttccc
   118261 ggatgtaatc tttgttcata gttcttttga tgaatatgtt caagctgtag aaggtgcgct
   118321 tcctgaacac ttatcaactg ttacaggcga gttgaccagt caggaaacag atggctggta
   118381 cacacttgcc aacacttctt catcccgcat ttacctaaaa caagccttcc aagaaaatag
   118441 caacctccta gagcaagtgg tagaaccctt gactattatc actggtggac acaaccacaa
   118501 ggaccagttg acctatgctt ggaaaacact tttgcagaat gcgccacatg atagtatctg
   118561 tggctgtagc gtggacgaag ttcaccgcga gatggaaacg cgttttgcca aggtcaacca
   118621 agtaggaaac tttgttaaaa gtaatttgct caacgagtgg aagggtaaaa ttgctacgga
   118681 taaggctcaa agtgactatc tctttactgt cattaacaca ggcttgcatg ataaggtcga
   118741 tactgtctgc acagtgattg atgtggcgac ttgtgatttc aaggaattgc acccaacaga
   118801 aggctacaaa aagatggctg ctcttatctt gccaagttac cgtgtggagg acttggatgg
   118861 tcgtcctgta gaggctacaa tcgaagacct cggagctaat tttgaatacg atttaccaaa
   118921 agataagttc cgccaagctc gtattgctcg acaagtgcgc gtgaccattc cagttcacct
   118981 agcaccgctt tcttggacaa ccttccaatt gctggaagga gaacaagaac accgtgaggg
   119041 tatttaccaa aacggagtga ttgatacacc attcgtaacg gtgagtgtgg atgacaacat
   119101 cacagtctat gacaagacaa ctcacgaagc ctatgaagac tttatccgct ttgaagaccg
   119161 tggggacatt ggaaacgagt atatctattt ccaaccaaaa ggaacagagc caatctttgc
   119221 agagcttaag ggccacgagg tcttggaaaa cacagcttgc tatgctaaaa tcttgctcaa
   119281 acatgaattg accgtgcctg tcagtgcgga tgaaaagcta gaagaagagc aacaaggtat
   119341 catcgagttt atgaagcgtg aggctggacg gtcagaagaa ttgacaaaca ttcctctgga
   119401 aactgagttg actgtcttcg ttgacaatcc acaaatccgc ttcaagactc gctttactaa
   119461 cactgccaag gatcaccgta tccgtatctt ggtcaagact cataacacgc gtccaagcaa
   119521 tgattctgaa agtatctatg aggtggtgac acgaccaaac aaaccagctg cttcatggga
   119581 aaaccctgaa aatcctcaac accaacaagc ttttgtcagt ctgtatgacg atgaaaaagg
   119641 ggtgactgta tccaataagg gattgaatga atacgaaatc cttggggata acaccattgc
   119701 cgtgaccatt ttgcgtgcat caggtgagct aggtgactgg ggctacttcc caacgccaga
   119761 agcacaatgc ttgcgtgagt ttgaagtcga gtttgcactt gaatgccacc aagcccaaga
   119821 acgcttctca gcctatcgtc gtgccaaagc cttgcagaca ccgtttacca gccttcagct
   119881 tgctagacag gaaggaagcg tggttgcgac tggtagcctc ttgagccatt ctgttctcag
   119941 cataccgcaa gtttgtccaa cagcctttaa agtggcggaa aatgaagaag gctatgtcct
   120001 ccgttactat aatatgagtc aagaaaatgt gcgcatatca gaacatcaac aaaccattct
   120061 tgacttactt gagcgaccat atccagttca ttcaggacta ttggctccac aagagattcg
   120121 tacagaattc atcaaaaaag aagaaattta atttcaaaaa gtaaacatca aaagaaagga
   120181 ggggcgaaaa ggtaagaact aactgctgat tcgctccttt ttatggtaaa aacaatgacc
   120241 attgcaacga ttgatatcgg agggactggg attaagtttg ccagtctgac tcctgatggg
   120301 aaaatactgg ataagacaag tatttcaacg cctgaaaact tggaggattt actagcgtgg
   120361 ctagatcaac gcttgtcaga acaggattac agtgggattg ctatgagcgt tccaggtgcg
   120421 gtcaatcaag agacaggtgt gattgatggc ttcagtgcgg tgccctacat ccattgcttt
   120481 tcttggtatg aggcgcttag ctcttatcag ctacctgtcc atttagaaaa tgatgccaac
   120541 tgcgttggac tcagtgaact actagctcat ccagagcttg aaaatgcagc ctgtgtcgtg
   120601 attgggacag ggattggcgg agccatgatt atcaatggta gacttcatcg aggtcgccac
   120661 ggtctgggtg gagaatttgg ttacatgaca acccttgccc ctgctggaaa acttaataac
   120721 tggtcgcaac tagcatcaac tgggaatatg gtacgatacg taattgaaaa atctggtcat
   120781 actgattggg acggtcgcaa gatttaccaa gaggccgcag ctggtaatgc tctttgtcaa
   120841 gaagccattg agcgcatgaa ctgcaatctg gcgcaaggct tgctcaatat ccagtatctg
   120901 atcgatccag atgtcatcag tctgggtggc tctatcagtc aaaatccaga ttttatccaa
   120961 ggtgttaaga aggctgttga agactttgta gatgcctacg aagaatacac ggtcgcacca
   121021 gttatccagg cctgcaccta tcacgcagat gcaaatctct acggtgccct tgtcaactgg
   121081 ctacaggagg aaaagcaatg gtaagattta caggacttag tcccaaacaa acgcaagcta
   121141 ttgaggtttt aaaaggtcac atttctctac cagatgtgga agtggctgtc actcagtctg
   121201 accaagcctc tatctctatc cagggtgagg aaggtcacta tcaattgacc taccgcaaac
   121261 ctcaccaact ttatcgtgcc ttgtccttgt tggtaacagt tctagcagaa gctgataaag
   121321 tagagattga ggaacaagca gcttacgaag atttggctta catggttgac tgttctcgaa
   121381 atgcggtgct gaatgtggct tctgccaagc agatgattga ggtcttggct ctcatgggct
   121441 actcaacctt tgagctttac atggaagaca cttaccagat tgaaggacag ccttactttg
   121501 gctatttccg tggagcttat tcagcagagg agttgcagga aatcgaagcc tatgctcaac
   121561 agtttgacat gacctttgta ccatgcatcc agaccttggc ccacttgtcg gcctttgtca
   121621 aatggggtgt caaggaagtg caggagctcc gtgatgtaga ggacattctt ctcattggcg
   121681 aagaaaaggt ttatgacctg attgatggca tgtttgccac gttgtctaaa ctgaagactc
   121741 gcaaggtcaa tatcgggatg gacgaagccc acttggttgg tttgggacgc tacctgattt
   121801 tgaacggtgt tgtggatcgt agtctcctca tgtgccaaca cttggagcgc gtgctggata
   121861 ttgctgacaa atatggtttc cactgccaga tgtggagtga tatgttcttc aaactcatgt
   121921 cagcggatgg ccagtacgac cgtgatgtgg aaattccaga ggaaactcgt gtctacctag
   121981 accgtctcaa agaccgtgtg actctggttt actgggatta ttatcaggat agcgaggaaa
   122041 aatacaaccg taatttccgc aatcatcaca agattagcca tgaccttgca tttgcagggg
   122101 gagcttggaa gtggattggc tttacacctc acaaccattt tagccgtcta gtggctatcg
   122161 aggctaataa agcctgccgt gccaatcaga ttaaagaagt catcgtaacg ggttggggag
   122221 acaatggtgg tgaaactgcc cagttctcta tcctaccaag cttgcaaatc tgggcagaac
   122281 tcagctatcg caatgaccta gatagtttgt ctgcgcactt caagaccaat actggtctaa
   122341 cggttgagga ttttatgcag attgaccttg ccaacctctt accagaccta ccaggtaatc
   122401 tcagtggcat caatcccaac cgctatgtct tttatcagga tgttctctgt ccgatacttg
   122461 accgacacat gacacctgag caggacaagc cacacttcgc tcaggcggcg ggaactattg
   122521 ctgacattaa agaaaaagct ggaaactatg cttatctctt tgaaactcag gcccagttga
   122581 atgctatttt aagtagcaaa gtagatgtgg gacgacgcat tcgtcaggcc taccaagcgg
   122641 atgataaaga aagtttacaa caaatcgcca gacaagaatt accagaactt agaagccaaa
   122701 ttgaagactt ccatgccctc tttagtcacc aatggttgaa agaaaacaag gtctttggtt
   122761 tggatacagt tgacatccgt atgggcggac tcttgcaacg catcaaacga gcagaaagcc
   122821 gtatcgaggt ttatctggct ggccagcttg accgcatcga cgagctggaa gttgaaatcc
   122881 taccatttac tgacttctac gcagacaagg atttcgcagc aactacagct aaccagtggc
   122941 ataccattgc gacagcgtcg acgatttata cgacttaata cttttcgaaa atctcttcaa
   123001 accacgtcag cttccatcta caacctcaaa acagtgtttt gagcagcctg cagctagctt
   123061 cctagtttgc tctttgattt tcattgagta taaaaacaag aacaccttgc ttggcgcagg
   123121 gtgtttcgcg tgaaacagaa gaattatctg gtttcaaatg ctacagttag acaaacttat
   123181 gataaaatag cagaaagtga atgtttccta agagcaattc tatcgatgag caattggagg
   123241 tattatgcta cacttaaaat tagtaaaaca agaaatagaa gctgaaaagc cagcatctgt
   123301 agaagcctgg gtcatttccg tcaaatttaa aaaaggttgc taccgacata tatagattcc
   123361 aaaaacaaaa acgttagcgg aactagcaga tgtgatttta tggagtttcg attttgtaaa
   123421 tgctcatgct cacgcatttt tcatggataa tgttgagtgg agtcatgcag attcttactt
   123481 tcttagcttt gttagtgacg atgttgaaga acgttacaca gaaaatgtct atctggatag
   123541 cctaagtgtc aaacaaaaat ttaagtttct tttcgacttc ggtgatgaat ggcgttttga
   123601 atgctaagtg ctgagagaaa tcgagacaga ggacgaagaa gcttatctcg tacgttcggt
   123661 tggaacgtcg ccagaacaat atccagatta tgatggtttt gactatgaag aatggtaaaa
   123721 ttgaaatcta aaaaacaatt ggaatcagtc tgtgtaggct tagtatttca atagacttcc
   123781 tgcaaaacta gaatcctagt tcatgattga taataccagc aatcaaattc attcgtaatc
   123841 cgaagcgttt acgatgattt cgatagattg ttgaaaacat tttaaacgtt tttactttgg
   123901 caaagatgtt ctcaaccttg cttctctcct tggatagcgc atggttacag gctttatctt
   123961 cagctgttag cggcttgagt ttgctggatt tacgtggagt ttgtacttga ggatatatct
   124021 tcatgagtcc ttaataacca ctgtcagcca agattttacc agcttgtccg atatttctac
   124081 gactcatttt gaacaacttc atatcatgac aatagttcac agcgatatcc aaagaaacaa
   124141 ttctcccttg acttgtgaca atcgcttgag ccttcatagc gtgaaatttc tttttaccag
   124201 aatcattcgc taattgtttt tttagggcga ttgattttta cttccgtcgc atcaatcatt
   124261 accgtgtcct cagaactgag aggagttctt gaaaccgtaa aaccactttg aacaagagtt
   124321 acttcaaccc attggctccg acggataaag ttgctttcgt gaataccaaa atcagccgca
   124381 atttgttcat aagttcgata ttctcgcact attgaagagt gggcataaga aggtcttcta
   124441 ggcttaattt aggttttcgt ccaccttttg cgtgtttaag ttgataagct gtttttaata
   124501 cagctaacat ctcttcaaaa gtggtacgct gaacaccaac aagacgctta agtcgtgtat
   124561 cagttaattg tttacttgct tcataatttc gcagggagtc tattgactct ttggtaggtg
   124621 tcaatgtttt tttcatctat cccgagaatt attttcccac catttgtatt tgcaaatgct
   124681 gagtaggttt cccagaaaga ctctggaaga ttgtttttag cttttttgta ttctaaatca
   124741 accccttcaa attttaagtc catatttttc ctttacatct gttttttgtg gttctggtat
   124801 ttgttcaagt tgagtgataa tatagcgaat tgaatttcga gagtttttac tcagttaatt
   124861 tcttttttaa cccactttaa tttctttttt aatacgggtt aaaaaagaaa ttaaagtggg
   124921 ttaatttttc ttgacttaaa atttaaaaat gatatactgt gtttatggag agatgacaat
   124981 ttataaaatg tactactcta ttctactaga taatgattga ataaaacttt ttataacaac
   125041 ggctagcaaa gttataattt tatatctatt agaaaataaa tatgtaagga aatttaaatg
   125101 aaaaaaacta caatattatc attaactaca gctgcggtta ttttagcagc atatgtccct
   125161 aatgaaccaa tcctagcaga tactcctagt tcggaagtaa tcaaagagac taaagttgga
   125221 agtgttattc aacaaaataa tatcaaatat aaggttctaa ctgtagaagg taacatagga
   125281 actgttcaag tgggtaatgg agttactcct gtagagtttg aagctggtca agatggaaaa
   125341 ccattcacga ttcctacaaa aatcacagta ggtgataaag tatttaccgt tactgaagta
   125401 gctagtcaag cttttagtta ttatccagat gaaacaggta gaattgtcta ctatcctagc
   125461 tctattacta tcccatcaag cataaaaaaa atacaaaaaa aaggcttcca tggaagtaaa
   125521 gctaaaacta ttatttttga caaaggcagt cagctggaga aaattgaaga tagagctttt
   125581 gatttttctg aattagaaga gattgaattg cctgcatctc tagaatatat tggaacaagt
   125641 gcattttctt ttagtcaaaa attgaaaaag ctaacctttt cctcaagttc aaaattagaa
   125701 ttaatatcac atgaggcttt tgctaattta tcaaatttag agaaactaac attaccaaaa
   125761 tcggttaaaa cattaggaag taatctattt agactcacta ctagcttaaa acatgttgat
   125821 gttgaagaag gaaatgaatc gtttgcctca gttgatggtg ttttgttttc aaaagataaa
   125881 actcaattaa tttattatcc aagtcaaaaa aatgacgaaa gttataaaac gcctaaggag
   125941 acaaaagaac ttgcatcata ttcgtttaat aaaaattctt acttgaaaaa actcgaattg
   126001 aatgaaggtt tagaaaaaat cggtactttt gcatttgcgg atgcgattaa acttgaagaa
   126061 attagcttac caaatagttt agaaactatt gaacgtttag ccttttacgg taatttagaa
   126121 ttaaaagaac ttatattacc agataatgtt aaaaattttg gtaaacacgt tatgaacggt
   126181 ttaccaaaat taaaaagttt aacaattggt aataatatca actcattgcc gtccttcttc
   126241 ctaagtggcg tcttagattc attaaaggaa attcatatta agaataaaag tacagagttt
   126301 tctgtgaaaa aagatacatt tgcaattcct gaaactgtta agttctatgt aacatcagaa
   126361 catataaaag atgttcttaa atcaaattta tctactagta atgatatcat tgttgaaaaa
   126421 gtagataata taaaacaaga aactgatgta gctaaaccta aaaagaattc taatcaggga
   126481 gtag
//
LOCUS       DAVLCS010000002        80995 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLCS010000002 DAVLCS010000000
VERSION     DAVLCS010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 80995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80995
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.002"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            <1..175
                     /locus_tag="VXC78_000118"
     CDS             <1..175
                     /locus_tag="VXC78_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEV0582275.1"
                     /translation="KILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAY
                     KDKVYTRGIWIRD"
     gene            571..1434
                     /locus_tag="VXC78_000119"
     CDS             571..1434
                     /locus_tag="VXC78_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0582276.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            1720..1920
                     /locus_tag="VXC78_000120"
     CDS             1720..1920
                     /locus_tag="VXC78_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV0582277.1"
                     /translation="MLNLQFAETMELTEAELEIVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            1987..2652
                     /locus_tag="VXC78_000121"
     CDS             1987..2652
                     /locus_tag="VXC78_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0582278.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            2724..3950
                     /locus_tag="VXC78_000122"
     CDS             2724..3950
                     /locus_tag="VXC78_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0582279.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICMINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTTLYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(4303..4377)
                     /locus_tag="VXC78_000123"
                     /pseudo
     CDS             complement(4303..4377)
                     /locus_tag="VXC78_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4448..5104
                     /locus_tag="VXC78_000124"
     CDS             4448..5104
                     /locus_tag="VXC78_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV0582280.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWHNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGDLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRISVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGMVLDGQ
                     "
     gene            5094..5303
                     /locus_tag="VXC78_000125"
     CDS             5094..5303
                     /locus_tag="VXC78_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV0582281.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKYKGLPTIVERFLKFL
                     PVSIIFALILSRVVTGKVGNLPQIK"
     gene            5521..6351
                     /locus_tag="VXC78_000126"
     CDS             5521..6351
                     /locus_tag="VXC78_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0582282.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            6505..7359
                     /locus_tag="VXC78_000127"
     CDS             6505..7359
                     /locus_tag="VXC78_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0582283.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            7459..8832
                     /locus_tag="VXC78_000128"
     CDS             7459..8832
                     /locus_tag="VXC78_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV0582284.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYHTHIELVE
                     ELIRSYE"
     gene            8825..9886
                     /locus_tag="VXC78_000129"
     CDS             8825..9886
                     /locus_tag="VXC78_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV0582285.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            9888..10580
                     /locus_tag="VXC78_000130"
     CDS             9888..10580
                     /locus_tag="VXC78_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0582286.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(10609..11178)
                     /locus_tag="VXC78_000131"
     CDS             complement(10609..11178)
                     /locus_tag="VXC78_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0582287.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            11313..11927
                     /locus_tag="VXC78_000132"
     CDS             11313..11927
                     /locus_tag="VXC78_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0582288.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            11929..13575
                     /locus_tag="VXC78_000133"
     CDS             11929..13575
                     /locus_tag="VXC78_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0582289.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            13587..14873
                     /locus_tag="VXC78_000134"
     CDS             13587..14873
                     /locus_tag="VXC78_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0582290.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFAIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            14925..15458
                     /locus_tag="VXC78_000135"
     CDS             14925..15458
                     /locus_tag="VXC78_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0582291.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            15536..16006
                     /gene="nrdI"
                     /locus_tag="VXC78_000136"
     CDS             15536..16006
                     /gene="nrdI"
                     /locus_tag="VXC78_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV0582292.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(16299..17561)
                     /locus_tag="VXC78_000137"
     CDS             complement(16299..17561)
                     /locus_tag="VXC78_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV0582293.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(17871..18329)
                     /locus_tag="VXC78_000138"
     CDS             complement(17871..18329)
                     /locus_tag="VXC78_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV0582294.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(18326..18766)
                     /locus_tag="VXC78_000139"
     CDS             complement(18326..18766)
                     /locus_tag="VXC78_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0582295.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            19122..21071
                     /gene="mutL"
                     /locus_tag="VXC78_000140"
     CDS             19122..21071
                     /gene="mutL"
                     /locus_tag="VXC78_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV0582296.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(21396..21863)
                     /locus_tag="VXC78_000141"
     CDS             complement(21396..21863)
                     /locus_tag="VXC78_000141"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV0582297.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(21864..23069)
                     /locus_tag="VXC78_000142"
     CDS             complement(21864..23069)
                     /locus_tag="VXC78_000142"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV0582298.1"
                     /translation="MEYRKIQETLEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLIERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(23089..23724)
                     /gene="ribE"
                     /locus_tag="VXC78_000143"
     CDS             complement(23089..23724)
                     /gene="ribE"
                     /locus_tag="VXC78_000143"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV0582299.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(23709..24809)
                     /gene="ribD"
                     /locus_tag="VXC78_000144"
     CDS             complement(23709..24809)
                     /gene="ribD"
                     /locus_tag="VXC78_000144"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV0582300.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(24944..25058)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25215..25808
                     /gene="ruvA"
                     /locus_tag="VXC78_000145"
     CDS             25215..25808
                     /gene="ruvA"
                     /locus_tag="VXC78_000145"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV0582301.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            25818..26381
                     /locus_tag="VXC78_000146"
     CDS             25818..26381
                     /locus_tag="VXC78_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV0582302.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTETELEAMLENPAIIRNRAKLFATRANAQ
                     VLLQLQAEYGSFDAYLWSFVEGKIVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            26378..27055
                     /locus_tag="VXC78_000147"
     CDS             26378..27055
                     /locus_tag="VXC78_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0582303.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(27210..28241)
                     /locus_tag="VXC78_000148"
     CDS             complement(27210..28241)
                     /locus_tag="VXC78_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV0582304.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(28496..29179)
                     /locus_tag="VXC78_000149"
     CDS             complement(28496..29179)
                     /locus_tag="VXC78_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV0582305.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGSDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(29191..30135)
                     /locus_tag="VXC78_000150"
     CDS             complement(29191..30135)
                     /locus_tag="VXC78_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0582306.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            30267..33098
                     /gene="uvrA"
                     /locus_tag="VXC78_000151"
     CDS             30267..33098
                     /gene="uvrA"
                     /locus_tag="VXC78_000151"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV0582307.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            33091..34152
                     /locus_tag="VXC78_000152"
     CDS             33091..34152
                     /locus_tag="VXC78_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0582308.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            34284..34682
                     /gene="spx"
                     /locus_tag="VXC78_000153"
     CDS             34284..34682
                     /gene="spx"
                     /locus_tag="VXC78_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV0582309.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            34748..35317
                     /locus_tag="VXC78_000154"
     CDS             34748..35317
                     /locus_tag="VXC78_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0582310.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            35404..35670
                     /locus_tag="VXC78_000155"
     CDS             35404..35670
                     /locus_tag="VXC78_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV0582311.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            35674..36093
                     /gene="ruvX"
                     /locus_tag="VXC78_000156"
     CDS             35674..36093
                     /gene="ruvX"
                     /locus_tag="VXC78_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV0582312.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            36109..36414
                     /locus_tag="VXC78_000157"
     CDS             36109..36414
                     /locus_tag="VXC78_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV0582313.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            36672..37922
                     /locus_tag="VXC78_000158"
     CDS             36672..37922
                     /locus_tag="VXC78_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0582314.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            37919..38461
                     /locus_tag="VXC78_000159"
     CDS             37919..38461
                     /locus_tag="VXC78_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV0582315.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            38607..40139
                     /gene="cls"
                     /locus_tag="VXC78_000160"
     CDS             38607..40139
                     /gene="cls"
                     /locus_tag="VXC78_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV0582316.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            40217..40360
                     /locus_tag="VXC78_000161"
     CDS             40217..40360
                     /locus_tag="VXC78_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582317.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            40397..41935
                     /locus_tag="VXC78_000162"
     CDS             40397..41935
                     /locus_tag="VXC78_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0582318.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWGLHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            42055..44262
                     /gene="nrdD"
                     /locus_tag="VXC78_000163"
     CDS             42055..44262
                     /gene="nrdD"
                     /locus_tag="VXC78_000163"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV0582319.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            44274..44414
                     /locus_tag="VXC78_000164"
     CDS             44274..44414
                     /locus_tag="VXC78_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582320.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            44458..44964
                     /locus_tag="VXC78_000165"
     CDS             44458..44964
                     /locus_tag="VXC78_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0582321.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            44957..45547
                     /gene="nrdG"
                     /locus_tag="VXC78_000166"
     CDS             44957..45547
                     /gene="nrdG"
                     /locus_tag="VXC78_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV0582322.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            45544..46161
                     /locus_tag="VXC78_000167"
     CDS             45544..46161
                     /locus_tag="VXC78_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV0582323.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            46427..46735
                     /gene="rpsJ"
                     /locus_tag="VXC78_000168"
     CDS             46427..46735
                     /gene="rpsJ"
                     /locus_tag="VXC78_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV0582324.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            46952..47578
                     /gene="rplC"
                     /locus_tag="VXC78_000169"
     CDS             46952..47578
                     /gene="rplC"
                     /locus_tag="VXC78_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV0582325.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            47603..48226
                     /gene="rplD"
                     /locus_tag="VXC78_000170"
     CDS             47603..48226
                     /gene="rplD"
                     /locus_tag="VXC78_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV0582326.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            48226..48522
                     /locus_tag="VXC78_000171"
     CDS             48226..48522
                     /locus_tag="VXC78_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV0582327.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            48540..49373
                     /gene="rplB"
                     /locus_tag="VXC78_000172"
     CDS             48540..49373
                     /gene="rplB"
                     /locus_tag="VXC78_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV0582328.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            49477..49758
                     /gene="rpsS"
                     /locus_tag="VXC78_000173"
     CDS             49477..49758
                     /gene="rpsS"
                     /locus_tag="VXC78_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV0582329.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            49770..50114
                     /gene="rplV"
                     /locus_tag="VXC78_000174"
     CDS             49770..50114
                     /gene="rplV"
                     /locus_tag="VXC78_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV0582330.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            50127..50780
                     /gene="rpsC"
                     /locus_tag="VXC78_000175"
     CDS             50127..50780
                     /gene="rpsC"
                     /locus_tag="VXC78_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV0582331.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            50784..51197
                     /gene="rplP"
                     /locus_tag="VXC78_000176"
     CDS             50784..51197
                     /gene="rplP"
                     /locus_tag="VXC78_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV0582332.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            51207..51413
                     /locus_tag="VXC78_000177"
     CDS             51207..51413
                     /locus_tag="VXC78_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV0582333.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            51438..51698
                     /gene="rpsQ"
                     /locus_tag="VXC78_000178"
     CDS             51438..51698
                     /gene="rpsQ"
                     /locus_tag="VXC78_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV0582334.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            51724..52092
                     /gene="rplN"
                     /locus_tag="VXC78_000179"
     CDS             51724..52092
                     /gene="rplN"
                     /locus_tag="VXC78_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV0582335.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            52170..52475
                     /gene="rplX"
                     /locus_tag="VXC78_000180"
     CDS             52170..52475
                     /gene="rplX"
                     /locus_tag="VXC78_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV0582336.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            52499..53041
                     /gene="rplE"
                     /locus_tag="VXC78_000181"
     CDS             52499..53041
                     /gene="rplE"
                     /locus_tag="VXC78_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV0582337.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            53059..53328
                     /gene="rpsN"
                     /locus_tag="VXC78_000182"
     CDS             53059..53328
                     /gene="rpsN"
                     /locus_tag="VXC78_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV0582338.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            53613..54011
                     /gene="rpsH"
                     /locus_tag="VXC78_000183"
     CDS             53613..54011
                     /gene="rpsH"
                     /locus_tag="VXC78_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV0582339.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            54203..54739
                     /gene="rplF"
                     /locus_tag="VXC78_000184"
     CDS             54203..54739
                     /gene="rplF"
                     /locus_tag="VXC78_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV0582340.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            54823..55179
                     /gene="rplR"
                     /locus_tag="VXC78_000185"
     CDS             54823..55179
                     /gene="rplR"
                     /locus_tag="VXC78_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV0582341.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            55197..55691
                     /gene="rpsE"
                     /locus_tag="VXC78_000186"
     CDS             55197..55691
                     /gene="rpsE"
                     /locus_tag="VXC78_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV0582342.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            55663..55887
                     /gene="rpmD"
                     /locus_tag="VXC78_000187"
     CDS             55663..55887
                     /gene="rpmD"
                     /locus_tag="VXC78_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV0582343.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            56032..56472
                     /gene="rplO"
                     /locus_tag="VXC78_000188"
     CDS             56032..56472
                     /gene="rplO"
                     /locus_tag="VXC78_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV0582344.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            56485..57795
                     /gene="secY"
                     /locus_tag="VXC78_000189"
     CDS             56485..57795
                     /gene="secY"
                     /locus_tag="VXC78_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV0582345.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            57946..58584
                     /locus_tag="VXC78_000190"
     CDS             57946..58584
                     /locus_tag="VXC78_000190"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV0582346.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            58701..58919
                     /gene="infA"
                     /locus_tag="VXC78_000191"
     CDS             58701..58919
                     /gene="infA"
                     /locus_tag="VXC78_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV0582347.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            58944..59060
                     /gene="rpmJ"
                     /locus_tag="VXC78_000192"
     CDS             58944..59060
                     /gene="rpmJ"
                     /locus_tag="VXC78_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV0582348.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            59078..59443
                     /gene="rpsM"
                     /locus_tag="VXC78_000193"
     CDS             59078..59443
                     /gene="rpsM"
                     /locus_tag="VXC78_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV0582349.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            59461..59844
                     /gene="rpsK"
                     /locus_tag="VXC78_000194"
     CDS             59461..59844
                     /gene="rpsK"
                     /locus_tag="VXC78_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV0582350.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            59887..60822
                     /locus_tag="VXC78_000195"
     CDS             59887..60822
                     /locus_tag="VXC78_000195"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV0582351.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            60834..61220
                     /gene="rplQ"
                     /locus_tag="VXC78_000196"
     CDS             60834..61220
                     /gene="rplQ"
                     /locus_tag="VXC78_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV0582352.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            61485..61751
                     /locus_tag="VXC78_000197"
     CDS             61485..61751
                     /locus_tag="VXC78_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV0582353.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            61761..63098
                     /locus_tag="VXC78_000198"
     CDS             61761..63098
                     /locus_tag="VXC78_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV0582354.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            63342..64034
                     /locus_tag="VXC78_000199"
     CDS             63342..64034
                     /locus_tag="VXC78_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0582355.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(64137..65782)
                     /locus_tag="VXC78_000200"
                     /pseudo
     CDS             complement(64137..65782)
                     /locus_tag="VXC78_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(65772..66847)
                     /locus_tag="VXC78_000201"
                     /pseudo
     CDS             complement(65772..66847)
                     /locus_tag="VXC78_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(66860..67981)
                     /locus_tag="VXC78_000202"
                     /pseudo
     CDS             complement(66860..67981)
                     /locus_tag="VXC78_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(68179..68376)
                     /locus_tag="VXC78_000203"
     CDS             complement(68179..68376)
                     /locus_tag="VXC78_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0582356.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(68451..69227)
                     /locus_tag="VXC78_000204"
     CDS             complement(68451..69227)
                     /locus_tag="VXC78_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV0582357.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGKEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            69349..70095
                     /locus_tag="VXC78_000205"
     CDS             69349..70095
                     /locus_tag="VXC78_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0582358.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            70108..71088
                     /locus_tag="VXC78_000206"
     CDS             70108..71088
                     /locus_tag="VXC78_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV0582359.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            71283..71603
                     /locus_tag="VXC78_000207"
     CDS             71283..71603
                     /locus_tag="VXC78_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0582360.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            71649..71957
                     /locus_tag="VXC78_000208"
     CDS             71649..71957
                     /locus_tag="VXC78_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0582361.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            71974..73272
                     /locus_tag="VXC78_000209"
     CDS             71974..73272
                     /locus_tag="VXC78_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0582362.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGTIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            73423..75861
                     /locus_tag="VXC78_000210"
     CDS             73423..75861
                     /locus_tag="VXC78_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV0582363.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            75880..76548
                     /locus_tag="VXC78_000211"
     CDS             75880..76548
                     /locus_tag="VXC78_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV0582364.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            76566..77654
                     /locus_tag="VXC78_000212"
     CDS             76566..77654
                     /locus_tag="VXC78_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV0582365.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            78109..80610
                     /locus_tag="VXC78_000213"
     CDS             78109..80610
                     /locus_tag="VXC78_000213"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV0582366.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGDVKEAAYTEDGLHVNSDFLDELNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
BASE COUNT        24529 a        14727 c        17552 g        24187 t
ORIGIN      
        1 aaaaatttta gtatatgaac caaatttaaa cgttagtata gataacgtaa tttttgaaaa
       61 gaattttgaa ctatttacaa aacaaagtga tctaattgtt gcaaatagat gggatagggg
      121 ccttgaagct tataaagata aagtttacac aagggggatc tggataagag attaactatt
      181 gatattaaaa aggcaataat ttataaaatt tgtacaaaaa aatgttaaat tttcacattt
      241 tcatagtata ctgtttaata gaaagtaggt tctttgtaac cgctccatta taaaatcctt
      301 tcactcttcc ggtatactat taggaaaaac ataactggag gatattttga gctcacacct
      361 catcgttcca gtggctgttc cccaagctcg tgtactgccc aaaaaagtta gacattctat
      421 ttagaacgag gattgagttc tgtattgtac aaggctcggt ccttttagag tcagcttaag
      481 gctggctttt ttattttttc taactatcag aatattttga caaatgaaca caaataatga
      541 tataatatgc aaaagctagg aggtggtagg atgattgaaa aaatggaatt gggggaattt
      601 tacaaggaat tacgtttggc gagaaagctc aagcagtcag atgtggcttg tgacgggcta
      661 acagcttctc agttgtccaa gtttgagcta gggcagtcca tgttgtctgc tgataagctc
      721 atattagcca tccaagggat caatgtgacc tttgatgagt ttgggcacaa gctcaacaac
      781 tatcaagaat ctccacatat gcagattggt agaaaggttg tggatcgctt tgctcatcaa
      841 gatatagctg gcttagagca actgttggag gaagtcgagc aagaacagat ggcagagact
      901 tatcgtcgtt tgaatgctat tgtaatcaaa gatgccatcc actcactaga taaaagctac
      961 ccactagcag aggaggatag cgagtttttg accacctatc tctatgctat cgagtcttgg
     1021 acctggtttg aactctatct cttttgcaat actctgccct tcttgagcaa tcaagatctg
     1081 atctttttat caacctcctt actcgaaaaa tccaaagaat ttaaagagtt agtacacaat
     1141 cgattgtata tgaagcaagg actcttaaat atcatctcag agctcatgga gcgcaaactt
     1201 ttttcttata tcccaatctt tgaagccgag ctggagagta tgctccgtcc atacgatgtt
     1261 tttgagaaag tgttgtggca gtttttaaag aagatgagca ttttccttca aactaaggga
     1321 agcaatcaaa aagagattga acactttatc caatctctgc aagtattaga aaatccacaa
     1381 ttaatagccc tttttgaatt gcgtttgcag caatacaaaa agcttatcga ttagttagaa
     1441 atggcaaaat aataataatc tcagcaacga ttttcaataa tgttaaaatt tgtttcttca
     1501 tatttctcca ctcctcatta gtagtaactt tattatacca gagaagtaat caaattcacc
     1561 aaaatcgcaa atctgaaatt tctataagaa aaaatatcaa atatgcgatt ttctaaaata
     1621 agccaatttt cgtgttatac tgtacttgta aagcacttga agcaaatcct aggtcgcaga
     1681 agtggtttac aaatgaagat aattgaagga gtgtaaaaga tgttaaattt acaatttgca
     1741 gaaacaatgg aattgacaga agctgagttg gagatagttt atggagggga atttgggaat
     1801 aatgctgtta tcccagccgg tgcttgggga gggttcggga caccttggtc aatcactaat
     1861 ttctggaaga aaaattttaa cgatagacct gactttgatt ctgaccgccg tcgttattaa
     1921 tatccaaagc ccttgccttt tcttgggtag gggctgtctt tatttcatag tataggagga
     1981 aatagaatga aaaagataat ctcacaccgc tactttatta tagtttttct actagttatt
     2041 gctgaccaga agttcagtgt tctagtttta cgcagcgacc ttgttactgg gctatctgac
     2101 tttgcctatt atctgtcgga tatgatgttg aattttcttg tggttttatt tgctcttatt
     2161 gctatgattt ggtcggggaa atggcagaaa atcaatagta gaaagtttaa aggatcctat
     2221 cttttctatt ccttcctagc tctgcttgct tttgttgttt ggaatttcgt tacctttttt
     2281 cttttcccac ctactcgaaa tgaaatttct tatcaacatg ctgctccgac ttttacaggg
     2341 gctacagcat ttttgatgta ttttttctat cctgtgattg caggtcccat ttttgaagag
     2401 ataatccatc ggggattggt gatgacagct ctggaaaaag gaaagaaatg ggggctagat
     2461 gtacttggct ctgctatttt atttggggtc tcgcacatta gtaatcacgg ttgggtcttg
     2521 acagactttg tcttctatat gggtggaggt cttatatttg cagtcttatt tagaatgaca
     2581 aagtcaattt attggcctat tggactgcat atagtctaca atggtattgg tcagcttttg
     2641 atgttactgt aattttggtt gttagtagta tcgcggtcta ttcttgggga aagattccca
     2701 tttgaactta agaaggagtt gtaatgaaag tatttcttca aaatagagat tttaggcaat
     2761 taactatcaa ccagtggatt tcaacgcttg gggatacgat tttttatctg gccttcctga
     2821 attatgtggc agatgcgtct tttgcccctt tggcgatttt acttatcacg atttcagaaa
     2881 cccttcccca agttctacaa atctttctgg gagttttggc ggattttcaa catcatcgtg
     2941 tcttgaaata cacagtcatt agttttacaa aatttttgct ttactctata gtgtccctat
     3001 cgctttcagg gcagtctttt tccttgttgc tagtaacctt tatttgtatg attaacctct
     3061 tgtctgacac attgagttat ttttcaggcg ccatgctcac tccgattttc attagaatta
     3121 ttgggcaaga tcatctggca gaagctattg gatttaaaca gtcaactgtt agtttagtga
     3181 aaacaatcag taatatccta ggaggagtct tactaggtat tctatccatc cagtttattt
     3241 ccttactgaa cgctcttacc tttttaatcg catttttagg tatcctcttc ataaaaactg
     3301 acctcttgaa agtagaaaaa acgattagct atcaagaagg actctctgta aaatcctttt
     3361 gccagcattt gctccaatca tcgaaattga tatggaatat gaataaggtg ctcttggttt
     3421 tgtttattat ctctactagt caagcagtga taaatgttac agttcctgtc tctactctat
     3481 ttttgaggaa tcaacccttt ttgaatttac aaacaggtca atctcttgcc ttgctatcca
     3541 cttttgaact gtcagccctg attgtcggaa gccttgtaag tggctatctg caacatacca
     3601 tttccataaa aacaactctc tatgcctcac ttgtcatcca gttgcttctt ctagtaggat
     3661 ttgccacagt tcgttttgac tggattctca tctttagtac cttggatgcc tttttcgcag
     3721 gtgttctctc tcctagattg caagaactcg tctttaaaca aatacctgag gagtcaatgg
     3781 gagcagttca atcttctatc agtgccatta cggttgtttt acctagctta tttacaatat
     3841 ctttggtaac cattgctact agctttggaa ctctggcagt tagctttgtt ttattgctat
     3901 ttcttctagt tgcctttgtt atgcttctga atattcgtga aagtatttag tggagaattt
     3961 ctataatata tgtttgagac tggattgcca gtctttttat gatggtcaaa atcaacagac
     4021 tttttctctt ttctgaatgt gttatagtag actgaatcta aaatagtacg aaacaattgc
     4081 taaaacattt atagaaatta attttacttt cccaatcgat ttgttctcat cttatttcaa
     4141 tctgctatat aatagtccat gctgtggctg gattcttttc agcctactta tactcttcga
     4201 aactctcttc aaaccacgtc agcttcacct tgccgtatat gtgttactga cttcgtcagt
     4261 tctatccaca acctcaaaac agtgttttga gctgacttca tcagttctat ctgcaacctc
     4321 aaaacagtgt tttgagcaac ctgcggctag tttcctagtt tgctctttga ttttcattga
     4381 gtattattaa gacaatatga ggagaaagat gaaagaaaaa ggattttagg agggggcgca
     4441 ggcagccatg ccaacggctc ttggctatgt cagtatcggc ctggcctgtg gaattatcgg
     4501 tgcgccctat gtgacacctg ttgagatggg cttgatgagt ctctttgttt atgctgggag
     4561 tgcccagttt gccatgttgg cactgattgt ggttcaagct cctgtggcag ctattgctat
     4621 gacggttttt ctaatcaatt tgcgtctctt tttgttgagc ttacacgcat cgacttattt
     4681 ccgtcatacc agtctttggc acaatatcgg tatgtctagt atcttgacag atgagaccta
     4741 tggcgttttg atgggcgaat tagcccatac agataaggtc aatccgatgt ggatgcacgg
     4801 gaacaatctc aacagctatg tggcttggtt tgtgggaaca gtggtcggaa cggctctagg
     4861 tgacctgttg ccaaatccag aaatctttgg tttagatttt gccctggttg ggatgtttat
     4921 cgggattttt gcttcgcaat tccagatgat gcaaagacgg atttctgtcc gcaatctgct
     4981 cattatctta gcagttgttg cagtgtcctt ctttttactt ttgacagtgg tgtctcagtc
     5041 actagctgtt ctgtttgcga cgctacttgg ttgtagcatg gggatggttt tagatggtca
     5101 gtaagtatct tttattagca gttattttct ctggtcttgt gacctggatt ccccgtatga
     5161 ttcccttcat cttggtcaag tataagggcc tgcctacgat tgttgagcgt tttttgaagt
     5221 ttttgcctgt ttccattatc tttgccttga ttctttcaag agtagtgaca ggtaaggttg
     5281 ggaaccttcc tcaaatcaaa tgactggact tcttagcagt ctttccaaca gcttgggtag
     5341 cttttcgcta ccgcaatcta gtcggtacgg ttctctttgg agtagtcttg attgccgtct
     5401 tgcgtttggt cttttaaata agtcataaag aaaacttatc acagagatag atatcatata
     5461 atggcgtaat tacttttttt ctgataagat tataaggtat tctattttgg aggaaatgac
     5521 atgaaaaaaa tcgttaaata ctcatctctt gcagcccttg ctcttgttgc tgcaggtgtg
     5581 cttgcggctt gctcaggtgg tgctaagaaa gaaggacaag cagctagcaa gaaagaaatc
     5641 atcgttgcaa ccaatggatc accaaggcca tttatctatg aagaaaatgg cgaattgact
     5701 ggttacgaga ttgaagtcgt tcgcgctatc tttaaagatt ctgacaaata tgatgtcaag
     5761 tttgaaaaga cagaatggtc aggtgtcttt gctggtcttg acgctgaccg ttacaatatg
     5821 gctgtcaaca atcttagcta cactaaagaa cgtgcggaga aatacctcta tgccgcacca
     5881 attgcccaaa atcctaatgt ccttgtcgtg aagaaagatg actctagtat caagtctctc
     5941 gatgatatcg gtggaaaatc gacggaagtc gttcaagcca ctacatcagc taagcagtta
     6001 gaagcataca acgctgaaca cacggacaac ccaactatcc ttaactatac taaggcagat
     6061 ttccaacaaa tcatggtacg tttgagcgat ggacaatttg actataagat ttttgataaa
     6121 atcggtgttg aaacagtgat caagaaccaa ggtttggaca acttgaaagt tatcgaactt
     6181 ccaagcgacc aacaaccgta cgtttaccca cttcttgctc agggtcaaga tgagttgaaa
     6241 tcgtttgtag acaaacgcat caaagaactt tataaagatg gaactcttga aaaattgtct
     6301 aaacaattct tcggagacac ttatctaccg gcagaagctg atattaaata atttcttgaa
     6361 atcatccatt ctgagtaaga tgggtggttt ctcagttttt agggatatag ttttaaacta
     6421 tatatctgac tatctaataa caatttgtga aatcaaacaa attgtgagat actagtacgg
     6481 tattattttt aaggagaaag aatcatgaaa atcaaaaaat ggcttggtct agcagccctt
     6541 gctacagtcg caggtttggc tcttgcagct tgcggaaact cagaaaagaa agcagacaat
     6601 gcaacaacta tcaaaatcgc aactgttaac cgtagcggtt ctgaagaaaa acgttgggac
     6661 aaaatccaag aattggttaa aaaagacgga attaccttgg aatttacaga gttcacagac
     6721 tactcacaac caaacaaagc aactgctgat ggcgaagtag atttgaacgc tttccaacac
     6781 tataacttct tgaataactg gaacaaagaa aacggaaaag atcttgtagc gattgcagat
     6841 acttacatct ctccaatccg cctttactca ggtttgaatg gaagtgccaa caagtacact
     6901 aaagtagaag acatcccagc aaacggagaa atcgctgtac caaatgacgc tacaaacgaa
     6961 agccgtgcgc tttacttgct tcaatcagct ggcttgatta aattggatgt ttctggaact
     7021 gctcttgcaa cagttgccaa catcaaagaa aatccaaaga acttgaaaat cactgaattg
     7081 gacgctagcc aaacagctcg ttcattgtca tcagttgacg ctgccgttgt aaacaatacc
     7141 ttcgttacag aagcaaaatt ggactacaag aaagcacttt tcaaagaaca agctgatgaa
     7201 aactcaaaac aatggtacaa catcattgtt gcgaaaaaag attgggaaac atcacctaag
     7261 gctgatgcta tcaagaaagt aatcgcagct taccacacag atgacgtgaa aaaagttatc
     7321 gaagaatcat cagatggttt ggatcaacca gtttggtaat aagaaacagg gaggtgggag
     7381 agaaaattcc acctcttgct tttgtataga gtatagattg taaagaagac tattcgttca
     7441 tagaaaggta gagagaatat ggtttttcct agcgaacaag aacagattga aaaatttgaa
     7501 aaggatcatg tagtccaaca ttattttgag gttttgcgta ccttgatttc taagaaatca
     7561 gtctttgccc agcaggttgg actcaaggaa gtcgcaaatt atctgggtga gattttcaag
     7621 cgtgttggag ctgaagtgga gattgatgag agctatacag cgccctttgt catggcacat
     7681 ttcaagagtt cgcgtccaga tgccaagacc ttgattttct ataaccacta tgacactgtg
     7741 ccagcggatg gggatcaggt ctggacagag gatcctttta cgctttcggt ccgcaatggc
     7801 ttcatgtatg ggcgtggggt tgatgacgac aagggtcata tcacagctcg cttgagtgct
     7861 ttgagaaaat atatgcagca ccatgatgat ttacctgtca atatcagctt tatcatggag
     7921 ggagcggagg aatcggcttc aacagaccta gataagtatt tggaaaagca tgcagacaaa
     7981 ctccgtgggg cggatttgtt ggtctgggaa caagggacca aaaatgcctt ggagcagctg
     8041 gaaatttctg gtggcaataa ggggattgtg acctttgatg ccaaggtaaa aagcgctgat
     8101 gtggatatcc actcgagtta tggtggtgtt gtggaatcag ctccttggta tctcctccaa
     8161 gccttacagt ctcttcgtgc tgcggatggc cgtatcttgg ttgaaggctt gtacgaagaa
     8221 gtacaagagc ccaatgaacg agaaatggcc ttgctagaaa cttatggtca acgaaaccca
     8281 gaggaagtta gtcggattta tggattggag ttgcctctct tacaggagga gcggatggcc
     8341 tttctaaaac gtttcttttt cgagccagcg cttaatatcg aaggaatcca gtctggttat
     8401 caaggtcagg gtgttaagac tattttacct gcagaagcca gtgccaagct agaggttcgt
     8461 ctggttccgg gcctagaacc gcatgatgtt ctggaaaaaa ttcggaaaca gctagacaaa
     8521 aatggctttg ataaggtaga attatactat accttgggag agatgagcta tcgaagcgat
     8581 atgagcgcac cagccattct caatgtgatc gagttggcca agaaattcta tccacagggc
     8641 gtttcagtct tgccgacgac agcggggaca ggacctatgc atacggtctt tgatgcccta
     8701 gaggtaccaa tggttgcatt cggtctagga aatgccaata gccgagacca cggtggagat
     8761 gaaaatgtgc gaatcgctga ttatcacacc catatcgaat tagtagagga gctgattaga
     8821 agctatgagt agagatatta tcaagttaga tcagatcgat gtgacttttc accaaaagaa
     8881 gagaaccatt acagcggtta aggatgtgac cattcacatc caagaagggg atatctacgg
     8941 aatcgttgga tattctggag caggaaaatc aacccttgta cgggtgatta atctcttgca
     9001 aaaaccatct gcagggaaaa ttaccattga cgacgatgtg atttttgacg gcaaggtgac
     9061 cttgacggca gagcagttgc gtcgtaaacg tcaagatatc ggaatgattt tccagcattt
     9121 taacctgatg agccaaaaga cagcagagga gaatgtagcc tttgccctta aacactctga
     9181 actcagcaag gaagaaaaga aggctaaagt agctaagttg ttggacttgg ttggtttggc
     9241 agatcgtgct gaaaactacc cttcacaact atctggaggg caaaaacagc gtgtggcaat
     9301 tgcgcgtgcc ttggccaatg atccaaaaat cttgatttca gacgagtcaa cttctgccct
     9361 tgatccgaag acaaccaagc agattttggc cttgttgcaa gatttgaacc aaaaattagg
     9421 cttgactgtt gtcttgatta cgcatgaaat gcagattgtc aaagacattg ccaaccgtgt
     9481 ggcggttatg caggatgggc atttgattga agagggtagt gtgcttgaaa tcttctcaga
     9541 ccctaaacaa cctttgactc aagactttat ctcaacagct acaggtattg acgaagccat
     9601 ggtcaaaatc gagaagcaag aaatcgtgga acacttgtct gaaaacagtc tcttggtgca
     9661 actcaagtac gctggatctt caacagacga gccacttttg aatgaattgt acaagcatta
     9721 tcaagtaatg gctaatattc tctatgggaa tatcgaaatc ctcgatggta ctcctgttgg
     9781 agaattggtg gtggtcttgt caggtgaaaa agcagcgttg gcaggtgccc aagaagccat
     9841 tcgtcaagca ggcgtacagt taaaagtatt gaagggagga cagtaagatg gaatcattga
     9901 ttcaaaccta tttgccaaat gtctataaga tgggttggtc tggtcaggca ggctggggaa
     9961 cagctatcta cctaaccctc tatatgacag ttctttcctt cattatcgga ggcttcttgg
    10021 ggctagtggc aggtctcttt ctcgtcttga cagcgccagg tggtgtcttg gagaataaag
    10081 tcgtattctg gattttagac aaaattacct caatttttcg tgcgattccc tttatcatcc
    10141 tcttggcaat cttgtcacca ctttctcact tgattgttaa aacaagtatc gggccaaatg
    10201 cagcccttgt cccactttct tttgcagtct ttgccttctt tgcccgtcag gtgcaggttg
    10261 tcttggctga attggatggc ggtgtcattg aggcggctca agcgagcgga gcgactttct
    10321 gggacatcgt gggtgtttac ctatcagaag gtcttccaga tttgatccgt gtgacgactg
    10381 tgaccttgat ttcccttgtt ggggaaacag ctatggccgg tgcggttgga gctggtggta
    10441 tcggtaacgt agccatcgct tatggattta accgctacaa tcacgatgtg accatcttgg
    10501 caaccattat tatcattttg attatctttg caatccaatt cttgggagat ttcttgacta
    10561 agaaattgag tcataaataa aaagagccgc gtggctcttt ttaactgatc agattttctg
    10621 tgcaaatttt ttactcaagg cttgtccaat caaggcaccc actagggctc cgatgacaat
    10681 acttgcgata aatagaagga cagttccagg gtttggagcg accatgatac ggtcgatata
    10741 ttcttgggat tttcctcttg ccagaagagt agccatatag gctttgggcg caatccacat
    10801 aagcaagatt ggtcctgttg tactaaaggc gaaaataatg aaagaaagga agttctttgt
    10861 tttgtccttg tattttccta aatgagctac ttcatctgct aggaggccac agataattcc
    10921 aggaaggaag gaaccagcac cgtgtttagt tcccaagaaa aagagggcaa tgacaaggcc
    10981 gatagtggta atggctccaa agcgcggaac ttttgcgact aggatcatat agacgctacc
    11041 gccgacaagg gcagtaaagg caggcgcata aaacatgttt ccagtttggt caaagagatt
    11101 gcccaaaagg acaccaatcc ccatgcagag gaagtaaaga actgcaaaaa gcagtgtagt
    11161 taagatagat ttcttcatga attgtctcct gataattttt tcacaattct cattgtacca
    11221 cggtttggtg ggattgtaaa tggatactag aagtttttga aaacgcttga aatatgatat
    11281 aatggtttca tagttatttt taggggaata tcatgggtag atttttagac tttgtcttta
    11341 atcgtttctt tttagggatg attgcgacag ccttcttttg gctattaact ttagcaggag
    11401 ggattatcct tggtctagcg ccggctagtg ccaccttgat gagcttatat gcagaacatg
    11461 gttatagctt tcgggaatac agtttgaagg aggcttggtc tctttacaag caaaattttg
    11521 tctcaagcaa cctgattttc tatagctttt taggtgtggg tctagttttg acctatggtt
    11581 tgtatctctt ggtgcaattg cctcatcaga ccattgttca tttgattgcg acccttttga
    11641 atgtcctagt agttgccctg atctttttgg cttatacagt atctttaaaa ttacaagttt
    11701 attttgcctt gtcctatcga aatagtctca aattatcctt gattggcatc tttatgagtc
    11761 tagcagctgt ggccaagatt ctccttggga ctgtgctact tgtagcaatt ggttactata
    11821 tgcctgccct gctatttttt gtaggaattg ggatgtggca tttctttatc agtgatatgt
    11881 tggaacctgt ctatgaaatc atccatgaaa aattggcgac aaaatagaat gaagcagttt
    11941 tggctacata cgcttctaag aacctatagt tcagtgatga tcattatcat tgcgagtttt
    12001 gcaatcttac tctcttacgc tgactgggat tcacgtgaaa aggaagccca gagagtagcc
    12061 cagcgtgtaa ctgctagaac agtgagtgaa attgaatatt accatagaga gtcaacccag
    12121 atagctcagg ctttagttga aaaccaagct cgtattgagg gaatctataa atactttagt
    12181 cttagcatgc cagactattt ttactggcaa ttagagcgga aagcttcgcc ttatatatca
    12241 gtctctctgt atgaaaatgt tgatgacctc tatgttcgaa atgattttgt aactggagtg
    12301 gccattgctt ttcaagatta caaggaagtc tatgtttcta ctaaagacaa acgtagtgga
    12361 gaaaaaatca gggctgagga tttcaaacca gcaggaaata gttttgccat tccggtgtca
    12421 gatccagtgt cagatcaaga tttaggagtg atttacatct ccttggatcc tgctgtttta
    12481 taccatgcca ttgataatac tagaggtcat actccgatgg cagtaacagt gacctcacct
    12541 tttgatacgg agatttttca tattggtgag acagttgata aggagagtga aaattggcta
    12601 gttggcttaa cttctcatgg atatcaggtt caggtggcag ttcctaaaaa ctttgtttta
    12661 caaggaacag tgactagctc tgctttgatt gtgggtttga gccttctctt tattgtcatt
    12721 ctttatctga ctttgaggca gacttttgct aattaccaaa agcaggtagt ggatttagta
    12781 gaatccattc aagtcattgc tcaaggcgaa gaggggcgtc ggattgacat ttccgagaaa
    12841 gatcaggaat tactcctaat cgcggagacg accaatgata tgttggatcg attggaaaag
    12901 aatatccatg atatttacca gttagagctt agtcaaaaag atgccaatat gcgagccttg
    12961 caggcgcaaa tcaatcctca ttttatgtat aatacgctgg agttcttgcg catgtatgca
    13021 gttatgcaga gtcaagatga gttggcagat atcatttatg aattcagtag tctcttgcgt
    13081 aacaatattt ccgacgaaag agagaccctc ctcaaacagg aattagaatt ttgccgtaaa
    13141 tacagctatc tctgcatggt tcgctatccc aagtccattg cctatggttt caagatagat
    13201 ccagagttag agaatatgaa gattcccaag tttaccttgc aaccgctggt agaaaactat
    13261 ttcgcgcatg gtgttgacca caggcggaca gataatgtga ttagcatcaa ggctcttaaa
    13321 caggatggtt ttgtggaaat tttggtggtc gataatggta gaggaatgtc ggctgaaaag
    13381 ttggcaaata tccgagaaaa attaagtcag agatattttg aacaccaagc cagctacagt
    13441 gatcaaaggc agtctatcgg gattgtcaat gtacacgagc gttttgtgct ctattttgga
    13501 gaccgctatg ccattacgat agagtctgca gagcaagccg gtgttcagta tcgtattaca
    13561 attcaagatg agtagaaagg gagaaaatgt ataaagtatt attagtagat gatgagtaca
    13621 tggtgacaga aggtctgaag cgtttgattc cctttgataa gtgggatatg gaggtcgtcg
    13681 caacagccag tcatgccgat gaagctctag aatatgttca ggaaaatcct gtcgatgtca
    13741 tcatttccga tgtcaatatg ccagacaaaa cagggcttga tatgattcgg gagatgaaag
    13801 agatcttacc agatgctgcc tatatcctgc tctcaggtta tcaggagttt gattatgtaa
    13861 aaagagcaat gaaccttagt gtggtggact atttggtcaa gcctgttgat aaggtagagc
    13921 tgggaaatct gctggagaag attgcaggtc agctcggcga gagagggaag aaaagtcaga
    13981 ctcttagtca agaattagac gaggctggat ttgttagtta tttaggggat aaggagaatt
    14041 ggtggatagg tctatccaag gaaaaacaag gttccttcgc cattccctac tatgtcttgg
    14101 gccaagactg gcagattttc atttctgacc aacccctaga tggtttagtc gttacacctt
    14161 ttgaagctcc ttatcaagaa cactttgaac gctggaagct gaatgctgag aaaaccctct
    14221 tttacggttc tgtaaatctg cagcagtctg agagtctctt tgcctattac gaaccgattt
    14281 atagggttat cattcaggga aatctcaatc aaatcgtaga agagttaaat ctcttggaga
    14341 aggtagttct tgaaaatacg ccgcgtgttc cgattactaa acagcttttt attcagtttg
    14401 tcatggatgt tttccattta tttgaacatc tcaaagctga tgacctgaca gacatcgtca
    14461 aaaccattca tgctattcaa tccttcgatg aattggttcc ttatatcaag gaaactctga
    14521 ccagcttttt cggtcaatac cgtatgaatg aaaatgtggt cagtgtgctg gaagtcattg
    14581 gtcgtgatta ccaaaaagag ctttccctca aggatatcag taaggctctc tttatcaatc
    14641 ctgtctatct agggcagttg attaagcgtg aaaccgattc gacttttgca gagttactaa
    14701 acaaacaacg tattaaggct gcccaacaac ttttgctttc aactagtgac agcatcgaag
    14761 atatttgtta tgctgttggt tacagtaacc ttggatattt ctataaagtt tttcgaaaat
    14821 tgtgcggaaa atcgccaaaa gcctaccgaa aacaggtaga aactatacta taagatttgt
    14881 attcctttac aaaaggtgct ataatattat caggaggttc tatcatgaaa aagaaaccaa
    14941 tttatctatg ggtcttgcta atcttgtctg cccttatttc agttccgtct ctgtttggaa
    15001 ttgtgagtcc cttgcctagt aaagaagccc ttcgtgctgc tcagaaacaa gttgcagggg
    15061 tcaatgctca gcaattagaa gaccagctta attataccta tagagtagca gaagcatctc
    15121 attctatttt taatgttgct ttgattgtgc tatctactat tttagtggtc gtagcgattg
    15181 tcttccttgt tcgtaaaaat ttgcaatatg caaactatac ttacgttggt tatgttttgt
    15241 tagctattat tggttcgatt tatggctatg ttggtttaca agacgctgtg cagttggttc
    15301 aagatgagag catgcgtttg acagtgagta ttggttcaaa agctgttagc attttctata
    15361 tcgtcatcaa tgttctcttc ctagcccttg tcttctataa gatgtggcga caacagaaag
    15421 ccttggcaga agaagaggaa acagaagagc ttacctaagt attgacaaaa aagaactatc
    15481 aagatacaat cttggtagtt gttttttgat tatagataaa atcatggagg tacatatgaa
    15541 gacaatttct ttagtttata ttagtttgag tggcaacact gaaagttttg tgacgcgctt
    15601 gaaagactat ctcttgtccc agtacaaagg gattgaggtt caaaagattc atatcaagga
    15661 tttagtcaag gaaggcaaaa atttctatga aatggaccat ccctatgtcg cttttttgcc
    15721 gacctatctc gaaggtggga atggcgtgga taacggagat gttgagattt tgacgacacc
    15781 ggtgggagat tttattgcct atggtaacaa tgctagtaag tgttttggtg tggttgggtc
    15841 aggaaatcgt aactttaata accaatactg cctaacagcc aagcaataca gtcaacgctt
    15901 tggcttccct gtattggctg actttgaaat gcgaggcatg ctggaagata tcaaacatgt
    15961 cgcagctatt atcgcagatt tgtatgagtt ggaaaaggag aattaatact caatgaaaat
    16021 caaagagcaa actaggaagc tagtcgcagg ttactcaaag cacagctttg aggttgcaga
    16081 tagagctgac gtggtttgaa gagattctcg aatagtataa agttcttata agaggtggtt
    16141 gaagttgttc aactgttttt tgagtataaa cagtctttaa gaacgtaaaa aagcataagt
    16201 tcaggtcttc aaaaccttgt tcttatgctt tttatcatag aaatatttgc tgaattttct
    16261 cttgaaatga aaccttatct tcatctcgcg cttgtccctt accctgcttt tccgattgcg
    16321 agtgcgtaga taaagaagat ggcgaagcca aagaggaaaa tcaatcccgc aatggcaagg
    16381 tgtttgagcc aagaaggaag atttttgttt tcacgcgtta ccaaggcgta attcaaaaga
    16441 gcaaagaaag gtgttgtcag gaaagagcca atcatggcaa agcggagcat ggttgaaacc
    16501 tgaccagcga agaacttgat aatgacgata ccgatgatag cagtgatggt catccagatg
    16561 ttcaaagatt tacgattgtc ctctttttga ctgattagca gtcggagaga ttcctgatta
    16621 acgcgagaat agccatcgat aacagttata actgttccaa agatacagag gaaggcaata
    16681 aaggtaatca agtaacggga ccattcgcca agaacagagg catacatacc cacgaattga
    16741 gagatgtatt tggctgaagc agcttcaacc gcctgccctg taggatactg aatcagtgct
    16801 cccagtgcca caaagaagac ggctaggata gctgttccaa tataaccagt gttaaagtca
    16861 aacagagcgt cttctgtgtt aaagttgacg gtctttctct tttcagctga ccaaagtgaa
    16921 ttgatagctg aaatttcaat aggagccggc atccatccta ggagggagac gatgaagggc
    16981 agagctgcca tttgccaagg tgtcttctcg acaaaatcag aactgtattc tggatgcttg
    17041 accgccgcaa tgataactgc aagaacagtc gcaatggtta aggcagacat aatccatttg
    17101 accatgccgt ctaaaagttt gtagcctcca aagagtagca tagcccaaat gattgcaacg
    17161 agaatgaggg accactgagt aatgctaagt ccaatcattg ggaaggcact ggcgatgata
    17221 gctgagcaca gaatggcaac accagccgtg ttgaccatag ccgaaaagac attgaggata
    17281 aagaaaatcc agagatagag ttttcctttt tcggcataac cttcaaccaa agtctttcca
    17341 gtatcagctg tgtattcagc accaaaacgg aaaaatggat atttaaagac attggctaag
    17401 atgaccaaga gaagtagaga ccaaccgtaa gaaccgccag cttgagttga ggatacaatg
    17461 tgggaacctc caacagcggc agttgccatt aggattccag gtcccattgc ttttagcttg
    17521 cttgcccagg ttgattgatt taaggaaata gcttgcgaca tgataaatac tcctttttga
    17581 attttcagaa taatctgtat atgtaatcta tattctacaa aaaattttgg aaaaatgcaa
    17641 gagtattttg aaaaaagata gaaaatttac aaagaagatc tgaaataact gttatgatat
    17701 agaggattga aactagaata gtacacctct gcttctaaaa cattgttaga aatcgatttg
    17761 actgtcctga tcgatttatc ctgttcttat ttcatttcac tatagtaagg tgcagcagga
    17821 taaagaaaaa ccgagaagtt tctttctcgg atttgcttat tatgaggttc ctattttcta
    17881 tgctccaaga gttgattgat gtgatctact tttttagcct ctcttttata gagaatagcc
    17941 cagatgatga gatagacaat cgcaaactcg ataatgagct ggaggtagaa aatccagtgg
    18001 aaagggaacc aaccagcaag agttgctagt gggacaaagc cagccagcat aaggaagaaa
    18061 tgagtcagag tggcacgaag catgctccag tcacggctaa ataagcggtt gccaaagttg
    18121 aagagcatac cgatggttgc ccagataagt gtgcagtaga gcaagaccag ggcaccgtga
    18181 acctgatgct gatccatcac ttggcctatg agagagtagg gatttagtgg tgcgtaggta
    18241 tttggtgcat aaatgagtga aaagaggata gagaggatga ggccgataag aacaccggta
    18301 gctgcatcgt gaaatacttg ttttttcata gttctaattt ctccttgatg gtttttagat
    18361 aacggcgtga agagtaggtg aagctttcgt ttttcaagaa aatttctacc agaccgtttg
    18421 gcgtgagctt gaggtgagag atggaatcga tattgatgat ttctgattgg gaaatttgga
    18481 taaaattgct tggcaagagt ttaagaacct gatagagtcg caaatcaatg ctgtaggtct
    18541 gactcgcggt ttctgctaga accttccgat tctcgatata gaagcgctga atcttgccaa
    18601 tctcaactag atagacctga tcatcgattt ttcctttgat tttttctctt tggtccagat
    18661 tttctgcgaa ctcgatgact ttctggactt tttcggtttc ttgaggtgct tggacaatca
    18721 gcttttcctc ctcgtaagtc tcactaatct gtagttctac tttcataaat ttctctcctt
    18781 gtttttcata caaaattaat ctcacttctt gtacaccttt attaatactc ttcaaaaatc
    18841 tcttcaaacc acgtcagcgt cgtcttgccg taggatagtt gttgactttg tcagttttat
    18901 ctacaacctc aaaacagtgt tttgagctgt ctgcgtctag ctttctagtt tgctctttga
    18961 tttttattga gtataccact attttactcc ctctggcaag ggactttgtc tatgtggagg
    19021 gattgggctc ctatgtggtg gagtttttct gttctttctg aaatatggta taatagcact
    19081 aattaatttc taggaaaata gatacagaaa ggggctgaaa gatgtctcat attattgaat
    19141 tgccagagat gctggcaaac caaatcgcag ctggggaggt cattgaacgt cctgccagtg
    19201 tggttaaaga gttggtagaa aatgccattg acgcgggctc tagtcagatt atcattgaga
    19261 ttgaggaagc tggtctcaag aaggttcaaa tcacggataa cggtcatgga attgcccacg
    19321 atgaggtgga gttggccctg cgtcgccatg cgaccagtaa gataaaaaat caagcagatc
    19381 tctttcggat tcggacgctt ggttttcgtg gtgaagcctt gccttctatt gcgtctgtta
    19441 gtgtcttgac tctgttaacg gcggtggatg gtgctagtca tggaaccaag ttagtcgcgc
    19501 gtgggggtga agttgaggaa gtcatcccag cgactagtcc tgtgggaacc aaggtttgtg
    19561 tggaggatct ctttttcaac acgcctgccc gtctcaagta tatgaagagc cagcaagcgg
    19621 agttgtctca tatcattgat attgtcaacc gtctgggctt ggcccatcct gagatttctt
    19681 ttagcttgat tagtgatggc aaggaaatga cgcggacagc agggactggt caattgcgcc
    19741 aagcaatcgc agggatttac ggtttggtca gtgccaagaa gatgattgaa attgagaact
    19801 ctgacctaga tttcgaaatt tcaggttttg tgtctttacc tgagttgact cgggctaacc
    19861 gcaattatat cagcctcttc atcaatggcc gttatatcaa gaacttcctg ctcaatcgtg
    19921 ctattttgga tggtttcgga agcaagctta tggttggacg ttttccactg gctgtcattc
    19981 acatccatat cgacccttat ctagcggatg tcaatgtgca tccaactaag caagaggtgc
    20041 ggatttccaa ggaaaaagaa ctgatgaccc tggtttcaga agctattgca aatagtctca
    20101 aggaacaaac cttgattcca gatgccttgg aaaatcttgc caaatcgacc gtgcgcaatc
    20161 gtgagaaggt ggagcaaact attctcccac tcaaagaaaa tacgctctac tatgagaaaa
    20221 ctgagccgtc aagacctagt caaactgaag tagctgatta tcaggtagaa ttgactgatg
    20281 aagggcagga tttgaccctg tttgccaagg aaaccttgga ccgattgacc aagccagcaa
    20341 aactgcattt tgcagagaga aagcctgcta actacgacca gctagaccat ccagagttag
    20401 atcttgctag catcgataag gcttatgaca aactggagcg agaagaagca tccagcttcc
    20461 cagagttgga gtttttcgga caaatgcacg ggacttatct ctttgcccaa gggcgagatg
    20521 gactttacat catagatcag cacgctgctc aggaacgggt caagtacgag gagtaccgtg
    20581 aaagcattgg caatgttgac cagagtcagc agcaactcct agtgccctat atctttgaat
    20641 ttcctgcgga tgatgccctg cgtctcaagg aaagaatgcc tctcttagag gaagtgggcg
    20701 tctttctagc agagtacgga gaaaatcaat ttattctacg tgaacatcct atttggatgg
    20761 cagaagaaga gattgaatca ggcatctatg agatgtgcga catgctcctt ttgaccaagg
    20821 aagtttctat caagaaatac cgagcagagc tggctatcat gatgtcttgc aagcgatcta
    20881 tcaaggccaa tcatcgtatt gatgatcatt cagctagaca actcctctat cagctttctc
    20941 aatgtgacaa tccctataac tgtcctcacg gacgtcctgt tttggtgcat tttaccaagt
    21001 cggatatgga aaagatgttc cgacgtattc aggaaaatca caccagtctc cgtgagttgg
    21061 ggaaatatta aaagtataaa aaagtctggg aaaaattttc aaaatcagaa aaacgcataa
    21121 aatcaggtgt tcaaaaacct tgattttatg cgttttatca tggaaatagt tacttcatgt
    21181 tttcctaatt cttttcgaaa ctctttttaa accacgtcag ttttatcagt aatctcaaaa
    21241 cagtgttttg agctaatttt gccagttttg tctgtaacat cgaagttgtg ttttaccact
    21301 ctgcgactgg tttcctagtt tgctctatga ttttcacaga gtattaaatt gcgattttgc
    21361 caagtttctt tattcgtcta aaagtagagt ctgttctatg cgtctaatgt acgaattagg
    21421 ttgaccattt caatagctcc ttgtgcacac tcagaaccct tatttcctgc tttggtacca
    21481 gctcgttcta tggcttgttc aattgtatct gtcgttagca caccaaacat aacaggaatt
    21541 tcgctattta aactgatttg ggcgattccc ttagatacct cgctacatac ataatcataa
    21601 tgacttgtat tccctctaat gacagctccc aagcagataa ttgcatcata ttttttactt
    21661 tttgccattt ttgatgcaat cagtggtatt tcaaaagctc ctggaaccca ggctacctct
    21721 atatctttct cgtttacatt ctctcttttg agattatcta gtgctccaga taataatttt
    21781 gaagttataa attcattaaa tctcgctaca acaataccta ttttaatatt gtttgctact
    21841 aaattacctt cataagtgtt catttatttt tcctccatat ttaaaatgtg acccattcga
    21901 tttttctttg tttctaaata aaaactatcg taaggattgg cttctatttc gattgatatt
    21961 ctactggaaa tggtaattcc atatttttct aactgttcaa ccttgtcagg attatttgtc
    22021 agtaaatgaa gtgactgaag tcccagatct ttaagcattt gtgctccaat atgatattct
    22081 cttaaatcac cttcaaagcc taatgcaaga ttggcatcaa gcgtatccat gccttgatct
    22141 tgtaaatgat aggcttttaa tttattgata agtccaattc ctcgtccctc ctgtcgcaag
    22201 taaagtaaga cacccgaacc attctcaaca atcattttca tagctttatc gaattgctgt
    22261 ccacaatcgc aacgtaaaga gcctaaaaca tctcctgtta aacattcgga gtggacccga
    22321 cataatacat tggcttcatc ctctatgttt cccataataa gagcaagatg atgttcccca
    22381 tttagtttat ctatatagct aattgctttg aaattaccgt atctagtagg catattgaca
    22441 gttgaaactc gttctatcag ctgatcatat acttttctat attcttgtaa ttctttgatg
    22501 gtaattagtg gaatgttgtg tttcttcgag aactgaatta aatcatctgt tctcatcatt
    22561 ttgccatcat gattcattat ttcacaacat aggccacact cttttagtcc agctaatttt
    22621 aataaatcaa cagttgcttc tgtgtgtcca tttctttcta gaacaccacc tttttttgca
    22681 attaaaggaa acatgtgtcc tggcctgcga aaatcagagg gtgttatatc ttcagctaca
    22741 cacatacgtg cggtcagtcc tctttcctcg gcagaaatac ctgtggtcgt ttctttataa
    22801 tcaattgaaa ctgtaaaagc agtcttatga ttatctgtat tgttttcaac cataggtgaa
    22861 agcattaatt gattagctaa actttcgctc ataggcatac aaattaatcc tttggcataa
    22921 gtagccataa aattaacatt ttctgttgta gctgcttgtg cagaacaaat taagtctcct
    22981 tcattttctc tatccttgtc gtctataaca agaacaagtc gtcccttctg caatgcttct
    23041 aatgtttctt gtatttttcg atattccatt gactgattat cctttctgct aaaatccatt
    23101 ttgatataat agttccttag atatttctga ttttggagag ttatccatca gtttttgcac
    23161 atatttacct aagatatcat tttcaagatt tactgtactc ccgacttgtt tacttttaag
    23221 aatggtttgt ttcaaggtat gagggataac agatactgaa aagtttactt tggagacttt
    23281 agcgacagtc agactaatgc cgtcaattgt aatagatcct ttttcaacta ttaaatctaa
    23341 aatttctttt tgtgtgttga tttgatacca tacagcatta tcatcttttt ttattgacga
    23401 gatttttcct gtaccatcaa tgtgtcctgt aacgacgtga cccccaagtc gaccgttgat
    23461 agataaggct ctttctagat tcacctcact tccatgtttt aatagagtaa gagctgttcg
    23521 actccatgtt tcattcatta catcaactgt aaaggattga tgattgaaat gagtaactgt
    23581 aagacagata ccatttactg ctatactatc gcctaaatgg atatccgtta atatttttga
    23641 ggctttaatt gatagtttac aattacgaga gtctttctgt attctttcaa cttttccgat
    23701 ttcttcaatt attcctgtga acatggataa atcacttcac tttctatgag atagtcattt
    23761 cctatttgag aaaaagcata aggtttcaat ctaatagcgt catttggcaa agaaatgcct
    23821 tcacctccga caggaaactt ggcactgcct ccaaaaattt ttggtgcaat atatattttc
    23881 agctcatcaa caatttgttg ttccaaagca ctccaattca ttagactgcc cccttctaga
    23941 actaggctat caatctgcat gtttcctaga tgttgcatta aactcgataa gtctatatga
    24001 ttgccttttt tctttatgga aagtatttca cagccatgat tttgatatag cttcatttta
    24061 tttttgtctt cagaggaagt ggcaatgtaa gttttaatat catttgctgt ttttacgatt
    24121 ttagaggtaa gaggagttcg taaatgtgta tcgcatatga tacggatagg atttttccct
    24181 tcctccaatc tacatgtcag caaaggatcg tcttgaataa cagtattgac tcccaccata
    24241 attgcactaa catggtgtcg taactgatgc acatgctttc ttgcttcttc ttcagtaatc
    24301 catttggatt gatttgtttt agtggctatt tttccatcca ttgacattgc atatttcata
    24361 aaaacatagg gtacatgctg ggtaatatac tttctaaaac tttttattaa gttaagacac
    24421 tcattttcta aaattccaac agtaacttga agattatttt cctcaagtat ctttactcct
    24481 tttccagata caataggatt acagtctagg cttccaatga ctactcttgt aataccacta
    24541 tcgattatag catctataca gggaggtgtt ttcccgaagt gacaacaggg ttcaagtgtt
    24601 acataaagcg tcgctccgac aggggattct ctacagtttt taagagcatt tctctcagca
    24661 tgtgggccac caaaaaactc atgataacct tgtccgatga tgtgattatc ttttacaata
    24721 actgcgccga ccataggatt gggattgacg taaccagccc ctttttgtgc cagttttatt
    24781 gctaatttca tatattttga atcgctcatc tcactacctc caaaaaaaat ataccttgaa
    24841 taggggacta ctcaaggcat acaaaagaaa acttatgcga ttaacaaaaa tactctgaaa
    24901 tgacaagtaa tcatttcaga gcacgcaaaa agcacaaata tacttttatc ttctttcatc
    24961 cagactatac tgtcggcttt ggaatttcac caaatcatgc ctttcggctc gtgggctata
    25021 ccaccggtag ggaattacac cctgccctga agatagttat tcaattacag atgattatag
    25081 tacttaattt tgaatatgtc aacagataaa taccgattgt ttttgatata ctgtatttgt
    25141 gataatcgat tctcgctcct cggataaaga aaatatgata tactagataa acgaaataag
    25201 agagaaggaa tactatgtac gcatatttaa aaggaatcat taccaaaatt actgccaaat
    25261 acattgttct tgaaaccaat ggtattggtt atatcctgca tgtggccaat ccttatgcct
    25321 attcaggtca ggttaatcag gaggatcaga tttatgtgca tcaggttgtg cgtgaggacg
    25381 cccatttgct ttatggattt cgctcagagg atgagaaaaa gctctttctt agtctgattt
    25441 cggtctctgg gattggtcct gtatcagctc ttgctattat cgctgctgat gacaatgctg
    25501 gcttggttca agccattgaa accaagaaca tcacctactt gaccaagttc cctaaaattg
    25561 gcaagaaaac agcccagcag atggtgctgg acttggaagg caaggtagta gttgcaggag
    25621 atgaccttcc tgccaaggtc gcagtgcaag caagtgctga aaaccaagaa ttggaagaag
    25681 ctatggaagc catgttggct ctgggctaca aggcaacaga gctcaagaaa atcaagaaat
    25741 tctttgaagg aacgacagat acagctgaga actatatcaa gtcggccctt aaaatgttgg
    25801 tcaaatagga gcagagaatg acaaaacgtt gttcgtgggt caagatgaca aacccgctct
    25861 acatcgccta tcatgatgag gagtggggtc agcccctcca tgatgaccaa gcattgtttg
    25921 agttgttgtg tatggaaacc tatcaggcag gcctgtcttg ggaaacggta ctcaacaaac
    25981 gccaagcttt ccgagaagcc tttcatagct atcaaattca ctcagtcgca gagatgactg
    26041 agactgaatt ggaagccatg ctggagaatc cagctatcat tcgaaataga gccaagcttt
    26101 ttgctacacg cgctaacgcc caagtccttc tacagttaca ggcagagtac ggctcttttg
    26161 atgcctatct ttggtctttt gttgagggga aaattgtcgt taacgatgtt cctgattatc
    26221 gccaagcgcc agctaaaaca cccttatctg agaaattagc caaagatctc aaaaaacgag
    26281 gcttcaagtt cacaggccca gtcgccgtat tgtcttttct acaggctgca gggctagttg
    26341 atgaccacga gaatgattgt gagtggaaag gtcttaaatg atgtctaaca aaaataaggg
    26401 aattctgatt tttgcgattc tctatacagt cctctttgtg tttgatggcg ttaaattgct
    26461 ggcttcttta atgccatctg tcattgcaaa ttatcttgtt tatgtagttt tagctttata
    26521 tggctccttc ttgttcaagg atagattgat ccaacaatgg aaggagatta gaaagactaa
    26581 aagaaaattc ttctttggcg tcttaacagg atggctcttt ctcattctga tgactgttgt
    26641 ctttgaattt gtatcagaga tgttgaagca gtttgtggga ctagatggac aaggtctaaa
    26701 tcagtctaat attcaaagta cctttcaaga acaaccacta ctgatagctg tttttgcttg
    26761 tgtcattgga cctctggtag aagaattatt tttccgtcag gtcttattgc attacttgca
    26821 ggaacggttg ccaggtttac taagcattat tctggtagga cttgtttttg ctctgactca
    26881 tatgcacagt ttggctctat cagagtggat tggtgcagtt ggttacttag gtggaggcct
    26941 tgccttttct attatttatg tgaaagaaaa agagaatatc tactatcccc tacttgttca
    27001 catgttaagc aacagcctct ccttaatcat tttagctatc agtatagtaa aatgaaataa
    27061 gaacaggaca aatcgatcag gacagtcaaa tcgatttcta acaatgtttt agaagtagag
    27121 gtgtactatt ctagtttcaa tttgctgtaa tatgtgatga aaataccagt aatgataccg
    27181 agaaaaaagc tgagaaactt ttcccagctt tatttgttat agtcaaagcg aatgacttgt
    27241 tcctgtgcat ctacatgagc atggacccca aagggtacaa ttgctcttgg agttgcgtgg
    27301 ccgacattca gattatagac aatcgggata ttgctgtcaa tgatatccaa tagtgcctct
    27361 ttatagtcgt catggaaagt ttcatccata ggttttccga ccaagagtcc attgatgacc
    27421 gcgaatatgc cagtgtcctt taaagttagc aacatctttt tgaagtcttc tggcttaggc
    27481 ttttcttcgc ttgtttcgag caagaggatt ttcccttccc agtctgacaa gtcagggaaa
    27541 agtttgtatt tttggcagag ttccgtgcta tctgcgtatc gagagttgtc aaagatatcg
    27601 tagagggatt cgaggcaacc accgaggatt tttccctcga actgagcact tccttgcaac
    27661 aagtcaaaac ctgtatttgt atgactgaca cgaggtgttc ccagggccgt gggactaaaa
    27721 tcagttcgtt cctcatacca aacgtcacta gggcggattt ctgaaattct tcccgtctta
    27781 atcaattctt taaagtagtg aaggctatag gctagcattt ctttgtctaa ttcacaaatg
    27841 tctgctaaaa aggattgacc ataaaaagtc ttgattccta atttatgcaa catgaggtgg
    27901 ttcatggttg tatccgagaa gccaagaaaa attttttgct tgataacctt ttggagttgg
    27961 tcattttcaa aaagataagg tagcaagcga taggtatcgt ctccaccgat ggcacatagg
    28021 atcatgtcga tgctatcatc agaaaaggca tgaatcaaat cctctgcacg agcttcagga
    28081 tggtccttga taaagtctaa tccttttaac gaatgggaca aaaagatggg attgagtccc
    28141 agatccttga gacgttggat acccaagtcc acttcgtgtt tgacaaaatc ctctccgata
    28201 atgccactag ataaactaac aataccaata gtagaaacca tatctcatcc tcctagaaat
    28261 agattgagcc tattttatca caaaatataa gagaaagcta tgtgggattt cagaagaata
    28321 cttttaatac tcttcgaaaa tctcttcaaa ccacgtcagt tttatctgca acctcaaagc
    28381 tgtgctttga gcaacctgca gctagcttcc tagtttgctc tttgattttc attgaatata
    28441 actcaaaaaa gtaagtgaaa aagcaaccgc acctgcagtt gcttttatcg ttttcttatt
    28501 cttgatagcg tgttggtcct gcacttgcac tacggatatt caagcgtttc ttgagataga
    28561 agcgaagggc taggagggct gctccaataa tagctagtgg caatggatcc agtactgggt
    28621 taaggctagc tggtaggaag cttgttgcaa agaagacaag caaccaaagg aacatagaag
    28681 ctaggataac tagtacagat ttccagaaag gtggacgttg actgcgatcc atatctgatc
    28741 catagtattg gtaaacaaag tagtacatca agtagaaggc aaatccacca accagtccaa
    28801 ctaatagaag agtaatcaat ccatagccga aagcttggtc tgccgcaaag aaggttgtga
    28861 gggcgctgac aagggcaaag aggctagtga tgaaaagagc tgagtccata atcatcagtt
    28921 ttgggtcatc attttctttt ggatgctctt tttcgtactg ctctttgaca gtgaagctat
    28981 gagcccaatg agttggtgcg ccgtataggg aacgggcagt tgtaccttta gattgctcct
    29041 caaggatttg gggaatgact tcctcaaaaa tagtctggat ttcagcgtct gttttcccat
    29101 ctttgatgaa ttgttgggta gcaatgtgga caaactcttg gtttttctta gttaattttt
    29161 gtagatcaat ttgagacata ggaactcctc ttagaaccat tttttatgga tgagatagag
    29221 agtgagcgag acactcatag caaaggcgat aaagacgatt aaccagaagg catttggctc
    29281 tccgtttagg gggatttcat tatccttaaa gttcatcccg taggcagaaa agaccatggt
    29341 tgggatggac atgacgatgg tcacaagggc caaggttttc atgatgttgt tctggttgtt
    29401 agaaatgata gaggcaaagg tctctgtcat agaatgcaag acgtttccat aaatatctgc
    29461 catctcgatg gcctgttggg tttcaatcag ggtgtcttca agcaggtctt cgtcctcaag
    29521 gtatttcttg atattgctgg ttgaactggt caatttctta atcacgcgct catttgtttt
    29581 gagggaggcc ttgaaataga cgatagtttt ttccaattcc atgagctcaa tcaattcttc
    29641 attacgagtt gattgatgca gttgactttc gatttgttca ctcttgcggt cgattgaacg
    29701 aagggctgtt aggtaaagct ctgcattgcg ataaagaatt tgaaagataa aacgtgaacg
    29761 catgaaggta tagaaattac gcaatcgacg gttgataaag acatcaagga caggtagtgg
    29821 ttccaaacac gtagtgataa tggtttcctc agtgatgata ataccaagcg ggatggttac
    29881 gtagtaggtg cggttatttc tttcctccgt gaccggcacg tctacgataa tcagggtata
    29941 ctcgtcttca atggtaatac gagacatttc ttccgcatcg agcggtgctc gaaggtcggc
    30001 aatatcaata tcgaaggtgt tggcgatttc gagtgattca ttttgagtcg gattgacgag
    30061 attgatccaa gtacccggtt caagcgtatc gatctcttta aattcagttg ttgtagagag
    30121 aaaaacttgt ttcatatccc ttatcctttc tcatttttca gattttttca cactgtacta
    30181 ttatactaca aaatcggcct tttgggtaat agaatctcac tttttttggt ataatggtaa
    30241 gcaataatgg actagaaaga acaaagatgc aagataaaat tgtcattcat ggggcgcgtg
    30301 cccataattt aaaaaatatt gatgtggaga ttccgcgaga caagttggtt gtcgtgactg
    30361 gcttgtcagg ttcagggaag tccagtctgg cttttgatac tctctatgcg gagggacaac
    30421 gtcgctatgt agagagtttg tctgcctacg ctcgtcagtt cttgggaaat atggaaaaac
    30481 cagatgtaga tgccattgat ggtctcagcc cagctatttc catcgaccag aaaacgacta
    30541 gtaaaaatcc tcgctcgacg gtgggaacga cgactgaaat caatgactat ctgcgtctcc
    30601 tctacgcacg tgtggggacg ccttactgta tcaacggaca tggagctatc aatgcttctt
    30661 ctgtggagca aatcgttgat aaggttttgg agttacctga acgccagcgc ttgcagatct
    30721 tggctcctgt catccgcaag aaaaaaggcc aacataagag tgttatcgag aaggttcaga
    30781 aagacgggta tgttcgtgtt cgtgtggatg gggaagtcta tgatgtgacc gaagtgccag
    30841 agttgtctaa gagcaagcaa cacaatatcg atgtcgtggt tgaccgtatt gttatcaagg
    30901 agggcattcg tagccgtctc tttgattcca ttgaagctgc ccttcgtatc gcagaaggtt
    30961 atgtgattat cgacaccatg gacgactctg agttgttgtt ctctgagcat tatgcctgtc
    31021 cagtttgtgg atttactgtc ccagagttag aacctcgtct cttctctttc aatgctccct
    31081 ttggctcttg tagtgagtgt gacggcttgg ggattaagct ggaggtggat actgatttgg
    31141 tagtgccaga tgccagcaaa accttacatg agggagcgct ggcaccttgg aatcctatct
    31201 catccaacta ctatccaaac atgttagagc aggccatgaa agtctttgga gtggctatgg
    31261 ataagccttt tgaggacctg tcagaagaag ataagaactt gattctctac ggctcagatg
    31321 gtaaggaatt ccatttccat tatgaaaatg aatttggtgg tgtgcgcgat atcgacattc
    31381 cgtttgaggg agttatcaat aatatcaaac gtcgttacca tgaaaccaat agcgattaca
    31441 ctcgcactca gatgcgtctc tacatgaatg agctgacctg cggaacctgt caaggctatc
    31501 gtctcaatga ccaggccttg tctgtccgtg tgggcggcca gcaagggcca catattggag
    31561 aaatctcaga cctgtctatc gctgaccact tggacttggt gagccagtta actttgtctg
    31621 aaaatgaagc catcattgct cgtcccattc tcaaggaaat caaggatcgt ttgaccttcc
    31681 ttaataatgt gggtcttaac tatctaaccc tgtcacgttc agcaggaacc ctttcaggtg
    31741 gggaaagtca gcgcattcgt ttggcaaccc agattggttc caacctatca ggtgtcctct
    31801 atatcctaga cgagccgtca atcggtcttc accagaggga caatgaccgc ctgattgcca
    31861 gtctgaaaaa gatgcgtgac ttgggcaata ctcttatcgt ggtggaacac gacgaagata
    31921 ccatgcgtga agctgattat ctgattgacg ttggtcctgg tgccggtgtt tttggtggtg
    31981 agattgttgc agcaggtaca cctaagcaag tggctcgcaa cagcaagtct atcacaggtc
    32041 agtacttgtc aggcaaacgt gtcatcccag taccagaaga gcgccgtgtc ggaaatggtc
    32101 gttttattga agtgacagga gcgcgtgaga acaacttgca aaatgtcacg gctcgctttc
    32161 cactaggaaa atttatcgca gtgacaggtg tgtcgggttc agggaaatcg actctaatca
    32221 acagcattct caaaaaagcc attgcccaga agctcaaccg taattcagac aaacctggta
    32281 agtttaagac tattacaggg attgagcatg tcgaccgttt gattgatatt gaccagagcc
    32341 ctatcggacg gacgccgagg tctaacccag ctacctatac aggagttttt gacgatatac
    32401 gtgacctttt tgctcagaca aatgaagcca agattcgagg ctacaagaag gggcgcttca
    32461 gtttcaacgt caagggaggt cgctgtgaag cttgctcagg tgacgggatt atcaagattg
    32521 agatgcactt cttgccagat gtttatgtgg cttgtgaagt ttgccacgga acccgctata
    32581 acagtgaaac cctagaagtt cactacaagg aaaagaatat ttcgcaggtc ttggatatga
    32641 cggtcaacga tgcggtagaa tttttccaac acattccgaa aattcaacgc aaactccaga
    32701 ccatcaagga tgtaggtcta ggctatgtga ccttgggaca gccagctacc accctttctg
    32761 ggggagaagc ccaacgtatg aagttagcta gcgaactcca caaacgctcg acaggaaaat
    32821 ctttctacat tctggatgag ccgacgacag ggcttcatac agaggacatt gctcgcctgc
    32881 tcaaggtttt agctcgcttt gtagacgccg gcaatacagt cctcgtcatc gagcacaatc
    32941 tggatgttat caagacggca gaccatatca ttgacttggg acctgagggc ggtgtcggtg
    33001 gtggaaccat catcgtaaca ggaactccag aagaagtagc tgccaacgaa gccagctata
    33061 caggacacta tttgaaagga aagttacatc atgaataaac gcgtacaagc atttctagct
    33121 aaaatgcaag aaaaagaact agatggtatc atcatcaaca atcttaaaaa cgtctattat
    33181 ttgactggtt tttggggctc aaacggaaca gtctttatca gccgtgaccg tcaggtctta
    33241 gtgacagact ctcgctatat catcgcagct aagcaagaaa ccagtggttt tgagattgtg
    33301 gctgatcgtg atgaattggc tgtcattgca ggaattgtta aggacatgaa cttgactcgt
    33361 atcggttttg aagatgagat ttcagtgtct tattaccacc gtatgcaggc agcttttgca
    33421 ggtttgaact tgcttccaca aactcagttt gtggaaggtc ttcgtatgat taaggatgag
    33481 gcagagattg cagcgattcg caaggcttgt tctatctcag accaagcttt ccgcgatgcg
    33541 cttgacttta tcaaaccagg aaaaactgaa attgagattg ccaacttcct tgatttccgc
    33601 atgcgtgagt tgggagcatc tggcttatct tttgatacga tcctagctag cggtatcaat
    33661 tcttctaaac cccatgccca tccaatgcac aaaccagtgg agttgggaga agccattacc
    33721 atggacttcg gctgtctcta tgaccactat gtcagtgata tgacccggac tatctatcta
    33781 gggcatgtta gcgatgagca ggcagagatt tacaatacgg ttctaaaagc taaccaagcc
    33841 ttgattgacc aagctaaggc aggcttaggt ttccgtgact ttgacaaaat ccctcgtgat
    33901 attatcattg aggcaggtta tggtgactac tttactcacg gcattggcca cggtattggt
    33961 ctggatatcc atgaggaacc ctactttagt cagacttcta cagaaactat taagacaggt
    34021 atggccttga ccgatgaacc aggtatctat atcgaaggca aatatggcgt tcgtatcgag
    34081 gatgatatcc tgattacaga gacaggttgt gaattattga ccctagctcc aaaagagttg
    34141 atagtcattt agttgtttgt caagaaaaaa gtacgaaaat gacgaaaaaa gtcaaaaaaa
    34201 attaaaaata ggtcgcaagt cggatgtttt ttatggtata atagactaaa ctgatagtaa
    34261 catgtagcga aaggggtagg tacatgatta aaatttatac agtctcaagt tgtactagtt
    34321 gtaaaaaagc aaaaacctgg ctcaatgccc accagttaag ttataaagaa caaaaccttg
    34381 gtaaagaagg aattacgaga gaagaattac tggatattct aaccaaaaca gataacggaa
    34441 tagccagcat cgtttcgtct aaaaatcgct atgccaaagc ccttggagtg gatattgaag
    34501 atttgagtgt caatgaagtt ctcaatctga ttatggaaac accgagaatt ttaaagagcc
    34561 caatccttgt agatgaaaaa cgcctgcaag ttggctacaa ggaagacgat attcgtgcct
    34621 tcctaccacg ctctgtccgt aatgtagaaa atgcagaagc acgtttgcgt gcagctctat
    34681 aaacatcaag gctgggagca cttcccagtc ttattctatt ttaatttcaa aaagaaagaa
    34741 gaaagaaatg aaaaaaatag ttcttgttag tctagctttc ctttttgtcc tggttggttg
    34801 cggacagaaa aaagaaactg gaccagctac aaaaacagaa aaagatacgc ttcagtcggc
    34861 attgccagtt attgaaaatg ctgagaagaa tacagttgta actaagactt tggtcttgcc
    34921 caagtcagat gatggtagcc agcagacaca aacaattact tacaaagaca agactttttt
    34981 gagtctagct atccaacaaa aacgtccagt ctctgatgag ttgaagactt atattgacca
    35041 acatggagtg gaggaaactc aaaaagctct tcttgaagcg gaggagaagg ataagtctat
    35101 cattgaagct cgtaaattgg caggtttcaa acttgaaaca aaactattga gcgcaacgga
    35161 acttcaaaca acgactagtt ttgattttca agttctggat gtcaagaagg cttcccagtt
    35221 ggaacatctg aagaatattg gtttggaaaa tcttttgaaa aatgaaccaa gcaaatatat
    35281 ttcagataga ttggcaaatg gcgcgacaga acaatagaaa atccaaataa atagactgcc
    35341 tgaattgtag aaggtaagga attatgctat aatggtacta ttctaaggaa agagggtgtt
    35401 agaatgggat ttactgaaga aacagtacgt tttaaattgg acgattccaa taaaaaagaa
    35461 attagcgaaa ctttgacaga tgtttatgct tcgttgaacg ataagggtta caacccaatt
    35521 aaccaaatcg taggttacgt attgagtgga gaccctgcct acgttcctcg ttataataat
    35581 gcacgaaatc aaatccgtaa gtatgagcgt gatgaaatcg ttgaggaatt ggttcgctac
    35641 tacctcaaag gacaaggagt cgatctataa cctatgagaa ttatgggatt ggacgtcggt
    35701 tcaaaaacgg taggggtggc gattagcgat ccgcttggtt ttacagctca agggcttgaa
    35761 atcatccaga taaatgaaga acaaggccaa tttggttttg accgcgttaa ggaattggtt
    35821 gatacttaca aggtggaacg atttgtagtg ggcttgccta aaaacatgaa caatacaagt
    35881 ggaccgcgcg tagaagctag tcaagcctac ggagcaaagc tagaagagtt ttttggttta
    35941 ccagtagact atcaggatga acgcttgaca acagtggctg ctgagcgcat gttgattgaa
    36001 caagcagata tcagtcgcaa taagcgcaag aaagtcattg ataagttagc agctcagctg
    36061 attttacaaa attatttaga tagaaaattt taatataaag gagaggctat gtcacacgat
    36121 cataaccacg accacgaaga acgtgaacta atcacactag tagatgagca aggaaatgaa
    36181 accttgtttg aaatcctttt gacaattgat ggaaaagaag aatttggtaa aaactatgtt
    36241 cttctagtac cagttaacgc agaagaagac gaagacggac aagttgaaat ccaagcttac
    36301 tcattcattg aaaatgaaga tggaacagaa ggcgaattgc aaccaatccc agaagactca
    36361 gaagacgaat ggaacatgat tgaagaagtc ttcaacagct ttatggagga gtgatacagt
    36421 ctgggagact gtatcagccc aactccagaa atggggaaga gttggaacgt ccagtgaaca
    36481 tttttacccc aactcttaga aattgagaag agttggaaca tctagtggat gtttttagcc
    36541 catattcaca ttcatagtag ctagttatta gctaaccagg taagaggtcg ggacgaaaat
    36601 cctggccttg tttttattag taaccatact ttaatgcgat aattgattgg acttttgtca
    36661 aggagatgtg tatgtttgaa gtagaagaat ggctccatag tcggattggt ttgaattttc
    36721 gatcaggttt gggccgaatg cagcaagcgg tggatttgtt aggaaatcct gagcagtctt
    36781 accctattat ccacgtaaca gggactaatg ggaaaggatc taccattgct tttatgaggg
    36841 aattatttat ggggcatggc aaaaaagttg cgacctttac ctcccctcat atcgtctcta
    36901 tcaatgaccg aatctgcatt aatgggcaac ctatagcaga cgcagacttt atccgtttga
    36961 ctgatcaggt caaggagatg gagaaaacgc ttctgcaaac tcctgcccag ttgtcctttt
    37021 ttgaattgct gaccttagtt gcttttcttt attttaggga gcaagaggtg gatttggttt
    37081 tattagaagt gggaattggt ggcttacttg acacgaccaa tgtggtaact ggagagcttg
    37141 ctgtcatcac ctccattggg cttgaccatc aagaaacctt gggtgatagt ctagaagcaa
    37201 ttgcagagca gaaagctggt attttcaagg ctggtaaaaa ggcagtgatt gcgaaattgc
    37261 ctccagaagc tagacttgtc tgtcagaaaa aagccgaatc tttagctgtt gacctttatc
    37321 aggcaggtca agatttttca gtgctgaatg gtgatttttc aagctcttta ctaaatcttt
    37381 cacagctgaa cataggctta gaaggagcct atcagcagga gaatgcggcc ttggcgttgc
    37441 aaacttttct tctttttatg ggagaaagaa aggaagctat tgatgaacag gctgtaagaa
    37501 aggccttgga acagacccat tgggctggtc gcttggagcg tattcgccca cagatttact
    37561 tggatggtgc tcataacctc cctgccttga ctcgcttggt tgagtttatc aaagaaaaag
    37621 agcaggaagg ctatcgacct caaatcctct ttggatcctt gaaacgtaag gattatcaag
    37681 ggatgttggg ttatctgact gaaaatttac ctcaagtgga actcaaaatg accggctttg
    37741 actatcaagg gtctttggac gagacagatg taacaggtta ccatgtaatt ccctcttacc
    37801 gagaatttat cagcagtttc gaagaaaggg cagacgctca agacttgctg ttcgttacag
    37861 ggtctctcta ttttatctca gaagtacggg gctacctgct ggaccgtgag cagataaatt
    37921 gacccccttt tttgaacttg ttatactagg ggaattgctg gttagagaaa atttctctaa
    37981 attggtagca gaaaggaaat tcatcatgaa attaaaaaga ttcacacttt ctcttgcttc
    38041 tctagcaagt tttagtctct tagtagcttg ttcacaaaga gctcaacagg ttcaacagcc
    38101 tgttgctcag caggtccaac agcctgctca acagaatacc aatactgcaa atgcaggagg
    38161 taaccaaaat caagcggctc cagtacaaaa ccaacctgtt gctcaaccga ccgatattga
    38221 tgggacttat actggtcagg atgacggaga ccgtatcact ttagtggtaa ctggaacgac
    38281 tggtacatgg actgagctcg aatctgacgg ggatcagaaa gtcaaacagg ttacatttga
    38341 ttcagcaaat caacgcatga ttattggcga tgatgtcaaa atttacactg taaacggtaa
    38401 tcaaatcgtc gtagatgata tggatagaga cccatcggac caaatcgttt taactaaata
    38461 agactatgca agtagaaagg gctggatttt tcagcctttt tacttttacc tagaaaataa
    38521 tcataaatac ttgccttcta ccgaatacct gcgttatact agtatcaatt acttgttttt
    38581 agcattcaaa ctatcaagga ggggatatga aatataggaa atttcaatta ttgatgtcca
    38641 agtatggctt tagtctttcg attatgctac ttgaactttg tcttgttttt ggtctctttc
    38701 tttatttagg acgcatggct cccattttat ggattactgt cctcattcta ctgagtatca
    38761 tcacaatcat ttcgatagtc aaccgtaata cgactcctga gaataaggta acctggttgt
    38821 tagtagcctt tgtgccagta tttggtccct tgctctatct gatgtttggt gaaaggcgat
    38881 tgtccaaaaa agaaatcaaa caactgaaga agctaggctc tatgcatttc caagaagcaa
    38941 atagccagct actaaaagag aaattaaaag aaagtgacaa ggcagcttat ggagtcatca
    39001 agtccttatt gagtatggat accaatgctg acatctatga tcaaactgcc tctacatttt
    39061 ttcctaacgg agaagctatg tggaaaaaga tggtagaaga tcttaaaaag gctgagaaat
    39121 ttattttctt ggaatattac attatagaag aaggtttgat gtggaatcgc atactagata
    39181 tactagagca aaaggtagct cagggtgtag aggttaagat gctctatgat gatatcggct
    39241 gtatggctac tttaacagga gattatgcac atcgacttcg tcagctgggc atcgaggccc
    39301 ataaattcaa taaagttatt cctcgtttga cagtggctta taataacaga gatcatagaa
    39361 aaatattgat tgttgatggt cagatagcct atactggtgg ggtcaatctg gcagatgagt
    39421 acattaacca cgtcgagaga tttggttatt ggaaggatag tggaattcgc ttagacggac
    39481 tagcagtaaa agccctgaca cgcttatttt tgaccacttg gtacattaat cgaggagaaa
    39541 ttagtgattt tgatcaatat catttagaaa atcattctat cccgagtgac ggtttaacca
    39601 ttccatacgg aagtggaccc aagccaattt ttcgagcgca ggtagggaaa aaagtttatc
    39661 agagtttaat caatcaagca acagaatcgg tctatattac gacaccttat ttgattatag
    39721 attatgattt aacagagaca atcaaaaatg cagctatgag aggggtcgat gttcgaatta
    39781 tcacccctta cataccagat aagaagttca ttcagttagt cacgagagga gcttatcccg
    39841 accttctttc tgctggtgtt cggatttatg agtatagtcc aggttttatt catagtaagc
    39901 agatgttggt agacgaagat tttgcggtgg tggggacaat caatctcgac taccggagct
    39961 tggtacacca ttatgaaaat gcagtcttac tctataaaac tccttctata agggaaatcg
    40021 cccgagattt tcgaaatata tttgcagatt ctcaggaagt ctatcctcat tctatcaaaa
    40081 cgagctggta tcaaaagctt gtaaaagaaa tcgcccagct attcgcccct atcttataag
    40141 aaatctagaa cttaggatac aaaccagacc tatttttctt gtcttttact aatagaaaga
    40201 aagaggaggg gaattcatgc taactaagga agaagtgaat gatatgattg agttcaaaca
    40261 gacacattta caccgctttc gggaaattga aacctttgtg aaactatgca aaaaatcact
    40321 caaacagcca tcgcaagctg acaatcctag gactttttga tatactaaga cagataaatt
    40381 gaacaggaga aacgatatga gtgtgtatgg tagagtagaa gaagttcata aggagaatcg
    40441 tgaacctcta gaataccaaa tcgaacaaga atcgcatcat cgtgaatcaa gtcgtcttcc
    40501 tttggtgaaa attttactat ggagtacgct tgtaacgggg ataactctag gagtaccgct
    40561 attactcgac ttaatgagtg cacaagaagt gcaggatttt tatgcaggtt gggggcttca
    40621 tcagacaggg aagatttaca gcgactatta tggaagtcaa ggtttgcttt attatttgct
    40681 gacttacgtg agtcagggcg gatttttctt tgccatcttt gagtggttag ccttggtagc
    40741 aggaggattt ttccttttta gatcagcgga caccttgaca gagcaaggag accaagctgg
    40801 acatctggtg actatttttt acatgctagt tacaggtctt gcttttggtg gaggctatgc
    40861 gactctttta gcgcttcctt tcttattcgc agcctttagt ttagttgcgg cttacctaag
    40921 caatccaagc catgataagg gatttgtacg gattgggcta gctttggcag gcggattttt
    40981 ctttgctccc ttatcatcgc tcctgtttat tgctgtagtg agtttaggct tgttggtctt
    41041 taaccttggg catagacgct ttgcgcatgg gttttatcag tttcttgcag tggctttagg
    41101 tttttcactt gtcttttatc caactgccta ctatagtgct gcaacaggaa gttttgggga
    41161 tgcgattagt ggtattcgtt atcctattga cagtattcgc tttgatttta cttctaaaat
    41221 tttagagaat atgttttttt atggcttgtt gtcccttggt ttgggatttg tggtttgtat
    41281 ctttttaggt ctctttcaat ccaaaccctt taaactatac gtcatttcgg ttcctgcaag
    41341 tcttgtggta attttaggtt tgattttact tttcttttca caagagcctc tgcacgcttc
    41401 ttatttgatg gtcgtcttcc ctgttttcct acttttattg gtaaccaata ttaagagtca
    41461 acagaggggg cgtagtgcta gaagaagccg aagagaaacg ccagttagcc tatggagtcg
    41521 tttcttcaaa ggaaatctat atctgctagt ttttgggttt gtctatcttt tgtctgttcc
    41581 ttttttgatg aagtttgtcc tttatccagt accttatcaa gaacgtaatc gtcttgctga
    41641 tttggtaaaa gaggagacaa atacggaaga tgctatctat gcatgggatg atactgcgac
    41701 tctttatcgt aagagtgagc gcttgtcgcc atcggcgatt ttgtccccgt tgcactatac
    41761 agcaactgag gaaaatcgta ataagttact taatgacttg aaagaaaaac aacctaaggt
    41821 gattgtggta aatgacaagg tggtagtctg gtctgaagtg gaaacacttt taaaagaaaa
    41881 ttaccaacaa gtaaagactg attactcaga gtttaaagtc tataaaatta aataaccaaa
    41941 tcaatatctt gtgtattttt aaaaatttta ggatttttaa cacaagatat tgatttttct
    42001 ttttagagtg gtataatact ttttagaaag aacattttag aaaagagcat gcgtatgatt
    42061 gcactagaag aaaaaattac aattttgcca actctcttcg tcgagaaacg agatgggaga
    42121 cgtgttgtat ttgatgtgga caagattgac aaggctctcc acaaggcggc tgacaaggtt
    42181 atggatgtga cacccctggt tgaaaaacgc ctcaatgatc tgactgagcg aattattaca
    42241 gaaattcata gtcgctttcc acagggaatt aagatttacg aaattcaaaa tatcgtagaa
    42301 catgaactcc ttgaagccaa agaatatgcg ctggctgagg agtatattac ttatcggaca
    42361 cagagggatt ttgagcgctc aaaagcgacg gatatcaact ttagtattca taaacttctc
    42421 aacaaagacc agacagttgt caatgaaaat gctaataaag acagtgatgt ctttaacact
    42481 cagcgtgatt tgacagcagg gattgttggg aaatcaatcg gactgcaaat gcttcctaag
    42541 cacgtagcca atgcccacca aaagggggat atccactatc acgatttgga ctacagtccc
    42601 tataccccta tgaccaactg ctgtttgatt gattttaagg gtatgttgga aaatggtttt
    42661 aagattggaa atgcagaggt agagagtccc aagtctatcc agactgcgac agcacagatt
    42721 tctcaaatca ttgccaacgt tgcttctagc cagtacggtg gctgttcagc tgaccgtatc
    42781 gatgaaattt tggcgcctta tgcagagaag aattatcaaa aacatctcaa agatgcagaa
    42841 gagtgggtat tgcctgaaaa acgggaagat tacgcttgga agaaaacgca aaaggacatc
    42901 tacgatgcca tgcaatctct tgagtatgaa atcaatactc tcttcacttc aaatggacaa
    42961 acacctttta cttcgttagg ttttggtctg ggaaccagtc gttttgaacg agaaattcaa
    43021 aaagctattt taaacattcg catcaagggt cttggttcag aacaccgtac ggctatcttt
    43081 cctaaactta ttttcactct gaaaagaggc cttaatttag aggaaggaac tcccaactac
    43141 gacatcaagc agttggctct tgagtgtgca accaaacgga tgtatccaga tgttttatct
    43201 tacgataaga ttgttgactt gacaggatcc ttcaaggtgc ctatgggttg ccgttctttc
    43261 ctccaaggat ggaaggatga aaatggtgta gaagtcaatt caggtcgcat gaatctgggt
    43321 gttgtgacgg ttaatctgcc tcgtattgct cttgagtctg aaggtgatat gaataagttc
    43381 tgggaaatct tcaacgagcg aatgaatatc gcagaagatg ctcttgttta ccgtgtcgaa
    43441 cgcactaaag aggcgacacc agcaaatgct cctattcttt atcagtacgg tgcttttggc
    43501 catcgtctag gtaaagaaga aagtgttgac cagctcttta agaatcgtcg tgctaccgtt
    43561 tcgctgggct atatcggctt gtatgaagta gcgacagttt tctttggtaa cagctgggaa
    43621 agtaatccag atgctaagga attcacgcta gacatcattc acgatatgaa acgccgtgta
    43681 gaagagtggt cagaccaata tggctaccat ttctctatct actcaacacc atccgaaagt
    43741 ctgacagacc gtttctgtcg actagatata gacaagtttg gctctattcc tgatatcaca
    43801 gacaaggaat actacaccaa ctctttccac tacgatgttc gtaaaaatcc aacaccgttt
    43861 gaaaaattgg actttgagaa agtctatcca gaagcaggtg cgtcaggtgg tttcatccat
    43921 tattgtgagt atccagtcct tcagcaaaat ccaaaggcct tggaagctgt ctgggattat
    43981 gcttatgacc gtgtaggcta tctaggcacc aatactccga ttgaccgttg ctacaagtgt
    44041 gactttgaag gggattttga accaactgag agagggtttg cttgtccaaa ctgtggcaat
    44101 agcgacccta aaacagtaga tgtggtgaag cgaacttgtg gctacctagg taatcctcaa
    44161 gcaagaccga tggtcaacgg ccgtcacaag gaaatcgctg cgcgtgtcaa acatatgaat
    44221 ggttcaacga ttaaaatagc tgggcatcaa gtaacaaatt agaaagaaat gaaatgggaa
    44281 aatatcaact agacgataag gggcgcgcac aagtgacccg ttatcacgag aaacactcta
    44341 aaggtggagc tggtaagaaa gaacgcttgc ttagcttcag agaacaattt ttaaacaaga
    44401 acaagaaaaa ataaaagtga gagccagctc tcgcttttct catagtggga ggtaaggatg
    44461 gaattacgca gaccaagatt agcggataag aaagctgttt tagatatgat gacagagttt
    44521 gaaaagagcc aatcagccca tgatggagga ttttgggata cagagaattt tgtgtatgaa
    44581 gagtggttgg aaagcaatca ggaacaggaa atggggatta atctgcctga aggatgggtt
    44641 cctgcaattc agttagtggc tttttctgag aaaggtcaag cagttggatt tcttaatctc
    44701 cggttgcgcc tcagtaactt tttactagaa gaaggtgggc acattggcta ctccatccgt
    44761 ccatctgaaa gaggcaaggg ttatgcaaaa gagactctcc gtcagggctt gcaagttgct
    44821 aaggaaaaga acatcaagaa agctctggtg acctgtagcg tgaataatcc tgctagcaga
    44881 gcagtcattc tagcaaatgg tggaatattt gaggatgctc acaatggagt cgagcgttat
    44941 tggatagagg tagcgaatga ataatccaaa accacaagaa tggaaaagcg aggaacttag
    45001 tcaaggtcgt atcattgact acaaggcctt taactttgtg gacggcgaag gcgtgcgtaa
    45061 ctctctctat gtatcaggct gtatgtttca ctgcgaggga tgttataatg ttgcgacttg
    45121 gtcttttaat gctggcattc cctatacagc agaattagaa gagcagatca tggcagatct
    45181 tgctcagccc tatgttcaag gtttgacttt gttgggaggg gagccttttc ttaatactgg
    45241 gattctcttg ccacttgtta agcggattcg gaaggaattg ccagacaagg acatctggtc
    45301 ctggaccggc tacacttggg aagaaatgat gttggaaact ccagataaac tggaattctt
    45361 gtcactgatt gacattcttg tcgatggaag atatgatcga actaagagaa atcttatgct
    45421 ccagtttcga ggttcatcta accaacgaat tatcgatgtg caaaaatcgc tcaaaagtgg
    45481 gcaagtagtg atttgggaca agctcaatga cggaaaagaa agctatgaac aggtgaagag
    45541 agaatgaaga aaaaagactt agtagaccaa ctagtctcag agatcgagac ggggaaagtc
    45601 aggacactgg gaatatacgg tcatggagct tcaggtaaat caacctttgc acaggaattg
    45661 taccaagctt tagattctac tacagtaaat ttgctagaaa cagatcccta tatcacctcc
    45721 ggacgctatt tggtagtacc caaggacgcg ccgaatcaaa aggtgacagc cagtctgcca
    45781 gtggcgcatg aactggagag tttgcagaga gatatccttg ccttgcaggc gggtatggat
    45841 gtcttgacaa ttgaagaacc ttggaaggct agtgaggtct tgtctggagc caaaccaatt
    45901 ttgattgtcg aagggatgtc tgttggtttt ctacccaagg aactctttga aaaaaccatc
    45961 tgtttctaca cggatgagga gaccgaatta aagcgacgcc ttgctagaga tacgactgtg
    46021 agaaatcgcg atgcatcctt tatattggct agccatcaga tgagacggga gcagtatctg
    46081 cgatactata aagaaactga gtctaaggcg gatatcttag tggaccaatc agaagataaa
    46141 tttgatgtca agaggactta acttatgtat agaagaaata tagaagaaaa tccctaattt
    46201 tagaaagaaa aagtaggaaa acagtttcat cccaaaaaaa cgaaaaaacc taacaaatcc
    46261 cttgcaatcg caggggattt gtgttattct attatggtgc tgtaaattac agccttagtt
    46321 ttgatgcaag aggttgcgac acgctcggtt gcattgccac gcaacaccgc gtcggttttc
    46381 ttgtggagct agcctattat cttaaataga cgaaaaggag aaaaagatgg caaacaaaaa
    46441 aatccgtatc cgtttgaaag cttacgaaca ccgtacgctt gacacagcgg ctgcaaaaat
    46501 cgtagaatca gctactcgta caggtgcaca agttgcgggt ccaatcccac ttccaactga
    46561 acgtagcctc tacacaatca ttcgtgcgac tcacaaatac aaagactctc gcgaacaatt
    46621 tgaaatgcgt acacacaaac gtttgatcga tatcgttaac ccaactcaaa aaacagttga
    46681 tgccttgatg aaattggatc ttccaagtgg tgtaaacgta gaaatcaaac tttaatctaa
    46741 aatataaaag agcagaggct ggtgtttcaa tctaattgaa cacgggctag actcggtgtg
    46801 aaaaagataa acttcctatt gtccgctaga cactgcgtta gtttcctatt ttcactttga
    46861 gtttgacgcc ctttgtatct tagacttgag cataaaaaac gctcgttaaa aactttttga
    46921 ataaaaaata tagaaaagga actattttct catgacaaaa ggaatcttag ggaaaaaagt
    46981 gggaatgact caaatcttca ctgaagctgg cgaattgatc cctgtaacag ttattgaagc
    47041 aactccaaac gttgttcttc aagttaaaac tgttgaaaca gacggataca acgctatcca
    47101 agttggtttc gatgacaaac gcgaagtatt gagcaacaaa cctgctaaag gacatgtagc
    47161 gaaagctaac acggctccta agcgcttcat tcgtgaattc aaaaacgttg aaggcttgga
    47221 agttggtgct gaaattacag ttgaaacatt cgcagctgga gatgttgttg atgtaactgg
    47281 tacttctaaa ggtaaaggtt tccaaggtgt tatcaagcgc cacggacaat cacgtggacc
    47341 gatggctcac ggttctcgtt accaccgtcg tccaggttct atgggacctg ttgcacctaa
    47401 ccgcgtattc aaaggtaaaa accttgcagg acgtatgggt ggtgaccgcg taacaattca
    47461 aaatcttgaa gttgtacaag ttgttccaga aaagaacgtt atccttatca aaggtaacgt
    47521 accaggtgct aagaaatctc ttatcactat caaatcagca gttaaagctg gtaaataata
    47581 aagaaagggg aaatcagtca caatggcaaa cgtaacatta tttgaccaaa ctggtaaaga
    47641 agctggccaa gttgttctta acgatgcagt atttggtatc gaaccaaatg aatcagttgt
    47701 gtttgatgta atcatcagcc aacgcgcaag ccttcgtcaa ggaacacacg ctgttaaaaa
    47761 ccgctctgca gtatcaggtg gtggacgcaa accgtggcgt caaaaaggaa ctggacgtgc
    47821 tcgtcaaggt tctatccgct caccacaatg gcgtggtggt ggtgttgtct tcggaccaac
    47881 tccacgttca tacggctaca aacttccaca aaaagttcgt cgcctagctc ttaaatcagt
    47941 ttactctgaa aaagttgctg aaaacaaatt cgtagctgta gacgctcttt catttacagc
    48001 tccaaaaact gctgaatttg caaaagttct tgcagcattg agcatcgatt ctaaagttct
    48061 tgttatcctt gaagaaggaa atgaattcgc agctctttca gctcgtaacc ttccaaacgt
    48121 gaaagttgca actgctacaa ctgcaagtgt tcttgacatc gcaaatagcg acaaacttct
    48181 tgtcacacaa gcagctatct ctaaaatcga ggaggttctt gcataatgaa tttgtatgat
    48241 gttatcaaaa aacctgtcat cactgaaagc tcaatggctc aacttgaagc agggaaatat
    48301 gtatttgaag ttgacactcg tgcacacaaa cttttgatca agcaagctgt tgaagctgct
    48361 ttcgaaggtg ttaaagttgc caatgttaac acaatcaacg taaaaccaaa agctaaacgt
    48421 gttggacgtt acactggttt tactaacaaa actaaaaaag ctatcatcac acttacagct
    48481 gattctaaag caatcgagtt gtttgctgct gaagctgaat aatctaagga ggaaatatcg
    48541 tgggaattcg tgtttataaa ccaacaacaa acggtcgccg taatatgact tctttggatt
    48601 tcgctgaaat cacaacaagc actcctgaaa aatcattgct tgttgcattg aagagcaagg
    48661 ctggtcgtaa caacaacggt cgtatcacag ttcgtcacca aggtggtgga cacaaacgtt
    48721 tctaccgttt ggttgacttc aaacgtaata aagacaacgt tgaagcagtt gttaaaacaa
    48781 tcgagtacga tccaaaccgt tctgcaaaca tcgctcttgt acactacact gacggtgtga
    48841 aagcatacat catcgctcca aaaggtcttg aagtaggtca acgtatcgtt tcaggtccag
    48901 aagcagatat caaagtcgga aacgctcttc cacttgctaa catcccagtt ggtactttga
    48961 ttcacaacat cgagttgaaa ccaggtcgtg gtggtgaatt ggtacgtgct gctggtgcat
    49021 ctgctcaagt attgggttct gaaggtaaat acgttcttgt tcgtcttcaa tcaggtgaag
    49081 ttcgtatgat tcttggaact tgccgtgcta cagttggtgt tgtcggaaac gaacaacatg
    49141 gacttgtaaa ccttggtaaa gcaggacgta gccgttggaa aggtatccgc ccaacagttc
    49201 gtggttctgt aatgaaccct aacgatcacc cacacggtgg tggtgaaggt aaagcaccag
    49261 ttggtcgtaa agcaccatct actccatggg gcaaacctgc tcttggtctt aaaactcgta
    49321 acaagaaagc gaaatctgac aaacttatcg ttcgtcgtcg caacgagaaa taatattaaa
    49381 ctagtcgctt aagcaactag taaatccgcc agctcggtag cgctccatag gagtgcaagc
    49441 cgctgtggta caacatttaa aggagaaaat ataaaaatgg gacgcagtct taaaaaagga
    49501 cctttcgtcg atgagcattt gatgaaaaaa gttgaagctc aagctaacga cgaaaagaaa
    49561 aaagttatta aaacttggtc acgtcgttca acgatcttcc caagtttcat tggttacact
    49621 attgcagttt atgacggacg taaacacgta cctgtttaca tccaagaaga catggtaggc
    49681 cacaaacttg gtgaatttgc accaactcgt acttacaaag gtcacgctgc agacgacaag
    49741 aaaacacgta gaaaataagg agaacataaa tggcagaaat tacttcagct aaagcaatgg
    49801 ctcgtacagt acgtgtttca cctcgtaaat cacgtcttgt tcttgataac atccgtggta
    49861 aaagcgtagc cgatgcaatc gcaatcttga cattcactcc aaacaaagct gctgaaatca
    49921 tcttgaaagt tttgaactca gctgtagcta acgctgaaaa caactttggt ttggataaag
    49981 ctaacttggt agtatctgaa gcattcgcaa acgaaggacc aactatgaaa cgtttccgtc
    50041 cacgtgcgaa aggttcagct tcaccaatca acaaacgtac agctcacatc actgtagctg
    50101 ttgcagaaaa ataaggaggt aaaatcgtgg gtcaaaaagt acatccaatt ggtatgcgtg
    50161 tcggcatcat ccgtgattgg gatgccaaat ggtatgctga aaaagaatac gcggattacc
    50221 ttcatgaaga tcttgcaatc cgtaaattcg ttcaaaaaga acttgctgac gcagcagttt
    50281 caactattga aatcgaacgc gcagtaaaca aagttaacgt ttcacttcac actgctaaac
    50341 caggtatggt tatcggtaaa ggtggtgcta acgttgatgc actccgtgca aaacttaaca
    50401 aattgactgg aaaacaagta cacatcaaca tcatcgaaat caaacaacct gatttggatg
    50461 ctcaccttgt aggtgaagga attgctcgtc aattggagca acgtgttgct ttccgtcgtg
    50521 cacaaaaaca agcaatccaa cgtgcaatgc gtgctggagc taaaggaatc aaaactcaag
    50581 tatcaggtcg tttgaacggt gcagatatcg cccgtgctga aggatactct gaaggaactg
    50641 ttccgcttca cacacttcgt gcagatatcg attacgcttg ggaagaagca gatactacat
    50701 acggtaaact tggtgttaaa gtatggatct accgtggtga agttcttcca gctcgtaaaa
    50761 acactaaagg aggtaaataa ccaatgttag tacctaaacg tgttaaacac cgtcgtgagt
    50821 tccgtggaaa aatgcgcggt gaagcaaaag gtggaaaaga agtagcattc ggtgaatacg
    50881 gtcttcaagc tacaactagc cactggatca ctaaccgcca aatcgaagct gctcgtatcg
    50941 ccatgactcg ttacatgaaa cgtggtggta aagtttggat taaaatcttc ccacacaaat
    51001 catacactgc taaagctatc ggtgtgcgta tgggatctgg taaaggggca cctgaaggtt
    51061 gggtagcacc agttaaacgt ggtaaagtga tgttcgaaat cgctggtgta tctgaagaga
    51121 ttgcacgtga agcgcttcga cttgctagcc acaaattgcc agttaaatgt aaattcgtaa
    51181 aacgtgaagc agaataagga gaaggcatga aacttaatga agtaaaagaa tttgttaaag
    51241 aacttcgtgg tctttctcaa gaagaactcg cgaagcgcga aaacgaattg aaaaaagaat
    51301 tgtttgaact tcgtttccaa gctgctactg gtcaattgga acaaacagct cgcttgaaag
    51361 aagttaaaaa acaaatcgct cgtatcaaaa cagttcaatc tgaagcgaaa taatagacta
    51421 gggaaggaga aatttcaatg gaacgcaata atcgtaaagt tcttgttgga cgtgttgtat
    51481 ctgacaaaat ggacaagaca atcacagttg tagttgaaac aaaacgtaac cacccagtct
    51541 atggtaaacg tattaactac tctaaaaaat acaaagctca tgatgaaaac aatgttgcca
    51601 aagaaggcga tatcgtacgt atcatggaaa ctcgcccgct ttcagctaca aaacgtttcc
    51661 gtcttgtaga agttgttgaa gaagcggtca tcatctaatc aaacctgaaa ggagaaaact
    51721 gaaatgattc aaacagaaac tcgtttgaaa gtcgcagaca acagcggtgc tcgcgaaatc
    51781 ttgactatca aagttcttgg tggttcagga cgtaaatttg caaacatcgg tgatgttatc
    51841 gtggcatctg taaaacaagc tactcctggt ggtgcggtta aaaaaggtga cgttgttaaa
    51901 gcagttatcg ttcgtactaa atcaggtgct cgtcgtgctg atggttcata catcaaattt
    51961 gacgaaaacg cagcagttat catccgtgaa gacaaaactc ctcgcggaac acgtatcttt
    52021 ggcccagttg cacgtgaatt gcgtgaaggt ggcttcatga agatcgtgtc acttgctcca
    52081 gaagtacttt aatttttagg aacaaactag tcccctagct tcaagctagg gtgcccttat
    52141 gggcgtaaga aaaatcaagg agaaacctaa tgtttgtaaa aaaaggcgac aaagttcgcg
    52201 taatcgctgg taaagataag ggaacagaag ctgttgtcct tactgccctt ccaaaagtaa
    52261 acaaagttat cgttgaaggt gttaacattg ttaagaaaca ccaacgtcca actaacgagc
    52321 ttcctcaagg tggtatcatc gagaaagaag cagctatcca cgtatcaaac gttcaagttt
    52381 tggacaaaaa tggtgtagct ggtcgtgttg gatacaaatt tgtagacggt aaaaaagttc
    52441 gctacaacaa aaaatcaggc gaagtgcttg attaatcacg aaggaaagga gaagtataat
    52501 ggcaaatcgt ttaaaagaaa aatatcttaa tgaagtagtt cctgctttga cagaacaatt
    52561 caactactca tcagtgatgg ctgtgcctaa agtagataag attgttttga acatgggtgt
    52621 tggtgaagct gtatcaaacg ctaaaagcct tgaaaaagct gctgaagaat tggcacttat
    52681 ctcaggtcaa aaaccactta tcactaaagc taaaaaatca atcgccggct tccgtcttcg
    52741 tgaaggtgtt gcgatcggtg caaaagttac ccttcgtggt gaacgtatgt acgaattctt
    52801 ggataaattg gtatcagttt cacttccacg tgtacgtgac tttcacggtg ttccaacaaa
    52861 atcatttgat ggacgcggga actacacact tggtgtgaaa gaacaattaa tcttcccaga
    52921 aatcaacttc gatgacgttg acaaaactcg tggtcttgac atcgttatcg taacaactgc
    52981 taacactgac gaagagtcac gtgcattgct tacaggcctt ggaatgcctt ttgcaaaata
    53041 atataggagg taaatctaat ggctaaaaaa tcaatggtag ctagagaggc taaacgccaa
    53101 aaaattgttg accgttatgc tgaaaaacgt gctgcattaa aggcggcagg ggactacgaa
    53161 ggtttatcta aattacctcg caacgcctca ccgactcgtt tacataatcg ttgtagagtt
    53221 acggggcgcc cacattcagt ttaccgcaaa tttggtctga gtcgtatcgc ttttcgcgaa
    53281 cttgcgcata aaggtcaaat tcctggtgta acaaaagcat cttggtaatt taagatatca
    53341 agggtgtcaa aactccaagt aaaaatagga aacttgacga agaaactaaa gtttctagga
    53401 aagtttatct ttttcacaca gagtttagcc cgggttcaat tgggcttgcc aatttgaacc
    53461 cgagctacag ctttggcaaa aaagaccaat ttgctttgga gcattgcttc tgcattaaat
    53521 tgtctatttt tgctcgtgct gttacgctct ttgtatcatg tattaactag caagtgcaac
    53581 ttgcaaacta ctagtaagag gagaaaaaca aaatggttat gactgaccca atcgcagact
    53641 tcctaactcg tattcgtaat gctaaccaag ctaaacacga agtacttgaa gtacctgcat
    53701 caaacatcaa aaaagggatt gctgaaatcc ttaaacgcga aggttttgta aaaaacgttg
    53761 aaatcatcga agatgacaaa caaggcgtca tccgtgtatt tcttaaatac ggaccaaatg
    53821 gtgaaaaagt tatcactaac ttgaaacgtg tttctaaacc aggacttcgt gtctacaaaa
    53881 aacgtgaaga ccttccaaaa gttcttaacg gacttggaat tgccatcctt tcaacttctg
    53941 aaggtttgct tactgataaa gaagcacgcc aaaagaatgt tggtggtgag gttatagctt
    54001 acgtttggta aaatcaagat acaaagctcg taaagaacaa agcaaaatta ggaagttgga
    54061 gaagtttgtt tacaaacaag ccaacttatc tattttgcac agttcttaga gcgtgttcag
    54121 ttcagctctt gaactaaata agtatctgaa ccccgtgaaa actggccgtt ctggcctgac
    54181 aatttaacag gagaaaataa acatgtcacg tattggtaat aaagttatcg tgttgcctgc
    54241 tggtgttgaa ctcgctaaca atgacaacgt tgtaactgta aaaggaccta aaggagaact
    54301 tactcgtgag ttctcaaaag atattgaaat ccgtgtggaa ggtactgaaa taactcttca
    54361 ccgtccaaac gattcaaaag aaatgaaaac tatccacgga actactcgtg cccttttgaa
    54421 caacatggtt gttggtgtat cagaaggatt caagaaagaa cttgaaatgc gtggggttgg
    54481 ttaccgtgca cagcttcaag gatctaaact tgttttggct gttggtaaat ctcatccaga
    54541 cgaagttgaa gctccagaag gaattacttt tgaacttcca aacccaacaa caatcgttgt
    54601 tagcggaatt tcaaaagaag tagttggtca aacagctgct tacgtacgta gccttcgttc
    54661 accagaacca tataaaggta aaggtatccg ttacgttggt gaattcgttc gccgtaaaga
    54721 aggtaaaaca ggtaaataat gttgagtggt tgatcatcaa ccaccaacct attttccaac
    54781 tttgtgcata gcacacgatt taaaactaaa gaggtgaaaa ctgtgatttc aaaaccagat
    54841 aaaaacaaac tccgccaaaa acgccaccgt cgcgttcgcg gaaaactctc tggaactgct
    54901 gatcgcccac gtttgaacgt attccgttct aatacaggca tctacgctca agtgattgat
    54961 gacgtagcgg gtgtaacgct cgcaagtgct tcaactcttg ataaagaagt ttcaaaagga
    55021 actaaaactg aacaagccgt tgctgtcggt aaactcgttg cagaacgtgc aaacgctaaa
    55081 ggtatttcag aagtggtgtt cgaccgcggt ggatatctat atcacggacg tgtgaaagct
    55141 ttggctgatg cagctcgtga aaacggattg aaattctaat aggaggacac tagaaaatgg
    55201 catttaaaga caatgcagtt gaattagaag aacgcgtagt tgctgtcaac cgtgttacaa
    55261 aagttgttaa aggtggacgt cgtcttcgtt tcgcagctct tgttgttgtt ggtgaccaca
    55321 atggtcgcgt aggatttggt actggtaaag ctcaagaagt tccagaagca atccgtaaag
    55381 cagtagatga tgctaagaaa aacttgatcg aagttcctat ggttggaaca acaatcccac
    55441 acgaagttct ttcagaattc ggtggagcta aagtattgtt gaaacctgct gtagaaggtt
    55501 ctggagttgc cgctggtggt gcagttcgtg ccgttgtgga attggcaggt gtggcagata
    55561 ttacatctaa atcacttggt tctaacactc caatcaacat tgttcgtgca actgttgaag
    55621 gtttgaaaca attgaaacgc gctgaagaaa ttgctgccct tcgtggtatt tcagtttctg
    55681 atttggcata agaaagggga taaaatggct caaattaaaa ttactttgac taagtctcca
    55741 atcggacgca ttccatcaca acgtaaaact gttgtagcac ttggacttgg caaattgaac
    55801 agctctgtta ttaaagaaga taacgctgct atccgtggta tgattacagc agtatctcac
    55861 ttagtaacag ttgaagaagt aaactaatga agttttaggg gatgtgcact gtaccatccc
    55921 ctaaaactag atatagtcat ctatgatgac atcgtatagg cgagttgatg ggggagacaa
    55981 ccttttctcc cttatcggcg ctagcatttt acaaaagagg agaaaataaa aatgaaactt
    56041 catgaattga aacctgcaga aggttctcgt aaagtacgta accgcgttgg tcgtggtact
    56101 tcatcaggta acggtaaaac atctggtcgt ggtcaaaaag gtcaaaaagc tcgtagcggt
    56161 ggcggagttc gccttggttt tgaaggtgga caaactccat tgttccgtcg tcttccaaaa
    56221 cgtggattca ctaacatcaa cgctaaagaa tacgcaattg tgaaccttga ccaattgaac
    56281 gtctttgaag atggtgctga agtaactcca gttgttctta tcgaagcagg aattgttaaa
    56341 gctgaaaagt caggtattaa aattcttggt aacggtgagt tgactaagaa attgactgtg
    56401 aaagcagcta aattctctaa atcagctgaa gaagctatca ctgctaaagg tggttcagta
    56461 gaagtcatct aagagaggtg acctatgttt tttaaattat taagagaagc tcttaaagtc
    56521 aagcaggttc gatcaaaaat tttatttaca atttttatcg ttttggtctt tcgtatcgga
    56581 actagcatta cagttcctgg tgtgaatgcc aatagcttga atgctttaag tggattatcc
    56641 ttcttaaaca tgttgagctt ggtgtcgggg aatgccctaa aaaacttttc gatttttgcc
    56701 ctaggagtta gtccctatat caccgcttct attgttgtcc aactcttgca aatggatatt
    56761 ttacccaagt ttgtagagtg gggtaaacaa ggggaagtag gtcgaagaaa attgaatcaa
    56821 gctactcgtt atattgctct agttctcgct tttgtgcaat ctatcgggat tacagctggt
    56881 tttaatacct tggctggagc tcaattgatt aaaactgctt taactccaca agtttttctg
    56941 acgattggta tcatcttaac agctggtagt atgattgtca cttggttggg tgagcaaatt
    57001 acagataagg gatacggaaa cggtgtttcc atgattatct ttgccgggat tgtttcctca
    57061 attccagaga tgattcaggg catctatgtg gactactttg tgaacgtccc aagtagccgt
    57121 atcacttcat ctatcatttt cgtaatcatt ttgattatta ctgtattgtt gattatttac
    57181 tttacaactt atgttcaaca agcagaatac aaaattccaa tccaatatac taaggttgca
    57241 caaggtgctc catctagctc ttaccttccg ttaaaggtaa accctgctgg agttatccct
    57301 gttatctttg ccagttcgat tactgcagcg cctgcggcta ttcttcagtt tttgagtgcc
    57361 acaggtcatg attgggcttg ggtaagggta gcacaagaga tgttggcaac tacttctcca
    57421 actggtattg ccatgtatgc tttgttgatt attctcttta cattcttcta tacgtttgta
    57481 cagattaatc ctgaaaaagc agcagagagc ctacaaaaga gtggtgccta tatccatgga
    57541 gttcgtcctg gtaaaggtac agaagaatat atgtctaaac ttcttcgtcg tcttgcaact
    57601 gttggttccc tcttccttgg tgtgatttcc attttaccga ttgcagctaa agatgtattt
    57661 ggtctttctg atgttgttgc ctttggtgga acaagtctct tgatcattat ctctacaggt
    57721 atcgaaggaa tcaagcaatt ggaaggttac ctattgaaac gtaagtatgt tggtttcatg
    57781 gacagaacag aataaaagta tttactgaat cagtaaatac tgagggagtg gaggtttaaa
    57841 ctctgacatt tgtaagagtt ggatctcccc tcttctattt tgtttttaaa tcggggtgaa
    57901 aagacttttt gcttctattt aaaaataaaa taaggagatc aaatcatgaa tcttttgatt
    57961 atgggcttac ctggtgcagg taagggaact caagcagcaa aaatcgtaga acaattccat
    58021 gttgcacata tctcaacagg tgatatgttc cgcgctgcaa tggcaaatca aactgaaatg
    58081 ggtgttcttg ctaagtcata tattgacaag ggtgaattgg ttcctgacga agttacaaat
    58141 ggaatcgtaa aagaacgcct ttcacaagat gatattaaag aaacaggatt cttattggat
    58201 ggttacccac gtacaattga acaagctcat gccttggaca aaacattggc tgaacttggc
    58261 attgaactag aaggtattat caatattgaa gtgaaccctg acagcctctt ggaacgtttg
    58321 agtggccgta tcatccaccg cgtaactgga gaaactttcc acaaggtctt taacccacca
    58381 gttgactata aagaagaaga ttactaccaa cgtgaagatg ataagcctga gacagtaaaa
    58441 cgtcgtttgg atgttaatat tgctcaagga gaaccaatca ttgctcacta ccgtgccaaa
    58501 ggtttggttc atgacatcga aggtaatcaa gatatcaatg atgtcttctc agatattgaa
    58561 aaagtattga caaatttgaa ataaagcgtt tttcacactt gcaaaaatcc gctacaaatg
    58621 ttatactgaa atagtctgac ttataattgt tgtctctgtg tctagaggca tcgaatcgaa
    58681 atttatggag gtgcttttgc gtggcaaaag acgatgtgat tgaagttgaa ggcaaagtag
    58741 ttgatacaat gccgaatgca atgtttacgg ttgaacttga aaatggacat cagattttag
    58801 caacagtttc tggtaaaatt cgtaaaaact atattcgtat tttagcggga gatcgtgtta
    58861 ctgtcgaaat gagtccatat gacttgacac gtggacgtat cacttaccgc tttaaataat
    58921 cgaaaaactt ggagggataa gaaatgaaag taagaccatc ggtcaaacca atttgcgaat
    58981 actgtaaagt tattcgtcgt aatggtcgtg ttatggtaat ttgcccagca aatccaaaac
    59041 acaaacaacg tcaaggataa gatagaaagg agaaaacatg gctcgtattg ctggagttga
    59101 tattccaaat gacaaacgcg tagtaatctc attgacttat gtttatggta tcggacttgc
    59161 aacatctaag aaaattttgg ctgctgctgg aatctcagaa gatgttcgtg tacgtgatct
    59221 tacatcagat caagaagatg ctatccgtcg tgaagtggat gcaatcaaag ttgaaggtga
    59281 ccttcgtcgt gaagtaaact tgaacatcaa acgtttgatg gaaatcggtt cataccgtgg
    59341 tatccgtcac cgtcgtggac ttcctgtccg tggacaaaat actaaaaaca acgctcgcac
    59401 tcgtaaaggt aaagctgttg cgattgctgg taagaaaaaa taatatagga ggtaaaagtc
    59461 ttggctaaac caacacgtaa acgtcgtgtg aaaaagaata tcgaatctgg tattgctcat
    59521 attcacgcta catttaataa cactattgtt atgattactg atgtgcatgg taatgcaatt
    59581 gcttggtcat cagctggtgc tcttggtttc aaaggttctc gtaaatctac accattcgct
    59641 gctcaaatgg cttctgaagc tgctgctaaa tctgcacaag aacacggtct taaatcagtt
    59701 gaagttactg taaaaggtcc aggttctggt cgtgagtcag ctattcgtgc gcttgctgcc
    59761 gctggtcttg aagtaacagc aattcgtgat gtgactccag tgccacacaa tggtgctcgt
    59821 cctccaaaac gtcgccgtgt ataatcatcg cattacactg cttttcgttt aagagggagt
    59881 aactaaatga tcgagtttga aaaaccaaat ataacaaaaa ttgatgaaaa taaagattat
    59941 ggcaagtttg taatcgaacc acttgaacgt ggctacggta caactcttgg taactctctt
    60001 cgtcgtgtac ttctagcttc tctaccagga gcagctgtga catctatcaa cattgatggt
    60061 gtgttacatg agtttgacac agttccaggt gttcgtgaag acgttatgca aatcattctg
    60121 aacattaaag gaattgcagt gaaatcgtac gttgaagacg aaaaaatcat cgaactggat
    60181 gttgaaggtc ctgctgaagt aacagctggt gacattttga cagatagcga tattgaaatt
    60241 gtaaatccag atcattatct ctttacaatt ggtgaaggtt cttctctaaa agcgactatg
    60301 actgttaaca gtggtcgtgg atatgtacct gctgatgaaa ataaaaagga taatgcacca
    60361 gttggaacac ttgctgtaga ttctatttat acaccagtta caaaagtcaa ctatcaagtg
    60421 gaacctgctc gtgtaggtag caatgatggt ttcgacaaat taacccttga aatcttgaca
    60481 aatggaacaa ttattccaga agatgcttta gggctttcag cacgtatttt gacagaacat
    60541 cttgatttgt ttacaaatct tactgagatt gctaagtcaa ctgaagtgat gaaagaagct
    60601 gatactgaat ctgacgaccg tattttagat cgtacgattg aggaactgga cttgtctgtg
    60661 cgttcataca actgtttaaa acgtgccggt atcaatactg tgcatgattt gacagaaaaa
    60721 tctgaagcag agatgatgaa agtacgaaat cttggacgca agagtttgga agaagtgaaa
    60781 ctcaaactca ttgatttggg tcttggatta aaagataaat aaaggaggaa tacatggctt
    60841 accgtaaact aggacgcact agctcacaac gtaaagcaat gcttcgcgat ttgacaactg
    60901 accttttgat caacgaatca atcgtgacaa ctgaagctcg tgctaaagaa atccgtaaaa
    60961 ctgttgaaaa aatgattact ctaggtaaac gtggtgattt gcatgcacgt cgtcaagcag
    61021 ctgctttcgt acgtaatgaa atcgcatctg aaaactatga tgaagcaact gataagtaca
    61081 cttctactac agcacttcaa aaattgttct cagaaatcgc acctcgttat gctgaacgta
    61141 acggtggata cactcgtatc cttaaaactg aaccacgtcg tggtgatgca gcgccaatgg
    61201 cgatcatcga attagtataa aatcatcaat tttgttgagt gttatgatga tggagtcttg
    61261 tgctcttagt ctagctctgg tctaccgcta ggatttcggt cctagcggga acactcatca
    61321 taagttggga tagtagacgc ttgtttacga aattgttttt ttcttaagaa caacttcgta
    61381 agcaggcgtt tttgagtatt ttcgttagaa ttatgctata ctatttgaaa agaatcctgt
    61441 ttaatgttaa ggtttcttat tttaagaaga attggagttt acttatgaaa gccattataa
    61501 ctgttgttgg taaagataaa tctggaattg ttgcaggtgt ttctggtaaa attgcagaat
    61561 taggattgaa tattgacgat atctctcaaa ctgtattgga tgaatatttt acgatgatgg
    61621 ctgttgtatc tagtgatgaa aagcaagatt ttacctatct tcgtaatgaa tttgaagctt
    61681 ttgggcaaac tttgaatgta aaaatcaata ttcagagtgc agcgattttc gaagctatgt
    61741 ataatatcta ggaggtcatc atggatatta gacaagttac tgaaaccatc gccatgattg
    61801 aggagcaaaa cttcgatatt agaaccatta ccatggggat ttctcttttg gactgtatcg
    61861 atccaaatat caatcgtgct gcggagaaaa tctatcaaaa aattacgaca aaggcggcta
    61921 atttagtagc tgttggtgat gaaattgcgg ctgagttggg aattcctatc gttaataagc
    61981 gtgtatcggt gacacctatt tctctgattg gggcagcgac agatgcgacg gactacgtgg
    62041 ttctggcaaa agcgcttgat aaggctgcga aagagattgg tgtggacttt attggtggtt
    62101 tttctgcctt agtacaaaaa ggttatcaaa agggagatga gattctcatc aattccattc
    62161 ctcgcgcttt ggctgagacg gataaggtct gctcgtcagt caatatcggc tcaaccaagt
    62221 ctggtattaa tatgacggct gtggcagata tgggacgaat tatcaaggaa acagcaaatc
    62281 tttcagatat gggagtggcc aagttggttg tattcgctaa tgctgttgag gacaatccat
    62341 ttatggcggg tgcctttcat ggtgttgggg aagcagatgt tatcatcaat gtcggagttt
    62401 ctggtcctgg tgtggtgaaa cgtgctttgg aaaaagttcg tggacagagc tttgatgtag
    62461 tagccgaaac agttaagaaa actgccttta aaatcactcg tatcggtcaa ttggttggtc
    62521 aaatggccag tgagagactg ggtgtggagt ttggtattgt ggacttgagt ttggcaccaa
    62581 cccctgcggt tggagactct gtagcacgtg tccttgagga aatggggcta gaaacagttg
    62641 gcacgcatgg aacgacggct gccttggccc tcttgaacga ccaagttaaa aagggtggag
    62701 tgatggcctg caaccaagtc ggtggtttat ctggtgcctt tatccctgtt tctgaggatg
    62761 aaggaatgat tgctgcagtg caaaatggct ctcttaattt agaaaaacta gaagctatga
    62821 cggctatctg ttctgttgga ttggatatga ttgccatccc agaagatacg cctgctgaaa
    62881 ccattgcggc tatgattgcg gatgaagcag caatcggtgt tatcaacatg aaaacaacag
    62941 ctgttcgtat cattcccaaa ggaagagaag gcgatatgat tgagtttggt ggtctattag
    63001 gaactgcacc tgttatgaag gttaatgggg cttcgtctgt cgacttcatc tctcgcggtg
    63061 gacaaatccc agcaccaatt catagtttta aaaattaaga aaataggaga aattttaagt
    63121 tctatttaag attagacgtg tatactataa tcattaaata aagacctcct aatattattt
    63181 gaaacagata acactgaatt agtttgaatt tgattttcat ctaatatctt tatttaatga
    63241 actcctaaac tttttcataa taatctcctt caaaagtcgc ctgtatgggt ggcttttatt
    63301 ttatcattca tgatataata gaagcaaacg gaggacggaa aatggtaaaa gtacgattgt
    63361 atttggtacg tcatggcaag accatgttta acacgattgg tcgcgcgcaa ggttggagcg
    63421 atactccctt aactgctgaa ggtgaacgag ggattcaaga gttaggaatc ggtttgcgag
    63481 aatctgatct acagtttgag cgcgcttatt cgagtgattc tggtcgtacc attcagacca
    63541 tgggaattat ccttgaagaa cttggcttgc aggggaaaat cccttatcgc atggacaagc
    63601 gtatcagaga atggtgtttc ggtagttttg atggagccta tgatggcgat cttttcatgg
    63661 gcattattcc tcgtatcttt aatgtggacc acgttcacca attgtcttat gctgaactgg
    63721 ctgagggctt ggtagaggtc gatacagctg gttgggctga aggctgggaa aaactcagtg
    63781 gccgaatcaa ggaaggcttt gaaatgattg caaaagaaat ggaagatcaa ggtggaggta
    63841 acgcccttgt tgtcagccat ggaatgacta ttggaaccat tgtttatctg attaatggca
    63901 tgcatccgca tggtctagat aatggtagcg tgacgattct tgaatatgag gacggtcagt
    63961 ttagggttga agttgtcggt gaccgtagtt accgagagct aggacgtgag aagatggaag
    64021 aaggctctat ttaatcagtc tagacttgct tgccatgagc tagggatttg ataagaatat
    64081 caagataaga aaaaacagcc gagggtactc ctttcggctg tttttgatgt ggaaaactaa
    64141 agtgtaatgc tattgctttt agagattttc ataaacaaga gcaaggaacc tactgttaga
    64201 acagtcagga tagttgacaa ggctgcggct acaccgtaat ttcctctgag aacctctgta
    64261 taaatagcta cagtcattgt tcttgttttg acattgtaga ggaggataga agtagagagt
    64321 tttgaaatca ttgtgaccca agataagatg gctccagaaa tgataccaga tagcatcatt
    64381 ggagttgtaa tcttagcaaa ggtattgaga cgactacttc ctaagctttc agcagcttct
    64441 tcaatacttg gtgctatttg ttgtaagcta gcaacagatg agcgaatagt atacggtaat
    64501 cttctgacag atagagacat aatcaagatg aaagcagtcc ctgtaatcat aagaaatcca
    64561 cttccaaata gaccagtatt gaaggaagaa atgaaggcaa tccctagaac ggttcctggt
    64621 acaatataag gtaccatact gaggctgtca attaagtttg taaacaaatt ccgttttcta
    64681 acggctaggt aggagataaa tgtcgcaaat agaacaacta gaactaaggc aatcaaaggg
    64741 atacgaatgg tattgaaaat agcagatccc atacgattga aagctacctt gtaactgttt
    64801 ggagaataac ctttaacaga taccatacct gatgttttta ggaaagaggt ataaattaag
    64861 tagatttgag gtaaaacaga gataaagata attccgtaga ctgttgcata aatggcagct
    64921 atttttcctt ttgtagtttt tttaggctca attggatgga gcagattcat gctgaaactg
    64981 tagcggtttg caatgtgttt ttggataagg aaaattgcca aggcaatgat aatcgccata
    65041 attgcaaaag cagaatttcc tccaacctcg ctaataaatt gggtataaat caggacaggg
    65101 aaagtccgat atccttcgcc aatcaacata ggcgttccaa agtctgagaa tgctctcata
    65161 aatacaagca aggatctgct agtaaggttg gaactaggag aggtaaaaca accgttacga
    65221 tacgcttaaa tccgaaggac cccatgcttt cagctgcttc aagtagagaa ttgtcaatac
    65281 tgttcattgt tccagcaaca tatagaaata ccagtgggaa tagttgcagt gtaaagacaa
    65341 gtacaattcc tttgaatcca taaatatcga tagctggaag atgaagggca tttgtcaaaa
    65401 atttagtgat gacctcattt cgtcccagca agagaattca ggagtaggct cctacgaaag
    65461 gagctgacat ggaagcaatg ataatcaata tttgtagaaa tttcttcccc ttgaagtcat
    65521 acatagagaa gagataagct aatagggttc ctacaactaa ggaagtgata gtagcggtaa
    65581 tggaaacctt gaaactgttg actagtgtct cagagtagta ggctttacta aagaaagtga
    65641 caaaattagc tagtgagaat tgtccttcat gtataagtgc ttgcttgagc acggtaacga
    65701 taggataaac gagaaagata ggataggtaa gaaagaggaa gaaagaggaa gctgtccaaa
    65761 tatttagttt tttacattcc atggttgact ccttttatca gattttggga accatctgca
    65821 gaaaagctgt ttaatttttg cgtattgatt cgtagacgaa tacgattgcc tttttgtaga
    65881 tcttcttcaa aagttgattc ttcactaact tgaatttttg aggcaaaacc tgtctcaatg
    65941 aaatactccg tatttagtcc aagatagacg ctatcgctaa tagttccttc aatatctcca
    66001 gattcatctt tgataaactc ttcgggacga atgcttacat gaatagcttg ctcctcaacc
    66061 tgatcaagag ctagcattcg aagagcatag ccatctgaaa agacgatata agcgccgtcg
    66121 ctccgttttt caagattggc agggataata tttgtgcgtc cgataaaggt tgccacaaac
    66181 tcattagctg gtttatgata gagttctttt ggtcggccga tttgttggat caccccatct
    66241 ttcataacag caatttggtc tgaaatagcc atggcttctt cttggtcgtg ggttacataa
    66301 acagttgtaa ttcccacttc gtgttggatt tctcggatgg cttgacgtat atccaagcga
    66361 agtttggcct ccagattact aagtggctcg tccatgacga gaacacttgg attaaccgct
    66421 aaggcgcatg ccaaggtgac acgttgttgt tgtccaccac tgagtttatc gggctttcga
    66481 tccgcatatt gagcaatttg tatgagttca agatacttgt tggtctgttg aatcaattct
    66541 tcttttggaa ccttcttttg cataagacca aaagcaacgt tgtctcggac agtcaaatgt
    66601 gggaaaatag cgtagttttg gaaaaccatc ccgatattgc gtttgctggg ttccatatta
    66661 ttgatttttg tatcatcgaa gtaaaattct ccatctttga tactgttgaa acctgcaatc
    66721 atacgaagaa gggtcgtttt cccacatcct gaagctccaa gaattttgga attgtaatgt
    66781 tcaaattctc aataacaggg acatcgtggt agattttttt ggcgttaata attttgatct
    66841 cactcatagt gaacctcttt tactgtttag attggatatc tgtaaagact tcgttgtatt
    66901 tcttaacgat atctgattta ttcttgatga cataatcata atcttcagtg agtgttttga
    66961 ttttgtcaat tggtttcatg ttttcgcttg ttttagcatt tttacgaaca ggacggttag
    67021 tagtggttgt accaagtgta tcttgtactt cttgagagat aataaaatcg ataaatttct
    67081 tggcattttc catattttta gattttttaa cgatagcagc actagcaggt aggaagacgg
    67141 ttccttcttt tggatagact accttaatgt tagctccgtc atttaagagt ttaactgctg
    67201 gatcttcata agagagacca acagtcattt ctccatcagc gactgcttta tagacaccag
    67261 atgaacttaa accgatttta tagtatattg aaactagaat agtacacatc tacttctaaa
    67321 atattgttag aaatcgattt gactgtcctg attgatttgt cctgttctta tttcatttta
    67381 ctataccatc aataagtgtg aaaagatctt ttacataaga ccaagcctta tcatctttgt
    67441 aaccaccttg agcttgtagc atatttgtta attgagcaaa ggcgctagaa gagtttgctg
    67501 ggtcggcagt tgcgattttt ccttttagtt caggtttgag aagatcgtta tatccttcga
    67561 tgttcatgcc tttagttaaa tcagggttga cgattaaaac actaccatct agtgtataag
    67621 gagtagagta gccagttgtg ttttgatatt ctttgataac attatcattt tcttttgaag
    67681 tatagttttc aaagagttct ccgtgggtag catattgtgt ataagaacca ccaaagataa
    67741 catcagctac aggaacttct ttttctgact ctagtttttt gaaaagttct ccagtaccag
    67801 cttgaatcag ttctactttg ataccatatt tttcttcaaa ggcaggaata gttgctccaa
    67861 ttaagtcctc tgagtttggt caataaacga ctagcgaacc accgtctcct ttatcagatg
    67921 aactgtcatc ggcagattca ttagaagaac aagcagcata atacatccat ttctttttca
    67981 tgatgggata tctccgttgt gttatttaag tttattttaa aacctacaat tctattctat
    68041 agtatattga atctataaca gtacacttta actgctaaaa tatttctata aattaatttg
    68101 actttcctga tagagatgtt cacatcttat ttcaattcac tatattagag taaaattctc
    68161 tacaaaaaga agaatagcct attttactat tcttccgagt gatttcaatt tctttgggga
    68221 aatatggaga tactttttaa atactttggc aaaatattta tagtctgaaa atccaacttg
    68281 gtcagagata gcgcttaaag gggagttggg agattcagcc atcttatcta tagcttgttt
    68341 caggcgatat tgtaagatat attcatttag agtcatgggg aagtcttctt tgataacctt
    68401 atatagatgc ttgttatctg caaatagcta gagcatttca aggaaatgaa ctagaaataa
    68461 caattaatat ggtggttcag aaataccttt tgataatcaa taagatcttc aggatgaagt
    68521 gcgttgactc catccatttc atatttccga tttaataaac gatatttgtt ttcaccaaat
    68581 tgatgaaaag ggagtagttg aacttggtcg atatttaatg agttaaatag agtagcgaat
    68641 ttttctgcat cctctaaact attgttaaaa ttaggaataa ctgggattct taaaacgata
    68701 gttttatttt gagaaaaagc ataatgaatg tttttaataa tcatttgatt aaaaacccca
    68761 gtcacttttt tatgttttat agaattataa tgttttaggt ctgtgtagat aaaatccaca
    68821 tattgaatta aatcaataaa tttttcatga tcaacaaagg cagtagtttc aatggcagtg
    68881 tgtatgtgat gttctttagc tgattttaag atggctttag caaattcaaa ctgagcaaat
    68941 atttcacctc ctgataaagt taaacctcca ccggattctt cgtaaaattc tttgtctttt
    69001 aatacctctg taataatttc ttctacagtc ttttctttac cgactaaggt gaatttctct
    69061 cgttgagcat ctttcatttt ttcaggtttc attctttgag attcaggatt agaacaccat
    69121 ggacagcgca gaggacatcc ttttaaaaaa acagttgtac gaatacccgg gccgtcatga
    69181 attgaaaagt gttgaatatt aaaaataatt cctttagata tttccataag agttcctcct
    69241 cttcataagt ctatcctatc acaaaaacga aagaaaaaca attacgaacg aaaggttaat
    69301 ttgttgtttt ttgcttttta ttttggtaga ataaaacgga ggtgtaaaat gaaaagattg
    69361 gaacaaatta ttaaattagt atcagaatat gaaaagatcg acgttaatac attatcggaa
    69421 aaattaaatg tatcgaaagt aacgattaga aaagatttag ataaattaga gtcaaaaggt
    69481 ttattacaca gagagcatgg atatgctgta ttaaatagtg gagatgactt aaatgtacgt
    69541 ttgtcaatta attatgaaat taagagaaaa attgttcagg aagcagtaaa attggtgtca
    69601 gataatgaaa caataatgat agaatctgga tcgacctgtg ctttacttgc tgaggaaatt
    69661 tgcaagcaaa aaagaaatgt tacgattgta acaaattcat tttttatagc aaattttgtg
    69721 agagcttatg attcatgtcg tattattgtt cttggtggag agtttcagaa ggattcacag
    69781 gttactgtgg gacctttatt aaaagaaatg atacagactt ttcatgtgca tcaagctttt
    69841 gttgggacag atggttacga taaagagatg ggctttacag gaaaagattt aatgcgcagt
    69901 gaggtagttc aatatatttc agcagcgtcg gataaagtca ttgtactaac tgactcaagt
    69961 aaatttgata aaaggggtac agtaagaaga tttgctttaa gtcaagtcta tgaagtaata
    70021 acagacgaaa aactttctaa acaaaatata gctacattag aaaatgctgg gataatggtt
    70081 aaggtagttt cgtaagaggt taagtgtatg aatcaagata ggaataaact gctttctaaa
    70141 attgcttatc tgtattatat tgaaaactta aatcagtcac aaatagcagc aaaattagga
    70201 atttatagaa cctctattag tagaatgtta acagaagcaa ggaatgcagg aattgttaaa
    70261 attgaaatag agaattttga taccaatatg tttaagttgg aaaattatgt aaaagaaaaa
    70321 tatggtctgg aaagtttaga aattattcca aatgaatttg atgataatcc aacaatttta
    70381 tctgaaagaa tttctcaagt tgcagcaggt gtccttagga atctaattga tgataatatg
    70441 aaaattggct tttcttgggg gaaaagttta agtaatttag tagatttaat tcacagtaaa
    70501 agtgtccgaa atgttcactt ctatcctcta gcaggtggtc ctagtcacat acacgctaaa
    70561 taccatgtga atacactgat ttatgaaatg tctagaaaat ttcatggaga gtgtacattt
    70621 atgaatgcaa cgattgtgca agaaaataaa ttgttagcag atggtatttt gcaatcaaga
    70681 tattttgaaa atttgaaaaa tagttggaaa gatttagata tagctgtagt cggaattggt
    70741 gattttagca ataaaggaaa gcatcaatgg ttagacatgc ttacagagga tgactttaaa
    70801 gaattgacca aagttaaaac tgtaggagaa atttgttgtc gattttttga ttcaaaaggt
    70861 aaagaagtct atgaaaactt acaggaaaga acgatagcaa tctctttgga agatttaaaa
    70921 aatattcctc aaagtttagc tgttgcttac ggtgatacga aagtatcttc gattctttct
    70981 gtcttgcgtg ctaatttagt aaatcatttg attacagaca aaaatacaat tttaaaagtt
    71041 ttggaagaag atggggattt gacttttaga gagattctag gtgagtgaaa atgatagact
    71101 gattcagttt atcgtttttc tttttagttg attgcacatt tgtgcttata taaacaaaaa
    71161 tagtttatct gttgtttttg gattgacaac tttattatgt agttgtattc tatagttaca
    71221 aaagaaaatt ttaaaatttc aaatgaaaaa agctttttac atagtgaaat gaggaggaat
    71281 ttatggaaat tattgttcca gatcaaatta tcatgggttt aattttatat gctggcgatg
    71341 cgaaacaaca tatttataaa gcattagatt acataaagaa cggtacatgt gaacgatgtg
    71401 aagaagaaat ccagttagct gatgcagcct tattagaagc tcataatcta caaacaaaat
    71461 tcttggcaca ggaagcgtct ggtacaaaga cagaaattac agctctcttt gttcattcac
    71521 aagatcatct catgactagt atgacggaga ttaatttaat caaagaaatt attagtttga
    71581 gaaaagaact tcataaaaaa taatactaga gtattatcat tgttattaac atagaggagg
    71641 aaaacataat ggtgaagatt ggtttgtttt gtgcagcagg tttttctact ggtatgcttg
    71701 taaataatat gaaaattgca gcgcaagcta gtggagttga ggcagaaata gaggcgtttt
    71761 ctcagtctaa attagcggat tatgcgccaa atatagatgt tgcactattg ggtccacaag
    71821 ttgcttatac attagataaa tcaaaagaaa tttgtgataa gtgtgatgtt ccgatagctg
    71881 ttattccgat gatggactat ggtatgttag atgggaaaaa agtattagat ttggccctat
    71941 ctttgattag tgggtaagaa aaggagattt attatggcaa agatggatgt tcagaaaatc
    72001 attgcaccga tgatgaagtt tgtgaatatg cgtggcatta tagctctaaa agatgggatg
    72061 ttagcaattt tgccattgac agtagttggt agtttattct tgattatggg acaattgccg
    72121 ttcgaaggat taaataagag cattgctagt gtttttggag ctaattggac agagccgttt
    72181 atgcaagtat attcaggaac ttttgctatt atgggtctaa tttcttgttt ttcaattgcc
    72241 tattcttatg ctaagaatag cggagtagag gctttaccag ctggagttct atctgtatct
    72301 gcattcttta ttttgctaag atcatcttat atccctaaac aaggtgaggc aattggggat
    72361 gctattagta aagtttggtt tggaggtcaa ggaattatcg gtgctatcat tataggtttg
    72421 gtagtaggaa gtatttatac cttctttata aagagaaaaa ttgttattaa gatgccagaa
    72481 caagttccac aagctattgc caaacagttt gaagcaatga ttccagcatt tgtaattttc
    72541 ttactttcta tgattgtata tattttagcg aagtcattga ctaatggcgg aacattcata
    72601 gaaatgattt attctgctat tcaagttcca ttgcaaggtt taactggatc tttgtatggt
    72661 gcaattggaa ttgcattctt tatatcattt ttgtggtggt ttggtgttca tggacaatcg
    72721 gtagtaaatg gagtagtgac agctctgctt ttatctaatc ttgatgctaa taaagctatg
    72781 ttagcctctg ctaatctatc attagaaaat ggtgcacata ttgttactca acaattttta
    72841 gattcatttt taattctatc aggttcaggg attacgtttg gtcttgtagt tgccatgctt
    72901 tttgcagcaa aatcaaaaca ataccaagcc ttaggaaaag ttgcagcttt tccagcaata
    72961 tttaacgtaa atgagccagt tgtatttgga tttccgattg tcatgaatcc agttatgttt
    73021 gtacctttca ttcttgttcc tgtacttgca gctgtgatag tatatggaac tattgcaaca
    73081 ggtttcatgc agccattctc aggggtaaca ttgccttgga gtacaccagc tattttatca
    73141 ggatttttgg tgggtggatg gcaaggagtt attactcagc tggtgatatt agcgatgtct
    73201 acattggttt attttccatt ctttaaagta caggatcgtt tagcttacca aaatgaaatc
    73261 aaacaatctt agaggtattt gtgtgttact gttaaactca cacatttgtg ctaaaaatta
    73321 gagagttaaa atttttctag ttaaaagctt gaaaatttct ataaaaatcg gtattatatt
    73381 ttcgaaagaa ataaaaatat tttcgaaaga aaggtggtta cgatggtaaa tacagaagta
    73441 gcaagaacaa caatcaagac agaatatttt ggcagcctta ctgaaaggat gaacaaatat
    73501 cgagaagatg ttttaaataa aaaaccttat attgatgctg agagagcagt tctagcaaca
    73561 cgcgcctatg aacgatacaa ggaacaacct aatgtcctaa aacgtgcata tatgctgaaa
    73621 gaaattttgg aaaatatgac tatctatatt gaagaagaat ctatgattgc gggaaatcaa
    73681 gcttcttcca ataaagatgc tcctattttt ccggaatata cgctagaatt tgttctcaat
    73741 gagttggatc tttttgaaaa gcgtgatgga gatgttttct atattacaga agaaacaaaa
    73801 gaacaactta gaagtattgc tccgttttgg gaaaataata atttacgtgc tagagctggt
    73861 gccttattac ctgaagaagt gtctgtttat atggaaacag gattcttcgg tatggaaggt
    73921 aagatgaatt ctggagatgc tcacctagca gttaactatc agaaactttt gcaatttggc
    73981 ttaagaggtt ttgaagagcg ggctcgtaaa gcaaaagcag ctctagattt aacagatcca
    74041 gcaagtattg ataaatatca tttttacgac tctatattta tcgtaatcga tgctattaaa
    74101 gtatatgcaa agcgctttgt tgctcttgct aaaagtttag ccgaaaatgc aaatcctaaa
    74161 cgtaagaaag aattacttga gattgcagat atttgctcta gagtcccata tgaaccggca
    74221 actacttttg cagaagctat tcaatcagtt tggtttattc aatgtatttt acaaattgaa
    74281 tctaatggcc actctctttc atatggccgt tttgatcaat atatgtatcc atatatgaag
    74341 gctgatttag aaagtggtaa agaaacagaa gatagcattg ttgaacgtct gacaaatctt
    74401 tggattaaga caattacaat taataaggtt cgcagtcaat cacatacatt ttcttcagca
    74461 ggaagtcctt tatatcaaaa tgttacaatt ggtggacaga ctcgagataa gaaggatgct
    74521 gttaacccat tatcttattt ggtattaaaa tcagttgcac aaacccatct accgcaacct
    74581 aatctaactg tacgttacca tgcaggttta gatgctcgtt tcatgaatga gtgtattgaa
    74641 gtgatgaaac ttggttttgg tatgcctgca tttaataatg atgagattat tattccttct
    74701 tttattgcaa aaggagtatt ggaagatgat gcttatgatt acagtgccat tggatgtgtt
    74761 gaaacggcag ttccagggaa atggggctat cgttgcacag gtatgagtta tatgaacttc
    74821 cctaaggttc tacttatcac gatgaatgat ggaattgatc cggcttcggg taaacggttt
    74881 gcaccaagct ttggtcattt taaggatatg aagaactttt ctgaattaga aaatgcttgg
    74941 gataaaacac taagatattt gacacgaatg agtgttattg ttgaaaattc tattgattta
    75001 tcattggaac gagaagttcc tgatattcta tgttcagcat tgactgatga ttgtattggt
    75061 cgtggaaaac accttaaaga aggtggagca gtatatgatt atatatcagg attgcaagtt
    75121 ggaattgcaa atttgtcgga ttcattagct gcaattaaaa aattggtgtt tgaggaagaa
    75181 cgtataagcc caagtcagct ttggcatgca ctggaaacag attatgccgg agaagaaggt
    75241 aaggtcattc aagaaatgtt gattcatgat gcacctaagt atggtaatga tgatgattat
    75301 gctgacaaat tggttactgc tgcttatgac atttatgttg atgaaattgc taaatatcct
    75361 aatacacgtt atggaagagg tccaattgga ggaattcgtt attcaggaac atcttctatc
    75421 tcagccaacg tagggcaggg acgtggaaca ttagcaactc cagatggacg caacgcgggt
    75481 acaccgttag cagagggttg ttcaccatca cataatatgg atcaacacgg ccctacatct
    75541 gttttaaaat ctgtttcaaa attaccaaca gatgaaatcg taggtggggt tctcttaaat
    75601 cagaaagtaa atcctcaaac gttagccaaa gaagaagata aattaaaact aattgctttg
    75661 ttacgaacat tctttaatcg tttacatggg taccatattc aatacaatgt tgtttccaga
    75721 gagacgctga ttgacgctca gaaacatcct gaaaaacaca gagacttaat tgttcgtgtt
    75781 gcaggatact ctgcattctt caatgttctt tctaaggcaa cccaagatga cattatagga
    75841 cgtactgagc atactttgta aaataaagag gttcttttta tggaatttat gcttgacaca
    75901 ttaaatttag atgagattaa aaagtggtct gaaattttgc cgctagctgg ggtaacttca
    75961 aatcccacta ttgcaaaaag agagggttct attaattttt ttgaacgaat caaagatgta
    76021 agagaattga ttggctctac accctctatt catgttcagg tgatttctca agattttgaa
    76081 ggcatcttaa aggatgctca taaaattcga agacaagcag gagatgatat atttatcaaa
    76141 gtacctgtta ctccagctgg attacgtgca ataaaggcgc taaaaaaaga gggctaccat
    76201 atcactgcaa cagctattta tacagttatt cagggattat tagctatcga agcaggagcg
    76261 gattacctag ctccatatta taatagaatg gaaaatctga acattgattc aaattctgtc
    76321 attcgtcaat tagctcttgc tattgataga cagaactctc ctagtaagat tttagctgca
    76381 tcctttaaaa atgtagcaca agtaaataat gctttagctg caggtgcgca tgctgttaca
    76441 gcaggagcgg atgtttttga atcagctttc gccatgccat ctatccaaaa ggcggttgat
    76501 gatttttctg acgattggtt tgttattcaa aatagtcgtt ccatttagat agagaggaaa
    76561 tacatatgag aatttttgct agtccttcta gatatattca gggggaaaat gccttgtttg
    76621 aaaatgccaa atcaattttg gatttgggaa attgccctat tctattatgc gatcagttgg
    76681 tttatgatat tgttggaaaa cgatttgaag attacctaca taggtatggt ttccatattg
    76741 ttctggcgct atttaatggt gaagcttctg acaatgaaat caatcgagtt gttgccttgg
    76801 ctgagaaaga aaattgtgat agtattatcg gtcttggtgg gggaaagacg attgatagcg
    76861 caaaagctat tgcagatttg attgaaaagc ctgttattat tgctccaaca attgcatcga
    76921 ccgacgcacc tgtatctgct ttatctgtta tttatacaga tgaaggtgca tttgatcatt
    76981 atctatttta ttctaaaaat ccagatttag ttttggttga tacaaaagtt atttcacaag
    77041 cccctaagcg tttattagcg tctggtattg cagatggttt agcaacttgg gttgaggcgc
    77101 gtgcggttat gcaggcaaat ggaaaaacta tgttgggaca acagcaaaca ttggctggag
    77161 ttgcaattgc gaagaaatgt gaagaaacgc tgtttgcaga tggtttacag gctatggcag
    77221 cttgtgaagc taaagtggtg acaccagcat tagaaaatat tgttgaagct aatactttat
    77281 tgagtggtct aggttttgaa agtggaggat tagctgcggc gcatgcaatt cataatggtt
    77341 ttactgcatt gacaggtgac attcatcatt taacacatgg tgaaaaagta gcttatggaa
    77401 ctttagtaca actattattg gaaaatagac ctaaagaaga acttgataag tatattgagt
    77461 tttacaaaaa aattggtatg ccaacaactc taaaagaaat gcatttggat caagttggat
    77521 atgatgattt aataaaagtt ggtaaacaag caactatgga gggtgagaca attcatcaga
    77581 tgccgtttaa gatttcgcct tcagatgttg ctcaagctat tatcgctgta gatgcctatg
    77641 taaattcaaa ataaacaata aggactactg ttttccaaat ggtagtcttt tattgatccc
    77701 tgtattgaat tctatagaag attgaaatag gatgagaaca aatcgattgg gaaagtaaaa
    77761 ttaatttcta taaatgtttt agcaattgtt tcgtactatt tcagattcag tctactatac
    77821 gttcttcata aatcaaaaag cgacataggt agtcggctat ttattgtgag tacattaatt
    77881 agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga gataagcttc
    77941 ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga tagagcaatt
    78001 catagtcatc aaaattaatg agatacagta tacagttttt cctttaaaca catttcaaat
    78061 tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat gagtttttac
    78121 aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca tacatttaag
    78181 acaggaacag atgcatcaaa acctaagttt tatgcgcttg atatgttccc ttatccgtct
    78241 ggagctggtc tgcacgtagg acacccagaa ggttatactg caaccgatat cctcagtcgt
    78301 tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc ttttggtttg
    78361 cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac agcggaaaac
    78421 attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg ggatcgtgaa
    78481 gtcaatacaa cagatccaaa ctactacaag tggactcaat ggattttcac caagctttac
    78541 gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga attgggaact
    78601 gccattgcca atgaagaagt gcttcctgac ggaacttctg agcgtggagg ctatccagtt
    78661 gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga gcgcttgctc
    78721 aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg caactggatt
    78781 ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa ggaatttaca
    78841 gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtctt ggctcctgaa
    78901 catgaattag tagacgctat cacaagttca gagcaagcag aagctgtagc agactataaa
    78961 caccaagcca gccttaagtc tgacttggct cgtacagacc ttgctaagga aaaaactggt
    79021 gtttggacag gtgcctatgc catcaaccct gtcaatggta aggaaatgcc aatctggatt
    79081 gcagactatg tccttgctag ttatggaaca ggtgcggtta tggctgtgcc tgcccacgac
    79141 caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt acttgaaggt
    79201 ggagatgtca aagaagctgc ctacacagag gatggcctgc atgtcaattc agacttccta
    79261 gatgaactca acaaagaaga cgctattgcc aagattgtgg cttggttgga agaaaaaggc
    79321 tgtggtcagg agaaggttac ctaccgtctc cgcgactggc tctttagccg tcaacgttac
    79381 tggggtgagc caattccaat cattcattgg gaagatggaa cttcaacagc tgttcctgaa
    79441 actgaattgc cgcttgtctt gcctgtaacc aaggatatcc gtccttcagg tactggtgaa
    79501 agtccactag ctaacttgac agattggctt gaagtgactc gtgaagatgg tgtcaaaggt
    79561 cgtcgtgaaa ccaacactat gccacaatgg gctggttcaa gctggtacta cctccgctat
    79621 attgatccac acaatactga gaaattggct gatgaggacc tcctcaaaca atggttgcca
    79681 gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta cgctcgtttc
    79741 tggcacaaat tcctctatga cctcggtgtt gttccgacta aggaaccatt ccaaaaactc
    79801 tttaatcaag ggatgatttt gggaacaagc taccgtgacc accgtggtgc tcttgtggca
    79861 accgacaagg ttgaaaaacg tgatggttcc ttctttcatg tagaaacagg ggaagagttg
    79921 gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgttaaccc agacgatgtg
    79981 gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgtttatggg accactcgat
    80041 gcttcgattg cttggtcaga agaaggtttg gaaggaagcc gtaagttcct tgaccgagtt
    80101 taccgtttga ttacaagtaa agaaatcctt gcggaaaaca atggtgctct tgacaaggtt
    80161 tacaacgaaa ctgttaaagc tgtcacagag caaattgatt ccctcaaatt caacacagcc
    80221 attgcccaac ttatggtctt tgtcaatgcg gctaacaagg aagacaagct ctatgttgac
    80281 tatgccaaag gatttatcca attgattgcc ccatttgcac ctcacttggc agaagaactc
    80341 tggcaaactg ttgctgcaac aggtgagtca atctcttacg tgacttggcc aacatgggac
    80401 gaaagtaaac tggttgaaga cgaaatcgaa atcgttgtcc aaatcaaagg taaagtccgt
    80461 gccaaactca tggtcgctaa agacctatca cgtgaagaat tgcaagaaat tgctctagcg
    80521 gatgaaaaag tcaaagcaga aattgacggt aaggaaatcg tgaaagtgat tagtgtacca
    80581 aataaattgg ttaatatcgt cgttaaataa cgagtttatt agctctatct gccaccttca
    80641 atagtccact ggactattga agccaactaa attagttaac attgttgtga aataaaaaga
    80701 agtaactcta gagtatgaac tttagagtta cttttagaat aggtcagaat gaatagatta
    80761 gtgaacgata gcaggaagtg tgaaatttta ttatttaaga tttctattat tgtagtgtca
    80821 gttatagtat tagtaatgtc aatagtgggt gcatattatt ttaaaaattg tctttgggac
    80881 aaggaaagtt taaatttgac actcacttta gacactctct ttgcagtttt tattactttc
    80941 tttagttttt caaatgataa atcaagcaat atttttggaa tatctccaaa tgaaa
//
LOCUS       DAVLCS010000003        78339 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLCS010000003 DAVLCS010000000
VERSION     DAVLCS010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 78339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78339
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.003"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            124..2016
                     /gene="pepO"
                     /locus_tag="VXC78_000214"
     CDS             124..2016
                     /gene="pepO"
                     /locus_tag="VXC78_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV0582367.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEESWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2139..2768)
                     /locus_tag="VXC78_000215"
     CDS             complement(2139..2768)
                     /locus_tag="VXC78_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0582368.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(3108..3350)
                     /locus_tag="VXC78_000216"
     CDS             complement(3108..3350)
                     /locus_tag="VXC78_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582369.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            3761..5983
                     /locus_tag="VXC78_000217"
     CDS             3761..5983
                     /locus_tag="VXC78_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV0582370.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALIYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            6013..6456
                     /locus_tag="VXC78_000218"
     CDS             6013..6456
                     /locus_tag="VXC78_000218"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV0582371.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTDIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6495..6910)
                     /locus_tag="VXC78_000219"
                     /pseudo
     CDS             complement(6495..6910)
                     /locus_tag="VXC78_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7268..7630
                     /locus_tag="VXC78_000220"
     CDS             7268..7630
                     /locus_tag="VXC78_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582372.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEEDVLILLSELQNFFLDVFQAKRIHRA
                     FCVRLCLKAQFLLSNNDS"
     gene            7811..8110
                     /locus_tag="VXC78_000221"
     CDS             7811..8110
                     /locus_tag="VXC78_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582373.1"
                     /translation="MNRDVLEFLRTETAEKISLYISEANRLEGDVTLLAPSSQDLEDI
                     KNAMLSNSNLGLKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(8205..8642)
                     /locus_tag="VXC78_000222"
     CDS             complement(8205..8642)
                     /locus_tag="VXC78_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582374.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLGENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(8744..9409)
                     /locus_tag="VXC78_000223"
     CDS             complement(8744..9409)
                     /locus_tag="VXC78_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV0582375.1"
                     /translation="MAIASGYLNSRLDKFVDWGPWTALVPFGLISVTNVGISMLSTRF
                     TGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQEGRPN
                     QMSQKQVKLAAIIISIIAFLFAFVTNYIGYEGKMNLLAYVTTIAFALSLIANALNALK
                     LTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIEGNSN
                     KEY"
     gene            complement(9597..10247)
                     /locus_tag="VXC78_000224"
     CDS             complement(9597..10247)
                     /locus_tag="VXC78_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV0582376.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     NFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            10359..11201
                     /locus_tag="VXC78_000225"
     CDS             10359..11201
                     /locus_tag="VXC78_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0582377.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMNFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            11277..11714
                     /locus_tag="VXC78_000226"
     CDS             11277..11714
                     /locus_tag="VXC78_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0582378.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            11783..12085
                     /locus_tag="VXC78_000227"
     CDS             11783..12085
                     /locus_tag="VXC78_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582379.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLDFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(12176..13249)
                     /locus_tag="VXC78_000228"
     CDS             complement(12176..13249)
                     /locus_tag="VXC78_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV0582380.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDAELQLYFDLFFGTILDAGISSINDLTSLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            13405..14082
                     /locus_tag="VXC78_000229"
     CDS             13405..14082
                     /locus_tag="VXC78_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0582381.1"
                     /translation="MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            14075..15049
                     /locus_tag="VXC78_000230"
     CDS             14075..15049
                     /locus_tag="VXC78_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0582382.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(15098..17041)
                     /gene="thrS"
                     /locus_tag="VXC78_000231"
     CDS             complement(15098..17041)
                     /gene="thrS"
                     /locus_tag="VXC78_000231"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV0582383.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LEHYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(17099..17275)
                     /locus_tag="VXC78_000232"
     CDS             complement(17099..17275)
                     /locus_tag="VXC78_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0582384.1"
                     /translation="MTKQGRYYDETSYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(17282..17422)
                     /locus_tag="VXC78_000233"
     CDS             complement(17282..17422)
                     /locus_tag="VXC78_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0582385.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(17853..18053)
                     /locus_tag="VXC78_000234"
     CDS             complement(17853..18053)
                     /locus_tag="VXC78_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582386.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPMVILIVSLLYSYRFRFSL"
     gene            18292..18921
                     /locus_tag="VXC78_000235"
     CDS             18292..18921
                     /locus_tag="VXC78_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0582387.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKDQADELDLLRTKNNLNWTFVSSAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKEHISLLEK"
     gene            19062..19331
                     /gene="rpsO"
                     /locus_tag="VXC78_000236"
     CDS             19062..19331
                     /gene="rpsO"
                     /locus_tag="VXC78_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV0582388.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            20147..20761
                     /locus_tag="VXC78_000237"
     CDS             20147..20761
                     /locus_tag="VXC78_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV0582389.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(21053..21802)
                     /locus_tag="VXC78_000238"
     CDS             complement(21053..21802)
                     /locus_tag="VXC78_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV0582390.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            21935..24271
                     /locus_tag="VXC78_000239"
     CDS             21935..24271
                     /locus_tag="VXC78_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV0582391.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNLAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHNYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            24372..25049
                     /locus_tag="VXC78_000240"
     CDS             24372..25049
                     /locus_tag="VXC78_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV0582392.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSK"
     gene            25036..25833
                     /locus_tag="VXC78_000241"
     CDS             25036..25833
                     /locus_tag="VXC78_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV0582393.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            25850..26953
                     /locus_tag="VXC78_000242"
     CDS             25850..26953
                     /locus_tag="VXC78_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV0582394.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQAPANELFPGLQGFDNLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            26954..27034
                     /locus_tag="VXC78_000243"
                     /pseudo
     CDS             26954..27034
                     /locus_tag="VXC78_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            27254..28273
                     /gene="galE"
                     /locus_tag="VXC78_000244"
     CDS             27254..28273
                     /gene="galE"
                     /locus_tag="VXC78_000244"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0582395.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            28275..29240
                     /locus_tag="VXC78_000245"
     CDS             28275..29240
                     /locus_tag="VXC78_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0582396.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFSAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(29291..29497)
                     /locus_tag="VXC78_000246"
     CDS             complement(29291..29497)
                     /locus_tag="VXC78_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV0582397.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            29549..30025
                     /locus_tag="VXC78_000247"
     CDS             29549..30025
                     /locus_tag="VXC78_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV0582398.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            30034..30705
                     /locus_tag="VXC78_000248"
     CDS             30034..30705
                     /locus_tag="VXC78_000248"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV0582399.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            30835..31173
                     /locus_tag="VXC78_000249"
     CDS             30835..31173
                     /locus_tag="VXC78_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV0582400.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            31176..31805
                     /locus_tag="VXC78_000250"
     CDS             31176..31805
                     /locus_tag="VXC78_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV0582401.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            32045..33196
                     /locus_tag="VXC78_000251"
     CDS             32045..33196
                     /locus_tag="VXC78_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0582402.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            33509..34258
                     /gene="truA"
                     /locus_tag="VXC78_000252"
     CDS             33509..34258
                     /gene="truA"
                     /locus_tag="VXC78_000252"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV0582403.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            34248..35021
                     /locus_tag="VXC78_000253"
     CDS             34248..35021
                     /locus_tag="VXC78_000253"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0582404.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            34999..35460
                     /locus_tag="VXC78_000254"
     CDS             34999..35460
                     /locus_tag="VXC78_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0582405.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            35687..37028
                     /locus_tag="VXC78_000255"
                     /pseudo
     CDS             35687..37028
                     /locus_tag="VXC78_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(37156..37359)
                     /locus_tag="VXC78_000256"
     CDS             complement(37156..37359)
                     /locus_tag="VXC78_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0582406.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(37352..38434)
                     /locus_tag="VXC78_000257"
     CDS             complement(37352..38434)
                     /locus_tag="VXC78_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0582407.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(38560..39342)
                     /locus_tag="VXC78_000258"
     CDS             complement(38560..39342)
                     /locus_tag="VXC78_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV0582408.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(39342..40685)
                     /locus_tag="VXC78_000259"
     CDS             complement(39342..40685)
                     /locus_tag="VXC78_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV0582409.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(40784..42100)
                     /locus_tag="VXC78_000260"
     CDS             complement(40784..42100)
                     /locus_tag="VXC78_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV0582410.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            42293..43519
                     /locus_tag="VXC78_000261"
     CDS             42293..43519
                     /locus_tag="VXC78_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV0582411.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            43718..45292
                     /locus_tag="VXC78_000262"
     CDS             43718..45292
                     /locus_tag="VXC78_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0582412.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRIEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKTASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            45557..46345
                     /gene="codY"
                     /locus_tag="VXC78_000263"
     CDS             45557..46345
                     /gene="codY"
                     /locus_tag="VXC78_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV0582413.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            46345..46920
                     /locus_tag="VXC78_000264"
     CDS             46345..46920
                     /locus_tag="VXC78_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0582414.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            47002..47087
                     /locus_tag="VXC78_000265"
     tRNA            47002..47087
                     /locus_tag="VXC78_000265"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47036..47038,aa:Leu,seq:aag)
     gene            47370..48500
                     /gene="ugpC"
                     /locus_tag="VXC78_000266"
     CDS             47370..48500
                     /gene="ugpC"
                     /locus_tag="VXC78_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV0582415.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(48623..48793)
                     /locus_tag="VXC78_000267"
     CDS             complement(48623..48793)
                     /locus_tag="VXC78_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582416.1"
                     /translation="MEIKEQTRKLAVSYSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEYKEHHNIDV"
     gene            49011..49769
                     /locus_tag="VXC78_000268"
     CDS             49011..49769
                     /locus_tag="VXC78_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0582417.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGWLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            49856..50368
                     /locus_tag="VXC78_000269"
     CDS             49856..50368
                     /locus_tag="VXC78_000269"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV0582418.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            50550..51494
                     /locus_tag="VXC78_000270"
     CDS             50550..51494
                     /locus_tag="VXC78_000270"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV0582419.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYRYL"
     gene            51503..52180
                     /locus_tag="VXC78_000271"
     CDS             51503..52180
                     /locus_tag="VXC78_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV0582420.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEISPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            52278..53036
                     /locus_tag="VXC78_000272"
     CDS             52278..53036
                     /locus_tag="VXC78_000272"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV0582421.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            53074..54579
                     /gene="lytC"
                     /locus_tag="VXC78_000273"
     CDS             53074..54579
                     /gene="lytC"
                     /locus_tag="VXC78_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV0582422.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWYGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            55075..55593
                     /locus_tag="VXC78_000274"
     CDS             55075..55593
                     /locus_tag="VXC78_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV0582423.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            55723..56229
                     /locus_tag="VXC78_000275"
     CDS             55723..56229
                     /locus_tag="VXC78_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV0582424.1"
                     /translation="MTKKIVAIWAQDKEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPGELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            56229..56399
                     /locus_tag="VXC78_000276"
     CDS             56229..56399
                     /locus_tag="VXC78_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582425.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            56431..57663
                     /gene="clpX"
                     /locus_tag="VXC78_000277"
     CDS             56431..57663
                     /gene="clpX"
                     /locus_tag="VXC78_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV0582426.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            57672..58259
                     /locus_tag="VXC78_000278"
     CDS             57672..58259
                     /locus_tag="VXC78_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV0582427.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            58270..58650
                     /locus_tag="VXC78_000279"
     CDS             58270..58650
                     /locus_tag="VXC78_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV0582428.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            58702..59592
                     /gene="rapZ"
                     /locus_tag="VXC78_000280"
     CDS             58702..59592
                     /gene="rapZ"
                     /locus_tag="VXC78_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV0582429.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKCLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            59589..60566
                     /locus_tag="VXC78_000281"
     CDS             59589..60566
                     /locus_tag="VXC78_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV0582430.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            60563..61474
                     /gene="whiA"
                     /locus_tag="VXC78_000282"
     CDS             60563..61474
                     /gene="whiA"
                     /locus_tag="VXC78_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV0582431.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHYQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(61508..62473)
                     /locus_tag="VXC78_000283"
     CDS             complement(61508..62473)
                     /locus_tag="VXC78_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0582432.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            62609..63466
                     /locus_tag="VXC78_000284"
     CDS             62609..63466
                     /locus_tag="VXC78_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV0582433.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            63453..64232
                     /locus_tag="VXC78_000285"
     CDS             63453..64232
                     /locus_tag="VXC78_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV0582434.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            64256..65608
                     /locus_tag="VXC78_000286"
     CDS             64256..65608
                     /locus_tag="VXC78_000286"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV0582435.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            65682..66056
                     /locus_tag="VXC78_000287"
     CDS             65682..66056
                     /locus_tag="VXC78_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV0582436.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            66058..66906
                     /locus_tag="VXC78_000288"
     CDS             66058..66906
                     /locus_tag="VXC78_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0582437.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNDPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            67172..67939
                     /locus_tag="VXC78_000289"
     CDS             67172..67939
                     /locus_tag="VXC78_000289"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV0582438.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLPDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            67951..69135
                     /locus_tag="VXC78_000290"
     CDS             67951..69135
                     /locus_tag="VXC78_000290"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV0582439.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQNKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQARGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            69132..71003
                     /locus_tag="VXC78_000291"
     CDS             69132..71003
                     /locus_tag="VXC78_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0582440.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDATLLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQVKDRIGIVGDNGVGKSTLLNLIAGSLEPIAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(71146..72330)
                     /gene="mntE"
                     /locus_tag="VXC78_000292"
     CDS             complement(71146..72330)
                     /gene="mntE"
                     /locus_tag="VXC78_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV0582441.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDILRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            72634..75330
                     /locus_tag="VXC78_000293"
     CDS             72634..75330
                     /locus_tag="VXC78_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0582442.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALITFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            75343..76134
                     /gene="yghU"
                     /locus_tag="VXC78_000294"
     CDS             75343..76134
                     /gene="yghU"
                     /locus_tag="VXC78_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV0582443.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            76250..76660
                     /locus_tag="VXC78_000295"
     CDS             76250..76660
                     /locus_tag="VXC78_000295"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0582444.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETTRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            76672..78267
                     /locus_tag="VXC78_000296"
     CDS             76672..78267
                     /locus_tag="VXC78_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582445.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
BASE COUNT        22971 a        14617 c        17851 g        22900 t
ORIGIN      
        1 atgcgtttta tcatggaaag attttttata atagctaaaa aataatagtt aaatggttat
       61 taattgcatt ccctagtgat ttttgttaag ataaatgcaa atacaaatga aagcgagaac
      121 aagatgacac gttatcaaga tgatttttat gatgctatca atggagaatg gcaacagaca
      181 gctgaaatcc cagcagataa gtctcaaaca ggaggttttg ttgatttaga ccaggaaatt
      241 gaagacctga tgttggcgac aacagacaag tggttagcag gtgaagaagt gcctgaggat
      301 gctatcttgg aaaactttgt caaataccac cgcctagttc gtgattttga caagagagaa
      361 gctgacggta tcacacctgt cttaccactc cttaaagaat tccaagaatt ggaaactttt
      421 gcggatttta cagctaaact agcagagttt gagcttgcag gaaaaccaaa cttccttcct
      481 tttggtgtat cgccagactt tatggatgct agaatcaatg ttctatgggc tagcgctcca
      541 agcacaatct tgccagatac gacctactat gcagaagaac atcctcagcg cgaagaactc
      601 ttgactcttt ggaaagaaag cagcgcaaat ctcctcaagg cttatgattt ctctgatgaa
      661 gaaattgaag acttgctaga aaaaagactt gaattggacc gccgagttgc ggcagtggtg
      721 ctctctaatg aagaaagttc agaatatgct aaactctatc atccatattc ttacgaagat
      781 ttcaagaaat tcgcgcctgc cctacctttg gatgacttct tcaaagcagt tattgggcaa
      841 ttaccagaca aggttattgt agacgaggaa cgtttctggc aagcagcaga gcaattctac
      901 agtgaggaat cctggtctct ccttaaagca accttgattt tgagtgttgt caatctttca
      961 accagctatt taacagagga tatccgtgtt ttgtctggtg cctacagccg tgccctttct
     1021 ggagttccag aggcaaaaga taaggtcaaa gcagcttatc atctagcaca agaacctttc
     1081 aagcaagccc tggggctttg gtacgcccgt gagaagttct ctccagaagc caaggcggat
     1141 gtggagaaaa aagtggcaac catgattgat gtctataagg agcgtctgct taagaatgac
     1201 tggctcactc cagaaacctg taaacaggct atcgtgaagc tcaatgtgat caaaccttat
     1261 attggctatc cagaagaatt gcctgcacgt tacaaggata aggtagtgaa tgaaactgcc
     1321 agtctttttg agaatgctct agcctttgcg cgtgtggaaa tcaagcacag ttggagtaag
     1381 tggaaccagc ctgtagacta taaggaatgg ggcatgcctg ctcatatggt caatgcctac
     1441 tacaatcctc agaagaacct gattgtcttt ccagcggcca ttttacaggc gcctttctat
     1501 gacttgcatc agtcatcttc tgctaactac ggtggtattg gggcagtgat tgcccatgaa
     1561 atttcccacg cctttgatac taacggggct tcctttgacg aaaatggtag cctcaaggat
     1621 tggtggacag agagcgacta tgctgccttc aaggagaaaa cacaaaaagt cattgaccaa
     1681 tttgatggac aggattctta tggagcaacc attaacggta aattgactgt atcagaaaac
     1741 gtggctgact tgggaggaat cgcagcagcg cttgaagcag ctaagagaga agcagacttc
     1801 tcagcagaag agttcttcta caacttcggt cgcatctggc gcatgaaagg tcgaccagaa
     1861 tttatgaaac ttttggctag cgtcgatgtg cacgcaccag ccaaactccg tgtcaatgtg
     1921 caagtaccaa acttcgacga tttctttaca acctatgatg tcaaagaagg agacggaatg
     1981 tggcgttcac cagaggagcg cgtgattatt tggtaataca aaaaatctag tcatcagaaa
     2041 aaaggcatcc aatcatgtgt gaaaaccttg ataggatgcc ttttgtaata gaaagatttg
     2101 ctggatagtt tacttaaatt tcgattgtca tcatcttgct agaaaaaggg attgaaggcc
     2161 ttttcgtgag cgatagtagt agctggacca tgtcctggat agacatcgta gtttggtagg
     2221 gtgaagagtt gggtctggat actatgaagg agttgctcca tgctaccagt cggaaggtcg
     2281 gtccgtccga tagtttcgcg gaatagagca tctcccgtca agactaggtg agcatcagga
     2341 aagactaggg aaacaccacc gatagagtgc cctggggtcg gtagaacctt aaaacgaaat
     2401 tcctctagtt ggtattcttc gtgaaagaca aaggtgtgtt ctgcaggttt tgtgaccaca
     2461 tctgccatat catcgtggcg agggagaccg gagagattat cgacaggagt gtagagccag
     2521 ctggcttcgc tctctgcgat atagacagga ggattgccaa acgtctcgcg aaccaagtcc
     2581 agactcatga tatggtcata atgggcgtgg gtcaagagaa tagcacagat cggtttgttg
     2641 atcttctcga ttgtctgacg aatggcttcc caatgactac caggatcgac gacgatgagg
     2701 tgcttttcgc cttctagata ataggtattt tcataggcaa caggattcac ggttttatgg
     2761 attttcatac tagctccaat ctcaaagaat gtactaatac tcttcgaaaa tctcttcaaa
     2821 ccgcgtcaac tttatctgca acctcaaagc agtgctttga acagcctgcg gctagctttc
     2881 tagtttgctc tttgattttc attgagtata aattaagtat agcacagtta gggagaatag
     2941 gtaaggattt aaaatgaact taaaaaccag cataactaga tgaagacagg ttggttatca
     3001 atttatcaat attggaaagg tgtcaattgc ccttcatagg ttgcataaac tccgtcatta
     3061 gcttgtttga tagacgtgat gtttagagtg ctaccgtagt tggcttctca tttgtcgcta
     3121 tattcactat aagttatcct actgggcagg ttctggtcgt tagcatagta ttgaacgagt
     3181 tttttatagc tttgctggct gaataggaac aggcagcaaa ctcctaacat taggagagca
     3241 aagatagaaa tagcagtttt ttcataggta ttctccttat aaactaaagg atagaagaaa
     3301 gtatcttgag gatttttata ctcttcaaaa atctcttcaa accgcgtcaa cgtcgccttg
     3361 ccgtatatat gtgactgact ttgtcagtct tatctacaac ctcaaagcag tgctttgaac
     3421 agcttgcggc tagtttccta gtttgctctt ggattttcat tgagtattaa ttccaaaatc
     3481 cagtcaaggt accagtgtat gtgatacgag ttccaccgtt tatctttcgt atcttcaatg
     3541 gaattgggga agtcagaaag tctttgggtt acaatatggt ttccgttctt ctatctcttc
     3601 ttctatcacc taagtttaaa atctaacttc gtagtatatt atgggccaat aattcagaat
     3661 tatcaagcaa ttttgaatta tttttttctt attctgttcc aatctagttt tcatattctt
     3721 aaaaaagtga taaaatggta ggaagaattg gagagtagag atgccgaaag aagtgaattt
     3781 aacaggcgaa gaagttgtcg ctttaaccaa agaatattta acggaagagg atgttcattt
     3841 tgtccataag gccttgatct atgctgttga atgccacagt ggtcaatatc gcaaatcagg
     3901 cgagccttat atcattcacc ctatccaagt ggcaggtatt ttagctaagc taaagctgga
     3961 tgctgtaaca gtagcttgtg gattcttgca tgatgtggtg gaagatacag atgcgacctt
     4021 ggacgatttg gaaagagagt ttggtcctga tgtgcgggtg attgttgacg gagttaccaa
     4081 gcttggcaag gtcgagtaca aatcgatcga ggagcaatta gcggaaaatc atcgcaagat
     4141 gctcatggcc atgtctgagg acatccgcgt tattttggtc aaactgtctg accgcttgca
     4201 caatatgcgg accctgaaac atcttcgaaa agacaagcag gagcgtattt ccaaagaaac
     4261 catggaaatc tatgccccac ttgcccatcg tttggggatt tccagtgtca aatgggaatt
     4321 agaagacttg tctttccgtt atctcaatcc aacggagttt tacaagatta cccatatgat
     4381 gaaggaaaag cgcagggagc gtgaggcctt ggtggatgag gtagtcacaa aattagagga
     4441 gtatacgaca gaacgtcact tgaaagggaa gatttatggt cgtcccaagc atatttactc
     4501 aattttccgc aaaatgcagg acaagagaaa acggtttgag gaaatctatg atctgattgc
     4561 tattcgttgt attttagata cccaaagtga tgtttatgcc atgcttggtt acgtgcatga
     4621 attttggaaa ccgatgccag gtcgcttcaa agactatatt gccaaccgca aggccaatgg
     4681 ttatcagtct atccatacga ctgtttatgg accaaaaggg ccgattgaat tccagattcg
     4741 aaccaaggaa atgcacgagg tggctgagta cggggttgcg gctcactggg cttataagaa
     4801 aggtataaag gggcaagtta acagcaagga atcagctatt ggaatgaact ggatcaagga
     4861 gatgatggag ctccaagacc aggctgatga tgctaaggaa tttgtggact ctgttaagga
     4921 aaactatctg gctgaggaga tttacgtttt taccccagat ggagctgtcc gttcccttcc
     4981 caaagattca ggaccgattg attttgccta cgaaatccat accaaggtcg gtgaaaaagc
     5041 aactggtgcc aaggtcaatg gccgcatggt tccactgaca accaagttaa agacagggga
     5101 tcaggttgaa attatcgcca acccgaactc ctttggacct agccgtgact ggctcaatat
     5161 ggtcaagact agcaaggcgc gcaataagat tcgccagttc tttaaaaacc aagataagga
     5221 attgtctgtc aacaagggtc gtgagatgct gatggctcag ttccaagaaa atggctatgt
     5281 ggcaaataaa tttatggaca agcgccacat ggatcaagtt ctgcaaaaga ccagttacaa
     5341 gacagaagac tccctctttg cggccattgg ttttggggaa atcggtgcga ttaccgtctt
     5401 taaccgtctg actgaaaagg aacgccgtga ggaagagcgt gccaaggcca aggctgaggc
     5461 agaggagctt gtcaaaggtg gcgaggtcaa ggttgaaaat aaagaaactc tcaaggtcaa
     5521 gcatgagggg ggagtggtta ttgaaggtgc ttctggtctc ctagtgcgga ttgctaagtg
     5581 ttgtaacccc gtgcctggtg acgatattgt tggctacatt accaagggtc gtggtgtggc
     5641 tattcaccgt gtggactgta tgaacctgcg tgcccaagaa aactacgagc aacgtctcct
     5701 tgatgtggaa tgggaagacc agtactctag ctcaaataag gagtatatgg cccatatcga
     5761 tatctacggt ctcaaccgta caggactgtt gaacgatgta ctgcaagttc tttcaaatac
     5821 aaccaagaat atttcaacgg tcaatgccca accaaccaag gatatgaagt ttgctaatat
     5881 ccatgtgtcc ttcggtattg ccaacctctc tacactgacc acggttgtcg ataaaattaa
     5941 gagtgtgcca gaagtttact ctgtcaaacg gaccaacggc tagttgtcct agctcttact
     6001 agaaaggcta ttatgaaaat cattatccaa cgggttaaaa aagcccaagt gagtatagaa
     6061 ggccagattc agggaaaaat caatcaggga cttttattgc tagttggtgt tggaccagag
     6121 gaccaagagg aagatttgga ctatgctgtg agaaaactgg tcaatatgcg gattttttca
     6181 gacgcagaag gcaagatgaa cctgtctgtc aaagatattg aaggagaaat cctctctatt
     6241 tctcagttta ccctctttgc ggatactaag agaggcaatc gtccagcctt tacaggggca
     6301 gctaaacctg atatggcatc agacttctat gatgctttca atcaaaaatt agcgcaagaa
     6361 gtgcccgttc agacagatat ctttggagca gatatgcagg ttgagctggt taataacgga
     6421 cccgttacca ttatcctaga tactaaaaag agataaaaaa gaccaagccc agtcggcttg
     6481 gtctttctca tctatcataa aatactccaa aaagaaatcg gttcttgata tgcttggggg
     6541 aagtctcttt tcaggctttg gcagatgcga taggaaggga tgagatgtcc taggatgagg
     6601 agagttccct gaaggaaaag tggaatatca cttaaagaca ccaaggagag aatcatcagg
     6661 ctatcccata ggagaatttg taaagcaaaa cgccagaatc tcggtctaat ctgggaatag
     6721 agctgactaa agtggtcaca aagttggttt gaaagatagg tcaatagcac aggatgaaag
     6781 aaaatgagcc aaccgctata aatcaaaatc cagtcccaag taagcccccc tttttaaatg
     6841 tcaaaaatgc cagcatgatt ccatcaatga caaggagttg aatggttttg atgaagatga
     6901 tttttttcat gctaaaacct ccttttcctt agagacactc ccctacaggt attttagaat
     6961 gtatattgct tagatattcc ttattttatt agctttttaa ggtattaaag tagttatata
     7021 agtttatgaa gggtatccta tcctgcacgg ctaattttga gttcgaaact gaggagttta
     7081 taactcaaaa tttcgattaa atcagcattt aacgatagta tgtttgtcat aaaatgataa
     7141 atttttagat tgtggaaatt ttttttaact taattcttga tttttttcta aatgtgatat
     7201 acttaattta cgggataaaa aaaccacctt agaaaggtgt gataatgtgc aaaaagagaa
     7261 tgttagaatg cgtttagcgt ctgaatccag acagatatta gataagctta aagatgatgt
     7321 ttacaataaa ttaggctatg aagtaagcta ttccagtatt gttagtcaag ctgttagaga
     7381 atacgttcct aaaaaagaac gtatagattg gataaaatta aaagagacag ctataccctt
     7441 ttcatcgtta aaacagagca ataattggga gtaccagaca tcacttatgt tagaggaaga
     7501 tgtattaatc ttactgtctg aactacaaaa ttttttctta gatgtcttcc aagcgaaacg
     7561 tatacatagg gcattttgtg tacgcctatg cttgaaagca caatttttat taagtaataa
     7621 tgattcttaa tactatcaat attaatgcgg agtgtaatgc tccgctaaaa taaaacctat
     7681 tacgggataa aaacactact ttatttagga tggaaagagg aacgaatgaa gatgaaagct
     7741 agagattcac cattgaattg attttgtttt tagaaaaaat caataattag aaaaaatacg
     7801 aggtaaaaaa atgaatagag atgtattaga gtttctgaga acagagaccg ctgaaaaaat
     7861 tagtctttat ataagcgagg ctaatagatt ggagggcgat gtaactctac tcgcacctag
     7921 ttctcaagat ttggaagata ttaaaaatgc tatgctttcc aattctaatc tcggattaaa
     7981 agttgcgaga ctggatgtga tgaagaaaat agcatatgct tctacaagaa atcattattt
     8041 aacaggggct acgatttttg gggatatttc gaaaggaaca tacaattgtg atcctaaaag
     8101 ttatgtctaa tataagggag gttaatccct ccccttgttt ttgaaaatcg aaaggaaaag
     8161 tataaaaatg aaagttaatg aatatttctg gagaacgagc tgtcttatac taaaaaagaa
     8221 gaaatcgata aaatagtata cgtgttagag atgtgtttgt cgtaaaagtc tggatagttt
     8281 tctcctaggt agtcagctgt catataataa aaagtagaat ggcaagcagt gataattggc
     8341 ataagagatg aaaaacgctg agaactaatg aaggctaaga gaacaaaaaa tagaaaatca
     8401 atggtgagaa cccctaaata gtagaagcga atctttttat tgatttgagg ataaatctca
     8461 gcgaattgat gtttgagtcg gacgaccaag agaaatagca ggagtccttg agcaaggaag
     8521 aaaattaaac cagagagcaa gagccactca aaagatgtct cgagtctagt gataaaaaat
     8581 gcaaatagta gcaaatcaat aactgcaatt gctataaaat ggattctata gagttttttc
     8641 atgacaagac cttcctcttt tatctaactt cattctactc caaaagaatg ggagttacaa
     8701 ctaaaatgat aaaaatagca gaagggagat tctcttaagt tggctagtat tctttatttg
     8761 agtttccttc tatgtatcta acttcttcat cattccagac aaataaagct ccgattgcat
     8821 tgaggatata aaagatgtat ttaccgatat tggcgaagtt tccttgaata ccagcttttg
     8881 tcagctgaac gaaattgtaa atcaaccaaa agccccactg agttgttagt ttcaatgcat
     8941 tcaaagcatt ggcaatgagg gacagtgcaa aggcaatagt tgttacgtag gcaaggagat
     9001 tcatcttgcc ctcatatccg atatagttgg tcacaaaggc aaagaggaag gcgatgatgg
     9061 aaatgatgat ggccgccaat tttacctgtt tttggctcat ttggttgggt ctgccttctt
     9121 gcgaagcttt ccatttcttt atagcaaagg tataaatgag gaaggtgacg ggataggtaa
     9181 tgatggccgc cttatttcca aggatataat caatagcacc ggacaaaatg gtattaacaa
     9241 taccaaagta atttccccat ttgcttaatt tccccgtgaa acgagtggac aacatggaaa
     9301 tcccaacgtt ggttacggaa atcaatccaa agggtacaag agctgtccat ggtccccagt
     9361 ctacaaattt atcgaggcgt gagttgaggt aaccagatgc aatcgcaatc caacgaccaa
     9421 agcaaccccg aagaggtcaa actatttaga tgtagcaaaa atttttagtg attttttcat
     9481 aggttaaact acctttcttt ttttcaaata ttctcccacc aaatgaaagt aaaataaaat
     9541 gatagaaata aaaccctgaa aataaaactt tcagggttgg taggggactt gagaaattag
     9601 ttgattttct cgacatagag ttgttttgca atgtccatat tcacttgtaa atcctcgtcg
     9661 ttactgagga tagtgaaggt attgctgaag ccatcaaact gcttgacttg gagctggtca
     9721 ccgatgtgaa gtgagtgctt gtccagataa tggagaatgt caaaattatc gtgcacccga
     9781 gtcaggcggt aggcgccagc ttccttgata tcagctagtg ggaggttatt gatttcaacg
     9841 aggagttctc ccttggcagg aatagttcct ccgtgggggc aggttttagg gaaacctagc
     9901 agtttatcta gtctttccac gaacaggtca gagacagtgt gttccaagac ctcagcttcc
     9961 tcgtgaatct ggtcacttgt atagtctaaa tgatgaacta gaaaaacttc aatcaagcgg
    10021 tgcttacgat agagctcaga gactagtttg agaccgaggt cagtcagtag atagccacat
    10081 tccttgtcct ttaggatgag gttttcactt ttcattcgtt tgatcatttc agttacggca
    10141 gggggagaga cttgcatgcg agccgcaatt tccttgttgg taatcttatg caggtctatg
    10201 ccaatttcat aaatacattt tagatagtct tctttgtttg gggtcattcg tttcctcttg
    10261 tctaatatct ttatctagta tatcaaaaaa agctagattt ctctagctgt gactttttat
    10321 gttatactta ttgcaagaga aaaaacgagg agatggatat gacgaaaata gctcttcttt
    10381 cagatattca tggaaatacc accgccttgg aggctgtttt ggcagatgct cggcagctag
    10441 gagtggatga atactggctt ttgggagata ttctcatgcc agggacagga cgtagaagga
    10501 ttttggactt gttggatcaa ctaccgatta cggctagagt tttgggaaac tgggaagaca
    10561 gtctttggca tggtgtccgt aaggaattgg atagtactcg ccccagtcaa cgctatctct
    10621 tgcgccagtg ccagtatgtt ttagaggaaa tttccctaga agaaattgaa gtgctccaca
    10681 atcaacctct tcaaattcat cgtcagtttg gggatttgac ggtgggaatt agtcatcatc
    10741 tgcctgataa gaactggggg cgagagttga ttcatactgg caaacaagag gattttgacc
    10801 gcttggtgac tcatcctccc tgtgatattg ctgtttatgg acatattcac cagcagttgc
    10861 ttcgttacgg gactggtggg caattgattg tcaatccggg ttcgattggc caacctttct
    10921 ttttggacgc tcagctacgg aaggacttgc gggcccagta tatgattttg gagtttgatg
    10981 acaagggcct ggtagatatg aacttccgac gggtagacta cgatgtagca gctgaattgc
    11041 agctggctaa agacctgaga cttccctatt ttgaggttta ctatgaaagt ctggtcaatg
    11101 ggatccacca tactcatcat caggaatttt tgagagaatt ggctcagaaa gagggttgcg
    11161 atcgggagtt agacgactgg ttgaaaagtg gtaacgattg acattacaac taaaaagggt
    11221 ataataatag aaaaagaaga gtagaggcag ggtagcctcg taaaaaggag aagaggatgc
    11281 aaattccaag tagatttacc attgcgactc atatgctgat aatcattgcc ctcgagggga
    11341 aggaaagcaa ggtgaccagt gattttctgg ctgctagtgt cggggtcaat cctgtcatta
    11401 tcagaaagat cttgtcccag ttgaagaagg cagagctgat ttcagtagcg cgtggaacgg
    11461 gcggaacaga gattgtcaag gaccttaagg atattagtct tttagatgtt tatcaggcgg
    11521 tcgaatgtct tggtaagaca ggtcaactct tcagtttcca tgacaatccg aatccaaatt
    11581 gccctgtagg agctcatatt catgatgttt tggatcaaaa attggagaga attcagttga
    11641 ctatggaggc agaacttggt cagaccagtc tagaaaaagt cgtggccgat gcagagagtc
    11701 agatgaagga ttaagaggga taaatgccct ctttttttct ttggataatt atgataaaat
    11761 gtagctatta aaggagtaag aaatgtatct cgttatagga attgtattag cctttatagt
    11821 gtcattttgg aaggataata gaagtttgtg gaatccagta ttatttttat tatccctcat
    11881 ttcaagttat ttttatctat cctacctttt ttataaaaat ggatacgaga atgttcagtt
    11941 agatttttat gtatttgcct ttgtcttact tccttttttg ctttttctaa gtggcatctt
    12001 tttaatctat aatggggtca ttttgttgaa gcgagaggga cgttccaagc cccattatct
    12061 ctcaatgctc tttgattttt attgactatt agattctatt taaaaagact tagaatgcac
    12121 atgaaagtat atattctagg tcttttgttt tgtatacatt taattttcaa gagtattatc
    12181 tatttttcca tgcctggtaa cgagtatcaa tcaataactg ggtaaggcga cccaaggttt
    12241 ctctttcttc tggagtgagg gattgagctt ggacaaagag atgatgaatg tattcaagcg
    12301 cctttaagga agtcaagtca ttgatagagc taataccagc atcaagaata gtgccaaaga
    12361 agaggtcgaa gtagagctga agttctgcgt cagggactgt ggccacccat tctttaaagg
    12421 ttgtgtctac ttgctggcta tcactgttgg tcttatccag ttggacgaag tgcttgtcct
    12481 caatctgcca actaaaggta tcgtgctggg cgatgccacc cagggcagta ctctgaacga
    12541 tgatttggtg agcaggaatt tccagcatca taccgataat ggaaccttgt ggaatgaata
    12601 tcttgcttct atccattatc ctttgataac ccgcagtctg tgtcaattct tgatggagac
    12661 caggtgcatc aaatgtataa actgctgtga tctgattttg caaactttgc tcaatttggc
    12721 tagcagcata gatagcgaga tttcctccct tggaatgccc agccagaata accttttgct
    12781 taggatgatg ggcaaaaaag ttctttaaat agcgaagggc gtgcttttga gcaggaattt
    12841 ccttcatata ggtcaggtgg aaatcttcct tccagccaat gatactgtca tctgtcccac
    12901 gaaagacaat cagataggta tcgaggctga cacgataagt catagccgca aattgctttt
    12961 gcagttcagg gtcgatgtcg ttgataaaat gggagagttt gcaatttttg aagcgcttgt
    13021 gttgagccaa ttcatctaat aattgaaggc gatttttgct agtaagcatg gtgggctctc
    13081 ttggaacctg aggtgctaga tctaaaagac gttgaggaag tgtggagacc agattatcaa
    13141 aggagaggta ggtgatttct attaaggtta gaatgtctaa ctcattcaag ggaaggtcgt
    13201 aataagaatc atatgcgaca tctttcagat agtcaaaaat attggccata agagctcctt
    13261 tctttttatt tatcttagca aatttccctc aaattagcta gtagcattgc ctgtttgtac
    13321 tggctaaaaa caggctattt caaattcagt ttcagaccat ctggcatgga aaaatctgtt
    13381 ataataatag aaaaggagaa gcgcatgcac aagattttat taatagaaga tgatcaggtc
    13441 attcgtcaac aggtcgggaa aatgctctct gaatggggat ttgaagtggt cctggtagaa
    13501 gactttatgg aagttttgag tctatttgtt cagtcggaac ctcatctggt cctcatggat
    13561 attggtttgc ccttgtttaa tggttatcac tggtgtcagg aaatccgcaa gatttccaag
    13621 gtacctatca tgtttctttc ttcgagagac caggctatgg atattgtcat ggcaatcaat
    13681 atgggggcgg atgactttgt gaccaagcct tttgaccagc aggttctttt agctaaggtt
    13741 cagggcttgt tgcgtcgttc ctatgagttt gggcgtgatg agagtttgct ggaatatgct
    13801 ggtgttatcc tcaataccaa atccatggat ttacattatc aagggcaagt cttgaatttg
    13861 accaagaatg aattccagat tttacgcgtg ttatttgagc atgcaggcaa catcgtagca
    13921 cgtgacgacc tgatgcggga actttggaac agtgactttt tcattgatga taataccctc
    13981 tctgtcaatg tggctcgttt gcgtaaaaag ttggaggagc agggattggt aggatttatc
    14041 gagaccaaga aaggaatagg gtacggattg aagcatgctt gattggaaac aattttttct
    14101 agcctatctg cgctcccgta gtcgtctttt tatctatctg ctttctttgg catttcttgt
    14161 cttactcttt cagtttttat ttgccagtct aggaatttac ttcctctact ttttcttctt
    14221 gtgttgcttt gtaaccatct tatttttcac ttgggacata ttggtggaaa cgcaggtcta
    14281 tcgccaggaa cttctctatg gagagaggga agccaagtct cctttggaaa tagctttagc
    14341 agaaaaatta gaagcgcgtg agatggaact ctatcagcag aggtcaaaag cagaaagaaa
    14401 actgacggat ttgctggatt actatacctt gtgggtccat cagataaaga cccccattgc
    14461 agccagtcaa ctcttagttg cagaagtggt cgaccgccaa ctgaagcagc agctagaaca
    14521 ggaaattttc aaaatcgact cctataccaa cctagtttta cagtacctgc gtttagaaag
    14581 tttccatgat gatttgctct taaagcaggt tcaaattgag gacttggtca aggaaataat
    14641 tcgtaaatat gctcttttct ttattcaaaa aggcttaaat gtcaatctac atgaccttga
    14701 taaagaaatc gtgacggata aaaagtggct gctagtggtt attgagcaaa tcatctcaaa
    14761 cagtctcaag tacaccaagg aaggtggtct ggagatttat atggatgacc aagagctttg
    14821 tatcaaagat acgggaatcg ggataaaaaa cagtgatgtc ctccgagtat ttgaacgtgg
    14881 cttttcagga tacaatggcc gtttgaccca gcagtcctct ggacttggcc tttatctatc
    14941 taagaaaatt tctgaagaac tggggcacca gattcgtatc gagtctgagg tcggaaaagg
    15001 aacgacagtg cggattcagt ttgctcaagt gaacttagtc cttgagtaaa aatagatgag
    15061 aaaaagcctc cagattggag gcttttatgc tagactctta tttctcaacg cgtgatttgt
    15121 tggcgatatc agctaggata gcttgaacaa aattatcaac tgagacagtt tgtgtttctt
    15181 tttggccgta gcgacgaacg ttgactgttt cgtcttccat ttctttgtct ccaacaatta
    15241 attggtaagg aatcttgctg gtttgtgaag cacggatctt gaactgcatt ttttcattgc
    15301 gctcatctac gtctgcacgg acaccgcggt cacggagttt cttggccact tcccaagcgt
    15361 agtccacgtg tttttcgtta gatactggga tgagggttac ttggtgtggt gccagccatg
    15421 ttgggaaggc ccccttgtag ttctcaatca agatagctgt gaagcgttcc atagttgaga
    15481 taaccccacg gtggatcatg actggacggt gatcttcgcc atcagctccg atgtatttga
    15541 ggtcgaagcg ttctggcaac aagaaatcaa gttggatagt agaaagggtt tcttcttttc
    15601 caagggcagt tttaatctgg atatccaatt ttggtccgta gaaggctgct tcaccttcgg
    15661 cttcaaagta gtccacgccc atttcatcaa gagctgcacg aagcatggtt tgggcatttt
    15721 cccacatctc atcgttatca aagtacttat gagtatcttg agggtcacga agagagaggc
    15781 ggaagcggta gtcagtcaag ttgaagtctt cataaacatc gataatcaac tgaagggcac
    15841 gttggaattc ttcttggatt tgttctggag taacgaatag gtgaccgtcg ttgagtgaca
    15901 tttcacgtac acgttgaagg ccagtgaggg caccagattt ttcgtaacgg tgcatcatac
    15961 cgatttcagc gatacggatt ggcaattcac ggtaagagtg aacatggtgt ttgaaaactt
    16021 ggatgtggtg cggacagttc attggacgaa ggacaaattc ttccccgtca cccatgtcca
    16081 tggttgggaa catgtcttct tggtaatgat cccagtgacc agaagtcttg taaagctcaa
    16141 cagaagcaag tggtggagtg tagacgtgtt ggtagccaga agccaactct ttgtttacga
    16201 tgtagtgttc caattcacga cggatagtcg caccatttgg caaccagaat ggcaaacctt
    16261 gtcccacttc ttgtgaaatc ataaagaggt caagctcttt accaagttta cggtggtcac
    16321 gttccttagc ttcttcacgc atttgaaggt agtttttcaa gtctttcttg tcaaaccaag
    16381 ctgtaccgta gatacgttgc atcatagcgt tgtcgctgtt tccacgccag tacgcaccag
    16441 ctacatggag aaggtggaag atttggatac gacctgttga tggaacgtga ggtccacggc
    16501 agaggtctac atattcaccc tgacgataga tagtcaaacc gccttcgtct tctgagtgtt
    16561 cttcaatcaa ttccaacttg taagggtcat ttttgaagat ttcacgtgcc tcgtctttag
    16621 tcacttcttc acgaatagat gggaagtttt ctttgacgat tttttgcatt tcttcttcga
    16681 tacgaggaag gtcttcgtta gagatttgac cagctgtgtt gtcagtatcg tagtagaaac
    16741 catcttcgat ggctggacca actcccaagt gaatgtctgg gaaaagacga cgagctgctt
    16801 gggcgaacaa gtgagctgct gagtgacgca agattggaag ggcatcttcg tgatcaggtg
    16861 tcacaatttc gatgcttcca tcttcagtga tagcgcgagt agtgtcgatg agtttgccgt
    16921 tgaatttacc agccaaggct tttttagcta gggaattgct gatagattgg gcaatttcaa
    16981 aagttgttac gccagattcg aattcacgaa cagcgccatc tgggaaagta atgttaatca
    17041 tgatgttctc cttttttatt atttcatagt ttctaagcat tgatttttta tcagcagact
    17101 acttccgagt cctaacgttc aattgctttt ctttatcaga gaggaagttt tccatttccg
    17161 tcagaatgtc tatatccaaa cgttgagaaa gttctaatag ccaccagata ttttctgaaa
    17221 gtttttgttc cagtgtgtag gatgtttcat catagtagcg tccttgcttt gtcatcacca
    17281 gtcattggaa atttccaata tcattagata aagccaagag gtcttcttct accgtccact
    17341 tgaaatcatg atgcttaact tccagttcgt gataagcttg tcggattgcc caactgcgct
    17401 ccactaattc ttgcaactcc ataattagta tcctaataaa aaaatgcgac atcctcgaaa
    17461 ggacgtcgca acgtggttcc accttcattt atgtacctca aaagagaggg acacctctga
    17521 tcggctctaa cgtggccacc gttttatgtt ttcataaaaa actcaagagt agtatcagtt
    17581 tagacttcct atgcgtttcc agcaaccacg cactctctag tagaaaggga ctaagtgact
    17641 tgtctctatg gattattata gcatgattgt gagatttttc aaggattttg tgaaagtttt
    17701 ttgtttttca ttttttgtag aatatgcttg atgctaatac cagaatccat gcccaccaga
    17761 gcaactgttt catagattag caagtaaatt agtataaact caccaaaggt tatgatagta
    17821 aagtaaaaga gcagtccgtt accaactaac catcaaagtg agaaacggaa acggtagcta
    17881 tagagtaacg atacaatcaa gattaccata ggtgtaaaga agagaagatt gtttatatag
    17941 agtcccttga gtgtaagggg gtcagaaaca actagcaaga acaactcata aagtggccaa
    18001 taaaagaata atatgaccag atagtagggg agatgggaat agaatctacg catgataatc
    18061 acctcgtttt aaaaaaacag acaacttaga tctcttgcta tgattattat agcatgttta
    18121 aaacaagaaa gtaaatttgt tgacaaagaa gatttttctt ttcactagaa tcatagttag
    18181 ttttcttggt agaaatattt tgataataat taagcaagac tattgatatt gattattaag
    18241 agtgtcacaa ttgttgtaac taaaatgatt acaacaatag aggtataaaa aatgaaacta
    18301 gcagttattg cagcaaatgg acaagcgggg aaagcaattg ttgaagaagc agtcaaacga
    18361 ggacatgaag taacggctat tgttcgttct gaaaacaaaa gtcaagctga gtctattatt
    18421 aaaaaagatt tatttgagtt gacaaaagat gatcttactg gatttgatgc tgttatttca
    18481 gcgtttggtg cttatacacc agatacgcta ccgctccaca gcaaatcaat cgaactattt
    18541 aatcagcttc ttgctggaac acagacacgt tttctagttg tagggggagc aggaagtctt
    18601 tatatagatg aaacaaaaac gacacgactt ttagatacgt ctgattttcc tgaagaattt
    18661 aagtcactag caaaagatca agcggatgaa ttggatcttc ttcgtacaaa aaataatctc
    18721 aactggactt ttgtcagttc tgctgtagat tttattcccg atggtgaaaa aacaggaaac
    18781 tacattctag caggagaaat ttttactact aatgaaaaag gaataagcca gattagttat
    18841 gcagattatg ctattggatt ggtagatgaa cttgaaaaag gtcatcatat aaaagaacat
    18901 atctctttac ttgaaaaata ataactatga gagtattaat gtttgacaga aaatttaaat
    18961 cttggtaaaa tagggattgt cgtaaagaca aataacttct tcttggttac aggcatgcca
    19021 acctgtcact cggatgaagc caaataaaaa ggagaaacat catggcaatc tcaaaagaga
    19081 aaaaaaatga aatcattgca caatatgcac gtcacgaagg tgatacaggt tcagtagagg
    19141 ttcaagttgc tgtccttact tgggaaatca accaccttaa cgaacacatc aaacaacaca
    19201 aaaaagacca cgctacttac cgtggattga tgaaaaaaat cggtcgccgt cgtaacttgc
    19261 ttgcatactt gcgtaaaaac gacgttaacc gttaccgtga gttgatcaac tctctaggac
    19321 ttcgtcgcta attcaagata caaatgctgt caaaagcaca aagcaaaaat aggaaaattg
    19381 acgaagaaac ttcagtttct aggagatttt atcttttttg ccaagtgctt aggccgtgtt
    19441 caattgagca tatcttgata atgaagctac tctaaattgg gtagcttttt tgcgttgtca
    19501 ccttacctcg atatactcaa gtataatctt tggttacggt tcctagcact gtaaggtaaa
    19561 ataaaccagc ttttctccct tcggggagat tttttttgtt tcactgaaag tttcgtacga
    19621 tcttcgcctc gtcgcctagt ctataaacga tttatctagc aagaatcatg atgctaaggg
    19681 cgtcaaaaat ccgtatgaaa atagggaaat gacacagtgt tcgatgagca caaggagttt
    19741 catctttttc actaggattt tagcccgggc tcaaatcagc tctctgactt cagagggctt
    19801 ttttattgag gttttatcgg taacaatttt ggagactaca aaaacctcaa acggtatcag
    19861 ctaattacac cataaaggtg cgcagttact cggcttttca agccgagtag ctgtatgcaa
    19921 gccccctaga agagcccact ctttacaaag taaagtatag tatgttatac tttacatgga
    19981 agtagtcact gaattccagt tagaaattac tttgtaacta cgttttgagg aggagtaaaa
    20041 tgctttccta cgttcgacat tacccactag cgatagctaa attaatgtgt ctgtgctctc
    20101 ctaaaatctg ctgatttatt actgactaat acaggaggtt ttttttatgg gacagacaat
    20161 catatctgct attggtgttt atatttccac cagtatcgat tatttaatta ttttaattat
    20221 tttatttgca cagctatcac agaataaaca gaaatggcat atttatgcgg ggcaatatct
    20281 aggcacaggc ttacttgtag gggcgagttt agttgctgct tatgtcgtta atttcgtgcc
    20341 tgaagaatgg atggttggat tgcttggttt aatccctatc tatttaggga ttcgctttgc
    20401 aattgttgga gaagatgcgg aagaagaaga ggaagaaatt attgaaagat tagaacaaag
    20461 caaggcaaat caactgtttt ggacagttac attgctgaca attgcgtctg gcggagataa
    20521 tttaggtatc tatatacctt attttgcttc gttagattgg tcacagaccc tcgtggcctt
    20581 gcttgtgttt gtaatcggca taattatctt ttgcgagatt agtagggtgt tatcctctat
    20641 tccgttaata ttcgagacaa ttgaaaaata cgagcgaatc attgtgccct tagtattcat
    20701 tctacttgga ctatacatca tgtatgaaaa tggcacgata gagacttttc tgatcgtgta
    20761 gatttttttg tttcactagg attttagccc gagctcaaat cagctctctg attttcagag
    20821 ggctttttca ttgagtataa atggacaatc ttaaagttac tctattgtag agtggctttt
    20881 gatttgatta ggagattctt ataaatatag taaaatgaaa taagaatagg acaaatcgat
    20941 caggacagtc aaatcgattt ctaaaaatgt tttagaagta gaggtgtact attctagttc
    21001 caatctacta tataaatgaa aaccttagct gtttggccaa ggttcatttc ttctatgcaa
    21061 gttcttctct tttcttatct gggttccaga tgaagcttgc gataaagcta aagatgatgg
    21121 ttaggatagc gaggataata gcaaggatga gggcagggat gcggataaac caccagagtg
    21181 gatttggttt tttatcattg tgccattgtt tcgtttcttc gtccagacgt tggaattctg
    21241 tttgaatacg attggcgact gtttcaatgc cttcatcatt cattttcttg atatctgaga
    21301 tatcgattgg atttccaaag ttcatatcga cacgttcacg gctaatcaag cccttcaaag
    21361 tcatgggacc ggtgtaggta accggcatga tacggacctt ggccattttg gcaatcagtg
    21421 ctgcgccccc cttgacatcg tttgagtggc ggctaccact tggaaacatg atgagagagc
    21481 ggtcactttt tttgagaacg ttgataggat atttgatggc tgaggcgctg ggattttcac
    21541 ggtcgatggg aaaggcgcca cacatacgaa tccaccaacc aaagatacgg ttggtaaaga
    21601 gttctttttt tgccataaag atgaactgtt ttggcttggt cgcaaaggcc atataaacag
    21661 gatcccacca ggtacggtga ggcgcaacta aaatataatt ttcatcttga ttaggaattt
    21721 tatcagtatt atgatagtga gcattgccat tgatggacca taagagcaat acaactaatc
    21781 cacgcaaata agtataaaac atgcgatctc cttcgattgt tttcttgtta ttattatacc
    21841 ttatcaaagg agggctggca aacttttccc ttgactagat acatatttag gatgaaatta
    21901 gaattctgtt aaaaaaaatg atataataga atttatggat aaaaataaga ttatgggatt
    21961 aacccaaaga gaagtcaagg aaagacaggc tgagggtttg gtcaatgact ttaccgcatc
    22021 agccagtacc agcacttggc aaatcgttaa acgaaatgtc tttacccttt ttaacgcttt
    22081 gaacttagcc attgctttgg ctcttgcctt tgtgcaggct tggagcaatc tggtcttctt
    22141 tgctgttatc tgctttaacg ctttttctgg gattgtgacc gagctacgag ccaaacacat
    22201 ggtggacaag ctcaatctca tgaccaagga aaaggtcaaa accatccgtg atggtcagga
    22261 agttgctctt aatcctgaag aattagtgct aggagatgtc attcgtttgt ctgcaggaga
    22321 gcagattcct agtgatgcct tggttttgga aggctttgcg gaagtcaatg aagccatgtt
    22381 aacgggagaa agtgatttgg tgcaaaagga agttgacggc ttacttttgt caggaagttt
    22441 cctagccagt gggtcagttt tatctcaagt tcaccatgtc ggtgcagaca actatgctgc
    22501 caaactcatg cttgaggcta agaccgttaa acccatcaac tcccgtatca tgaaatcgct
    22561 ggacaagttg gctggtttta ctgggaagat tatcattccc tttggtctgg ctctcttgct
    22621 ggaagccttg cttttaaaag gcctgcctct caagtcatct gttgtaaact cgtcgacagc
    22681 tcttttggga atgttgccta agggaattgc ccttttgacc attacttcgc tcttgactgc
    22741 agttatcaag ctaggtttga aaaaggtctt ggtgcaggag atgtactctg ttgagacctt
    22801 ggcgcgcgtg gatatgctct gtctggacaa gacgggtacc atcacccaag gaaagatgca
    22861 ggtggaggct gttcttccgt tgacggaaac gtatggtgaa gaggctattg ccagcatctt
    22921 gactagctac atggcccata gtgaggataa gaatccaact gcccaagcca ttcgccagcg
    22981 ttttgtggga gatgttgctt atcctatgat ttccaatctt cccttctcga gcgaccgcaa
    23041 gtggggggct atggagttag aaggcttggg gacagttttc ttaggggcac ctgagatgtt
    23101 gctggattct gaagtcccag aagccaggga ggccttggag agaggatcac gtgtcttggt
    23161 cttagctctc agtcaggaga aattagacca tcacaaacca cagaaaccat ctgatattca
    23221 ggctctagcc ttgctggaaa tcttggaccc cattcgagag ggagcagcag agacgctgga
    23281 ctatctccgt tctcaggagg taggactcaa gattatctct ggtgacaatc cagttacggt
    23341 gtccagcatt gcccagaagg ctggttttgc ggactatcac aactatgtag attgctcaaa
    23401 aatcaccgat gaggaattga tggccatggc ggaggagaca gctattttcg gacgtgtttc
    23461 ccctcatcaa aagaaactca tcatccaaac gttgaaaaaa gcgggtcata caacggctat
    23521 gacaggggac ggggttaatg atatcttggc ccttcgtgag gcggattgtt ctatcgtgat
    23581 ggcggagggg gatccagcaa cccgtcagat tgccaatctg gttctcttaa actcagactt
    23641 taatgatgtt cctgagattc tcttcgaggg tcgtcgcgtg gtcaataaca ttgcccacat
    23701 cgccccgatt ttcttgataa agaccatcta ttccttcctg ttagcagtca tctgtattgc
    23761 cagtgcttta ctaggtcggt cagagtggat tttgattttc cccttcattc cgatccagat
    23821 taccatgatt gaccagtttg tggaaggttt cccaccattc gttttgactt ttgagcgaaa
    23881 tatcaaacct gtcgagccaa acttcctcag aagatccatg cttcgtgccc taccaagtgc
    23941 cctcatggtc gtgtttagcg ttctttttgt gaaaatcttt ggaacgagtc aaggttggtc
    24001 tgagttagaa atctcaactc tcctctatta tctcttgggg tcaattggtt tcttatccgt
    24061 atttagagcc tgcatgccat tcactctatg gcgagtcctc ttgattgtct ggtcagtagg
    24121 aggcttccta gccacagctc tcttcccaag aatccaaaaa ctgcttgaaa tttcaacctt
    24181 gacagaacaa acgttgcctg tttatggtgt catgatgttg gtctttaccg tgattttcat
    24241 cctgactagt cgctatcaag ctagaaaata aagaaagact gcaatctgtg gattgcagtt
    24301 tttttaggta caagattgcc agccgaaatg tggtataata agaggtaata gagtttggaa
    24361 agtgagagaa aatgatttca aagagattag aattggtagc ttcctttgtg tcacaggggg
    24421 ctattttact agatgtggga agtgaccatg cttatctgcc tatcgagttg gttgagagag
    24481 gccaaatcaa aagcgctatt gcaggtgagg tggtggaagg tccctatcag tctgcggtta
    24541 aaaatgttga ggctcacggc ctaaaggaga aaatccaagt ccgtttagcc aatggcttgg
    24601 cagcttttga agagactgac caagtgtctg tcattaccat tgctggcatg ggtggtcgtt
    24661 tgattgctag gattttagaa gaaggtttgg ggaagttagc taatgtagag cgtttgatcc
    24721 tccagcccaa taatcgtgaa gacgacttgc gtatctggct acaggatcat ggattccaga
    24781 ttgtagcaga aagcatctta gaagaagctg gaaagtttta tgagattttg gtggtggaag
    24841 caggacaaat gaagctatca gccagtgatg ttcgctttgg tcccttcttg tccaaagaag
    24901 tcagtccagt atttgtccaa aaatggcaaa aagaagctga gaagctagag ttcgccctcg
    24961 gacaaatccc agaaaaaaat ctggaagaac gtcaagttct agtagataag attcaagcta
    25021 tcaaggaggt gccccatgtt agcaagtgaa gtgatccaag cttatgaagc cttttgccct
    25081 caggaatttt ctatggaggg agacagccgt ggtctgcaaa ttggcacttt agacaagggt
    25141 atccaaaggg tcatggttgc cctcgatatt cgtgaagaga cagtggcaga ggccattgaa
    25201 aagggtgtgg acttgattat cgtcaagcac gcgcctatct ttcgtcctat caaggacttg
    25261 cttgccagcc gtccgcaaaa tcagatttac atcgacctga ttaagcatga tatcgcagtt
    25321 tatgtcagcc ataccaatat tgatatcgtt gaaaatgggc tcaatgactg gttttgtcag
    25381 atgctaggaa tcgaggagac gacttatctg caggaaacag gtccagaacg tggaattgga
    25441 cgtattggga atattcagcc tcagacattt tgggaattgg cccaacaggt caagcaagtc
    25501 tttgacctag atagccttcg aatggtgcat tatcaagaga atgatttgca gaagcctatt
    25561 tcaagagtag caatttgtgg tggaagcggg cagtctttct ataaggatgc tttggcaaag
    25621 ggggcagatg tctatatcac tggcgacatc tactaccata ctgctcagga tatgctgtct
    25681 gatggcttgt tagcattgga tccaggtcac tatatcgaag tgctttttgt ggaaaaaatc
    25741 gcagcactcc ttactcaatg gaaagagaaa aaaggctggg aactagagat tttacctagt
    25801 caagcatcga ccaatccttt ccgtcatatc tagttagaaa gtgaagacaa tgaaaaaagt
    25861 tgccattatt ggagcaggaa ttgtgggagc aacagctgcc tactacctct cgagagaaag
    25921 tgacctagag gtgaccgttt ttgaccatga gcaaggtcaa gccaccaagg ccgcagcagg
    25981 aattatcagt ccttggtttt ccaaacgccg taataaagcc tggtataaga tggcgcgctt
    26041 gggggctgat ttttatgtgg atttattagc tgatttagag aaatcaggac aagaaatcga
    26101 cttttaccag cgttcgggag tctttctctt gaaaaaggat gaatccaagt tggaagaact
    26161 ctatcaactg gctctccagc gcagagaaga atctcccttg ataggccagt tagccattct
    26221 ggaccaagcc ccagctaatg aattattccc tggcttgcag ggattcgaca acttgctcta
    26281 tgcttctggt ggagcgagag tagatggtca cctcttagta actcgtttgc tggaagccag
    26341 tcaggtcaag ttggtcaaag aaaaagtgac tctgacactc ttatcatcag gctaccagat
    26401 tggcgaagag gtgtttgatc aggttatttt ggcaacggga gcttggttgg gggacatgtt
    26461 agagccttta ggttatgaag tggatgtccg tcctcaaaaa ggacaactac gagattatca
    26521 gcttgtccaa gacatggaag attaccctgt tgtcatgcca gaaggggagt gggatttgat
    26581 tccctttgca ggtgggaaat tatccttggg cgctacccat gaaaatgaca tgggatttga
    26641 tttgacggta gatgaaccct tgctccaaca aatggaggag gcggccttgc ctcattaccc
    26701 agttttagct agagtgactt caagggctga gcgtgtggga atccgtgcct ataccagtga
    26761 tttctctccc ttctttgggc aggtgccaga attggcaggt gtctatgcag ccagtggact
    26821 aggttcatca ggcctcacaa ctggtcctat cattggttac catctagccc aactgatcca
    26881 agacaaggag ttgaccttgg accctctaaa ttacccaatt gaaaactatg tcaaacgagt
    26941 aaaaagcgaa taatactcaa tgaaaatcaa agaacaaact aggaaactag ccgcgggtta
    27001 ctcaaagcac tgctttgagg ttgtggatag aactgacgaa gtcagctcaa aacactgttt
    27061 tgaggttgtg gatagaactg acgaagtcag taaccatacc catggcaagg cgacgttgac
    27121 gtggtttgaa ttggattttc gaagagtata agcattttac tgaaatttta tcaggtagtt
    27181 taggatggca aatgacattc cctgtcaaaa atggtaaaat aagaaaaaat gatctgagaa
    27241 tcgaggaaaa aagatgcaag aaaagatttt ggtaactggt ggtgccggtt ttattggaac
    27301 ccacactgtt attgaattga tccaagcagg ccatcaagtt gttgtggtgg ataatcttgt
    27361 caatagcaat cgtaagagtt tagaagttgt tgaaagaatc acaggagttg agattccttt
    27421 ctatgaggca gatattcgtg acacagatac cctcagagat attttcaagc aggaagaacc
    27481 gactggtgtc attcactttg ctggtttgaa ggctgttggc gaatcaacac gtatccctct
    27541 tgcctactat gacaacaata tcgctggaac tgtcagcctt ttgaaagcca tggaagaaaa
    27601 caactgtaaa aacatcatct tcagttcttc tgcgacagtt tacggggatc cgcacacagt
    27661 gcccatcttg gaagatttcc cactttcagt gacaaaccca tacggtcgta ccaagctcat
    27721 gctagaggaa attttgaccg atatttacaa agcagactca gaatggaatg ttgtcttgct
    27781 tcgttacttt aacccaatcg gagcccatga gagtggtgat ttgggagaaa atccaaacgg
    27841 tattccaaac aatctcttgc catatgtgac tcaagtagcc gttggaaaat tagagcaagt
    27901 gcaagtgttt ggagacgatt acgatacgga agatggaaca ggtgttcgtg actatatcca
    27961 cgttgtcgat ttggctaagg gtcacgttgc agctttgaaa aaaatccaaa aaggttcagg
    28021 actaaacgtt tataaccttg gaactggtaa aggttactca gttcttgaaa ttatccaaaa
    28081 catggaaaaa gcggtgggac gtcctattcc ttaccgcatc gtagaacgtc gcccaggtga
    28141 tatcgctgcc tgctactcag acccagcaaa agctaaagca gaactcggtt gggaagcaga
    28201 actcgacatc acccaaatgt gtgaagacgc atggcgttgg caaagcaagc atccaaatgg
    28261 atttgaagac taagatgatg atttcaatca tcgtcccttg tttaaacgaa gaggaagtac
    28321 ttcctctttt ttatcaggct ctggaagctt tacttccaga tttggaaaca gaaatcgagt
    28381 atgtctttgt cgatgatgga tcaagtgatg ggaccttgga actcttaaag gcctatcggg
    28441 agcaaaatcc ggcagtccat tatatttctt tctctcgaaa ttttggcaaa gaagcagccc
    28501 tttatgcagg cttgcaatat gcgacaggag atttggtggt ggtgatggat gcagacctcc
    28561 aagatcctcc tagtatgttg tttgagatga aaaatgtact agacaaaaat gtagacttgg
    28621 actgcgttgg gacacggaga actagtcggg agggagaacc cttctttcgc agtttctctg
    28681 ctgttctctt ttatcgcctc atgcaaaaaa tcagcccagt agctctgccg tcgggtgtcc
    28741 gtgattttcg tatgatgaga aggtctgtag tcgatgccat tttaagcttg accgagtcca
    28801 atcgtttttc aaaggggctc ttcgcctggg tgggtttcaa aacctactat ttggactatc
    28861 caaatgtcga aaggcaggct ggcaagacaa gttggagttt taggcaactc tttttctact
    28921 ccattgaagg gattattaat ttttcagatt ttcccttgat tatagccttt gtagctggtc
    28981 tcctatcttg ttttctttct ctgctgatga ccttttttgt tgtggttcgg accctcattt
    29041 tgggcaatcc gacatctggt tggacctctc tgatggctgt tattctcttt cttggaggca
    29101 ttcaactctt gaccattggg attctcggca agtatatcag taagatttat ttagagacta
    29161 aaaaaagacc actttatctt atcaaagaaa aaagtgacct tcctgatttt acagaaaaaa
    29221 ataaagtgaa aagactataa ttttacatgg aaatgtgcta aactagaggg agtggattat
    29281 cgccattgat ttaggcttcc tggtttccaa tcagggcgcg agttgggcaa tttttaacag
    29341 cctctaagac atcctgacta ggagaaattt ctttttccag ttggtcaggg tcatcgtaaa
    29401 aacgcacgat tccattatcg tggtaatcaa ataaatcaga ataagtttgg caaagcccac
    29461 aggcgataca tcgttcaggt ataagtgtga ttttcatgtt catatttata ttgtaataag
    29521 aaaagtaaaa aaaaacaagg agtaaggtat ggcaaaagaa ccgtggcaag aagatatcta
    29581 tgatcaagaa gaatcaagag cagagcgtcg gcatcgaaac cacggagggg cggataggat
    29641 ggctaatcgt attttgacga tcctagctag tattttcttt gtaattgtgg tggtgatggt
    29701 catcgttctc atctatctat catcgggggg gagtaatcgc acagcagcct taaaagactt
    29761 tcatgattct gatgcaagtg tagtacaaat ctcatcttca agcagttctc agcctgagca
    29821 gagttcagag ccagaatcta cttctagtag ttcagaagaa gctgctaatc ctgaaggaac
    29881 gattaaagtt ctcgcaggag aaggggaagc agctattgcc gctcgtgcag gaatctccat
    29941 tgctcagtta gaggccttga atcctgggca catggctaca ggatcttggt ttgctaatcc
    30001 aggtgatgtt ataaaaataa aataggagcc gatatgaaaa caattcaaat tgctattgat
    30061 ggtcctgctt ccagcggtaa gagtacggtc gcaaagatta ttgctaagga ttttggattc
    30121 acctaccttg atacaggagc tatgtatcgt gcagcgacct atatggctct taagaaccaa
    30181 ttaggagttg aagaagtcga agcccttcta gccttgttgg accagcatcc aatcagcttt
    30241 ggacgttcag aaactggaga ccagcttgtt tttgtaggag atgtggatat tacccatcct
    30301 atccgtgaaa atgaagtgac caatcatgtt tctgctattg cagcaattcc tgaagtgcgt
    30361 gagaaactgg tttctctcca acaagaaatt gcccagcaag gcgggattgt tatggatggt
    30421 cgcgatattg gaactgttgt attgccgcaa gcagaattga aaattttcct agtagcttct
    30481 gttgatgaga gagcagagcg tcgttacaag gaaaatattg ccaagggaat tgaaacagac
    30541 cttgaaaccc taaaaaagga aattgctgcg cgtgactaca aggatagtca tcgtgagact
    30601 tctcctctca aacaagcaga ggatgctgtc taccttgata caactggttt gaacattcaa
    30661 gaagtagttg aaaaaatcaa agcagaagct gaaaaaagaa tgtaaatgta gaaaagccga
    30721 tagattgata tcggtttttt ctaaatttgt caaaatgctg attttagggt ataatagttg
    30781 ctgttcgaga aattttgatt ttcaaagaat agtgaatgat gataaggaga aatcatgaac
    30841 aatttaccaa attgtccaaa atgtaactca gagtatgtct acgaagacgg tgccctactg
    30901 gtttgcccag agtgtgctca tgagtggaat cctgctgaag ttgcagaagt agaagaaggt
    30961 cttgtcgcta tcgatgccaa cggaaataaa ttgactgatg gtgatacagt aactctcatc
    31021 aaggacttga aagtaaaagg tgcgccaaaa gatttgaaac aagggacgcg cgtgaaaaat
    31081 atccgcatcg tagaaggcga tcacaatatc gactgtaaga ttgatggttt tggtgccatg
    31141 aaacttaaat cagagtttgt gaggaagatt taagcatgtc aaaacactat aaacttgtat
    31201 tttatagccg tatcttcttg tttctagcgg cttttacggg agtttatctt gaaattacta
    31261 ggcatggtgg ttttgggatg cttctctatt acacggttct gtccaacctc ttggtaacta
    31321 tttttaccct ttatcttcta aaggttatga gccgtgtagg tgaaaattgg caaaggccaa
    31381 gtctcttgcg cttaaaaggt ggggtcacca tgagtatcat gattacctgt gtgatttacc
    31441 atttcctctt ggcgcccatt gcgactaatt tctataccct agaaaatttc ctttgccact
    31501 atatcgttcc catctggttt ttagcggata ccctcttttt tgacaaacag ggtcaataca
    31561 agatttggga tccagcagtg tggaccattt taccctttct gtatatgatg tttgctcttt
    31621 ttaatggctt ggttctaaaa ctcaatattc caaatgccaa ggataatcct ttcccttact
    31681 tctttttgaa tgtgaacaag ggttggaatg ttgtgtttaa gtggtgtctg attatctttg
    31741 ttgcctatat ggtagcagga tttattttct actttatcaa gcaaatcaag agaaagtcat
    31801 cctaatactc ttcgaaaatc tcttcaaacc acgttagttt ccatctgcaa cctcaaaaca
    31861 ctgttttgaa caacctgcgg ctagctttct agtttgctct ttgattttca ttgagtatga
    31921 gatacaaggg attcattttc gaatttaaga aggagtctac aaaccaatga ggcttcttct
    31981 tttcttgctt atttgataac tatcaaaaaa gtagaagatt aagagaaata tagaaagaga
    32041 tttcatgaaa caatttttag aacgggccag cattttggct ctctccctcg ttttgattac
    32101 ctccttttcc atttcgagtg ccctaccagc catgtttgac tattatcagg gttattctaa
    32161 ggaacaaatt gagctcttgg tgagcttgcc ttcctttgga atcatgatga tgttactgct
    32221 aaatggtttc ttagaaaaaa tatttcctga gcgcttacag attagtttgg gcttgctgat
    32281 tttatcattg agcggtacag ctcccttctg gtaccaagcc tatccctttg tctttggaac
    32341 acggcttctc tttggtttgg gtcttgggat gatcaatgcc aaggccattt ctattatcag
    32401 tgaacgctac caaggaaaaa ggcgaattca gatgttaggg ctacgcgctt ctgcagaggt
    32461 cgttggagct tctctcatta ccttggccgt cggtcagttg ttggcctttg gttggacagc
    32521 tatctttcta gcctatagtg ctggattttt ggtgatgccc ctttatctgc tctttgtccc
    32581 ttatggaaaa tcaaagaaag aagtcaagaa aagagcgaag gaagcaagtc gtttaactcg
    32641 agaaatgaaa ggcttgattt ttaccttagc tatcgaagcg gcagttgtag tttgtaccaa
    32701 tacagctatt accatccgta ttccaagttt gatggtggaa agaggattgg gggatgccca
    32761 gttatctagt tttgttctta gtatcatgca gttgatcggg attgtggctg gggtgagttt
    32821 ttctttcttg atttctatct ttaaagagaa actgctcctc tggtctggta ttacctttgg
    32881 cttggggcaa atcgtgattg ccttgtcttc atccttgtgg gtggtagtag caggaagtgt
    32941 tctggctgga tttgcctata gtgtagtctt gacgacggtc tttcaacttg tctctgaacg
    33001 aattccagct aaactcctca atcaagcaac ttcatttgct gtattaggct gtagtttcgg
    33061 agcctttacg accccatttg ttctaggtgc aattggctta ctaactcaca atgggatgtt
    33121 ggtctttagt atcttaggag gttggttgat tgtaatctct atctttgtca tgtacctact
    33181 tcagaagaga gcttaggatt gattcctaag tttttctttt gatactcaat gaaaatcaaa
    33241 gagcatagtt gattgagttt ggaatagtac gctgtagctg ctaaaatatt tctagaaatt
    33301 aatttgactt ttctaataga gttattcata tcttatttca atctactata gaaagctagc
    33361 cgcaggttgc tcaaaatagt gttttgaggt tgcagatgga aactgacgtg gtttgaagag
    33421 attttcgaag agtatgagat ttttataccc atacaatatt tgttttaggt ccttgtttac
    33481 agactaattt cttgataaaa tagaggttat gacgagatat aaagcaacta tttcctatga
    33541 tggttatgcc tttgctggct ttcagcgcca gtctcatgcg cgtagcgttc aggaagaaat
    33601 tgaaaaaacc ttgaccagat taaataaagg gcaaaccatt actgttcacg gtgctggtag
    33661 gacagatagt ggggttcatg ccctgggaca ggtcattcat tttgacctgc cttatcagat
    33721 ggatgaggag aaactccgtt ttgccttgga tacccagtct cctgaagata ttgatgtgat
    33781 ttcgattgag cttgtggcag atgattttca ttgccgttat gccaaacata gcaagaccta
    33841 tgagtttatt gtggatagag gacgtcccaa aaatcctatg cgccgtcact atgccaccca
    33901 ctttccctac ccactcgatg tggaacgaat gcagattgca atcaaaaagc tagagggaac
    33961 ccatgatttt accggtttta cagcctctgg gactagtgta gaggataagg ttcgcaccat
    34021 cacagaagct agtttaatag tcgatgagac aggacaattt ttgaccttta ccttttcagg
    34081 aaatggtttc ttgtataaac agattcgcaa tatggtgggg actcttctca aaatcggtaa
    34141 caaccgcatg ccagtagagc agattgatct catcttggag aagaaggaca ggcaacttgc
    34201 aggtcccact gcagcaccaa atggtttgta tttaaaggag attcgttatg aagaataatc
    34261 gtattttagc actttctgga aatgatattt ttagtggtgg tggactgtca gctgatttgg
    34321 ctacctatac cttgaacggc ttgcatgggt ttgtagcagt gacttgtttg acagccttga
    34381 cagaaaaagg atttgaagtc tttccaactg atgataccat ttttcaacat gaattagata
    34441 gcttacgtga tgtggaattt gggggaatta agattggtct tctccctact gtcagtgtgg
    34501 ctgagaaggc cttggacttt atcaaacaac gcccaggagt acctgtggtg ttggatcctg
    34561 tcttggtctg caaggaaacg catgatgtag ctgtcagtga gctctgccaa gagttgattc
    34621 gctttttccc ttatgtcagt gtgattacgc ctaatctccc agaagcagaa ttattatccg
    34681 gtcaggaaat taaaaccttg gaagacatga aaactgcagc gcagaaattg catgatttag
    34741 gagcgccagc agtcattatc aagggaggca atcgtcttag tcaggacaag gctgtggatg
    34801 tcttttatga tggacagacc tttactatcc tagaaaatcc agttatccaa ggccaaaatg
    34861 ctggtgcagg ttgtaccttt gcctctagca ttgccagtca cttgattaaa ggtgataaac
    34921 ttttgccagc agtagaaagc tctaaggctt tcgtttatcg tgctattgca caagcagatc
    34981 agtatggagt aagacaatat gaagcaaaca aaaacaacta aaatcgccct tgtatcccta
    35041 ttaaccgccc tttctgtggt tctaggttat ttcttaaaaa tcccaacacc tacaggaatt
    35101 ctaactcttt tagatgctgg tgtcttcttt gcggcctttt actttggtag tcgtgaagga
    35161 gcggtagtcg gaggactagc aagtttcttg attgacctct tatcaggcta ccctcagtgg
    35221 atgttcttta gcttggtcaa ccatggcttg cagggatttt tcgcaggatt taaaggaaaa
    35281 agtcagtggt taggccttat tttagcaact attgccatgg taggaggcta cgccttgggt
    35341 tctactttga tgaatggctg ggcagcagcc ctcccagaaa ttctaccaaa tttcatgcaa
    35401 aatatggtag ggatgattgt aggatttatt cttagtcaaa gtatcaagaa gattaagtaa
    35461 tactcttcga aaatctcttc aaaccacgtc agcttccatc tgcaacctca aaacactgtt
    35521 ttgagcagcc tgaggctagc tttctagttt gcactttgat tttcattgag tataaagagg
    35581 ttgagtaaaa agtatttcaa ataagaaaaa cgcatagtat caggtgttga atgaactgcc
    35641 ccccaaaagt tagacagaaa aaatctaact tttggggtgt tttattatga aactaactta
    35701 tgatgataaa gttcagatct atgaacttag aaaacaagga tatagcttag agaagctttc
    35761 aaataaattt gggataaaca attctaatct taggtacatg attaaattga ttgatcgtta
    35821 cggaatagag ttcgtcaaaa aagggaaaaa tcgttactat tctcctgatt taaaacaaga
    35881 aatgattcat aaagtctgac atgaaggcta gactaaagat agagtttctc ttgaatacgg
    35941 tctcccaagt cgtacgatac ttcttaactg gctagcacaa tacaggaaaa acgggtatac
    36001 tattgttgag aaaacaagag ggagagtacc taaaatggga cgtaagccaa aaaagagacc
    36061 tgaagagagg acagaattag aacgtcttca agcagaaaat gagtacctga gagcggagaa
    36121 tgccatccta aaaaagttaa gagaactccg attgaaggag gaaaaagaga aagacagaaa
    36181 ttgtttaaga attaatgact gagttttcgt tagatcttct tctaaaagcc attaaactag
    36241 ctcgttcgac ctactactat cacttgaaac agctagacaa aacagataag gaccaagagc
    36301 ttaaagctga aattcaatcc atttttatcg aacacaaggg aaattatgct tatcgtcgaa
    36361 ttcatttaga actaagaaat cgtggttatc tggtaaatca taaaagagtt caaggcttga
    36421 tgaaagtact caatttacaa gctaaaatgc gacagaaacg aaaatattct tctcataaag
    36481 gagacgttgg taagaaagca gagaatctca ttcaaggcca atttgaaggc tctaaaacaa
    36541 tggaacagtg ctacacagat gtgactgaat ttgccattcc agcaagtact caaaagcttt
    36601 acttatcacc agttttagat ggctttaata gcgaaattat cgcctataat ctttcaactt
    36661 cacccaactt agaacaagta caaacaatgt tggaacaggc attcacagag aagcactacg
    36721 agaatacgat tctccatagt gaccaaggct ggcaatatca acacgattct tatcatcagt
    36781 ttcttgaggg taagggaatt caagcatcca tgtcacgcaa gggaaacagc caagacaacg
    36841 gtatgatgga gtccttcttt gggattctga aatcggaaat gttttacggt tatgagaagt
    36901 cgtttcagtc gcttaagcaa ttggaacaag ctattgtaga ctatattgat tactacaaca
    36961 ataaacgaat taaggtaaaa ctaaaaggac ttagtcctgt gcaatacaga actaaatcct
    37021 tcggataaat tatttgtcta actgtttggg ggcagtacat tttaacactt gatactatgc
    37081 gttttattgt gggaagattt tcctcatttt ctagtgaaat tgaacttttt ctaacatctt
    37141 ttgatagatg acttcttaat caattatcat ttccattgtt gtttcttggg gtttcatccc
    37201 ttgtctttga taaaagcgga gagcaccctc gttatcattc cagacactta gggttagatt
    37261 attgcagcca atttctttag cataatagca gaaaaatgac aataaaatag cccctagata
    37321 ttttgaaagg aaagcatagg ggctatatag tttaatcaaa ataaagcaaa tctttgctgg
    37381 tgcttgtaaa gaggtcgaag ccatccttgg taacaacacc gcagtcttca atacgaacac
    37441 cgactttacc agggatatag atacctggtt caacagagaa gcacatgcct tcttcgatga
    37501 ccatgtcgtt tccttccatg atagatggga attcatggac atccataccg ataccatgcc
    37561 cgagacggtg gttgaagtac tcaccataac cagctttttc gatgacctca cgggcagcgc
    37621 ggtccacttc atgagcagtc acacctggct tgataaagtc aagagcagct tgttgggctt
    37681 caagagtcaa gttgtaaata tctttcttga attggtctgg tttgccgaca gcgactgtac
    37741 gagtcatatc tgacgcatag ccattgacca gaacacccag gtcaaagagg agaagagcat
    37801 cattttcaac cttattagct gctggaatgc cgtgtggatt cgcagcatta tcaccagtca
    37861 agaccatggt atcaaagctc atttcataac cttcacgttt catggcaaag tcgatttgtg
    37921 cgatgatatc tgtctcagtc ttatcaagag aaatattgtc aaaaccaaca tgaacagcct
    37981 tgtcagcata aagacctgca accatcattt tttgcacttc atcagctgat ttgatgaggc
    38041 gcatgcgttg gatacgagga gtgaggttgt caaactcagc agtctcaaaa actgttttca
    38101 aaccatggta tttggtcaag atgagattgt caaactcaac agcgacacgt ttgaagtcaa
    38161 gttgtggaag agcatgtttg attttttgcc atggattttc agaatcgaca tagcccacta
    38221 ctgggaagga aacggtgcta cttgcacgtt ctacttcaag agctgggaca aagaggagag
    38281 gttcctgatc cgctaggaca aagaggaaca tttggcgttc atggggatca ctgtaaaaac
    38341 cagtgaggta attgattgtg acggggtcag atacgacagc gacgtctagt ttttctgatt
    38401 caagatatgt taggatttgt tgtaatttag acatatgcta ccttctttct acccctctat
    38461 tttggcaaaa aatgagagaa aatgcaaggg agaagggtaa aagaaaagac aaaaaactcc
    38521 gacaagataa cggagttctt tgatatcatt ttcctttgtt taagaaaagt cagccttgct
    38581 tttgacgtca ctgtactctt cagcgatttc ttggctgaga atgtcctcat aggcagggag
    38641 ttggatgtcc tgaccatatt tcttcttgag ggcagtagta actaggcgat aagccagatt
    38701 ggcattacga gagaggatag gcccgtggaa gtaggaacca aagacattct tataatgaac
    38761 cccttcaccg accttttctt cgttgtttcc atttccatag acaacctgtc ccagcggttt
    38821 ttggtcatca gagaggaagg tacgaccttg gtgattttca aatccatagt aggtttcatc
    38881 gaaatcttca ttgtgaatct tgatgtcacc gataaaacgg ttattggtct ggttgagcgt
    38941 gtagtgtccc atgaccccta gcccttcgat acgttttcct gaagcttcaa cataatattg
    39001 acccaatagt tggaaaccac cgcagatagc cagaactaca ccgtcgtttt ggatgtagtt
    39061 gtcaatgctc tcttttttag caggtaggtc gtctgcaatg atactttgtt caaagtcttg
    39121 accaccaccg aaaaaggcga tgtcgtagtg attttcatca aagtcatcat ggagagaaac
    39181 gatgtcaacg gtcacatggg ctcccagttt ttcagccaca tacttgagca tgaggatgtt
    39241 tccattgtcc ccgtaggtat tcatgagatt tccgtagagg tgggcaatgt tgagctgata
    39301 ggggtaattg ctatcttttg aggaaagtga agtataaacc attagttcat ctcctttcta
    39361 acaatctgac gactagccag cagttcacga aattccagca tggcagtata agttgccaga
    39421 atataggcat gcttgcagtc ttgattctca atggtcttga gaacttgctc cagattactc
    39481 gtttcagtga ttttctcagc tggatagcca gtcactcgga ggcgacgagc gatttcagaa
    39541 tgacgaacac cgccagcgtt gatttcagga atgtccatgt cagtgatttg ctcaaagtct
    39601 gcatcccaga tccagctagt gtcaattcca tctgcatagt tggcattaag gaggacagat
    39661 aggctaaatg gataaggtgc tagtttgatc atttcgatag cttgggttgc accgactgga
    39721 tttttaatca agacaagggt acattccttg tcaccgatat gaaaggtttc ttggcgtcca
    39781 aagacagcac ggctcttgtc aaatccctgt ttgatgagtt gggaatctgc gccgaggaaa
    39841 cgggcgatgg ccacagcagc tagggcgtta tagatattat agagcccgcc gatttggata
    39901 ccgtattctt ggccgtctat gacaaagcga gagcgattgt tggtcaactc aaccagtttt
    39961 gtcaaacgat agtcgagatc aggacgttta catccacaac cttcacagat ataggcaccc
    40021 aagtttgcat aggtattatg ctcatatttg aggatgcctt ggcagtcagg acagagaatc
    40081 ccttcggtat tgtagtgagc aagttgggct ggtccttttt ccaagtcaaa accaaaatac
    40141 tctatagggt ttggaatagt tggcttgtag aaaagtggac tgtctccgtt aaggagaaca
    40201 gtagcagttg gaacttttcg aatggcatcc aatatcatgt tataggtagt atagatttca
    40261 ccgaaacggt ccatctggtc acggaagata ttagtaatga caaaaagact aggctggata
    40321 tagtcacaga tacgagatag actggcttcg tcaatttcga ggacggcaat atttttccca
    40381 gtttttgaag atttggctgt taggaaggtt gttgcaatcc ctgtaatcat gttggcaccg
    40441 cttgggttgg ttagaacttg accataaacc tcttttaaaa tgccgacagt gagggcagtt
    40501 gtcagggttt ttccatttgt tccagtgaca acgacaatct cgtagttctt agctaggctt
    40561 tgtaaaatat ctttatcaaa ttgaagggcg actttccctg ggagcgtact tccacgtcca
    40621 agacggctta aaacgaagtg ggaagaacgc ccagcaagaa ggcccaaagt agtttttaag
    40681 ttcatgtttc tattatatca caaaagaggg aaaagacaga tttggtgttt cgtagaagta
    40741 aaaacagccc aaagagggct gtcagttaag atgagatttc aacttaaatc gcaaacaagt
    40801 cattcaagtt ctcagccaag gttgggtgag tgaagatttg ttttgtgaag taagtgtaag
    40861 gaatcttgtt gtccatagca acagtaatga tgttgatgat ttcttgagaa ccttctgaga
    40921 agatgcttgc accaagaatt tcttttgttt cagtattaac aacagctttg aaagctccgc
    40981 gaaggtctcc atttacgtga ccacgaggca tggctgcaac agggatttct ttcactgcgt
    41041 atggaagttt caaatcagct gcttggcttt cagtcaaacc aacttgtgaa agtgcaggtg
    41101 tgatgaacat agtatttggc acattgagac ggtcctcaag tgtgtagctg ccatctccag
    41161 caaggtagct gtaaacaaca cggaagtcat caagtgaaat gtaagtaaat tgaaggccac
    41221 cgttgacatc tccaactgca aagacaccag gaacgtttgt ttgacagtgt ttgtctactt
    41281 taatagcacc acgttcagtt agttcaatat ctgtattttc aagttgaagt ggttctacat
    41341 ttggtttgcg tccagttgcg tagagaaggg cgtcgaaacg gtaagtttcg tcttcagtta
    41401 cgacaagcac ttggtcacca tcgtttttga tttcagtagt atggatattt tgaagcaatt
    41461 caatgccatc ttcttccatg tattgtttag caagagctgc gatggaaggt tctgcacgag
    41521 gtaggaatgt atccaaggca tctaggactg tgaccttgct tccaagtttg ttgtaaaggc
    41581 cggcaaattc aagaccgata tttccgccac caaggattcc aagtttttca ggtaatttgt
    41641 ccaagctttg gatacctgtt gagtcaaaga tgtttttgct tgtagcaagt ccaggaattg
    41701 gcaagacgtt tgaaacagca ccagtgttga tgacgattgt ttcagcagtc agttctttct
    41761 tttcatcacc agcttggatt tcgatgactt tatttgaaag gaagtgagct tccgcatcaa
    41821 agatatctac gcctgtacca gcaacagtcg catagttttt accgttgagg cgaccagtga
    41881 tcgtgttttt agtagcaatc acttcttcaa aagacaagtc cttttcagca gcaactagca
    41941 aggttttagt tgggatacaa ccaatgttga tacaagttcc accgtacata gccttgctgc
    42001 gttcaacgag ggcaactttt ttgccagctg aagccaattt acctgctagt gttttaccag
    42061 ctttaccaaa tccaataaca attaaatcgt atgttaacat ttatcttcct cctattcgaa
    42121 tttcattcta gcacaagaaa aaaacttttg cacaattctg ctacggaaaa gacagaaaaa
    42181 gataaaaacg ctttccagac aaaaaactag taattttttg acaagcttga taaactaaaa
    42241 tcctatctat ttttatataa gaaagaataa atgttcgaaa ataggaggtt ttatgaaatc
    42301 gaatcgttat attattgcct ttgctggggt cattttacac ttaatgctgg gttcgactta
    42361 tgcttggagt gtttatcgta accctattat tgaaaaaacg ggatgggatc aggcttctgt
    42421 tgccttcgcc tttagtctag caatcttttg tttgggctta tcggctgcat ttatggggcg
    42481 tttggtagaa aaatttggtc cgaaagtcat ggggagtcta tctgcttttc tatacgcagg
    42541 tggaaatatc ttaacaggat ttgcaataga ccgtcaggaa ctgtggttgt tgtatctagc
    42601 ttatggcatt ttaggtgggc ttggtttggg agcaggctat attacccctg tgtcaacgat
    42661 tataaaatgg tttcctgata aacgtggtct cgcaacaggt ttagcgatta tggggtttgg
    42721 ttttgcttct ttattgacta gtcccatagc gcaacacctc atcgcagggg tagggattgt
    42781 agaaactttt tatattttag gagcaagtta ctttattatc atgctcctag cttcacaatt
    42841 cattaagcgt ccaaatgagc aagagcttgc aattttatct tcttcaggga aagaaaaaac
    42901 agcctctttg acgcaaggaa tggctgcaaa tcaggctcta aaaagcaatc ggttttatat
    42961 gctttggatt attttcttta tcaacatagc ttgtggttta ggcttaattt cagcggcatc
    43021 gccaatggca caggagatgg ctggcttgtc tacaagtcat gcagcagtaa tggtgggtgt
    43081 tttggggatt ttcaatggat ttggtcgctt gctctgggcg agtttgtctg actatatcgg
    43141 tcgccctcta acctttagta tattactgct tgtcaatctt ttcttttctc tctcactttg
    43201 gctctttaca gattccgttt tatttgtagt tgctatgtct attttgatga cttgctatgg
    43261 agctggtttt tctttgattc cagcttatct cagtgatatt tttggaacca aggaattggc
    43321 cgctctgcat ggttatattt taacagcttg ggcaatggct ggtttagcgg gacctatttt
    43381 attagcagag acttataaaa tggctcattc gtacacacaa accttgttcg tttttctcat
    43441 tttatacagt atcgccttgg ctttgtctta ttatctaggt cgttcaatca aaaaagaaag
    43501 tcaaaaaccg cttacatgat tttctgtaga aatggggcta tcttttgctc tggtcttgtg
    43561 ttatactaga taggttgcaa agaaaacagt acttttcttt tgtggaaaag aagcaacacg
    43621 attttatatc tagttatatg aaaatacgtc ataaaaagaa aagtataaac taagccctat
    43681 agggtggctt cgcaccacct ttagaaagaa gaataacgtg aaatttaatg aattaaactt
    43741 gtctgctgat ttgctagcag aaattgaaaa agctggtttt gtagaagcta gtcctatcca
    43801 agaacaaact attcctttgg cccttgaagg caaggatgtt atcggtcaag ctcagactgg
    43861 tacaggaaaa actgcagcct ttggcttgcc tacccttgaa aaaatccgta tagaagaagc
    43921 gactattcaa gccttggtca tcgctccaac tcgtgaacta gctgtccaaa gtcaagaaga
    43981 actcttccgc tttggtcgta gtaagggagt caaagtccgt tcagtatatg gcggatcaag
    44041 cattgaaaaa caaattaagg ctcttaaatc tggtgcccat atcgtggtgg gaactccagg
    44101 tcgcctcttg gacttgatta aacgcaaggc cttgaaatta caagacattg aaacccttat
    44161 ccttgacgaa gcggatgaaa tgcttaacat gggcttcctt gaagacatcg aagccattat
    44221 ttcccgtgta cctgagaacc gtcaaacttt gcttttctca gcaactatgc cagatgccat
    44281 caaacgtatc ggtgttcagt ttatgaaagc ccctgaacat gtcaagattg cggctaagga
    44341 attgacaaca gaattggttg accagtacta tatccgtgtt aaggaacaag aaaaatttga
    44401 caccatgact cgtctcatgg atgtggcaca accagaactc gctattgtat ttggtcgtac
    44461 caaacgccgt gtggatgaat tgactcgtgg tttgaaaatt cgtggcttcc gtgcagaagg
    44521 aattcatggc gacctagacc aaaacaaacg tcttcgtgtc cttcgtgact ttaaaaatgg
    44581 caatcttgat gttttggttg cgacagacgt tgcagcgcgt ggtttggata tttcaggtgt
    44641 gacccatgtc tacaactacg atattccaca agatcctgag agttatgttc accgtatcgg
    44701 tcgtacaggt cgtgctggta agtcaggtca atctattact tttgttgctc caaacgaaat
    44761 gggttacctt caaatcattg aaaacttgac taagaaacgc atgaaaggtc tcaaaactgc
    44821 aagtgtagaa gaatccttcc aatcaaaaaa acaggtagct ctcaagaaaa tcgaacgtga
    44881 ttttgcagat gaaaccattc gtgccaactt tgagaaattt ggtaaggatg ctcgcaaatt
    44941 ggctgctgag tttactccag aagaattggc aatgtatatc ttgagtctga cagtccaaga
    45001 cccagatagc cttccagaag tggagattgc acgtgaaaaa ccactaccgt ttaaaccatc
    45061 aggtaatggt ttcggtggta aagctaaggg aggtcgtgga ggccgtcgtg gggacgaccg
    45121 tcgagagcgt gatcgtcgtg gcaatggtcg ccgtgatgag ttcaaaaaag gaagtcgtgg
    45181 caacgatcgt tttgataagg aaaaacgtta ccgtaaggat aataaaaaac cacgcaatac
    45241 tttaagcgaa aagcaaacag gctttgttat tcgtaacaaa ggtgataaat aagaaaaagc
    45301 ggttcaaaat gaatcgcttt tttatataag gagaccgaat gtgaaaaaga caaataaaat
    45361 tattatatta tcttttataa tattatgata cacaaaaata ggcgacttgt caatagaaaa
    45421 ggaacaattt aattaaaaat attctggttt ttaattaaat tgtaagtcaa tgcaagtcaa
    45481 taaggaattt tcagataatt attgaaaaag agacgttttt atgttataat gatagcgatt
    45541 aaattcgagg tgaaaaatgg cacatttatt agaaaaaact agaaaaatta catcaatttt
    45601 gaaacgctca gaggagcagt tgcaggatga gctcccttac aacgctatta cgcgtcagtt
    45661 agcggatatt attcattgca atgcctgcat tatcaatagt aagggacgtc tgcttggcta
    45721 ttttatgcgt tataaaacaa atacagatcg cgtagagcaa ttcttccaaa ctaagatttt
    45781 cccagatgac tacgttcaag gggctaatat gatttacgaa acagaagcaa acttgcctgt
    45841 tgagcatgat atgagtattt tccctgttga gagtagagat gattttccag atggcttgac
    45901 gactattgca ccgattcatg tatcggggat tcgccttggt tctttgatta tttggcgtaa
    45961 tgataaaaaa ttcgaagatg aggacttggt tcttgttgag attgccagta ccgttgttgg
    46021 gattcagctt cttaacttcc aacgtgaaga agatgagaaa aatattcgtc gtcgtactgc
    46081 tgtcaccatg gcggtcaata ccctttctta ctccgaactc cgtgctgttt cagcaatttt
    46141 aggggaatta aatggaaatg aagggaagtt gactgcgtca gtgattgcag atcgtatcgg
    46201 aatcactcgc tctgtgattg tcaatgctct tcgtaaactt gagtctgcgg ggattattga
    46261 aagtcgctca cttggaatga agggaaccta tcttaaggtc ttgatttcag atatttttga
    46321 agaagtgaag aaaagagatt actaatgaca aaggctttaa tttcgattga ttatacagaa
    46381 gattttgttg ctgatagtgg gaagctgaca gcaggtgctc cagctcaggc gatttcggat
    46441 gccatcagca aggtaactcg attagctttt gaacgaggag attatatctt ctttactatt
    46501 gatgctcatg aagaaaacga ttgtttccat ccggaaagta agttatttcc tcctcataat
    46561 ctgattggga cgagtggacg gaatttatat ggagatttgg ggatctttta tcaagagcat
    46621 ggttcagaca gtcgtgtctt ttggatggat aaacgccatt actcagcttt ttcagggact
    46681 gacctagata ttcgtttgag agagcgtaga gtgtctaccg ttatcttaac aggtgtcttg
    46741 acggatatct gtgtcctaca tacagctata gatgcctata atctaggata tgacatcgag
    46801 attgttaaac cagctgttgc ttccatctgg cctgaaaatc atcaatttgc cctaggtcat
    46861 ttcaaaaata cactcggagc taagttagta gatgaaaatc taaatgaact ttctgagtaa
    46921 cctggttggt gaaaatgaaa aaatttgaaa aaaagtgttg acaagcatcc caaaagttga
    46981 tatactagta aagtaatcga tgcggggatg gcggaattgg cagacgcgca ggactaagga
    47041 tcctgtgacc gctttaggtc gtgagggttc aagtccctct ctccgcatag gaaaagagtt
    47101 agctaaagct agctcttttg tatttctcta aaaaattaga atccagtcaa atgtagtgga
    47161 gaatcagcga aaatatggga aaactgatcc ttgtttctgc ttttgtcata gaagaataat
    47221 aaagattatc ttcttcaaat tctccgatat tctctaaagt tttgtgcaag ttgcacagaa
    47281 cttttttatt tttttggtca tcttgccata gaaatataaa gcgttttcat ctataatata
    47341 attatcaaaa gacaaaagga gttcacctca tggtagaatt gaatcttaaa aatatttaca
    47401 aaaaatatcc aaacagcgaa cactattcag ttgaagattt caacttgaac atcaaagata
    47461 aagaatttat cgttttcgta ggaccttcag gatgtggtaa atcaactaca ctccgtatga
    47521 ttgctggtct tgaagacatc acagaaggta ctgcatctat cgatggcgtg gttgtcaacg
    47581 acgtagctcc aaaagaccgt gatatcgcca tggtattcca aaactacgct ctttacccac
    47641 acatgactgt ttatgacaac atggctttcg gtttgaaatt gcgtaaatac agcaaagaag
    47701 acattaacaa acgtgttcaa gaagcagctg aaatacttgg attgaaagaa ttcttggaac
    47761 gtaaaccggc tgacctttca ggtggtcaac gtcaacgtgt tgccatgggg cgtgcgattg
    47821 tccgtgatgc gaaagtattc ttgatggacg aacctttgtc aaacttggat gccaaacttc
    47881 gtgtatcaat gcgtgctgaa atcgctaaaa ttcaccgtcg tatcggagct acaactatct
    47941 atgtaactca cgaccaaaca gaagcgatga cacttgcaga ccgtatcgtt attatgtcag
    48001 ctactaagaa ccctgctggt acaggtacta tcggacgtgt agaacaaatc ggtactcctc
    48061 aagaagttta caaaaatcca gttaacaaat tcgttgcagg attcatcgga agcccagcta
    48121 tgaacttcat caacgtgaaa ttggttggta gcgaaattgt ttctgacggt ttccgtttga
    48181 aagtgccaga aggagcattg aaagttcttc gtgaaaaagg ctacgaagga aaagaattga
    48241 tctttggtat ccgtccagaa gacgtgaatg cagaacctgc tttccttgaa acattcccag
    48301 actgtgttgt aaaagcgact atctctgtat cagaactgct tggttcagaa tctcaccttt
    48361 actgccaagt tggtaaagac gagtttgttg caaaagttga tgctcgtgac tacttgcaaa
    48421 caggtgcaac agttgagctt ggatttgact tgaacaaagc acacttcttc gatgtagaaa
    48481 ctgaaaaaac aatctactaa gaataaataa aattcaaagc actacaagaa aagatatctc
    48541 tttatcaatt gtagtggaga gatatcagtt aatctaggga gagaaacaaa atgcttctct
    48601 cctttttgct agggaagtca tattatacat ctatattgtg atgctcttta tactcttcga
    48661 aaatctcttc aaaccacgtc aacgtcgcct tgccgtacgt atgattactg acttcgtcag
    48721 ttttatctgc aacctcaaag ctgtactttg agtagcttac ggctagtttc ctagtttgct
    48781 ctttgatttc cattgagtat tatttgtggg taccatctac aagtgaagct atatgcgtaa
    48841 actacgtgag caattgaatt cgaactagag aggtaataat aaatttatgc tatagttatg
    48901 gtgacttgta tgcttttgat tctagtttat caaataatag attagaattg tcagataata
    48961 tcattttgtg tcattttgtg ttataatgaa gaaaaaacag aggtgttcaa atgtcagaag
    49021 caggtcataa gtttttagca aaattgggga aaaaacgctt acgtccaggt ggaaagcgtg
    49081 ccacagattg gttaattgca gaaggaggat tttcaaaaga aaagagaata ctagaggttg
    49141 cgtgtaatag gggaactaca gcaattgagt tggcacagcg ttttggttgc aagataactg
    49201 ctgttgatat ggatgctcaa gctttagaag tggctaaaaa atctgctgga acggcaggtg
    49261 ttgctcattt aatcagtttt gaaagagcaa atgcaatgaa acttccttat caagatgcta
    49321 gttttgatat tgttataaat gaagctatgc tgactatgca agccgatcaa gctaagaaaa
    49381 aatgtgtaat ggaatatcta agggtattaa aacctggagg tcttctcttg acacatgatg
    49441 tgcttcttaa ggaagctaaa gagtctatca gacaggaatt atcacaagca attcatgtaa
    49501 atgtaggtcc tttaactcaa gatggttggg aacaggtgat gatagaatca ggttattgtg
    49561 atgtgaaagt attgactggt gaaatgacat taatgaaatt atcgggtatg atttatgacg
    49621 aaggttggct aggaactttg aaaatttgtg taaatgcttg taaaaaggag aatagaaagc
    49681 agtttttaac tatgtataaa atgtttgcta agaataaaca gaaattgggc tttattgcga
    49741 tggctagtta taaatcgtca aaacgttaga taattattga agttaacttt tccttttttc
    49801 tttcttaaaa aatatgctat aatagagagt aaaaaacttt gaaagaaaga aaaagatgaa
    49861 tttaaaagat tacattgcaa caattgaaaa ttatccaaag gaaggcatta ccttccgtga
    49921 tattagtcct ttgatggctg atggaaatgc ttatagctac gctgttcgtg aaatcgttca
    49981 gtatgctact gacaagaaag tcgacatgat cgtgggacct gaagctcgtg gatttatcgt
    50041 gggttgtcca gttgcctttg agttgggaat tggttttgcg cctgttcgta agccaggtaa
    50101 attgccacgc gaagttattt ctgctgacta tgaaaaagag tacggtgtcg ataccttgac
    50161 tatgcacgcg gatgccatta agccaggtca acgtgttctt attgtagatg accttttggc
    50221 gacaggtgga actgttaagg caactatcga gatgattgaa aaacttggtg gtgttatggc
    50281 aggttgtgcc ttccttgttg aattggatga attgaacggc cgtgaaaaaa ttggtgacta
    50341 cgattacaaa gttcttatgc attattaatg aaaacagtcc ctagggctgt tttctctaca
    50401 ctaggatata aaaatagact ataactagtt agagaaaaac tataattgaa aactatatct
    50461 tcttacagta taataaaagg actaagtgtt tgagatttgt cttcaaacat atgcaattat
    50521 tcctgaaaga gtacagttag gagagggtta tgccgattcg aattgataaa aaattgccag
    50581 ctgttgagat tttacggaca gagaatatct ttgtcatgga tgatcaacgt gctgcccacc
    50641 aagatatccg tcctttgaag attttaattt taaatctcat gccacagaaa atggtcacag
    50701 agacccagtt gttgcgccac ttggctaata cacccctaca actggatatt gattttctct
    50761 atatggagag ccaccgttct aaaacaactc gttcagagca catggagacc ttctataaaa
    50821 cttttcctga agtcaaggat gagtattttg atgggatgat catcacgggt gctccagttg
    50881 agcatttacc atttgaggaa gtggactatt gggaggaatt tagacagatg cttgagtggt
    50941 ctaagactca tgtctattcg acccttcata tctgttgggg ggctcaggct gggctttatc
    51001 tgcgctatgg tgtagaaaaa taccagatgg acagtaagct atcaggtatt tatcctcagg
    51061 acaccctaaa agagggtcac cttctattta gaggctttga tgatagctat gtatcccctc
    51121 attcacggca cacggagatt tctaaggaag aggtcttaaa caagaccaat ctcgagattt
    51181 tatcagaagg acctcaggtt ggggtttcta ttttggccag tcgtgattta cgagaaattt
    51241 atagttttgg tcatttggag tatgaccgtg ataccttggc aaaagagtat tttcgagatc
    51301 gtgatgcagg tttcgaccca catattccag aaaattactt taaagatgat gatgttaatc
    51361 aggtaccttg tctttgttgg tcttcatctg cagccctctt tttcagtaat tgggtaaacc
    51421 atgcggtcta tcaggagacg ccttttgact ggagaaagat agaagatgat gcatctgcat
    51481 ataggtattt ataagaggaa ttatgacata tttagacgct tttaaatcag gtaccttggt
    51541 tttaccgagt gccctgctct tgcattttaa ggaactcttt ccttctagcg acgattttct
    51601 ggtttggcaa tttttctatt tgcaaaatac gacaggctta gaagaaatat cgccaagcca
    51661 gattgctgaa aggattggca aggaaatttc ggatgtcaac cagtccattt ctaatctgac
    51721 ggaaagggga ctgctccagt atcgtactat cgaattaaat ggcgaaattg aattgctctt
    51781 tgatgctagt ttggccttgg aacgtttgga tgacctgttt ggagcagttc attcaagttc
    51841 agaccagcta acaccacaaa accagctcaa ggatttggtg gaaaccttcc agcaggagtt
    51901 gggacgattg ttgacgcctt ttgagattga ggatttgacc aagacactaa aggaagatgg
    51961 aaccagtgct gacttgatta aggaggctct tcgtgaagct gttttgaacg gaaaaccaaa
    52021 ctggaagtac attcaggcga ttttgagaaa ctggcgccat gaaggaatca agagtgtggc
    52081 tcaaattgag gccaagagag cagaaagaga agcaagcaat cctcagttga cacaggtatc
    52141 tgcagatttc ataaatgcca tggatctctg gaaggattaa tccatgcaag taggcttgaa
    52201 atccgagtaa gatttgcaag ctgtgtataa ttgtgataga ataaatagaa aataaattga
    52261 aaaaagaggt atgtgaaatg tcacgtaaac catttatcgc tggtaactgg aaaatgaaca
    52321 aaaatccaga agaagctaaa gcattcgttg aagcagttgc atcaaaactt ccttcatcag
    52381 atcttgttga agcaggtatc gctgctccag ctcttgattt gacaactgtt cttgctgttg
    52441 caaaaggctc aaaccttaaa gttgctgctc aaaactgcta ctttgaaaat gcaggtgctt
    52501 tcactggtga aactagccca caagttttga aagaaatcgg tactgactac gttgttatcg
    52561 gtcactcaga acgccgtgac tacttccatg aaactgatga agatatcaac aaaaaagcaa
    52621 aagcaatctt tgcgaacggt atgcttccaa tcatctgttg tggcgaatca cttgaaactt
    52681 acgaagctgg taaagctgct gaattcgtag gtgctcaagt atctgctgca ttggctggat
    52741 tgactgctga acaagttgct gcctcagtta tcgcttatga gccaatctgg gctatcggta
    52801 ctggtaaatc agcttcacaa gatgatgcac aaaaaatgtg taaagttgtt cgtgacgttg
    52861 tagctgctga ctttggtcaa gaagtcgcag acaaagttcg tgttcaatac ggtggttctg
    52921 ttaaacctga aaatgttgct tcatacatgg cttgcccaga cgttgacggt gcccttgtag
    52981 gtggtgcgtc acttgaagct gaaagcttct tggctttgct tgactttgta aaataatcag
    53041 taagtagcaa aagctaggtg gaacagcatt cagatgtctg ttacattttt tataggagag
    53101 gaaagattga aaacaaaaat tggattagca agtatctgtt tactaggctt ggcaactagt
    53161 catgtcgctg caaatgaaac tgaagtagca aaaacttcgc aggatacaac gacagcttca
    53221 agtagttcag agcaaaatca gtcttctaat aaaacgcaaa cgagcacaga agtacagact
    53281 aatgctgctg cccactggta tggggattat tatgtaaagg atgatggctc taaagctcaa
    53341 agtgaatgga tttttgacaa ctactataag gcctggtttt atattaattc agatggtcgc
    53401 tactcgcaga atgaatggca tggaaattac tacctgaaat caggtggata tatggcccaa
    53461 aacgagtgga tctatgacag taattacaag agttggtttt atctcaagtc agatggggct
    53521 tatgctcatc aagaatggca attgattgga aataagtggt actacttcaa gaagtggggt
    53581 tacatggcta aaagccaatg gcaaggaagt tatttcttga atggtcaagg agctatgatg
    53641 caaaatgaat ggctctatga tccagcctat tctgcttatt tttatctaaa atccgatgga
    53701 acttatgcta accaagagtg gcaaaaagtg ggcggcaaat ggtactattt caagaagtgg
    53761 ggctatatgg ctcggaatga gtggcaaggc aactactatt tgactggaag tggtgctatg
    53821 gcgactgacg aagtgattat ggatggtgct cgctatatct ttgcggcctc tggtgagctc
    53881 aaagaaaaga aagatttgaa tgtcggctgg gttcacagag atggtaaacg ctatttcttt
    53941 aataatagag aagaacaagt gggaaccgaa catgctaaga aaatcattga tattagtgag
    54001 cacaatggtc gtatcaatga ttggaaaaag gttattgatg agaacgaggt ggatggtgtc
    54061 attgttcgtc taggttatag cggtaaagaa gacaaggaat tggcgcataa cattaaggag
    54121 ttaaaccgtc tgggaattcc ttatggtgtc tatctctata cctatgctga aaatgagacc
    54181 gatgctgaga atgacgctaa acagaccatt gaacttataa agaaatacaa tatgaacctg
    54241 tcttacccta tctattatga tgttgagaac tgggaatatg taaataagag caagagagct
    54301 ccaagtgata cagacacttg ggttaaaatc atcaacaagt acatggacac gatgaagcag
    54361 gcgggttatc aaaatgtgta tgtctatagc tatcgtagtt tattacagac gcgtttaaaa
    54421 cacccagata ttttaaaaca tgtaaactgg gtagcggcct atacgaatgc tttagaatgg
    54481 gaaaaccctt attattcagg agaaaaaggt tggcaatata cctcttctga atacatgaaa
    54541 ggaatccaag ggcgcgtaga tgtcagcgtt tggtattaag cgatgatttg aaagagggat
    54601 gtgatagtag caccctcttt ttctttgttt tatgatagtt catcctcgag taaattcaag
    54661 atcttgcttg gaaatgaagc ttatatagta gattgaatat agacaaatac cttgtgattg
    54721 gtaaaacatt ttagaaattc atttaccttt cctaatcgac ttggtttcat cttatttcaa
    54781 tctattatag tattggggaa tttcttcaaa ccacatcagc ttggtcagtt ctacctgcga
    54841 cctcaaaact tgtgctttgg tcaaactggg tttagtttcc tagtttgctg atggatttcc
    54901 attgactata agcatccaac cctctttttg tcttctaaag aattcttaaa ttatcagtct
    54961 attgcaactt ttctcatata agttctttgt cttgctattg gttttcctta gtagtatact
    55021 aaggtagtaa tcattaagaa gtggttacaa aaaataatga atgaggtaaa gaaaatggta
    55081 gaattgaaaa aagaagcagt aaaagacgta acatcattga caaaagcagc gccagtagca
    55141 ttggcaaaaa caaaggaagt cttgaaccaa gctgttgctg atttgtatgt agctcacgtt
    55201 gctttgcacc aagtgcactg gtatatgcat ggtcgtggtt tccttgtatg gcatccaaaa
    55261 atggatgagt acatggaagc tcttgacggt caattggatg aaatcagtga acgcttgatt
    55321 acactcggtg gaagcccatt ctctacattg acagagttcc ttcaaaatag tgaaatcgaa
    55381 gaagaagctg gtgaataccg taatgttgaa gaaagcttgg aacgtgttct tgttatctac
    55441 cgttacttgt cagaactttt ccaaaaaggt ttggatgtca ctgatgaaga aggtgacgat
    55501 gtgacaaacg gtatctttgc aggcgctaaa actgaaacag ataaaacaat ttggatgctt
    55561 gcagccgaac ttggacaagc acctggtttg taagaaataa ggaaacatag ataaatctgt
    55621 aggaaatttc ttacagattt tttctatttt gtaagctatt ccaaaccagt ctttttttga
    55681 gttttttgat aaaatagtac tatcagtgaa aaggatggaa gcatgactaa gaaaatcgta
    55741 gctatttggg cccaggataa agagggtgtg attggtaagg aaaatcgtct gccttggcat
    55801 ttgccagcag aattgcagca ctttaaagaa acaactctga atcatgctat cttgatgggg
    55861 cgtgtgacct ttgatgggat ggggcgtcgc ttgcttccaa aacgggaaac cctgattttg
    55921 acgcgtaatc cggaagaaaa gatagatggg gttgctactt ttcaggacgt ccagtctgtt
    55981 cttgattggt atcaggctca agaaaagaat ctctacatta tcggtgggaa gcaaattttt
    56041 caggcttttg aagcttacct tgatgaagtg attgtcactc acattcatgc tcgggtggaa
    56101 ggagatacct atttccctgg agagcttgac ttgtctcttt ttgagacagt ttcaagcaaa
    56161 ttttacgcca aagatgagaa gaatccttat gattttacca tccaataccg caagagaaag
    56221 gaagtctaat ggaacggagt ttatttggtc tattcacggc ttttctgtgt ttcatctgct
    56281 ttctggcagg agcacaagct tttcgtaaaa agcgttacgg gctttctatc ctcctttggt
    56341 taaatgcctt taccaatctg gtcaatagta ttcatgcttt ttacatgacc ttattttaga
    56401 tagaatgaca gtatagaatg gaaggaaatc atgtctacaa atagaaaaaa tgatatgatg
    56461 gtttattgct cattttgtgg caaaaaccaa gaagaagtac aaaaaataat tgctggcaac
    56521 aatgctttta tttgtaatga atgcgtggag ttagctcagg aaatcattcg agaagaattg
    56581 gttgaggaag tcttggcaga cttgtctgag gtgccaaaac caattgaact cctccatatc
    56641 ttgaaccact atgtaattgg tcaagatcgt gccaagcgtg ccttggcagt ggcggtttat
    56701 aatcactaca aacgcatcaa tttccacgat acacgcgaag agtcagaaga tgtggatttg
    56761 cagaagtcaa acattttgat gattggccca actggttcag ggaaaacttt ccttgcccag
    56821 accttggcta agagcttgaa tgtgcctttt gctattgcgg atgcgacagc tctgacggag
    56881 gctggttatg tgggtgagga tgtggaaaat atcctcctca aactcttgca ggttgctgac
    56941 tttaacatcg aacgtgcaga gcgtggcatt atctatgtgg atgaaattga caagattgcc
    57001 aagaagagtg agaatgtgtc tatcacacgt gatgtttctg gtgaaggggt gcaacaagcc
    57061 cttctcaaga ttatcgaggg aactgttgct agcgtgccgc ctcaaggtgg acgcaaacat
    57121 ccacaacaag agatgattca agtggataca aaaaatatcc tcttcatcgt gggtggtgct
    57181 tttgatggta ttgaagaaat tgtcaaacaa cgtctgggtg aaaaagtcat cggatttggt
    57241 caaaacaata aggcgattga cgaaaacagc tcatacatgc aagaaatcat cgctgaagac
    57301 attcaaaaat ttggtattat ccctgagttg attggacgct tgcctgtttt tgcggctctt
    57361 gagcaattga ccgttgatga cttggttcgc atcttgaaag agccaagaaa tgccttggtg
    57421 aaacaatacc aaaccttgct ttcttatgat gatgttgagt tggaatttga cgacgaagcc
    57481 cttcaagaga ttgctaataa agcaatcgaa cggaagacag gggcgcgtgg acttcgctcc
    57541 attatcgaag aaaccatgct agatgttatg tttgaggtgc cgagtcagga aaatgtgaaa
    57601 ttggttcgca tcactaaaga aactgttgat ggaacggata aaccgatcct agaaacagcc
    57661 tagaggtgac tatggaactt aatacacaca atgctgaaat cttgctcagt gcagctaata
    57721 aatcccacta tccgcaggat gaactgccag agattgccct agcagggcgt tcaaatgttg
    57781 gtaaatccag ctttatcaac actatgttga accgtaagaa tctcgcccgt acatcaggaa
    57841 aacctggtaa aacccagctc ctgaactttt ttaacattga tgacaagatg cgctttgtgg
    57901 atgtgcctgg ttatggctat gctcgtgttt ctaaaaagga acgtgaaaag tgggggtgca
    57961 tgattgagga gtacttaacg actcgggaaa atctccgtgc ggttgtcagt ctagttgacc
    58021 ttcgtcatga cccgtcagca gatgatgtgc agatgtacga atttctcaag tattatgaga
    58081 ttccagtcat cattgtggcg accaaggcgg acaagattcc tcgtggtaaa tggaacaagc
    58141 atgaatcagc aatcaaaaag aaattaaact ttgacccaag tgacgatttc atcctctttt
    58201 catctgtcag caaggcaggg atggatgagg cttgggatgc aatcttagaa aaattgtgag
    58261 gaaaagaaaa tggcaaaaac aattcataca gataaggccc caaaggctat cgggccctat
    58321 gttcaaggaa aaatcgttgg caaccttttg tttgctagcg gtcaagttcc cctatcccct
    58381 gaaactgggg aaattgtagg agagaatatc caagaacaga cagagcaagt cttgaaaaac
    58441 atcggtgcta ttttggcaga agcaggaaca gactttgacc atgttgtcaa aacaacttgt
    58501 ttcttgagcg atatgaacga ctttgttcct tttaatgagg tttaccaaac ggccttcaaa
    58561 gaggaattcc cagctcgttc agctgtggag gtagctcgtc ttcctcgtga tgtaaaagtc
    58621 gaaattgaag tcatcgcaga gattggataa gctagttgaa gtttggtgtt gccaaacttc
    58681 ttttgatata aggagaaaaa gatgacaaag aaacaacttc acttggtgat tgtgacaggg
    58741 atgagtggcg cagggaaaac tgtagccatt cagtccttcg aggatctagg ttatttcacc
    58801 attgataata tgccgccagc tctcttgcct aagtttttgc agctggttga aattaaggaa
    58861 gacaatccta agttggcctt ggtagtggat atgcgtagcc gttctttctt ttcagagatt
    58921 caagctgttt tggatgagtt ggaaaatcaa gatggtttgg atttcaaaat cctctttttg
    58981 gatgcggctg ataaggaatt ggtcgctcgt tacaaggaaa ccagacggag tcacccacta
    59041 gcagcagacg gtcgtatttt agatggaatc aagttggaac gtgaactctt ggcacctttg
    59101 aaaaatatga gccaaaatgt ggtggatacg actgaactca ctccacgtga gctgcgcaaa
    59161 acccttgcag agcagttttc agaccaagaa caagcccagt ctttccgtat cgaagtcatg
    59221 tctttcggat ttaagtatgg aatcccgatt gatgcggact tggtctttga tgtccgtttc
    59281 ttgccaaatc cctattattt accagaactg agaaaccaaa cgggtgtgga tgaacctgtt
    59341 tatgattatg tcatgaacca tcctgagtca gaagactttt atcaacattt attggccttg
    59401 attgagccga ttctgccaag ttaccaaaag gaaggtaagt ccgttttgac cattgccatg
    59461 ggatgtacgg gtggacaaca ccgtagtgtg gcatttgcta aatgcttggc gcaggactta
    59521 tccaagaatt ggtctgttaa tgaagggcat cgcgacaaag accgcagaaa ggaaacggta
    59581 aaccgttcat gagaaaacca aagataacgg tgattggtgg agggactgga attcccgtca
    59641 ttctaaaaag tctgcgggaa aaagatgtgg aaatcgcagc tatcgtgacg gtggcagatg
    59701 atggtggttc ttcaggtgaa ctccgaaaaa atatgcaaca gttgacaccg ccaggtgatc
    59761 ttcgtaatgt ccttgtggcc atgtcggata tgcctaagtt ttatgagaag gtctttcagt
    59821 atcggttctc tgaggatgcc ggagcctttg ctggccatcc attgggaaat ctcatcattg
    59881 ctggcttgtc agaaatgcag ggttcaacct ataatgccat gcagttattg agcaaatttt
    59941 tccatacaac agggaaaatt tatccttcca gtgaccatcc tttgaccctt catgcagtct
    60001 ttcaggatgg gacagaagtg gctggagaga gtcatattgt agaccatcga ggcataattg
    60061 acaatgtcta tgtgaccaat gccctaaacg atgatacgcc tctggccagc cgtcgagtag
    60121 tgcagaccat ccttgaaagt gacatgattg tcctagggcc aggttccctc tttacctcta
    60181 ttttgcccaa tatcgtgatt aaggaaattg ggcgggctct tttggaaact aaggcagaaa
    60241 ttgcctatgt ctgcaatatc atgacccaac gtggggagac ggaacacttt acagatagcg
    60301 accacgtgga agtcttgcat cgtcaccttg gtcgcccttt tatcgacact gtcttggtga
    60361 atattgaaaa agtgcctcag gaatacatga attccaaccg ttttgatgaa tacttagtgc
    60421 aagtggaaca cgattttgta ggtctttgta agcaagtttc gcgcgtgatt tcatctaact
    60481 tccttcgtct ggaaaatggc ggtgccttcc acgatggaga tttgattgtg gacgagttga
    60541 tgcgcattat acaggtgaaa aaatgagttt cacagtagca gtaaaagaag aaatcctggg
    60601 ccaacaccac ctgagccggc atgaattatc tgccattatc aaaatgtctg gtagcatcgg
    60661 tctctcgact tcgggcttga ctttgtcagt tgtgacagaa aatgccaaac tggcccgtca
    60721 cctctatgag tcctttctcc atttctatga aatcaaatct gaaattcgtc actaccaacg
    60781 gagcaatctt cgcaagaatc gcgtctatac cgtttttaca gatgaaaagg tgcaggattt
    60841 gttaagtgat ttgcacttgg cagactcttt ctttggcctg gaaacaggta ttgatgaggc
    60901 gattttatcg gacgaggaag caggtcgtgc ctatctctgt ggcgctttct tggcaaatgg
    60961 gagcattcgt gaccctgagt caggcaagta ccagttggaa atcagttctg tttatctgga
    61021 ccacgcgcaa ggaattgcct cccttctcca acagttttta ctggatgcca aggtgcttga
    61081 gcgcaagaag ggggctgtga cctatctcca gcgagcagaa gacattatgg acttcttgat
    61141 agtaatcgga gccatgcagg cacgtgatga ttttgagcgg gttaagattt tgcgagaaac
    61201 ccgtaacgac ctcaatcggg ctaataatgc cgagacagct aatatcgctc ggacagtttc
    61261 tgccagcatg aagaccatta acaatatcag taaaatcaaa gatatcatgg gcttagaaaa
    61321 tttgccagta gatttgcagg aagtggcgca actgaggatt cagcacccag actactctat
    61381 ccagcagtta gcagatagtc tcagcacccc tctgaccaaa agtggtgtca atcacagact
    61441 cagaaaaatc aataagatag cggatgaatt ataaaaccac gaatcctatg tgactcgtgg
    61501 ttctttttta taaactagta gagtgttttg gttgtacttt ttgttcaggg tcaatgtagt
    61561 tgatagcgtt gttgacagca gttggagctt ctccgaggcc tgtcgcaatc agatcaattt
    61621 ttccgtcata gtagcagcag tcaccgatag catagatacc tgcttggctg gattcctgtt
    61681 tgctgttgac gataatcttg tgacggttga ggtcgagccc ccagttttta aggttaccga
    61741 cagaagattt gaaaccatag ttgacaaaga ggtggtctag gtcaatggtt tcagtttcat
    61801 cagatttgac ttttgtgatt tcaagtttat caagtgtttt tccatttcca aggagttggc
    61861 taggggcgaa tggtgtcttg atggttacag atgattcttg caaggcttga acactgtgtt
    61921 ccaaggcacg gaaattatct ctgcggtgaa caagggtagt tggtgcgatt ttttcaaaag
    61981 ccaaagccca atccacagcc gagtctcccc caccaagaat cgtcactttc ttaccagcgt
    62041 attgctgaat gttagaaacg tggtagtgga tattttcata gccctcaacc ccttcaagtt
    62101 ccagcggacg tggtttgaag gcaccgccac ccatagcgat gataactgtt ttagtcaggt
    62161 gacttccttt agaagttgtg atggcaaatt cttcttgttt gtcaatctca agaaccgttt
    62221 cattgagatg aataggggta tcaaatccat ttagctgttc aatcaagcgg ttagtcaact
    62281 cttctccagt caggtttggg aagcctggta cgtctaggat ttccttttca gggtagagaa
    62341 tagcaggttg tccacctagc tggggaagag agtcgatgat ttgaaccttg gcttggcgta
    62401 ggtgggcata aaaggctgca aaaagcccga caggaccacc acccacaatg gtaatatcat
    62461 agagttgaga catagtttct cctttgtttt ttctagtcag tttattttat catatttttg
    62521 ttcaatgtaa aatggactag gatagggaaa aaaatgccag aaaatggtat aataggacga
    62581 aagtgttttg atagggagga tatcagggat gaattttcaa caattatcca atctgcaata
    62641 ttggaccagt ttgtttgcaa gtccatggac gatagctatc aatctgattg atattttgat
    62701 tgttgcttat attttatacc attttacaaa agctattgca ggaaccaaga ttatgatttt
    62761 ggtacgtgga gttttggtgt ttattttagc tcaaatcctt gcaaatatga ttggtttgac
    62821 tacgatttct tggttaatca atcaaattat tacttatggg gttattgcgg cggttgttat
    62881 cttctctcca gagattcgga ctggtttgga acgtttggga agagcgacag attttttttc
    62941 caatgcccct attagtgctg aggaacagat gattcgtgcc tttgttaagt ctgttgaata
    63001 catgagtcct cgtaaaatcg gggccttggt tgctattcag cgtgtacgta ccttgcagga
    63061 gtatatttcg acaggaattc ccttggatgc taagatttct gcagaacttc tcattaacat
    63121 ttttattccc aacactcccc tacatgatgg tgcggtgatt atcaaagaag aacgtatcgc
    63181 tgtgacgtct gcctatctgc ccttgacaaa aaacacaggg atttccaagg aatttgggac
    63241 cagacaccgg gcggctatcg gtttatcaga agtctcagat gccttgactt ttgtcgtatc
    63301 agaggaaacg ggaggaattt cgataaccta taatggaagg tttaagcaca acctaacact
    63361 tgatgaattt gaaacagaat tacgtgaaat cttacttcca aaagaggaag tgggtcttag
    63421 ttttaaagaa cgattgctag gaggatggaa acatgaaaaa aaatagttta tatatcatat
    63481 cctcactctt ttttgcttgt gtcttatttg tctatgctac ggcgacgaat tttcaaaaca
    63541 gtaccagtgc taggcaggta aaaacggaaa cctatactaa tacagtaaca aatgtcccta
    63601 ttgacatacg ctataatagt gataagtatt ttattagcgg ttttgcttca gaagtatcag
    63661 tggtcttgac tggggcaaat cgcctatcgc tagctagtga aatgcaagaa agtacacgta
    63721 aattcaaggt tactgctgac ctaacagatg ccggtgttgg aacgattgaa gttcctttga
    63781 gcattgaaga tttacccaat gggctgaccg ctgtagcgac tccgcaaaaa attacagtca
    63841 agattggtaa gaaggctcag aaggataagg taaagattgt accagagatt gaccctagtc
    63901 aaattgatag tcgggtacaa attgaaaatg tcatggtgtc agataaagaa gtgtctatta
    63961 cgagtgacca agagacattg gatagaattg ataagattat cgctgtcttg ccaactagcg
    64021 aacgcataac aggtaattac agtggttcag tacctttgca ggcaatcgac cgcaatggtg
    64081 ttgtcttacc ggcagttatc actccgtttg atacaataat gaaggtgact acaaaaccag
    64141 tagcaccaag ttcaagcaca tcaaattcaa gtacaagcag ttcatcggag acatcttcgt
    64201 caacgaaagc aactagttca aaaacgaatt aaaaatagaa aaggatttta taacaatggg
    64261 taaatatttt gggactgatg gagtccgtgg agaagctaac ctagaactaa caccagaatt
    64321 agcctttaaa ctaggacgtt ttggaggcta tgttcttagt caacatgaaa cggaagcgcc
    64381 gaaagtcttt gtaggacgtg acacacgtat ttcaggggaa atgctggaat cggccttggt
    64441 ggcaggtctc ctttcagtag ggattcacgt atacaaactt ggtgtccttg caacaccagc
    64501 agtagcttac ttggttgaaa ctgaaggagc aagtgccggt gtcatgattt ctgctagcca
    64561 caacccagcc cttgataacg gaatcaagtt ctttggcggt gatggcttca aactagatga
    64621 tgaaaaagaa gcagaaattg aagccttgct agatgctgag gaagacactc ttcctcgtcc
    64681 aagtgcagaa ggcttaggaa ttttggtaga ttatccagaa ggcttgcgta agtatgaagg
    64741 ataccttgtt tcaactggaa ctcctcttga tggaatgaag gttgccttgg atacagctaa
    64801 tggagcagct tctaccagtg cccgtcaaat ctttgcagac cttggtgccc aattgacggt
    64861 tatcggggaa acaccagacg gtcttaacat caaccttaat gttggttcaa cacatccaga
    64921 agcccttcaa gaagtggtca aagaaagtgg gtcagctatt ggtttggcct ttgatggaga
    64981 cagtgaccgc ttgattgctg ttgatgagaa tggtgacatc gtcgatggtg acaagattat
    65041 gtacatcatc ggaaaatacc tttctgaaaa aggacaattg gctcaaaata caattgtgac
    65101 aactgttatg tctaaccttg gtttccacaa ggccttgaat cgcgaaggta ttaacaaggc
    65161 agttactgca gttggtgacc gctacgttgt tgaagaaatg agaaaatcag gctacaacct
    65221 tggtggtgaa cagtctggtc acgttatctt gatggattac aataccacag gtgatggtca
    65281 attatcagca gttcaattga ctaaaatcat gaaggaaact ggtaagagct tatcagagtt
    65341 ggcggcagaa gtaacgattt atccacaaaa attagttaat atccgagtgg aaaacgtcat
    65401 gaaggaaaag gccatggaag tgccagctat caaggccatc atcgagaaga tggaagaaga
    65461 aatggcgggg aacggccgta tccttgttcg tccaagtgga acagagcccc tcttgcgtgt
    65521 tatggcagaa gcgcctacaa cagaagaagt ggactactat gttgatacca tcacagatgt
    65581 agttcgtgct gaaattggga ttgactaaat cctagaaaac tagatgaaaa taaaaaatta
    65641 tggtacaata gcttataata ttgtagccga tggagaaaga catgaatctt aaacgtgaac
    65701 aagaatttgt tagtcagtat cattttgatg cgcgtaattt tgaatgggaa aatgaaaatg
    65761 gagctcctga aaccaaggtg gatgtgaatt tccaattgct ccaacatgac caagaaaatc
    65821 aagtgacttc cttgattgtc atcttgagct ttatgattgt atttgataag tttgtcatta
    65881 gtggaacaat ctcacaagta aaccatatcg atggccgtat tgtcaatgaa ccaagtgaat
    65941 tgaaccaaga agaggtggaa accttggctc gtccatgttt gaacatgctc aatcgtttga
    66001 cttacgaagt gactgaaatt gcattagact taccaggaat taatttggag ttctaatatg
    66061 aaattagctg ttttcacaga ttcctctgct tatctcagtg aagagacctt gcaaagagaa
    66121 gacttgtttg tcttggatat tcctgtcaat attgatggtg aggaatatgt cgaaggcatc
    66181 aatctgtctg ctgaggaatt ttaccaaaaa atggctcagg cttctgaatt gcctaagacc
    66241 agtcaaccaa gtattgccaa gttagatgag atcttaactt cgctcaaaga acaaggctat
    66301 acacatgcct tggggctttt cctatcttct ggaatttcag gtttttacca aaatatccag
    66361 tatatggtcg atgactatga gggcttaacc attgctttcc cagacacttt gattacaagt
    66421 gctcccctag gcatcatggt tgaaagcgtc tttaattggc gtgatcaggg cgatgatttt
    66481 gccagcattc aggataagct agccattcaa atcagccgta cgtcagcctt tatcatggta
    66541 gatgacttgg atcatttggt aaaaggtgga cgcctttcaa atggggctgc cattttgggc
    66601 aatttgctta gcattaagcc aatcctttat tttaacgatc aaggtgtgat tgaagtttac
    66661 gaaaaagttc gtactgaaaa gaaggccacc aaacgcttaa ttgaaattat caaggaaaca
    66721 acggcttcag gtcaataccg ggtcattgtc attcatggga atgatcctga aaaggctgaa
    66781 gaattgcgtc agcatttgct tgattttggc ttgggttcgg atgtttcact tgctacattt
    66841 ggtagtgtca ttggaacgca cctaggagca ggaagtattg ctctgggtta tattccagtg
    66901 atttagtagg cacttctagg ctagttaatc ttagcaattg aacacggact acctgcctct
    66961 tgaaaaaaga tgtctgtctt gcctttcgtg gaaagtcagt gccattccct atttttcatg
    67021 ggtggctaag atcctttgta ttttgataat tgaacacgcc tggaaccctg tgtgaaaaag
    67081 atagttcttc caaggagtag acacttcttg atcagaattc ctattttcac tttgtgttct
    67141 tacaggcttt gtatcttaga caggagtaga gatgagtatt cgagtaatta ttgccggttt
    67201 taagggaaag atgggtcaag ctgcttgcca gatggtcttg cctgattcag atttggactt
    67261 ggtagcagtt ttggatcctt ttgagtctga gtcagaatgg cagggtattc ctgttttcaa
    67321 ggataaggct gatttagctg gttttgaagc ggatgtctgg gtagacttta ctactccagc
    67381 tgttgcctac gaaaatacac gttttgctct tgaaaatggc tttgctccag tagttggaac
    67441 gactggtttc acgagtgaag aaattgcaga gttaaaagaa ttttctcgtg cccaagactt
    67501 gggtggcctg attgccccta actttgcctt gggtgctgtc ttactcatgc aatttgcgac
    67561 gcaggctgcc aaatatttcc caaatgtgga gattattgag ctccatcatg acaagaaaaa
    67621 ggatgctccg agtggaacag ccattaaaac agctgagttg atggcagagg ttcgagagtc
    67681 cattcagcaa ggcgcagcag atgaggaaga gctgattgct ggtgctcgtg gtgctgactt
    67741 tgatggtatg cgcatccact cagttcgttt gccaggtttg gtagcccatc aggaagtcat
    67801 ctttggcaat caaggagaag gattgaccct ccgtcatgac tcctatgatc gcatctcctt
    67861 catgacagga gtcaatttgg gaattaaaga agttgtcaag cgtcatgagc ttgtctatgg
    67921 attagaacac ttattatgag attaacgcaa atgccttctg aatttcagaa ggctttacca
    67981 gtattagaaa aaattaaaga agcaggcttt gaggcttatt ttgttggggg ctctgttcga
    68041 gatgcccttc tccatagccc tatccacgat gtggatattg cgacgtcttc ttatccagaa
    68101 gagaccaagc agatttttcc gcgaacagcc gatatcggaa tcgagcatgg aaccgtcttg
    68161 gtcttagatg gggatgagga gtatgaggta acaacctttc ggacagagga tgtctatgtg
    68221 gactatcgca gacccagtgc ggtttccttt gtgcgctcgc tagaagaaga cctcaaacgc
    68281 cgtgatttca cagtcaacgc ctttgccttg gatgagacag gagaaatcgt tgacttgttc
    68341 catggtttag aagatttgga aaagcaagtc ttgcgagcag ttggagtggc tagtgagcgt
    68401 ttcaacgaag atgctttacg gattatgcgt ggtttccgtt ttcaggctag tcttggtttt
    68461 gcacttgagc cagaaacatt taaagctatg aagaccttga cgccgctttt ggagaacatt
    68521 tctgtagagc gtaccttcgt cgagtttgat aaactcttgc tggctccatt ttggagaagg
    68581 ggcttggctt ccatgattga gagtcaagct tatgactatc tccctgatat ggcatctagc
    68641 cagaacaagc tcaacagact gtttgatttg gagactgatt ttacttttga atcctctgaa
    68701 caagcctggg cggctttact atgggctttg gagattgaaa atgcgcagtc atttttgaaa
    68761 tcttggaaga cctcacgcca gtttgccaag caagttcagg atttgctgat tattttggct
    68821 ctgcgtgaaa atggagaatt gagcaagcga gattgttatc gctttgacat agatttgctt
    68881 ttacaggctg aaaatcttcg tcaagctcga ggaaaagaag tcaacccaca agccatcaca
    68941 gaaaaatacc aaagcttgac tatccatgac aagaaagaga ttcagattaa tggcgatatt
    69001 ttgatcaagg aatatggcta tcagccaggc ccagacttgg gagagatttt aacagagatt
    69061 gagtttgcca ttgtcgatgg agaattggag aataatcgtg aagccatcca tgcttacctg
    69121 agggagaaaa aatgagtgat tttatcgttg aaaaactaag taaatccgtt ggtgacaaga
    69181 ccgtttttag ggatatttcc tttattatcc atgacttaga cagaattggt ttaatcggtg
    69241 tcaatgggac tggcaagacc acccttttgg acgtcctttc tggtgtttct ggctttgatg
    69301 gggatgtcag tcctttttca gctaaaaatg attaccagat tggttacttg actcaggatc
    69361 ctgattttga tgatagaaag acagttttgg atacggttct atctagtgaa ctcaaggaaa
    69421 tccagctcat tcgtgagtat gaattgatta tgctcgacta tagtgaggac aagcaggcgc
    69481 gtttggaacg tgtcatggca gagatggact ctctccaagc ttgggaaatc gagagtcagg
    69541 tcaagaccgt tcttagcaaa ttgggcattc aagacttatc tactcctgtt ggggaattgt
    69601 caggtggtct gagaagacgg gtacagttgg cacaagtctt acttggcaac cacgacctct
    69661 tgcttttgga tgagccgacc aaccatctgg atattgcgat tattgagtgg ctgaccctct
    69721 ttttgaaaaa ttctaagaag accgtccttt ttatcactca cgatcgttat ttcttagacg
    69781 ctttgtcaac acggattttc gagttggagc gagcaggctt gacagaatat cagggcaatt
    69841 accaggacta tgttcgcctt aaggcagaac aggacgagcg cgatgcaact ctacttcata
    69901 aaaaagaaca actctacaaa caagaactgg cctggatgcg cagacaaccg caggcacgtg
    69961 cgaccaagca acaagctcgt atcaatcgtt tccatgatct gaaaaaggaa gtttcaggca
    70021 gtagtgctga gacagacttg actatgaact ttgaaaccag tcggattggg aagaaagtca
    70081 tcgagtttca ggatgtttcc tttgcctatg aaaataagcc cattttgcaa gattttaatc
    70141 tcttggtaca ggtcaaagat cgtatcggaa tcgttgggga caatggtgtt ggaaaatcaa
    70201 ccctacttaa cctgattgca ggaagtcttg agccgatagc aggacaagtt gtgattgggg
    70261 aaactgttcg catcgcctat ttctctcaac aaattgaggg tttggatgaa agcaagcgtg
    70321 tgatcaatta cctgcaggaa gtggcagagg aggtcaagac cagtggtggt tctacgactt
    70381 ccatcgctga gttgctggag caattcctct tcccacgttc gacgcatggg accttgattg
    70441 agaaattatc tggtggagag aaaaaacgtc tttatctcct caaactgctc ttggagaaac
    70501 caaatgttct tcttttagac gagccaacca atgacttgga tattgcaact ttgacagtct
    70561 tagagaattt cttgcaaggt tttgcaggtc ccgttttaac agtcagtcac gaccgctatt
    70621 tcttggataa ggtagcgacc aagattctcg cttttgagga tggcaagatt cgtcctttct
    70681 ttggtcatta caccgactat cttgatgaaa aagcttttga aacagatatg gccaatcaag
    70741 tgcaaaaggc cgaaaaggaa aaagtggtca aggttcgaga agacaagaaa cgcatgacct
    70801 accaagaaaa gcaggagtgg gcaagtattg aaggtgatat tgaaaccttg gaaaaacgta
    70861 tcgctgctat tgaagaggaa atgcaggcta acggctctga ctttggtaag ctggctactc
    70921 tccaaaaaga attggatgag aaaaatgaag cactccttga aaaatacgaa cgctatgagt
    70981 atctcagtga atttgatagt taagactatt cgaaaatcaa agtgcaaact atgtcggctt
    71041 cacattgccg actcaagtac agcctgtgac cggcttccta atttgcactt tgatttttat
    71101 tgagtataaa agaatagaaa aatcccgtct catgaaagga tttctctatt cttttttggt
    71161 ttcttgatga aagatatttt gccaggtttc gtggcgacgc cagatactgg tatggatgat
    71221 accatctaac tcatagcaga tgagtttggt tttttgactg atggaagtaa tttgaatgtc
    71281 cttgatagca gaatttaact cttttttggt cttataagcc tctttatcca tctgctctcc
    71341 atcttggcga atatagacaa aatcatcagt caagagttct tctagttggt ttccttggtc
    71401 aatcaattgt tcacgcataa gcaatttttt atagacattg tctaaaattt catcctcagg
    71461 gataggtgct ggttcgatat ggacatcggt atcaaagacg ccaaaacgct cctccagcat
    71521 agactcgacc tgatccgcga tttcatggct ttcaaaaaca gacaagtcag gattcatctc
    71581 tagtgtaata tccaggtaga tgttgctacc gtaggtgcga cctctttgcg atttgacctt
    71641 gctgattttg ggaatttcca tgatagcctt ttggtagtcc tcgagcaggc ggtcgtcaaa
    71701 gccatctgaa agactaaagg aagactcgat gaagatatca taggcagtct tcaagataaa
    71761 gaaagtgatg atgatagcaa ccagtttatc cacaatcgga taattgaaac tactagctag
    71821 gatggcaatg gcggttccaa gtgaggtaac agcgtcagaa agattgtcct tagcagctgc
    71881 cttcagcgcc ttggagttgg atttcttact gaggcgagta ttgtagagat agaccacaaa
    71941 cataatcgct gcagaaatga ttcctagagt tgcaccaaga ggatcaatga ccgtttcttc
    72001 ccgactgaga atcttttgaa tggtatctct tagaatatcg aaaccgacat agaacatgat
    72061 gatagaagtg atcaagcttg ccaaatcttc aatcttccaa tgaccaaaac ggtggtcacg
    72121 gtctgcaggc tggcgcgcca tccgaatccc gattaagagg gccacatttc caatgatgtc
    72181 cgatacgtta ttaaaaccat cggccaccaa actggatgaa tgaaggagat gaccagctgc
    72241 taatttagct gcagacaaga tcaaataggt cgaaatactg ataatggctc cacgctcagc
    72301 taacttgaga tttgagatag attgcttcat tcaacttcct ttctagtcac atagcattct
    72361 accattatac tggttttcaa ggaaaaattc aaataaggca gtttttactc tttgaaaact
    72421 ccccaaaatt tggtataatg gtactactca agggagtagc tggcagaaac ctgtgatagt
    72481 gtcgtcattc cgaattttat gctgaaaagt atgctttccg gccctatctt aaacagcgag
    72541 acttgttatg attaacaggt ctctttttgt ttgtcgtgaa aagatatgac agaaagagag
    72601 tctgttttgc acacaatgtc aaggaggaga cacatgtcaa aagaacaaaa acgccaagcg
    72661 ttttatactc agagccctga agaggtcttg caggctgtgg atgcgaccga gcaaggtttg
    72721 tcatcaagtg aggcggaaaa gcgccttgcc gaatttgggc acaatgaact cgaagaaggc
    72781 gagaaacgat caatcttggt caaattcatc gagcaattta aggatttgat gattatcatc
    72841 ctagttgcgg cagcaatctt gtcagtcgtg acttctggtg gggaagatat cgcagatgcc
    72901 attatcatcc tagctgtggt tatcatcaac gctgcctttg gtgtttacca agaaggaaaa
    72961 gctgaagaag ctatcgaagc cctcaaatcc atgtctagtc cagttgcccg cgttcttcgt
    73021 gatggacaca tggcagagat tgactctaaa gaattggtac caggcgatat cgttgccctt
    73081 gaagcaggtg acgtggtacc agcggaccta cgtttgctag aagccaactc tcttaaaatt
    73141 gaagaagcag ccttgacggg tgaatctgta ccagtcgaaa aagacttgtc agtcgagctt
    73201 gcgacagatg ctggtattgg tgaccgtgtc aacatggcct tccaaaactc aaacgtaacc
    73261 tatggtcgtg ggatgggtgt tgttgtcaat acaggtatgt acactgaagt tggtcatatt
    73321 gctggtatgc ttcaagatgc ggatgagact gatacaccac tcaaacaaaa cttgaacaac
    73381 ctttctaagg tcttgaccta tgctatcttg gtcattgccc ttattacttt tgtagtgggt
    73441 gtcttcattc aagggaaaaa tccacttggt gagttgttga cttctgttgc ccttgccgtt
    73501 gcagccattc cagaaggact tcctgctatc gttaccatcg ttctttctct tggtactcaa
    73561 gttttggcca aacgacattc catcgttcgt aagttgccag cagttgaaac acttggttca
    73621 actgaaatca tcgcttctga taagactggt acgctgacta tgaacaagat gacagtcgaa
    73681 aaagtcttct acgatgcggt tctacatgac tcagctgatg atattgaact aggtcttgaa
    73741 atgccactac ttcgttcagt tgtcttggcc aatgatacga aaatcgatgt ggaaggtaac
    73801 ttgattggtg acccaaccga aacagccttt atccaatatg ccttggacaa gggctatgat
    73861 gtcaaaggtt tcttagagaa atatcctcgt gtagctgaat tgccatttga ctctgaccgt
    73921 aagctcatgt caacagttca cccattgcca gatggtcgtt tccttgtagc agtcaagggt
    73981 gcgccagacc aactcttaaa acgttgtctt cttcgtgata aggctgggga tattgctccg
    74041 attgatgaga aggttacaaa tctcattcat acaaacaatt ctgaaatggc tcatcaagcc
    74101 ttgcgtgtcc ttgcaggtgc ttataagatt atcgatagta ttccagaaaa tctcacttct
    74161 gaagagcttg aaaatgattt aatttttact ggtttgattg ggatgattga ccctgaacgt
    74221 cctgaagccg ctgaggctgt tcgtgtggct aaggaagcgg gaatccgtcc gattatgatt
    74281 acaggtgacc accaagacac agcggaagcc attgccaaac gtttgggaat cattgacgca
    74341 aacgatacag aaggtcacgt tttaactggt gctgaactca atgaactgtc agatgaagaa
    74401 tttgaaaaag tcgttggtca atactctgtt tatgcccgtg tgtctccaga acacaaggtt
    74461 cgtatcgtca aggcttggca aaaacaaggt aaagtcgttg ccatgacagg tgacggtgtc
    74521 aatgacgcgc cagctctgaa aacagccgat atcggtatcg gtatgggaat cactggtaca
    74581 gaggtttcta agggggcttc tgatatgatt cttgcagatg ataactttgc gactattatc
    74641 gtcgcagtgg aagaaggacg taaggtcttc tcaaacattc aaaagactat tcagtaccta
    74701 ctttctgcta atactgctga agtattaacc atcttcctat caaccttgtt tggttgggat
    74761 gtcttacagc cggttcatct tttgtggatc aacttggtaa cggatacctt cccagctatc
    74821 gctcttggtg ttgaacctgc ggaacctggt gtcatgaatc ataaaccacg tggacgcaag
    74881 gcaagcttct tctcaggtgg tgttttgagt tctatcattt atcaaggtgt actccaagca
    74941 gctcttgtta tgagtgttta tggccttgcg attgcttacc cagttcatgt gggtgacaat
    75001 catgctattc atgcagatgc cctaacgatg gcctttgcaa cccttggttt gattcagctc
    75061 ttccatgcct acaatgtcaa gtctgtctac caatccatct tgacagttgg cccattcaag
    75121 tctaagacct ttaactggtc catcttggta tcctttatcc ttctcatggc aacaatcgtt
    75181 gtagaaccgc ttgaaggaat cttccacgta accaaactag acttgtcaca atggggaatt
    75241 gttatggctg gaagcttctc aatgattatc atcgtcgaaa tcgttaagtt tattcaacgc
    75301 aaactcggtt ttgacaagaa tgcgatttaa gggaggtttc ggatgtcagc atatcaatta
    75361 ccgaccgtat ggcaggatga agctagtaat caaggagctt ttacggggct aaacagacca
    75421 acagcaggtg cccgtttcga acaaaacttg ccaaaaggag aacaagcttt tcagctttat
    75481 tcactgggaa caccaaatgg tgtgaaggtt actatcttat tggaagaatt actagaagct
    75541 ggttttaagg aagcggctta cgacttgtat aagattgcta tcatggatgg ggatcaattc
    75601 ggctcagact ttgtgaagct caatccaaat tccaagattc cagccttatt ggaccagtca
    75661 ggtactgaaa acgtaagagt ctttgagtct gctcatattc ttctttacct tgctgagaaa
    75721 tttggagcct ttttaccaag taatcctgtg gaaaaggtag aagttttgaa ttggctattc
    75781 tggcaagcag gtgcagcacc ttttctaggt gggggatttg gacatttctt caattatgct
    75841 cctgaaaaat tggaatatcc tattaaccgt tttacgatgg aagtgaaacg ccagttggat
    75901 ttattggata aggaattggc tcagaaacct tatattgcag gcaatgacta tacgattgca
    75961 gatattgcta tctggtcttg gtatggacag ttagttcaag gaaatcttta ccaaggttct
    76021 gcaaaattct tggatgcctc aagttatcaa aatctagtaa aatgggcaga aaaaattgcc
    76081 aatcgtccag ctgttaagcg tggcttggaa gtaacttata cagaaattaa atagcaaaaa
    76141 agtcatcttc ggatggcttt ttgctacagt tgagggaaag ggtttgcagt tatcggcttt
    76201 tgtgctataa ttgctataat atagtaaaaa gcaagaggag tgtgaggaag tggaaaagaa
    76261 aattgtgaag gatatcttat ttttatctca agtgtctcag ccggcaagtc aggaggacct
    76321 ttatcttgcc agagatttgc aggatacact cttagcaaat cgtgatacct gtgttggtct
    76381 agctgccaat atgattgggg tgcagaagcg cgtgattatc tttaatcttg gcttggttcc
    76441 cgtggtcatg tttaacccag tgcttctgtc ctttgaagga tcctatgagg cagaagaagg
    76501 ctgtttgtcc ttggtaggtg tgagatcaac taagcgttat gaaaccacaa ggcttgccta
    76561 tcgtgacagc aagtggcagg aacagaccat taccttgaca ggcttcccag ctcagatttg
    76621 ccagcatgag ctggatcact tggaaggacg aatcatttag gaggaaagca aatgaaacga
    76681 atagtctttg aacttatttt tatcgcaacg acctggtata tctttttacc gccccttaac
    76741 ctgaccagct gggaatttct cttcttcctc tgtgggcatt tgttagttgt ggcaatctta
    76801 tttggctttg gcaaggggat aaaccttgtc aaaacggttc atgtgcgcca cggtaaggcg
    76861 gaagctgcct taaatcttga gggtttcaaa atcaatcggt tagggaaaat tctgttagct
    76921 tcgattggag gaattcttct cttggcagct ttggtttcct tggtaacttc cagcatgttt
    76981 caggctaaaa attatgccaa tgtagtcacg gttacggaaa aagactttac tgaatttcct
    77041 aggagtgaca ccagtaaggt tcctatccta gatagaagta ctgctgaaaa aattggagac
    77101 cgctacttgg gttccctaac cgataaggtg tcgcaatacg tagcggcaga tacctatacc
    77161 caattgacaa ttgatgggaa accttatcgg gtcacaccac tagaatatgc agaccctatc
    77221 aaatggttta acaatcaagc caagggaatc ggtgagtata tcaaggtgga catggtaact
    77281 ggaaatgcgg atttggtgga cttgaagaca ccaatcaagt attcagactc ggagtatttt
    77341 aaccgtgatg tcaaacgtca cctgcgcttg aagtacccga ctaaaatctt taaaactcca
    77401 tcttttgagg tggacgatga gggcaatcct ttctatgtag caacggttta ccaaaagcaa
    77461 tttggacttg cggttcctcg tcctgcttca gtcattatct tggatgctac aaatggagaa
    77521 accaaggaat acagcttatc agatgttcca gaatgggtgg acaggatcta tccagcagag
    77581 gaaaccattg agcaaatcaa ctacaacggc aagtacaagg acggtttctt gaatgccatg
    77641 atttccaaga aaaacgtgac ccagactacc aatggctata attacttgtc tatcggtaat
    77701 gacatctatc tctacacagg tgtgacgtcg gctaatgcgg atgagagtaa tcttggtttc
    77761 atccttgaaa atatgcgaac aggagaaatt actaagtata gcttggcttc tgcgacagaa
    77821 gaatcagccc gtgaatcagc agaaggtgct gttcaggaga aatcctacaa agcaaccttc
    77881 ccaatcctca tcaacctcaa tgacaagcct ctctacatca tgggcttaaa ggacaatgct
    77941 ggcttggtca aagagtacgc cctggtagac gcagtcgagt accaaaatgt tatcgttgct
    78001 actacagtgg aagagatgct cagcaagtat gccaataaaa acgaccttga aattgacaat
    78061 gcaacgacag aaagcatcaa gggagtagta gcagacctca aatcagctgt tatcaaggga
    78121 gacactgtct acttctttaa agttgatggc aagatataca aggtaaaggc ttcagtatcc
    78181 gatgaccttc cttaccttga aaatggtaaa accttcgaag gtcaagtagg aaaagacaat
    78241 tatctcaaga cctttaaagt acaataatac tcttcgaaaa tctctagctc tatctgcaac
    78301 ctcaaaacag tgttttgagc agcctgcggc tagtttcct
//
LOCUS       DAVLCS010000004        74389 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLCS010000004 DAVLCS010000000
VERSION     DAVLCS010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 74389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74389
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.004"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            503..1789
                     /locus_tag="VXC78_000297"
     CDS             503..1789
                     /locus_tag="VXC78_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0582446.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKGRKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            1804..2115
                     /locus_tag="VXC78_000298"
     CDS             1804..2115
                     /locus_tag="VXC78_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582447.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            2361..3089
                     /locus_tag="VXC78_000299"
                     /pseudo
     CDS             2361..3089
                     /locus_tag="VXC78_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            3471..4316
                     /locus_tag="VXC78_000300"
     CDS             3471..4316
                     /locus_tag="VXC78_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582448.1"
                     /translation="MEVINVSKHYGHSIILKDINFALNKGEIVGLVGRNGVGKSTLMK
                     ILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGFENLKYLSNLYGVDYNQERFRSLI
                     QELDLTQSINKKVKTYSLGTKQRLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVL
                     KNLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSAT
                     DRDIFITKQEFGDIVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIY
                     LNRSK"
     gene            4332..5060
                     /locus_tag="VXC78_000301"
     CDS             4332..5060
                     /locus_tag="VXC78_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582449.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLGLLISFIPPILVTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTIMMNTSNDLFIKAIELLPFYSLPVFMASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            5439..5648
                     /locus_tag="VXC78_000302"
     CDS             5439..5648
                     /locus_tag="VXC78_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0582450.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            5638..6126
                     /locus_tag="VXC78_000303"
     CDS             5638..6126
                     /locus_tag="VXC78_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582451.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            6242..7702
                     /locus_tag="VXC78_000304"
     CDS             6242..7702
                     /locus_tag="VXC78_000304"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV0582452.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            7699..8523
                     /gene="nadE"
                     /locus_tag="VXC78_000305"
     CDS             7699..8523
                     /gene="nadE"
                     /locus_tag="VXC78_000305"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV0582453.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            8873..9424
                     /locus_tag="VXC78_000306"
     CDS             8873..9424
                     /locus_tag="VXC78_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0582454.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKVYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            10139..10831
                     /locus_tag="VXC78_000307"
     CDS             10139..10831
                     /locus_tag="VXC78_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0582455.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYNV
                     DGKSGQVTESTLSQKKDSQTRVVKKRTKPQVLVQEIPIETEYLDGPTLDKSQEVEEVG
                     EIGKLLLLQSIL"
     gene            10885..11274
                     /locus_tag="VXC78_000308"
     CDS             10885..11274
                     /locus_tag="VXC78_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0582456.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(11935..12963)
                     /gene="queA"
                     /locus_tag="VXC78_000309"
     CDS             complement(11935..12963)
                     /gene="queA"
                     /locus_tag="VXC78_000309"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV0582457.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDKWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            13114..13821
                     /locus_tag="VXC78_000310"
     CDS             13114..13821
                     /locus_tag="VXC78_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV0582458.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESNLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            13961..14137
                     /locus_tag="VXC78_000311"
     CDS             13961..14137
                     /locus_tag="VXC78_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV0582459.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            14267..15202
                     /locus_tag="VXC78_000312"
     CDS             14267..15202
                     /locus_tag="VXC78_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV0582460.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            15195..15983
                     /locus_tag="VXC78_000313"
     CDS             15195..15983
                     /locus_tag="VXC78_000313"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV0582461.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGAIVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            15984..16367
                     /locus_tag="VXC78_000314"
     CDS             15984..16367
                     /locus_tag="VXC78_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV0582462.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            16383..16772
                     /locus_tag="VXC78_000315"
     CDS             16383..16772
                     /locus_tag="VXC78_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV0582463.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            16856..17986
                     /locus_tag="VXC78_000316"
     CDS             16856..17986
                     /locus_tag="VXC78_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV0582464.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            17991..18728
                     /locus_tag="VXC78_000317"
     CDS             17991..18728
                     /locus_tag="VXC78_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV0582465.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            18739..19512
                     /locus_tag="VXC78_000318"
     CDS             18739..19512
                     /locus_tag="VXC78_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV0582466.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            19502..20119
                     /locus_tag="VXC78_000319"
     CDS             19502..20119
                     /locus_tag="VXC78_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV0582467.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            20329..20730
                     /locus_tag="VXC78_000320"
     CDS             20329..20730
                     /locus_tag="VXC78_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV0582468.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            20730..21008
                     /locus_tag="VXC78_000321"
     CDS             20730..21008
                     /locus_tag="VXC78_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV0582469.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            20998..21771
                     /locus_tag="VXC78_000322"
     CDS             20998..21771
                     /locus_tag="VXC78_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV0582470.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            21772..23076
                     /locus_tag="VXC78_000323"
     CDS             21772..23076
                     /locus_tag="VXC78_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV0582471.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            23650..24528
                     /gene="pstS"
                     /locus_tag="VXC78_000324"
     CDS             23650..24528
                     /gene="pstS"
                     /locus_tag="VXC78_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV0582472.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            24528..25445
                     /gene="pstC"
                     /locus_tag="VXC78_000325"
     CDS             24528..25445
                     /gene="pstC"
                     /locus_tag="VXC78_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0582473.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            25435..26319
                     /gene="pstA"
                     /locus_tag="VXC78_000326"
     CDS             25435..26319
                     /gene="pstA"
                     /locus_tag="VXC78_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0582474.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGIYLHKKLTAA"
     gene            26330..27133
                     /gene="pstB"
                     /locus_tag="VXC78_000327"
     CDS             26330..27133
                     /gene="pstB"
                     /locus_tag="VXC78_000327"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0582475.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            27146..27904
                     /gene="pstB"
                     /locus_tag="VXC78_000328"
     CDS             27146..27904
                     /gene="pstB"
                     /locus_tag="VXC78_000328"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0582476.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            27916..28569
                     /gene="phoU"
                     /locus_tag="VXC78_000329"
     CDS             27916..28569
                     /gene="phoU"
                     /locus_tag="VXC78_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0582477.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            28726..29541
                     /locus_tag="VXC78_000330"
     CDS             28726..29541
                     /locus_tag="VXC78_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0582478.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(29561..30832)
                     /locus_tag="VXC78_000331"
     CDS             complement(29561..30832)
                     /locus_tag="VXC78_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV0582479.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            30974..31705
                     /gene="budA"
                     /locus_tag="VXC78_000332"
     CDS             30974..31705
                     /gene="budA"
                     /locus_tag="VXC78_000332"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV0582480.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            31715..32467
                     /locus_tag="VXC78_000333"
     CDS             31715..32467
                     /locus_tag="VXC78_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV0582481.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            32579..33484
                     /gene="murB"
                     /locus_tag="VXC78_000334"
     CDS             32579..33484
                     /gene="murB"
                     /locus_tag="VXC78_000334"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV0582482.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            33645..34802
                     /locus_tag="VXC78_000335"
     CDS             33645..34802
                     /locus_tag="VXC78_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582483.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEKRDEENKL"
     gene            34783..35589
                     /locus_tag="VXC78_000336"
     CDS             34783..35589
                     /locus_tag="VXC78_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0582484.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSAIGVILILTMFITMWVTKERRER"
     gene            35586..36359
                     /locus_tag="VXC78_000337"
     CDS             35586..36359
                     /locus_tag="VXC78_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0582485.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGNDMNSFTGFSLSH
                     FKTMFGDGCLMLIVTQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            36356..37426
                     /locus_tag="VXC78_000338"
     CDS             36356..37426
                     /locus_tag="VXC78_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0582486.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLEQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDLGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKSEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNAAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDA
                     AYAFINFMLKPENALKNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEIYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            37687..37926
                     /locus_tag="VXC78_000339"
     CDS             37687..37926
                     /locus_tag="VXC78_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582487.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            38201..38686
                     /locus_tag="VXC78_000340"
     CDS             38201..38686
                     /locus_tag="VXC78_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV0582488.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            38708..41326
                     /gene="alaS"
                     /locus_tag="VXC78_000341"
     CDS             38708..41326
                     /gene="alaS"
                     /locus_tag="VXC78_000341"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV0582489.1"
                     /translation="MKQLSSAQVRQMWLDFWATKAHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAAILKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(41416..42870)
                     /locus_tag="VXC78_000342"
     CDS             complement(41416..42870)
                     /locus_tag="VXC78_000342"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV0582490.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            43049..43798
                     /locus_tag="VXC78_000343"
     CDS             43049..43798
                     /locus_tag="VXC78_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582491.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELLASSY
                     ELSSSDLEASLARLLSVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            43779..45413
                     /locus_tag="VXC78_000344"
     CDS             43779..45413
                     /locus_tag="VXC78_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582492.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLFMFINIAFRFPFEEMPSFFSRMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLLLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKDRISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPILTLLGLSLYLGLPIISMIYLIMAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            46098..47261
                     /locus_tag="VXC78_000345"
     CDS             46098..47261
                     /locus_tag="VXC78_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV0582493.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDREVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVTFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            47258..47935
                     /locus_tag="VXC78_000346"
     CDS             47258..47935
                     /locus_tag="VXC78_000346"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV0582494.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            47925..48779
                     /locus_tag="VXC78_000347"
     CDS             47925..48779
                     /locus_tag="VXC78_000347"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV0582495.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            48798..49865
                     /locus_tag="VXC78_000348"
     CDS             48798..49865
                     /locus_tag="VXC78_000348"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0582496.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            49875..51041
                     /gene="aroC"
                     /locus_tag="VXC78_000349"
     CDS             49875..51041
                     /gene="aroC"
                     /locus_tag="VXC78_000349"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV0582497.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            51051..52154
                     /locus_tag="VXC78_000350"
     CDS             51051..52154
                     /locus_tag="VXC78_000350"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV0582498.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            52165..52503
                     /locus_tag="VXC78_000351"
     CDS             52165..52503
                     /locus_tag="VXC78_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV0582499.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            52595..53878
                     /gene="aroA"
                     /locus_tag="VXC78_000352"
     CDS             52595..53878
                     /gene="aroA"
                     /locus_tag="VXC78_000352"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV0582500.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            53871..54347
                     /locus_tag="VXC78_000353"
     CDS             53871..54347
                     /locus_tag="VXC78_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV0582501.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKREAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            54344..55192
                     /gene="pheA"
                     /locus_tag="VXC78_000354"
     CDS             54344..55192
                     /gene="pheA"
                     /locus_tag="VXC78_000354"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0582502.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            55189..56463
                     /gene="psr"
                     /locus_tag="VXC78_000355"
     CDS             55189..56463
                     /gene="psr"
                     /locus_tag="VXC78_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV0582503.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFVYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMIFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            56742..57587
                     /locus_tag="VXC78_000356"
     CDS             56742..57587
                     /locus_tag="VXC78_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0582504.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            57577..58680
                     /locus_tag="VXC78_000357"
     CDS             57577..58680
                     /locus_tag="VXC78_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0582505.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            58682..59668
                     /locus_tag="VXC78_000358"
     CDS             58682..59668
                     /locus_tag="VXC78_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0582506.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            59684..61117
                     /locus_tag="VXC78_000359"
     CDS             59684..61117
                     /locus_tag="VXC78_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV0582507.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMI
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            61146..62180
                     /locus_tag="VXC78_000360"
     CDS             61146..62180
                     /locus_tag="VXC78_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0582508.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            62380..63117
                     /gene="mecA"
                     /locus_tag="VXC78_000361"
     CDS             62380..63117
                     /gene="mecA"
                     /locus_tag="VXC78_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV0582509.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            63268..64554
                     /locus_tag="VXC78_000362"
     CDS             63268..64554
                     /locus_tag="VXC78_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV0582510.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRSLEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            64556..65425
                     /locus_tag="VXC78_000363"
     CDS             64556..65425
                     /locus_tag="VXC78_000363"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV0582511.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            65501..65572
                     /locus_tag="VXC78_000364"
                     /pseudo
     CDS             65501..65572
                     /locus_tag="VXC78_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            65720..66658
                     /gene="msrB"
                     /locus_tag="VXC78_000365"
     CDS             65720..66658
                     /gene="msrB"
                     /locus_tag="VXC78_000365"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0582512.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            66716..68440
                     /locus_tag="VXC78_000366"
     CDS             66716..68440
                     /locus_tag="VXC78_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582513.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQVTSDRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQKLWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDAISALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            68442..70190
                     /locus_tag="VXC78_000367"
     CDS             68442..70190
                     /locus_tag="VXC78_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582514.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANSLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNLEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            70537..71796
                     /locus_tag="VXC78_000368"
     CDS             70537..71796
                     /locus_tag="VXC78_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV0582515.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     KAVKEALTEMLQSGTTTFNDMYNPIGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    71872..72007
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            72046..72546
                     /locus_tag="VXC78_000369"
     CDS             72046..72546
                     /locus_tag="VXC78_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV0582516.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            72622..72990
                     /gene="rplL"
                     /locus_tag="VXC78_000370"
     CDS             72622..72990
                     /gene="rplL"
                     /locus_tag="VXC78_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV0582517.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            73237..>74389
                     /locus_tag="VXC78_000371"
     CDS             73237..>74389
                     /locus_tag="VXC78_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0582518.1"
                     /translation="MSLRNKIEQHIKELEGGKFQKLGDAYLSRKYNFNIVSLGSQEGT
                     DKTTKGIPDSYAVENGKYVYIMYGTHKSVISKLEGDIQSVKKKILEENIAEDKVGRLI
                     CCHTSSNITIKQKEDLEKMAEPYHLELIGINEIANDLTKIDFQYLAKEYLSISESTEQ
                     VWSINDFIRIHDESKTNAPISNDYIGDVSEIINTIKSSEKRIFLISAKPGTGKTRLAI
                     EICSLLDRNKYNIICVKSNNQDIYQDVKRNLNLHKENIVFIDDVNTTQNYISTLGLLN
                     TTSNIRFILTVRDYAKKDVINNIKVYGYNNIESELIKDDNFKELLNQFSRNDFTNQEI
                     EHIKTISKSNPRIAVIAAKLSSSQDLTNFNDEIDILKDYYEEILNKNNII"
BASE COUNT        21881 a        13683 c        16654 g        22171 t
ORIGIN      
        1 atatctatta taacatggtt taataaattc tttgagcttt tttcttttta aatattgatt
       61 gtttctaaaa gttctagtaa tattgctatt tctcattttt ccaaatatgt tattcaactt
      121 attagctacg tctctattca tatttgggta taaaacaaaa aatcaattct aacagtttta
      181 tatcagaata ataaataaaa aagcgatatt ctagactgta tcaatccttt tccattatag
      241 gagcaacaga gtgggagtag tcatctaagg actaatttat gtatttttac gagtcagtat
      301 ctttggatac tggtttttac ttttctagac tttttgacta tttgttaaaa ctgggataat
      361 tttcgactgt ttaacagtta ttatgcaaag tctaaaagat tagaattgtc aaaacaatcc
      421 gtctaggctt gattttatcc tttatttact ataaaatgag aaggaaaaat gtcaaacttt
      481 tatattgcaa ataggagaaa tcatgacaaa aacattaaaa cgtcctgagg ttttatcacc
      541 tgcagggact ttagagaagc taaaggtagc tgttcagtat ggagcagatg ctgtctttat
      601 cggtggtcag gcctatggtc ttcgtagccg tgcgggaaac tttactttcg aacagatgga
      661 agaaggcgtg cagtttgcgg ccaagtatgg tgccaaggtc tatgtagcgg ctaatatggt
      721 tatgcacgaa ggaaatgaag ctggtgctgg tgagtggttc cgtaaactgc gtgatatcgg
      781 gattgcagca gttatcgtat ctgacccagc cttgattatg attgcagcga ctgaagcacc
      841 aggccttgaa atccaccttt ctacccaagc cagtgccact aactatgaaa cccttgagtt
      901 ctggaaagag ctaggcttga ctcgtgtcgt tttagcgcgt gaggtttcaa tggaagaatt
      961 agctgagatc cgcaaacgta cagatgttga aattgaagcc tttgtccatg gagctatgtg
     1021 tatttcatac tctggacgtt gtactctttc aaaccacatg agtatgcgtg atgccaaccg
     1081 tggtggatgt tctcagtcat gccgttggaa atacgacctt tacgatatgc catttgggaa
     1141 aggacgtaag agtttgcagg gtgagattcc agaagaattt tcaatgtcag ccgttgacat
     1201 gtctatgatt gaccacattc cagatatgat tgaaaatggt gtggacagtc taaaaatcga
     1261 aggacgtatg aagtctattc actacgtatc aacagtaacc aactgctaca aggcggctgt
     1321 ggatgcctat cttgaaagtc ctgaaaagtt tgaagctatc aaacaagact tagtggacga
     1381 gatgtggaag gttgcccaac gtgaattggc aacaggtttc tactacggta taccatctga
     1441 aaatgagcag ttgtttggtg ctcgccgtaa aatccctgag tacaagtttg tcgctgaagt
     1501 ggtttcttat gatgatgcga cacaaacagc aaccattcgt caacgaaacg tcattaacga
     1561 aggggaccaa gttgagtttt atggtccagg tttccgtcat tttgaaacct atattgaaga
     1621 tttgcatgat gccaaaggca ataaaatcga ccgcgctcca aatccaatgg aactattgac
     1681 tattaaagtc ccacaacccg ttcaagctgg agacatggtt cgtgcattaa aagaaggact
     1741 catcaatttt tataaggaag atggaaccag cgtcacagtt cgagcttaag aaaggaaaag
     1801 gaaatgatag aggcacaggg tttcttagtg gataagcaaa caagatgcat tcattaccat
     1861 agcaagctgg atattattgc tttacaatgc tatgattgta aaaagtatta tgcttgttat
     1921 cggtgtcatg attcattaga aaatcaccct tttgagccgt atcccttatc tttgatacag
     1981 gataagccta ttttatgtgg tgtttgtcta aaactattaa catataagca atataaagaa
     2041 agtttaagtt gccccttttg tttttctcgc tttaatccag gttgccaaaa tcataaggaa
     2101 cgctatttta aatagcaaat catctagttt tgaagtagga gaaaactcaa ttccaagaga
     2161 aaatgaagta aatcttccca caataaaacg cataatatca agattgttca atacctgata
     2221 ctatgcgttt ttaagatttt aaagactttt ttcctttatc tggtattttg actacttgtt
     2281 aaaactgggt taattttcaa ctgtttaaca gttattatgc aaagtctaaa agattagaat
     2341 tgtcaaaaca atccgtctag agtatgcgtg atgccaaccg tggtggatgt tctcagtcat
     2401 gccgttggaa gtacgacctt tacgatatgc catttgggaa agaacgtaag agtttgcagg
     2461 gtgagattcc agaagaattt tcaatgtcag ccgttgacat gtctatgatt gaccacattc
     2521 cagatatgat tgaaaatggt gtggacagtc taaaaatcga aggacgtatg gagtctattc
     2581 actatgtatt aacagtaacc atctgctaca aggcggctgt ggatgcctat cttgaaagtc
     2641 ctgaaaagtt tgaagctatc aaacaagact tggtggacga gatgtggaag gttgcccaac
     2701 gtgaactggc tacaggattt tactatggta caccatctga aaatgagcag ttgtttggtg
     2761 ctcgtcgtaa aattcctgag tacaagtttg tcgctgaagt ggtttcttat gatgatgcgg
     2821 cacaaacagc aactattcgt caacgaaatg tcattaacga aggggaccaa gttgagtttt
     2881 atggtccagg tttccgtcat tttgaaacct atattgaaga tttgcatgat gccaaaggca
     2941 ataaaatcga ccgcgctcca aatccaatgg aactattgac tattaaagtc ccacaacctg
     3001 ttcaatcagg agacatggtt cgagctctta aagaggggct tatcaatctt tataaggaag
     3061 atggaaccag cgtcacagtt cgtgcttaat gtagttgttt agttttaaaa aattatgcaa
     3121 agctccatat acaacattta aacgagatta aagaatggcg aaatcccttg atgcgcaaga
     3181 gattagctgt ccttttttat tttttaagtg ataaagtcgg agcttaggta tcaaagccta
     3241 tcaaattaaa caaagaagcg atgtcttaga tattttgaaa aaaattaata agcagaaaac
     3301 tctctattat tttgttgtag agagtttttt attaataaaa ttttacaaaa tgacatttat
     3361 atattgcatt aagttagata tatgatataa tgttgttaaa aagaggcgca actttttaaa
     3421 ctcaataaga atcaaagagc aaaccaagaa tattaatgga ggaataaaaa atggaagtta
     3481 taaatgtaag taagcattat ggtcattcaa tcattctcaa agatataaat tttgcactta
     3541 acaagggtga aattgttggt ctagtaggga gaaatggagt tggtaagagt acgttgatga
     3601 aaattcttgt tcagaataat caaccgactt cagggaatat tataagcagt gataatgttg
     3661 ggtatttaat tgaagaacca aaattatttt tatctaaaac aggttttgag aatttaaaat
     3721 atttgtcaaa tttatatggt gttgactaca atcaagaaag atttagaagt ttgattcaag
     3781 agttagattt gactcagtct attaataaaa aagtaaagac ctattctttg ggtacaaaac
     3841 aaagattagc tttgcttcta actctcgtta cggaacctga tatattgatt ttagatgaac
     3901 cgactaatgg tttagatatt gaatcatcac aaatagtttt atcggttcta aaaaatttag
     3961 ctttacatga aaatgtggga attttaatat cgagtcataa attagaagat attgaagaaa
     4021 tttgtgagag ggttcttttc ttggagaacg ggcttttgac atttcaaaaa gtaggaaaag
     4081 atagtcataa tttcttgttt gagatagctt tttcatcagc tacagataga gacattttca
     4141 ttaccaaaca agaatttggg gatattgttc aggaagaggg actgagaatt actatgtctg
     4201 ggaatattca aagtagtgag ctttttaaat tttttaacga aaactctatt aaagtagttg
     4261 attttgaaac taaaaaagag acgcttaaag atatttatct aaatcgttca aaataaagga
     4321 aggttataat catgaaatta aataaattga attttcttaa ggaaaatata agaaatttat
     4381 attcatcagg cgtaatatat ctcggtttgc ttatctcgtt tataccgccg atattggtta
     4441 cattctttat tctaaagact caagggacat cgcttggtat taagcatatt tcaaactttt
     4501 atgctatgct cggtatgtta atggctgtta tacatgctaa tcgagtcatt agtagagatt
     4561 tttcccacaa tacggtaagt ttgttttata atcaacagaa gaatcggatg atttacgtct
     4621 tgtctaattt tctatatgcc atctcagttt ccattattta tgctttgaat ggcattgtgt
     4681 tactagtcat agtaagtaaa ttgggtattc caggtgattt aggattagat tttatagtag
     4741 ctattgtagt caatacaatt ttgttagtcc tgttttattt tctattatct tacattttct
     4801 atttatacaa attgaaaagt ggcttggtat ttggtatttt agtagcttta ctactcttta
     4861 tccctaatat attaaatacg attatgatga atactagtaa tgatttgttt atcaaagcaa
     4921 ttgaacttct tcctttttat tctttacctg tatttatggc ttcaaatacg atgtctatta
     4981 gtcagtatct tgtggtaatc actacaatca ttttattgta ctttttcact ctcaagaaaa
     5041 gcaagaagta ttcattttag tttcatttag tattattttg catacctaaa atacagtaaa
     5101 aaatcggtca tcttggtatg ctcctgctct tgttgtgtac acgtttttgt cttatgctag
     5161 actcatttcc aaaagcatta tataatagtg atatgaaatc aactaaataa gaaatacaag
     5221 caatcaaaac tcgtttaaaa gaccctacta aagctaatac taaataaaaa taaaagagta
     5281 aactaggaag tttatttcaa acaacctaaa atactgattt tcggctgaag ataatactgg
     5341 agtgcaaatt aatggggtta taataaatag ctgatagctt gtgttggttt tggatttttt
     5401 aagagtagat gagtattaaa actataagga ggacgaaggt ggctaaaaat ttaaaattaa
     5461 aattagctcg ggtagagcgt gatttaacac aaggtcaact ggcagaggct gtcggggtga
     5521 cacgccagac tattggtttg atagaggcgg gaaaatacaa tcccagtctc tcgctctgcc
     5581 agtctatttg cagatgttta gggaaaaccc tagaccaact attttgggag gaagaagatg
     5641 aaaaatagat tttattatta tcaattacta gacgaaagag aagaacaact gttcaataaa
     5701 gcgggctctg aaagtttcta tatctgcatt gctttgtcgc tcctatctta tatcatttca
     5761 gtattagcac caagcctttt taattctaat atgctgctaa tcgttatcat catagggaca
     5821 ttttactttt tcaatcgtgc ccgttatctg ggagtgacct actatagtcg ttttcatttt
     5881 acgattttgg gttgtttttt cctaaccttg gctattacgg ctcttttgat gttgcagaat
     5941 tatcaattca acatagaaat ttatcagcac aatcctttga attttaaata cctgtctgct
     6001 tgggtcatta cttatgtcat ttaccttccg tgggtcttta ttggcaatct tggtcttaag
     6061 agctatggcg aatgggctca gaaaaaattt gaacaagata tggatgaatt ggagagtgga
     6121 gaatagcttg ttactctttt ctcaatccag ctaaaatgtg atataatagt actaatttat
     6181 tggaatacat gaaagttctt gaaaattttc atgggtttct agctaaggaa gtaggaaaag
     6241 tatgtatcca gatgatagtt tgacattgca cacggacttg taccagatca acatgatgca
     6301 ggtttacttt gaccaaggga ttcacaataa gaaggcggtc tttgaggtgt atttccgcca
     6361 acagcctttt aagaacggct atgcggtttt tgcaggtttg gaaagaattg tgaactatct
     6421 tgaagacttg cgtttttcag atagtgatat agcctatttg gagtcgcttg gttatcatgg
     6481 ggcgttcttg gattaccttc gcaatttcaa gttggagttg accgttcgtt ctgcccaaga
     6541 aggggatttg gtttttgcta atgaaccgat tgtgcaggtg gaaggacctc tagcccaatg
     6601 tcagttggtc gaaacggctc ttttgaacat cgtcaactac cagaccttgg tggcgacgaa
     6661 ggcagctcgt attcgttcgg ttatcgaaga tgaacccttg atggagtttg ggacacgtcg
     6721 ggctcaagaa atggatgcgg ccatctgggg aacacgcgca gcggtgattg gtggcgccaa
     6781 tggaaccagc aacgtgcgtg cgggtaagct ctttgacatt cctgttttgg gaacccatgc
     6841 ccatgccttg gtacaggttt atggaaatga ctatgaagct ttcaaggctt acgctgcgac
     6901 ccacaaaaat tgtgtctttc ttgtggatac ctatgacacc cttcgcatcg gtgtaccagc
     6961 tgccattcag gtggcgcgtg agctgggtga tcagattaac tttatgggtg tgcggattga
     7021 ctctggggat attgcctaca tttctaagaa agtccgtcag caactggacg aggctggatt
     7081 tacagaggct aagatttatg cttctaatga tttggacgaa aatactatcc tcaatctcaa
     7141 gatgcaaaag gccaagattg atgtctgggg cgtgggtacc aagctgatta cagcttatga
     7201 ccagccagct cttggtgcag tttacaagat tgttgcaatc gaagatgaaa ctggtcagat
     7261 gcgcaatacg attaagctgt ctaataatgc tgaaaaagtg tcgacgccag gtaagaagca
     7321 ggtgtggcgc attaccagtc gtgaaaaagg caagtcagaa ggcgactata tcacttatga
     7381 tggtgtggat attagcgaca tgacagaaat caagatgttc catccgacct atacatacat
     7441 caagaagacg gttcgtaatt ttgatgccgt tcctctcttg gtggatatct tcaaagaagg
     7501 aatattagtt tacaacttgc ctagtttgac tgacattcag gattatgccc gtaaggaatt
     7561 tgacaagttg tgggatgagt ataagcgtgt gctcaatccg cagcactatc cagtggattt
     7621 ggcgcgtgat gtatggcaag ataagatgga cttgattgat aagatgcgca aggaagccct
     7681 tggtgaagga gaagaagaat gagtttgcaa gaaacgatta tccaagagct gggtgtcaaa
     7741 ccagtgattg atgcccagga agaaatccgt cgttctattg atttcttaaa aagatatctg
     7801 aaaaaacatc ccttcctaaa aacctttgta ctagggattt ctgggggaca agactcaacc
     7861 ttggcagggc gtttggcgca attagctatg gaagaactgc gagctgaaac gggagacgac
     7921 agctacaaat ttatcgctgt ccgcctgcca tacggagtgc aagctgatga agcagatgct
     7981 caaaaagccc tagccttcat ccagccagat gtcagcttgg ttgtgaatat caaggaatca
     8041 gctgatgcca tgacagctgc agttgaagcg acaggtagtc ctgtttcaga cttcaacaag
     8101 gggaatatca aggcacgttg ccgtatgatt gctcagtatg cccttgctgg ttcccatagc
     8161 ggagcggtca ttggaacaga ccacgccgcg gaaaatatca caggtttctt taccaagttt
     8221 ggtgacggcg gtgcggatat tctccctctt taccgcctca ataaacgcca aggaaaacag
     8281 ctcttgcaga aacttggcgc agagccagcc ctttatgaaa aaatcccaac ggcagaccta
     8341 gaagaagata aaccaggcct agctgacgaa gtcgcacttg gagtcaccta cgcagagatt
     8401 gacgactacc tagaaggcaa aacaatcagc ccagaagctc aagcgaccat tgaaaactgg
     8461 tggcacaaag gccaacacaa acgccactta cccatcaccg tatttgatga cttttgggag
     8521 taaaaaggtc cgggggacct ttttagcttc ttgccctgaa attaaaaagc aagaaaaacc
     8581 tccactggag gttttcagcc tctcatcttg aaataagaaa gtgagagaag gtccggggga
     8641 tcttgaaccc cgagtttaga aataagaaaa tgaggcagat tcggtaactc gaagagttcg
     8701 atttcatcgt cttacccctg caacgatgac taggtttgaa aaagattgct agagcgcatt
     8761 tcaaaccagg cagcgactgc gtcaagaaat tagaagacaa actcgttttc tagctgttac
     8821 tgagttgagt ctttttacta cgagcataga aataaggaag tgaggtagca tcatgaaatc
     8881 tatcggtacg caaatattac agacagaacg tttgatttta agaagatttg tggagagtga
     8941 tgcagaagct atgtttcaaa attgggcttc atccgctgag aatttgacct atgttacctg
     9001 ggatccccat cctgatgtcg aaatcactcg aaactcgatt cgcaattggg ttgcttccta
     9061 tactaatctc aactattaca aatgggccat ttgtctaaaa gaaaacccag agcaagtgat
     9121 aggagatatc agcatcgtta agatagacga ggctgattta agctgtgaaa tcggctatgt
     9181 gctaggcaag gtttactggg gacatggtat gatgacagag gccttgaaag ctgtcttgga
     9241 cttttgtttt actcaagcag gttttcaaaa ggtcagagca cgttatgcca gtctcaaccc
     9301 agcttcaggt cgtgtcatgg aaaaggctgg aatgtcctat ctacaaacca ttgttaatgg
     9361 tgtagagaga aaaggctatc ttgcggatct tatttattat ggtataagta gggaagaatg
     9421 ttgaattcta ttttctgttt ctatcgaagt caactattta ttgtaaatat aataattagc
     9481 attccaagtt tatttgcaat tttaaaatag catattgatt agtacaagac agatgttcta
     9541 gttccttctt taatctggtt tagtgttagt taaaaaatcg ctttaagctt gtaactaaga
     9601 gggagctaat cgactagatt ctccagccga acaggtggta atgtactttt tatagtgtaa
     9661 tcctagctgt tgttaaattt aaaatagaat cctctatcga gttagggaat taaattcaac
     9721 caattttatt catgtttttt ctatcaaatt atctaatatt aaaatagtct cattctgatg
     9781 agaaaactat tctatttata ctgcatagtt gtataaggaa tgatgaaaga tgagtgaaaa
     9841 ttatcaagtt ggaatgtttg tatctaaata tattagcatg tatttagata agatgtctgc
     9901 aatcctttat atatgagatt gattacgata tagttaaagt gttagttcaa taatcaatat
     9961 atcattctaa gtctatttta tatataaagt atattgttta acgtttgata gaaaagatgc
    10021 tatactagaa gtaggatgta atggcaaaat ctaatactaa taagcgctat gcaatacgta
    10081 aactcggaaa gatttttggt tctgcggtaa tcgggctaac tttattttta ggaggaatct
    10141 gaatacaagt tttgttcatg ctgctgatgg gattcaatat gtcagagatg atactagaga
    10201 taaagaagag ggaatagagt atgatgacgc tgacaatggg gatattattg taaaagtagc
    10261 gactaaacct aaggtagtaa ccaagaaaat ttcaagtacg cgaattcgtt atgaaaaaga
    10321 tgaaacaaaa gaccgtagtg aaaatcctgt tacaattgat ggagaggatg gctatgtaac
    10381 tacgacaagg acctacgatg ttaatccaga gactggttat gttaccgaac aggttactgt
    10441 tgatagaaaa gaagccacgg atacagttat caaagttcca gctaaaagca aggttgaaga
    10501 agttcttgtt ccatttgcta ctaaatatga agcagacaat gacctttctg caggacagga
    10561 gcaagagatt actctaggaa agaatgggaa aacagttaca acgataactt ataatgtaga
    10621 tggaaagagt ggacaagtaa ctgagagtac tttaagtcaa aaaaaagact ctcaaacaag
    10681 agttgttaaa aaaagaacca agccccaagt tcttgtccaa gaaattccaa tcgaaacaga
    10741 atatctcgat ggcccaactc ttgataaaag tcaagaagta gaagaagtag gagaaattgg
    10801 taaattactc ttactacaat ctatactgta gatgaacgtg atggaacaat tgaagaaact
    10861 acttctcgtc aaattactaa agagatggta aaaagacgta taaggagagg gacgagagaa
    10921 cctgaaaaag ttgttgttcc tgagcaatca tctattcctt cgtatcctgt atctgttaca
    10981 tctaaccaag gaacagatgt agcagtagaa ccagctaaag cagttgctcc aacaacagac
    11041 tggaaacaag aaaatggtat gtggtatttt tataatactg atggttccat ggcaacaggt
    11101 tgggtacaag ttaatggttc atggtactac ctcaacagca acggttctat gaaagtcaat
    11161 caatggttcc aagttggtgg taaatggtat tatgtaaatg catcgggtga gttagcggtc
    11221 aatacaagta tagatggcta tagagtcaat gataatggtg aatgggtgcg ttaacagatt
    11281 cctccctgcg acaaaattga taatagtatg tctgaatata taattatata taaaaagcca
    11341 tagataaggt catcttatag cgactataaa aaagtgaaca agcctagtct tctgtacatt
    11401 agaattcaga tttgttcact ttttgtttaa tactcaatga aaatcaaaga gcaaactaga
    11461 aaactagtcg caggttgctc aaagtactgc tttgaggttg tagatagaac tgacgaagtc
    11521 agtcacatat ataatccaag gtgacgttga cgcggtttga agagattttt gaagagtata
    11581 agtctttgat tttgagacta aggagagtca gggtcaaagt agtgaatgat tctgaaataa
    11641 ctcataatag tctcttgaga ggacagataa gagtaacaaa tatggtgcta ctcatgtgtc
    11701 ttgcattttg atttacaaac agcgaagaaa atataggaag ctgaaataaa atatagatga
    11761 atcaatttgg agagtcaacg caatctatgg caatattttc gaagctaggg ggaagcattt
    11821 taatttcaat gtactaggcg tcttctacag ctagctagag tttcaattgt agatgttctt
    11881 tgaaataata tcttagcgat ttattggtat tagaagaatt agagaaattc tttctcaata
    11941 aataaacatg gcgtcaccaa aactgaagaa gcggtagtgt tcttggatgg catggtggta
    12001 ggcatctaag actaattcac ggcctgcaaa ggcagaaacc aacatgacca gagttgattt
    12061 tggcagatgg aagttggttg agaaggcatc cacgaccttc cactcatacc caggtttgat
    12121 aaagatattg gtccaaccag aatctgcttg gatttgccca tcaaacttgg aaccaatagt
    12181 ttccaaggtg cggatagaag tggttccgac agcgatgacg cgaccaccat tttctttgac
    12241 agagcgaagg gtggcagcag cttcctcaga aagttgatag aactctgagt gcatttcgtg
    12301 ttcgtccaga ttatccacag aaacaggtct aaaggttccg agtccgacat ggagagtcag
    12361 atagactaga tgaacaccct tagcttggat ttctgccagc agttctttgg tgaagtgaag
    12421 accagcagtc ggtgctgcag cagagccgct ttccttggcg tagacggttt gataacgttc
    12481 acggtcatct aatttttcgt ggatataagg tggcagaggc atttctccca gactttccaa
    12541 gacttctagg aaaattcctt ggtattcaaa gcggacaatg cgtcccccgt gggtcaattc
    12601 ctctgtaacg acagcgctga ggcggccatc accaaagctg atacgagtac cgaccttgag
    12661 gcgtttggca ggtttagcca gaacttccca cttgtctcca ctagtgttct taaggaggag
    12721 aagttccaca tgacctcctg tctccacttt ttgaccatag aggcgggcag ggagaactcg
    12781 ggtgtcgttc atgacaaggg catcaccagg ttccagcata tcaataatag agtggaagtg
    12841 tttatcttgc atttctcctg tctcacggtt gacgatgagg agtttggagg catcacgttt
    12901 ttcaaggggc gtttgggcaa tcaattcctc tggcaagtgg aaatcaaaat cagctgtatt
    12961 catatatctg ttcattcttt ctaagttcta atcctatcca ttataacacg tttcaagttt
    13021 ggacgctctt tttttagaaa ttaaatcgtt ttcacttgac aaaaattggt ctataccata
    13081 taataaatat agatagaaat ggaggatgaa aagatgaaag ttattaaagt tgaaaaccaa
    13141 gttcaaggtg gaaaagttgc ttttgagatt ttgaaggaaa aattggctaa tggagctcaa
    13201 actctaggac ttgcgacagg aagtagccca cttgaatttt acaaggaaat tgttgagagt
    13261 aaccttgatt tttcaaatct aaccagtgtc aaccttgatg agtatgtggg ccttgatggg
    13321 gacaatccac agtcttatcg ttacttcatg caagaaaact tgttcaacca aaaaccattt
    13381 aaagaaagtt tcttgcctcg tggtgttaag gacaatgctg aagctgaagt tgaacgctac
    13441 aaccaaattt tggctgacca tccagttgac ctccaaatct tgggaatcgg tcgcaatggg
    13501 catatcggct ttaatgagcc tggtactcca tttgacagtc aaacgcatct agtagaactt
    13561 gaccagtcta ctattgaagc caatgcacgc ttctttgcca agattgaaga cgtcccaacc
    13621 caagctattt caatggggat taaaaacatt ttggatgcca agtctattat tctttttgct
    13681 tacggtgagt cgaaagcaga agccattgcc ggaacagtat ctggcccagt gactgagaac
    13741 ctacctgcaa gtagcctcca aaatcaccct gatgtaacca tcatcgcaga tgctgaagcg
    13801 cttagcttac tcgaaaaata aaaaagcaat gttctattga acgctttcaa ctcttgtata
    13861 aatggaagaa aaaatcaaaa ttaaaccgca tttttgcttg acaattattc cttttacgtg
    13921 tagaatgaaa tagatattga acttgaaggg agtgaaaaaa atgtctaaaa cagtagtacg
    13981 taagaatgaa tctcttgacg acgcacttcg ccgtttcaaa cgtgcggtta ctaaagctgg
    14041 tactcttcaa gaaacacgca aacgtgaatt ctatgaaaaa ccttctgtaa aacgtaaacg
    14101 taaatcagaa gtagctcgta aacgtaaaaa attctaattg gaatgaaagg ctagagaaat
    14161 ctagtccttt ttcttttaaa taaatactcc aaagcctgca aaaatctgaa acttcctcct
    14221 acaatttgat ataatagaga gaagaactca tttgaaggag gaaatgatgt cggttttagt
    14281 aaaagaagtg attgaaaagc ttagactaga tattgtctat ggtgaaccag agttgcttga
    14341 aaaggaaatc aatacagcgg atattacgcg acctggtctt gaaatgacag gctattttga
    14401 ctactataca ccagagcgga ttcaactttt ggggatgaag gagtggtctt atctgatcag
    14461 catgccttcc aacagccgtt atgaagtttt gaaaaaaatg tttctacctg agacaccagc
    14521 agtcattgtt gcccgtggtt tggtggttcc agaggagatg ttaaaggctg ctagagaatg
    14581 taagattgct attttaacca gccgtgcagc taccagtcgt ttatctggag agttatctag
    14641 ctatctggat tctcgtttgg cagaacgtac cagtgtgcac ggtgtcttga tggatattta
    14701 tgggatgggc gtcttgattc agggagatag tggaattggt aagagcgaga caggtcttga
    14761 gcttgtcaaa cgtggtcacc gtttggtagc cgatgaccgt gtcgatatct ttgccaagga
    14821 tgagattact ctctggggtg aaccagctga aattttgaaa cacttgattg aaattcgtgg
    14881 ggttggtatt atcgatgtta tgagtctcta cggtgcgagt gctgtcaagg attcttcaca
    14941 ggttcagctt gctgtctatt tggaaaatta cgatacgcat aagacctttg atcgtcttgg
    15001 aaacaatgca gaggaacttg aagtttctgg cgtagccatt cctcgtattc gtattccagt
    15061 taaaacaggt cgtaatatct ctgttgtgat tgaggcagct gccatgaatt atcgtgccaa
    15121 ggaaatgggc tttgatgcga cccgtttgtt cgacgaacga ctgacaagtc tcatcgctcg
    15181 aaatgaggtg caaaatgctt gatccaattg ctattcaact aggaccccta gccattcgtt
    15241 ggtatgcctt atgtattgtg acaggcttga ttcttgcggt ttatttgacc atgaaagaag
    15301 cacctagaaa gaagatcata ccagacgata ttttagattt tatcttagta gcctttccct
    15361 tggctatttt aggagctcgt ctctactatg ttattttccg atttgattac tatagtcaga
    15421 atttaggaga gatttttgcc atttggaatg gtggtttggc catttacggt ggtttgataa
    15481 ctggggctct tgtgctctat atctttgctg accgtaaact catcaatact tgggattttc
    15541 tagatattgc ggcgcctagc gttatgattg ctcaaagttt ggggcgttgg ggtaatttct
    15601 ttaaccaaga agcttatggt gcaatagtgg ataatctgga ttatctacct ggctttatcc
    15661 gtgaccagat gtatattgag gggagctacc gtcaaccgac tttcctttat gagtctctat
    15721 ggaatctgct tggctttgcc ttgattctga tttttagacg gaaatggaag agtctcagac
    15781 gaggtcatat cacggccttt tacttgattt ggtatggttt cggtcgtatg gtcatcgaag
    15841 gtatgcgaac agatagtctc atgttcttcg gccttcgagt gtcccaatgg ctgtcagttg
    15901 tccttatcgg tctcggtata atgatcgtta tttatcaaaa tcgaaagaag gccccttact
    15961 atattacaga ggaggaaaac taaatgttag aagttgcata tattcttgtt gccctagctt
    16021 taattgtctt tttggtctat ctgatcatta ctgtacaaaa gcttggtcgt gtcatcgatg
    16081 aaacagaaaa gacgattaaa accttgactt cagatgtgga tgtgaccttg catcacacca
    16141 atgagttgtt ggctaaggtc aatgtcttgg cagatgatat caatgtcaag gtggctacga
    16201 ttgatccact cttcagtgct gttgcagatt tatctctatc tgtttcagac ctcaatgacc
    16261 atgcgcgtgt cttgagcaag aaagcttcat cagctggttc aaaaacactc aagactggtg
    16321 caagtctgtc agctcttcgt cttgcaagta aatttttcaa aaaataaaaa aggagaatcc
    16381 ttatgggtaa attatcctca atccttttag gaacggtttc aggtgcagct cttgccttgt
    16441 ttttaacaag tgataagggc aaacaagttt gcagtcaggc tcaagatttt ctagatgatt
    16501 tgagagaaga tccggagtat gccaaggagc aagtctgtga aaaactgaca gaagttaagg
    16561 agcaggctac agattttgtt ctgaaaacaa aagaacaggt tgagtcaggt gaaatcactg
    16621 tggacagtat acttgctcaa gctaaatcct atgcttttca agcgacagaa gcatcaaaaa
    16681 atcaattaaa taatctcaag gaacaatggc aagaaaaagc cgaagctctt gatgactcag
    16741 aagagattgt gattgatata acagaagaat aaaccatcac catctccgga cggactatgt
    16801 atctggggat ggtgattttt atctggaatc tagtctttgt ggtataataa ttactatgca
    16861 gaaaaaacca acgtcagcct atgtgcacat cccattttgt acccagattt gttattattg
    16921 tgatttttca aaggtcttca tcaaaaatca gccagtcgac agctatttag agcatctgct
    16981 ggaagagttt cgttcttatg atattgaaaa gttgtcaacc ctttatatcg gtggtggaac
    17041 accgacagcc ctgtcggctc cgcaactgga ggtgttactg aatggcttga ctaaaaactt
    17101 ggacttgtct gtcttggaag agttgaccat tgaagccaat ccaggcgatt tggatgcgga
    17161 taagatagct gttttgaaaa attcggctgt caatcgtgtt tcgctaggtg tccagacctt
    17221 tgatgataag atgttgaaaa agattgggcg cagtcatttg gagaaggata tttatgaaaa
    17281 tatcgatcgt ctgaaactgg ctggttttga caacatctcc attgatttga tttatgctct
    17341 gcctggtcag accatggagc aagtaaagga aaatgtggct aaagccattg gactggatat
    17401 tccccacatg agtttgtata gtttgatttt agaaaaccat acggtcttta tgaaccggat
    17461 gcgacgtggg aaattgcctc tgcctaagga ggaactagaa gcggagatgt ttgagtacat
    17521 cattgcagag ctggagcgag cgggttttga gcattatgag atttctaatt tctccaaacc
    17581 cggttttgaa agtcgtcaca atctcatgta ctgggacaat gctgaatact atggtattgg
    17641 tgcaggggca tctggttatg tcaatggagt acgctataaa aatcatggtc ccattcgtca
    17701 ttatctcagt gcggttgagg aaggcaatgc ttgtattaca gaagatcacc tgagtcaaaa
    17761 ggagcaaatg gaagaagaaa tgttcttggg actccgcaag aaatccgggg tttccatggc
    17821 gcgatttgag gaaaaatttg gacagtcttt tgctggactt tatggagaaa ttgtcagaga
    17881 tttggttcaa caaggcctca tgcagattga gggtgaccac gttcgcatga caaagagagg
    17941 tctctttttg ggagatactg tagcagaacg atttattttg gagtaggatc atgggcttaa
    18001 cttatcaaat gaaaatgaaa attccttttg atatggctga tatgaacggt catatcaaac
    18061 ttccagatgt gattttgctg tcactgcaag tttcagggat gcagtcgatt gaactgggag
    18121 ttagtgataa ggccattttg gaagaatata atctggtctg gattatcgta gaatatgata
    18181 ttgaggtggt tcgtttgcct cgttttgcgg aagaaattac catcgaaacg gaagccttga
    18241 gctacaatcg acttttttgc taccgtcgct ttactattta taatgaagcg gagcaggagc
    18301 tcatccacat gatggcgacc tttgttctca tggaccgcga cagtcgaaaa gtccatgttg
    18361 ttgaacctga gattgtggct ccttaccagt ctgattttga taaaaaactt atccgtggac
    18421 cgaagtatga gtccttggaa gaaccgatca gcaaggatta ccatgttcgt ttttacgact
    18481 tggatatgaa tggtcatgtc aataacagta aatacttgga ctggattttt gaggtcatgg
    18541 gagcggattt tttgacccac tatattccca agaaaatcaa cctcaagtat gtcaaggaag
    18601 ttcgaccagg tggggtgatt acatcggctg ttgaacggac tggactggaa agcaagcatg
    18661 aaattacaag tgatggggtt atcaatgccc aagcaatcat tacttggcaa gaaataaaaa
    18721 aggcttaggg agaaatagat gaaatataaa ggctatttaa ttgatttaga cggaaccatt
    18781 tataagggga aagaccgaat ccctgctgga gagacttttg ttcatgaatt gcaaaagcgg
    18841 gacattccct atctctttgt aaccaacaat acaacccgca ctccagagag tgttaaggag
    18901 atgttggctc agaattttaa tatcgatacg cccctatcga ctgtctacac agcgactttg
    18961 gcaaccatcg actatatgaa tgatttgggg cttgaaaaga ccgtctatgt cgtcggagaa
    19021 gcaggactca aggaagccat caaggcggct ggttatgtgg aagacaagga aaaacctgcc
    19081 tacgtggtag ttggtctgga ttggcaagtc gactatgaaa aatttgccac agcaactctt
    19141 gctattcaaa agggtgccca ttttatcgga accaatcctg acctcaacat cccgacggaa
    19201 cgcggtcttt tgccaggtgc tggctcactg attacgctgc ttgaagtagc gacacgagtg
    19261 aagccggttt atatcggaaa accaaatgcc atcattatgg acaaggcggt tgagcactta
    19321 ggtttggaac gtgaagagtt aatcatggtt ggggacaatt atttgactga tatccgggct
    19381 gggattgaca atggcattcc aacgctcttg gtgacgacag gttttaccaa ggcagaagaa
    19441 gtagctggcc tgccaatcgc accgacacat gtggtttcta gccttgcgga gtgggatttt
    19501 gatgaaaact aaattgacct tttggggctc tatgctcttt ctcctctccc tctcaatcct
    19561 tctgaccatt tatctggctt ggattttcta tcctatggag attcagtggc taaacttaac
    19621 gaatcgagtc tatctaaaac cagaaaccat tcaatacaat tttcatatct tgatgaatta
    19681 tctgaccaat ccttttagtc aggtcttaca gatgcctgat tttcgttcgt cagcagctgg
    19741 tctgcaccat ttcgcagtgg tcaagaatct ctttcatttg gttcagctag tagctctagt
    19801 gacactgcca agtttctatg tctttgtcaa taggattgtg aaaaaggact ttttgtctct
    19861 ttatcgaaaa agtctcctgg ctctagtagt cttacctgtg atgattggac ttgggggagt
    19921 tttgattggt tttgaccaat tctttactct tttccatcaa attctctttg tgggagatga
    19981 tacctggctt tttgatccag ccaaggatcc tgttattatg attttgccag agaccttctt
    20041 tcttcatgcc ttcctcctct tttttgccct ctatgaaagc ttctttggct atctgtgtct
    20101 gaaaagtcgt aggaagtgaa atgaaagatg tttttaattt gcatatataa aaatatatat
    20161 cgtttaaaac catcgttaag agtgaattaa ccaaatccaa ttgtgtcaat cgttcgcaaa
    20221 cagcctattt ttcttgaaaa aataggcttt ttttctaaaa atccctagtc aagcgcctta
    20281 tttttttgta taatagaagt agcaaagtat agataagaag agaaaagcat gattacacta
    20341 tttctatcac cgagctgtac atcatgtcgt aaggctaagg cctggttaga aaaacataag
    20401 gttccctttg tggaacacaa tattatgacc agtcctttaa caagaaaaga attgcaacac
    20461 atcctttcct tgaccgaaaa tggtactgat gacatcattt caactcgttc aaaaattttt
    20521 caaaaattga atattgatgt agagagtatt tcggtatcgg aattgcttca tttgattgag
    20581 cagtatccta gtcttttgcg tcgtccaatt attattgatg ccaagcgtat gcaaatcggt
    20641 tttaatgaag atgagattcg tgcttttctc cctcgtagtt atcgtaagca agaactaaaa
    20701 gaagcaagaa tgagagctgg tattagttaa tgaacaaaca gtatagttac ccactagatt
    20761 tgtcgtggag cactgaagaa cttgcttcag tgctttcttt ttttaatgat gttgaagctg
    20821 cctatgaagg caaagtagag gctaaaaagt tactggactc ctataaggga ttcaaagcgg
    20881 tcgtgccaag caagagcgaa gagaaacgtt tgggacgaga atttgaaacg gttagtggct
    20941 attcacttta ccgagcagtt caggctgcca aagaaaaagg ggaaggaaag atttctcttg
    21001 gaaagtaaat ttgaatttgc taaagagctt gttaagaaag caggtcagta cattcttgac
    21061 catatgcagg aagacttgcg tgttgaaacc aagtcctctc caacagattt ggtgaccaga
    21121 ctggacaaag aagttcagga actcttggtt ggtgagattt tgtcccgtta tcctgaggat
    21181 aagatttgtg ctgaagaagg ttgtctgcga gcctcggttc aagagggcaa ggtttgggtc
    21241 attgatccca ttgatggtac caataatttt gtagcccagc aggaagattt tgctgttatg
    21301 atggcttatt ttgaaaatgg tcagggacag tttggtctga tttatgatgt ggtcaaaggg
    21361 gattgttacc acggtggtgg ggaatttcca gtttgtctaa atgataggcc cctagctcct
    21421 tttaaaacta aaccacttgg agattttctc attgcaggga atagtggtat gctggaaacc
    21481 aatgaatggg ggctggctga tttgagccga gcggttcttg gtgttcgtgt ctatggaagt
    21541 gcggccatta gttttgccaa gattttgtca gggcgtttgt tgacctatct cacttatctg
    21601 caaccatggg attatgccgc agctagtatt ttaggggaaa gtctgggcta tcgggttgtg
    21661 accctttttg gtgaagctcc tgattttcaa accagacagc cggtcatgat ggtgcctctt
    21721 gagatgcagg aggaaattca gtcctatatt tacgaaagga aaagaactta aatgcaattt
    21781 ccagaaggat ttgttgaaaa atataaagag atactaggag atgaggcaag agattttctt
    21841 gcctcttttg aggaggaagc ggtttcggcc tttcgggtca atcccttaaa agaagagcaa
    21901 ctttcctttt ctgatgccat tactcaaacc ccttggggcc actatgggaa ggtttcaggg
    21961 aaatcgcctg agcatgctac aggtttagtt tattcgcaag aacctgctgc tcaaatggtg
    22021 gctcaagtag ctcaacccag tcctggtatg aaggtcttgg acttggctgc tgcaccgggg
    22081 ggcaaatcaa ctcaactggc agcctatcta gcaggggagg ggctacttgt ttccaatgaa
    22141 atttcaagca aacgggctaa gattttggtt gaaaacatgg agcgttttgg agcgacaaat
    22201 gtcgtggtga ccaatgaatc tgccgaccgc ttggtcaagg tctttaaagg ctattttgac
    22261 ttaatcgttc ttgatgcccc ttgctctggt gaaggaatgt ttcgtaagca acctgatgct
    22321 atggactatt ggagcttaga ttatccgagt caatgtgcta gcttgcaaag agaaattctg
    22381 gaggatgcag tgaccatgtt agctgaaggt ggtcgtctgg tttattcgac ctgtacctgg
    22441 gcacccgagg aaaacgaaga gattgtcaat tggttgctgg aagagtatga ttttgacttg
    22501 ttgccagtag agcatatcaa tggaatggta gctggtattg acctgccaga aacggctcgg
    22561 atgtaccctc atcagtttaa gggagagggt cagtttgttg cccatctaca gtttaagggt
    22621 aacaatccag ctcctaaatt taaggcaagt aagagtaacc tcagccgtga acaagttgcc
    22681 ttgtggcagg aatttgccca aaaccatttg aaggtcaatc taccgggtat cttgcagact
    22741 tttggagacc agctttatct cttgccagaa cttttgccag atttagggaa gctcaagatt
    22801 gctcgcaatg gactgcatct gggcactttt aagaagaaac gctttgagcc cagtttcgct
    22861 cttggtttag ccttgaaacc gagtcaggtc gaacagtcgg ttgaaattgg ccaagaagcg
    22921 tttgtcaagt atgcggctgg agaaatcgtt cagctggcag aaagtctgcc aaatggttgg
    22981 taccaagttt tggttaaagg caatggcttg ggctttgcaa aggttactgg aaatgttttg
    23041 aaaaattatt ttccaaaagg cctcagattc aaatgaaaat gctagtcaaa tatcttattc
    23101 tatgttatag tgaaagtatg gattttttta gtaggatgat tcttgatatc ttgattgcca
    23161 ttacatgtag ttttactact caatgaaaat caaagagcaa actaggaagc tagccataga
    23221 tagctcaaaa cactggtttg aagagatttt caaagagtac aagaagttta gttattagcg
    23281 ttcttaccgc ttgtaaacta gatttctcat aaaatagaat cttttccttt tagttgtaaa
    23341 ctagtctggg agagtagaga ggtttgagat acctttctag cttttggatt atcatctaag
    23401 gagagtaatt tcccttgcat taaaaagggg aaaaagagac acgaaatgac tataatgggt
    23461 gacaatgggg gaagggatag acaagagatt ttatccacat atgaaaaaag gaggttagga
    23521 aagagtaata tagcctatat tatataaata atcaattgcg cagaaatttg gtaagaattc
    23581 atgcgtcaac tcataaagaa ctacttaaaa aattcacagt attcataatt attttcgagg
    23641 agaaaaacag tgaaaaaaag aaaaaagctt gctctgtctc ttatcgcttt ttggctgacg
    23701 gcttgtttag taggctgtgc tagctggatt gatcgtggag aatccataac ggctgttggc
    23761 tcaactgcct tgcaaccctt ggttgaagta gcggcagatg aatttggcac gatccatgtt
    23821 ggaaaaacgg tcaatgtcca agggggaggt tctggtacag gcttgtccca ggttcagtct
    23881 ggggcagttg atataggaaa ctcagatgta tttgctgagg aaaaagacgg aattgatgct
    23941 tctgctcttg ttgaccacaa ggtcgcggta gctggcttgg ctctgattgt caataaggag
    24001 gttgatgttg ataacctaac gacagagcaa cttcgtcaaa tcttcatagg tgaggtaacc
    24061 aattggaaag aggttggtgg taaggactta cccatctctg ttatcaatcg ggcagccggc
    24121 tctggttctc gtgctacctt tgatactgtc attatggaag gtcagtctgc catgcaaagt
    24181 caggagcagg attcaaatgg agcggtaaaa tcaatcgtat caaaaagtcc aggagctatc
    24241 tcttatttat ctcttaccta tatagatgat tcggtcaaaa gcatgaagtt gaatggctat
    24301 gacttaagtc cagaaaatat aagtagcaat aattggccct tgtggtctta tgagcatatg
    24361 tatacattgg ggcagcccaa tgagttggct gcagaatttc tcaattttgt tctctcggat
    24421 gagacccaag aagggattgt caaaggattg aagtatattc cgattaagga aatgaaggtt
    24481 gaaaaagatg ctgccggaac tgtgacagtg ttggaaggga gacaataatg aatcaagaag
    24541 aattagctaa gaaaatgttg cttccatcaa agaattctcg tctggagaaa ttaggaaaag
    24601 gtttgacctt tgcctgtctt tctttgatag tcatccttgt ggccatgatt ttggttttcg
    24661 tagcgcaaaa aggcttgtcg accttctttg tcaatggtgt gaatatcttt gactttcttt
    24721 tgggaggaac ttggaatcct tctagtaaag aatttggtgc ccttcctatg attttgggtt
    24781 cctttatcgt taccattctc tcagccctta tcgcaacacc ctttgctatt ggtgcagcag
    24841 tttttatgac cgaagtatca ccaaaagggg cgaagatttt gcaaccagct attgaactcc
    24901 tggttgggat tccttcagta gtgtacggat ttattggctt gcaagtcgtc gttccctttg
    24961 ttcgcagtgt ctttggtggg actggttttg ggattttgtc agggatttcc gtcctctttg
    25021 tcatgatttt gccgaccgta acctttatga caacggatag cttgcgtgcg gttcctcgtt
    25081 attatcgtga ggccagtttc gctatgggag ccactcgctg gcagactatc tggcgtgtga
    25141 tcttgaaggc ggcccgttct ggtattttca ctgcagtggt ctttgggatg gcgcgtgcct
    25201 ttggtgaggc tttagctatc cagatggttg tcggaaactc agctgttatc ccaacttcct
    25261 tgaccacacc agctgcaact ttaacttcta tattaactat gggaattggg aacactgtca
    25321 tgggaactgt aaataataat gttctctggt cactggcctt ggtactgctc ttgatgagtt
    25381 tagtttttaa cagtgtgatt aaattgatta cgaaagaaag aggaaagaaa aattatgcgc
    25441 gctaagaaat tagataaact tgcaacagct gtcctctata cgattgctag catcattgtg
    25501 acaatcttgg cttccttaat tctctatatc ttggttcggg gcttgcccca tatctcttgg
    25561 tctttcttga ctggaaggtc ttctgctttt caagcaggtg gtgggattgg cattcagctt
    25621 tacaattcct ttttcctatt ggtcattacc ttgattattt ctgtacctct ttctatggga
    25681 gctgggattt acttggctga atatgctaaa aaaggtcctg ttaccaactt tgtgcggact
    25741 tgtattgaaa tcttgtcctc tttaccatca gtggtggtgg gtctctttgg ttacttgatc
    25801 tttgtagtcc agtttgagta tgggttttca atcatttcag gtgccttggc cttgacagtc
    25861 tttaacttgc ctcagatgac gcgtaatgta gaggatagtt tgaaacacgt tcaccatacc
    25921 caacgtgagg ctggtctggc tcttgggatt tctcgctggg agacagtggt tcatgttgtt
    25981 attccagaag cgcttccagg tattgtaacg ggtgtcgtct tggcatctgg tcgtatcttt
    26041 ggcgaagctg cagctctgat ctatacagca gggcaatcgg cgccagctct tgactggtct
    26101 aactggaata tcctcagtgt gactagcccc atctctatct tccgtcaagc agaaaccttg
    26161 gctgtccata tctggaaagt caatagtgaa ggcactattc cagatggaac cattgtatca
    26221 gcaggttctg ccgctgtgct cctgatcttt atcctgattt ttaactttgg agctcgtaag
    26281 ttcggaatct atctacacaa gaaattaacc gctgcctaaa ggagaagcca tgtcaacata
    26341 taactgggat gagaagcata tccttacctt tcctgaagaa aaagtagccc tttctactaa
    26401 ggatgtccat gtttactatg gtaaaaatga atccattaag gggattgata tgcaatttga
    26461 aagaaataaa attacagctt tgattggtcc gtcgggatcg gggaaatcta cctacttacg
    26521 cagtctcaat cgcatgaatg ataccattga tattgctaaa gtaactgggc agattctcta
    26581 tcgtggaatt gatgtcaacc gtccagaaat caacgtttat gaaatgcgta aacacattgg
    26641 aatggttttt caacgcccca atccatttgc taagtcaatt taccgtaata ttacctttgc
    26701 gcatgaacgt gctggagtta aggataagca agtcctagat gaaatcgtag aaacctccct
    26761 tcgtcaggct gccctctggg atcaggttaa agacgatctc cacaagtcag ccttgacctt
    26821 atcaggtggt cagcaacaac gtctctgtat cgctcgtgcc atctctgtta agccagatat
    26881 cctcttaatg gatgagccag cctcagcctt ggatccgatt gcgaccatgc aactagaaga
    26941 gaccatgttt gagctcaaga aaaactttac catcatcatt gtaacgcata atatgcagca
    27001 ggctgctcgt gcaagtgact atacaggctt cttttacttg ggtgatttga ttgagtatga
    27061 caagactgca actattttcc aaaatgccaa gctacagtcc accaatgact atgtatctgg
    27121 tcactttggt tagaaaggaa accgtatgac agatgcgatt ttacaggtat cagacctgtc
    27181 cgtttattat aataaaaaga aggctttgaa tagtgtttcc ctatctttcc aacctaagga
    27241 aattacagcc ttgattggtc catctggatc agggaagtca accctcctca agtctctcaa
    27301 ccgcatggga gatctcaatc cagaggtgac cacaactgga tccgtggtgt acaatggtca
    27361 caacatctac agtccgcgta cagatacggt tgaattacgt aaggaaatcg gaatggtttt
    27421 ccaacaacct aatcctttcc ctatgactat ctatgagaat gttgtctacg ggcttcgtat
    27481 caatggaatt aaggataagc aggttctgga tgaagccgta gaaaaagcct tgcaaggtgc
    27541 ctctatctgg gatgaggtca aggatcgtct atatgattca gctattggat tgtcaggtgg
    27601 tcaacagcag cgtgtctgcg tggcccgtgt cttggcaact agtcctaaaa tcatcctctt
    27661 ggatgagcca acttcggctt tggatccgat ttcagctggt aaaattgagg aaaccttgta
    27721 tggtctaaaa gacaagtaca ccatgcttct ggtaacccgt tccatgcagc aagcttcacg
    27781 tatctctgat aagacaggat ttttcctaga tggagatttg attgaattta atgataccaa
    27841 gcagatgttc cttaatcccc aacacaagga aacggaagac tatattacag gaaaatttgg
    27901 ataaggagat gaaagatgtt acgatctcaa tttgaagaag atttagagaa attacataac
    27961 cagttctacg ctatgggaca agaagtgctc tcacaaatca atcgtacggt acgtgctttt
    28021 gtcacgcatg accgtgacct ggcaaaagag gtcatcgaag atgatgcaga agtaaatgaa
    28081 tacgaagtga aactggaaaa gaaatcattt gaaatgatcg cactccaaca accagtctct
    28141 caagatttgc gtacagtctt gactgtcctt aaggctgtat cagatgtgga gcgtatgggg
    28201 gatcacgctg tagccattgc tcaggcaacc atccgtatga agggggaaga gcgcattcca
    28261 gctgtagagg aagaaattaa aaaaatggga cgtgaagtta aaagcgttgt tgaagcagca
    28321 cttgatcttt atcttaatgg ttctgttgac gacgcatacc gggtggcctc catggatgag
    28381 caaattaacc actattttga aactatccgt gaccttgcga ctgaagagat taagaaaaat
    28441 ccagaagcca ttgttacggg tcgtgattat ttccaagtta tttcctactt ggagcgtatc
    28501 ggtgactatg ctaaaaatat ctgtgaatgg gttgtctact ttgaaacagg taagattgtc
    28561 gaactataaa atagtttaat tctgtataaa aaggagcttg aaatcaactg atggctcctt
    28621 tttttgaacg aaaaaatatt tttgagataa aaatttaaaa aacacttgac aagtaacttg
    28681 gatatcgtta taattataca aaattaacag agaggttgtt tatttatgaa atcaaaaaaa
    28741 tggatatttg ttttatgtaa ttttcttgca agtttcttct tagtagcttg ccagtcaggt
    28801 tctaatggtt ctcagtcagc tgttgaggcc attaagcaaa aggggaaatt agttgtggca
    28861 accagtcctg actatgcacc ctttgaattt caatcattgg ttgatggaaa gaaccaggta
    28921 gtcggtgcag acatcgacat ggctcaggct atcgctgatg aacttggggt taagttggaa
    28981 atctcaagca tgagttttga caatgttttg accagtcttc aaactggtaa ggctgaccta
    29041 gcagttgcag gaattagtgc tactgacgag agaaaagaag tctttgattt ttcaatccca
    29101 tactatgaaa acaagattag tttcttggtt cgtaaggctg atgtggaaaa atacaaggat
    29161 ttaactagcc tagaaagtgc taatattgca gcccaaaaag ggactgttcc agaatcaatg
    29221 gtcaaggaac aattgccaaa agctcaatta acttccctaa ctaatatggg tgaagcagtc
    29281 aatgaattgc aggctggaaa agtagatgct gttcatatgg atgagcctgt tgcacttagt
    29341 tatgctgcta aaaacgctgg cttagctgtc gcaactgtca gcttgaagat gaaggacggc
    29401 gacgccaatg ccgttgctct tagaaaaaat agtgatgatt tgaaagaagt ggtagacaag
    29461 gtcatccaaa aacttaagga tgaaggaatt taccaaagct atcttgaaaa agcagcaagt
    29521 ctaactgaag ttgaagaata agaaaaagca gagttggatg tcattccaat tctgctttta
    29581 aatagtttaa aacattttcc agattgtcta gggacacctt ggcaaattga taaggacagg
    29641 tacttaaata ggcctcttca aagaagtcca agcccggttg actgtgtttg agactggcga
    29701 ttttaggata ctgtctcagg tctagcaata aaccatcgtg taggggataa tgaggaaggg
    29761 gacaaggtgt tttagttatc ctttcctcga tttgtttttg gtaagattca tgattggtca
    29821 agcgagccaa acgatttttt tcaaacaatt gactgtcaat atagagtgac agggcctttt
    29881 gcataatgag gttgctgtcg tagtctagga tatttttgta ggccacaaat gcttctttga
    29941 tagcatttgg aagaatgagt gctgtaatac gaagggcagg aaaaaggctg gtcgagaagg
    30001 acttgatata aatgacatgc tcctctgtat caagatagtg gaaggtttgg cccttcttgg
    30061 agtccaaatc acccagataa tcgtcttcta cgatatagac atcatacttg gcagctaagt
    30121 taagaatgga tcgtttgtct tgctcagaat aggaatgtcc cagaggatag tgaaatcggg
    30181 gaatggtgta gaaaaactta atttttcctg ttttgaagtg gccttccagc tcctccaagt
    30241 caatcccatc aatgcctcgt tcaatcgttt gatagtccag cccctgtgca atcaagaggc
    30301 gattcatccg atggtaggtt ggctgttcca ccaagatttc cttggcttgt ctaggaaagg
    30361 atatttgaga gaggataaat aaggcttgtt gggttccaga agtcagtact agttggttag
    30421 ccttgcagta gagagcttgc tcaaagagga gtttgtgaat ggactgtctt aggtcttcta
    30481 atccttcttg attgtcatag tagttgaaga ggtagttttc tcgtccaatc aaggtttcat
    30541 tgacacagag tcggaaatcg tcataggcac tggcatgttc gtcggtaacc tcgatttcta
    30601 ggtcttgatg ttgcccttgt tctaatacat agtagccact ctgaggcttg gcatagaggt
    30661 attgttcgtg ccgtaattcc agcagggctc gttgaatggt gtccttgctg cagtgaaagt
    30721 caaggctcag ttgacggata gaaggcaggc gactacccgt cggaaatcgt ccagactcga
    30781 taccattttt cagataggaa acgacctctt tgtacttgct ttgtttcttc attccagacc
    30841 tcccttgatt ttgttacatt gtaccctttt ttttccttct tggcaatgtc tagagcgttt
    30901 ctctcgttca catctagggg caaatgtggt atacttagga gtaagattta tagaataaca
    30961 gacaagaaag tgaatggata agaacgtgca ggaaccagtg aaattatttc aatacaatac
    31021 tcttggagcc ttgatggctg gcctttatgg tggtactatg acagtaggag aattgctaga
    31081 acatggtgac cttggtttgg gaaccttgga ttccattgat ggggaattga ttgtcttgga
    31141 tggcaaggct tatcaggcca aagggtcagg agaccagcca gaaattgtgg aagtgtcacc
    31201 agatgccctt attccttacg ctgcagtggt accgcatcag gcagaggtca ttttccgcca
    31261 gcgctttgag atgacagaca aggaattgaa agaacgaatt gagtcttatt atgatgggga
    31321 aaatcttttc cgctctatca agattcgggg ggaattttca catatgcatg tgcgtatgat
    31381 tcctaagtca acacccgata ccaagtttgc tgatgtcgca acccatcaac cggaatatag
    31441 tcgtgacaat gttgcgggga ctattgttgg tttctggacg cctgagattt tccatggggt
    31501 cagtgtggca ggctaccatc tgcacttcat atcagatgat ttgaccttcg gtggacatgt
    31561 catggatttt gtcatcaagg aaggcattat cgaggtggga gcagttgacc agttggacca
    31621 acgtttccca gtccaagacc gtcaatactt gtttgctaag ttcaatgttg acgagatgaa
    31681 aaaagatatt gaaaaggcag aataggagaa gaaaatgacc attcatatca ttattaccat
    31741 gttgctgttg ctagcttttc tgataggaag catttggttt gccaaaaaga aataccagat
    31801 taatctagct gtcttgggct tgggtgcagt cgctttcttt gtctcttcgc agattttgga
    31861 aaaactggtg catatcttga ttttgcatcc tcaaaaagac ggtagtattg ccctcttgca
    31921 agatcatccg cttatctata ttatctatgg cctagccatg gcagcatttt ttgaggaaac
    31981 ggctcgtctt gttttcttca aatggttgga gaaaaagaga agtttggaaa aggcagatgc
    32041 cttggcctat ggcctagggc atggtggctt ggagttgatt tttctaggcc ttactagttt
    32101 actcaatctt tacatcgttc tttcggcagt tcaaactcag aatccacagg ttatgcaatt
    32161 actgtctgaa aatatgttaa aaaccattca gtcactttcg gtctggcaga tttatttgct
    32221 tggttttgag cgaatcttgg cgcttggttt ccaattactt ttgacagttt gggtttacca
    32281 agctgttcgc cagaagaaat ggatttatct cctagcagcc tatggcttgc atgccttctt
    32341 tgatctggca ccatctcttt tccaagtagg ctggttgaca aatccagtct tggttgaagt
    32401 gattctagca ctggagctcg ttctggtcgc ctatggaacc aaggaaatct tttgtaaaaa
    32461 atcataaaaa gggggaaacc tctttttctt atgcaaaatc caaacaaggt atttttatgg
    32521 tcgtcaaatg tctctaaaaa tggtataatg gaatgaattt tgtaaaagga agagtgacat
    32581 gtctgtaaga gaaaaaatgc ttgaaatctt agaaggaatt gatatccgtt ttcaggaacc
    32641 cttgcatagc tatagttata caaaagtagg tggagaggct gattatttgg tctttccacg
    32701 aaatcgtttt gagttggctc gccttgtgaa atttgccaac caagaaaata tcccttggat
    32761 ggttcttggc aatgccagca atatcatcgt tcgtgatggt gggattcgtg gatttgtcat
    32821 cttgtgtgac aagctcaata acgtttctgt tgatggctat accattgaag cagaagctgg
    32881 ggctaacttg attgaaacaa ctcgcattgc cctccgtcat agtttaactg gctttgagtt
    32941 tgcttgtggt attccaggaa gcgttggcgg tgctgtcttt atgaatgcgg gtgcctatgg
    33001 tggcgagatt gctcacatct tgcagtcttg taaggtcttg accaaggatg gagaaatcga
    33061 aaccctgtct gctaaagact tggcttttgg ttaccgccat tcagctattc aggagtctgg
    33121 tgcagttgtc ttgtcagtta aatttgccct agctccagga acccatcagg ttatcaagca
    33181 ggaaatggac cgcttgacgc acctacgtga actcaagcaa cctttggaat acccatcttg
    33241 tggctcggtc tttaagcgtc cagtcgggca ttttgcaggt cagttaattt cagaagctgg
    33301 cttgaaaggc tatcgtatcg gtggcgtaga agtgtcagaa aagcatgcag gatttatgat
    33361 caatgtcgca gatggaacgg ccaaagacta cgaggacttg atccaatcgg ttatcgaaaa
    33421 agtcaaggaa cactcaggta ttacgcttga aagagaagtc cggatcttgg gtgaaagcaa
    33481 gtagggagct gtatttgaaa agctgctgct atgtcatgga aaggggggtg aaagcctatc
    33541 ggtagcgaag atgtatgcag gtggttttac tccctgcaag aggtagtggc gacctgacag
    33601 agccccgatc tgttaatcta tgaaaaagaa ggaatttata ccaattgaaa aaaccaatta
    33661 tcgaattcaa aaacgtctct aaagtttttg aagacagcaa caccaaggtt ctcaaagaca
    33721 tcaactttga gttggaagaa gggaaattct acacccttct aggtgcatct ggttcgggga
    33781 aatcaactat cctaaacatt attgcaggtt tactggatgc gacgacagga gatatcatgc
    33841 tagacggtgt tcgtatcaat gatattccaa ccaacaagcg tgatgtccat acggtcttcc
    33901 aatcctatgc cttgtttccg catatgaatg tgtttgaaaa tgttgccttt ccacttcgct
    33961 tgcgcaagat tgacaagaaa gaaatcgagc aacgcgtagc ggaagttctc aagatggttc
    34021 agttggaagg ttatgaaaaa cgttccatcc gcaaactttc tggaggacaa cgtcagcgtg
    34081 tggctatcgc ccgtgctatc atcaaccaac cccgtgtggt tttgttggat gagcccttgt
    34141 cagcgctgga cttgaaatta agaacagaca tgcagtacga actgcgtgaa ctgcaacaac
    34201 gattgggcat tacctttgtc tttgtcactc acgatcagga agaagctctt gccatgagtg
    34261 actggatttt tgttatgaat gatggcgaga ttgtccagtc tggaactcct gtggatattt
    34321 atgatgaacc aatcaaccac tttgttgcca cctttatcgg ggagtcaaat atcttgccag
    34381 gtaccatgat tgaggactac ttggttgagt ttaacggcaa acgcttcgaa gcggtcgatg
    34441 gggggatgaa gccaaatgaa cctgttgagg ttgttattcg tccagaggac ttgcgcatta
    34501 cccttcctga agaaggcaag ctccaagtta aggtcgatac ccagcttttc cgtggagttc
    34561 attatgaaat tatcgcctat gacgaacttg gaaatgaatg gatgatccac tcaacccgta
    34621 aggccatcgt gggtgaggaa atcggtctgg actttgaacc agaagacatc cacatcatgc
    34681 gtctcaatga aaccgaagaa gagttcgatg ctcgtattga ggagtacgta gaaatcgaag
    34741 agcaagaagc aggtttgatc aatgcaatcg aggagaaaag agatgaagaa aacaagctct
    34801 aaactctttg tagtgcccta catgctttgg attgcgctct ttgtattggc acccttggtc
    34861 ttgattttcg gtcaatcctt tttcaacatc gaaggccagt tcagtttaga aaattacaaa
    34921 tcttactttg cgtcacaaaa cttgacctat cttaaaatga gtttcaactc agtgctttat
    34981 gcaggcattg tgacctttgt gacactgctt atcagctatc cgacggccct ctttttgacc
    35041 cgtctcaaac accgtcaact ctggattatg ctgattattc tgccaacttg gatcaacctt
    35101 cttcttaagg cttatgcctt tatcgggatt tttggtcaga atggctctat taaccaattc
    35161 ttggaattta tcggaattgg ttcacagcag ttgctattta ctgatttctc atttatcttt
    35221 gtcgcaagct acatcgagct cccctttatg attttgccga ttttcaatgt cttggacgat
    35281 atggataata atctcatcaa tgctagttac gaccttggtg caactaagtg ggagactttc
    35341 cgtcatgtca tcttccctct atctatgaac ggtgtgcgaa gtggggttca gtcggtcttt
    35401 atcccaagtt tgagtctctt catgctgacc cgtttgattg gtgggaaccg cgttatcacc
    35461 ttggggacgg ctatcgagca gaattttcta accaatgaca actatggtat gggttcagcc
    35521 attggtgtga ttctcatcct gaccatgttc atcaccatgt gggtgaccaa ggaaaggaga
    35581 gaacgatgaa aaaatttgcc aacctttatc tgggactggt ctttcttgtc ctctacctgc
    35641 cgatttttta cttgattggc tacgccttta atgcaggaaa cgacatgaac agctttacag
    35701 gctttagctt gagccatttt aaaaccatgt ttggtgatgg ttgccttatg ttaattgtga
    35761 ctcagacctt tttcttggcc ttcctatcag ccttgatagc gaccattatc gggacttttg
    35821 gtgccattta catctaccag tctcgtaaga aataccaaga agcctttcta tcactcaata
    35881 atatcctcat ggttgcgcct gacgttatga ttggtgctag cttcttgata ctctttaccc
    35941 aactcaagtt ttcacttggc tttttgaccg ttctatctag tcacgtggcc ttctccattc
    36001 ctatcgtggt cttgatggtc ttgcctcgac tcaaggaaat gaatggcgac atgattcatg
    36061 cggcctatga cttgggagct agtcaatttc agatgtttaa ggaaatcatg cttccttacc
    36121 tgactccgtc tatcattgca ggttacttca tggccttcac ctattcgctg gatgattttg
    36181 ccgtgacctt ctttgtaacg gggaatggct tttcaaccct gtcagtcgag atttactctc
    36241 gtgcacggaa agggatttcc ttagaaatca atgccctgtc tgctctagtc tttctcttta
    36301 gtattatcct agttgtaggt tattacttta tctctcgtga gaaggaggag caagcatgaa
    36361 aaaaatctat tcatttttag caggaattgc agcgattatc cttgtcttgt ggggaattgc
    36421 gactcattta gatagtaaaa tcaatagtcg agatagtcaa aaattggtta tctataactg
    36481 gggagactat atcgatccag aactcttgga gcaatttaca gaagaaacag gcatccaagt
    36541 tcagtacgag acttttgact ccaacgaagc catgtacact aagataaagc agggtggaac
    36601 gacctacgat attgccattc caagtgaata catgattaac aagatgaagg acgaagacct
    36661 cttggttccg cttgattatt caaaaattga aggaatcgaa aatatcggac cagagtttct
    36721 caaccagtcc tttgacctag gtaataaatt ctccatccct tacttctggg gaaccttagg
    36781 aattgtctac aacgaaacca tggtagatga agcgcctgag cattgggatg acctttggaa
    36841 gtcggagtat aagaattcta tcatgctctt tgatggggcg cgtgaggtgc tgggactagg
    36901 actcaattcc ctcggctaca gcctcaactc caaggatccg cagcagttgg aagagacagt
    36961 ggataaactc tacaaactga ctccaaatat caaggctatc gttgcggacg agatgaaggg
    37021 ctacatgatt cagaacaatg ctgctatcgg tgtgaccttc tctggtgaag ccagccaaat
    37081 gctagaaaaa aacgaaaatc tacgctatgt ggtaccgact gaagccagca acctttggtt
    37141 tgacaatatg gtcattccca aaacagtcaa aaaccaagac gcagcctatg cctttatcaa
    37201 ctttatgttg aaacccgaaa atgctctaaa aaatgcggag tatgttggct attcaacacc
    37261 aaacctacca gctaaggaac tgttaccaga ggaaacaaaa gaagataagg ccttctatcc
    37321 cgatgttgaa accatgaaac acctagaaat ttatgagaaa tttgaccata aatggacagg
    37381 gaaatatagc gacctcttcc tacagtttaa aatgtatcgg aagtaggaga taaacgtaag
    37441 aagacgaatc agtcaagctg gttcgttttt aaggaataga agtcagtttt tagagcccta
    37501 tctttttcta ttctagttgt ttatttgttt atttgcttat ttgcttgcct agtagtatac
    37561 taagcctata ctcttcaaac cacgtcagcg ttgccttgcc gtactcaagt acagcttgag
    37621 gctagcttcc tagtttgctt tttgattttt attgagtatt aaccttacag aaagcggcaa
    37681 caaataatga aaatgtctac ttttttcaaa aaaagtttct ggccaacctt tatgattgtt
    37741 aaccaaactg ctatactatt ccatttaaag gatggcttgg atcgacaata cctaacaact
    37801 gagtccatat attgggtgat aggcaccttt atatttggaa atattctagt agctgtgttt
    37861 agtaatatga aaatttggga taaaaagaaa aatggcagta agaaaaaata tatcctgaaa
    37921 aagtaatcag agatgtaggg aattggtcta attcaacgga gatcatttcc agttgacgca
    37981 agcttaaaaa aacgttataa taagaaagtt gagaattgat tttcacttgt cttagtccag
    38041 agaaatggcg gtgctgcgag ccatctaagc taggaagtca tgctactcaa tcatacaatt
    38101 gcataagaac aagagaatga caagttcatt gaatgaaggt ggtaccgcgg tttttcgccc
    38161 ttcgtgatat gagcttgtct tttgattttt ggaggtgttg atgaaaacat ttcttgtcaa
    38221 acaaaagttt cgtcttggag gcgaacgctt cgctatcaag gatgacaggg gagaaattgc
    38281 ctatcaggtg gagggatcat tttttaagat tcctaaaacc tttaccatct atgatgcggc
    38341 tggtgaacaa gtcagtgaga ttagtaaaga aatcttgacc ttacttcctc gttttgagat
    38401 tcagcttcgg gatggctcga gttttgtcat tcgtaagaag ttgaccttct ggcgagataa
    38461 gtatgagttt gataatctag gtcttcgtat cgagggcaat atctgggatt tgaatttcaa
    38521 attgctggat gatcgcgatc agctgattgc ggaaattaag aaggaactct tccatctgac
    38581 ctctacctat accgtaacgg ttcttgagga cgcttatgca gacctagtca tttccctctg
    38641 tgtcgcgatt gactatgtgg aaatgctgga aagccaatca cattaaacaa gtaaataagg
    38701 agacaatatg aaacaactat ctagtgcaca agtacgccaa atgtggcttg atttctgggc
    38761 gaccaaagct cactcagtag aaccatcagt aagtttggtt cctgtaaatg acccaactct
    38821 tttgtggatc aactctgggg tagcaaccct taagaaatac tttgacggga ccattatccc
    38881 tgaaaatcca cgtattacca atgcccaaaa ggctatccgt accaacgaca tcgaaaacgt
    38941 agggaagact gcgcgtcacc ataccatgtt tgaaatgctg gggaacttct ctatcgggga
    39001 ttacttccgt gacgaagcta tcacttgggc ttatgagctt ttgacaagcc ctgaatggtt
    39061 tgatttccct gctgaaaaac tttacatgac ctactatcca gacgataaag attcttacaa
    39121 ccgctggatt gaagtgggag tggatccaag tcacttgatt ccaattgagg acaacttctg
    39181 ggaaatcggt gcgggacctt ctggaccaga tacagaaatc ttctttgacc gtggggaagc
    39241 ctttgaccca gaaaatatcg gtcttcgcct gcttgcagaa gatattgaaa acgaccgtta
    39301 tattgaaatc tggaacatcg ttttgtcaca atttaacgca gaccctgctg ttcctcgtag
    39361 cgaatacaag gaattgccac ataagaacat tgatacgggc gctggtttgg agcgtttggt
    39421 ggctgttatc caaggggcta agaccaactt tgaaacggac ctcttcatgc cgattatccg
    39481 tgaagtcgag aaattgtctg gtaaggttta tgaccaagat ggcgacaaca tgagcttcaa
    39541 ggttatcgca gaccacattc gttctctttc atttgctatc ggtgatggtg cccttccagg
    39601 aaatgaaggt cgtggttatg ttcttcgtcg tcttctccgt cgtgcttcta tgcatggtca
    39661 aaaattgggt atcaacgaac ctttccttta caaattggtt ccaactgttg gaaaaatcat
    39721 ggaaagctac tacccagaag tgcttgagaa acgtgacttt attgagaaaa tcgttaagag
    39781 cgaagaagaa tcatttgccc gtacccttca ctcaggtcaa cactttgccc aaggcattgt
    39841 agcagacttg aaagaaaaag gtcaatctgt tatcgctggt tcagatgtct tcaaactcta
    39901 tgatacttat gggttcccag ttgaattgac tgaagaaatc gctgaagaag ctggtatgac
    39961 tgtagaccgt gaaggttttg aagcagccat gaaagaacag caagaacgcg cgcgtgcctc
    40021 agctgtcaag ggtggctcaa tgggtatgca aaatgaaact cttcaaaaca tcactgtaga
    40081 aagtgtcttc aactacaatg ctagccaatt gtcttctaaa ttggtagcta tcgtggcgga
    40141 caatgcagaa gtagaagctg tttcagaagg aactgcctct cttatctttg cggaaacgtc
    40201 attttatgct gaaatgggtg gacaggtagc tgactacgga caaatcttgg atgagtcagg
    40261 taaggttgtg gctactgtga ccaatgttca gaaagcccca aatggtcaag cccttcatac
    40321 agttgaagtc cttgcaccgc ttgccttgaa ccaagaatat accttggcaa ttgatagcaa
    40381 tcgccgtcac cgtgtcatga aaaaccacac tgcgactcat ttgcttcacg ctgcccttca
    40441 caatatcctt ggaaaccacg caacacaggc aggatctctt aacgaagttg aattccttcg
    40501 ctttgacttt acccacttcc aagctgtaac tgctgaagaa ttgcgtgcga ttgaacagca
    40561 agtcaacgaa aaaatctggg aagctcttga agttaagaca gttgaaacgg atattgacac
    40621 tgctaaagaa atgggagcta tggccctctt tggtgagaaa tacggcaagg aagttcgtgt
    40681 cgtgactatc ggtgactact ctattgaact ttgtggtggt actcatgttg gcaacacttc
    40741 tgagattggt ctcttcaaaa ttgtcaaaga agaaggaatc ggttcaggaa ctcgccgtat
    40801 cttggcagtg actggtaagg aagcctttga agcctatcgt gaacaagagg atgctcttaa
    40861 agctgtcgca gcaatcttga aagcacctca agtcaaggaa gtacctcaca aggtagaagg
    40921 acttcaagaa caacttcgtc aacttcaaaa agaaaatgct gagttgaaag aaaaagccgc
    40981 agctgcagcc gcaggcgata tcttcaaaga tgctaaggaa gtcaacggtc atcgttacat
    41041 tgctagtcaa gtgtctgtat ccgatgccgg tgcccttcgt acttttgcag ataactggaa
    41101 acaaaaagac tactctgatc ttcttgtcct agttgccgct atcggtgaca aagtcaatgt
    41161 ccttgtagca agcaagacaa aagaccttca tgcaggaaac cttgtcaaag aattagcacc
    41221 aatcatcgat ggacgtggtg gtggtaaacc agacatggcc atggcaggag gaagcaacca
    41281 agctaagatc caagaattgt tggatgcagt agcaggtaaa ttgtaatcaa gtaaagatct
    41341 atccatttgg gtaggtcttt ttgtgaatac aaaaaagcca aatccgcttg gacctagctt
    41401 ggttattatg agctattaga tggtattgac tgcccagaca cttacggatc tagctgagac
    41461 agggaattgt ccataacctt cctcatcaat tgtaacttga ccttggtggt taccaagtaa
    41521 atctacaaag gtttgattag tccattcttg accgacaaac attgacttgc tgttttcttg
    41581 gtcatttgag ataaggactg cgattgggga ttgattttca gcacctgaac gtacccaacc
    41641 gatacagtta gcatggtcaa agtagtcatt ttgttctcca taggccaagt cttttcggat
    41701 ggctaggagg cggtcaagga tttctttgaa atcttcttga gcatactggc ctgaaatccc
    41761 atagtagtct ccgtaaaaga cacatggaag gccgtcttgg cgtaacaaaa tgagggcata
    41821 ggctgctggc ttgaaccatt cttcaacggt agactcaagg gcttgtcctc gttgggtatc
    41881 gtggttgtcg acaaaagtca cagccttgtc aggcttgagt tcaaccaggc tatctgtgaa
    41941 aatgccacga aggtcatagt ttgcgccagc ttgactggct tcaaagagat tctggtggag
    42001 acgaacatcg acaaggtcaa agtgttcttc cgttttttcg agatagtcca gattggcttc
    42061 cttgtctggg ttccaaaatt caccaaaaac atagaaatcg tcaccgtatt tttccttcat
    42121 atcgcggatg aagttgcgca taaagaaaga gtcaatatgc ttaacggcat ccaaacggaa
    42181 accagctaca ccagtcgttt ccatgaacca atcagcccag tcatagatgt tttggatgac
    42241 ttcaggatgt ttaaagtcta ggtcggcata catgaggtag tcgtagtttc cgttttcgtt
    42301 atcgaccaat tcctcgttag cccagccctt gttgtcccct tggatcagat aaatcccaga
    42361 tttactgcgt ttggcatcgt agtctgtacc ggtgaagtgg taccaatgcc agtggaagcc
    42421 attataggta tcttggcgac catcgaaggt aaaactagtc cagccattga tggtgaaggg
    42481 ttctccaagt tcaactgtac ggtctacagg atcaacttcg ataacctgaa aggcttccct
    42541 gttatcggca gcagccttgt ggttgagaac tacatcggcc ataggttgaa ttccctgttc
    42601 tttaagggct tgaatggctt gaagatagtc ttctttgaaa ccatacttgg tgcggacagt
    42661 ccctttttgg ttgaactctc ctaagtcaaa taagtcatag accccatagc cgacatcttt
    42721 ttcgttggtt gccttgaagg ctggtggcat ccagacgtga ctgatcccca gatgagctag
    42781 gtgtggagca ttttcagcca gacgcgtcca gtgttgaccg tcgtggggca gataccattc
    42841 aaagtattgc atgagtgttt gattttgcat gatgtttcct cttacttgtc aatcttgttc
    42901 tttattctat cataaagtat ctctcggcgc aaacgtttgc gtaagataga aggaaactat
    42961 tttaactact taaaataaag tattgatttt tttgtatcaa agtgctagta tagcgatgta
    43021 taatacagat aaagatagga gttgtcccat gattgaattt caaaatgtta gtaagttgta
    43081 tggtgataaa gaggcattga gcaatctcaa tttgcagatt gaaaatgggg agattatggg
    43141 cttgattggt cataatgggg ctggaaaatc gaccaccata aaatccctag tcagtatcat
    43201 ttcacccagc agtggtcgta ttttggtaga cggtcaggag ttatcggaaa atcgcttggc
    43261 gatcaaacga aagattggct acgtagcaga ctcgcctgac ttatttttac gattaacagc
    43321 caatgaattt tgggaattac ttgcctcgtc ctatgagctg agtagctctg acttggaggc
    43381 tagtctagct aggctattga gcgtttttga ttttgctgaa aatcgctatc aggttattga
    43441 aactctttct cacggaatgc gtcagaaagt ctttgtcatc ggggcgctct tgtctgatcc
    43501 cgatatttgg gtcttggatg aacccttgac tggtttggat ccccaggctg cctttgattt
    43561 gaaacagatg atgaaggaac atgcacaaaa agggaagaca gtcttgtttt caactcatgt
    43621 cctagaggtg gcagagcaag tctgtgatcg gattgccatt ttgaaaaagg ggcatttgat
    43681 ttattgtggt agtgtagagg acttgagaaa agacaaccca gaccagtctt tggaaagtat
    43741 ctaccttagc cttgctggta gaaaagagga ggtttcagat gcgtctcaag gtcattaaaa
    43801 aattagttga tatcaatatc ctctattcat ctcaagaagc taatctggct aatctacgaa
    43861 agaagcaggc taagaatcct gggaaaaaag taaatgtttc cgctagagtc ctaagttctt
    43921 acattttttc tagtctcttg atgcttttca tgtttataaa tatagccttt cgttttcctt
    43981 ttgaggaaat gccaagtttt tttagtagga tggttgctat tttactggtg ctggcctttt
    44041 caacttcttt cactgcattt tacaatgtct tttatgagag taaggacctg gcctcctata
    44101 ggccctatgc ctttaaagaa tcagagatta taatggccaa aggtctgtct gtcctcttgc
    44161 cagctctaac tggaattgta ccaatcctag cttattttct ggtcctctac attaggctag
    44221 caccttctct gtggttgggt ttgcttttga tgctactgtc cttgacctta ttatttgtct
    44281 ctgttacttt agtgacggta gtggcagtac atttcttggc tcagactagg gtcttcagaa
    44341 agtatcagtc tattttttcg aatgtgatga ttgggatagg agttctcata cctttaatat
    44401 ttatcttctt tcttcagtcg acttttggaa gtattgttga caaagttaga gacattccat
    44461 ttctccttta tcctcttcat atcttttaca aaatagcagt ggagcctttt tcgacagaag
    44521 ccttagtggg tctgctcgct tggataggac taactctctt cctgctttat ctgaccaaaa
    44581 agaaggtcct tcctcgtttt tatgacgtga tcctgcttaa cagtgaggag aaggtcaaaa
    44641 aagaacgtcg cagcaaggat aggatttcaa ctactaaaaa gggctttttc cgtatggttt
    44701 tacgctacca cctcaccctc ttgggacagg ggactggcgt gattacagtg ctttttacaa
    44761 gtgctttcct tccttatctc atgatgatca gtctgatttc caaaatccga gattctcaga
    44821 tagttccaga cattcatcct ccatactggt tacccttgtt ttttgtagga gtgtttatag
    44881 cagttgtcaa taacaatatc accagcctgc attcaattgc cttgtccttg gagagggaaa
    44941 atgttgattt tcttaagagt ttaccctttg actttgctcg ttatgtgaaa gtgaaatttt
    45001 ggattatata tgccgtccag tcctttttac caattctgac tttacttggt ctttctctat
    45061 atctaggctt gcccatcatt tcgatgattt accttattat ggcatggatc cttgccagtg
    45121 tcatcctttc ttgccaccat tactttaagg acgttaaaaa tctgtcaacc aattggagta
    45181 gcattacgga cctggtgaat cgttcaaatg gcatagtcgc catagtttta ttgtttattt
    45241 atagtgcaat cctgatggcc cttgtaattg ggagcatatt cttggttcag tctctctcca
    45301 ctatccttgc catcagcttg ggagtaggag ctcttatcct cctgcttgct cttgctattt
    45361 ttggctatca ttattacctg tcacgcatat tggcagaaat agaaaaaaga tgagctggtt
    45421 ggtcgcttgc ttgataaatt caattcgaca aacgctttta tagtttgtta gaatgtagtt
    45481 gtaaatgatt aagattggta atcaaaaata tagggaggaa tgttttgaat aagaaatata
    45541 atatagttct attattgttg tttatagttt atttattggg atatttttca atttcaaaaa
    45601 cgttaattcc tataatgtgt gtgatccaag tatttttgat agaacatata tttagagttc
    45661 gaaatagaat gatgcaaata ggtgaaattt taattattgt tgcttctata atattattta
    45721 ttgatagtat attgagtttg taacaaaagg cttttctata aaatcaaatt ttccagatat
    45781 ctactgaagc tgatttattt cttcatcttt cttctactac ctttgtcact aaatttgaca
    45841 gacacatatt gctgatacaa cctctctacc tataatctca cggttaacct gaggctagtt
    45901 tcatagtttg ctatttgatt ttcgttgata aaaagaaatg ctcctccaag acggaagagc
    45961 attttttatt gtgattctta cacatttatt tcctagtttt gcaggaagtc tagtatacca
    46021 ttttttaaaa gaagagtaaa aaagcaaggg tagtttcttt tttgagaatt gtctaaaagt
    46081 ttgatataat ggtagttatg aatagaataa gagtcagcaa aagggttgaa aagaagcttg
    46141 ctaaggggct agttttacta gaagccagtg atcttgagaa tgtcaatctt aaggatcggg
    46201 aagtagaggt gcagggtcag gaaggaaact ttcttgggac tgcctacctt tctcagcaaa
    46261 acaagggctt gggctggttt atcagcaaag acaaggtgac cttcaatcaa gctttctttg
    46321 aaacgttgtt tagaaaagcc aaagaaaaga gaaacgccta ctatcaagat gatttgacaa
    46381 ctgcctttcg tctctttaat caagagggag atggctttgg gggtctgaca gtggaccttt
    46441 atggcgacta cgccgtcttt tcttggtata actcttatgt ttatcagatt cgtcagacta
    46501 tatcagaagc ctttagacag gttttccctg aggttttagg ggcttatgag aaaatccgct
    46561 ttaagggttt tgactatgaa tctgcccatg tttatggtca agaagcacct gactttttca
    46621 ctgttttaga aaatggtgtc ctgtatcaag tctttatgaa tgatggcttg atgacaggga
    46681 ttttcctaga ccagcatgag gttcgcggta gtttagttga cggcttggct atgggtaaat
    46741 ccttgctcaa tatgttttcc tacacagcgg ctttttcagt agctgcggcc atgggaggag
    46801 ctagccagac aacttctgtt gatctagcca aacgttcacg agaattgtct caagcgcatt
    46861 ttcaggcaaa tgggctcagc acagacgagc atcgttttat agtcatggat gtctttgagt
    46921 atttcaaata tgccaaacgc aaagacttga cctacgatgt gattgtccta gatccgccta
    46981 gctttgctcg gaataaaaaa caaactttct ctgtggccaa ggattatcac aagttgattt
    47041 cccagagtct tgagatttta aatccgggag ggattatcat tgccagtacc aatgctgcca
    47101 atgtttcccg tcagaaattt acagaacaaa ttgataaagg ttttgcagga agaagttacc
    47161 agattttaaa caaatatggt cttccagcag attttgccta taataaaaaa gatgaaagta
    47221 gtaattacct caaggtgatt agtatgaagg ttagtaaatg aaattaatcg tttcagtaat
    47281 gccaagaagt ttagaggagg ctcaggctct ggatgccacg aggtacctgg atgccgacat
    47341 cattgaatgg cgtgccgact atctgcctaa agaagcgatt ttgcaggtag ctccagccat
    47401 ttttgaaaaa ttcgcaggcc gtgagttggt tttcacgcta cgaactcgct ccgaaggtgg
    47461 agaaatcgac ctttctccag aagagtatat ccatctaatc aaggaagttg cgcaactcta
    47521 tcaaccagac tatattgatt ttgagtacta tagctacaag gatgtttttg aggaaatgct
    47581 ggacttccca aatcttgttt tgagttacca taatttccaa gaaacacctg agaacatgat
    47641 ggaaatcttg tcagagttga cgatcctaaa tccaaaactt gttaaggttg cggtgatggc
    47701 tcacacggag caggatgtct tagacttgat gaactataca cgaggcttta aaaccctcaa
    47761 tcctgaacag gaatatgtga ccatttctat gggtaaggtg ggcaaggtct ctcgtatcac
    47821 tgcggatgtg actggttcga gttggtcttt tgccagtctg gatgaggtta gtgcccctgg
    47881 gcagatttct ctagctagca tgaaaaaaat cagggagatt ttggatgaag cttgatggct
    47941 atacacgttt agctgcagtt gttgccaatc ctattaagca ttctatttct cccttcatcc
    48001 acaatagagc ctttgaggcg acagctacca acggtgctta tgtggcttgg gagattgaag
    48061 cgagtgactt ggcagaaaca gtggccaata ttcgtcgcta ccagatgttt ggcatcaatc
    48121 tgtccatgcc ctataaggag caggtgattc cttatttgga tgagctaagc gatgaagcgc
    48181 gcttgattgg tgcggttaat acggttgtca atgagaatgg caatttaatt ggatataata
    48241 cagatggcaa gggatttttt aagtgcttgc cttcttttac aatttcaggt aaaaagatga
    48301 ccctgctggg tgcaggtggt gcggctaaat caatcttggc acaggctatt ttggatggcg
    48361 tcagtcagat ttcggtcttt gttcgttccg tttctatgga aaaaacaaga ccttacctag
    48421 acaagttaca ggagcagaca ggctttaaag tggatttgtg tgctttagaa tatgtttctg
    48481 aactgcaagc aaggattgcc gagtcggatt tgctagttaa tgccaccagt gtgggcatgg
    48541 atggccaatc ctctcctgtt cctgaaaaca tagtcttacc agaaactctc ttagttgcag
    48601 atatcatata ccaacccttt gaaacaccgt ttttgaaatg ggctagaagt cagggcaatc
    48661 cagcagtcaa tggtctggga atgttgctct atcaagctgc agaagctttt caactgtgga
    48721 caggcaagga aatgccgaca gaagagattt ggcagtcttt aacagaaaaa taccaataaa
    48781 gaaagggaga ctctcctatg aaaatcagaa tcgatattcc tcatcatcct tatgatattc
    48841 agattgaaaa aggttgtatg gcccaggctg gtcagtggtt gcgagaactc tggcaaccgc
    48901 aaaaggtagt cattgtgaca gataaccatg tagcctctct ctatgcagag aaggtcaagc
    48961 tcagcctaga agatgctggt tttcaggtag ctgtttttga tttcttagaa ggtgaagaaa
    49021 gaaagaattt aactactgtt cagaaagtct atgaatttct agtcaagcaa ggtctgactc
    49081 gtagcgatgg aatcgttgct cttggtggtg gcgttgttgg ggacctggct ggctttgtag
    49141 cctctaccta tatgcggggt attcactttg ttcagattcc gactagtttg acagctcagg
    49201 ttgattcttc tatcggtgga aagacaggcg ttaacacacc atttgctaaa aatatggtgg
    49261 ggacctttgc ccaaccagat ggggttctga ttgatccact tgttcttgaa accctcggaa
    49321 aaagagagtt gattgaaggg atgggtgaag ttatcaagta tggcttgatt gaggatccag
    49381 aactgtgggc tctcttgacg ggactgaatg gttctgttga gagtattttg gaacatgcag
    49441 agaccttgat tgaacattct tgtcaggtga agcgcaagat ggtggttgaa gatgagttgg
    49501 acaatggtat tcgtctttac ctcaattttg gccacactat tggccatgcc atcgaagcga
    49561 ctgccggtta tggcaaggtc atgcatggag aggctgttgc catgggaatg gtacagattt
    49621 ccaaggttgc tgaggaaaaa ggcctcatgc cagctggcat tacccaatct atcacagaga
    49681 tgtgtcagaa attcggcttg cctgttgact atgaaaattg ggaagttgac aagctttatc
    49741 aggctcttac tcatgacaag aaagcgcgtg gtaacacctt gaaattggtc ttggtgccag
    49801 agcttggttc agcgatcatt cacccagttt ctctggaaga gatgaaagac tacttggtaa
    49861 aataaggaga gtgtatgaga tatttaactg caggagaatc acacggcccc cgtctaacag
    49921 ctattattga gggaattcca gctggacttc cattgacagc tgaggatatc aatgaggacc
    49981 ttagacgccg tcagggtggc tacggtcgtg gtggtcgtat gaagattgag agtgaccagg
    50041 ttgtctttac ttcgggcgtt cgccacggga agacgacagg ggcgcctatt actatggatg
    50101 tcatcaataa ggaccaccag aaatggctgg acatcatgtc tgcggaggac attgaagacc
    50161 gccttaaaag caagcggaaa attactcatc ctcgcccagg tcatgccgat ttggttgggg
    50221 ggattaagta ccgttttgat gatttgcgaa attctttgga gcgttcatca gctcgtgaaa
    50281 ccaccatgcg ggtggcagtt ggtgcagtag ccaaacgcct cttggctgag ctggatatgg
    50341 agattgccaa ccatgtcgtg gtctttggtg gcaaggaaat cgatgttcct gaaaatctga
    50401 cagtcgctga aattaagcaa agagctgccc agtctgaagt ttctattgtc aaccaagaac
    50461 gagaacagga aatcaaggac tatattgacc aaatcaaacg tgatggtgat accatcggtg
    50521 gggttgtgga gacagtcgtc ggaggcgttc cagttggtct tggttcctat gtccaatggg
    50581 atagaaaatt ggatgcaaga ttggctcaag ctgttgtctc tatcaatgcc tttaaagggg
    50641 tggaatttgg tcttggcttt gaggctggtt atcgtaaagg cagccaagtt atggatgaaa
    50701 ttctctggtc taaagaagac ggttatactc gccgtaccaa taatctaggt ggttttgaag
    50761 gtggtatgac taatgggcaa cccatcgttg ttcgtggggt catgaaaccc attcctactc
    50821 tttataaacc tcttatgagt gtggatatcg aaacccacga accttacaag gcaaccgtgg
    50881 agagaagtga tccgactgct cttccagctg caggaatggt catggaagca gttgtagcaa
    50941 cggttctggc gcaagaaatc ctcgaaaaat tctcatcaga taatcttgag gaactaaaag
    51001 aagcggtagc caaacaccga gactatacaa agaactatta aggagttcct atggcaaaaa
    51061 caatctatat cgcaggtctt gggttgattg gagcctctat ggcacttggt atcaaacgcg
    51121 atcatccaga ttatgaaatt ttaggttata atcgtagtca agcttcgaga gatatcgcct
    51181 tgaaagaagg catgattgac cgtgcaacgg atgattttgc tagttttgct cctttggcag
    51241 atgtcattat cctcagcttg ccaatcaaac aaactattgc tttcattaag gagttggcca
    51301 atttggattt gcgagaaggc gttattattt cagatgctgg ttcgaccaag tcaaccattg
    51361 tggatgcggc ggagcagtat ttggctggca agtctgttcg ctttgtcggg gcccatccca
    51421 tggctggtag tcacaagaca ggggctgctt cggcagatgt caatcttttt gaaaatgcct
    51481 attatatctt tacaccttca agcctgacaa gtcaggacac gcttaaggaa atgaaggatc
    51541 tgctttcagg tcttcatgct cgttttatcg agattgatgc caaggagcat gatcgtgtca
    51601 cttctcagat tagccatttt cctcatattt tggcttctag tctcatggag cagactgcgg
    51661 tctatgctca agagcatgag atggcaaggc gctttgcggc aggtggtttt cgagatatga
    51721 cccgaattgc ggaaagcgag ccaggaatgt ggacctccat tctcttgtcc aatagcgaga
    51781 ccattctgga tagaattgag gatttcaagg aacgtttgga agtgattggt caggccatta
    51841 gtaagggaga tgaagagcaa atttggaact tttttaacca agcgcgtgaa caacgccaga
    51901 ccatggaaat ccataagcgt ggtggtgtgg atagctctta cgacctctat gttgacgttc
    51961 ctgatgaaga agatgtcatc ctgcggattt tggaactgct acgtggaact tccttggtta
    52021 acatccacat caacgaggaa aatcgtgagg atattcacgg aatcctacaa atttcattta
    52081 aaaatgctca agacttggaa agagctgagc atctcataac agaaaatacc gactatacag
    52141 tcgtcatcaa ataaggagaa gaacatgtca aatatttacg atagtgcaaa cgaactcagt
    52201 cgcggtctac gcggattacc agaatacaag gctgttaaag cagctaaaga tgcgattgca
    52261 gcagatgctg aggcaagcaa aatctttaca gaatatcttg cctttcaaga ggaaattcaa
    52321 aaactagcac agacaggtca aatgccagat gcgtccttcc aagctaagat ggaaggcttt
    52381 ggtaaacaga ttcaaggaaa tagcctcttg tcagaattct ttaccaagca acaacaattg
    52441 gccatttacc tttctgacat tgaaaaaatt gtttttgaac cagtttcaga attgctgaaa
    52501 taagaaaaga acgatcctaa agtcaggaat ttttaaggaa tttctggctt tttatgataa
    52561 aataggtaaa agtattgcaa gtatgaggtc cagtatgaaa ctaaaaacaa acattcgcca
    52621 tttacatggt agtatccgcg tcccaggtga caagtctatc agccaccgtt ccattatctt
    52681 tggaagtttg gctgagggtg agaccaaggt ttatgatatt ctgcgaggtg aagacgttct
    52741 ttcgaccatg caggtttttc gtgaccttgg tgttgaaatt gaggataaag atggggttat
    52801 taccattcaa ggtgtaggca tggctggctt aaaagcgcca caaaatgccc ttaatatggg
    52861 aaattctggc acctcgattc gcctgatttc aggtgtcctt gctggtgcag atttcgaagt
    52921 agagatgttt ggagatgata gtctttccaa acgtcctatg gaccgtgtga cccttccact
    52981 gaaaaaaatg ggcgtcagca tttcagggca aactgaacga gacttgcctc cccttcgctt
    53041 aaaagggacg aaaaacctaa gacctattca ttatgagttg ccaattgcct ctgcccaagt
    53101 caagtcagcc ttgatgtttg cagccttaca agctaagggg gagtcagtta ttatcgaaaa
    53161 agagtacacc cgtaatcata ctgaagatat gttgcaacaa tttggtggtc atttaagtgt
    53221 ggatggtaag aaaatcacag tccaagggcc acaaaaattg acaggacaga aggtggtcgt
    53281 accaggagat atttccagtg cagccttttg gttagtcgca ggtttgattg ctccaaattc
    53341 tcgtctagtg ctgcagaatg tggggatcaa cgaaactcgc accggtatta ttgatgtcat
    53401 tcgtgccatg ggtgggaaat tggaaataac tgaaatcgat ccagtcgcta aatctgcaac
    53461 cttgattgtt gagtcttctg acttgaaagg aacagagatt tgtggcgctt tgattccacg
    53521 tttgattgat gaattgccta ttattgccct acttgcgacc caagcccaag gtgtaacagt
    53581 tatcaaggat gctgaggagc tcaaggtcaa ggaaacagac cgtattcagg ttgtggcaga
    53641 cgccttaaat agtatgggag cagatattac tcctacggca gatgggatga ttatcaaagg
    53701 aaaatcagct cttcacggtg ctagagtcaa tacgtttggt gaccaccgta tcggcatgat
    53761 gacagctatc gcagccctat tggttgcaga tggagaggtg gagcttgacc gtgcagaagc
    53821 catcaatacc agctatccta gtttctttga tgatttggag agcttgattc atggctaagg
    53881 tgttattagg gtttatgggg gctggaaaat cgactattgc aagaggcttg gaccctaatt
    53941 accttgatat ggatgctctg attgagaagc gcctaggtat gtccattgcg aattttttcg
    54001 ctgaaaagag agaagcagcc tttcgtcagg tagaatcaga agtcctagct gatttactac
    54061 aaacagacca agtcgtgtca actggaggag gagtggttat ttctcagaga aatcgtgact
    54121 tactcaagac taatacagat aacatctacc tgaaagctga ttttgaaacc ctctaccaac
    54181 gtatcgtagc tgataaggac aatcagcgac cgctttttct aaataatagc aaggaagaac
    54241 tagtagctat ttttcaagaa agacaggctt ggtatgagga agtggctagt cgggttttgg
    54301 atgtgaccaa gctaagccca gaggaaatta tagaggaact aagatgaaaa ttgcttatct
    54361 aggtcccaag ggatcatttt cacaccacgt tgtgcagaca gcttttcctc atgaggaatt
    54421 gcaggctttt gccaacatta cagatgtcat caaggcttat gagcaaggat tagtggacta
    54481 ttctgtggtg ccagttgaaa attctattga gggtagtgtt catgaaacct tggactatct
    54541 ttttcatcag gctcacatcc aagcagtagc agaaatcgtt cagcctattc atcagcagtt
    54601 gatggtggtt ccaggccata ctaagattga aaagattttt tcacatccac aggccttggc
    54661 tcaaggaaag aaattcatcg atgaacaata tccagaggct caaatcgagg taacagctag
    54721 tacagcttat gcggcccgtt ttatttccga acatccagat cagccctttg cagcaattgc
    54781 acctagaagt tctgctgaag aatatggatt ggaactgatt gccgaggata ttcaggaaat
    54841 ggaagccaat ttcacccgtt tctgggttct aggagctgaa aagcctagta ttcccttgca
    54901 agcacaaact gaaaagatga gtttggcctt gacattacct gacaaccttc caggtgcact
    54961 ttataaggcc ctgtcgacct ttgcttggcg aggaattgac ttgacaaaaa ttgaaagtcg
    55021 tccactcaag acagcactgg gtgaatactt tttcattatt gatgtggatt ataccgataa
    55081 ggacttggtc cactttgccc aaaaagaatt agaagcgatt ggaatccagt ataaaattct
    55141 gggtgcctat cctatttatc caatatcaga ccatggaaag gagagaagat gagtaaagaa
    55201 aatcccttaa gtcatcatga gcagttgcgt tatgattatt tgctaaaaaa tattcactat
    55261 ctcaatgaga gagaaaaaaa tgagtttgtc tatttgcaag aaaagctaac tcttgctagg
    55321 ggaaatagta gctctagctt ggaacaagaa agagaagagc aggttgactt accaagctat
    55381 gcgaaccgga gtcgctcaca atccaaatca caagcactct ctttccctcc aaaaaagaaa
    55441 agacggaagc tccgtcttaa acgaattttt atggtgattt tttcactttt ggtctgtgtg
    55501 gctttggcca tgatattcat gtttttgcgt ggttaccaag atgctagcgc aaagaaaact
    55561 gctgatgccc gggcagctca agtagaagtc tttaatggtc aggacactag agatggagtt
    55621 aatattttaa tcatgggtac tgatggtcga atcggccaga acagtgttga gacacgaact
    55681 gactctatta tggtattaaa tgtcgggggc tcagataaga aaatgaagct agtcagtttc
    55741 atgcgtgata atttggtcta tatagatggt tatagtcaag tgattaacgg tagaaaacag
    55801 acagataaca agttaaacgt agcctacgag ttaggagaac aagaggggca aaaaggggca
    55861 gaaatggttc gccaagtctt gaaagataat tttgacttgg acattaagta ctacgccttg
    55921 gttgatttcc aggcctttgc cacagcgatt gacacacttt tccctgatgg ggtgacgatt
    55981 gatgctcaat tttcaacatt gaatgggcgt cccctaacag aagctacagt cggagatgat
    56041 ttatatgcta ccgagactga gtctccaacc caaaccatta aagtcggaaa acagcagatg
    56101 aatggctcga ccctgctcaa ttatgctcgt ttccgtgatg atgatgaggc ggattacggc
    56161 cgtacaaaaa gacagcaaca agttttaaca gcaattttag agcaaattaa agatcccact
    56221 aaacttttca ctggttctga agctcttgga aaggtttttg ctatgacctc aaccaacgta
    56281 ccctatactt tcctcctaac aaacggttta tctgttttgg atggagcaaa aaatggtatt
    56341 gaaaaattga cgattccaga actgggtgac tgggtagatg cctatgatgt ttatggaggc
    56401 ttgggcttgc tggttgatca aaacaaatat caaaccaagc tcgctcaaat gggcttgaga
    56461 taagataata ctcaatgaaa attaaagtgc aaactaggaa gctagccgca ggctgctaaa
    56521 aacacagttt tgaggttgta gataagactg acgaagtcag ttacctatac ctacggcaag
    56581 gtgaagctga cgtggtttga agagattttc gaagagtata agacagaaaa atcaaagttt
    56641 gatagctatt tggatagcag tcaggctttg attttttaca gtctgcaata gattttcacc
    56701 ccttgtttgt ggtataatga aacgatacga tagaaagaat aatgaacaat atgactgatt
    56761 taaaagcaat tcaggctcgt agtctggaga tggctgaata ttttgtggcc ttttgtaaag
    56821 aacatgattt gctctgttat ctctgtggcg gaggcgctat tggtaccctt cgaaacaagg
    56881 gatttattcc ttgggacgac gacctagact tttttatgcc tcgtaaagat tatgagaaat
    56941 tagcagaatt atggcctcgt tatgcagatg aacgttattt cttgtcaaag agttacaagg
    57001 attttgttga tcgtaatctt tttattacca ttcgtgacaa ggaaaccacc tgtatcaagc
    57061 cttatcagca ggatttggat ttgccacatg gtctggcctt ggatgttttg cctttggatt
    57121 attatccgaa agatccagct gagcggaaaa aacaggttcg ttgggccttg atttattcac
    57181 tcttttgtgc gcaaactatt ccagaaaagc atggtgctct catgaaatgg ggaagtcgca
    57241 ttttactggg tttgactcca aaatctctcc gttatcgcat ctggaaaaaa gctgagaaag
    57301 aaatgactaa gtatgatttg gctgattgtg atggcattac agaattatgc tcaggtcctg
    57361 gctacatgag aaacaagtac ccaatcacat cttttgaaga caatcttttc ttgccatttg
    57421 aaggaacaga gatgcctatt ccaatcggct atgatgtcta tctcagaact gcttttgggg
    57481 attatatgac gcctccacca gcagacaagc aggtaccgca tcatgatgct gtcatcgctg
    57541 atatggataa gtcttataca gaatacaagg gagaatatgg tggctaagaa aaaaatctta
    57601 ttttttatgt ggtctttttc tcttggaggt ggtgcagaga agattctatc aaccattgtt
    57661 tcaaatctgg atctagaaaa gtatgatatt gatattcttg aaatggagca ctttgacaag
    57721 ggatatgaat ctgttccaaa gcatgtacgc attttaaaat cccttcaaga ttatcgccaa
    57781 accagatggt tacgagcttt tttgtggaga atgagaattt attttccaag actggctcgt
    57841 cgtttgcttg taaaagatga ttatgatgtt gaagtttctt ttaccattat gaatccacca
    57901 ctgttgttct ctaaaagaag agaagtcaag aagatatctt ggattcatgg aagtattgaa
    57961 gaacttctta aggatagctc taaaagagaa tcacatagaa gccagttgga tgctgcgaat
    58021 acaattgtag ggatttcaaa aaagaccagc aattctatca aggaagttta tccagattat
    58081 acttctaaat tacagacaat ctacaatgga tatgattttc agactattct agaaaaatct
    58141 caagagaaga tcgatatcga gattgctcct caaagtatct gtactatcgg acggattgag
    58201 gaaaataagg gttctgaccg tgtagtggaa gtgatacgat tattacacca agagggaaaa
    58261 aactatcatc tctattttat cggggctggt gatatggaag aggaactgaa aaaacgagtc
    58321 aaagagtatg ggattgagga ctatgtacat ttccttggtt atcaaaaaaa tccttatcag
    58381 tatctatctc agacgaaagt tcttttgtct atgtctaaac aagaaggttt tcctggagtg
    58441 tatgtggagg ccttgagtct gggactccct tttatctcta cggacgttgg aggggctgag
    58501 gaattatccc aagaaggacg atttggacaa atcattgaga gcaatcaaga ggcagctcag
    58561 gcgattacta attacatgac ttctgcctca aactttgatg tcgatgaggc tagccaattc
    58621 attcaacaat ttacaattac aaaacaaatc gaacaagtag aaaaactatt agaggagtag
    58681 catggaaact gcattaatta gtgtgattgt gccagtctat aatgtggcgc agtacctaga
    58741 aaaatcgata gcttccattc agaagcagac ctatcaaaat ctggaaatta ttcttgttga
    58801 tgatggtgca acagatgaaa gtggtcgctt gtgtgattca atcgctgaac aagatgacag
    58861 ggtgtcagtg cttcataaaa agaacgaagg attgtcgcaa gcacgaaatg atgggatgaa
    58921 gcaggctcac ggggattatc tgatttttat tgactcagat gattatatcc atccagaaat
    58981 gattcagagc ttatatgagc aattagttca agaagatgcg gatgtttcga gctgtggtgt
    59041 catgaatgtc tatgctaatg atgaaagccc acagtcagcc aatcaggatg actattttgt
    59101 ctgtgattct caaacatttc taaaggaata cctcataggt gaaaaaatac ctgggacgat
    59161 ttgcaataag ctaatcaaga gacagattgc aactgaccta tcctttccta aggggttgat
    59221 ttacgaagat gcctattacc attttgattt aatcaagttg gccaagaagt atgtggttaa
    59281 tactaaaccc tattattact atttccatag aggggatagt attacgacca aaccctatgc
    59341 agagaaggat ttagcctata ttgatatcta ccaaaagttt tataatgaag ttgtgaaaaa
    59401 ctatcctgac ttgaaagagg tcgctttttt cagattggcc tatgcccact tctttattct
    59461 ggataagatg ttgctagatg atcagtataa acagtttgaa gcctattctc agattcatcg
    59521 ttttttaaaa ggccatgcct ttgctatttc taggaatcca attttccgta aggggagaag
    59581 aattagtgct ttggccctat tcataaatat ttccttatat cgattcttat tactgaaaaa
    59641 tattgaaaaa tctaaaaaat tacattagaa cgggggtgac caagtgattg atgggaaacg
    59701 attattattt agtttgacca tagtcagtta tgccttgacg ctagtaagtg gaattgtgta
    59761 tctgtttaat aataataatg ttagcttact ttctacttta ttgttcttgt tggttagtag
    59821 cttaattgct tgttggaatg atatcaagta ttacttaatc cattttattt tctatttaac
    59881 catttttgta tttctggtat caagaccgac cattgattat tttagggatg gtgctttgga
    59941 tacctatcat ccaatagcct atcgttttgc ctttatagtt gtcatgattt cgattctggg
    60001 cttgaccaca ggaggcattc tggctcgtta cttcatagct aggaagaaaa taaaagtagc
    60061 aaatatagga aattctctaa aagaggttta tatcaagcgg ttacgctttg tatcactagg
    60121 agtttttctt ctaacttatc ctttctattt cattcggtta tttgaacggc tcttgtatcg
    60181 tttgcagact tcctactatg cctactatgc aaattttgaa agtaaactgc cttattttac
    60241 ctacattttg tctaccttta cggtctatgc aatgtgtatg tatctggcaa ccaagccaaa
    60301 gaaattgcag gccacagcag tgcttgtctc ctttattgca gctaatacta ttcatttggc
    60361 aattgggaca cgaaatccct ttattttaag tattttattt gcttttgttt attactttat
    60421 gcgggagcaa actgaaaaag gaaaatggat tgggtttaaa gaaaagttag cgatttttgt
    60481 aggttctcct attctcatgt tagcgatggg agtactcaat tatgtacggg ataatgtcca
    60541 agtttcccat acaggtttct gggatatctt acttgacttt atctataaac aagggactag
    60601 ttttggtgtt ctggctcgag gttttctatt taacagtagc ctcccttacc gagatttccg
    60661 taattttact tttggtcctg ttcttgatta ttttgcaagg gggagtttgg gagccatttt
    60721 cggaggaaaa gcctttgaac atacaaccaa tagtgtggaa ctagctattg atagtaatag
    60781 ttatgcccac aatctatcct atcttgtctt gaacaaggaa tacttgaaag ggcatggtat
    60841 cggaagtagt tatatcatgg agttgtatac cgactatggt atgattggag tctttctgct
    60901 tagtttctta ctcggcgtat tatttatagc catgctgcaa gtagcctatc gctcaaggac
    60961 aatcctattt gctttatccc tactcatctt gaataatcta ttctttatgc caagaagcag
    61021 cttttcagaa agtttcttca atttatttac aatgcaattc tggggaattg ttcttgtgat
    61081 tatatttgta gcaaaaatgc ttacaaagga aaactagtat ctactaaaca aaggagaaaa
    61141 aaatcatgtt tgaacattat tcagtagctg atttgtttgc aaatctttat aaaaagcgaa
    61201 aagcaaatat tttagctctc atcgctttat ttgctctcat tgctgtacca tttacaatta
    61261 aagcagttag gaataaaaac actgtcaaag atacaacaag ttattcaact tatcttatct
    61321 ataaaatcac tcctccaaaa gagtcggcca aaacgatttt gaatcatcaa attggtggtt
    61381 atagtgattt ttatgggaaa ttgattgatg gtaatttgaa tggagcttat cttttcaatg
    61441 atgtagaacc cagtgagttg aaaaaaattg ccagtgaatt agacacgaca gaaacaacct
    61501 tgaaaaattc aacgaatgac tattggtgga aaaaattgac cgtctactat atgattgacg
    61561 atgcaggggt tggtgtgaaa attttgacat caagtaaaga tgccaatgac ttgttagaga
    61621 aaaaaattga tgggttgatt gagaaattta aacatgccta tgcaaatgtg aaaattgaaa
    61681 aactggaaac catcaactct aaagaattga acgcaaatgg tgaaacagcg cttggcttaa
    61741 atgtgaaaaa tctgattctt cgtttagttg ttattggagt ggtttgtgtg attttggttg
    61801 tgatgggaaa tgtgttagtt tatctcttta atccaacaat caatagagta ggtgattttt
    61861 ctcagtatca aattgatttt gtaacagaga ttacaacaat tgctaaccta gcagatgttt
    61921 tgtcatacaa aaatactgga caggaattga ccatcgttag ctcaaataaa gctatcttag
    61981 ataaattgaa acagagtcaa gaagctttaa aaggaatgca ttttgtagat ttacaggatg
    62041 tatcatctct tttggaaaga gatacagtcc ttcttgttga agagtacgga gtgactcgtt
    62101 ataagaaatt tgagcaaagt cttcaaattc tcagaaactt aaatcgttct atcctcggtg
    62161 tagcaacctt taaattataa gtattctgat gtataaggtc ttcaaaatcg gctaagagcc
    62221 gattttgaag gctttttcta tctgcctgca gaaattttct tttggagtct cctatagaaa
    62281 gaccctaggg aaaatctatc cgtatagagg agccttcttt tgataaaatc gtaaaaatct
    62341 agtataatag atagaactga aagtatgagg ttactagcaa tgaaaatgaa acaaattagt
    62401 gatacaactt taaaaatcac gatgtcttta gaggatttga tggatcgtgg aatggagatt
    62461 gctgactttc tcgttcctca agaaaaaaca gaagagttct tttatgctat cttggatgag
    62521 ctagagatgc ctgatagctt tctggataca ggcatgttga gcttccgtgt gactccaaaa
    62581 cctgataagg tagatgtctt tgtgaccaag tcaaagattg accaaaatct agattttgaa
    62641 gacttatcgg atttgccaga tatggaagaa ttggctcaaa tgtctccaga tgaatttatc
    62701 aaaaccctgg aaaaaagcat cgcagacaaa accaaggatg atatcgaagc cattcaatct
    62761 cttgagcaag ttgaagccaa ggaagaagag caagagcaag ctgaacaaga agctgagagt
    62821 aagaaagaac cttacatcta ctacatcctt tcttttgcta agttggctga cttggtagct
    62881 tttgccaaga cagtgacttt tgaaatggaa acttctgaac tctacaaaat gaacgagcgc
    62941 tattatttga ccattttagt ggatattgaa aatcatccaa gcccatatcc agcttggctg
    63001 ttggcccgta tgcgcgagtt tgcagacgat agtgatatca gtcgctcagt cttacaagag
    63061 tatggtcaag tcttgatgag tcacgatgca gtgctcaatc tgcaaaaaat cggctaatcc
    63121 tttctggaaa gctattttca gattttaaga agagcgaatc gtctgattcg ttttttcttt
    63181 ttatactgaa atagtgattt actataatag gaattttcac aaaattctgt tataatggct
    63241 atattagaaa atttcgagga gataaagatg acagttaaaa ttgctttact aggatttggt
    63301 accgttgcaa gtggtgtgcc tttcctccta aaggaaaatg gaggaaaaat caatcaatca
    63361 gcacattcag atatcaaagt tgctaaggta ttggtcaagg atgaagatga aaaaaatcgc
    63421 ttgcttgcag cagggaatga ctttaacttt gtaaccaatg tggatgatat tttatcagac
    63481 caggatatta ctatcgtagt ggaattgatg gggcgtattg agcctgctaa aacctttatc
    63541 actcgttcct tggaagctgg aaaacacgtt gttactgcta acaaggacct tttagctgtc
    63601 catggcgcag aattgctaga aatcgctcaa gctaacaagg tagcacttta ctacgaagca
    63661 gcagttgctg gtgggattcc aattcttcgt actttagcaa attccttggc ttctgataaa
    63721 attacgcgcg tgcttggagt agtcaacgga acttccaact tcatggtgac caagatggtg
    63781 gaagaaggct ggtcttacga tgatgctctt gcggaagcac aacgtctagg atttgcagaa
    63841 agcgatccga cgaatgacgt agatgggatt gatgcagcct acaagatggt tattttgagc
    63901 caatttgcct ttggcatgaa gattgccttt gatgatgtag cccacaaggg aatccgcaat
    63961 atcacaccag aagacgtagc tgtagctcaa gagcttggtt acgtagtgaa attggttggt
    64021 tctattgagg aaacttcttc aggtattgct gcagaagtga ctccaacctt cctacctaaa
    64081 gcgcacccac ttgctagtgt gaatggcgta atgaacgctg tctttgtaga atctatcggt
    64141 attggtgagt ctatgtacta cggaccaggt gcgggtcaaa aaccaactgc aacaagtgtt
    64201 gtagctgata ttgtccgtat cgttcgtcgt ttgaatgatg gtaccattgg caaagacttc
    64261 aacgaatata gccgtgactt ggtcttggca aatcctgaag atgtcaaagc aaactactat
    64321 ttctcaatct tggctccaga ctcaaaaggt caggtcttga agttggctga aatcttcaat
    64381 gctcaagata tttcctttaa gcaaatcctt caagatggca aagagggtga caaggcgcgt
    64441 gtcgttatca tcacacacaa gattaataaa gcccagcttg aaaatgtctc agctgaattg
    64501 aagaaggttt cagaattcga cctcttgaat accttcaagg tgctaggaga ataagatgaa
    64561 gattattgta cctgcaacca gtgccaatat cgggccaggt tttgactcgg tcggtgtagc
    64621 tgtaaccaag tatcttcaaa ttgaggtctg cgaagaacga gatgagtggc tgattgaaca
    64681 ccagattggc aaatggattc cacatgatga gcgtaatctc ttgctcaaaa tcgctttgca
    64741 aattgtacca gacttgcaac caagacgctt gaaaatgacc agtgatgtcc ctttggcgcg
    64801 cggtttgggt tcttccagct cggttatcgt tgctgggatt gaactagcca accaactggg
    64861 tcaactcaac ttatcagacc atgaaaaatt gcagttagcg accaagattg aagggcatcc
    64921 tgacaatgtg gctccagcca tttatggtaa tctcgttatt gcaagttctg ttgaagggca
    64981 agtctctgct atcgtagcag actttccaga gtgtgatttt ctagcttaca ttccaaacta
    65041 tgaattacgt actcgcgaca gccgtagtgt cttgcctaaa aaattgtctt ataaggaagc
    65101 tgttgctgca agttctatcg ccaatgtagc ggttgctgcc ttgttggcag gagacatggt
    65161 gaccgctggg caagcaatcg agggagacct cttccatgag cgctatcgtc aggacttggt
    65221 aagagaattt gcgatgatta agcaagtgac caaagaaaat ggggcctatg caacctacct
    65281 ttctggtgct gggccgacag ttatggttct ggcttctcat gacaagatgc caacaattaa
    65341 ggcagaattg gaaaagcaac ctttcaaagg aaaactgcat gacttgagag ttgataccca
    65401 aggtgtccgt gtagaagcaa aataaagaat agaagatagg atggggaaac tcttgaccag
    65461 agggtttcat atcctttttg tgaaaagaag tttatactca atgaaaatca aagagcaaac
    65521 taggaagcta gccgcaggct gctcaaaaca gtgttttgag gttgtggata gaactgaaga
    65581 agtcagctca agacactgtt ttgaggttgc agatagaact gacgaagtca gtaacatata
    65641 tacggtaagg tgacgctgac gtggtttgaa gagattttcg aagagtatta gttaaaaacg
    65701 tgataaagga gaaataaaga tggcagaaat ttatctagca ggtggttgtt tttggggcct
    65761 agaggaatat ttttcacgca tttctggagt gctagaaacc agtgttggct acgctaatgg
    65821 tcaagtcgaa acgaccaatt accagttgat caaggaaaca gaccatgcag aaacggtcca
    65881 agtgatttac gatgagaagg aagtgtcact cagagagatt ttactttatt atttccgagt
    65941 tatcgatcct ctatctatca atcaacaagg gaatgaccgt ggtcgccaat atcgaactgg
    66001 gatttattat caggatgaag cagatttgcc agctatctac acagtggtac aggagcagga
    66061 acgcatgctg ggtcgaaaga ttgcagtaga agtggagcaa ttacgccact acattctggc
    66121 tgaagactac caccaagatt atctcaggaa gaatccttca ggttactgtc atatcgatgt
    66181 gaccgatgct gataagccat tgattgatgc agcaaactat gaaaagccta gtcaagaggt
    66241 gttgaaggcc agtctatctg aagagtctta tcgtgtcaca caagaagctg ctacagaggc
    66301 tccatttacc aatgcctatg accaaacctt tgaagagggg atttatgtag atattacgac
    66361 aggtgagcca ctcttttttg ccaaggataa gtttgcttca ggttgtggtt ggccaagttt
    66421 tagccgtccg atttccaaag agttgattca ttattacaag gatctgagcc atggaatgga
    66481 gcgaattgaa gttcgttctc gttcaggcag tgctcacttg ggtcatgttt tcacagatgg
    66541 accgcgggag ttaggcggcc tccgttactg tatcaattct gcttctttac gctttgtggc
    66601 caaggatgag atggaaaaag caggatatgg ctatctattg ccttacttaa acaaataaaa
    66661 cagagagtgg ggcttcccac tttcttcatt tctagaatat gaatagaagg gatttatgaa
    66721 acacctatta tcttacttca aaccctacat caaggaatca attttagccc ccttgttcaa
    66781 gctgttagaa gctgtttttg agctcttggt tcccatggtg attgctggga ttgttgacca
    66841 atctttacct cagggagatc aaggtcatct ctggatgcag attggcctgc tccttatctt
    66901 tgcagtaatt ggcgttttag tggccttgat agctcaattt tactcagcaa aggcagcagt
    66961 aggttttgct aaggaattga caaacgatct ttatcgtcat attctttcct tgcccaagga
    67021 cagcagagac cgtctgacaa cttctagttt ggtcactcgc ttgacttcgg atacctacca
    67081 gattcagact ggtatcaatc aattcctgcg tctcttttta cgagcgccca ttatcgtttt
    67141 tggtgccatt tttatggctt atcgaatctc agctgagttg actttctggt tcttagtcat
    67201 ggttgccatt ttgaccattg tcattgtagg gttatctcga ttggtcaatc ctctctacag
    67261 tagtctcaga aagaaaacgg accaactggt tcaggaaacg cgccagcaat tgcaagggat
    67321 gcgggttatt cgtgcttttg gtcaagaaaa acgagagtta cagatttttc aaacccttaa
    67381 ccaagtttat gctagattac aagaaaagac aggtttctgg tctagtttat taacacctct
    67441 gacctatctg attgtcaatg gaactcttct cgttattatc tggcaaggct atatttcaat
    67501 tcaaggagga gtgctcagtc aaggtgctct cattgctctt atcaattacc tcttacagat
    67561 tttggtggaa ttggtcaagc tagccatgtt gataaattcc ctcaaccagt cctatatctc
    67621 agccaagcga atcgaggaag tctttgttga ggctccagag gatatccatt cagaattaga
    67681 acaaaagcaa gttaccagtg atcgggtttt acaagtccaa gaattgacct ttacctatcc
    67741 tgatgcggcc cagccttctc tgagagacat ttcctttgat atgactcaag gacaaatcct
    67801 tggtatcatt ggggggactg gttctggtaa atcaagcttg gtgcaactct tacttggact
    67861 ttatccagta gacaagggga acattgacct ttatcaaaat ggacgtagtc ctcttaattt
    67921 ggagcagtgg cggtcttgga ttgcctatgt acctcaaaag gtcgaactct ttaaaggaac
    67981 cattcgttcc aacttgactc taggtttcaa tcaagaagta tctgaccaga aactctggca
    68041 ggccttggag attgcgcaag ctaaggattt tgtcagtgaa aaggaaggac tcttggatgc
    68101 cctagttgag gcaggggggc gaaatttctc aggtggacaa aaacaaaggt tgtctatcgc
    68161 ccgagcagtc ttgcgccaag ctccgtttct catcctagat gatgcaatct cggcactgga
    68221 taccattaca gagtccaagc tcttgaaagc tattagagaa aattttccaa acatgagctt
    68281 aattttgatc tctcaacgaa cctcgacttt acaaatggcg gaccagattc tcctcttgga
    68341 aaaaggtgag ttgctagctg ttggcaagca cgatgacttg atgaaatcca gtcaagtcta
    68401 tcgtgaaatc aatgcatccc aacatggaaa ggaggactag aatgaaacga caaactgtaa
    68461 accagacgct caaacgttta gtcgtagatt tagcaaacca tcccttcctc cttttcctag
    68521 cctttctagg aactattgcc caagttggct tatcaattta cctacctatt ctgattgggc
    68581 aggtcattga ccaagtccta gtggctggtt catcaccagt tttttggcag atttttctcc
    68641 agatgctctt ggtggtaata ggaaatactc tggtacaatg ggccaattct ctcctctata
    68701 atcgtctaat cttctcttat accagagatt tacgggagcg aatcatccat aagctccatc
    68761 gtttaccgat tgcctttgta gataggcaag gtagtggaga gatggttagt cgtgtaacca
    68821 cggacatcga acagttggca gctggcttga ccatgatttt taaccaattt ttcattggtg
    68881 ttttgatgat tttggttagt attctagcca tgctccaaat tcatctcctc atgactctct
    68941 tagtcttgct gttgacgcca ctgtccatgg tgatttcacg ctttattgcc aagagatcct
    69001 atcatctctt ccagaagcaa acagagacga ggggaattca gactcagttg attgaagaat
    69061 cgcttagcca gcagactata atccagtcct tcaatgctca aacagaattt atccaaagat
    69121 tgcgtgaggc tcatgacaac tactcaggct attctcagtc agccatcttt tattcttcaa
    69181 cggtcaatcc ttcgactcgc tttgtaaatg cactcattta tgccctttta gctggagtag
    69241 gagcttatcg tatcatgatg ggttcaacct tgaccgtcgg tcgtttagtg acttttttga
    69301 actatgttca gcaatacacc aagcccttta atgatatttc ttcagtgcta gctgagttgc
    69361 aaagtgctct ggcttgcgta gagcgtatct atggagtctt agatagccct gaagtggctg
    69421 aaacaggtaa ggaagtcttg accagtgacc aagttaaggg agctatttcc tttaaacatg
    69481 tctcttttgg ctaccatcct gaaaaaattt tgattaagga cttgtctatc gatattccag
    69541 ctggtagtaa ggtagccatc gttggtccga caggtgctgg aaaatcaact cttatcaatc
    69601 tccttatgcg tttttatccc attagctcgg gagatatctt gctggatggg caatccattt
    69661 atgattatac acgagcatca ttgagacagc agtttggcat ggtgcttcaa gaaacctggc
    69721 tcacacaagg gaccattcat gataatattg cctttggcaa tcttgaagcc agtcgagagc
    69781 aagtaattgc tgctgccaaa gcagctaatg cagacttttt cattcaacag ttgccacagg
    69841 gatacgatac caagttggaa aatgctggag aatctctctc tgtcggccaa gctcagctct
    69901 tgaccatagc ccgagtcttt ctggctattc caaagattct tatcttagac gaggcaactt
    69961 cttccattga tacacggaca gaagtgctgg tacaggatgc ctttgcaaaa ctcatgaagg
    70021 gccgcacaag cttcatcatt gctcaccgtt tgtcaaccat tcaggatgcg gatttaattc
    70081 ttgtcttagt agatggtgat attgttgaat atggtaacca tcaagaactc atggatagaa
    70141 agggtaagta ttaccaaatg caaaaagctg cggcttttag ttctgaataa gccattctct
    70201 tttgaaagtt tatggacgaa aaaagttgcc ttcgagtgac ttttttgtta caatagctag
    70261 aaaaattgtt cactgtaata ctcaatgaaa atcaaagagc aaactaggaa gctagccgta
    70321 ggttgctcaa agcacagctt tgaggttgta gataagactg acgaagtcag ttcaaaacac
    70381 tgttttgagg ttgcagatag aactgacgaa gtcagctcaa aacactgttt tgaggttgca
    70441 gatagaactg acgaagtcag taaccacacc tacggcaaag tgaatctgaa gtggtttgaa
    70501 gagagtacaa cttgtctttt aaaaaaggag tctataatga aagtctttca gcatgtaaat
    70561 atcgtgactt gtgatcaaaa tttccatgtt tatcttgatg gaatcttagc agtcaaggat
    70621 tctcaaatcg tctatgtcgg tcaagataag ccagcgtttt tagaacaagc tgagcagatt
    70681 atagactatc agggagcttg gattatgcct ggtttggtca attgtcacac ccattctgca
    70741 atgacaggtc tgagagggat ccgagatgac agcaatctcc atgaatggct caatgactat
    70801 atctggccag cagaatctga gtttactccc gacatgacta ccaaggcggt caaagaagcc
    70861 ttgacagaga tgctccagtc aggaacaaca acctttaacg atatgtataa tcccattggt
    70921 gtggatatcc agcaaattta tcaggtggtg aaaacttcca agatgcgttg ttatttttct
    70981 ccgactctct tttcttcaga gacagaaaca actgctgaga ctataagcag aactcgatcc
    71041 atcatagatg aaatcttaaa atataaaaat ccaaatttca aggttatggt agcacctcat
    71101 tctccgtata gctgcagtag agacttgctg gaagcgagtt tggaaatggc aaaagagcta
    71161 aatattccgc tccatgtcca tgtggcggag accaaggagg agtcaggaat tatcctcaaa
    71221 cgatacggca aacgccccct tgcttttctt gaagaactgg gttatttaga tcatccgtcc
    71281 gtatttgctc acggggtcga attaaacgag agagaaattg aacgcttggc atcttctcaa
    71341 gtggctatcg cccacaatcc tatcagtaac ctcaaactgg catcaggaat tgctccaatt
    71401 atccagctcc aaaaagcggg agtagcagtc ggaattgcga ctgactcggt tgcttccaat
    71461 aataatctag atatgtttga ggaaggaagg actgcagctc ttcttcagaa gatgaaaagt
    71521 ggggatgcca gccagtttcc aatcgaaaca gctctcaagg tactgacaat cgaaggggct
    71581 aaggtccttg gaatggaaaa tcagatagga agtctggaag tcggcaagca agcagatttt
    71641 ctggtcattc aaccacaagg gaaaattcat ctccaacctc aggaaaatat gctgtctcac
    71701 ctggtttatg cagttaaatc tagtgatgta gatgatgttt atatcgccgg agaacaggtt
    71761 gttaagcaag gtcaagtcct gacagtagaa ctttaaaaga aaaattacga aaaattttaa
    71821 aaaaagtttg caaaaatctt gcattctttt tttgactatg ctatacttat atacggttta
    71881 aaaaaactgc ctaagacagt aggggagctc gactcataaa tatcctaccg aggacaaaac
    71941 gtatcatgta aaaagaagcg tattgtactt tcgtgtctag gtttgggcgc gtttttcttt
    72001 ttgaaaaatt ccccaagcaa aataattacg gaggtgaaca cactaatgag tgaagcaatt
    72061 attgctaaaa aagcggaact agttgacgta gtagctgaaa aaatgaaagc tgctgcatct
    72121 atcgtcgttg tagacgctcg tggtttgaca gttgagcaag atacagttct tcgtcgtgag
    72181 cttcgtggaa gcgaagttga gtataaagtt attaaaaact caatcttgcg tcgtgcagct
    72241 gaaaaagctg gtcttgaaga tcttgcatct gtatttgttg gaccatctgc agtagcattt
    72301 tctaatgaag atgttatcgc accagcgaaa atcttgaacg acttttctaa aaacgctgaa
    72361 gcacttgaaa ttaaaggtgg tgcaatcgaa ggcgctgtcg catctaaaga agagattctt
    72421 gcacttgcaa ctcttccaaa ccgcgaagga cttctttcta tgctcctttc tgtacttcaa
    72481 gcgccagtgc gcaacgttgc tcttgcagtc aaagcggttg cagaaagcaa agaagacgcg
    72541 gcttaatctt aagctacaca gcgtagccta gctacgaaaa aaactattat aaaatttaaa
    72601 acttatttgg aggaaataac aatggcattg aacattgaaa acattattgc tgaaattaaa
    72661 gaagcttcaa tccttgaatt gaacgacctt gtaaaagcta tcgaagaaga atttggtgta
    72721 actgcagctg ctcctgtagc tgttgctgca gctgatgcag ctgatgctgg tgctgctaaa
    72781 gattcattcg acgttgaatt gacatctgca ggcgacaaaa aagttggcgt tatcaaagtt
    72841 gtacgtgaaa tcactggtct tggtcttaaa gaagctaaag aacttgttga cggtgcacca
    72901 gcacttgtta aagaaggcgt tgcaactgca gaagctgaag aaatcaaagc taaattggaa
    72961 gaagctggag cttcagttac tcttaaataa tagagcaact acattcgtag cttaaaaaca
    73021 tgattaaacc gctattctta ggagtagcgg tttttctttt tgtttaaaaa ggggcaaact
    73081 ttttatatag ttgtttagga aataaataat ttttgtataa ttggtttact actctaaatt
    73141 aacgtagtac aagagtttgt taattaaact ataccttatg gttttgacta gtgtgatata
    73201 attatgttga aatacttatc tggaaaggtt tttataatga gtttaagaaa taaaattgag
    73261 caacatatta aagagctaga gggagggaag tttcaaaaac taggtgacgc gtacctaagt
    73321 agaaaataca attttaatat tgtttcatta ggctcacagg aaggaacaga taaaacaact
    73381 aaagggatcc cagattctta cgctgtcgaa aatggtaaat atgtttatat tatgtatggc
    73441 acccataagt ctgtaatatc taaattagaa ggagacattc agtcagttaa gaaaaaaatt
    73501 ttagaggaaa atattgctga agataaagtt gggagactta tttgttgtca tacttcttca
    73561 aatataacaa ttaaacaaaa agaagatcta gaaaaaatgg ctgagcctta tcatctagaa
    73621 ttgattggaa ttaatgaaat tgctaatgat cttacaaaga tagattttca atatttagca
    73681 aaagagtatc tatcaatcag tgaatctaca gagcaagttt ggtctatcaa tgacttcata
    73741 agaattcatg atgagagtaa aactaatgct cctatatcaa atgactatat tggagatgta
    73801 agtgaaatta taaataccat taaatcaagt gaaaaacgaa tcttcttaat atctgctaag
    73861 cctggaacag ggaaaactag attagcaatt gaaatttgct ctttgctgga tcgaaataaa
    73921 tataacatta tttgtgtcaa gagcaataat caggatattt accaagatgt aaaacgcaat
    73981 ctaaatttac acaaagaaaa tattgttttt attgatgatg ttaatactac acaaaattat
    74041 atttctacac ttgggctact gaacacgact agtaatattc ggtttattct tacggtacgt
    74101 gattatgcta aaaaagatgt aatcaataat attaaagttt atgggtacaa taatattgag
    74161 tcagaactta taaaagatga taattttaag gaattactca atcaattttc tcgaaacgat
    74221 tttaccaatc aagaaattga acatataaaa acgatatcta aaagcaatcc gcgtattgca
    74281 gtcattgcag caaagttatc tagctctcag gatttgacta attttaatga tgagattgat
    74341 attttaaaag attactatga agaaatttta aataaaaaca acattattt
//
LOCUS       DAVLCS010000005        71577 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLCS010000005 DAVLCS010000000
VERSION     DAVLCS010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 71577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71577
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.005"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            <1..566
                     /locus_tag="VXC78_000372"
     CDS             <1..566
                     /locus_tag="VXC78_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582519.1"
                     /translation="LFTKSFATLLIVTNLLSIIHYFGAKNLIVSFNETYPRIQSSVGI
                     MWLPLFGILIIYFIWLLIEGLKYIRKINYIIQNREIIYFYSQVKVVDKLTDSESKKYG
                     EYIDLYESCRQNNLSVLLNFLQNSDDKRGVIASNSVRIMFESLDKADQIAALNICRNY
                     VARENVLNKEDAEKLLNEIDKKLEISR"
     gene            622..1317
                     /locus_tag="VXC78_000373"
     CDS             622..1317
                     /locus_tag="VXC78_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0582520.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            1329..1745
                     /locus_tag="VXC78_000374"
     CDS             1329..1745
                     /locus_tag="VXC78_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0582521.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPIYQRQGIGSALMKEALKDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
     gene            complement(2372..2464)
                     /locus_tag="VXC78_000375"
     CDS             complement(2372..2464)
                     /locus_tag="VXC78_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0582522.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            2625..3596
                     /gene="ruvB"
                     /locus_tag="VXC78_000376"
     CDS             2625..3596
                     /gene="ruvB"
                     /locus_tag="VXC78_000376"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV0582523.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            3685..4149
                     /locus_tag="VXC78_000377"
     CDS             3685..4149
                     /locus_tag="VXC78_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV0582524.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            4380..5138
                     /locus_tag="VXC78_000378"
     CDS             4380..5138
                     /locus_tag="VXC78_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV0582525.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            5147..5950
                     /locus_tag="VXC78_000379"
     CDS             5147..5950
                     /locus_tag="VXC78_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV0582526.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            5972..7231
                     /gene="rseP"
                     /locus_tag="VXC78_000380"
     CDS             5972..7231
                     /gene="rseP"
                     /locus_tag="VXC78_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV0582527.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            7244..9097
                     /locus_tag="VXC78_000381"
     CDS             7244..9097
                     /locus_tag="VXC78_000381"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV0582528.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            9197..10576
                     /gene="bglA"
                     /locus_tag="VXC78_000382"
     CDS             9197..10576
                     /gene="bglA"
                     /locus_tag="VXC78_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0582529.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            10768..12576
                     /gene="glmS"
                     /locus_tag="VXC78_000383"
     CDS             10768..12576
                     /gene="glmS"
                     /locus_tag="VXC78_000383"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV0582530.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYSMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            12695..13744
                     /locus_tag="VXC78_000384"
     CDS             12695..13744
                     /locus_tag="VXC78_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV0582531.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(13844..17641)
                     /gene="spuA"
                     /locus_tag="VXC78_000385"
     CDS             complement(13844..17641)
                     /gene="spuA"
                     /locus_tag="VXC78_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV0582532.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYTSSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTIHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGPVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            18058..18471
                     /gene="rpsL"
                     /locus_tag="VXC78_000386"
     CDS             18058..18471
                     /gene="rpsL"
                     /locus_tag="VXC78_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV0582533.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            18491..18961
                     /gene="rpsG"
                     /locus_tag="VXC78_000387"
     CDS             18491..18961
                     /gene="rpsG"
                     /locus_tag="VXC78_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV0582534.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            19386..21467
                     /gene="fusA"
                     /locus_tag="VXC78_000388"
     CDS             19386..21467
                     /gene="fusA"
                     /locus_tag="VXC78_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV0582535.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPVGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            21571..25962
                     /locus_tag="VXC78_000389"
     CDS             21571..25962
                     /locus_tag="VXC78_000389"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV0582536.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLIMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            26064..26327
                     /locus_tag="VXC78_000390"
     CDS             26064..26327
                     /locus_tag="VXC78_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV0582537.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            26320..26598
                     /locus_tag="VXC78_000391"
     CDS             26320..26598
                     /locus_tag="VXC78_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV0582538.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            26619..26771
                     /locus_tag="VXC78_000392"
     CDS             26619..26771
                     /locus_tag="VXC78_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582539.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            26793..28034
                     /locus_tag="VXC78_000393"
     CDS             26793..28034
                     /locus_tag="VXC78_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV0582540.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            28044..28274
                     /locus_tag="VXC78_000394"
     CDS             28044..28274
                     /locus_tag="VXC78_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0582541.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            28542..29264
                     /locus_tag="VXC78_000395"
     CDS             28542..29264
                     /locus_tag="VXC78_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0582542.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            29481..30815
                     /gene="pepC"
                     /locus_tag="VXC78_000396"
     CDS             29481..30815
                     /gene="pepC"
                     /locus_tag="VXC78_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV0582543.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(30871..31782)
                     /locus_tag="VXC78_000397"
     CDS             complement(30871..31782)
                     /locus_tag="VXC78_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0582544.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(31806..32609)
                     /locus_tag="VXC78_000398"
     CDS             complement(31806..32609)
                     /locus_tag="VXC78_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV0582545.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(32637..33626)
                     /gene="manX"
                     /locus_tag="VXC78_000399"
     CDS             complement(32637..33626)
                     /gene="manX"
                     /locus_tag="VXC78_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV0582546.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYTKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(33859..34878)
                     /gene="adhP"
                     /locus_tag="VXC78_000400"
     CDS             complement(33859..34878)
                     /gene="adhP"
                     /locus_tag="VXC78_000400"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV0582547.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(35217..36029)
                     /locus_tag="VXC78_000401"
     CDS             complement(35217..36029)
                     /locus_tag="VXC78_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0582548.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            36219..37637
                     /locus_tag="VXC78_000402"
     CDS             36219..37637
                     /locus_tag="VXC78_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV0582549.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            37690..38397
                     /locus_tag="VXC78_000403"
     CDS             37690..38397
                     /locus_tag="VXC78_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0582550.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGLVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            38492..39466
                     /gene="folP"
                     /locus_tag="VXC78_000404"
     CDS             38492..39466
                     /gene="folP"
                     /locus_tag="VXC78_000404"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV0582551.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGKFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFGQAFTEEELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            39468..40790
                     /locus_tag="VXC78_000405"
     CDS             39468..40790
                     /locus_tag="VXC78_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0582552.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNVTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            40771..41325
                     /gene="folE"
                     /locus_tag="VXC78_000406"
     CDS             40771..41325
                     /gene="folE"
                     /locus_tag="VXC78_000406"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV0582553.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            41368..42180
                     /gene="folK"
                     /locus_tag="VXC78_000407"
     CDS             41368..42180
                     /gene="folK"
                     /locus_tag="VXC78_000407"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV0582554.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIEKMRNRGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(42225..42542)
                     /locus_tag="VXC78_000408"
     CDS             complement(42225..42542)
                     /locus_tag="VXC78_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV0582555.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            42897..43343
                     /gene="rplM"
                     /locus_tag="VXC78_000409"
     CDS             42897..43343
                     /gene="rplM"
                     /locus_tag="VXC78_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV0582556.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            43362..43754
                     /gene="rpsI"
                     /locus_tag="VXC78_000410"
     CDS             43362..43754
                     /gene="rpsI"
                     /locus_tag="VXC78_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV0582557.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(44015..44437)
                     /locus_tag="VXC78_000411"
     CDS             complement(44015..44437)
                     /locus_tag="VXC78_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0582558.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            44584..44760
                     /locus_tag="VXC78_000412"
     CDS             44584..44760
                     /locus_tag="VXC78_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582559.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            45161..47374
                     /locus_tag="VXC78_000413"
     CDS             45161..47374
                     /locus_tag="VXC78_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV0582560.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFATEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(47596..48072)
                     /locus_tag="VXC78_000414"
     CDS             complement(47596..48072)
                     /locus_tag="VXC78_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV0582561.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQR
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINTFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            48295..51498
                     /locus_tag="VXC78_000415"
     CDS             48295..51498
                     /locus_tag="VXC78_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV0582562.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNREKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRISYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            51878..52263
                     /gene="tnpA"
                     /locus_tag="VXC78_000416"
                     /pseudo
     CDS             51878..52263
                     /gene="tnpA"
                     /locus_tag="VXC78_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(52642..53271)
                     /locus_tag="VXC78_000417"
     CDS             complement(52642..53271)
                     /locus_tag="VXC78_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV0582563.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(53281..54282)
                     /locus_tag="VXC78_000418"
     CDS             complement(53281..54282)
                     /locus_tag="VXC78_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV0582564.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(54313..54954)
                     /locus_tag="VXC78_000419"
     CDS             complement(54313..54954)
                     /locus_tag="VXC78_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV0582565.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(54973..55788)
                     /locus_tag="VXC78_000420"
     CDS             complement(54973..55788)
                     /locus_tag="VXC78_000420"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV0582566.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYTAAKGGLKMLTRNIASEYGEANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            56059..56493
                     /locus_tag="VXC78_000421"
     CDS             56059..56493
                     /locus_tag="VXC78_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0582567.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            56505..57695
                     /locus_tag="VXC78_000422"
     CDS             56505..57695
                     /locus_tag="VXC78_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEV0582568.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            57706..58197
                     /locus_tag="VXC78_000423"
     CDS             57706..58197
                     /locus_tag="VXC78_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0582569.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            58212..58991
                     /locus_tag="VXC78_000424"
     CDS             58212..58991
                     /locus_tag="VXC78_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0582570.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            58978..59796
                     /locus_tag="VXC78_000425"
     CDS             58978..59796
                     /locus_tag="VXC78_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0582571.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            59796..60089
                     /locus_tag="VXC78_000426"
     CDS             59796..60089
                     /locus_tag="VXC78_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0582572.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            60111..62012
                     /locus_tag="VXC78_000427"
     CDS             60111..62012
                     /locus_tag="VXC78_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV0582573.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLIDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKGYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            62072..63073
                     /locus_tag="VXC78_000428"
     CDS             62072..63073
                     /locus_tag="VXC78_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0582574.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(63183..63518)
                     /locus_tag="VXC78_000429"
     CDS             complement(63183..63518)
                     /locus_tag="VXC78_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582575.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(63529..63771)
                     /locus_tag="VXC78_000430"
     CDS             complement(63529..63771)
                     /locus_tag="VXC78_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582576.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(63787..63981)
                     /locus_tag="VXC78_000431"
     CDS             complement(63787..63981)
                     /locus_tag="VXC78_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0582577.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWKEDF"
     gene            64147..65097
                     /gene="rsmH"
                     /locus_tag="VXC78_000432"
     CDS             64147..65097
                     /gene="rsmH"
                     /locus_tag="VXC78_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV0582578.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            65109..65426
                     /gene="ftsL"
                     /locus_tag="VXC78_000433"
     CDS             65109..65426
                     /gene="ftsL"
                     /locus_tag="VXC78_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV0582579.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            65430..67682
                     /gene="pbpX"
                     /locus_tag="VXC78_000434"
     CDS             65430..67682
                     /gene="pbpX"
                     /locus_tag="VXC78_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV0582580.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            67684..68664
                     /locus_tag="VXC78_000435"
     CDS             67684..68664
                     /locus_tag="VXC78_000435"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV0582581.1"
                     /translation="MFISLSAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            69273..71378
                     /locus_tag="VXC78_000436"
     CDS             69273..71378
                     /locus_tag="VXC78_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0582582.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLAAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGGLVIREKS"
BASE COUNT        21100 a        13232 c        16306 g        20939 t
ORIGIN      
        1 ttttatttac aaaatctttt gcaactctat taatagtgac aaatttgtta tccattattc
       61 attattttgg agccaaaaat ttaatagttt cttttaatga aacttatcct cgtattcaat
      121 ccagtgttgg tatcatgtgg ctaccactgt ttggtattct gataatctat tttatttggc
      181 tcttaataga gggattaaaa tatatcagaa aaataaatta tattattcaa aatagggaaa
      241 taatctattt ttattcgcag gtaaaagttg tagataaact tactgattct gaatcgaaaa
      301 aatacggtga atatattgat ttgtacgaat cgtgtcgtca gaacaattta agtgttctac
      361 ttaactttct tcaaaattcg gatgataaac gaggagttat tgctagtaac tcagtgagaa
      421 ttatgtttga atctttggat aaagcagacc aaattgcggc cctgaatatt tgtagaaact
      481 atgtagcacg agaaaatgtt ttaaataaag aagatgcaga aaaattgtta aatgaaattg
      541 ataaaaaact tgaaattagc agataggaca attcaaatag agttgagtaa aaagtttgaa
      601 aagtgaaaca aggagaaagc tatgccagta aatgaatatg gtcagatgat tggtgagtca
      661 atggaaggtt atacacccgg tgcactgcct tctattgatt tcttagaagg gcgttatgct
      721 aggatagagg ctctctcggt agaaaaacat gcggaggatt tgctagctgt ttatggcccg
      781 gatactcctc gggagatgtg gacctatctt tttcaggagc cagtagcaga tatgggggag
      841 ctggttagcc ttttaaatca gatgttggct cgtaaggacc gtttttacta tgcaatcata
      901 gacaaggcga ctggtaaggc tttgggaact ttttctctca tgcgcattga ccagaataac
      961 cgagtaatag aagtcggagc agtcactttt tctccagagc taaggggtac acggatagga
     1021 actgaggctc agtatctcct agctcgctat atttttgagg agctaaacta tcgtcgctac
     1081 gagtggaaat gcgatgcctt aaatctgcca tccagacgag ttgcggagcg tttgggattt
     1141 gtctatgaag gaaccttccg ccaggcggtg gtttataagg ggcgtacgag agatacggat
     1201 tggttgtcta tgattgatat ggactggcct caagtcaaag atcgtttgga aacatggctg
     1261 cgtcctgaaa attttgataa aaatggacag cagtacaaga gcttgagaga actttaagag
     1321 gtgttgagat gattactatt aaaaagcaag aaattgtcaa gctagaggat gttttgcatc
     1381 tctatcaggc tgtcggttgg acaaattata cccatcaacc agagatgctg gagcatgcct
     1441 tatcgcattc attagtaatt tatctggcac ttgatggtga tgctgtggtg ggcttgattc
     1501 gtttggttgg agatggattc tcatcagttt ttgtacagga tttgattgtt ttaccaatct
     1561 atcagcgtca agggattggt agtgccctaa tgaaagaggc cttaaaagat tacaaagatg
     1621 cttatcaagt ccagctggtg acagaagaga cagaaaaaaa cgtgggattt tatcgttcta
     1681 tgggctttga aatcttatcc acctataatt gtatagggat gacttgggcg aatcgagaaa
     1741 aataacaaaa cttgtttttt cttaagcaaa atttaaggat ggtctagtat tatatagtca
     1801 ttaaataaag acctcctaac tttatttaat aaaatcctaa acttttcttt ttcataataa
     1861 tctcccttaa ctccacccaa tcaggtggag ttttttagct ctatttcagg cttttgggga
     1921 ctattctaaa aataattttt cgatattttt cggtattttt cggattttgg tcggggaatt
     1981 ggcggggact tttttagcga atataactaa gaaataggtc tgtggtcgct tcagctagtt
     2041 caaactcaat ttgattgtaa gtgactgtta attgaagaac tggaactact gtaataatga
     2101 ttttgcttgt ctagtagtgg cgtattaaat gagaagtgac atgtaagatt gtctcttcgt
     2161 ttacgaaatc aaaatttcta tgaaattgat agaatcccta acgttctctt aatcttaacc
     2221 gtcttgtcgt acagcggttg aagaaaatgt aaacctttga caaaattcgt gaactatggg
     2281 ataataaaaa ggaattgagt actagttcta tatcataggc tagaaaagac cccaagctca
     2341 cgaccaaata agcttggggt cttttttgac actatttgtc cttgtttagc catttatcga
     2401 ctatacgaag aacgacaccg accacaattg gtccgatgat agttttgagt actaattcca
     2461 tcatgggcta tctcacctcc tttcgtaggc ggtgtagcag tgtcgtagaa tattatacca
     2521 cataagtgct aaacttagga gtcacccaat caggtggctt ttttgtttgt ggcttggttt
     2581 tttgatataa tagagccatg agtagaattt tagataatga gataatgggg gatgaggagt
     2641 tagtagaacg cacgctccgt cctcagtatt tacgtgaata tattgggcag gataaggtta
     2701 aggaccagct tcaaatcttt atagaagctg ccaaaatgcg agatgaagcg ctggatcatg
     2761 tcctcttatt tgggcctcca ggtttgggga aaacaaccat ggcttttgtc attgccaatg
     2821 aactgggagt caatctcaag caaacgtctg gtcctgttat cgaaaaagcg ggtgatttgg
     2881 tagcgatttt gaatgagtta gagcctggag atgtcctctt tattgacgag attcatcgct
     2941 tacccatgtc agtggaagaa gtgctttata gtgccatgga ggacttctac atcgatatta
     3001 tgattggggc tggtgaaggc agtcgcagtg ttcatttgga gttgcctcct tttaccttga
     3061 ttggtgcgac gactcgggct ggtatgctct caaatccact acgggcacgt tttgggatta
     3121 caggtcatat ggagtattat gcccatgctg acttgacaga aattgtcgag cggacggcag
     3181 atatttttga gatggaaatc actcatgagg cagcatctga gttggcccta cgtagtcgtg
     3241 gaacccctcg tattgccaat cgtctcctca agcgcgtgcg cgattttgcc cagataatgg
     3301 ggaatggggt aatcgatgat attattaccg ataaggcttt gactatgctg gatgttgacc
     3361 atgaaggttt ggactatgtg gatcaaaaaa tccttcgtac catgattgag atgtacagtg
     3421 gaggacctgt tggtctagga actctttctg tcaatatcgc cgaagagcgt gagacagttg
     3481 aagacatgta tgagccttac ttgattcaaa aaggttttat catgcggaca cggtctggac
     3541 gggtggcgac tgctaaggca tatgagcact taggttatga atacagtgaa aaataagcaa
     3601 gaaatcttag aggcttttag agaaaatcca gatatgatgg ccattctgac gatcatccga
     3661 gaccttggtt tgaaagactc gtagttggca gcaggttctg tcagaaattt catctggaat
     3721 cttttgtcag acaaatcccc ttttgatcat gaaacagata tagatgtgat tttctttgat
     3781 ccagattttt cttatgagga aaccttatta ctggagaaaa agctgagaga ggattttcct
     3841 cagtaccagt gggaattgaa aaatcaggtc tatatgcatc agcacagtcc tcacactgct
     3901 tcctatacca gttctcgtga tgctatgagt aagtatccag aacggtgtac ggcagttgga
     3961 ctgcgcttga atgaagaatc agattttgaa ctctatgcac cttatggttt ggaggatatt
     4021 ttgaattttc aagttcgtcc aactcctcat ttcttagaaa atgaagaccg aatggaactc
     4081 tatcaaacac gtttatccaa gaaaaattgg caggagaaat ggaaaaattt gatttttaaa
     4141 aatacttaag gaaactttaa gctagggagt gtacactaag ttcataagtt aagaagacct
     4201 taacttaaac tcctaaaact ttttcataat aatctcccta taaaaataaa gtcgcccaat
     4261 caggcggctt atttttttga aaaatgggca tggtgcctga gaataaatag cttagtgata
     4321 gaagaaaatg gggaaatatg gtataatgaa acgatagatt tttgaatagg aataagatca
     4381 tgtttggatt ttttaagaaa gataaggctg tggaagtaga ggttccgaca caggttcctg
     4441 ctcatatcgg catcatcatg gatggcaatg gccgttgggc taaaaaacgt atgcaaccgc
     4501 gagtttttgg acataaggcg ggcatggaag cattgcaaac cgtgaccaag gcagccaaca
     4561 aactgggcgt caaggttatt acggtctatg ctttttctac ggaaaactgg acccgtccag
     4621 atcaggaagt caagtttatc atgaacttgc cagtagagtt ttatgataat tatgtcccgg
     4681 aactacatgc gaataatgtt aagattcaaa tgattgggga gacagaccgc ctgcctaagc
     4741 aaacctttga agctttaacc aaggctgagg aattgactaa gaacaacaca ggattgattc
     4801 ttaattttgc tcttaactat ggtggacgtg ctgagattac acaggcgctt aagttgattt
     4861 cccaggatgt tttagatgcc aaaatcaacc caggtgacat cacagaggaa ttgattggta
     4921 actatctctt tactcagcat ttgcctaagg acttacgaga cccagacttg attatccgta
     4981 ctagtggaga attacgtttg agcaatttcc ttccatggca gggagcctat agtgagcttt
     5041 attttacgga caccttatgg cctgattttg acgaagcggc cttgcaggaa gctattcttg
     5101 cctataatcg tcgtcatcgc cgatttggag gagtttagga ggaaatatga cccaggattt
     5161 acagaaaaga accttgtttg cagggattgc cctggctatt ttcctaccaa ttttaatgat
     5221 tgggggcctc ttgcttcaga tagcaatcgg aatcatagcc atgctagcca tgcatgaact
     5281 tttgaagatg agaggtctag agaccatgac gatggagggc ctcttgaccc tctttgcaac
     5341 ctttgcattg accattccct tggagaatta cctgactttt ttgccagttg atgggaatgt
     5401 ggttgcctat agtgttttga tttcaatcat gttaggaacg accgttttta gcaagtctta
     5461 tacgattgag gatgcggttt tccctcttgc tatgagcttc tacgtgggct ttggatttaa
     5521 tgctttacta gatgctcgtg ttgcaggttt ggacaaggct ctcttagcct tgtgtatcgt
     5581 ctgggcgaca gacagtggtg cctatcttgt tgggatgaac tatgggaaac gaaagttagc
     5641 accaagggta tcgcctaata aaacccttga gggtgccttg ggtggtattt taggagcaat
     5701 tttagtaacc attatcttta tgatagttga cagtacagtt gctcttccat atggaattta
     5761 caagatgtca gtctttgcta ttttctttag cattgctgga caatttggtg atttactaga
     5821 aagttcgatc aaacgtcatt ttggtgttaa ggattctggg aaatttatcc ctggacatgg
     5881 tggtgttttg gatcgtttcg atagtatgtt gcttgtattt ccaatcatgc acttatttgg
     5941 actcttttaa tcaaaagacg gaggaaacgc tatgctcgga attttaacct ttattctggt
     6001 ttttgggatt attgtagtgg tgcacgagtt cgggcacttc tactttgcca agaaatcagg
     6061 gattttagta cgtgaatttg ccatcggtat gggacctaaa atctttgctc acattggcaa
     6121 ggatggaacg gcctatacca ttcgaatctt gcctctgggt ggctatgtcc gcatggccgg
     6181 ttggggtgat gatacaactg aaatcaagac aggaacgcct gttagtttga cacttgctga
     6241 tgatggtaag gttaaacgca tcaatctctc aggtaaaaaa ttggatcaaa cagccctccc
     6301 tatgcaggtg acccagtttg attttgaaga caagctcttt atcaaaggat tggttctgga
     6361 agaagaaaaa acatttgcag tggatcacga tgcaacggtt gtggaagcag atggtactga
     6421 ggttcggatt gcacctttag atgttcaata tcaaaatgcg actatctggg gcaaactgat
     6481 taccaatttt gcaggtccta tgaacaattt tatcttaggt gtcgttgttt tttgggtttt
     6541 aatctttatg cagggtggtg tcagagatgt tgataccaat cagttccata tcatgcccca
     6601 aggtgccttg gccaaggtag gagtaccaga aacggcacaa attaccaaga ttggctcaca
     6661 tgaggttagc aactgggaaa gcttgatcca agctgtggaa acagaaacca aagataagac
     6721 ggcaccgact ttggatgtga ctatttctga aaaggggagt gacaaacaag tcactgttac
     6781 acccgaagat agtcaaggtc gttaccttct aggtgttcaa ccgggggtta agtcagattt
     6841 tctatccatg tttgtaggtg gttttacaac tgctgctgac tcagctctcc gaattctctc
     6901 agctctgaaa aatctgattt tccaaccgga tttgaacaag ttgggtggac ctgttgctat
     6961 ctttaaggca agtagtgatg ctgctaaaaa tggaattgaa aatatcttgt acttcttggc
     7021 aatgatttcc atcaatattg ggatttttaa tcttattccg attccagcct tggatggtgg
     7081 taagattgtg ctcaatatcc tagaagccat ccgccgcaaa ccattgaaac aagaaattga
     7141 aacctatgtc accttggccg gagtggtcat catggttgtc ttgatgattg ctgtgacttg
     7201 gaatgacatt atgcgactct tttttagata atcgaggaat attatgaaac aaagtaaaat
     7261 gcctatccca acgcttcgcg aaatgccaag cgatgctcaa gttatcagcc atgctcttat
     7321 gttgcgtgct ggttatgttc gccaagtttc agcaggtgtt tattcttatc taccacttgc
     7381 caaccgtgtg attgaaaaag ctaaaaacat catgcgccaa gaattcgaaa agattggtgc
     7441 tgttgagatg ttggctccag cccttcttag tgcagaattg tggcgtgaat caggtcgtta
     7501 cgaaacctat ggtgaagacc tttacaaact gaaaaaccgt gaaaaatcag actttatctt
     7561 aggtccaact cacgaagaaa cctttacagc tattgtccgt gattctgtta aatcttacaa
     7621 gcaattgcca ctcaaccttt atcaaattca gcccaagtat cgtgatgaaa aacgcccacg
     7681 taatggactt cttcgtacac gtgagtttat catgaaggat gcttatagtt tccacgctaa
     7741 ctatgatagt ttggatagtg tttatgatga gtacaaagca gcctatgagc gtattttcac
     7801 tcgtagtggt ttagacttca aggctattat tggtgacggt ggagccatgg gtggtaagga
     7861 tagccaagaa tttatggcca ttacatctgc tcgtacagac cttgaccgct gggttgtctt
     7921 ggacaagtca gttgcctcat ttgacgaaat tcctgcagaa gtgcaagaag aaatcaaggc
     7981 agaattgctc aaatggatag tctctggtga agataccatt gcttactcaa gtgagtctag
     8041 ctatgcagct aacttagaaa tggcaacaaa cgagtacaaa ccaagcaacc gtgttgtcgc
     8101 tgaagaagaa gttactcgtg ttgcaacgcc agatgttaaa tcaattgatg aagttgcagc
     8161 tttcctcaat gttccagaag aacaaacgat taaaaccctc ttctacattg cagatggtga
     8221 gcttgttgca gcccttctag ttggaaatga ccaactcaac gaagtcaagt tgaaaaatca
     8281 cttgggagca gatttctttg acgttgctag cgaagaagaa gtggcgaatg ttgttcaagc
     8341 aggatttggt tcacttggac cagttggttt gccagagaat attaaaatta ttgcagatcg
     8401 taaggtgcaa gatgttcgca atgcagttgt cggtgctaac gaagatggct accacttgac
     8461 tggtgtgaac ccaggccgtg attttactgc agaatatgtg gatatccgtg aagttcgtga
     8521 gggtgaaatt tccccagatg gacaaggtgt ccttaacttt gcgcgtggta ttgagatcgg
     8581 tcatattttc aaactcggaa ctcgctactc agcaagcatg ggagcagatg tcttggatga
     8641 aaatggtcgt gctgtgccaa tcatcatggg atgttacggt atcggtgtca gccgtcttct
     8701 ttcagcagtg atggagcaac acgctcgcct ctttgttaac aaaacgccaa aaggtgaata
     8761 ccgttacgct tggggaatca atttccctaa agaattggca ccatttgatg tgcatttgat
     8821 tactgtcaat gtcaaggatg aagaagcgca agccttgaca gaaaaacttg aagcaagctt
     8881 gatgggagct ggttatgaag tcttgacaga tgaccgtaac gaacgtgtcg gtgttaaatt
     8941 tagcgatagt gacttgattg gtcttccaat ccgtatcact gttggtaaaa aagcggccga
     9001 tggcattgta gaagttaaga tcaaggcaac tggtgacacc attgaggttc atgcagataa
     9061 cgtgcttgaa acgcttgaaa tcctaagcaa gaaataaaaa ctataatcag aagaaaaaca
     9121 aggaaaaaat gtaactagtt tttaccttgt tttttctgta taatgggaga aatgagtaga
     9181 taaagaggta aatgttatgc taagatttcc aaaggatttt gtctggggat cctctacttc
     9241 tggaccgcag acagaaggac gtgtagctgg tgacggtaag ggagacaatc tctgggatta
     9301 ctggttccaa gtggagccaa atcgttacta taatgggatt ggttcagata agacatcgac
     9361 tttttatgaa aattgggagc gggatattga gcttttgtta gagactggtc acacagtctt
     9421 tcggacttct attcagtggt cacggatttt tccacaaggc tgtggaaaag tcaaccctca
     9481 aggtgtggat ttttatcgta aggtctttga ggctattaag gctaaaggaa ttcgtctgtt
     9541 agtcaatctc tatcattttg atttaccttt tgcccttcaa gaggatggtg atggttggga
     9601 aaataaggcg acagtctcag cctatgaaga ctatgctcgt ttttgttttg agacttatgg
     9661 agatttagtg gatcaatgga ttacctttaa cgagcccatc gttcctgtag aatttggtta
     9721 tttttatgat gcccattatc cacataaggt ggatgcagag gcagctgtta aggtagccta
     9781 tcatacacaa ttggccagca gccgggctgt taaggcttgc catgaacttt tgcctgattc
     9841 caagattggg attgtcctca acttgacacc ggcttatcca cgtagccagc atcctgctga
     9901 tgtcaaggca gctcgtattg cggccctttt tcaggcccaa tctttcttag atccatctgt
     9961 cttggggact tatccacagg agttggtaga aatcttgcat gaacacggtc ttttacctga
    10021 tgctacagag gaagagttgg aactcattcg tgataatacg gtggacttcc ttggtgtgaa
    10081 ctactatcaa cctttgcgtg ttatggctcc tcgatttgct aagcatccag atagtccact
    10141 cttaccagaa catttttacg agccttatgt gatgcctgga cgtaaaatca attctcaccg
    10201 tggttgggag atttatgagc aagggattta tgacatcgcc caaaatatca aggaaaatta
    10261 tggcaatatt gagtggatgt tgactgagaa tggtatgggt gttgaagggg aagaaaaatt
    10321 ccgtcaagat ggaatgattc aagatgatta ccgtattgac tttgtaaaag gtcatcttcg
    10381 tgaacttcac cgtgccattg aagatggtgc caactgtaag ggctacttga tttggacctt
    10441 tattgactgc tggtcatggc tcaacagcta taaaaatcgc tatggtttgg tcgaattaga
    10501 cttggaaacg caagaacgtc gtctgaagaa atcaggccac tggttcaaag aattaagcga
    10561 taataatgga ttttaaaaag gactctgact gattatccca atcggtcaga gttttttgct
    10621 tacaggagct taatttgaac tataccaatt tttactcttg acaagtgaaa gaaacaagta
    10681 tatactgttt ttgctgattc tataaaagat gaattagact ataccaattt taaggagaaa
    10741 gcacagcttg cctgtgtcgt atatactatg tgtggaattg ttggtgttgt tggaaacaca
    10801 aatgcaactg atattttgat tcaagggctt gaaaagcttg aataccgtgg ctatgattct
    10861 gcgggaattt ttgtcctaga tggtgctgat aaccatttgg tgaaggcggt tggtcgtatt
    10921 gcagaattgt ctgccaagac agctggtgtt gagggaacaa ctggtatcgg acatactcgt
    10981 tgggctactc acggaaaacc aactgaggac aatgctcacc cacaccgctc tgagacagaa
    11041 cgttttgtct tggtgcataa tggggtgatt gagaactatc ttgaaatcaa ggaagaatac
    11101 cttgcaggtc accacttcaa ggggcagaca gatactgaaa tagccgttca tttgattgga
    11161 aaatttgcgg aagaagaagg gctctcagtt cttgaagcct tcaaaaaagc ccttcacatc
    11221 atccgtggtt cttatgcctt tgccttggtt gactcacaag atcctgaagt catctacgta
    11281 gctaaaaata aatcaccact tttgattggt cttggagaag gctataacat ggtctgctca
    11341 gacgccatgg ctatgattcg tgaaactaac caatacatgg aaatccatga ccaagagttg
    11401 gtaatcgtca aggctgatag tgtggaagtt caagactatg atggaaatcg tcgtgagcgt
    11461 gctagctaca ctgctgagct tgacttgtca gatatcggta agggaactta cccttactac
    11521 atgctcaagg aaattgacga gcaaccaact gttatgcgga aactcatcca agcctacaca
    11581 gatgaggctg gtcaagttgt cgtggaccca gatatcatta aggctgttca agacgcagac
    11641 cgcatctaca tccttgcagc tggaacatct taccatgcag gatttgcttc taagaaaatg
    11701 ttggaagaat tgacagatac accagttgaa cttggaatct catctgagtg gggctacagt
    11761 atgccacttc tcagcaagaa accactcttc atctttatca gccaatctgg tgaaacagcg
    11821 gatagtcgtc aagttttggt caaggctaat gaaatgggaa ttccaagctt aacagtgaca
    11881 aacgttccag gttcaaccct ctcacgtgaa gccaactata ccatgctcct tcacgcaggt
    11941 cctgaaattg ccgtggcatc aactaaagcc tatacagcgc aaatcgcagc ccttgccttc
    12001 cttgcaaaag cagtcggaga agcaaatggt aatgctaaag cgcaagcctt tgacctggtt
    12061 catgaattgt caatcgtagc tcagtctatc gaatcaactc tttcagagaa agaaaccatt
    12121 gaagccaagg ttcgtgaact tcttgaaaca actcgtaacg ccttttacat cggacgtggt
    12181 caagattact acgtagccat ggaagcaagt ctcaaactca aagagatttc ttatatccag
    12241 tgtgaaggtt ttgcggcagg agaactcaag cacggaacca ttgccttgat tgaagaagga
    12301 acgcctgttt tggctctctt gtcagatcca gttcttgcca accatactcg tggaaatatc
    12361 caagaggtcg cagcccgtgg tgccaaagtc ctcactatcg cagaagagaa tgtagccaaa
    12421 gataccgacg atatcgtcct tacgaccgta catccatacc tctcaccaat ttcaatggtc
    12481 gtaccaacgc aattagtcgc ttactttgca accctccacc gtggcctcga tgtggataaa
    12541 ccacgtaacc ttgctaaatc agtaacggta gaataagcta aaaaagtcta gttatctagg
    12601 ctttttctaa tgagcaaatt ggttgcttgt acttaagatt cgtgttagaa taatttttca
    12661 aattgaagga cagagataga caaggagaat cacaatggta gaattgggaa tttcaacatt
    12721 tggggaaata acggagcttg aagggactgg acaaacttac agtcatgctg aacgcattcg
    12781 ccagttggtg gcagagattg agctggctga caaggttggt ttggatgtat atgggattgg
    12841 tgagcaccat cgggcggatt ttgcagtatc agccccagag attgttctgg ccgctggggc
    12901 agtcaatacc aagaaaatcc gtttgaccag tgcagtcagc attctgtcaa gcatggaccc
    12961 gattcgtttg ttccaacagt atgccactat cgatgctttg tcaaatggac gagcggagat
    13021 tatggctgga aggggctctt tcacggaatc tttccctctg tttggttatg acttgaaaga
    13081 ctacgactct ctttttgatg agaaattaga cttgcttcag ttagtcaatg aaaagaccaa
    13141 gttagactgg caaggtcgat tgactcaaac gattgctggt aaagaagttt atcctcgtcc
    13201 agttcaggac aaattgccct tgtggatagc tacaggtggt catgtcgaat caacagtgaa
    13261 gattgctcag gctggtctac cgattgtata tgctattatt ggtggtaatc cacgttattt
    13321 taaaaagttg attcaggctt atcgtgagat tggaagcgaa gcgggtcatg ctgacaaaga
    13381 cttgaaagtg ggagcccatt cttgggggtg gattgcggaa gatggtgagc aggcggtgaa
    13441 agattatttc catccgacta agcaagtggt ggatgctatt tccaaagacc gtccgcactg
    13501 gcaggaattg cgttatgagc aatatttgga gcaggtaggg ccaaatggcg ccatgtttgt
    13561 tggcaatcca gatcaggtgg ccgaaaaatt gattcgcatg atagaggatt taggattgga
    13621 ccgcttcatg cttcatctac cgcttggttc tatgcctcat gaccaggttc tgagagctat
    13681 tgaactcttc ggaacacaag ttgcacccaa agtacgagct tattttgcta tgaaagaggc
    13741 ttaataaaaa atcctaatca agtttattag gacaacaaat attgtacgaa aattaatccc
    13801 ccgagctata atgcttgggg gatttttcta taggagggct agtttagttc tcttttttat
    13861 tttttagtaa gaaaccgaga ccaaggagcg caaggaggct gattcctgca aataggagtt
    13921 tgttttcgtt tttgattcct gtatttggaa gttcagcttg tttatctggg gttgcaggta
    13981 tattttcctt gctagagttt tctaccgatt cgtttcgaac cgcttctttt acagatgatg
    14041 cttgtgcttc ttgtgctggt tgttcagctt gtgaatcagc tgtagcttgg ctaggtttat
    14101 tttccgcatc agctactttg gcatctggtt tagtagaatc aggtctagct tctggagctg
    14161 ggtcttgatg tgcagggtga gaagcttcat tttgatgttc aggcttggaa ggggttgagt
    14221 ctggtttctc ttctgcagtt gactcatggc tagttccatt ttgagagact cgaagaacag
    14281 tagctgtaag ggcattcaat ttcaagcctt tttcagtcca ttcaagtcct ttcgggttgg
    14341 caattccgac tggtcctgct tggttttcat ctgccaaaac ttccgcattt cttagatgtg
    14401 caaaggcagt tcccaaatta aattcgcgag ctttttcatc cgcattgaca aagactgcgt
    14461 agatatcgcc gtttggagca gtgatttggt agccaatcac tacatcctct ttttccacac
    14521 cattttggcc tgggacagtg atgaggtgga cacggtcttt gatatcttgg agactcttaa
    14581 gtcggaaggc atctgtagat tgacgaaggg caatcaaacc tttcatatag tcacggctct
    14641 tgacattttc aggataagct ttaccatctg tagccttagt ccagtcaaac ttgttgactg
    14701 cgtcgctaga atcgtaagaa tcatggatga agtaaggata gtcaaatggg ttgccgtcct
    14761 tatcacgtaa caagtgagat ttgtttggaa ccttatcctc tgctactgga gtcttgtagg
    14821 ctgggtcacg gaattgttta gtacgtccat attcctgacc ggagtggata aatggagttc
    14881 cttgagctgt caagaccatg agatttccaa gtcgtaaacg acggtggatt tcagcatagt
    14941 tctcagcctt gcttgggtct tttttgatag actgggcaat gatgtcaaag agggtcaagt
    15001 tatcatgggc tgctatgtat tggatgacat ctccagggct gtcagcttca aagttagttg
    15061 gttgagcaat gagattttta aagatggtgt tgacatcacg cttgccacct gtgataaagg
    15121 caggttgacc ttcgtttgga taaccagatt tgaggttgtt acggatgtca tctgaaaaga
    15181 cagcgacagt atcggtatgt ttcatccaat cttggtcagc agctttagta ggcatgtttt
    15241 catcaccggc ataggttctc caaccttcac caagcatgat gaggtttgga ttgagggcgc
    15301 gtgcagcctt gtaagcttct tcgatagaag cggcgtcatg gtctcccatc atatcgaaac
    15361 ggaatccatc cactttgtag gtatcaacta ggtatttgat agagtcaact aggagccgtt
    15421 tggtcatatg gtggattgtt cccaagcgtc caccaccaaa gctagttcga ggtgtgccat
    15481 cggcatccat aaagtggtag tagtttggct ctaggtcttc aaagatatcg actttggctg
    15541 tgtggttata aacgacatct aggatagctc ccataccacg tttgtggatt tcgttgatga
    15601 ggtttttaaa ttctgcgatt cgtttttctg gattcttagg atcgcttgag tacataccag
    15661 tcaaggagaa gtagttttga gggtcatatc cccagttgta gttgctgttg cttgaagtgt
    15721 agtcagacaa gcgttcatgg tttttcaatt cattgacaaa gtagtaagac aagactggaa
    15781 ggagctggat atgggttaca cccaagtctt tgagatagtc tagtttttca atgaaggctt
    15841 caaaagtccc aaatggtttg gtcaagtctt ttgcaatggc aggatctgaa gtgaagtcac
    15901 gcacatgagc ttcgtagata acggcgtctt cacgagtctt gaaattgtga atcttaccat
    15961 aagtcaagtc ttgaggtccg agtttagctg gatctacaaa ggcggcttta gccactttat
    16021 gggcatcgtc aattttggca tcgtcgctat tccaagcagc aagagattta gcgtaaggat
    16081 cgagtgcaag aacagtttta ccttgacgct cgatttggta ttgataatag tagccagtga
    16141 aatctgtgat tccgagtttg tttgtgctgt ctagagtttg tttccaagtt cctctttccc
    16201 ctttttcgag agcgacagtt ccaactactt tgtcagggtc attcttgtcg tagacaacaa
    16261 cagaaacctt atcagcactt ggtgaccaaa gggtcaaatc aacttgtttt ccttcttctt
    16321 ttaggtcagc tcccagtttg ccatcatagc tgtatgtctc atctttcagg cgccagcttg
    16381 ttttggtagt gaattggtcg gaattgtagc taacagtata aggatgtttt gtgtcagaga
    16441 aatctccgct gtaggtcact ttcttaccag cttcatcgat tgcaacatcg gtaatagtta
    16501 ccttgtttcc taggtgatta gtgatgttgg agtgtttgag gatatcttct tttttagcac
    16561 cgacaagtgt tgaaaagcta ctttcaatgc tagaagtgcc tacgtgttgg gctcctgtca
    16621 tacggatatc atggacatag tatggatttg tgtaaatcga ttcatcatcg tcttttagga
    16681 aaatttggct atgatttttc aaatctgtga acttataatt ttctttacgg attttcacgt
    16741 cgtctccttg tttgctctca tctagtaata aaaatccaaa ttctcttgcg gcttcattaa
    16801 gaggaatgtc gatatagcgg ccatatttgc ctgtagccgt aaagtctgtt ccgtcaggcc
    16861 attgagcgct acttggattt tttacatctc cccagtacca gagagatttc ttgtcatagt
    16921 tgccatctgt gcggtagtag ttgacgcgaa cagttcctgc aggctgtggc tcgtaagaga
    16981 aaaccttgta atcttggtct aaccaagctt cgttcatttt tggaactagt ttttctacag
    17041 atttatcgcc ggttagattt tttccagctg tattgttgat gaggaagcta attttcttgg
    17101 cttgttctcc ctttaatttg acatctaggt aatagccgta gtcatctttc ttggcatcct
    17161 tgaaggacaa agctccgttt ggccagtttt cagatggttt ttcaacatcg tcccaagtcc
    17221 atagtccttg agcatccttg ttttcttcag gaagtttttt gacatggata cggaagtagt
    17281 tatcttcgat gggctcttct gccttagttt cagttgttac tggactagta gaagtagttg
    17341 gctctgttgc aggtttttct tctgttttct ctagggaagc gtttgcattt ctaggtgaag
    17401 aaatatcact ttcgttctta ccagagccag ctgctgtatc agtaagaggt tgggcaaggg
    17461 tggttgtatt tctgttgttg ggttcgttag tggttggtgt actttcgtcg gatgagatag
    17521 ttggtgtagc catggcaagc aagacaaggc ttgcgccgat aaggacagaa ccagttccat
    17581 ttttgaggga acggatgctg tagaccattt ttttctcagt gtgagatggt gtttttctca
    17641 taatgattct ccaatcaata aatttctata tcagtatagc atgtagtaaa acaatatgca
    17701 agcgttttct ttgatttgtg aaaaaaattc ttacttttga gaagttttct gtactatttt
    17761 atatatcagt ataaatgacg gagataaaaa tgtcacataa gccaagccgt attattagga
    17821 agatgatgtg ttcccagcta tttttattca gaaattgatc tctaacatta ccaataaaaa
    17881 agaaaaatat cttgacaagc aagggaaaat tttgttacaa taatagacgg tactttttac
    17941 ttttggtctc tcaagagtgt acagggacgt gctgacaaat gttgcaaaag tacacacaga
    18001 tgatatctgt caccaagtgt atcatcacca aaaataaaaa aacacaggag aatgtagatg
    18061 cctacaatta accaattggt tcgcaaaccg cgtaaatcaa aagtagaaaa atctaaatca
    18121 ccagctttga acgttggtta caatagtcat aaaaaagttc aaacaaacgt ttcttcacca
    18181 caaaaacgtg gtgttgcaac tcgtgttgga acaatgacac ctaaaaaacc taactcagcc
    18241 cttcgtaaat tcgctcgtgt acgtttgagc aaccttatcg aagttactgc ctacatccca
    18301 ggtatcggac acaacttgca ggagcacagc gtggtgcttc ttcgcggtgg acgtgtaaaa
    18361 gaccttccag gggtacgtta ccatatcgtc cgtggtgcac ttgatactgc aggtgttaac
    18421 gatcgtaaac aaggccgttc taaatacggt actaaacgtc caaaagcata aggaaagggg
    18481 ataaagagaa atgagtcgta aaaatagagc tccaaaacgt gacgtattgc cagatccgct
    18541 atacaattca caactagtta ctcgtcttat caaccgcgtt atgcttgatg gtaaacgtgg
    18601 tactgctgct tcaatcgttt acggtgcttt tgagcaaatc aaagaagcta ctggcaacga
    18661 tgcacttgaa gtatttgaaa cagctatgga aaacatcatg cctgtacttg aagtacgtgc
    18721 acgtcgtgtt ggtggttcta actaccaagt cccagttgaa gttcgtccag aacgtcgtac
    18781 aacacttgga cttcgttggt tggtaacaat cgctcgtctt cgtggtgaac acacaatgca
    18841 agaccgtctt gcaaaagaaa tcttggatgc tgctaacaac actggtgcag cagttaagaa
    18901 acgtgaagat actcaccgta tggctgaagc taaccgtgca ttcgcacact tccgttggta
    18961 agataggatg cgaaagcgtt aagaaagtcc cagagaaaat agggaatcga agcaggttgc
    19021 ggttgcaacc aatgagattc atctttttct ccagactttt agcttgagct caactaaatc
    19081 atgatgctag gaacggtaag gatgcaaggt gaaaatagga aactgacgca gtattcgacg
    19141 aatacaagga gttttatctt tttcacgcag catcccgttc cagctcacat cggctaacta
    19201 actttagccc gggttcaaat tagctaaatc gattagtatt agctataact cagcttacca
    19261 tctcgtaagt tgaaaccaac aatagcatga aaacattgag aacgggtagg tcctgcctat
    19321 ccgtttttat taaaatcgtg ttataataga atagaaatca aaaataaata ggagaaacaa
    19381 acctcatggc acgcgaattt tcacttgaaa aaactcgtaa tatcggtatc atggctcacg
    19441 tcgatgccgg taaaacaaca actactgagc gtattcttta ctacactggt aaaatccaca
    19501 aaatcggtga aactcacgaa ggtgcgtcac aaatggactg gatggagcaa gagcaagaac
    19561 gtggtatcac gatcacatct gctgcgacaa cagctcaatg gaacaaccac cgcgtaaaca
    19621 tcatcgacac accaggacac gtggacttca caatcgaagt acaacgttct cttcgtgtat
    19681 tggatggtgc ggttaccgtt cttgactcac aatcaggtgt tgagcctcaa actgaaacag
    19741 tttggcgtca agcaactgag tacggagttc cacgtatcgt atttgccaac aaaatggaca
    19801 aaatcggtgc tgacttcctt tactctgtaa gcacacttca cgatcgtctt caagcaaatg
    19861 cacacccaat ccaattgcca gtcggttctg aagatgactt ccgtggtatc attgacttga
    19921 tcaagatgaa agctgaaatc tatactaacg accttggtac ggatatcctt gaagaagaca
    19981 tcccagctga ataccttgac caagctcaag aataccgtga aaaattgatt gaagcagttg
    20041 ctgaaactga cgaagaattg atgatgaaat acctcgaagg tgaagaaatc actaacgaag
    20101 aattgaaagc tggtatccgt aaagcgacta tcaacgttga attcttccca gtattgtgtg
    20161 gttcagcctt caaaaacaaa ggtgttcaat tgatgcttga tgcggttatc gactaccttc
    20221 caagcccact tgacatccca gcaatcaaag gtattaaccc agatacagac gctgaagaaa
    20281 ttcgtccagc atctgacgaa gagccatttg cagctcttgc cttcaagatc atgactgacc
    20341 cattcgtagg tcgtttgaca ttcttccgtg tttactcagg tgttcttcaa tcaggttcat
    20401 acgtattgaa tacttctaaa ggtaaacgtg aacgtatcgg acgtatcctt caaatgcacg
    20461 ctaacagccg tcaagaaatc gacactgttt actcaggtga tatcgctgct gccgttggtt
    20521 tgaaagatac tacaactggt gactcattga cagatgaaaa atctaaaatc atccttgagt
    20581 caatcaacgt tccagaacca gttatccaat tgatggttga gccaaaatct aaagctgacc
    20641 aagacaagat gggtatcgcc cttcaaaaat tggctgaaga agatccaaca ttccgcgttg
    20701 aaacaaacgt tgaaactggt gaaacagtta tctcaggtat gggtgaactt caccttgacg
    20761 tccttgttga tcgtatgcgt cgtgagttca aagttgaagc gaacgtaggt gcgcctcaag
    20821 tatcttaccg tgaaacattc cgcgcttcta ctcaagcacg tggattcttc aaacgtcagt
    20881 ctggtggtaa aggtcaattc ggtgatgtgt ggattgaatt tactccaaac gaagaaggta
    20941 aaggattcga attcgaaaac gcaatcgtcg gtggtgtggt tcctcgtgaa tttatcccag
    21001 cggttgaaaa aggtttggta gaatctatgg ctaacggtgt tcttgcaggt tacccaatgg
    21061 ttgacgttaa agctaagctt tatgatggtt catatcacga tgtcgactca tctgaaactg
    21121 ccttcaagat tgcggcttca ctttccctta aagaagctgc taaatcagca caaccagcta
    21181 tccttgaacc aatgatgctt gtaacaatca ctgttccaga agaaaacctt ggtgatgtta
    21241 tgggtcacgt aactgctcgt cgtggacgtg tagatggtat ggaagcacac ggtaacagcc
    21301 aaatcgttcg tgcttacgtt ccacttgctg aaatgttcgg ttacgcaaca gttcttcgtt
    21361 ctgcatctca aggacgtggt acattcatga tggtatttga ccactacgaa gatgtaccta
    21421 agtcagtaca agaagaaatt attaagaaaa ataaaggtga agactaatcc gtcctcactc
    21481 tagaaggaag tcacttagtg gcttcctttt gtctttagaa aatacctcta aatatggtaa
    21541 aatagtagaa gaataatgtg aggaaaatga atgtcaaata gttttgaaat tttgatgaat
    21601 caattgggga tgcctgctga aatgagacag gctcctgctt tagcacaggc caatattgag
    21661 cgagttgtgg ttcataaaat tagtaaggta tgggagtttc atttcgtatt ttctaatatt
    21721 ttaccgattg aaatcttttt agaattaaag aaaggtttga gcgaagaatt ttctaagaca
    21781 ggcaataaag ctgtttttga aattaaggct cggtctcaag aattttcaaa tcagctcttg
    21841 cagtcctact atagggaggc tttctctgaa ggtccatgtg ctagtcaagg ttttaagtcc
    21901 ctttatcaaa atttgcaagt tcgtgctgag ggtaatcagc tatttattga aggatctgaa
    21961 gcgattgata aggaacattt taagaagaat catcttccta atttagccaa acaacttgaa
    22021 aagtttggtt ttccaacttt taactgtcaa gtcgagaaga atgatgtcct gacccaagag
    22081 caggaagagg cctttcatgc tgaaaatgag cagattgttc aagctgccaa tgaggaagcg
    22141 ctccgtgcta tggaacaact ggagcagatg gcacctcctc cagcggaaga gaaaccagtc
    22201 tttgattttc aagcgaaaaa agctgcagct aaacccaagc tggataaggc ggagattact
    22261 cctatgatcg aagtgacgac agaggaaaat cgtctggtat ttgaaggggt tgtttttgat
    22321 gtggaacaaa aagtgactag aacaggtcgt gttttaatca actttaaaat gacggactat
    22381 acttcaagtt tttctatgca aaagtgggtt aaaaacgagg aagaggccca gaagtttgac
    22441 ctcatcaaga agaattcttg gctccgagtt cgagggaatg tggagatgaa taacttcaca
    22501 cgcgatttga ttatgaacgt acaggatctg caggaagttg ttcactatga gcggaaggat
    22561 ttgatgccag aaggtgagcg tcgggttgag tttcatgctc atactaacat gtcgactatg
    22621 gatgctttgc cagaggtcga agagattgtt gcaacagctg ctaagtgggg acacaaggcg
    22681 gttgctatca cagaccatgg gaatgtccag tcctttccac atggctataa ggcggctaag
    22741 aaagcgggaa tccagctgat ctatgggatg gaagccaata tcgtggagga ccgtgtccct
    22801 atcgtctata acgaagtgga gatggactta tcagaagcaa cctacgtggt ctttgacgtg
    22861 gaaacgacgg gactttcagc tatctataat gacttgattc aggttgcggc ctctaagatg
    22921 tacaagggga atgttattgc tgaatttgat gaatttatca atcctgggca tcccttgtca
    22981 gcttttacta cagagttaac tggaattaca gatgatcatg tcaaaaatgc caaaccacta
    23041 gaacaagttt tgcaagaatt ccaagaattt tgcaaggata cggtcctagt tgcccacaat
    23101 gctacctttg acgttggctt tatgaatgct aattatgagc gtcatggtct tccaaagatt
    23161 agtcagccag ttattgatac gctggagttt gctagaaacc tctatcctga gtataaacgc
    23221 catggtttgg ggcctttgac caagcgtttt ggtgtggcct tggaacatca tcacatggcc
    23281 aactacgatg cggaagcgac tggtcgtctg cttttcatct ttatcaaaga ggtagcagaa
    23341 aaacatggtg tgaccgattt agctagactc aacattgatc taatcagtcc agattcttac
    23401 aaaaaagctc ggatcaagca tgcgaccatc tatgtcaaga atcaggtagg tctaaaaaat
    23461 atctttaagc tggtttcctt gtctaatacc aagtattttg aaggagtgcc acggattccg
    23521 agaacggttc tagatgccca tcgagagggc ttgattttag gttcagcctg ttcagagggt
    23581 gaagtttttg acgtggtcgt ttctcaaggt gtggatgcgg cggttgaggt ggccaagtat
    23641 tatgacttta tcgaggtcat gccaccggct atctatgcgc ccttgattgc taaagagcag
    23701 gtcaaggata tggaggaact ccagaccatt atcaagagtt tgatagaggt tggagaccgc
    23761 cttggcaagc ctgttttggc tacgggaaat gttcactata tcgaaccgga agaagagatt
    23821 tatcgtgaaa ttatcgtccg tagtttggga cagggtgcga tgattaaccg aactatcggt
    23881 catggtgaac atgcccaacc agcaccactt ccaaaggctc attttcgaac gactaatgag
    23941 atgttggatg aatttgcctt tttgggagag gaactggctc gtaaactggt tattgaaaac
    24001 accaatgcct tggcagaaat atttgaaccc gttgaagtcg ttaagggtga cttgtatacg
    24061 cctttcatcg acaaggctga agaaacagtt gctgagttga cctataagaa agcttttgag
    24121 atttatggaa atccgctgcc agatattgtt gatttgcgga ttgaaaaaga attaacatcc
    24181 atactgggga atggatttgc tgtgatttat ctggcatcgc agatgctggt gcaacgttct
    24241 aatgaacggg gttatttggt tggttctcgt gggtctgtcg gatctagttt cgttgcgacc
    24301 atgattggaa ttacggaggt caatcctctc tctcctcact atgtctgtgg tcagtgtcag
    24361 tacagtgagt ttatcacaga tggttcgtac ggttcaggat ttgatatgcc ccataaggac
    24421 tgtccaaact gtggtcacaa actcagtaaa aacggacagg atattccgtt tgagaccttc
    24481 cttggttttg atggggataa ggttcctgat attgacttga acttctcggg agaagatcag
    24541 cctagcgccc acttggatgt gcgtgatatc tttggtgaag aatatgcctt ccgtgcggga
    24601 acagttggta cggtagctgc caagactgcc tatggatttg tcaagggtta cgagcgagat
    24661 tatggcaagt tttatcgtga tgcagaagta gaacgcctcg ctcaaggagc ggcgggtgtc
    24721 aagcggacaa caggccaaca cccgggggga atcgttgtta ttccgaacta catggatgtc
    24781 tacgatttta cgcctgtcca gtatccagca gatgatgtca cggctgaatg gcagaccact
    24841 cactttaact tccacgatat cgatgagaac gtcctcaaac tcgatgtact gggacatgat
    24901 gatccgacca tgattcgaaa acttcaggat ttgtctggta ttgaccctaa taaaattcct
    24961 atggatgacg aaggcgtgat ggcactcttt tctgggactg atgtgctagg ggtaacacct
    25021 gaacaaattg gaacgcctac gggtatgttg gggattccag agtttggaac aaatttcgta
    25081 cgtggaatgg tagacgaaac ccatccgaca acctttgcgg aattgcttca gctgtctggt
    25141 ctgtcccacg gtactgatgt ttggttgggg aatgctcagg atctgattaa gcaaggaata
    25201 gcggacctat cgactgttat cggttgtcgg gacgacatca tggtttacct catgcatgcg
    25261 ggtctggaac ctaagatggc ctttaccatt atggaacggg tacgtaaggg tttgtggcta
    25321 aagatttcag aagaggagag aaatggctat atcgaagcaa tgaaggctaa taaggtgcca
    25381 gagtggtata tcgaatcctg tgggaaaatt aagtacatgt tccctaaggc ccatgcggca
    25441 gcctacgtta tgatggcctt gcgtgtagct tacttcaagg ttcaccatcc tatttattac
    25501 tactgtgctt acttctccat tcgtgctaag gcttttgata tcaagaccat gggtgcgggc
    25561 ttggaggtca tcaagcgcag aatggaagaa atctctgaaa aacggaagaa caatgaagcc
    25621 tctaatgtgg aaatcgatct ctatacaact cttgagattg tcaatgagat gtgggaacga
    25681 ggtttcaagt ttggtaaatt agatctctac cgtagtcagg cgacagagtt cctcatcgac
    25741 ggggataccc ttatcccacc atttgtagca atggatggtc tgggagagaa cgttgccaag
    25801 caactggtgc gggcgcgtga agagggagaa ttcctctcta aaacagaact acgcaagcgt
    25861 ggtggactct catcaacctt ggttgaaaag atggatgaga tgggtattct tggaaatatg
    25921 ccagaggata accagttgag tttgtttgat gagttgtttt aaaaaattgc ttaataatct
    25981 attaaaagag gctaacgtat atccaataga tttacattag ctttcttttt tgttaaaata
    26041 gtctatggaa agagggtgag agtatgtcaa agatgagtat aagcatccgt ctggatagtg
    26101 aggttaagga gcaggcccaa caggtgttta gtaatctggg aatggatatg acaacagcta
    26161 ttaatatttt ccttcgtcag gcaattcaat atcagggatt accttttgat gttagactag
    26221 acgaaaatcg gaagttgctc caagcgttaa cggatttaga ccaaaatcgt aatatgagcc
    26281 agtcttttga atcagtctca gatttgatgg aggacttacg tgcttaagat tcgttatcat
    26341 aaacagttta aaaaagattt taagttggct atgaagcgtg gtttgaaggc agaattatta
    26401 gaagaagttt tgaattttct ggttcaagaa aaagaacatc ctgccagata tcgtgatcat
    26461 tcattgacgg catccaagca ttttcaagga gttcgtgaat gccataccca gccagattgg
    26521 cttttggttt ataaagtaga caagtcggaa ttgattttaa atttgctgag gacaggcagt
    26581 cacagtgatt tattttaatc tattttaagg gggttctcat gaaactaaga atatttgcgg
    26641 aagataagcc ggctaagaag gtatttgaat atcaattaga acttgctgat cgtacaattc
    26701 ttctatcgac agcactcttg tcaggtgcta ttgctttagc aggaatcttt tctgctttga
    26761 aagaaaaata aaaatagaaa agagaaaaca gaatggtttt accaaatttt aaagaaaatc
    26821 tagaaaaata tgcgaaattg ttggttgcga acggaattaa cgtgcaacct ggtcacactt
    26881 tggctctctc tattgatgtg gagcaacgtg aattggcaca tctaatcgtg aaagaagctt
    26941 atgccttggg tgcgcatgag gtcatcgttc agtggacaga tgatgtgatt aaccgtgaga
    27001 aattcctcca tgccccgatg gagcgtttgg acaatgtgcc agaatacaag attgctgaga
    27061 tgaactatct tttggagaac aaggctagcc gtcttggggt tcgttcatct gatccaggtg
    27121 ccttgaacgg agtggacgct gacaagcttt cagcttctgc taaagctatg ggacttgcca
    27181 tgaagcctat gcgtatcgca actcaatcta acaaggttag ctggactgta gcagccgctg
    27241 ctggacttga gtgggctaag aaagtcttcc caaatgctgc gagcgacgaa gaagcagttg
    27301 atttcctttg ggatcaaatc ttcaaaactt gtcgtgtcta cgaagcagat cctgttaagg
    27361 cttgggagga acatgcagcc attctcaaga gcaaggccga tatgcttaat aaggagcaat
    27421 tttcagccct tcactacaca gcgccaggaa cagatttaac acttggtttg ccaaagaacc
    27481 acgtttggga atcagctggt gctgtcaatg cacagggcga agaattcttg ccaaatatgc
    27541 cgacagaaga ggtcttcaca gcgcctgact tccgtcgtgc agatggttat gtcacttcta
    27601 caaaaccgct tagctacaac ggaaatatca ttgaaggcat taaggtgacc tttaaggatg
    27661 gacaaatcgt agatatcact gctgagaagg gtgatcaggt tatgaaagac cttgtctttg
    27721 aaaatgcggg tgcgcgtgcc ttgggtgaat gtgccttggt accagatcca agtccaattt
    27781 ctcagtcagg cattaccttt tttaacaccc ttttcgatga aaatgcgtca aaccacttgg
    27841 ctatcggtgc agcctatgcg actagcgttg ttgatggagc ggagatgagc gaagaggagc
    27901 ttgaagctgc agggcttaac cgttcagatg ttcacgtaga ctttatgatt ggttctaacc
    27961 aaatggatat cgatggtatt cgtgaggatg gaacgcgggt acctcttttc cgtaatggga
    28021 attgggcaaa ttaaggagat aatatgttag gaagtatgtt cgttggtctc ctagtgggat
    28081 ttttagcagg tgctatgacc aatcgtggag agcgaatggg atgttttgga aaaatgtttc
    28141 tcggttggat cggagccttt ctaggtcact tgctctttgg aacttggggg ccagttttat
    28201 caggaacagc tattatccca gcgattttag gagccatgat tgttttagct attttttgga
    28261 gacgaggaag ttaatttcct aaatctgata ctcaatgaaa atcaaagagc aaactaggaa
    28321 actagccgca ggttgctcaa agcactgctt tgaggttgca gatagaactg acgaagtcag
    28381 ctaaaaacac tgttttgagg ttgcagatag aactgacgaa gtcagtaaca tatatacggc
    28441 aaggcgacgt tgacgcggtt tgaagagatt tttgaagagt atgaaacgaa aaggaggttg
    28501 gtcattgtac tagcctcctt ttgatatgat ataatagttc tatgagatta gataaatttt
    28561 tagttgcctg tgcggtggga agtcggactg aggtcaaaaa cttgctcaag gctgggcgcg
    28621 tgactgtaaa tggtaaaaaa gaaaaatcag ctaaattgca gattgatgaa aaaatagatg
    28681 agattcgctt tgatgggcaa gtgttggagt atgaagagtt tgtctactac atgatgaaca
    28741 agcccaaagg agttatctca gcgactgagg atcccaagca cagaaccgtt ctggacttgt
    28801 tggatgactt ggcgcggagt aaggaagttt ttccagtagg acgcttggat attgacacgc
    28861 atggtctttt gctcttgacc aataatggtc agctggctca tgttcttctt tcgcccaagc
    28921 gtcatgtgga caagacttat caggctcagg tcaagggaat tatgacccaa gaagatgtgg
    28981 agacatttat caagggcatt ccgctcaaag actttacctg tcagcccgct agactggaga
    29041 ttctttccac agatgcagaa aagaatcaga gccaaatccg tgtgaccatt gcagaaggga
    29101 agtttcatca gatcaagcgt atggtgggct actgtggcaa ggaagtggtg gacttgcaac
    29161 gattgactat gggaacttta gtattagatg agaacctgga acgaggggaa tggcgtcgct
    29221 tgaccaagga agaattagaa attctccgcg ctaatattat ttaatttagt ttaatactca
    29281 atgaaaatca aagagcaaac taggaaacta gccgcaggct gtacttgagt acggcaaggc
    29341 gacgttgacg tggtttgaag agattttcga agagtataaa ttcgaaaaag gtgagggaga
    29401 atgtccttac cttttatgtt ttttagttgc ttcctttgtg aaaagagtta taatagactg
    29461 tagaataaaa ggaggaatct atgaacgcga ttcaagaatc atttactgat aaactatttg
    29521 ccaactatga agcaaatgta aaataccaag cgattgaaaa tgctgccagc cacaacggaa
    29581 tttttgcagc tctggaacgt cgccaaagcc atgtagacaa cacacctgtt ttctcattgg
    29641 atttaaccaa ggacaaggtc actaaccaga aagcgtctgg tcgttgctgg atgtttgcgg
    29701 ctctcaacac cttccgccac aaactcatct cgcaatacaa attggagaac tttgagttgt
    29761 cacaagccca cactttcttc tgggataagt atgagaaatc aaactggttc ttggagcaag
    29821 tcattgcgac ttcagaccaa gaattgacta gccgcaaggt tagcttctta ctccaaacac
    29881 ctcaacaaga tggtggtcaa tgggatatgg tcgtttccct ctttgaaaaa tacggtgtcg
    29941 tgcctaagtc agtttatcct gagtctgttt catctagcag cagtcgtgag ctaaatgcga
    30001 tccttaataa attgcttcgt caagatgctc aaatcttgcg tgatttgctt gtttctggtg
    30061 cagatcaagt gactgttcaa gctaagaaag aagacctctt gcaagaaatc tttaactttc
    30121 ttgctatgtc attaggactt ccaccacgca agtttgactt tgcttatcgc gataaagata
    30181 acaactacaa aagtgaaaaa ggaatcacac cacaagagtt ctacaagaaa tatgtcaatc
    30241 ttcctttaga agactacgtt tctgttatca atgctccaac tgctgataaa ccttacggaa
    30301 aatcttacac agttgagatg ttggggaatg tggttggtag ccgtgcagtt cgttacatca
    30361 acgttccaat ggagcgcttg aaagaattgg cgattgccca aatgcaagca ggtgagactg
    30421 tttggtttgg ttctgatgtc ggccagctca gtaaccgtaa ggctggaatc cttgcgacag
    30481 atgtttatga ctttgaatca agcatggaca ttaaacttac tcaagacaag gctggacgtt
    30541 tggactatag cgaaagcttg atgacccacg ccatggtctt gacaggtgtt gacttggacg
    30601 aaaatggtaa atcaaccaag tggaaggttg aaaactcatg gggagacaag gtcggtacag
    30661 atggttactt tgttgcctca gacgcttgga tggacgaata cacataccaa atcgttgttc
    30721 gtaaggaatt gctgacagca gaagaacaag ctgcctatgg agcagaacca attgtacttg
    30781 caccatggga tccaatggga gccttggcta aataaaagca tagaaaaaag gaatcagatt
    30841 ttagaacctg gttccttttt agttgcttga ttacatgatg tgaagaacat gtgccacaat
    30901 acccactgcg aagagggcaa ggataatagt gattggagat acttttttct taagtaagta
    30961 catgcaaagt aaagtaagga gtagtcctga taatccagga atcaacatat ccaagttttg
    31021 ttggaaagta gtaacttttt caggagtttg agacaatcct tgtcctactt gtgcgaatgc
    31081 ttcttggata cctttagacc cttctggcaa tttatcccaa tggatataag ccttttcatc
    31141 tagttgaact ttagaaacat cgaaagcaaa tttaatattt acccagcgtt gaacaaggac
    31201 agcaagaatg aacatcccaa ggatagaagc tcctttagtg atatcttgaa ggataccacc
    31261 agacatatct ttagtgattt ctgatccagc cttgtatcca atctcttgaa cataccacaa
    31321 gaatgacata cgaatcaagt tccatgcaac aaagaagagg agtggcccca agatattgcc
    31381 agtaagggca agtgaagcac cgagagatcc aaggattggg cgtactgtaa accagaatac
    31441 tgggtcaccg ataccagcaa gaggtcccat cataccgatt ttaacccctt ggatagcagc
    31501 gtcatcgatt tccacaccgt tagcacgttc ttcttcaagc gcaagagtaa cccccatgac
    31561 tggagcagct acgtatggat gagtgttgaa gaactcaagg tgacgctcaa gagcagcgat
    31621 ttgatcttct tttttagtat agagtttttt gatagctgga atgagtgtat aagcccagcc
    31681 caagttttgc atccgttcaa agttccaaga cccttgtaag aaggttgaac gccaccaaac
    31741 ttttttacga tctgatttag ttaattgaag tttttcagtc atgatgtttt cagtcctttc
    31801 ttatcttagt agtcttctag gatatcgccg attgggtcgt tagaagttgc ggctcctccg
    31861 ccaccatttc caccagtttt agaaaggtga aggtagataa gagcgatagc aacaccgata
    31921 gcaccgaatc cgattagagt aatatctgac acagcagcga gaacgaaacc aagagcgaag
    31981 aatggccata cttcacgagt tgccatcatg ttgataacca tggcgtaacc aacggcaacg
    32041 accataccac caccgatagc cataccatct ttgagccagt ctggcatggc actaaggata
    32101 ctttgtacag tttcagttgg taccataagg agaagagctg caggaagcgc gatacgaagt
    32161 ccttggaaga gtagcgcaat gaaatgcgca cgctccacag cgccgaagtc acctttttta
    32221 gcggcagcat ctgcagtatg aaccaaacca actgaaattg tacgaacaat cattgtcaag
    32281 aaaagtccag ctacggcaag agggatagca accgcttggg caacaccgat accagtcttg
    32341 gtaaagtcac caccaagaac catgataatg gcagcagcga cagaagcaag tgcagcatca
    32401 ggagcgatag cagcaccgat atttgaccaa ccaagggcaa tcatttgaag cgatccaccg
    32461 aggataatcc ctgcttccaa gtgacctgtt acaagcccaa taagggtaca ggctacaagt
    32521 ggttggtgaa attggaactg gtcgaggatg ccttcaagac ctgcaaagaa ggctacaacg
    32581 actactaaaa ccatagaaat aatagacatg tttaaaatcc tttcataaat aatggcttat
    32641 ttgacattgg ctttgttaat caagtcaaac aaatcttttt tagaatcatt tggtacttta
    32701 cggacatcaa attcaacacc caagtcacgc attttttcaa atgtagcaac atcttctttg
    32761 tccatagaca aaacggtatt gaccaatgtt ttacctgttg agtgagccat agaaccaacg
    32821 ttaagagtct tgattggcac gccgccttcg atggcacgaa gggcatcttg aggtgtttca
    32881 aacaagataa gggcatgtgt ttctccaaaa cgtgggtctt ttgaaatctc aatcagtttt
    32941 tgaattggaa ccacgttagc cttgacatta cctggagctg cttgtttaat caattcttta
    33001 cgaaggtcgt ctttagccac gttatctgaa gcaacgatga tacgatttgc ttttgaatct
    33061 ggagtccaag cagttgcaac ctgaccgtga agtagacgtg tgtcaagacg ggcaagattg
    33121 attttcaatt taccgtctcc gataacagtt ccttctggga tagcagtttg ggcaactgga
    33181 gcagctgcag cgcttgcaac ttcttcaact ggatttagct cttctggaag agctttgatg
    33241 ccatctttgg cttctttaat gatattagca gcgacttttt ctacacctgc agcagcgtcc
    33301 atgaggcgct ctgtgtaggc ttgaatcaac atcggtaagt taagtcctgt gatgatggca
    33361 aacttacgct caggattttc tcccatcacg cgactagctt ggttaaatgg agaaccactc
    33421 caaaggtcag ccaaaactag aacctcatct tctgcgtcaa atgcagcaac agcgttatta
    33481 aacttagtgt atagatcatc aggaccttca tttggcataa aggtcacaac ttgaaccttt
    33541 tcttgttcac caaagatcat agatcctgac tgatgaatac ccgcagcaaa ttcgccgtgg
    33601 ctcgcaataa tgattccgat actcattatt gtcattcctc cttttttgtt ttagttttca
    33661 tttaagaaaa ctttaagact gtttaagtat aaaccgtttt cataaaaaaa gcaactattt
    33721 atcataaaaa attaaaaaat ttttattttt gtatgttgat atgttgagtt tttgaggagt
    33781 aatcttgaat tcttatttaa aatttaatat aaaaaagttg gaagaagctt ccaactttta
    33841 aaataggttt ctattagatt agtgggtgaa gtcgagtacc atacgtcctt ggatttggcc
    33901 tttttccatt tcgtcgaaaa tggcaacagc atcttctact ggacgttttt gaacaactgg
    33961 gactaccaga ccttctgcac caaattggaa ggcttcttct aagtctttac gagttccgac
    34021 aagagaaccg atgacttgga ttccatcgag gactgtttta acgatgctga gttccatcat
    34081 ttcagaagga agaccaacag cgacgacgcg accaccagca cgaatggagt caacagcctg
    34141 gttgaaggca actttagaca cagcagttac gacagctgaa tgagctcctc catcagtttt
    34201 ttctttaatg agtccagcta catcttcaac ttcgaggccg ttaatcacaa tgtcagcgcc
    34261 tacttctttt gcaagggcaa gtttgtcatt gttgatatcg actgcgataa catgagcatt
    34321 gaatactttt ttagcgtatt gaacagcgag gttaccaagt ccaccagcac cgtaaagaac
    34381 aacccattgg cctggttcaa cttttgcttc tttgatagct ttataggttg ttactccagc
    34441 acatgtgata gaagaagctt gggctggatc aagtccgtca ggaactttga cagcatagtc
    34501 agcagttacg atacattgtt cagccatacc accgtctact gagtagccag catttttcac
    34561 tgtacggcaa agggtttcgc gaccagttgt acagtattcg caagtgccac atccttcaaa
    34621 gaaccaagca acgctgacgc ggtcaccgac tttaaggctt ttcacatctg gagcaatctc
    34681 tttaacgata ccgatacctt cgtgcccaag aacacgtcct gggacttgac caaagtcacc
    34741 atgagcaacg tggaggtcgg tgtggcaaac accacagtat tcaacttcta caagtgcttc
    34801 cccagtttca agtggacgga gtactttttc ttcaatagca acaccagtgc tttctggatt
    34861 tacaacaaca gctttcatag ctatcctcct tgatattgac cgagaacagg gacaacggga
    34921 ctggattgat tttttgtcaa cagagtcgag tgtgacgagc tctcttgtat ttatatgtga
    34981 agtatatcac aaaagaaagc cttttccaag gttttggaga caaaaagtag aacaatcgat
    35041 taactggttg atgagactgt gaaaagagca caaagaccag cttgcaagct ggtcatactc
    35101 ttcgaaaatc tcttcaaacc acgtcagctt catctacaac ctcaaagcag tgctttgagc
    35161 aacctacggc tagcttccta gtttgctctt tgattctcat tgagtatcag tataggttat
    35221 aagaataagt cttgtagggt tttggcaacc ccatcttggt cgttggtaag ggaaatttgc
    35281 tcatctgcat aagggagtag ctctggattg gcatttttca tggcataacc cttcccagca
    35341 aaagcgagca tttcggtatc attgtgttca tctccaaagg caatcaaatc ttttttgtca
    35401 cgattcatta tcttgagcaa gtagtccaaa gcaaaggcct tgttgacacc ttttggggta
    35461 cattcaagga tattgagcgg acctccccag gtattgatag aaagttgatg ctggtagaag
    35521 gcgttcatgt cttttgccaa ggcatatttg tcactggctc tggtctgcaa gaggatacag
    35581 ttagggtcct tggtcaccaa ttcaggctgg aattgatctt caggctggaa agcttctaca
    35641 ccaaatagtt tgggattggc aatttcttca ttgggatttg taatgtagaa ttttttacga
    35701 tattctccag cgataaaatc ggcttgaatg tcctctgaac gttgaaccat atctagcaga
    35761 tattttttgt ctacagtcaa acacttttca aaatcccaaa cttggtctgg taaatgagta
    35821 agggatccgt tgaagttaat cataggagtg tctaagccca gttcacggta aaaatctttt
    35881 gacatacggt aagggcgacc tgtcgtaata ataacctgat ggcctttttc agcaactttt
    35941 ttgatggttc ttttggtaaa gtcagaaatt tgactgtctg agttgagcag ggttccatcc
    36001 aggtcaactg caataatttt tttcgtcata tggacctttc tagtgtgttt tcagataaga
    36061 tgtcttctat tataacagaa agcaggcaga aaagcagatt ccaaacaaaa aatgaaattg
    36121 gattaatttc ttaaacaaat caaacaaaga cattgaaaaa gtgaatgata aatgatataa
    36181 ttctattatt gttcgtaaaa attaaaagga gattgatgat ggacaaatta tttaaactaa
    36241 aagagaacgg tacagacgtt cgtacagagg ttctcgctgg tttaacaact ttctttgcaa
    36301 tgagctatat tctctttgta aacccacaaa tactttcaca aacaggaatg cctgctcagg
    36361 gcgtcttcct agcgacgatt attggtgcag tagcgggtac cttgatgatg gctttttatg
    36421 ctaacttacc ttatgcccaa gcgccaggta tgggactcaa tgccttcttt acctttacag
    36481 ttgtattcgg gcttggttat tcttggcaag aagccctagc tatggtcttc atctgtggga
    36541 ttatttcatt gattattacc ttgacaaatg ttcgtaaaat gatcattgaa tcgattccca
    36601 atgctcttcg ctcagctatt tcagctggta tcggtgtctt ccttgcctat gtagggatta
    36661 agaatgctgg acttttgaaa ttcacgattg atccaggcaa ctatactgtt gtaggagaag
    36721 gggctgacaa agctcaagca acgattgcag caaactcttc agcagttcca ggattggtca
    36781 gctttaataa tccagctgtt ttagtggctc ttgcaggact tgccattact atcttctttg
    36841 tcatcaaagg gattaaaggg ggaattattc tctctatctt gacaacaact gttcttgcta
    36901 ttgcagttgg tttggttgat ttgtctagta tcgattttgc taataaccat gttggtgcag
    36961 cttttgaaga tttgaagaca atctttggtg cagctcttgg ttcagaaggt ttgggagctt
    37021 tggtttcaga tacagctcgc ttgcctgaaa ctctgatggc cattcttgcc ttctcattga
    37081 cagatatttt tgacacaatt ggtaccttga tcggtacagg tgaaaaagtt ggtattgtag
    37141 cgacaaatgg tgaaaatcac caatcagcca aattggataa ggctctttac tctgatttga
    37201 ttggaacgac agtcggtgcc attgcaggta cttcaaacgt aacgacttat gttgagtctg
    37261 ctgctggtat cggtgcaggt ggacgtactg gtttgacagc cttggttgta gctatctgtt
    37321 ttgcgatttc aagcttcttt agcccacttc tagcgatcgt accaacagcg gctacagctc
    37381 caatcttgat tatcgttggg attatgatgc ttggtagctt gaaaaatatc cattgggatg
    37441 atatgtctga agcagttcct gccttcttca catctatctt tatgggattc agctactcta
    37501 tcactcaagg gattgcagtt ggtttcttga cttacacttt gactaagctt gtcaaaggtc
    37561 aagttaaaga tgttcatgcc atgatttgga ttttggatgc cttgtttatc cttaactaca
    37621 tcagcatggc cttataatag aatgacccag ggggattttc cccctttttt aatacaaagg
    37681 agataggtga tgaaagagaa aaatatgtgg aaagaattgt tgaatcgtgc aggctggatt
    37741 ttggtctttt tacttgccgt ccttttatat caggttcccc tagtggttac ctctattttg
    37801 actttaaaag aagtagccct gctacagtca gggctgatag ttgctggcct ttcaattgtg
    37861 gttctggctc tatttattat gggagctcgt aaaaccaagt tagctagttt taatttttct
    37921 ttttttagag ctaaagattt ggcacgtttg ggcttgagtt atttagttat tgtcgggtca
    37981 aatatacttg gttctatctt gttgcaactg tcaaatgaga cgacaacagc taaccagtct
    38041 cagattaacg atatggttca gaatagttct ctgatttcta gcttcttctt gctagccttg
    38101 cttgctccaa tttgtgagga aatcttgtgc cgtgggcttg ttcctaaaaa gattttccga
    38161 ggcaaggaga acttgggatt tgtagtcggt acgattgtgt ttgctttatt gcatcaacca
    38221 agtaatttac cttctttatt gatttatgga ggtatgtcga cagttctatc ttggacggcc
    38281 tacaagaccc aacgtttgga aatgtcgatc ttgcttcaca tgattgttaa tgggattgct
    38341 ttctgtttgt tggctcttgt ggtgattatg agtcggacat taggaatttc tgtgtaaaag
    38401 tttttatgta ggaaccgacc tctttctact agggaaagat gaatgcaatc gtgtccatct
    38461 ttttcttttt atggtaaaat agaaaaataa tatgatgaaa atccttgagg gagtgaccga
    38521 tatgtcaagt aaagccaatc atgcaaagac agttatttgc ggaattatca atgtaacccc
    38581 agactccttt tcggacggtg gtaaattttt tgctcttgag caggcactcc agcaggctcg
    38641 taaattgata gcagaaggag ccagtatgct cgatatcggc ggagaatcga ctcggccggg
    38701 cagtagctat gttgagatag aagaggaaat ccagcgtgtt gttccagtga tcaaagcgat
    38761 tcgcaaggaa agtgatgtcc tcatctctat tgatacttgg aagagtcaag tagcagaggc
    38821 tgctttggct gctggtgccg atctagtcaa tgatatcact ggtcttatgg gtgatgagaa
    38881 aatggctcat gtggtagctg aagcgagagc gcaagtggtc atcatgttta atccagttat
    38941 ggcgcgacct cagcacccta gctcgctcat cttccctcat tttggttttg gtcaagcttt
    39001 tacagaggaa gagttagctg actttgaaac attgccaatc gaagaattga tggaggcttt
    39061 ctttgaacga gcactagcga gagcggcaga agctggtatt gcaccagaaa atatcctgtt
    39121 ggatccagga attggctttg gtctgaccaa gaaagaaaat ctgcttcttt tacgggacct
    39181 ggataaacta catcagaagg gctatccaat ctttctcgga gtgtcgcgca agcgatttgt
    39241 catcaatatc ctagaggaga atggttttga agtcaatcct gagacagagc ttggtttccg
    39301 aaatcgggac acggcttcgg ctcatgtaac tagtatcgct gcgagacagg gtgtagaagt
    39361 ggtgcgcgtg catgacgtag ctagtcacag gatggcagtt gaaattgcct ctgccattcg
    39421 tctggctgat gaagcggaaa atttagattt aaaacaatat aaataagatg aaagaaattg
    39481 aaaacaatca gtggattgct aactaccgga cggatcaacc gcattttgga ttggaacgaa
    39541 tggtggaact gttagctttg cgtggcaatc cccatctcaa actcaaggtc ctccatatcg
    39601 gagggactaa cggcaagggc tcgactattg cttttttgaa aaagatgcta gaaaagctag
    39661 ggctgagagt tggcgtgttt agctcgccct atctcattca ttacacagac cagattagca
    39721 tcaatgggga atcgatctca gaagcgaggc tagaagctct catggcagac tatcagtctt
    39781 tgctggaggg agaagcggtc gccaatttac agggcacaac cgagtttgag attatcacag
    39841 ccctggccta tgactacttt gcctcagagc aagtagatgt ggccatcatg gaagttggca
    39901 tgggtggact tttggatagt accaatgtct gtcagcccat tttgacagga attacaacta
    39961 ttggcttgga tcatgtggcc ctacttggtg acaccttgga ggccatagca gagcagaagg
    40021 caggtattat caaacaaggg atgcccttgg taacagggcg tattgctcca gaagccttga
    40081 ctgtgattga ccgcattgcg gaagggaaag atgcgccgag acttgcctac gggacagatt
    40141 atcaggttcg tcatcaagaa agtgtggtga caggggaagt ctttgactat acaagtgctg
    40201 tcagacaagg tcgcttccag actagcctgc ttggtttgta ccaaatagag aatgctggga
    40261 tggccatagc tttacttgat actttttgtc aagaagatgg tcgagagcta gcaagcaatg
    40321 actttcttgg tcaagccttg gaagaaacaa gttggccagg gcgtttggaa atcgtgtcaa
    40381 gagatccctt gatgattttg gatggagccc ataatcccca tgctatcaag gccttgttgg
    40441 taaccttgca agaacgtttt gcggattatc ataaggaaat cctcttcact tgtatcaaaa
    40501 ccaaagcctt ggaggatatg ttggacttgc tgggagccat gccagatacc gagcttactc
    40561 taacacattt tgcggatagt cgggcgacgg atgaaagcgt gctgaaagag gcagctaagt
    40621 ctagaaatct cagctaccaa gattggcatg attttctaga gcagaatgtg acagataaaa
    40681 aagaagagaa acaaacagtt aggattgtca caggttcctt gtatttcttg agccaagtga
    40741 gggcctatct gatggagagg aagaacgaga atggatacac aaaagattga agcagctgta
    40801 aaaatgatta tcgaggctgt aggagagaac gctaatcgcg agggcttgca ggaaacacct
    40861 gctcgtgtag cccgtatgta tcaagagatt ttttcaggtc ttggtcaaac agcagaggaa
    40921 catttgtcaa aatcctttga aattattgac gataatatgg tggtagaaaa ggatatcttt
    40981 ttccatacca tgtgtgaaca ccacttcttg ccattttatg gtagagcgca cattgcctac
    41041 attccagatg gtcgtgtggc aggcttgtct aagctagccc gtacggttga agtttattcg
    41101 aaaaaaccac aaattcaaga acgtttgaat atcgaagtgg ccgatgcctt gatggactat
    41161 ctaggtgcta aaggagcctt tgttgtcatt gaggcggaac atatgtgtat gagtatgcgt
    41221 ggtgttagaa aaccaggcac tgcaaccttg acgacagtag ctcgtggtct atttgaaaca
    41281 gataaggacc tccgcgacca agcttatcgt ttaatggggc tataaaaaga atccgcttca
    41341 agcggatttt tctagaaagg aatcattatg gatcaactgc agattaagga tttggaaatg
    41401 tttgcctatc atggtctttt tcctagtgag aaagaattgg ggcagaaatt tgtcgtttca
    41461 gccatcctat cctatgatat gaccaaggca gctacagact tggatttaac agcctctgtc
    41521 cattacggag aattgtgtca gcagtggacg acttggtttc aggaaacgag tgaagatttg
    41581 attgaaacgg tagcctataa actggtggaa cgtacctttg agtcttatcc tcttgtccaa
    41641 gaaatgaagt tggaactgaa aaaaccttgg gcaccggtgc atttgtcact agatacttgc
    41701 tcggtaacca tccatcgccg caagcaacga gcctttatcg ccctaggaag caatatggga
    41761 gataaacaag caaacttgaa acaagccatt gagaaaatgc gaaatcgagg tatccatatt
    41821 ctcaaagagt ccagtgtctt agcgacggag ccttggggtg gagtggagca ggatagcttt
    41881 gccaatcaag tggttgaggt ggaaacctgg ctaccagcac aagacttgtt agaaaccttg
    41941 ttagccattg agtcagagct gggacgggtg agagaagtgc attggggacc tcgtttgatt
    42001 gatttggact tgctctttgt ggaggaccag atcctttata cagacgacct catattgcct
    42061 catccttaca tagcggaacg cctttttgtc cttgagtcct tacaggaaat tgcgcctcat
    42121 tttatccatc cgatattaaa acaaccgatc cgcaacttgt atgatgcttt gaaaaaatag
    42181 aaaaactcta gttttcagtt acttgcaact gaaggctaga gtttttaaaa taggtcattt
    42241 tcttctggga ggaggatagt ttctctaccg tccatgtcta aaaccagtac tcttggggga
    42301 taacgagggt cgaaaggatg gttaaagtca aaatcaatgg ctgtagggag gtgttgactt
    42361 gaaaagtgga aggtaatctt tccttggtta ttaagcaatt gaaactcgag ttcttcttcc
    42421 aattcaaaga cattttttaa gaaatgatcg atgatatacc aaaaagagtc aatgatgtca
    42481 tcgggcaagc tggtaacaat gccaaaacta gcagaccgca tgtgggtatt ggtaaaagcc
    42541 atatctctgt cccctttctt ttcccttatc atacagcaaa taggattaaa aatcaagaaa
    42601 aggtgatttt ttgaaaagga ttttagttac agggagaaat agggaaaaat tcccaaaaat
    42661 ctaccgaagt taataggtaa attcccaaat taacttgatt atataacttt cagttatttt
    42721 gagaagttac cgaaaaatat tttttatatc tattgacttt taggggtgaa atttggtatg
    42781 atagtaggcg gtattgttta ccccatttga aaggccccgg aaccttccaa atacttttcg
    42841 atgggaagga acacccatca ccgtaaacaa aaatcgaact atatatagga gaaatcatga
    42901 acaaaacaac atttatggct aaaccaggcc aagttgaacg taaatggtac gtagttgacg
    42961 caactgatgt accacttgga cgtctttctg cagtagttgc tagcgtactt cgcggaaaaa
    43021 acaaaccaac atttacacca cacactgata caggtgactt cgtgattgtt atcaatgctg
    43081 aaaaagttaa attgactggt aaaaaagcaa ctgataaaat ctactacact cactcaaacc
    43141 acccaggtgg attgaaacaa atctctgcag gtgaacttcg ttctaaaaat gcagtacgtt
    43201 tgattgagaa atcagttaaa ggtatgcttc cacacaatac acttggacgc gctcaaggta
    43261 tgaagttgaa agtatttgtt ggagctgagc acactcacgc tgcacaacaa ccagaagttc
    43321 ttgacatttc aggacttatc taaggaaagg aacaataaag tatgtcacaa gcacaatatg
    43381 caggtactgg acgtcgtaaa aacgctgttg cacgcgttcg ccttgttcca ggaactggta
    43441 aaatcactgt taacaaaaaa gatgttgaag agtacatccc acacgctgac cttcgtcttg
    43501 tcatcaacca accattcgca gttacttcaa ctgtaggttc atacgacgtt ttcgttaacg
    43561 ttataggtgg tggatacgct ggtcaatcag gagctatccg tcacggtatc gctcgtgccc
    43621 ttcttcaagt agacccagac ttccgcgatt cattgaaacg cgcaggactt cttacacgtg
    43681 actcacgtaa agttgaacgt aagaaaccag gtcttaagaa agctcgtaaa gcatcacaat
    43741 ttagtaaacg ttaattcgaa agaattacta tacttataca gagcaccttt cggggtgttc
    43801 ttttttatac tttcttacta aattggtgca attgacacag ttgttgcgac tttagtcgct
    43861 tacaaatgtg gctgcaacct gacaaggtca gttgcctcaa aacgttaatc aatacgatta
    43921 tatcaacgtt tcaaagcact caagagttta cctcatgggt gcttttttta tgttttttga
    43981 aaaagttcac ctcaaagttt accttatttt caccttattg ttttagagac tgtaaggcaa
    44041 attcaccgac ggccataggg actacattag aagtattgac ataaatctgt gttgtacctg
    44101 tgtcgctatg tattagagct tcagaaatgg cttctaagct cattcctgct tgtttagcga
    44161 gcgttgctcc ggtatgacgt agtttgtgtg gcgtagcgtg tgtaagctct gggtgtcgtt
    44221 ttctgatagt tttcatctta ttattgagat agtcagaatg taaaggttta ttgatattgc
    44281 ctttggtatc tatgtaagta aagatgaatt gttctggatt actgatgata ccaaactttg
    44341 ccagttcata tttttgttgt tttttccatg aagtcagaag ttgaagtaag tcattagaaa
    44401 tagagaaaat gggaaatgtt tccacaataa aacgcatatt atcagatggt taatgcgttt
    44461 tatatttggg ttttaggctt ataaaatagg ataagcgtac tgaaaactta gatatgacaa
    44521 acaaaataaa atttttaaaa gctacagaga aacatggtat aatgtatcta aaggaggtag
    44581 catatgtcct tagatataga taaagaaaag atgacaatca tgggaatagc ttttgaaaac
    44641 cgatccgttt ttaagagtgt ttggtatgct ttaagtacaa atatgattga aggatggcga
    44701 cctacggtta gtgatgttga aaaattacga gatgaagctc ttgctctggg gatgacttaa
    44761 tgaagcgcaa ctgttatgag tcttatgact atgttgatcc ggataattta tataccgatc
    44821 cgggttcttc agttctaaga aataagcagg aaggaaaaaa gcacgcgagc ttgaatatcg
    44881 tatgattgct agtaagagtt tgaaattatt tatcaatcct atcttagtta atagtttaaa
    44941 agtagtttgt ttcacaactg cataagctta gaaaagttga aaagtgataa ctctttaata
    45001 aactcttggt ttgttaaaag atattttgtc cactacattt tttcaattga ctattatttg
    45061 tcatagatat aacagataga acattgcatt cagaataatg aaaaacgcat caaaaatggt
    45121 gcgttctgtt tttatgctac cataaaagga ggaaaacaaa ttgaaaattt ttaagggaga
    45181 gttttatcga atctctgtat taacagacaa gctagtaagg ttagaatact ctcaaactgg
    45241 aagttttgag gatagaacga cacaacttat ctataataga gattttggcc aagtttcgtt
    45301 agattatatc gagacatcaa acgtactaga tattatgacg gactattttc atctgcactt
    45361 taataaagga gaatttaacg ccgaaaattt atttatagaa ttaaaaggaa attttgccgt
    45421 atatggtagt cgctggtatt ttggtgaatc tattgaaacg ttaaaaggaa cagctcggac
    45481 tctggataag gcagatggag caatctcgtt agaagatgga attattagcc gaaatggtat
    45541 agccttattg gatgattctc aaggatttat ttgggatgaa caatctggtt atattgagag
    45601 agaaaatcaa attgacctgt atttctttgc ctatgggcat gattatagag gagcaatcag
    45661 agacttttac catttgactg gttcaacacc cttgttgcca agatatgctt taggcaattg
    45721 gtggagtaga tattggcctt atacgtcgga tgaatacttg gatttaatag acagatttgc
    45781 aacagagaaa attccattat ctatcggtgt gttagatatg gattggcata taactgacat
    45841 tccagctcgt tttggaagtg gctggacagg atatagttgg aatagaaact taataccaaa
    45901 tccagaacag ttattgcaac aacttcatga tagaaagtta aaactctcct taaatgtcca
    45961 tcctgctgat gggatacggg cttatgaaga agcttatcct caaatcgcaa aacggttggg
    46021 gttaaatgta gaactagaag aacctgctat ttttgatttt tttaatccct cttttaggga
    46081 agcctacttt aaagatgttc attatgagct agaaaagcag ggagtagatt tttggtggat
    46141 tgactggcaa caggggacac aaggcatgct agatccactt tggcttttaa accattatca
    46201 ctatcaggat agttgtaaaa atgcagaagg tggtttgatt ttatcaagat atgcaggtcc
    46261 tggtagtcac cgctaccctg ttggtttttc aggggatact attatcagtt ggaattcctt
    46321 aagatttcaa ccctatttta cagcgacagc atctaatatc ggttatagtt ggtggagtca
    46381 tgatatcggt ggacatatgt tgggggatta tgacgaagag ctacaaacta gatggctaca
    46441 gtttggtgtt tttagtccga ttactcgatt acatagttct agaagtcctt ttaatagtaa
    46501 agaaccttgg tttttttcag aaacaacatc taagattatg aagaaatacc ttcgtttgag
    46561 acatcagatg attccttatc tatataccat gaatgtaaag acacatgagg aaggtgcccc
    46621 attaatcagt ccaatctatt atttctatcc agagaatgat gagagctata atgttccaaa
    46681 ccaatacttt tttggaacag aactgatggt ggctcccatt gtagaaaaga tggatttgac
    46741 attccaatct gcaaaagtag atgtatggtt ccctgaaggt gaatggtatg acttcttttc
    46801 agagaaaaaa tacacaggtg gtgtgaagtt aagtgtttat agggacatct cgactacgcc
    46861 tgtgtttgca aaaagtggtg caatcattcc cttggttggt tctgagatag gtatgggtgt
    46921 tgatttacct gaggttgtag attggtatgt attcccaggg aaacaacatt cttttgaaat
    46981 gcttgaagat caaaatggtc aaagatataa aacaagatta tcaatcgatt gggaaatggg
    47041 aatggtagag ttagcattac aaggagattc tagtatcgtt ccaagcaata gaaaacatag
    47101 aattcatttt aaaggaacga atgtgtctat aattgaattg ccaaataaga atgatacagc
    47161 taaatttgaa tggaaagata ataaaaggac atctttaaat gacgaagttt ttagactact
    47221 aaagacagct tctcttccat atgaattaaa agatagattg ttaaatcaat tcatcaatgc
    47281 gaaaaactct catgacttaa tgaatatctt gcatcatcag gataaggaat tgagagggcg
    47341 tttgttggaa atgatattta ctagccaaaa ctaattgaaa taattagaaa gtcatttgtt
    47401 tagtgtatat gaagattctg tatggtattc gttatcactg gtcacattga aaatgtgaaa
    47461 taagcaccta caacatagac tttacaacac ttcatgtttc atatcatggg gtgtttttct
    47521 atttaagtca aagccaatca aaaaatctca ctattcatca ggttaaagga aacctaatca
    47581 tagtgagatt gtgaattata gtagagtttg tatcgcctct tcaatttgtt ttgggtctgt
    47641 ttttgaagaa aagcgttcaa agacttgccc atcacgacca atgagaaact tagcgaaatt
    47701 ccattcgatt cgttttccta gtgggccaga tttatggtct tttaaccaga catagagagg
    47761 gtctgcttcc ttaccgttga ccttaatctt ggcaaaacgt gggaaggtgg tttgaaaatg
    47821 taggctacag aaggtgttga tttcctctgc gctgccgggt gcttgtccca taaactgatt
    47881 gcaagggaaa tccaatattt cgaagccctg atcttgatag cgttcataga gttcttgaag
    47941 tctctggtac tggggcgtta aaccacatcc agtagcagtg ttgacaatca agagaacttt
    48001 gccacgatag ctatccaagg gagttgcttg gttgttttgg ttcaaaacgg aaaaatcata
    48061 aagtgaagtc atgagggcct cttttctttt tctacattgt aacagttttt acttttttcg
    48121 tcgagtcgga tggaagatat tgttgaagaa taagccctca atatgataga aaacgtttac
    48181 aaataacttt aaaaatggta tgatttaatt aaaccggttt actttgttgc tataaatctc
    48241 taatttgaga tttagttcct attgatttta caatatgttt attggagtgt atacatgcaa
    48301 acaaaaacaa agaagctcat tgtgagtttg tcttcacttg ttttatcagg atttttatta
    48361 aaccattata tgacagttgg agcggaagaa acgactacga ataccattca gcaaagccag
    48421 aaggaagttc agtatcagca aagggataca aaaaatttag ttgaaaatgg tgattttggt
    48481 cagacggagg acggaagcag tccgtggaca ggaagcaaag ctcaggggtg gtcagcttgg
    48541 gtagaccaga agaatagttc tgcagatgcc tcaactcgag tcattgaggc taaggatggg
    48601 gctatcacta tctcaagccc tgagaaatta agggcagcgg ttcaccgtat ggttcctatt
    48661 gaagctaaga aaaagtataa actgcgtttc aagattaaaa cagataataa agtcgggatt
    48721 gccaaggttc gtatcattga ggaaagtggt aaggacaagc gattgtggaa ttctgcaacg
    48781 acgtcaggaa caaaggactg gcagaccatt gaagcagact atagcccgac tttagatgtt
    48841 gataaaatca agctggagtt attctatgaa acaggaactg ggactgtttc ctttaaggat
    48901 attgagctgg tagaggtagc agcccagctt tctgaggatt ctcaaacaga taaacagctt
    48961 gaggaaaaga ttgatttacc aattggaaaa aaacatgttt tttctcttgc ggactatact
    49021 tataaggtag aaaatcctga cgttgcttca gtcaaaaatg gaattttaga acctcttaag
    49081 gaagggacaa ccaatgtcat tgtcagtaaa gatggcaagg aagtgaaaaa gattcctttg
    49141 aagattctag cctctgttaa ggatgcatac acagcccgtt tggatgactg gaatggcatc
    49201 atcgctggga atcaatacta tgattctaaa aatgaacaga tggccaaatt aaaccaggaa
    49261 ttggaaggaa aggtagctga tagcctatct agtatttcaa gtcaggcgga ccgcacctat
    49321 ttgtgggaaa aattttcaaa ttataaaatg tctgcaaatc tgactgccac ttatcggaaa
    49381 ttggaggaga tggccaagca agtgaccaat ccttcttctc gttattatca agatgaaact
    49441 gtcgttcgaa cagtcaggga ttccatggaa tggatgcata aacatgtcta caatcgtgaa
    49501 aagagcattg ttgggaactg gtgggattat gaaatcggta cacctcgtgc catcaacaat
    49561 accttgtctc tgatgaaaga atacttctct gatgaggaaa ttaaaaaata tacagatgtg
    49621 attgaaaaat ttgtaccaga tcccgaacat ttccgaaaga cgactgataa cccatttaag
    49681 gctctaggtg gaaacttagt tgatatggga agagtaaaag taatagctgg tttactgcgt
    49741 aaggatgatc aagaaatttc ttctaccatt cgctcgattg agcaagtgtt caagttggta
    49801 gaccaaggtg aaggttttta tcaagatgga tcctatatcg accacaccaa tgttgcctat
    49861 acgggtgctt atgggaatgt tttgattgat ggcctgtctc aactgttgcc agtcattcaa
    49921 aagaccaaga atccaatcga taaagataaa atgcaaacca tgtaccactg gattgataaa
    49981 tcgtttgctc ctttgctggt gaatggagag ctgatggata tgagtcgtgg acgctcgatc
    50041 agtcgtgcaa atagcgaggg gcacgtggcc gcagtagaag tactaagagg gattcaccga
    50101 atagcggata tgtctgaagg agaaaccaaa caacgtttgc agagtcttgt gaagaccatt
    50161 gttcaatcgg atagttatta tgatgtcttt aagaatttga agacttataa ggatatcagt
    50221 ttgatgcaat ccttgttaag tgatgcagga gtcgcaagtg ttccaagaat aagttaccta
    50281 tctgccttta acaagatgga taaaacagcc atgtacaatg cagagaaagg gtttggattt
    50341 ggcttgtcac tcttttccag tcgtaccttg aattacgaac acatgaacaa ggaaaataaa
    50401 cgtggttggt atacgagtga tgggatgttc tatctttaca atggcgattt gagtcactat
    50461 agcgatggct actggccaac agttaatcca tataagatgc ctggtacaac agagacggat
    50521 gctaagagag cggatagcga tacaggtaaa gttttaccgt ctgctttcgt tggaacgagc
    50581 aaactagatg atgccaatgc gacagcaacc atggatttca ccaactggaa tcaaacattg
    50641 actgctcata agagctggtt tatgctaaag gataagattg cctttttagg aagcaatatc
    50701 caaaacactt caacagatac tgctgcaact acaatcgacc agagaaaact ggaatcaagt
    50761 aatccatata aagtctatgt caatgataaa gaagcctccc ttacagaaca agaaaaggat
    50821 tatcctgaaa cccaaagtgt ctttttagaa tcgtccgatt cgaaaaagaa tattggttac
    50881 tttttcttta agaagagttc aatcagcatg agtaaggctt tgcaaaaggg agcctggaag
    50941 gatatcaatg aaggacagtc agacaaggaa gttgaaaatg aatttcttac gattagtcag
    51001 gctcataagc aaaatggaga ttcttatggc tatatgctca ttcctaacgt ggatcgtgcc
    51061 accttcaatc aaatgataaa agagttagaa agtagcctca tcgaaaataa cgaaaccctt
    51121 cagtctgttt atgatgccaa acaaggagtt tggggcattg tgaaatatga tgattctgtc
    51181 tctactattt ccaaccaatt ccaagttttg aaacgtggag tctataccat tcgaaaagaa
    51241 ggggatgaat ataagattgc ctactataat cctgaaaccc aggaatcagc tccagatcag
    51301 gaagtcttta aaaagctaga gcaagcagct cagccacaag tacagaattc aaaagaaaag
    51361 gaaaaatctg aagaggaaaa gaaccattcg gatcaaaaga atctccctca gacaggagaa
    51421 ggtcagtcaa tcttggcaag tctagggttc ttgctacttg gggcgtttta tctattccgt
    51481 agaggaaaga acaactaatt tgttcatcat ctagatgaat tacatgaaac tgtggaaaat
    51541 agaaaaaatc cgaagaaggc caaatatctt cggatttttc ttttaaaaaa ggataagttg
    51601 atacttatcc tttttacttc attatgtgac tatagcgttt tgaaactaga ataggacatc
    51661 ataactgcta aaagatttct ataaattcat ttgattttcc taatcaattt gttcgtatcc
    51721 tatttcactc cactatatta gtccgtctcg ctccgtgagg tgcgagacaa aacaaccacc
    51781 cgctatacgg gtgcgcgtcg aaggttatac caaaaaaact ccaaacgcga tacaataaag
    51841 gtgttcaatc cacttgtaaa gcgaaaggag aaaaaatatg gcacaaaagg ctcatagttt
    51901 atctcacaca aagtggaggt gttctatcac attgtgttca cccctaagta tagacgaaaa
    51961 gtcatctata atcaatatag aagtagttta ggcgaaatat ttcatcgctt gtgtagttat
    52021 aaaggtgttg aaatgatcga gggtcactta atgccagacc atgtacacat gttagtcagt
    52081 attccgtcga ggctaagtgt ttcaagtttt atggggtatt taaaaggcaa aagtgcactc
    52141 atgatgtttg acaaacacgc caatctcaag tacaagtttg ggaatcggca tttctgggcg
    52201 gaaggttatt atgtaagtcc agtagggctt aatgaagcca caattaagaa atatagtcaa
    52261 gattaaagaa attatccagt ggatgatttc ttcacgagta tgaaaatttg agaacgagta
    52321 aagtatgata tatagtaaaa tgaaataaga acaggacaaa atcgatcagg acagtcaaat
    52381 cgatttttaa caatgtttta gaagtatagg tgtactattt cagtttcaat ctactatagc
    52441 actagataaa ttgagtgtaa aagaatatga ggatcccttt agggatagtg gtaagtaata
    52501 ccaaagtctc ttaaagaggc aagtgacgag tcaagagcaa taaggcttga acaacgtgaa
    52561 agccagcgtc tttaggcgct ggctgatgat ttgggcttat agctctgaga taaaccaccc
    52621 gttagacggg tagttatgat tttatctgag tgtaatatac tgttgggcaa tctcgctgat
    52681 gcggtcaaag ttgccttggg aagcgagttt attgagttcg ccaccaattc caacggcatc
    52741 tgcaccagca gcgaaccatt gagggatgtt gtttaggccg actcctccgg ttaccattac
    52801 ggaaacttgt gggatcggtg ccttgactgc agagatatat gctggactga gagtactacc
    52861 tgggaagagt ttgatgattt cactaccggc ttcaagtgca gtcgtgatct ctgtgagggt
    52921 aatacagcct ggaatgtacg gtgtgctgta gagattgcac attttcgcag tttcagcatg
    52981 gaaagatgga gaaacaacgt aatttgctcc agctagaatg gcatctctag cagttacggc
    53041 atcaagcaca gtacctgcac cgatacaaac actctgatcg tcctgataca agtctacaag
    53101 ttccttgatg atttgtcctg catactgatt ggtataggcg atttcaatag ctttgatacc
    53161 gcccttgata caagcaatcg aggcttgtag tccttcttcc tttgtatttc ctcgaatgac
    53221 agcgacaatt ttctgttttt ttagttcaat aatcgtatct gatttggtca tgtaattctc
    53281 ctaacgaatg atatcttgtg catttgccag taaattttca atactagttg cggaagtgga
    53341 gagatggtct cctggaagag tgcatttgag agttgcgctc gcaactgcaa agtcaatggt
    53401 agtttttagg gaggaatgat ggagtagttg gtaaagggca ccagatataa aggcatcccc
    53461 gctaccaatt cgttgataga ctgcagtttt tagttggaca gactcttcaa atcgttcttc
    53521 cagagcatag gcttgataga catttttgtc ttgctcatca ctagatcgga gggtatggaa
    53581 aatagccttg aaaccatagg cttcttttaa aagtcgcatg cgattttcca cctcttctag
    53641 gctagcactg tctcttggga acatctctag attttgatca tcaatcatga gaggatcaat
    53701 accgaagcaa tagtcagtaa aacgtgcaaa cttagaaaat tcatacttgg cttctaggac
    53761 tgaaatcatc tttgttctca gattgagatc cattgaaacg acaattcctc ggcgcttggc
    53821 ttcttccaag agtaggagaa ggatcgcacg gacctcttga ccgatagcta tggtgattcc
    53881 actaaaatga aaatggctaa tcccctgaaa gagagaatcc atatctagca tgtttggccg
    53941 aatctggctg atactcgtat gcttacgatc gtagaaaact tcactttgac gacaaccaaa
    54001 gccgttctcc aaatagtaga ggccgattcg atcgccaagc cgacagattg aactggtatc
    54061 gatttggtgc tgtttcaaga atgtgagaaa acgatctcca atctcgttgg cagggagtgc
    54121 ggtaaagact ttcgttgaga tacccagggc ttgcaaatta caagcgatgt taatttctga
    54181 tccgccaaaa taagtcgaac tggcaacatg atcgccgata ctggtggcat ctaatggtga
    54241 gattcgaatt aatggttcgc caaacagtaa tattttcgtc atccattagt tcctttctgg
    54301 tttagaatag ctttacttgg ctaatacttc tttcaaataa gcagcgactt catcatcttg
    54361 gcagttttca aagaagtatt cttggaagta tttgccagag atggtgtctt tgaggaagtc
    54421 ttggtcgatt gttttaagga tggtcatcaa atcattgtgg gtgatttgtt tcacctcgtt
    54481 taagatacga gcgttgcgtt gttcagggat tacacgttct cttgggtagc caccgcccat
    54541 ttcttcagca aataagcgtt caaacatcaa tttgagggtc agttctgccc cccagccaaa
    54601 tcctttggca taagggatag acaaggcgtt accaccattg atttgagaat aaaggtaagc
    54661 gtcagttggg tccactgcta gaccacagac aacaccaggg aagctgttta aagcaagcat
    54721 agcccctaca cccgtaccac agccggtaac aacaaagtca actgcctttg tatttaaaag
    54781 gatggcagcc attagtccgt tctgcacata agttaattga ctttctcctt cttctccacg
    54841 cataccatag ttaaataatt ggtagccttt tttatctgtc gcttctttta gactatcgta
    54901 aataatgtga ttcttgctag cttgactatt ttcattgatt aatgcgattt tcataagatc
    54961 ttctttctat ttttactcag gttgttttcc gatgtaggct aagataccgc catctacata
    55021 taggatgtgg ccattgacaa aattgctggc atcactagcg agaaagacag cagggcccat
    55081 caaatcttca ggatttcccc aacgtgcagc aggtgttttt gcaatgatga actggtcaaa
    55141 tgggtggcga gaaccatctt cttgcaactc acgaagaggt gctgtttgag gagtggcaat
    55201 ataacccggt ccaattccgt tacattggat attggcttca ccgtattcag acgcaatgtt
    55261 gcgggtcaac attttcaagc cccctttagc agcagtataa gcgctaactg tttcacgtcc
    55321 cagttcgctc atcatcgaac aaatattgat aatctttcca tgccctttct ttatcataga
    55381 aggaataact gcctttgaaa cgataaatgg tgcgtttaag tcaatatcga tgaccttacg
    55441 gaaatcagcg gcgctcattt cgcacattgg aactcggcgg ataataccag cgttattaac
    55501 gaggatgtca atgacaccaa cctcttgttc gatttgcttg accatggctt ggataccgtc
    55561 ctcgtctgtc acgtcacaga catatccatg ggcttcgatg ccaacttcac gataagcttc
    55621 aatcccttta ttgaccagat cttgattgat atcgttaaag acaatagtag cgccggcttc
    55681 agcgtaggat ttggcaatag caaatccaat tccataagaa gcgccggtga tgagagcaat
    55741 ttttcctttt aaagaaaact gctcaattga gaatgatgta tttgtcattt gatacttcct
    55801 ttcaaatttg ttaagacttc tctataacca aattatattc tagtaaacca gttttgtcaa
    55861 taaataaata tttttattta taaaaagatt tattttcctt aaaaatggaa tattttgaaa
    55921 tttctgtcta ttagaatgat taaaaagata atgaaagcgc taatattttt ttaaaaaaac
    55981 tattgacaag ataaaaataa aggattacaa tggggaatat aaagtaaacc ggtaaaccta
    56041 aacaagaaag gagaaaagat gaaaattgta cttgtagggc atggacattt tgctacaggg
    56101 atttatagtt ctttacaatt gattgcaggc aatcaagaaa atgtggaggc aattgacttt
    56161 gtggaaggaa tgtcagcaga tgaactcaag caaaaaatct tacttgcaat ttcaaatgaa
    56221 gaagaagttt taatcctaag tgatctcttg ggaggatcgc cattcaaggt ttcttctacc
    56281 ataatgggag aaaatccagc caaaacaatg aatgttcttt cgggtttgaa cttagccatg
    56341 ttaatggaag cagtctttgc tagaatggct catagctttg atgaggttgt taataaatca
    56401 gtagtggcgg cccagggcgg agtcgtaaat ggtaaagaat tgttttcaac ggatgcagag
    56461 gaagaggaag aagatttcga atcgggtatt taaagggtaa aagaatgata aaaaaggtta
    56521 cgattgaaaa aataaaatcg cctgagcgct tcttagaagt accacttctg acgaaagaag
    56581 aagtcggcca ggcaatcgat aaggttattc ggcagttaga actcaacctt gactatttca
    56641 aggaagattt cccgacgcca gctacctttg ataatgtcta tccaatcatg gataacacgg
    56701 aatggaccaa tggtttctgg acaggagaac tgtggttggc ttatgaatac agtcaacagg
    56761 atgcatttaa aaacatcgct cataaaaatg ttctttcttt cctggatcgt gtcaataaga
    56821 gagtagaatt ggatcaccat gatctcggct tcttgtacac accgtcttgt atggctgaat
    56881 ataagataaa tggagatgga gaggctagag aagcaacctt gaaagctgca gataagttga
    56941 ttgaacgcta tcaagaaaaa ggtggtttta ttcaagcttg gggagacttg ggcaagaaag
    57001 agcattaccg tttgattatc gactgcttgc tcaatatcca actcttattc tttgcttatc
    57061 aagaaacagg cgatcaaaaa tactacgata ttgcagaaag tcatttctat gcttcagcta
    57121 ataatgtaat ccgtgatgac gcttcgtcct tccacacctt ctattttgat cctgagacag
    57181 gtcaaccctt taaaggtgta acgagacaag ggtatagtga tgattcatgc tgggcacgtg
    57241 gtcaatcatg gggagtctat ggtattcctt tgacttatcg tcacttaaaa gacgagtcct
    57301 gctttgactt gtttaagggt gtgaccaatt atttcttgaa tcgtctgcca aaagatcatg
    57361 tgtcctattg ggatttgatt tttaatgatg gtagtgctca atcacgagat tcttcagcaa
    57421 cagctatcgc cgtctgtggg attcatgaaa tgctaaaaca tctcccagag gtggatgctg
    57481 acaaagatat ttataaacat gctatgcatg ccatgcttcg ttccttgatc gaacattatg
    57541 caaatgatca atttacccct ggtgggacaa gtctcctcca cggtgtgtac tcatggcatt
    57601 caggtaaagg agtggatgaa ggcaatatct ggggtgacta ctattaccta gaagccctta
    57661 tccgtttcta caaagactgg aacctatatt ggtaggagga gaaatatgac aatgccaaat
    57721 attattatga cccgtatcga tgaacggttg attcatgggc aaggacaact ttgggtaaaa
    57781 tacctaggtt gtaatacggt cattgttgcc aatgacgaag taagcacgga caagatgcaa
    57841 caaactctga tgaaaacagt tgtgccagac tcagttgcca tgcgtttctt ccctttgcaa
    57901 aaggtgattg atatcattca caaggctaat cctgctcaaa cgatctttat cgttgtaaag
    57961 gatgtgaagg atgctttaac cttggtagaa ggtggtgtcc ctatcaaaga aatcaatatt
    58021 gggaacattc acaatgctac tggtaaagag caagtgacac gctccatctt cctgggtgaa
    58081 gaggacaagg cggccctcaa ggaattgagc caaactcatc aagtaacatt taatacgaaa
    58141 acaactccaa caggaaatga tggagctgtt caagtcaaca ttatggacta tatttaaaag
    58201 aggagatcgt tatgtcgatt aatgtatttc aagcgatttt aattggatta tggacagctt
    58261 tctgttttag tggaatgctg ttaggaattt acaccaatag atgtattgtt ctgtcatttg
    58321 gtgtcggaat tattctaggt gatctgccta ctgctcttgc aatgggagct attggtgaat
    58381 tggcttatat gggattcggt gttggtgctg gaggtactgt tccaccaaac ccaatcggac
    58441 ctggtatctt tggtaccttg atggctatca ctagtgctgg taaagtcagt ccagaagcgg
    58501 ctcttgccct ctctactccg attgctgtgg cgattcaatt cttacaaact ttcgcctaca
    58561 ctgtacgtgc tggtgcgcct gaaacagcga tgaagcactt gaaaaaccat aatttgaaga
    58621 aattcaagtt cactctaaat gcaacaattt ggttgtttgc ctttattgga tttaccttgg
    58681 gttgcttggg tgccctttca atggatacct tgttgaaact cgtagactac attccaccgg
    58741 tattgcttac aggtttgaca gttgctggta aaatgctccc agctatcggt tttgcgatga
    58801 tcttgtcagt gatggctaag aaagagttga ttccctttgt cttgttggga tatgtttgtg
    58861 cagcttatct aaacatccca acaattggta ttgcaattgt aggtactatc tttgctttga
    58921 ttgaatttta taacaagcca aaaacagcgg atcatgtggt agaggaggaa gcacacgatg
    58981 actggatcta acaaattaac aaaacgtgat tatcttaaaa cgtctttgcg ggcattcttt
    59041 tgtcaaaatg gatttaacta tagtaactat caagggttgg gatatgccaa tgtgatgtat
    59101 cctgctttga aaaaacacta tggagaggat caggaaggtt tctaccaagc cttggaagaa
    59161 aactgtgaat tctataatac caacccacac ttcctgcctt ttattaccag cttgcatctt
    59221 gtaatgttgg aaaatggccg tccggcaaaa gaaacacgta gcatcaagat ggccttgatg
    59281 ggaccattgg caggtattgg ggattctctt tctcaattct gtttagctcc attgttctca
    59341 accatcgcag cttcgtttgc tcaagaaggc ttggttgtcg gtccaatctt gttcttcctt
    59401 gcgatgaata cgattttaac agcgattaaa ttgtcaactg gtctgtatgg atacaaacta
    59461 ggaacaactg tgattgataa actaagcgaa cagatggcaa cgatttctcg tattgccaat
    59521 attatcggtg taaccgtaat tgctggtttg gcagcgacat ctgttaagat tatggtgccg
    59581 attacctttg ctgcagggga agttaaagca gacgctaaac aaagtatcgt aagtattcag
    59641 ggaatgcttg ataaggttgc tccagctctt ctaccagccc tatttacact tttagtttac
    59701 tacttgatca aagaaaagaa atggacaaca tataaactcg ttattttaac agttatcatc
    59761 ggaattatcg gaagctggct taagattata gcttaatgga tacaacattg ttttatggaa
    59821 tagtgattgt cttggcagtg agtccccttt tactgtcaag ctttcattct attcgtcagc
    59881 aaaagttgct tcgcaaacag atggagcaac gacaagagta tttagcttct ttaacatctg
    59941 gtgatgaagt gttgttattg tctggaattc atggaaaaat catttctatc caagatgact
    60001 tggtctcctt gcagattgca aaaggtgtgg tcatctatgt agaaaaggaa agtgtaatgg
    60061 gaaagacaaa agaactgctt tttaagtagt tctttttctg gtaatagata atgaaagaag
    60121 aaagaagaca attttttgaa agagtcgatg gaaaccaatg tcgtgattat atcttgtccc
    60181 actgttcaaa agactatgag aaagtcaaga gttcccttga acgcttgata gacaatcgtt
    60241 ttatgtttga tagtccttgg gatatggagc cttgttcaaa aatccatcaa atccagccga
    60301 tggtatggga tcaagtattt gaagatgatc cagaatggtc ttatatgctc aatcgacaag
    60361 aatatctctt gcagtttatg atagggtatc tggtagaagg agataagggc tatatccaaa
    60421 agtgcaagtt ctttctattt gattggattg agcaggtgag agaattttct cctcaatcct
    60481 tgatgactag aaccttggat acgggtattc gttcctttac ttggttgaaa ctactcttgc
    60541 tcctcttgaa atttgacttg ctagaggaga aagaactaga gaaaattttg gtcagtctag
    60601 aaaagcagat tgactttatg aaaagccact atcgcgccaa gtacaccctt agtaactggg
    60661 ggattttaca aacaattccg atgcttgcta tctattattt cttttcagat aagatggacc
    60721 tagaagaagc ttaccatttt gcttcagagg agttgaaaca gcaaattgag acacagattt
    60781 taggagatgg aagccagttt gaacagtcga ttctctatca tgtagaggtt tataaagcct
    60841 tgctggattt gtgtctcttg cttccagact tgcaagatag ttaccgagag ttgctggaaa
    60901 agatggcgac ctatattcaa atgatgacag gcttagatgg acgaactttg gcttttggtg
    60961 atagcgattc tacagaaacg acagaaattt tgagcctgtc tgctgtggtt ttgaacaagg
    61021 aagaccttct taacggtctg gatgttaaag tcgatttgct tagcctcttg ttcctggggc
    61081 gagaaaaggt caagcgactg caggaatttg aaaggagagc ttggcagcct aagtccatga
    61141 tctttgaaga ctctggacat gtctgcatta aggatgaaca tcgttatcta tttttcaaaa
    61201 atggtccgct aggaagtgcc catagccata gtgacgagaa tagtttttgc ttacagtatc
    61261 aaggccaacc tattttcata gatgctgggc gttattctta tcgggagata tatgaacgtt
    61321 atctcttaaa gagtgcttgg agtcattcga cctgcattgt agatgggaaa gctccggaaa
    61381 gaatcacggg atcctgggaa tatgaatact atcctcactc cctgttttgt caccataaag
    61441 aaagggaggg agtgcattat attgaggggg cttattggtc agcagaacct gatttgcctt
    61501 atcttcacaa gagaaaaatc ctcatgttgg tagaggatgt ctggctcttg gtagatgaca
    61561 tcaggtgtca aggtcagcat gaggcgttga ctcagtttat ccttgacaag gatgtgacct
    61621 atcaagatgg gaaaatcaat cagttgagac tatggagtga agttgatttt gatttggaag
    61681 ataccatcat ttctcctaaa tacaatgagc ttgaaagaag tagcaaactc accaagcgcc
    61741 aattctttga gaatcagatg ctggattata ccatcattgc gcatgagagt tttgaaatta
    61801 tccgtcattc tgtctaccag acagatgatc gtgaagtgga aaatgctctg gcttttgaag
    61861 tgaaaaatga cgaaacagac aagctgattc tgttattaag cgaggatatt ggtgtaggtg
    61921 aaaaattgtg cctcgttgac ggaacaaaaa tgcgtggaaa atgtctagta tatgataaaa
    61981 taaatgagag aatgattcgc ttgcagtgct agaaataggc attttgaata gtgaatatgt
    62041 tataataagt attagtagga ggtgttttag attggagaag aaactgacca taaaagacat
    62101 tgcggaaatg gctcagacct cgaaaacaac cgtgtcattt tacctaaacg ggaaatatga
    62161 aaaaatgtcc caagagacac gtgaaaagat tgaaaaagtt attcatgaaa caaattacaa
    62221 accgagcatt gttgcgcgta gcttaaactc caaacgaaca aaattaatcg gtgttttgat
    62281 cggtgatatt accaacagtt tctcaaacca aattgttaag ggaattgagg atatcgccag
    62341 ccagaatggc taccaggtaa tgataggaaa tagtaattac agccaagaga gtgaggaccg
    62401 gtatattgaa agcatgcttc tcttgggagt agacggcttt attattcagc cgacctctaa
    62461 tttccgaaaa tattctcgta tcatcgatga gaaaaagaag aaaatggtct tttttgatag
    62521 tcagctctat gaacaccgga ctagctgggt taaaaccaat aactatgatg ccgtttatga
    62581 catgacccag tcctgtatcg aaaaaggtta tgaacatttt ctcttgatta cagcggatac
    62641 gagtcgtttg agtactcgga ttgagcgggc aagtggtttt gtggatgctt taacagatgc
    62701 taatatgcgt cacgccagtc taaccattga agataagcat acgaatttgg aacaaattaa
    62761 ggaattttta caaaaagaaa tcgatcccga tgaaaaaact ctggtattta tccctaactg
    62821 ttgggcccta cctctagtct ttaccgttat caaagagttg aattataact tgccacaagt
    62881 tgggttgatt ggttttgaca atacggagtg gacttgcttt tcttctccaa gtgtttcgac
    62941 gctggttcag ccctcctttg aggaaggaca acaggctaca aagattttga ttgatcagat
    63001 tgaaggccgc aatcaagaag aaaggcaaca agtcttggat tgtagtgtga attggaaaga
    63061 gtcgactttc taaaatgaag gaaaatgact tgcaatttct gttaagaaat aaaataatcc
    63121 cacctagaac aagctaggtg ggattatttg cctatgaaat gagaaattat gggagcaagc
    63181 tcctaaatca actgtttttg atctacttct ttaactactt gataaaagtt atagaagtag
    63241 gccaaacttg aaatgatggt tacgactagg aatattgaaa atttccattg gacagggttg
    63301 gttaaaagtt gtggaaagga tatgaggaga aagaagaggg ctgcgttgag gacaggtatc
    63361 cgttttgatt gtattttctc aagtccttta ttgagcgcag gaagaaagag gagtaggagt
    63421 agtaaaactg tatgagaaac agctcctgaa ataagggcga agaaaaggaa aatactgata
    63481 aaaacatgaa tgatcagtag tctagctagt gatttcataa ggcacctcct aatcctggtc
    63541 ttttttagct cttgcaatac gaagtgagtc gacaatatgt atcatcactc cgaaaaagaa
    63601 agctcccagt atagttttaa aaatatgttt tgtatttaga agagaactga taaaatttgg
    63661 attttcactt gttagggtat caatgagtgg aattataaaa aatatcactg ttccataaat
    63721 cgaacctgct ttcagaccag gataacgtaa ctgtttcttt tcttttttca tgagtttgct
    63781 ccttttttaa aaatcttcct tccaaaagag actgttgagg tcagtttgga ggctgcgagc
    63841 gagattgaga cagagttcca gagttggatt gtacttgtcg ttttcaatca tattgatggt
    63901 ctgtctcgag acaccgatat ccttggcgag ctcgagctgg gaaatgccca gttccttgcg
    63961 aaattctttc acacgattca tctggtctcc tttctgattt gtgtcgtata tatttgactt
    64021 tattatagtc ttttaaacat aaagtgtcaa gtatttttga catatttttt gaagaaatag
    64081 tagtctcctt gtcctatttg tctgacaagt gcaagctggt cggatttgtg gtaaaataga
    64141 taagatatga caaaagaatt tcatcatgta acggtcttac tccacgaaac gattgatatg
    64201 cttgacgtaa aacctgacgg tatctacgtt gatgcgactt tgggtggagc aggccatagc
    64261 gagtatttat taagtaaatt aagtgaaaaa ggccatctct atgcctttga ccaggatcag
    64321 aatgccattg acaatgcgca aaaacgcttg gcaccttaca ttgagaaggg aatggtgacc
    64381 tttatcaagg acaacttccg tcatttacag gcacgtttgc gcgaagctgg tgttcaggaa
    64441 attgatggaa tttgttatga cttgggagtg tctagtcctc aattagacca gcgtgagcgt
    64501 ggtttttctt ataaaaagga tgcgccactg gacatgcgga tgaatcagga tgctagtctg
    64561 acagcctatg aagtggtgaa caattatgac tatcatgact tggttcgtat tttcttcaag
    64621 tatggagagg acaaattctc taaacagatt gcgcgtaaga ttgagcaagc gcgtgaagtg
    64681 aagccgattg agacaacgac tgagttagca gagattatca agttggtcaa acctgccaag
    64741 gaactcaaga agaagggtca tcctgctaag cagattttcc aggctattcg aattgaagtc
    64801 aatgatgaac tgggagcggc agatgagtcc atccagcagg ctatggatat gttggctctg
    64861 gatggtagaa tttcagtgat tacctttcat tccttagaag accgcttgac caagcaattg
    64921 ttcaaggaag cttcaacagt tgaagttcca aaaggcttgc ctttcatccc agatgatctc
    64981 aagcccaaga tggaattggt gtcccgtaag ccaatcttgc caagtgcgga agagttagaa
    65041 gccaataacc gctcgcactc agccaagttg cgcgtggtca gaaaaattca caagtaagag
    65101 ggaaaaagat ggcagaaaaa atggaaaaaa caggtcaaat actacagatg caacttaaac
    65161 ggttttcgcg tgtggaaaaa gctttttact tttccattgc tgtaaccact cttattgtag
    65221 ccattagtat tatttttatg cagaccaagc tcttgcaagt gcagaatgat ttgacaaaaa
    65281 tcaatgcgca gatagaggaa aagaagaccg aattggacga tgccaagcaa gaggtcaatg
    65341 aactattacg tgcagaacgt ttgaaagaaa ttgccaattc acacgatttg caattaaaca
    65401 atgaaaatat tagaatagcg gagtaagata tgaagtggac aaaaagagta atccgttatg
    65461 cgaccaaaaa tcggaaatcg ccggctgaaa acagacgcag agttggaaaa agtctgagtt
    65521 tattatctgt ctttgttttt gccatttttt tagtcaattt tgcggtcatt attgggacag
    65581 gcactcgctt tggaacagat ttagcgaagg aagctaagaa ggttcatcaa accacccgta
    65641 cagttcctgc caaacgtggg actatttatg accgaaatgg agtcccgatt gctgaggatg
    65701 caacctccta taatgtctat gcggtcattg atgagaacta taagtcagca acgggtaaga
    65761 ttctttacgt agaaaaaaca caatttaaca aggttgcaga ggtctttcat aagtatctgg
    65821 acatggaaga atcctatgta agagagcaac tctcgcaacc taatctcaag caagtttcct
    65881 ttggagcaaa gggaaatggg attacctatg ccaatatgat gtctatcaaa aaagaattgg
    65941 aagctgcaga ggtcaagggg attgatttta caaccagtcc caatcgtagt tacccaaacg
    66001 gacaatttgc ttctagtttt atcggcctag ctcaactcca tgaaaatgaa gatggaagca
    66061 agagcttgct gggaacctct ggaatggaga gttccttgaa cagtattctt gcagggacag
    66121 acggcattat tacctatgaa aaggatcgtc tgggtaatat tgtacccgga acagaacaag
    66181 tttcccaacg aacgatggac ggtaaggatg tttatacaac catttccagc cccctccagt
    66241 cctttatgga aacccagatg gatgcttttc aagagaaggt aaaaggaaag tacatgacag
    66301 cgactttggt cagtgctaaa acaggggaaa ttctggcaac aacgcaacga ccgacctttg
    66361 atgcagatac aaaagaaggc attacagagg actttgtttg gcgtgatatc ctttaccaaa
    66421 gtaactatga gccaggttcc actatgaaag tgatgatgtt ggctgctgct attgataata
    66481 atacctttcc aggaggagaa gtctttaata gtagtgagtt aaaaattgca gatgccacga
    66541 ttcgagattg ggacgttaat gaaggattga ctggtggcag aatgatgact ttttctcaag
    66601 gttttgcaca ctcaagtaac gttgggatga ccctccttga gcaaaagatg ggagatgcta
    66661 cctggcttga ttatcttaat cgttttaaat ttggtgttcc gacccgtttc ggtttgacgg
    66721 atgagtatgc tggtcagctt cctgcggata atattgtcaa cattgcgcaa agctcatttg
    66781 gacaagggat ttcagtgacc cagacgcaaa tgattcgtgc ctttacagct attgctaatg
    66841 acggtgtcat gctggagcct aaatttatta gtgccattta tgatccaaat gatcaaactg
    66901 ctcggaaatc tcaaaaagaa attgtgggaa atcctgtttc taaagatgca gctagtctaa
    66961 ctcggactaa catggttttg gtagggacgg atccggttta tggaaccatg tataaccaca
    67021 gcacaggcaa gccaactgta actgttcctg ggcaaaatgt agccctcaag tctggtacgg
    67081 ctcagattgc tgacgagaaa aatggtggtt atctagtcgg ggtaaccgac tatattttct
    67141 cggctgtatc gatgagtccg gctgaaaatc ctgattttat cttgtatgtg acggtccaac
    67201 aacctgaaca ttattcaggt attcagttgg gagaatttgc caatcctatc ttggagcggg
    67261 cttcagctat gaaagactct ctcaatcttc aaacaacagc taaagctttg gagcaagtaa
    67321 gtcaacaaag tccttatcct atgcctagtg tcaaggatat ttcacctggt gatttagcag
    67381 aagaattgcg tcgcaatctt gtacaaccca tcgttgtggg aacaggaacg aagattaaaa
    67441 acagttctgc tgaagaaggg aagaatcttg ccccgaacca gcaagtcctt atcttatctg
    67501 ataaagtaga ggaagttcca gatatgtatg gttggacaaa ggagactgct gagacccttg
    67561 ctaagtggct caatatagaa cttgaatttc aaggttcggg ctctactgtg cagaagcaag
    67621 atgttcgtgc taacacagct atcaaggaca ttaaaaaaat tacattaact ttaggagact
    67681 aatatgttta tttccctcag tgctggaatt gtgacatttt tactaacttt agtaggaatt
    67741 ccggccttta tccaatttta tagaaaggcg caaattacag gccagcagat gcatgaggat
    67801 gtcaaacagc atcaggcaaa agctgggact cctacaatgg gaggtttggt tttcttgatt
    67861 acttctgttt tggttgcttt ctttttcgcc ctatttagta gccaattcag caataatatg
    67921 ggaatgattt tgttcatctt ggtcttgtat ggcttggtcg gatttttaga tgactttctc
    67981 aaggtctttc gtaaaatcaa tgaggggctt aatcctaagc aaaaattagc tcttcagctt
    68041 ctaggtggag ttatcttcta tcttttctat gagcgcggtg gcgatatcct gtctgtcttt
    68101 ggttatccag ttcatttggg atttttctat attttcttcg ctcttttctg gctagtcggt
    68161 ttttcaaacg cagtaaactt gacagacggt gttgacggtt tagctagtat ttccgttgtg
    68221 attagtttgt ctgcctatgg agttattgcc tatgtgcaag gtcagatgga tattcttcta
    68281 gtgattcttg ccatgattgg tggtttgctc ggtttcttca tctttaacca taagcctgcc
    68341 aaggtcttta tgggtgatgt gggaagtttg gccctaggtg ggatgctggc agctatctct
    68401 atggctctcc accaagaatg gactctcttg attatcggaa ttgtatatgt ttttgaaaca
    68461 acttctgtta tgatgcaagt cagttatttc aaactgacag gtggtaaacg tattttccgt
    68521 atgacgcctg tacatcacca ttttgagctt gggggattgt ctggtaaagg aaatccttgg
    68581 agcgagtgga aggttgactt cttcttttgg ggagtgggac ttctagcaag tctcctgacc
    68641 ctagcaattt tgtatttaat gtaagaatgg caccctgatg tttcagggtg tttttgtatt
    68701 taaatacaca atgaaaatca aagaacaaac tagaaagcta actttaggct gctcaaaata
    68761 tagtagattg aaactagaat agtacacatc tgcttctaaa atattgttag aaatcgattt
    68821 gactgtcctg atcgatttgt cctgttctta tttcatttta atatatagtt ttgagatggt
    68881 tgatagaact gacgaagtca gctcaaaaca tggttttgag gttgtagata aggagaagct
    68941 gatgtggttt gaagaggttt tcgaagagtg taaaaaaata ttggtcagtt aaagtcaaaa
    69001 ctcttgacct tttctgacca atgtagtata ttatgaacgt aaggtaaatg aaagccttac
    69061 tagaacactt atttaaagta aaatagaaag aggtgggtct atgtttcatc tagaaatttt
    69121 cagaagtaaa gatagtctac tcctgcttga aaaagaaaaa ccagaaatag tacgtagggt
    69181 agcggtttag ctagtctaaa ttttttaaaa caatggtcaa agatagtcaa tatcagtagt
    69241 cataactaag taaacaaaaa gaggtaaaga atatgaataa caactttaat aattttaata
    69301 acatggatga tttatttaac caattgatgg gtggtatgcg aggatatagt tctgaaaatc
    69361 gccgttactt aattaatgga cgcgaagtca cacctgagga atttgctcac tatcgtgcga
    69421 ctggtcaatt accaggaaat gcagaaactg atgtgcaaat gccacaacag gcatcaggta
    69481 tgaaacaaga cggtgtcctt gcaaaactag gtcgaaactt ggcagcagaa gcgcgtgagg
    69541 gcaagttgga tcctgttatc ggacgaaaca aggaaattca agaaacatct gaaatcctct
    69601 cacgtcgcac caagaacaat cctgttttgg tcggagatgc aggtgttggt aagacagcag
    69661 ttgtcgaagg tctagcgcaa gccattgtga acggagatgt tcctgctgct atcaagaaca
    69721 aggaaattat ttctattgat atctcaggtc ttgaggctgg tactcaatac cgtggtagct
    69781 ttgaagaaaa tgtccaaaac ttagtcaatg aagtgaaaga agcagggaat attatcctct
    69841 tctttgatga aattcaccaa attcttggtg ctggtagcac tggtggagac agtggttcta
    69901 aaggacttgc ggatattctc aagccagctc tctctcgtgg agaattgaca gtgattgggg
    69961 caacaactca agacgaatac cgtaacacca tcttgaagaa tgctgctctt gctcgtcgtt
    70021 tcaacgaagt gaaggtcaat gctccttcag cagagaatac ttttaaaatt cttcaaggca
    70081 ttcgtgacct ctatcaacaa caccacaatg tcatcttgcc agacgaagtc ttgaaagcag
    70141 cggtggatta ttctgttcaa tacattcctc aacgtagctt gccagataag gctattgacc
    70201 ttgtcgatgt aacggctgct cacttggcgg ctcaacatcc agtaacagat gtgcatgctg
    70261 ttgaacgaga aatcgaaacg gaaaaagaca agcaagaaaa agcagttgaa gcagaagatt
    70321 ttgaagcagc tctaaactat aaaacacgca ttgcagaatt ggaaaagaaa atcgaaaacc
    70381 acacagaaga tatgaaagtg actgcaagtg tcaacgatgt ggctgaatct gtggaacgaa
    70441 tgacaggtat cccagtatcg caaatgggag cttcagatat cgaacgtttg aaagatatgg
    70501 ctcatcgctt gcaagacaag gtgattggtc aagataaggc cgtagaagct gtagctcgtg
    70561 ctatccgtcg taaccgtgct ggttttgatg aaggaaatcg cccaatcggc agcttcctct
    70621 ttgtagggtc tactggggtt ggtaagacgg agcttgctaa gcaattggca ctcgatatgt
    70681 ttggaaccca ggatgcgatt atccgtttgg atatgtctga atacagtgac cgcacagctg
    70741 tttctaagct aattggtaca acagcaggct atgtgggtta tgatgacaat agcaatacct
    70801 taacagaacg tgttcgtcgc aatccatact ctatcattct cttggatgaa attgaaaagg
    70861 ctgaccctca agttattacc cttctcctcc aagttctaga tgatggtcgt ttgacagatg
    70921 gtcaaggaaa tacagtaaac ttcaagaaca ctgtcattat tgcgacctca aatgctggat
    70981 ttggctatga agccaacttg acagaagatg cggataaacc agaattgatg gaccgtttga
    71041 aacccttctt ccgtccagaa ttcctcaacc gctttaatgc agtcatcgaa ttctcacact
    71101 tgactaagga agacctttct aagattgtag atttgatgtt ggctgaagtt aaccaaacct
    71161 tggctaagaa agacattgac ttggtagtca gtcaagcggc taaagattat atcacagaag
    71221 aaggttacga cgaagtcatg ggagttcgtc ctctccgtcg agtggttgaa caagaaattc
    71281 gtgataaggt gacagacttc cacttggatc atttagatgc taaacatctg gaagcagata
    71341 tggaagatgg tggtttggtc attcgtgaaa aatcctaata ctcttcgaaa atcaaattca
    71401 aaccacgtca acgtcgcctt gccgtactca agtacagcct gcggctagtt tcctagtttg
    71461 ctctttgatt ttcattgagt ataagataga attttgagga taaaaaagaa ggagccagct
    71521 gaaaaaaact ggttcctttt gaggtacgac gggcatgtcg tgcagtagag atgtact
//
LOCUS       DAVLCS010000006        68400 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLCS010000006 DAVLCS010000000
VERSION     DAVLCS010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.006"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(66..1688)
                     /gene="groL"
                     /locus_tag="VXC78_000437"
     CDS             complement(66..1688)
                     /gene="groL"
                     /locus_tag="VXC78_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV0582583.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISNRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1704..1988)
                     /gene="groES"
                     /locus_tag="VXC78_000438"
     CDS             complement(1704..1988)
                     /gene="groES"
                     /locus_tag="VXC78_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV0582584.1"
                     /translation="MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2161..2556)
                     /locus_tag="VXC78_000439"
     CDS             complement(2161..2556)
                     /locus_tag="VXC78_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0582585.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2634..3395)
                     /locus_tag="VXC78_000440"
     CDS             complement(2634..3395)
                     /locus_tag="VXC78_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0582586.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(3428..4057)
                     /locus_tag="VXC78_000441"
     CDS             complement(3428..4057)
                     /locus_tag="VXC78_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV0582587.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKKENG
                     ETVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEI
                     VEMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPG
                     ELRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(4073..4390)
                     /locus_tag="VXC78_000442"
     CDS             complement(4073..4390)
                     /locus_tag="VXC78_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV0582588.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4387..4686)
                     /locus_tag="VXC78_000443"
     CDS             complement(4387..4686)
                     /locus_tag="VXC78_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV0582589.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(4971..5162)
                     /locus_tag="VXC78_000444"
     CDS             complement(4971..5162)
                     /locus_tag="VXC78_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV0582590.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5323..5997)
                     /locus_tag="VXC78_000445"
     CDS             complement(5323..5997)
                     /locus_tag="VXC78_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582591.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTAKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(6003..6449)
                     /locus_tag="VXC78_000446"
     CDS             complement(6003..6449)
                     /locus_tag="VXC78_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0582592.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6563..7066)
                     /locus_tag="VXC78_000447"
     CDS             complement(6563..7066)
                     /locus_tag="VXC78_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0582593.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISVACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7063..7425)
                     /locus_tag="VXC78_000448"
     CDS             complement(7063..7425)
                     /locus_tag="VXC78_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV0582594.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQKIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7491..9356)
                     /locus_tag="VXC78_000449"
                     /pseudo
     CDS             complement(7491..9356)
                     /locus_tag="VXC78_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(9366..9836)
                     /locus_tag="VXC78_000450"
     CDS             complement(9366..9836)
                     /locus_tag="VXC78_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0582595.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVRFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(9960..10676)
                     /locus_tag="VXC78_000451"
     CDS             complement(9960..10676)
                     /locus_tag="VXC78_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0582596.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11559..12974)
                     /gene="ply"
                     /locus_tag="VXC78_000452"
     CDS             complement(11559..12974)
                     /gene="ply"
                     /locus_tag="VXC78_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV0582597.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(12985..13317)
                     /locus_tag="VXC78_000453"
     CDS             complement(12985..13317)
                     /locus_tag="VXC78_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582598.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13388..13996)
                     /locus_tag="VXC78_000454"
     CDS             complement(13388..13996)
                     /locus_tag="VXC78_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582599.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14009..14467)
                     /locus_tag="VXC78_000455"
     CDS             complement(14009..14467)
                     /locus_tag="VXC78_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV0582600.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14592..15045
                     /locus_tag="VXC78_000456"
                     /pseudo
     CDS             14592..15045
                     /locus_tag="VXC78_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15722..15982)
                     /locus_tag="VXC78_000457"
     CDS             complement(15722..15982)
                     /locus_tag="VXC78_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582601.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(16041..16592)
                     /locus_tag="VXC78_000458"
     CDS             complement(16041..16592)
                     /locus_tag="VXC78_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582602.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(16582..17577)
                     /locus_tag="VXC78_000459"
     CDS             complement(16582..17577)
                     /locus_tag="VXC78_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582603.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(17985..18410)
                     /locus_tag="VXC78_000460"
     CDS             complement(17985..18410)
                     /locus_tag="VXC78_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582604.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEVASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(18554..18922)
                     /locus_tag="VXC78_000461"
     CDS             complement(18554..18922)
                     /locus_tag="VXC78_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582605.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKVMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKK"
     gene            complement(18944..19150)
                     /locus_tag="VXC78_000462"
     CDS             complement(18944..19150)
                     /locus_tag="VXC78_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582606.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(19137..19298)
                     /locus_tag="VXC78_000463"
     CDS             complement(19137..19298)
                     /locus_tag="VXC78_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0582607.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(19656..20612)
                     /gene="lytA"
                     /locus_tag="VXC78_000464"
     CDS             complement(19656..20612)
                     /gene="lytA"
                     /locus_tag="VXC78_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0582608.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(20988..22358)
                     /locus_tag="VXC78_000465"
     CDS             complement(20988..22358)
                     /locus_tag="VXC78_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0582609.1"
                     /translation="MNKKRTVDLIHGPILLSLLSFAFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(22665..23831)
                     /gene="recA"
                     /locus_tag="VXC78_000466"
     CDS             complement(22665..23831)
                     /gene="recA"
                     /locus_tag="VXC78_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV0582610.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(23886..25142)
                     /locus_tag="VXC78_000467"
     CDS             complement(23886..25142)
                     /locus_tag="VXC78_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV0582611.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FTLRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(25226..26242)
                     /locus_tag="VXC78_000468"
     CDS             complement(25226..26242)
                     /locus_tag="VXC78_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0582612.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(26250..26768)
                     /locus_tag="VXC78_000469"
     CDS             complement(26250..26768)
                     /locus_tag="VXC78_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0582613.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEATEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(26758..27201)
                     /gene="tsaE"
                     /locus_tag="VXC78_000470"
     CDS             complement(26758..27201)
                     /gene="tsaE"
                     /locus_tag="VXC78_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV0582614.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVVILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(27287..27907)
                     /locus_tag="VXC78_000471"
     CDS             complement(27287..27907)
                     /locus_tag="VXC78_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582615.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(28290..29153)
                     /locus_tag="VXC78_000472"
     CDS             complement(28290..29153)
                     /locus_tag="VXC78_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0582616.1"
                     /translation="MSTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIQAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            29499..31514
                     /locus_tag="VXC78_000473"
     CDS             29499..31514
                     /locus_tag="VXC78_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0582617.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            31516..32148
                     /locus_tag="VXC78_000474"
     CDS             31516..32148
                     /locus_tag="VXC78_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582618.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(33077..33490)
                     /gene="ndk"
                     /locus_tag="VXC78_000475"
     CDS             complement(33077..33490)
                     /gene="ndk"
                     /locus_tag="VXC78_000475"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV0582619.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIGQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(33601..37278)
                     /gene="rpoC"
                     /locus_tag="VXC78_000476"
     CDS             complement(33601..37278)
                     /gene="rpoC"
                     /locus_tag="VXC78_000476"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV0582620.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(37311..40922)
                     /gene="rpoB"
                     /locus_tag="VXC78_000477"
     CDS             complement(37311..40922)
                     /gene="rpoB"
                     /locus_tag="VXC78_000477"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0582621.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            41338..41408
                     /locus_tag="VXC78_000478"
     tRNA            41338..41408
                     /locus_tag="VXC78_000478"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41370..41372,aa:Cys,seq:gca)
     gene            complement(41606..42937)
                     /locus_tag="VXC78_000479"
     CDS             complement(41606..42937)
                     /locus_tag="VXC78_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV0582622.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(43228..44052)
                     /gene="endA"
                     /locus_tag="VXC78_000480"
     CDS             complement(43228..44052)
                     /gene="endA"
                     /locus_tag="VXC78_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV0582623.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(44091..44279)
                     /locus_tag="VXC78_000481"
     CDS             complement(44091..44279)
                     /locus_tag="VXC78_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0582624.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(44272..45555)
                     /gene="murA"
                     /locus_tag="VXC78_000482"
     CDS             complement(44272..45555)
                     /gene="murA"
                     /locus_tag="VXC78_000482"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0582625.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(45579..45809)
                     /locus_tag="VXC78_000483"
     CDS             complement(45579..45809)
                     /locus_tag="VXC78_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV0582626.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(45867..46904)
                     /locus_tag="VXC78_000484"
     CDS             complement(45867..46904)
                     /locus_tag="VXC78_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV0582627.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(46888..47376)
                     /gene="coaD"
                     /locus_tag="VXC78_000485"
     CDS             complement(46888..47376)
                     /gene="coaD"
                     /locus_tag="VXC78_000485"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV0582628.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(47366..47905)
                     /gene="rsmD"
                     /locus_tag="VXC78_000486"
     CDS             complement(47366..47905)
                     /gene="rsmD"
                     /locus_tag="VXC78_000486"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV0582629.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(47970..48962)
                     /locus_tag="VXC78_000487"
     CDS             complement(47970..48962)
                     /locus_tag="VXC78_000487"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV0582630.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(49074..49757)
                     /locus_tag="VXC78_000488"
     CDS             complement(49074..49757)
                     /locus_tag="VXC78_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV0582631.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(49813..50553)
                     /locus_tag="VXC78_000489"
     CDS             complement(49813..50553)
                     /locus_tag="VXC78_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV0582632.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            50587..50865
                     /locus_tag="VXC78_000490"
     CDS             50587..50865
                     /locus_tag="VXC78_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV0582633.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            50943..51869
                     /gene="yidC"
                     /locus_tag="VXC78_000491"
     CDS             50943..51869
                     /gene="yidC"
                     /locus_tag="VXC78_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0582634.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(51944..52738)
                     /gene="pflA"
                     /locus_tag="VXC78_000492"
     CDS             complement(51944..52738)
                     /gene="pflA"
                     /locus_tag="VXC78_000492"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV0582635.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(52864..54114)
                     /locus_tag="VXC78_000493"
     CDS             complement(52864..54114)
                     /locus_tag="VXC78_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV0582636.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(54181..55008)
                     /gene="purR"
                     /locus_tag="VXC78_000494"
     CDS             complement(54181..55008)
                     /gene="purR"
                     /locus_tag="VXC78_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV0582637.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(55275..56216)
                     /locus_tag="VXC78_000495"
     CDS             complement(55275..56216)
                     /locus_tag="VXC78_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV0582638.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(56206..57462)
                     /locus_tag="VXC78_000496"
     CDS             complement(56206..57462)
                     /locus_tag="VXC78_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV0582639.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(57464..58126)
                     /locus_tag="VXC78_000497"
     CDS             complement(57464..58126)
                     /locus_tag="VXC78_000497"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV0582640.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSGYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(58089..58745)
                     /locus_tag="VXC78_000498"
     CDS             complement(58089..58745)
                     /locus_tag="VXC78_000498"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0582641.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(58756..59634)
                     /gene="rsgA"
                     /locus_tag="VXC78_000499"
     CDS             complement(58756..59634)
                     /gene="rsgA"
                     /locus_tag="VXC78_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV0582642.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(59636..60508)
                     /gene="rsmA"
                     /locus_tag="VXC78_000500"
     CDS             complement(59636..60508)
                     /gene="rsmA"
                     /locus_tag="VXC78_000500"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV0582643.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLMPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(60759..61052)
                     /locus_tag="VXC78_000501"
     CDS             complement(60759..61052)
                     /locus_tag="VXC78_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582644.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(61045..61686)
                     /locus_tag="VXC78_000502"
     CDS             complement(61045..61686)
                     /locus_tag="VXC78_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582645.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(61688..63718)
                     /locus_tag="VXC78_000503"
     CDS             complement(61688..63718)
                     /locus_tag="VXC78_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0582646.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     LGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(63795..64091)
                     /locus_tag="VXC78_000504"
     CDS             complement(63795..64091)
                     /locus_tag="VXC78_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0582647.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(64411..65232)
                     /locus_tag="VXC78_000505"
     CDS             complement(64411..65232)
                     /locus_tag="VXC78_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0582648.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLDTS
                     RTRRPEYAELILEEHMSQIIEKEVYSTNDMLLIRLFFYQMLIRKDLAKFINQIEKLML
                     FLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDYQKKP
                     LVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(65304..65864)
                     /gene="rnmV"
                     /locus_tag="VXC78_000506"
     CDS             complement(65304..65864)
                     /gene="rnmV"
                     /locus_tag="VXC78_000506"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV0582649.1"
                     /translation="MKEKISQVIVVEGRYDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(65864..66637)
                     /locus_tag="VXC78_000507"
     CDS             complement(65864..66637)
                     /locus_tag="VXC78_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV0582650.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(66942..67835)
                     /locus_tag="VXC78_000508"
     CDS             complement(66942..67835)
                     /locus_tag="VXC78_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV0582651.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVGGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATLEY
                     KLETIPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(68119..68253)
                     /gene="rpmH"
                     /locus_tag="VXC78_000509"
     CDS             complement(68119..68253)
                     /gene="rpmH"
                     /locus_tag="VXC78_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV0582652.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        19865 a        15487 c        12552 g        20496 t
ORIGIN      
        1 tataaaaaga agggttagtc attccctcct tttgtgtttt ttataagttg ttttctatag
       61 aaagcttaca tcatcccgcc catcatactt ggatccattg ctggagctgg ggctactggt
      121 tctggtttat tggctacgac tgcttctgtt gtcaaaatca agctggctac agatgctgca
      181 ttttgtaggg ctgaacgact cactttaact ggatcaatga taccttgatc aatcatgtta
      241 acccactcgc cagttgctgc gttgaatcct ataccaagct cagcattttt caaacgatcg
      301 ataacgatag atccttcaaa tcctgcattg tgagcaattt gacgaacggg ttcttccaaa
      361 gcacggagaa caatattacg tcctgttgct tcatctcctg tcaattccaa ggtagcaaca
      421 gctggaatca cattggcaag agctgttcca ccacctgcaa caataccttc ttcaacagct
      481 gcacgagtag cgttgagggc atcttcaatg cggagtttca tttctttcaa ctcagtttca
      541 gttgcggctc cgaccttaat aaccgctaca ccacctgaca atttggccaa gcgttcttgc
      601 aatttttcac ggtcaaattc agaagttgta gtttcgattt gagacttgat aaccgcaaca
      661 cggttagaaa tcgcttcagg atttcctgca ccttctacaa taaccgtgct atctttgtcc
      721 acggtcactc tcgctgcttg accaagagct tcaattgtcg catctttcaa ctcaagacca
      781 aggtcttctg tgataactgt tccgcctgtt aagatggcga tatcttcaag catggctttg
      841 cgacggtcac caaaaccagg tgccttgact gctactacgt tgaaggttcc acgaatcttg
      901 ttcaaaacaa gagttggaag agcctcgcca tccacatcat ccgcaataat caagagtgga
      961 cgattgcttt ggagaatgct ttccaaaagt ggcaagattt cttggatatt ggaaattttc
     1021 ttgtctgtaa tcaaaatgta cggattttca aggtcagcca ccattttttc gctatcagtc
     1081 accatgtact gtgaaaggta accacggtca aactgcattc cttctacgac ttcaagctct
     1141 gtttccatac cacgtgactc ttcgatggtg atgacaccgt ctttgccaac tttttccatt
     1201 gcttcagaga tgtactcacc aactttttca gaacgagaag atacggctgc aacttgagcg
     1261 atagcttctt tattggcaac agggatggcg ttgtttttca aagcttcaac tgctgcggca
     1321 actgctgttt caatcccacg acgaataccg attggatttg cacctgctgt gacgtttttg
     1381 attccttcac ggacgatagc ttgggtcaag actgttgcag tcgtagtccc gtcacctgcg
     1441 atatcattgg ttttagaagc tacttctgat actaacttag cacccatatt ttcaaaatgg
     1501 tcttccaatt cgatttcttt ggcaatggtc acaccgtcat tggtaatcaa gggtgaaccg
     1561 aatgactttt caagaacgac attgcgacct tttggtccca aggttacttt aacagtgtct
     1621 gcaaggatat cgacaccacg aaccatggct gaacgggcat ctgatgaaaa tttaatttct
     1681 tttgacatac ttactttctc cttctattcc tcaatgattg ccaaaatgtt agcttcgcct
     1741 acgatgatgt acttttcatc gccatctttg acatcaagac ctgcgtgggc ttcaactaag
     1801 acacgatctc cagttttaac acttggagca accaagtcac cgttcaaggt acgaacacct
     1861 tgtccagtag ccacaacttg ggctgttttg gttttttctt gggctgaacc tgcgagaaca
     1921 aagcctccaa cagtttgttc tttttcttct acttttaaga ccacacggtc ccctaatggt
     1981 ttcaacatct gatttcctcc ataatctgat ttcctccata atgagataga tattattagc
     2041 actctttata cctgagtgct aattcatagt tctattgtat cacttagtca gaaataatca
     2101 agaaaaaagt ctgactttct caagataaaa agcctgagac caactcagac tttttaattc
     2161 ttaaaatggc aattcttcct cttccaagac caaatctgcc aaatcttggc ctgcattatt
     2221 ttcacgcata gcacgttggg cacgactttc caagagttgg aatcctgtca caaggacttc
     2281 ggttacataa ttcatctgac catttttctc aaagcgacgg gtacgcaatt ctccatcaac
     2341 ggaaatgaga ctacctttgg ttgcgtagct tgccaaagtt tctgctagtc tgccccatag
     2401 aaccatattg acaaaatcag cttcacgttc accgttttgg tctttgtaac gacggttgac
     2461 agcgatagtt gctcgcgcta ctgacttgtc attgttggtt ttgtgcaatt ctggtgtaga
     2521 cgttaaacgt ccaatcaaga taactttatt atacatattt tcttcctcct acttatctat
     2581 tcgtaggaaa tcaaaaaaag ttacagaaat ttgtaacttt tcgagaaaat tttttatttt
     2641 ttatgaacca tgaaacctgt cgcctgttga ttggccataa tggtcatatc tgtaatctga
     2701 acacgacgag gttgactagt cacatagact actgtatctg caatatcctg agcttgcaaa
     2761 gcttctattc cttggtaaac ggacgcagct cgttctttat caccatgaaa acgcactgta
     2821 gaaaaatctg tttcgacaat tccaggctga atggtcgtca ccttgatatc cgttgcgatg
     2881 gtatcaattc gcagtccatc cgaaaaggtc ttaaccgctg ccttggtagc tgagtaaaca
     2941 gcggcaccag cataggcgta gattcctgcg gttgacccca tatttataat atgaccttga
     3001 ttgactttta tcattgctgg caagaaacag cgagtaaccg ccatcagacc tttaacattg
     3061 gtatccaaca tggtcaacat atccaactcc tcatagtctt gatagggagc caagtcaaga
     3121 gccagtccgg cgttgttgac caagatatca atcctcccta tcgtttctag aatatcagag
     3181 caaacagtct tcaccatgac catatccgtc acatctagtg gaaaagtcca gacggtttga
     3241 tttggaaagc ttactgcaaa ctccgacttg aggatttcta atctgtctat ccgtcgtcct
     3301 gttagaacga catcctcacc ctgctccaaa taagcacgcg caatcgcttc accgattcct
     3361 gaggttgctc ccgtaatcac tacatttttt gccatcttat ttccttctat cagatgctga
     3421 caagttccta ggcagtccag tgtttcgctg ggtcgaacgg tgttccgaca acttggtctt
     3481 ctgataattc aagcacccca cgtttttgcg gagcatttgg caaatgcaat tcacgaggac
     3541 tacacatcat cccaaaactc ttttcaccac gaagttcgcc tgggaaaatg aaattccctt
     3601 ttggcatcat ggcaccagga agagccacaa tggttttcaa cccaacacgc gcattaggtg
     3661 ctcctgcaac gatttgcact atcttgtcac ttgcgactgc aacttggcag atgttgaggt
     3721 ggtcactgtc tggatgagct accatctcga caatttcacc aacaacaaac ttaggttcct
     3781 tatcattaac aatttcttct gtaaaacctt ccgcctgtaa ttcttggttc aaacgagcga
     3841 cttgctcatc tgataaaaag acttgaccgc gctctgcaat ttcaaacaag ctcgaaacct
     3901 caaaaatgtt ccaagctact gtttccccat tttctttttt gaggaaaaca cgggctacct
     3961 tgcctttgcg ttccacattc agtttggcat ctccgctatt tttcacgatg accataagga
     4021 catcaccgac atgttctttg ttatacgtaa aaatcattgt ttcctttttc tcctatttca
     4081 atcctgctaa aaaatcgtta atttgctcct tacttttacg gtcgcgattg acaaaacgac
     4141 cgatttcctt gtccttttct agaacaacaa ggctaggaat tccgtaaaca tcccagagtt
     4201 tggccaaatc catatactga tctcggtcca ttcgaataaa ggtgaactct ggattggtct
     4261 cctcaatctc tggtaaggca ggataaatat aacgacaatc gccacaccag tctgccacaa
     4321 aaaggaagac cttcttgccc gctttttcca ctaaagatgc taattcttct aaacttgctg
     4381 gctgtatcat aagacttcct cctcatagac taggtcttca ttttcataga caaaggtata
     4441 atgacggcca tcctcaaaaa tgacgccacc aaccaagctc tccagactgc tttcgtaaac
     4501 ttgaacatag agggtcgcaa tttcccccat gtcggaaaaa tggtctcgca caatctctgt
     4561 caactcttcc tgagtcttca tgagcttacg gtcatctgca acttttttcg tggcaagagc
     4621 aaggcttccg atacctagca gagccaagcc tgccatccac atttttttag ctttcatacc
     4681 attcatttta acacaaaaaa ggcttcagga caaatgagga agcagcagaa aagcaagtaa
     4741 aaagcctctt cctttaagga aaaggacttc ttatactaag accaaactag aaagctagcc
     4801 gcaggctgct caaaacacgg ttttgaggtt gtagataagg cgacgctgac gtggtttgaa
     4861 gagattttca aagagtatta ttcttattgc caggcaccta agttgccaac gtagtaacca
     4921 tcaggtgtgt aggtattgcg aaacatctta cctgatgaag ccagataata ctacttgcca
     4981 ttgtctttga cccaatcatt cgcaatcatg gaaccagaag aacttacata ataccattct
     5041 cccttgtcat aaacccaagt actgactttc atggttcctg agcaattaaa ggcaaaaaaa
     5101 ctgtccaata tcattcgttt tttaaaagca tttgacacta catcatctac gctgtagtac
     5161 atagatacat caaacgtaaa agccaaaata tcgaaaaata tacaactttt aaaggcagca
     5221 tttcattttt taaagtctaa caaccataga actgaaatca gagcaaggca tcaatttcct
     5281 actcttagta cgtctatttt gatggttgaa gtgaagattt ttttatttaa cgtagacaat
     5341 ttccaacttc ccaaaagcca catctccacg gatagtcaag gttttgctgg ttggggctac
     5401 aggagcgtca gccttagctg caccaaagga ggtttctact ttcaaatcta cacgccagtg
     5461 ttgtggaaca tagacggttg catttccgaa ggccacttca atatttaaag ttgcaaaatc
     5521 acctagcatc tctgcattat catagtagat tttagcatcc ccaaaagcga cttccacttg
     5581 gtcatctacg agatcttgat cttgcttata gaaggtcccg ctaccaaaag cgacttcctt
     5641 agccgtgacg actgtttttt tcccattgta ccaccatttt ttttcattcc agaacttact
     5701 tgaatgcgtc agataaccaa caccaagtac caccaagatg ctagcccaaa taagagaatg
     5761 attggtaact ggtaacaagt cataagcgta atttgcaatg atgagcgcca gtaaacctgt
     5821 aaaaactgcc gaagtgagat gacgtctaag gatggactca atggacttat aagcaaaaaa
     5881 aacaatacct agtaaaggcc atattttacc atccaaagaa ggaattccaa aattcccttg
     5941 cagcaagatc caagctgcta aaaccaataa aacaatacca aatgctttct ttttcatgtt
     6001 ttttacctca tgtttcttag attttctttt aggagggatt ggtaatgccg tgagacatga
     6061 acctccttgt gcgtctgata aaaggaaatg gtgcccgttc ctgaaaagga cttgtccact
     6121 gagtaaatct gacggatgtt tgcgatcgtt gacttggaaa ctcgattaaa atagcgaggc
     6181 aagatagact ccaactcata gagcttgagg cgaacctcat aagcttcctt ctggttatga
     6241 gcgtagatct tgctcccttc tgtttcaaag aagagaattt ctgacaggtc tagataatat
     6301 tcacctgtcc ccttgtaaaa agtcaacctc ggagcctttg actcttgcaa gagccgttgc
     6361 aagtctgcaa tttcatctgt caaagtgggg gtcttgatga caatttcagt ctcctctaaa
     6421 ttgccgtcaa tctcaattcg taacttcatc acatctcctt tctgactcta ctatatcaaa
     6481 gctaagttag gaatacaagg gcaaaaaagc aagtggtcaa tttgaagcag taagtggttg
     6541 taggactagc ttaacttaca tgtcagaata ggaagaaaag gaatccccac accaaaccac
     6601 aagcatagcc aaccaagaca tccttgggat aatgaacacc ccctaaaacc ctcaccaacc
     6661 ccagcaaagc tgaaaagatc aagcatacta agccaatagg tagactagca tgcagacagg
     6721 ccacggagat gatagttgcc gaaaagacat ggcgactggg catcgaccgt cccgaactat
     6781 ccttatcaag aaggggacag atatcccaag tttcataagg tctcgggtga ttgattttct
     6841 tacgaaacag ggacaaggcc acaaaacctg atgcaggaat aagcacataa accccaactt
     6901 gctgaccaag tcctagttgc aggtaagtgg tgactagcaa gatcagatag accaggggca
     6961 tggcgactgt catcaaacga ttgaaactgc gtaataggaa taaaagaatt ggacgactag
     7021 ttagtctgga gctgatattt cgataccatt cttgataatt tttcatttat gcttctcata
     7081 cttttctaga acttgttgag atgttttccc cttggcaagc caatccacta gcttgtccaa
     7141 gcgacgtatt ttctgcatca gaggatcatc aatttcctca atacggacac cgcaaatctt
     7201 ccctgtaatt gcaattcgtt cagggacata atatggtgct tgtctaaaaa aatctccgta
     7261 agtaacatcc ctatccagac aagcaagaac atcactcact tcataccctg tcaaccaact
     7321 ggtcacttga tgaactgact ctgcctttcc accctttcgc tcaacttttg caatcaaggc
     7381 taagtagaca gcagcaaatt tcatattgta taatttctga ctcatacttc tctctttcta
     7441 tgtgtactag tataaataag aaaaagaagg ccgtcaagcc ttcttttgat ttattcttct
     7501 gcttcatctt ctgtaaattg actattgtac aagtcagcgt agaagccacc ttgcgccatc
     7561 agttcctcat agttgccttg ctcgatgata tttccatctt tcatgaccaa gatcaagtct
     7621 gcatttcgga tggttgacaa gcggtgggca atgacaaaga atgtgcgtcc ttccatcaaa
     7681 cggtccatgg ctttttggat caattcctct gtccgtgtgt caacagaaga agtcgcctca
     7741 tccaaaatca aaagcggtgc atccttaaga agggcacgag caatagtcaa tagttgtttt
     7801 tgtcctacag acaaggtcac ggtgtcatcc aagatggtat catagccatc tggcaaggtc
     7861 ataataaagt ggtgaattcc cacagcctta ctagcttcca tcattcgttc atcactaatc
     7921 cctatttgat tatagatgag attgtctcga atagttcctt caaagagcca ggtatcctgc
     7981 aagaccattg aaaaggcatc atgcacttct gaacgcgtca tagccttggt atccacacca
     8041 tcaatgtgaa tacttccctt atcaatctca tagaatttca tcaaaagatt gacaatggtt
     8101 gtcttaccag tcccagtcgg cccaacaatg gcaacctttt gaccagcatg agctgtcgca
     8161 gagaagtcat agtcttgaac attgacaccg tccaccagaa tttctcctgc tgacacgtcg
     8221 tagaaacgtg gaatcagatt gaccagagtt gatttaccag aacctgttga cccaataaag
     8281 gccactgttt gaccagtttc tgctttaaag ctaacatgtt caataactgc ctccgaattt
     8341 gccgcatagc ggaaggtcac atccttaaac tcgacctgac ctttgaagtt ttcatcagtc
     8401 agctgcactt gaacagggtt ttggatagaa gaatgcaaat ataaaacttg attaatccgc
     8461 ttagcagaga ccatagttcg gggaagaacg atgaagagtg ctcccatgag aaggaagccc
     8521 atgacaacct acatggcata agacatgaaa acaatcatgt cactaaagag aggcagacgc
     8581 gctatcggag cagcgtcgtt aatcacatag gccccaatcc agtaaatcgc cacactcaaa
     8641 ccacttgaaa tccccatcat gataggattc aaaatagcca taagacggtt gacaaacaaa
     8701 ttcaaacggg tcaattcatc atttactgct gcaaattttt cattttgata atcctctgca
     8761 ttgtaggcac gaacgacacg aatacctgtt aaactctcac gagtgatact gttcagttta
     8821 tctgtcagcc cctgaatcaa ggactgtttt ggaaaggcta gcgtcatcaa aacggtcgtc
     8881 atcaggacgt tgacaatcac tgccacaagt acggcccaga gccagtattc tgaatgacct
     8941 aaaatcttcc caatagccca gatagccata attggaccac acgttaccac ttgcaagccc
     9001 atagtaatca acatttgaac ttgagtaatg tcattggtag tacgcgtcaa gaggctagga
     9061 attgaaaatt tcttaatctc tgtctgcgag taatccaaaa ctcggttaaa aatatcactt
     9121 ctcagcctac tagtataaga agccgccact cgggatgcaa aaaatccaac tgcaactacg
     9181 gacaagaagg caagaaagag cattcccatc atcatgcttg ccggctgcca caactcatct
     9241 aaattagttc cttgactacc tagcaaatcc gtaattttcg agatataggt cggcacttcc
     9301 aactctagat agaccgaaaa gcaagtaaag agaatggcta gtaaaatcat ccccattctt
     9361 ttctactaat tcttttggct aatttcttta ttctctcctc ctattccctt gatatttgcc
     9421 tgtagttgac cgagaacttt ctcaaaaatc agtaattcat cttcatcaat gtcttccatc
     9481 aactgcttgt ctatgcgttc aaaaaaagcc ttaacctgtt gcatctgaga acgtgctttg
     9541 tccgtcagac gaacaaactt agcccgctta tcaacaggac tcgcctccaa ttccaccaaa
     9601 ccattttgca ctatacgctt aaccagatta ctagcaacag acttggtaat attgagttcc
     9661 tgctcgatat ctttaatcaa gaccaagtct tggtttttct cgcgattatc caaaaaacgc
     9721 acaacctgac cttgcggccc acccataaat tcaatgccgc aacgtttggc ttccttttgc
     9781 accatcaggt gaatttgatg accaaaacgc ttaaagacta acatcggttt acccataatc
     9841 tcccccttct aaataaaaat agttctctgg agaataatta aatttctatg agaactattt
     9901 tcttgattaa aaaaatccca agtgattttc tcacttagga tcatgttcta taggttaaat
     9961 taaaacccat ctacgttcgt ataaatcttt tggacgtctt cgtcgtcttc aagaacgctg
    10021 taaagttttt caaaggtttc aaggtcttcg cctgacaatt ccacttctga ctgaggaatc
    10081 atttccaatt cagtcacttg gaattcttca ataccagact cacggagggc aacgatagcc
    10141 ttgtgaaggt cagttggcgc tgtgtaaact gtgattgtac cttcttgtgc ttctacgtca
    10201 tccacatcca catccgcttc gagcaattgc tcaaagactg cgtccgcatc ttcacctcca
    10261 aatacaataa cacctttgtt gtcaaagagg taagaaacag aacctgaagc gcccatgttt
    10321 ccgccgtttt taccaaaggc tgcacggaca ttggctgctg tacggttgac gttagaagtc
    10381 aaagtatcca caattagcat agagccattt ggcccaaaac cttcgtaacg tccttctgta
    10441 aaggtttcgt ctgtgtttcc tttggcttta tcaatcgctt tatcgataat gtgttttggc
    10501 acttgggctt gtttagcacg gtcgataacg aatttcaaag ctgagtttga ttctggatct
    10561 ggatcacctt ttttagctgc tacatagatt tctacaccaa attttgcata tactttagag
    10621 ttggctccat ctttagccgt tttcttggct acgatattgg cccatttacg tcccattagg
    10681 aatctccttt tttcacattt taatctttct tattataaca caagtttttt tgattttcac
    10741 tagaggaaat ggattttatt agcaaatcaa gctaggatag cactttacct gctaagatgg
    10801 tcttgccttt ctatcttttt atcaacagac actcatccac attcaaaaaa caaactagac
    10861 cattatctgc aaatagaaag tttcagccaa gtttgacaaa gtcagctcaa attactgttt
    10921 gaagtttgta gatataagcg acaaaaacaa tcatactgca ccttttgttg acagtctact
    10981 ccagacatat catagttcaa gtaaatactt tgaaatccaa cagttcttat aggcgctatt
    11041 gtattctaag aaatcaatag aagagtttct aagcaaatct ctaatactca ataaaaatca
    11101 aagagcaaac tagaaagcta gcctcaggtt gctcaaaaca ctgttttgag gttgcggata
    11161 gggctgacat ggtttgaaga gattttcgaa gagtataatt tacgtgttcc caagatggag
    11221 aagttagact agtacactgg cacttctaaa ccattgctag caattgattt gttcatattt
    11281 aatttcattt tttccataaa tgggtattag atataaacag caaaatattt ccgatacgtg
    11341 tcgttcttga atttccaatc atctaaaaca agtaaaggat aatcaatccc ctgtatatca
    11401 aggaattggc tacccttttt acttttttac acattctgtt tgatagattc attttaacat
    11461 cacgagcata ctccaatgga aatcgctagg caagagataa actttcagat atccgcagag
    11521 agatcatcgc ctctttttgt cgcaagcatt ctcctctcct agtcattttc taccttatct
    11581 tctacctgcg gatagagagt tgttccccaa atagaaatcg tccgcttacg cactagtggc
    11641 aaatcggttt tttcataaac cgtacgccac cattcccaag caagcccggt acactctcta
    11701 attttgacag agagattacg aacattccct tttaaaggaa tactagtggt aaagtgagcc
    11761 gttaaatcct gcccatttct gtcccaagcc ttaggagtca agacttcctt accttgatga
    11821 tcataggata attcattcca agtaatataa tattgggcaa cataggcacc actatgatcc
    11881 agcagtaaat ctccgtttct gtaagctgta accttagtct caacatagtc tgtactattt
    11941 tgaaaggtcg caactacatt gtcacgtaaa aaagaagttg tataggaaat cggcaagcct
    12001 ggatgatctg ctgtaaagcg actgccttct tgaatcaagt cctctaccat atccaccttg
    12061 cctgttacaa ctcgggcacc cgaacttggg tcgcccccta aaataaccgc cttcacttct
    12121 gtattgtcca aaatctgctt ccactctgtc tgaggagcta ccttgactcc ttttatcaaa
    12181 gcttcaaaag cagcctctac ttcatcactc ttactcgtgg tttccaactt gagatagact
    12241 tggcgcccat aagcaacact cgaaatatag accaaaggac gctctgcaga aattcctctc
    12301 tgttttaaat cctctaccgt tacagtatct tgaaacacat ctcctggatt tttaacagcg
    12361 tctacgctga ctgtataata aatctgctta aaattaacaa tctgaatctg cttttcgcct
    12421 gaatggacag agttaaaatc aatatcaaga gaattccctg tcttttcaaa gtcagaacca
    12481 aacttgacct tgagttgttc catgctgtga gccgtgattt tttcatactg cattctagct
    12541 gggacattat tgacctgacc ataatcttga tgccacttag ccaacaaatc gtttaccgct
    12601 ccgcgaacac ttgaattgct ggggtcttcc acttggagaa agctatcgct acttgccaaa
    12661 ccaggcaaat caatactata agtcatcgga gcacgatcga ccgcaagaag agtgggatta
    12721 ttctctaaca aggtctcatc cactacgaga agtgctccag gatagaggcg actgtcgttg
    12781 gtagctgtta cagaaatatc acttgtattt gtcgacaagc tccgcttctt tctttcgata
    12841 acaacaaact catcgggtag ctgattaccc tctttgatga aacgattttc aatactttct
    12901 ccctgatggg tcaagagttt ctttttatcg taattcatag ctagtataaa gtcatttact
    12961 gctttatttg ccatcttcta cctcctaata agttcctgga ttgagttgca taaactcaga
    13021 cttgttcagc gaaatcagcc gtggttggac taagtaatcc aaaatttcct cgtacaattc
    13081 ttctgagaca ttgcgtcgcc gtctggctag ataagaagtc ggaataaccg tattatccaa
    13141 cataaatacc ttatctaagt caatcaaggt tggtcttgta aaaggattac gagctagatc
    13201 cggctcttct atcataaagt tcttgaccaa acgtctggtc aagagagctg gtttgaaggt
    13261 ctgattttta accaactctt tgtttttagt catgctgttg tcaatacaga tatacatatg
    13321 attcttcaca gccaaatcgc tactaatagt cggaaaaggc aaataaagag ctacaacatc
    13381 tcctctctta atcaagcaag agcaccccct tttctcctaa tgtaacatag acaggattga
    13441 ccaagtcttc tgattgactc agaatttcca aagtttgagt ttggcgcgct gtcaatttag
    13501 tagcatcttg tctcttcaat acaaaatgct tgtcgccaat aaccttgaca atataatcct
    13561 tctccaaagc tgactggtaa atccacatca gatgttgtct gtcctgagaa ctcaagagag
    13621 aaggattttc aagcctcccg atagtctgat aaaaatcaaa aacaggagct aactcctgcc
    13681 aatctgattg gctagttgtc aaggctagaa aaagggcttt gcgagctgat acttcttggt
    13741 tagccttgag agttactttc ccctccaagt tttttagaaa tcgggaaact ccagaaagca
    13801 aatttttctc taactgcgag aaataaaaac ctttcgttcc cagacataag tctttcatgt
    13861 cgctttctct agcaaataag agctcaaaca tttgatagta aaagaaaaat atctggcact
    13921 gggtcgcgct catcttttcc ttatcggctt ctttttttaa ccagagcaag ggcgacaggt
    13981 agctggattg agacatttcc tctacctcct actctttttt aactggagca tctgcactag
    14041 ctgccacttc ttttgactgg atactttccc actggttaat ctcctctgag ataagacctt
    14101 cgcatgtctt gacaaatagg gcaaaagcct tggtctttcc tgcatatttc tccgtttggc
    14161 attgatagag gaatttttct ttctccagga gttgcgcagt tttttggtaa gaaatccaat
    14221 tttcctttgc attatacaaa ttgataatcc cctcacacag caagccgaga ctggataagg
    14281 caaccgaaat caaacggtag cgatcacctg gcataggaat agcacaaaag acagctatga
    14341 ggaaacctgc cacgatttct gttattttta ataccttata gcgcctacga tgttgaacgc
    14401 ttttctttaa aaaatgagct atctgtacgt ctaatcgctc tgtcaggtac atttcttctg
    14461 gcgtcatatt cgtaactcct ttcatttact ttgataatca tagtataaca tatttgaata
    14521 tcaaagtata gtaaaaactg gactataact tattagactt cctacgaaac aaaatatggt
    14581 atagtagttc tatgaatgat gaagcaagta aacaactaac tgatgcacga tttaagctcc
    14641 ttgttggtgt tcagcgtacc acttttgaag agatgttagc tgtattaaaa acagcttatc
    14701 aaaaaagtcg gacaagctgg taaaatcttg gctgacagtg gttatcaagg gcccatgaag
    14761 atatatcctc aagcacaaac tccacgtaaa tccagcaaac tcaagtcgct aatagctgaa
    14821 gataaagcct ataaccatgc gctatctaag gagagaagca aggttgagaa catctttgcc
    14881 aaagtagaaa cgtttaaaat gttttcaaca acctatcgaa atcatcgtaa acgcttcgga
    14941 ttacgaatga atttgattgc tggtattatc aatcatgaac taggattttg gtttcgcagg
    15001 aagtctatta tatatgcaca gacatatgaa atctttttga gatagcagtt atgatatatt
    15061 tatccattca caacatcttc tgtactaata ctacaatatt ggtacatttt gattacacaa
    15121 tcgtttcaaa aaatatgatg gaagcctgag tattttatag taattccctt cctatcaact
    15181 agatcaacca gttgagtgtt gaatgttgaa acaccctagc ctcagcaaag gactatgatc
    15241 agcatttcct agccaatagg acgctccaaa tcacctattc taagtccatc actagcttgg
    15301 tcagtaagat acagactgca aggcgagact gacgtggttg atgagatttt ggaagagtat
    15361 tacaatcata gattcaccag tagacttgac cgcagattta actatagtat attgaaacta
    15421 gaatagtaca cctctacttc taaaacattg ttagaaatcg atttgactgt cctgatcaat
    15481 ttgtcctgtt cttttttcat ttcactatac taaaaaacca cctgaaacaa atcaagtgac
    15541 tagaggataa aaacaaagac tgggcaaaaa gttttgaaaa gcaaaaaacg cataatatca
    15601 ggtcttgaaa aaccttgacg tttgattgtg ggaagattga cttcattttc tcctgaaatt
    15661 gaagtttttt ctagtttcca gatatagacg aattcaatat agccatctcg ctacaattat
    15721 tttaaccatc gagaaaattt ttcagaattt caaaaatttc attttgatcc aatgaaatgt
    15781 catcattttg aagaatagtt gacttcacag gctctaattc tatcacaaag cggtgtatgt
    15841 ctgcttttac cgcactactt gatgttatag ccgataactt ttcatctcct agcaaggaag
    15901 ctgtcaaacg ggtaatgtca ttcaaatgct ttttaatgga cttacttaaa ccttgagcac
    15961 ctgtagcaga gcgttccctc atatccagcc aagctttagc cttaaaaata attaatactc
    16021 aatgaaaatc aaagagcaaa ctaggaagct agctgcaggc tgctcaaaac actgttttga
    16081 ggttgtagat ggaagctgac gtggtttgaa gagattttcg aagagtataa accacaatta
    16141 ctcaataccg aatacccctg aatggtttct ttttcatgca ccaatatatt ataataatct
    16201 tcatccaata ataaggctga taaactagca tcttggtcaa aatgtaaggg aatttctcga
    16261 ccgtccttct ttaatggata ttctggtaag atactaaata gttcaatcat agaaggaaac
    16321 tcaggattag ttgttgtaaa tcgaaaaagc tgcgctttct catctttctg acttccttga
    16381 tactctccca attctaaaaa atgattcaag gtagtataaa attccttatt ttttacttca
    16441 taaatgatga ccatatcata atcttttgtt gtgcgacttt taaatccttg cgaatccaat
    16501 acgatagagg tagcagttcc cccaatcaga acataatagt tctgaaaatc cgcaaacatt
    16561 tcttgaaaaa taactttcgt attagctggc atcatcttct cccagatact gtaatatcat
    16621 attttctagt gcttcactct cttcctctat acgtgggtca tcatcatctt ttaaggtcaa
    16681 ataaagagaa atcggatcta caaattgttt atcatgatta tttttaaaat cattccaaaa
    16741 ctcagataca aaaggacgat atttccatat ctctagcatc tttcctttta aaacatgctg
    16801 agaaagtggc aaggataact gattgaattt tctctgccat atgacatagc tagtattttc
    16861 atccgtttca gctaaaaaag ttgaatgcga caaagcataa gcaccaccat atagaaggtt
    16921 agaaacagat tttatctgct ttatatcgcc atctggcaat aaaatccgtt ttttgatggg
    16981 attaaataaa catgacacgg attttaagaa taattctttc tttgacaccg tatatgtgta
    17041 aagcttattt tgcttgttta accaatataa agctttaaaa gtcctcaaac acctataaat
    17101 tgttgagttt ggaagtccag tgacttgtga aagcaaatca acatctacta ctttttgacc
    17161 ttttgtcaat aaaaaggcaa tccacgttaa ttgttcgcta ggtgttaatt ccttagggac
    17221 ttcagtatca ttcgcattca gtactagtcc caatggaggg aagaagaggt ttcccttaaa
    17281 gtctacaaac ggaactctag cttgaagtaa ttgctttttt tcactgtctg ataacttcga
    17341 aaacaccaaa acaacatcca tattggcttt ttcacccata gtgcgagcct gagtaacaaa
    17401 tgaactcaaa ctcccccttc tcttttcttt aatcaataaa aatgattcct tatgaaaagt
    17461 catttgagta tactcaaacc tttttacaaa actgattggt aaagtcaaag tcagttcctc
    17521 aatactgaca tcaacataaa aggattgaaa aattgacatt atctttttga cattcatgtt
    17581 ttttccttat tctatcattt ttattatatt ttatcattcg gtataataaa atataagttt
    17641 tttgataaaa taaccaaaaa ctactcgcta tcccctctca cattacccta catatcgttt
    17701 gacatgcgac tgatagttca ggaaaacttc aaggagaact tttctctcat ccactatgca
    17761 ggacttacta tttcacttct actcctatag gctcaatttg acacttttct ttttcgaatt
    17821 gctcatatgc ctcctgaata gtgagttcga tttatccaaa tttatttttg tctattttga
    17881 tgaatacttc cacgaagata gtctgaaaat gaatttgcac caattttcct tctcttttta
    17941 agcatattat tccagatatg attgccctct tgttcagtaa taaattacgc tttaaacgct
    18001 tcaatcagta tatctcctgt tgtcatatgt tctaaagaaa attcttctac atatggttta
    18061 acatctctta ggttattact tcctaatatc ccattatgct ttttcgctaa ggaaatagaa
    18121 gccacttctc ccttaccaat aatcttgtta ctatcatgat ttcttgttaa atctctatat
    18181 aatgcgtatt cttcagttcc aatgtctatg ctcacaatct cagctgaacc cttagttacc
    18241 aactggtcta tcctagattt taaatgggga attgtaggta tattgatttc atcatacacc
    18301 tcttgtggaa taacaatttt acccgaatag agcttttcta aaagatgttc agtaccaacc
    18361 cataaaaata ctgaaataca atctgcatca ataaatacac gactagtcaa acgacaactc
    18421 ccccctcttc atctagccca tatacaatat catatctgaa agcatctagt aacagttcct
    18481 catacttccc ttgcgaaatt ctgttatttt ctaaaagttg ttcagttgaa ttaacatatt
    18541 atcctaatat catttacttt ttactttctg acaaaggacg atataaactt gtatcatagc
    18601 ctaatcttga agctgtctct ataacactaa tatccatatt tttaatttct tctgcatcaa
    18661 ggtatccatc attcctcaat ctatataaca taactttatg actgatacca taaaactgac
    18721 ccaattttat aatatcttct acttcaagat gagttctatt ggcattttct ctaatttcct
    18781 caaccatcct atacagtgaa gatgggaaaa ttaaaaaata agaagcaaac tgatccgctt
    18841 ttctttcagt ttcatctcct tcaccaatca agataagact gactgaactc ttcttcacct
    18901 catcataata aagatgatac agttcatgtg ctaaagaaaa tctttacctt cctaatgaca
    18961 tgtctgaatt gactgcaatg agactgaact gagttccttt ataacagact ccgctaatat
    19021 tctttccgag tccataaaat accagcgtca aattttctat cttttgtacc aatttaaaaa
    19081 tatctatcgg cgattcacca tcagctccca acttttttct aagatttgaa gctttattac
    19141 ttaaatccat tcgtgatatt cctttcacct ttttccattt tggcaatcat gctttgattc
    19201 aaagacaaat actcagcaat cttatcttga gtaagatttg aagatattct aagttctttt
    19261 attctttttc caacatcaca tacatttatc acatacattt atcatattca tacacctctc
    19321 ataaaaagaa tagcacactc ttgtcataat tttttaaata aaaaaattat gacaaaacaa
    19381 ggaagcaatt tattgatgct gcttaaaaat ctaaaattga tgagttccta tcaaaaatcg
    19441 tatcttcaac ctcaaaacag tacttaaagc tatccgactc ggtttacatt gtcaaattta
    19501 gattttattt gagcataact ttctagtttg ctttttgatt tttgtttaat atagtagcaa
    19561 aattgaagga aatatctcca caagaaagcg catactatta agctttttca agacctaata
    19621 atatgcgctg ttctgatttg aaagacattc cattattatt ttactgtaat caagccatct
    19681 ggctctactg tgaattctgg cttgtctgcc agtgttccgt ctggtttgag gtagtaccag
    19741 cctgttccgt ccgctgactg gataaaggca tttgatacca tggcgccttc tttagcgtct
    19801 aagtagtacc aagtgtcctt gtacttgacc cagcctgtct tcatggcacc ttcttcgttg
    19861 aaatagtacc acttatcagc gattttcttc cagcctgtag ccatttcgcc tgagttgtcg
    19921 aaccagtacc agttgccgtc tgtgtgcttc ctccagcggt ctgcaagcat atagcctgaa
    19981 ctgtcaaagt agtaccaagt gccattgatt ttctcaaact tgtcttttgg ataagagccg
    20041 tctgaatgta cgtaccagta gccagtgtca ttcttctgcc agcctgtttc aatcgtcaag
    20101 ccgttctcaa tatcatgctt aaactgctca cggctaatgc cccatttagc aagatatgga
    20161 taagggtcaa cgtggtctga gtggttgttt ggttggttat tcgtgcaata ctcgtgcgtt
    20221 ttaattccag ctaaactccc tgtatcaagc gttttcggca aacctgcttc atctgctaga
    20281 ttgcgtaaga gttcgatata aaggcggtag tccgtcatga actcttcttt ggttgaatgg
    20341 ctttcaatca gttcaaccgc tgcataggtc tcagcattcc aaccgccccc aacgtcccag
    20401 gcaccattat caacaggtcc tacctgcatg atgcaaccgt tcccaacaat gtgcgagaaa
    20461 aaacctaatt ctgggtcttt ccgccagtga taatccgctt cattctgtac ggttgaatgc
    20521 ggattcccag ttgagtgtgc gtgtacttgc ctatatggtt gcacgccgac ttgaggcaaa
    20581 tctgttctta atttactcac attaatttcc atattctact ccttatcaat taaaacaact
    20641 cattttttac aatccagaac cagaaactcc tttatttcta ccttacaaag aagacaatct
    20701 tagtcacgat taggcttgta gatagaactt caaaacgcac tattttgaca ctgtaaatag
    20761 gactgacaag gtctgcattc tatctacaat aacaccccag actaaaaagc ttttcaaaag
    20821 tatattttta cagtctctat atgtcctttt cataaatact atactttatt atatcatata
    20881 aaagaagtca aaagtctgtt aaactatttt caacaccaaa ctaaagaaga gaacacaagt
    20941 tttttcgatt ttcactagag gaaatggatt ttattcagta aatccaacta ggattgcact
    21001 ttggttgcca aaattgcctt tccttctttt atcaagggat gacggaatag tgagaagtac
    21061 agttgaactg tcatggcaac ccagataaga ggttcacaaa ggataacacc cttatatcct
    21121 gcccaaggaa taatcaaaac cacaaaaacg atttttccga ttagttcaat aaagctagaa
    21181 actagaggaa ggatcttctg ccccaagccc tgcaagcaat tgcgataaat caacaagagg
    21241 ctcaaaatgg gataaaaggc tgaactgatt tgcagataga gacttccatt ttctatcaag
    21301 taaccatctg tcgaactagc caagaaggaa accaaggctg gactggcaaa aaagaggaaa
    21361 atacaaacaa aaactgccca ggatatactt aaacgactgc cgattcgaag accttgaaca
    21421 atgcggtcag gtcgcttagc tcctagattc tgagaagcaa aggtcgtcat tgatgcagaa
    21481 atagcggtca taggaagaag ggcaaaggtc ataatgcgtc gagctgccgt ctgggcacta
    21541 ataatcactg caccaaatgt attaacagaa gactgtaaaa tcacactgcc gatagataca
    21601 attgaactca tcaagcccat agccaaaccc tgctccaaga gatccgcgta caagcttttg
    21661 tcccatttga aatgtttaaa ctgtggcaag agttctggca cacttttacg aatataataa
    21721 aagcagagaa ccgctgataa accttgcgaa ataatggtag caagtcctgc ggattgaact
    21781 cccagatgca attgcgtaat aaaatagaga tccagaacca cattaaccaa ggcagagaaa
    21841 atcagaaatc ccagggctgc tagactgtca ccaatagacc gcaacaagcc tgcaaaaaga
    21901 ttataagcaa agctgacacc tacacaggtc acaatcatag aaatatattg ataagattga
    21961 ggaagaattt ctgcaggagt atctaagtat tgcaagagag gatacaagcc aagaaagccc
    22021 agcaacataa ctagaatgct caaaagagca cctaaaatcc aggtggctgc tactgcttcc
    22081 ttgattttag tgaaattccg agccccataa taacgagcaa tgacaatccc catgccattg
    22141 ccaacaccaa gtgtaaaacc tacaatcagg tcaaaaatcg ctgtcgtcgc tcctactgca
    22201 gccaaggatt cttgaccaag aaatcgtcca acaatcaaga catcagcagt gttatagagc
    22261 tgttgaaaaa tatttgatag caagattggg aaggcgaagc ttaagagcga gagaagaatc
    22321 ggaccatgta tcaggtccac tgttcgtttt ttattcataa agctattata tcagctttcc
    22381 agaggagcga caagaaacag caaacttata tatagcggaa tgaaataagg acagtcaaat
    22441 cgatttttaa caatgtttta gaagtagatg tgtactattc tagtttcgat ctattatagt
    22501 tggttgagtt tggaatagta cgctgtagct gctaaaacat ttctagaaat taatttgact
    22561 ttcctaataa agttgttcat atcttatttc aagctactat atataatcta aaaacttgaa
    22621 tcaaaaatcg aaaaagtagc ggatttctcc actgctttaa cagcttattc ttcaatttcg
    22681 atttcaagtt catcgcctaa gtcaagcgta acttcttcat tcactgcttc ttctttcttt
    22741 ggctcatctt ttttgttttc agtatcttgt tctgaaactt cttctccatc aatcaagcca
    22801 aatttagaac ggacttgctt atcaatttca tcaaagattt ctgggtgctc tgccaagtat
    22861 ttcttagcat tctcagaacc ttgcccaatt ttttcatctt tgtaagaata ccaagcccct
    22921 gcttttttga taatatccaa atcgcttgca atcttcaaaa gctcaccagt cttagaaatt
    22981 ccttctccgt acataatttc aactacggct tccttaaacg gtggagctac cttatttttt
    23041 acaaccttaa tcttagtttc tttaccgaca ttggtttctt tttgatcacc agttccctta
    23101 atttgtgtat taccacgaac atccaagcgg actgaagcat agaatttcaa agcacgtccg
    23161 cccggtgttg tttctggatt tccaaacatc actccaactt tttcacgcaa ttggttgata
    23221 aaaatggcaa ttgttttggt tttattgata gaggcgccaa gtttacgcat ggcctggctc
    23281 atcatacgag cctgcaaacc aacatggcta tctccgatat ctccatcaat ttccgcacga
    23341 ggaacaaggg cagcaactga gtcgactacg acaagatcaa ctgcacctga gtcaatcaat
    23401 tttcccgcaa tttcaagacc ttgctctcct gagtctggtt gagacaagag caattcgtca
    23461 atattgacac caagggccgc agcataagct ggatcaaggg catgttccgc atcgataaag
    23521 gcagcaatcc caccttcttt ttgcgcttgt gcaactgcat gaagggcaac cgttgtctta
    23581 ccagatgact ctgggccata gatttcgatg atacgtccct taggataacc acctgagcca
    23641 agggcaatgt caagagctaa agaacctgag ctcatcactt gcaccttttg ctccgcacgt
    23701 tcacccaaac gcatgattga tcctttacca aagtctttct caatcaattt aagagcgtca
    23761 ttcaaggcct tttcacgttc tgccccaaat ttttttgaaa tttcttctaa tttttttggt
    23821 tttttcgcca ttctattctc ctacattcta atgatcctca gacctatcta ctattatatc
    23881 aaaagttagt cacttaataa agccttgcga actaggttaa aggcatgcat aaccgcaatg
    23941 tgacgtacat ctgctcggct tctgcctcca atattaacct tgataacctc agttccttga
    24001 tcttgcgcca agcctatgaa gactgtccca actgggtgtc cttctaggct atctggtcct
    24061 gccactccag tcaaactaat tccaaaatca gactgggtct tgcttcgtgc ctgctcagcc
    24121 atcttctgag ctgtaaattc agacaccaca ccatgttctt ccaaattctt ggcaggaata
    24181 tccaacatcc ttgatttttc ctccaagcta taggtcacaa aaccaccctc aaatatactt
    24241 gaaactccag aaaaattcgc cacggtagct tggaaaagac ctgccgtcaa actctctgca
    24301 gccgcgatgg ttttcccttg ccttttcagt tcttctacca caatgctggc taaactagtt
    24361 tcttccccat aaccatagca aaagtctcgt aaagaaattc cttcgaaagt ctggcagtcc
    24421 aagatttgat tttccaagat atccagcgct tgattcgcct cttcttgact gctagccttt
    24481 gttgacagac gtagagtgac ttctcctgtc ttggcataag gggccaaggt aggatcgatc
    24541 tgattatcaa ttaaatcagc caaaatcgta accaactggc tctcgccaat cccaaagaaa
    24601 cgaagaactc gggaatacag cttgctccct gtcatcaact tgggtagaag ttggtttaag
    24661 accatgggtt tcaattcact tggcggacct ggaaggacga cataggtcac tccgtctact
    24721 tctaattttc ctccaacagc cagtcctgtt tcgtttggca gtggaatcgc tccttctaca
    24781 atttgagctt gtctttcgtt atttggtgtt cgggcatagt ctggtcgcag ggtaaaaaag
    24841 atatccaact tctcctgagc ctgaggatca aagactaatg ctttccctaa aaatttagct
    24901 agggtttgtt tggttaggtc gtcctcagtt ggccccaaac cgcctgtcaa aatcaccaga
    24961 ctgctacgtt gactggcaat ctcaagcaaa gacaagagac gaacttcatt gtctcctaca
    25021 gccgtctgaa aatatacatc taccccaatc tcagctagtt tttccgacaa aaactgggca
    25081 ttggtgttga caatctgtcc tgtcaaaatc tctgttccaa cagcaatgat ttctgctttc
    25141 atgtttcctc ctacctatct attcgtattt ttttgaaaaa atcgcaggaa ttttcctacg
    25201 attgattttt tatttgtatc aaaagttaat tatcttcatc accaacaggt gctctgccaa
    25261 ataaatcttc aaataaaacc gcattggttt caagctgagt aacttcttct tgtcccaaag
    25321 aacgtcggag tatattttgc atttccaaca tatgtgctct cgaaacaatc tggtaagaaa
    25381 caccttgaag tatctctcct tcaccctgca actgctgagt ttcaatggtt ttaaatgaat
    25441 ctttatagcc tagcaagtta gggatacttt ttgcagacaa atcaatattg gtctgcatat
    25501 tgtcactcaa agcttttaga atctcttgat aatgaccaac gctatttaaa ctgagagctt
    25561 tttccatgac tttttgaata acttcacgtt gacgtttttg acgaccataa tccccctcag
    25621 gatcttggta acgcattcgt gcatagacta gggcttcttc tcccccaata tgttgctccc
    25681 caacaccgat agaaatagta ttaaattctt cttggtcact gatagaaatt gggaaaccta
    25741 ggatattatt gactgtaata cctcctactg catccactag tttttgcaac cctctcatat
    25801 tgaccatcac atagcgatca atatggatat tcatcatttt ttgaatggtt tctatagcaa
    25861 gctctgctcc accatctgca tatgctgagt tcagtttcgc ttcatgagcc tgaccattcc
    25921 ctgattcaat gcgcgtcaga atatcccgct ctaaactcat cattgttgtt tttttcgttt
    25981 taggattcac tgtcatcaag atcatgctat cacttctacc gacccaagtt tcagttcgtt
    26041 cagcatttcc ggtgtccact cccattaaca gaatggttag aggttcagtc gcttcaataa
    26101 ccttggtttc ttcgccgatt tttttatagg ttttagctaa ggtttctgtc ccttgttgat
    26161 aaatagtata agcaaaaaca cctactccta ctacagttac agaaagtaaa gctagcacca
    26221 ttccaataat ttttttaacc atatttctac taacctatca gtttacccat caagtaaaca
    26281 tcgataaatt tcccttcttc tatatatgcc ccacgctctt ggctaccttc aatgacaaag
    26341 ccatgctttt gataaagatg gactgctgct tgattacgag tttggacagt cagttggaga
    26401 cgacgcagaa tgccacttgc ttgtgcccac tctgtcgctt cttctagcaa caaacttccc
    26461 aagccattat tccaatatct ttttccaatc acaatgaaga gatctccaat atgacggact
    26521 ctcttacgct gatcagctgt aatatttaca ataccagcaa ttttgccatt taagaatgca
    26581 agtaaggtta tctgattgtc cgaactagct tgcttgttga ggaatatttc catctcctca
    26641 ctagtcaaga gaataccatc tccgtctagg ctggtaaagt ctgtctccaa actcacacga
    26701 tttaaaaagg ccactaattc agctgcatct ttgggctctg cttccctaat gagcaattca
    26761 tactccatat tgaagctcct ctaacaattt ctcagcacgc aaaccctttg cctgaaaatt
    26821 taaacggcgt ccatctgctt cttttagaat ttccaattct aaataagcat ctggcaaggc
    26881 atctcctaag agatttcccc actcaataac agtcacgccg ccaccaaaga taaactcatc
    26941 caagtcgata gaatcagcat ctccttcaat acgataaaca tctaggtgat aaagtggaag
    27001 tcgaccttca tactctctca cgatagtata ggtgggactt ttaatcattt gagaaatctg
    27061 taatcctttt gcaagtcctt tagtaaaggt cgttttacct gcacccagtt ctccagttaa
    27121 gattacaaca tcattctttg ctaatagatg gcccaaacgc tcccctaagg cttgcaactc
    27181 ttcttcattt tttgtgtaca tactcttatt ataccaaaaa cttttctttt gtgtctattt
    27241 tcctactaaa cttatcatca taacatccat aaaaaacaga ctttctctaa aagaaaatga
    27301 gcgtaacaat gaccaataca agatctcgga aaatatgacc ataaaaggaa acttccttct
    27361 taaccgaatt tgggacaaga taggctgcaa aaaacaagcc cagtccaata taaatcagaa
    27421 gtgagacaat ggtcattgga tttcttaaga aaagaagtgt tgctaaaata gtcaccaaca
    27481 ctgtcttttt tctgtctagc atagcaagaa aatcgcgcac gtattttttc aagggtaaaa
    27541 aaatcagcaa atctagccca aataggaaaa agaaggatgg caataaaaag tcaactaatt
    27601 cttgctgcag cgtatttttg atgaacaagt tatctgacaa aacaagaaca gctcctaaca
    27661 aattaattaa gagtaacata ctgtaaaaaa gcttcaccga cttcttactg gctaggacac
    27721 tatggacttc ttgcttacgg gtataaagat aatttactcc agcacagatt cctgaaacga
    27781 aaaccatgct tccgatgaaa aaagctgtac tttgtttaaa ggacaagatg cattccttcc
    27841 ataagaaaca gctactcaaa ctgatttgaa ttaaagctaa caaaaataag attctcattg
    27901 atttcatctt ctctctccct tcctaccaat cattatacta ggagaaaaga gagaactgtt
    27961 tctaatcttc tcaaatgtct ctttaagacg ctaaacaaac actagagact aatactcaat
    28021 gaaaatcaaa gatcaaacta ggtagctagc cacaggttgc tcaaaacact gttttgagat
    28081 tgcagataga gctgacgtga tttgaagaga ttttcgaaga atataaattt gaaatcatga
    28141 aaatccgtca aacgggtggt tgttttgtct cgcacctcac ggagcgagac ggactcagag
    28201 tcacataatt ataaggctga tagtattaat ctaactatca gccttacagg ttatttaacg
    28261 tttcagaaaa actataatgt caagattaac taaacagtat ctagttcctt caaataattt
    28321 tctatcttca tcaacattaa aggattgtta taaatcttac ataactctct tgcttctata
    28381 taataatttt tgacttgttc tctgtctaga aatttggctc cagcatttcc tacaagaata
    28441 agtagaggag ccaattggta gcttgtctgt ctttgtttac agagttcaat cgtttcaaga
    28501 gcttcttgga tggcttcatt atatttttcc tttgatacta ggtagtgagc gtagttgtaa
    28561 cgaactctga tgtagccaaa taaaaactct tgatggtcca aattttttgt ctgatacaac
    28621 tctattaaat gagagtagtt tgcctcatat tcttgttcac gacccactaa ggaatagaaa
    28681 ttagatagag tattcaacgc ctttaaataa atcagagtat ttgaagagac ttttaataat
    28741 atattttcca atgaagaaat tgcctcacac ttactgtcat attgatagaa gtcaataata
    28801 gcttgaatcc attcaaggta agttcggtct tctagtgtta gaaaagtact tcgttcaatc
    28861 tctattctat aaatatattc caaatcgtca taatttctat cgtctaatag tcgagcagac
    28921 aattgcttga aattagagag gttagattta atttcaattt gttcattaaa aaaataatct
    28981 aatggtactt caagtcgttg agagagtttg aacaaaaggt ctgcggaggg aatgaaatgc
    29041 cctctctcaa ttttactaat ctggctttgt tcacaaattc cttctgcaag agtttgttgg
    29101 gagagtctca actcttttct tttcaatctg aatttctctg cgagtgtact cattaaagat
    29161 aataaacctt cctatttgct taattgcatt ataaaatttt tagttcaaaa tagcaagtta
    29221 aagaaataaa taattcttta tggtaataaa ctaaaaaaag tcaaaaatta cataaaaatg
    29281 cttgaccgaa taatatatat atattaaaat aaaaacaagg aaaaagaaag gggtttcatt
    29341 gcatgagaaa aaaacgtgga attaaaaaat tagttacatt tgatgcggga tggtaaagaa
    29401 taattgaaga agattctttt atcaatagtt tagtaagctt gttagtttat agagggcagg
    29461 ggtatttctg ccctctgttt tagaataagg aatgcactat gaaaaaatta tttatactca
    29521 tatccaacct gcttgctagt ttgttctttg tttgggtatt taccatttgg actgatacat
    29581 atgtctccca ttattacccc aacgttgttg tacgtgattc ttcccctgaa acaacttttc
    29641 agcatgttgc tacacgcttg gaaaaactag cagaagaaac agatagcttt attgcgattc
    29701 aacaccaaga ttctaactca gaaggtacta cagttttttc ttatacgacc tttggggacg
    29761 gaaagttgcc tgatgggctt caggaaaaaa aactagaaga tgctcaaagt agtagtgttg
    29821 aaacaaacta ttttgtattc gatggacacc tagatattca cttgctaagg gaggagctaa
    29881 gtcaacttgg cttgactaac atgaacctga caattccatc taaactatct acgttaatgg
    29941 ctatctttag taacggattt cagttaatca gtctattgat tttcatctta acctttgtag
    30001 cactgacttt aattagtcaa attagccaat tacggtcgtc gggcattcgc ctcatttcag
    30061 gagagaaacg gtggtccatt ttccttagac cagttggtga ggatttgaaa gggatagctg
    30121 ttggtttcag tttagctggc gtgctcgcca ttcttatgca aaaaattctg tcgcttccaa
    30181 cgcaatccct aatgaccata ggagcaggct tgctcagtta taatctcatc ttgttgtcga
    30241 tctccctgtt tttcgctcaa ctcttcgcag ttgggataaa aaagatacac ctgatgcaga
    30301 ttataaaagg gcaagtgcct gtcagaggaa tcattagttt gattttaatc ggtcaactat
    30361 tagcgattat tattgtaacg ctgggaatag ggagtagctt aaagtattcc caagcctggc
    30421 aacagcatcg gattggacaa gaggcttgga gtcaggaaag gcaactgatt accctatcaa
    30481 tcagccgtga aggaacgagt cctggttttg atgaacaagc tcaaaggaaa ctcagaactt
    30541 ggtatcaatt gatggatctg gctgtttcag aacaaaaggc tttcttatct agacaccagt
    30601 taattgaccg tactttgcaa aatggcatgg cttcctccaa aaacttgata acctctacag
    30661 aatggcacga ttacaacccg aatggcaatg tccttatcgt cacaccgcaa tacttggagc
    30721 gtcaaaacat tcctgtagat acaactattg agcaaaagat gaatcacctt aatgtagggg
    30781 agtttgtctt attgctgcct gaacacctcc gttcagagga agaacattat aaatctgttt
    30841 ttgaagacga cttaaccagt cgcatgtcta gtcaagatga acgacagcaa atgactgcta
    30901 cggtaggtta tttagaatca ggtcaggatc gttttgtgta taatacgacc cctatttctt
    30961 accagcagtt tttgaaagat ccaatcatca ttgttataac accccaatca actggtccac
    31021 agtccatttt gttttggata gacgcagtac agaactacgt tctctttaat caattgtctg
    31081 atgcccagga gcttatccag agacaaggca ttgaaaattg ggtctcagaa atgcaaacag
    31141 gttaccacaa ctacatcaca ttattggata atatccagag ggaacgttgg gtaatgctag
    31201 caggagctgt gcttgggatt gcaacttcaa tcttgttgtt taacactatg aataggctct
    31261 actttgaaga atttagacgt gccattttta tcaaacgcat tgcaggtctc aggttcttag
    31321 aaatccatcg cacttatctc tttgctcaac tgggtgtgtt tttactggga tttgttgcga
    31381 gtgtatttct tcaggtagag ataggagttg ctttcttagt cttgttactc tttactggtc
    31441 tatctctttt acagttacat gtccaaatgc agaaagaaaa caagatgtcc attcttgttt
    31501 tgaagggagg ttaatatgat tgaacttaaa caggtgagta aatcttttgg agaacgagag
    31561 ttattttcga atctttcaat gacatttgag gctggaaaag tctatgcctt aattggttca
    31621 agtggtagcg gaaaaacaac cttgatgaac atgattggga aattagaacc ttatgatggg
    31681 acgatttttt accgaggtaa agacttggcc aattataaat cgagtgattt tttccgtcac
    31741 gaattgggct acctcttcca gaactttggc ttaattgaaa accaaagtat tgaagaaaac
    31801 cttaagctag gtctcattgg tcaaaagttg agtcggtcgg aacagcggtt gaggcagaag
    31861 caggctttag aacaggtcgg cctggcttat cttgacctag ataagcgcat ctttgagtta
    31921 tcgggcggag aatcgcaacg ggttgccttg gcaaaaatta tcttaaagaa tccacccttt
    31981 attctggcag atgagccaac agcttcaata gacccagcaa cctctcagtt gattatggag
    32041 attttgctat ctcttcgaga tgataatagg ctaatcatta tcgcaacaca taatccggca
    32101 atttgggaga tggctgatga agtgttcacg atggatcatc tgaaataaaa atccttgttt
    32161 ttaattgcac gatgagttac tgaaatatta tcatgaatca agaattggag ttaatttaga
    32221 attgtacttt attaatattg aggtaacttt ttcttgataa aggaagaaat aatggagagg
    32281 aagttagaat gaaaaaattc gacaattata ttattgagaa gccttgcgat tctaattcag
    32341 ataaactgca aaaaatctta ataattgaaa gtttggtaga tgatattttg caattttctc
    32401 tcagaatcaa taatagtgta ggagagattt tcctcctaca accgttttaa aagaaaacta
    32461 tctttattcc atgttatttt gaggaagata ttgtgaaagt caaagatgat gataaagttg
    32521 agtggaattt gttagaattt caaaaattta gagcattttt ggcttagtaa tctgtgttga
    32581 aggctcaaaa cctatggtaa aaaagtagct ttgaaaacgt attgcctcca aagatttagt
    32641 taaataatga tttaacacaa aaagaaatta ttgaagttct ggaaagatgt tgtttcagta
    32701 ttgagaaaag gtgggaaaaa cttgcgattt tcacagagaa aggaagaaaa agtatagaaa
    32761 tatagtcaat tgaaacaaga acaggataaa agaacctttt gtgccatatt tttctccttt
    32821 cgctttacaa ttggattgaa cacctttatt gtatcgcgtt tggagttttt ttggtataac
    32881 cttcgacgcg cacccgcata gcgggtgttt tttttgtctc gcacctaacg gagcgagaca
    32941 aactaatagt cacttaatca aaaaacgcac catatcaaaa actaaaaagt ttgatatcat
    33001 gcgtcatgtc ttaaactaat tgactatact ttctattcaa atgagctttt aaccaattga
    33061 ttgagccaat ccactcttaa aaccaaagag caatttctcg cttagctgac tcttctgaat
    33121 ctgaaccatg tacaacattt tggataatct cattttctcc agcagctttt gcaaaatcac
    33181 ctcgaatagt gcctggtaaa gcttcttctg gacgagttgc acccatcatg gtccgccaag
    33241 tttcgattac tttgggacca gaaatgacac ccacaagaac tggacctgaa gtcatgaatt
    33301 cacgaatcgg tgggtaaaaa ctctgaccaa ccaagtcctg atagtgctgg ccaatcaact
    33361 cttctgaaac ctgtgaacga aactccaatt tttcgattgt aaatccacgt tgttcgatgc
    33421 gctttaacac ttcacccact agccctcttt ttacaccatc tggtttgatg ataaagaatg
    33481 tttgttccat acccgtctcc tttgtcagct tctttctttt attttaccac atttcgtgga
    33541 aaaatggaga aagttttcag aagagagaat gagagaaccc gagggttctc tcattctctc
    33601 ttattctact gtttcttcca cagtttcaac ggcagtatcc acaactactt ctgttgtttc
    33661 ttcatttcct tcttcctcta ctggaggatt aaggtattct tcttcgttga cagcatgtgg
    33721 ttcaaggtta cggtaacggg ccataccagt accagctggg atgatcttac cgatgataac
    33781 attttcttta agtccaagga gatggtcttt cttaccacgg atagctgcgt cagtaaggac
    33841 acgagttgtt tcctggaagg aagccgctga caagaaactg tttgtttcaa gtgaggcttt
    33901 ggtaattccc ataaggactg ggcgacctgt cgctggaact ccacctgcga taaggacatc
    33961 tttgttggca tctgtaaagt cattgatatc catgagggta cccatgagaa gatctgtatc
    34021 acctggatcc atgacacgga ctttacggat catttgacga accattacct cgatgtgttt
    34081 gtcaccgatt tctacccctt ggctacggta aactttttgt acttcaccga gaaggtacgt
    34141 ttcaactgac aagacatcac gaactgcaag gagacgtttt ggttggatag aaccttctgt
    34201 cagagcagca ccacgcgcta cttggccccc aacttcgaca cgcatacgag ctgtaaatgg
    34261 aacgacatat tcaccttcgc cagtttcacc cttaacaaag actttcttgg tacgagttga
    34321 tgcatcctct tcgatagcag taacttgtcc tttaacctct gtgataaccg cttccccttt
    34381 aggattgcgg gcttcaaaga tttcttggac acgaggaaga ccctgagtga tatcggtatt
    34441 tgaggcaacc ccacctgtgt ggaaggtacg cattgtaagc tgtgtaccag gttccccgat
    34501 agattgggca gcgattgtac caactgcttc accaacttca accgcatcac cagtcgccaa
    34561 gttgataccg taacagtgac ggcagacacc gtgacgagtg ttacatgtaa atacagaacg
    34621 gatagtcact tcttccacac cagcattgac aatttcacgc gccttgtctt ctgtaatcaa
    34681 ttcatttgga ccaataatca ctgcaccagt ttctggatgt ttaacagttt tcttagtgta
    34741 acgaccgttg agacgctctt cgagagactc gatcatctct tttccttctg cgatagaacg
    34801 gatcaagaga ccacggtcag ttccacagtc gtcctcacgg atgataacgt cttgggcaac
    34861 gtcgaccaaa cgacgagtca agtaacctga gtcggctgtc ttaagggccg tatcggtcat
    34921 acctttacga gcaccgtgag ttgagaagaa catttccaat accgacaaac cttcgcggaa
    34981 gtttgaaagg attggcaatt ccatgatacg tccattcgga gcagccatca gaccacgcat
    35041 accggcaagc tgtgagaagt ttgagatgtt accacgggct ccagagtcca tcatcataac
    35101 gattgggttc ttaggatctt gattagcaat caagcgtttc tcaagttttt cacgggcagc
    35161 acgccattca gctgtaacag cattgtaacg ctcgtcgtct gtgatcatac cacgacggaa
    35221 ttgtttggtg atttgttcga cacgtttgtg tgattcttca atgatttcag ccttgtcatc
    35281 aacgactggg atatcggcaa tacccactgt caatcctgca agagttgagt ggtggtaacc
    35341 gaggttcttc atgcggtcaa gtagggcaga agtttctgtc gtacggaaac gtttgaagat
    35401 ttcagcgatg atatttccga ggtttttctt cttgaatgga gggttgagct caagattgct
    35461 gatagcttcc ttgatatctc caccaagtgg caagaagtat ttagctggaa caccttctgt
    35521 caagttggca ttgtttggtt cttgcaagta tggtagcccc tctggcatga tatcgttgaa
    35581 gagaatttta ccaactgttg taagcaagac cttatgtctt tgctcttctg tccaaggctt
    35641 gttgaggctg tctgttgcga taccaacacg tgagtggagg tgaacataac cattgcggta
    35701 agccataacc gcttcgtcac ggtctttgaa gaccattcct tcaccttcgc gaccagcttc
    35761 ttccatggtc aagtagtagt tacccaaaac catgtcctga gatggagtaa ctaccggttt
    35821 cccatctttc gggttcaaga tgtgctcagc agctagcatg aggatacgag cttctgcttg
    35881 tgcttcttct gaaagtggta cgtggatggc catttggtcc ccgtcaaagt cagcattgta
    35941 ggcttcacag acaagtgggt gcaagcgaag agccttacca tcaatcaaga ctggctcgaa
    36001 ggcttggata cccaaacggt gaagggtcgg tgcgcggttc aaaagcactg ggtgttcttt
    36061 aatcacttct tcaaggatat cccagatacg ctcatctccg cgttccacca agcgtttagc
    36121 tgctttgacg ttttgcacga tatcacgggc aacgatttca cgcatgacaa atggtttaaa
    36181 gagttcaatc gccatttcac gtggcacacc acattggtac atcttaagag ttggaccaac
    36241 ggcgataact gaacgtcctg agaagtcaac acgtttaccg agcaagtttt gacggaaacg
    36301 tccttgttta cctttaagca tgtggctcaa tgatttcaat ggacggctac ctggtcctgt
    36361 gattggacga ccacgacgac cattgtcaat caaagcgtca actgcttctt gaagcatacg
    36421 tttctcattt tgaacgatga tacctggtgc atttaactca agcaaacgag ccaaacggtt
    36481 gttacgattg ataacacggc ggtaaaggtc attcaagtca gatgaggcaa aacggccacc
    36541 atccaactgc aacattggac gaagatctgg tgggataacc ggaaggatgt taagaatcat
    36601 ccattcaggt ttgtttccag acttgtaaaa ggcatccaaa acatccaaac gacggatggc
    36661 tttgacacgt ttttgtccag tagctgtttt caattcttct ttgagttcag caatttcttt
    36721 ttcaagatct acttgcttca aaaggtcttg gatggcttcc gcacccatct tggcaacaaa
    36781 tgaaccataa ccatattcgc gcaagcgctc tcggtattcg cgctctgtca tgatagactt
    36841 gtgctcaagt ggtgtatcct taggatcaat caccacataa gccgcaaagt agataacttc
    36901 ctcgagggca cgagggctca tatcaagggt caagcccata cggcttggaa tccccttgaa
    36961 gtaccagatg tgagatacag gagctttcaa ttcgatatgt cccatacgct cacgacgaac
    37021 tttcgtacgc gttacttcaa ccccacagcg gtcacaaaca attcctctgt aacgaatgcg
    37081 tttgtactta ccacaagcac attcccagtc ttttgtagga ccaaagatca cttcatcaaa
    37141 gagtccttca cgttctggtt tcaaggtacg ataattgatt gtttcaggtt ttttgacttc
    37201 tccataagac catgaacgga ctttacttgg agaagctagg gtgatttgca tacttttaaa
    37261 acgatttaca tcaaccacta tttcttccct ttctattcta agtgaactgc ttattcttgt
    37321 tcagcagctt cttctgttgc ttccgctttt gttgctttct cagcttcttc agcttcaaag
    37381 gctgctttag cctcttgggc tgctttttcg cgggcttttt caaggtcatc tacgtggatg
    37441 acatcttcgt ccattccttc atccaagtcg cgaagttcca cttcttggtc atcttcgtct
    37501 aggacacgca tgtcaagacc aagagattgc aattctttaa caagaactcg gaaggattct
    37561 ggaacacctg gttttggaat tggtttgcct tttgtaatag cttcataggc tttcaaacgt
    37621 ccgttgatat cgtcagactt gtaagtcaag atttcttgaa ggacatttga cgcaccgtag
    37681 gcttcaagag cccaaacctc catctcaccg aaacgttgtc caccaaactg agctttacct
    37741 ccgagtggtt gttgggtaac agttgagtaa ggtccgactg aacgcgcgtg caatttatcg
    37801 tcaaccatgt ggtggagttt gatcatgtac atgactccaa cagaaacacg gttatcaaat
    37861 ggttcaccag tacgtccatc gtaaaggatc gttttggcat cgctatccat acctgcttct
    37921 ttaacagttg accaaagatc ttcagaactt gctccatcaa agactggtgt cgcaatgtga
    37981 ataccaagag tacgagctgc cataccaagg tgaagctcca taacctgacc gatattcata
    38041 cgtgatggca ccccaagtgg gttcaacatg atgtcgactg gagttccgtc tggaaggtaa
    38101 ggcatgtctt ctacaggaac gatacgagag acaacccctt tgtttccgtg acgtccggcc
    38161 attttatctc cgaccttaat cttacgtttt tgagcgatgt aaacacgaac caacatgtta
    38221 acacctgatt gcaactcatc tccatttaca cgtgtaaaga tcttaacatc acgaacgaca
    38281 ccatcggcac cgtgtggtac acgaagagaa gtatcacgca cttcacgaga cttgtctcca
    38341 aagatagcgt gcaagagacg ttcttcagct gaaagatctt tctcaccctt aggtgttact
    38401 ttccctacaa gaatatcacc ttctttaacc tcagcaccaa tacggataat ccccatttcg
    38461 tcaaggtctt tgagggcatc ttcaccaacg tttggaattt cgcgagtgat ttcttcaggc
    38521 ccaagctttg tatcgcgcgt ttctgattcg tattcttcaa ggtgaacaga tgtgtagaca
    38581 tcgtccttca ccaagcgttc gctcatgata acggcatcct cgaagttgta gccttcccaa
    38641 gtcatgtagg caacgattgg gttttgtcca agcgccattt ctccattttc catagaaggt
    38701 ccgtcagcga tgaaatcgcc tttttcaacg acatcaccaa cttttacgag agtgcgttgg
    38761 ttgtaagcag tacctgagtt tgaacgacgg aatttttgga tgtggtaaac atccaatgaa
    38821 ccatcttcac gacgaacttc taccttgtca gcatctgcgt aagtaacttt accatcatac
    38881 tgagcaatca cagccgcacc agaatcgtgg gctgcttggt attccatacc agtaccaacg
    38941 taaggtgcct gaggattaat caatggcaca gcctgacgtt gcatattggc tcccatgagg
    39001 gcacggttgg agtcatcgtt ttccaagaaa ggaatacatg ctgtcgcaac ggcaactacc
    39061 tgttttggtg aaacgtccat gtagtcaaca atattagctg gatactcttg gttgacccct
    39121 tggtgacgtc ccatgacaat cttctcagca aaggttccat cttcattcag acgagagtta
    39181 gcctgagcta cagtatattc atcttcttca tcagctgtca accaaacaat ttcgttcgtg
    39241 acaacacctg tttcacggtc aaccttacgg tatggtgttt gaacaaaacc atatttgttc
    39301 aagtgtccgt aagatgacaa gttattgatc aaaccgatgt taggtccttc aggtgtctcg
    39361 attggacaca tacgaccata gtgagtgtag tgcacgtcac gcacttcata tccggcacgg
    39421 tcacgagtca aaccaccagg tcctaaggct gacaaacggc gtttgtgaga caactcagaa
    39481 agcgggttgt gttggtccat gaactgtgac aactgtgatg aaccaaagaa ttctttaact
    39541 gcagctgtta caggacgaat attgataatt tgttgtggtg tcaagacttc attgtcctga
    39601 acagacatac gttcacggac attacgttcc atacgagaaa gtcccaaacg tacttggttg
    39661 gcaagcaatt caccaaccgc acggatacga cgatttccaa ggtggtcgat atcatctaca
    39721 cggccaagtc cttcagccaa gttgaggaag tagctcatct cagcaaggat atctgcagga
    39781 gtcaccgtac gaaccttgtc atctgggtta gcattaccaa tgatcgttac gacgcgatct
    39841 ggatcagttg gagcaataac cttgaatttt tgaagaacaa caggctcagt cacaacggct
    39901 gcatcgtttg ggatgtagac aatcttgttc aagtcgccat ccaaatggct ttcaatgctt
    39961 tcaatcacgc tacgagtcat aatcgtacca gcttctacca agatttctcc agtttcaggg
    40021 tctaccaatg gctctgcaat ggtttggttg agcaaacgtg ttttaacatt gagtttttta
    40081 ttgattttgt aacgaccaac tgctgccaag tcataacgac gtgggtcaaa gaagcgagct
    40141 acaagcaagc tacgtgagct ttcagccgtc ttaggctcac ctggacgaag gcgttcgtaa
    40201 atttctttca aggcttcgtc tgtacgagag tccattggat tcttgtggat atctttttca
    40261 acagtgttgc gaaccaattc gctgtcacca aagatatcaa agatttcatc atcacctgag
    40321 aaaccaagag cacgaaccaa ggttgtaaat ggaatcttac gagtacggtc gatacgagtg
    40381 taggtgatat cttttgagtc gctttcaagt tccaaccaag ctccacggtt agggataaca
    40441 gttgaaccat agcccacctt accatttttg tctactttgt cgttaaagta aacacctggt
    40501 gagcggacca actgagaaac gataatacgt tcaccaccat tgatgatgaa agtacccatt
    40561 tctgtcatga ttgggaaatc accaaagaaa acttcttggg tcttgatttc gcctgtttct
    40621 ttattgatca aacggaaggt tacaaaaatt ggtgctgagt agctagcatc gtggatacga
    40681 gcttcttcta gcgtgtattt tggttccttg atttcatatc caacaaattc caactccatt
    40741 gtgtctgtga agtttgaaat tggcaataca tcttcaaaca cttccttaag accgtggtct
    40801 aggaaagctt tgaatgagtc agtttgaatt tcaatcaaat ttggtaagtc aagaacttct
    40861 ttgattcttg aaaaactacg acgggtacga tgtttcccgt attgaacgtc atgtcctgcc
    40921 aagatgattc tcctttgtaa ataagttcca agccttgtca atcaggcttt tctaatcgtc
    40981 atatggttgt aaacccctta tcaccgtgtc ctcttgacga attttcagaa tctttaagcc
    41041 tctgttacaa atgctcataa tcttgaaaaa aagcacaaaa agagcagcta aatctgactt
    41101 tttcagaaga tttaactgct gtgagccttg tctggacaat atttcagaca aaacctacga
    41161 caaatgatta cccatattat accctattta gctagatttt tcaaggggtt tcagtaggtt
    41221 tttggtaaat tttttcccat agaaaacttg gcatcacatt cgaatcacgc tatggtacaa
    41281 aaaactgaaa aaactattga ctggaaatca ttttcaaggt ataataataa acgttaaggc
    41341 ggtatagcca agtggtaagg cacggctctg caaaagcttg atcgtcggtt caaatccgtc
    41401 taccgccttc tataacttga tttatcaggt ttcaaatgaa cagaaagccc aatttgaagg
    41461 gcttttctta ttttccctcg aataaatacg tataacttta aaaacttttg gagcgagttt
    41521 gtggcagagt tctttccatg gcataattcc cttttgaaat caattgaaaa aagcttcgtc
    41581 acgcctggtg acaaaagcct ctagtttatt ctgtttcttc ttctatttcg acttctgtga
    41641 tttggacttt taccttggta acacgtccat tcttcacttt atcattggtt aagataaact
    41701 gtttgttttg gctgaccaat tcatagctga gtttctcagt cgttggaata gttcccactc
    41761 ctgtcaaata ataaccagcg atggtatcaa cgtcatcact ttccagttca acatcaaagt
    41821 aattattgaa atcattgagg gtcatagttc cttgaacaat gtaggtatcc tcgccaatct
    41881 gatgaacatc tattgctgct ttgtccgttt catcatcaat ttcaccaaca atttcctcta
    41941 agaggtcttc caaagtcacc aaaccagcca taccaccgta ttcatccagc aagattgcca
    42001 tttgtctttg ggtatttcgc agttctttta gcaagtcatc cacaaaaata gtttcaggta
    42061 caaaaagtgg atcttgtaaa attctcttcc aaacaatatt gtcaaaaccg tccacaaagc
    42121 ctgccttaag gagactcttg gtgtgaatga ttccaattac attgtcctta tccccatcat
    42181 aaaccgggat acgagaataa ttttgtttta aaatactttg gataatggct tgactatcat
    42241 cctgaatatc caccataaag gcatccgttc gaggcaccat aacctctcgt gccatcagtt
    42301 catcgagcga aaagacacct tgtagcatct caatctcatc agcatccaat gtttcttcac
    42361 tatttgtcag catataggca atttcatcac gggtcatctt ttcatccgca tcatcgaatg
    42421 acataggagt caaatggctc aagaaattgg tcgaagcagc taaaagccaa acaaaaggac
    42481 tgactagttt tccgatccca atgataatcg gcgctgtacg aattgccaag gcatccttta
    42541 gattaagagc gattctctta ggatataatt ccccaaaaac gatggaaata taggtcaaaa
    42601 atgccaagga tagaaaagtt gccacggctt gtgctgtttc gccattccca agccaagagg
    42661 caatcacacg tcctagagta tcagttaaac tcgcccctga taagattgta atcagggtga
    42721 ttcctacctg aatggttgat aaaaagtggt taggattttc tagtaccttc agcaggcgga
    42781 tgtagcgtct gtctccttct tccgcctttt gttcaactcg ggcacgatta agagaaacca
    42841 tggccatttc tgtggctgag aaaaaggcat ttaataccgt caagataaac aataaaacaa
    42901 attgtagcaa caaattctga ctacttgggt cttccatagt tcttctccta aaatagtatc
    42961 ttatccttta ttatatcaca aaatttaatc caatacatat tatttttttc ttagcgtaac
    43021 ttccatctct ctcccaaaac tggaagttag tctaagacgg atttccactg atttcacgcg
    43081 tttttctcat actaaaagct aggttgtggg aaactggaag ttagttttag aagttactat
    43141 tttttcttag cacctattct agccctgctt aaactagtaa aaagaactcc tacatccata
    43201 agtgacatag gagtttaggc ttatctttta ctgagttaca gttacttctc cagttcggta
    43261 atccagttga agtccctttt gaacattggg aactagaaca ttgaattcca attctccatc
    43321 cgaagacttg gcttcaatct gtgaagctga gggaactaaa tcctcgtttg aagcgtagta
    43381 aagggttaca cggtaacgga cacgcttgtt ttggtccaag gctttacgca ccttgctttc
    43441 atagtagttt tgaccagtcg aatactcggc ttgtgcctga tttgcccagg ctgtctgaac
    43501 agcaatgttt ttaggattgc ttgttgaggc atcaaaacca tccaaaccac cgattaaggc
    43561 atagcctaac aaatgacctc tatcgactgc atgggtataa gagcccttta gattcttgac
    43621 ctgatgccaa cctggaggag tccaagaagt tgaaccattc ccagtttctt tacgattctt
    43681 gtactgacga gtggccttag acaagagggc attagctacg gttggaacag tttccttgcc
    43741 cactgtcttt gttttattgt cagcgtaggg cttacttgaa accttggcat ctagatttgt
    43801 tttattacca ttgacgataa aagcacctga gccattccac tccagactcc cctttatttg
    43861 actcttgact gcgtctgtta agacactctc tgccaatgct tgactaggag cttcagacgc
    43921 ttgttttttc tgactaagat tggttttggg actattaggt gccgactgca tctgcttgat
    43981 ataatagctc cctgtagaca aaagcaataa cactagcagt ccgattagtg tctgtcttgt
    44041 ttttttgttc atatttctcc ttatctttag aaaaaggctg gttctccagc ctaatttcct
    44101 gtaaatttat gaatcaattc ctgccatttt gctggagaca ggatagccca tggatcttga
    44161 cccttgccca agattccata acctaccatt agaccgattc ctagagccag agtacctaaa
    44221 atcagtacta tgatgactaa aagtaaacga ttgattacgt agcttgattt cttattcatc
    44281 ttcatcgctt gcctcaatcc gctgaatctt agcacctagc tgcgccaact tctcatggaa
    44341 accgtagtaa cctctatcca agtgaaccaa tttaccgacc acagtttctc cctgtgctac
    44401 caaacctgtc aaaatcaagg ctgcactggc acgaaggtca gttgaaagaa cttctgctcc
    44461 ctgcaaaggc tgtccaccaa caatacgagc tgtatcacgg ataatctcag aatgcaagcc
    44521 catgcggcgc atctcttcta ggtgttggaa acgattttcg aaaactgtct ccaccatggt
    44581 tgattcgcct tttgcaactg tcatcaaggc tgtaaattga gcctgcatat ctgttggaaa
    44641 tcctgggtgg ggcaaggttt tcacatgaac agcttttaga ttttctagtt gagaacgaac
    44701 acgaattcct tcgtcttctt caattacttc aacacccatt tcaagtaact tggcaatcaa
    44761 gggacggttg tgctcccaga cagcgtctcg aatcaagaca tcaccaccag tcatggcagc
    44821 agctaccata aaggttcctg cttcgatacg gtcttggact acattgtgag tcgtaccatg
    44881 aagtttctca acaccagtaa tggttatagt ctctgtacca gcacctttga ccttggctcc
    44941 catttcatta aggagaatgg ctaagtcaac aatctcaggc tcacgcgcag cattctcaat
    45001 cactgtcacc ccatcagcca gagtcgctgc catcatcaag ttctgcgttg caccaacact
    45061 tggaaagtcc atatagatat gagcgccatg caagcgttct gccttggctt cgatgtaacc
    45121 agctgtctga ctaatcttaa cccccatagc ttccagacct ttcaaatgaa gatcaatagg
    45181 acggctacca atcgtacaac cacctggcat ggataccttg gcatgaccca cacgggcaag
    45241 gattggccct aatacaacga tggaggcgcg catcttgctg acatacttgt aaggggcttc
    45301 ctcagtgatg tcgccagtag catccacctt gacaagatga gcttcctcat caaagtcaac
    45361 cttggcattc aaaccaccaa ctacctgatt cataataaag acatccgaca aaatcggaac
    45421 attctgcaag acggtctttc cttcacttgc tagaatagtc gctgccaaca agggtaagac
    45481 tgcatttttt gctccctcga tcgtcacgct tcctaccaga cgattatcgc caccttgaac
    45541 cacaatttta tccatactcg tttcctttac tcttgatttt ataataatcc tctaagcgct
    45601 tcttgccaca aatgatacag gctaataaag aaagaactca ggatgtagcc tatgacaatg
    45661 ctaaaaaagg ctactaataa acgaactttt cttgtattat catctgtcac ttttaaaacc
    45721 ttctcccatc taacaagatc ctttaaaagg taaaaactca cataaataaa gagcatatga
    45781 ctacttagag tgaataataa ttgaaccatt tgactattat accatcttct ctgtttgtgc
    45841 gctagtttgg aaacttcact caaaaattag ggattgtttt tcaagtaatc aatcgcatct
    45901 tgtagggttt taacgggcac gattttcata tccgtcttga ttgttttagc cgcttctagg
    45961 gctgtttggt agttgttttt cgcgtccaga tgcgcctttt gttcttcttc gctaacaggg
    46021 ttatcaggag caaagaaaat agcagcacct gccctagccg aagctacaac cttcttatca
    46081 atacctccaa tgtctcccac attaccatcg cggtcaatgg tacctgtacc ggcaacaata
    46141 cgaccattac gaagatctgg gtgagctatt tgagtataga tagctagact aaacatgaga
    46201 ccagcacttg ggccgccaat accagctgtt gaaaagctaa ttgggacatt gctgattacc
    46261 tctgtacggt caatcaagcc gattccaatt ccatttttgc cattttccaa ggtgataatc
    46321 tttccttctg cagacttggt ttgcccatcc tcttcatagg tgaccttgac ggaatcccct
    46381 aatttttgag aactgacgta atcaatcaag tctttggaac tatcaaaggt ctgatcattg
    46441 actgctgtga ctgtatcaga gatattgaga atccctttaa aggttgaatt atccgtcaca
    46501 ttcaaaacat aaactccaaa gtacttgagt tcgatatcct taccagctgt ttttagtcct
    46561 tgatacttgg ccatattttg cgatgtttgc atgtagaatt gattgattcg cataaattca
    46621 acatcggaag aaccacctgt agtctcctga gcactacgaa tatctgtaaa aggtgtcaac
    46681 caagcataaa tcatatgagc taaagtggca tgttgaacac caaccgtaac gaattgatag
    46741 gcaccagctt ccttatcttc tgtgtcattt actttaagga cttggcgaat atcttccgaa
    46801 ccacctggaa cctctatata ataaggcaag ggcactacaa atgccaagaa agtcacaatc
    46861 aaggccgcaa tgacgtataa gggccatcta atcttttttt tcatttctta tttcctccaa
    46921 aatactctcg ggaacatggc aggcaatatc ctgaccaaac ttcaaaagct ctcgaacacc
    46981 tgatgaactg atatagagat gttcaggccg gctatgtaaa taaatagtct ctatatcaga
    47041 agacagctga tgattgtagt aatcaaaact agcttcatat tgcaaatccg ccgcattcct
    47101 caacccccgt actaggaaag tagcccccag tctttttgca acatcgacca ccaattcatc
    47161 atgagaagcc acgacttcaa cattttccaa atgtcccaaa gccttttcta gcccccgttt
    47221 acgattttca agagggagaa atccttgttt gtggggatta aaaaaaatac ccacataaag
    47281 cttatcaaaa agtctgctcg cccgttcaat gatatccaga tgcccatttg tcatcggatc
    47341 aaatgagcct gtgaataagc caatcttatc tgacatagac tgtcacctta ctaattccat
    47401 aaatcttttc cttccagata cccagacagg caatctcttc tggaagttca acggccttat
    47461 ccgtctcgca cacaaccata acatcttcag aaaaaagctc tctcttagcc attttttcaa
    47521 tatctgctac gatttgttcc ttggcatagg gagggtctaa gaaaacgagg tcaaattccc
    47581 cagatacctg ttccaatgcc ctctctgcat ccatcttgag gagttgaaat tttccaactt
    47641 ccttggtcat ctggatattt tcagccacga tggtctgagc cttacggtct cgctccacca
    47701 aaacagcact ggacatgcca cgcgatactg cttcgataga taaaccacca ctacctgcat
    47761 aaaggtccaa gactcgtccc ccttcaaagt agggaccaat catgttaaaa atggctcccc
    47821 taaccttatc cgaagtaggt cttgttgtct tgccttctag tgtcttgagg ggacgtcccc
    47881 catagattcc tgatacgatt ttcatactgt ttattatacc aaattataga caaaaagaga
    47941 aagaaaaccg aaccttgcgg ttcgattctc tacaaaatat tttcgtaagt atcgcggact
    48001 tcttgaggcc aaacacttgt ttgcacttct ccgatgtgtc tcttgcgaag taggaacatg
    48061 gccatacgag attgtccaat tcctccaccg attgtcaatg ggaataggcc attcaacaaa
    48121 gacttgtgcc attccaattc caagcggtct tcatcacctg taatttccac ctgacgtcta
    48181 agagtttctt catctacacg aattcccata gaagacaact caaaggctcc acctaaagac
    48241 tcattccaga caagaatatc accatttaga cccttgtagc cattctcaga ctcgcttgtc
    48301 cagtcatcat agtctggtgc acgtccatcg tgcggtttac catctggcaa ctcgccaccg
    48361 ataccaatca aaaagacggc tccaaattct ttacaaatcg cattttcacg ttctttaggt
    48421 gtcaagtctg ggtagcgttc taccaattct tctgtatgga taaaggtgat ttgttttggc
    48481 aagatagact cgatgtcata gcgggcttca acagctagct cagtcaggcg aatagcctta
    48541 taaatcttct caactgtttc ttttagataa acgatgttac gcttaccatt tgggataacc
    48601 ttctcccaat cccactggtc aacataaaca gagtgggttg catccaagga atcctcatct
    48661 ggacgaaggg ctttcatgtg gacaaagaga ccctctcctt caccaaagcc aaaacgagcc
    48721 aaggtgtggc gtttccattt agcaagtgag tgcaccactt cataagtagc atcagggatt
    48781 tggagaacct tgaccgatac tggattttcc acaccagaca ggttgtcctg cattccgtca
    48841 ccgaccttac tcaagatagg accttgaact tcgacaactt ctagcttatc tttcaaatac
    48901 tgggtaaaag tgtttttgac aaaggaaatt tcttcttgtt gatggataaa acttttcttc
    48961 atagacaact cctcaaaaat ttaataaacg tattatacac ctatttccaa gaaaagaaaa
    49021 gagaaaattt aaaaaaaatc agtgtcactc aaaacactga tttcatagac cttttagtca
    49081 ttgcgaccaa agatacgtag aatacttagg aaaagattga taaaatcaag atagatgctg
    49141 agagccattg acaccaccca gcctgtcgct acacgacctt gtgattgttc ataggcgagg
    49201 cgaatctttt ggttatccca agcaatcaac cctgaaaaaa ccaaaaccat ggctacgcta
    49261 atcatataat caaagaagcc actagccaag aaaatattga ctaccatagc aatcagtaaa
    49321 ccaatgagag ctgccatcat tgctcgacca atcccactca agtctttctt ggtaaaaata
    49381 ccaactgccg ccatgacaaa gaagagaagg gcgctcgata caaaggcaga taaaactgta
    49441 cccggagtat agaaagccac cacaaaacta agggtaaagc cgtttaaaac ggagtaaagt
    49501 aaaaatactg gaagagcagc tggactattt cttgaagcca tgctactggc aacgaaaacc
    49561 aaagccaact ccgcaaaagt agcaatggtc aaccagagac gcccctgcat caaaaagtaa
    49621 accaactgag actgaaagac cgtcaacata aggcctgata ccaaagcaga tagtccgatt
    49681 cccagaccaa caaaggcata aaccttagcg taaaattgat tgagacctgc acggtcatgt
    49741 ataatagtgt gattcatcca tttctccttt tctgtgaaca tctttccttg attataacaa
    49801 aaaaagttaa aattagctta aatggaagat taaaataccg gctgcaaccg caacattcaa
    49861 actctcggcc tgccccttca tgctaatatg gaccaactgg tctgcacttt cagccataag
    49921 gggactaatt ccttgaccct catttcccat aactagtaca aaattttcta tagaaggcag
    49981 ttctctgtaa tcaacagaat ctttagatag ggttgttgct agcactggga tagctacctt
    50041 tttagtttcg tcaagaagcg cttgactagt catccggtaa atgggcagat ggaaatgact
    50101 accttgcatg gaacgtaggg ttttgagact gtagatgtct gccgacttat ctgaaacaat
    50161 cactcctgta aaacctgctg catccgcagt tcgaatgata gttcctacat taccaggatc
    50221 ttgcacatct tccaaaaaca agaacttgcc ctgactcaaa tcagcttgtc ctacttcttc
    50281 tttttgaacc acggcaacaa ttccctgtgg agtctgagaa tccgccaaat ctagcaaaat
    50341 atcctctgac acccagacag tttgcgaaaa agtagctaac tgatctcgat aattttctag
    50401 ggcaaagatt ttctcaatcg tcactccagc ttggacagct tcttcaaaca agtgccagcc
    50461 ttcaatcaag taggcagact tgcggtattt tttttggcgt aatttcttgg cattttttac
    50521 cacagaattg gcttttgagg ttataatagt catagaaata ttataacaca atcaaagggg
    50581 tttggtatgc aaaaggttag aatgattgcc caaggtaggg tacagggagt cggctttcgt
    50641 tggggtgttt acagcttggc acttgaaatt ggtggcatca caggtcgagt atggaataac
    50701 gacgatggca cagtggaaat cttagcccaa gcagactcat ctgctatcat ggcaaaattt
    50761 atccaagaaa tccgaaaagg accgacacct ttttcaaaag taagctactt agatgtcaaa
    50821 ctaagcaact ttcctcccta ctctgacttt aaaatcgcaa attaggtctc cagaactatt
    50881 gtatattttg taaaaaaaca gtagaataga aaggtataat ttttaaagaa ggaataaaaa
    50941 cagtgaaatc tattaaacgt tttgcactct cagctatggg agcggctatg ttgcttgtct
    51001 tgactggttg tgtcaatgtc gataaaacca caggtcagcc aacaggattt atttggaata
    51061 ccatcggagc ccctatggct gaagctatca agtacttcgc tactgataaa ggtctaggct
    51121 ttggtgtcgc tatcatcatc gtaaccatta tcgtgcgctt gattatcttg ccacttggta
    51181 tctaccaatc atggaaggca acgcttcact ctgaaaagat gaacgccctc aagcacgtcc
    51241 ttgagccaca ccaaacgcgt ctcaaagaag cgactactca agaagaaaaa ctcgaagccc
    51301 aacaagctct ctttgctgct caaaaagagc acggtatcag catgtttggc ggtgtaggat
    51361 gtttccctat cctccttcaa atgcctttct tctctgctat ctactttgct gcccaacata
    51421 ctgaaggggt tgctcaagca agctacctag gcattcctct aggttctcca agtatgattt
    51481 tggttgcctg tgctggtgtc ctttactatc ttcaatcgct cctttcactt cacggagtag
    51541 aagatgaaat gcaaagagaa caaatcaaga aaatgattta catgagccca ctcatgatcg
    51601 tcgtcttctc cctcttctca ccagctagtg tcacacttta ctgggttgtc ggtggtttca
    51661 tgatgattct ccaacagttt atcgtcaact atatcgttcg tccaaaactt cgcaaaaaag
    51721 tccgtgaaga actagccaag aacccaccaa aagcaagtgc tttctctaaa ccaagtggac
    51781 gaaaagacgt tacccctgaa caaccaactg ctatcacaag caagaaaaaa cacaaaaatc
    51841 gcaacgctgg aaaacaacgt tcgagataag aagaaaaagg cttagctgat ttgctaagtc
    51901 tttttgcaaa tcaaaagccc gatgtttcca tcaggcttct tttctatcca tgtacacgtt
    51961 tcatataatc ttgataactt tcggtatcca tgagtttttt agcgttcttg acgcgatctg
    52021 ctgttggtgg tttgactcct tcgagggaat atggaattcc aagttcacgc cacttgaact
    52081 cacccatggt gtgataaggt agaatttcaa acttatcaac atttttgagg gtcttgacga
    52141 acttaccaag ttcaatcaag tcatcatctc tgtctgtcaa tcctggaact agcacgtggc
    52201 gaatccagac aggttttcca atatctgata gatactgggc acaagccaag atatttttat
    52261 tggtttgtct agtgacaatc ttgtgctgtt cttcgttgat ttccttgata tccaaaagaa
    52321 ccaagtcagt gacagccatg agtttgtcaa acttctcaag gtaacgtggt ttattacgga
    52381 aaggaagagc acaggtatcc aaggtacagt ggattccttg ttccttagcc ttggtgaaga
    52441 gagcaatcag gaaatcaatc tgcaagagag cttctcctcc actgactgta atcccaccct
    52501 tatttcccca gaaaccacgg tagcgcaagg cctctgtcaa gacatcatct accgtccgtt
    52561 cacgtgactt attggactcc atagcccaag tgtctgggtt gtggcaatac tggcaacgca
    52621 tgtgacagcc ctgcaaaaag acaataaagc gaataccagg cccatctact gacccaaagc
    52681 tttctgtcga atgcaccatt cctgtcactt gtccataatc aattgtttct tcagacatat
    52741 cgttaccttc cttgaaaacg ttttatagtt ttattatatc acgacttgaa ggaaaaacaa
    52801 gatttttgcc tattttttag aaagcaatct gtttttcaat ttcattttca atctattatc
    52861 agattattct tcaaaatcga agccatataa ggttgcaaaa tagtcctcag ggcgctctgc
    52921 acggcggatt tgacgggctt taccttcttc ggtatagagg atttccgcag aacgtaattt
    52981 ggcattatac tggtagccca ttgaaaatcc gtgggcacct gtatcatgaa ttaccagcaa
    53041 atcaccgatt tctgtatgag gcagttcgcg attgactgca aatttatcat tgttttcaca
    53101 gagtgaacca accacatcta ccgcttcagc tggtccatct ggatgggtca cgttgctaat
    53161 atgatggtaa gctccgtaca tagctggacg catgaggttg actgctgagg catccacacc
    53221 tagataggta cggtaggttt ccttcttatg agtcactctt gtgactagag caccgtgagg
    53281 tgccagcata aaacgaccca attcggtgaa aatcttgacc tgaccaagac ctgctgacgt
    53341 aagaacttct tcatacacct tacgaactcc ctcaccaatc aaggcgatat cgttcggctc
    53401 ctggtctgga cgataattaa caccaatacc gccagaaaga ttgataaagt ctagccaaat
    53461 gcccaacttt tccttgattt caacagccag ttcaaagagc tgacgagcca actctggata
    53521 atagagatgg gtcacggtat tggacgctag gaaggagtga atcccaaaag tcttggctcc
    53581 tttttccttc aagatagcaa aggcttcaaa gagctggtcc ttggtcatgc caaacttagc
    53641 ctccccagga ttgtccataa tgtctgtccc cagttcaaaa acgcctccag gattataacg
    53701 acaagagatg atttctggaa tgcctgctac tctctccaga tgttcaatat cttcaaaggc
    53761 atccaagtta atggtcgcac ccaattcacg tgcataggcg tattccttgt ctggcgtgtt
    53821 gttggaagag aacataatct cagaacccag aaagtccagt ttatggctca tcaaaagctc
    53881 tacataacta gagcagtcca caccacaacc ttcttcttgg agaattttca aaatagctgg
    53941 agttggagta gccttaactg caaaatattc cttaaagccc ttgttccacg aaaaagcttg
    54001 gttgacggct cttgccttct cacgaatccc cttctcatca tacaagtgaa agggagtcgg
    54061 gaactcggca acaatcgctt ctaactcttc tctattgata aatggtgttt tcataagctt
    54121 ccttctattc tgtttgcaaa gaaaggctgg gacaatcgtt ccaaccttta gttctatctc
    54181 ttatttatct tcgtcaaaga tattgccaac ctcaacatcg atggcttggt tcttgacatc
    54241 aatattagtt accttcaaga gtgacttgta gtcaaactgc ttttcacgtt cttcttgggc
    54301 attgtccgca aagaccgcta cacctgccag ttctgagtcg aactcgcgca agagactaat
    54361 cataccgttg accgttccgc cacctttcaa gaagtcatcc acaatcaaga cacggctacc
    54421 tgccttaaga ctacgttttg aaaggaacat tttctcgata cggtcaccac ttgaacctga
    54481 aacatagttg acgctaacag ttgaaccttc ggtaattttc aggtcacggc gcacaatgac
    54541 aaaagagaca ttgaggacat tggcaactgc atttgcaagt ggcacaccct tagttgctac
    54601 ggtcataacc gcgtcaattt tttggtccat aaagcttttg gcaataatac gaccaatatt
    54661 tttcaagatg gctggtgtgc taagcaaatc agacagatag atataaccac ctggcaagat
    54721 acggtcactt tctgacaact tggtacgcaa gtcttcaacc atttccttag catcctgact
    54781 cgaaatagac ggtgtgaaga tgacacctcc gccagcccca gtcactgtct ggatatgacc
    54841 gatttcaatt tcctcaaagg cgcgtttgat aatgacgata tcttctgaga tggatgattt
    54901 agcagactca tacttttcag caaaagtatt gagactagtt agtttataag gattattaat
    54961 caaatagttg gaaatgacaa ccatccgatc acttcttctt aatttcattt ctatttccta
    55021 ttccattttt attcaaaaaa tcaaaaagca aactagaaag ctggtcgctg gtggttcaaa
    55081 acactgtttt gagattgtca atagaactga caaaccctgt aatatacctg catatataca
    55141 tacgacaagg cgatactacc ctagtttgaa gagattttcg aagagtattc atttttgtct
    55201 tttacttatt ataccatatt cacataaaaa aacgaacatt cttatcctaa aaaatgctca
    55261 tttttcttaa attattaatc taaatctggt ttatagaagg aacgattatc catagcgaag
    55321 attttattgg tcatctctcc tttatccacc aaagcaagag ctgttgacat catcatcatg
    55381 cttgcatcca gattgtcaat catatggata atctctgctt ccataatgcg tggacggact
    55441 gggcttccat actcaagcaa gccgtggtga ctgaggatga catgacgaag caaaacgact
    55501 tcttccttgg tatcatcgat gccgagttcc ataactgtct tggtaatttc gctatcaatg
    55561 agagcgatat gtccaagaag attacctcgc actgtgtact ctgtctggtc tggccccgtc
    55621 aactcgatga ccttagctaa gtcatgcaac ataatccccg catagagcag gctcttattg
    55681 agctgaggat aaacttcgct aatagcgtct gccaaacgca ccatggtcgc cgtatgatag
    55741 gccaagcccg tttcaaaggc atggtggttg gtcttggcag ctggatagga gtagaattcc
    55801 ttatcatact tggtgtagag atttcggaca atccgttgcc agacaggatt ttcaattttg
    55861 aaaatcattt gcgacatgta gtcacgaatt tccttgacat caactggtga cttgaccttg
    55921 aaatcggctg ggtcattggg ttcaccagct tgaggcaggc ggagagtaat ttgattgact
    55981 tgaggggtat tgttataaac ttctcggcgt cctttcatgt ggacaacctt acctgcggta
    56041 aaggcctcaa tgttatgagg ttgggcatcc cagagcttcc catcaatctc gccactatca
    56101 tcttggaagg taaaggctag gtagtttttc ccagctcgag tttgcctcag gtcagctgat
    56161 ttgattaggt aaaagccttc aaatagctca tcttttttca tgtgactaat cttcatattc
    56221 ttcctcattt tcttgaaaat ggagtagatc aagcgcaggc tcgccttctg acaactcaat
    56281 gtgacggagc gtccgctcga tagctatggt acgacggttt aataattcat caatattgcc
    56341 agaggcatgt tggagatgtt tttgtgcctt gaccagaata ccaccaaact tgccaaactc
    56401 ggtcttgaca ctggcaagag tcttgctgat atggtcggca ctcttttgga tattaagggt
    56461 cttgaaacca actgataggg agttaagaag ggctgatagg gtacttggtc ctgcaacgat
    56521 aatctgttct tcccgtctca aatcatcaaa gaagaccgga ttgcgcacaa tctctgaata
    56581 aagaccttct gtcggaacaa acaaaactcc aaaattggtc gtccgaggcg gtgctatgta
    56641 cttgctcttg atatccttgg caaagcgctt gacgcttgct aggagtgact tacgacagcg
    56701 ttcaatctca tccttgtcac ctgtctcata ggcttcttcc aagcggtaat aatctgccag
    56761 tggaaactta gagtcaattg gcagatagac gtattcttgg tcgccttgtc cgggtaactt
    56821 gatggcatac tccactcgtt cactagagtt ttcaaccgtt gcgtattctc gttcgtactg
    56881 ggcaggtgtc atgatgtctt caataatttg ccccagttgc aattctccca gaatccctcg
    56941 cgtcttggtt ccagagagaa ccttgttaag agctccgaca tcacgggcaa ctgtctgcat
    57001 ttctccaagg ccacgattga cagactccag ttgtttagaa actgtctcaa aggaagcctg
    57061 taagcgtgtc tgcaaggtct tttctagttt ttcctcgacc gtctggcgca tttgttccaa
    57121 acgttgctca tttgattcct gcaaggcttg gagacgttgg tctgtcttgt ctctagtttg
    57181 gaggagatta tctgtcattt cttgacggac ttgggtcaga ccttggtgca attcaatccg
    57241 cacttcttgc aaacggtcgc ttacaaccac ttccaaatct ttttggtcta actggctggc
    57301 ttgtctggct tggtcaaagc ggtaatccaa ctggtctgac aaatgatctg cctgatcctc
    57361 caagctctta cttaagtgtt tctcctgcct atcctgcctt tgccaaatca gaaagagacc
    57421 agctaggttg gcaattaata atagaataag taaactttcc atcctacctc ctgtccttgc
    57481 tatgcagtac gaccacataa ccatctgggc aagttaccga cacttcccta tctatatatt
    57541 cgttagaagc gtacactttt ttaaagaaaa aattttcctc tgtcaactca tacttggctc
    57601 caagaatagt cagctggcta tcccgaactg gcataaaggc tagatagtcg tagcctgaac
    57661 gaggttctag ctgactggtc ccttctggac aataagtaat caagttttgc ccatcctcaa
    57721 tttctatttg atgcatatag ggtgccaact taggattgct aggcagaaag acattggcca
    57781 acatatggtc aatacggcca cccaaggcac cgaaaatagt aacctgagcc tgaggatttt
    57841 tctcaaagat ggttaagaga gccaattcca aatcggtatc atctttttct ggtcgggctt
    57901 ggacaaaatg ctgggcacgt ttttgaatca cctgtcgctc ttcttcggtc acagaatcaa
    57961 aatccccaac tgctagagca agaagcaagt cttcttccaa gacccagagc gagcctcgat
    58021 ccaccccaac aaaagcatca aaatctgtcc gataatgacc gcggtctccg cctgcaaaaa
    58081 cggcaaccct agtccagttg ttttctgaga gtttgtactc gctcattgac atctccctta
    58141 aagacatagg aacctgctac aaaaacggtc gcaccagctt ctttggcttg ggcaatagtt
    58201 tggtcatcaa tcccaccatc cacttcgatt tcaaagttca aacctttttc ctcacgaaga
    58261 gcaaccaact cacgaacctt atccatggtt tctggcagaa aggcttgccc accaaaacct
    58321 ggattaaccg tcatgactaa aacttggtca actagatgaa ggacgtgctt gatggcttca
    58381 actgatgtgc caggattgat aacgactgaa ggcttaactc cgagtgaacg aattttttgg
    58441 agggcgccat gaatatgagg cgttgcttct acatggatac tgatgatgtc tgcacctgca
    58501 cgcgcaaaat cttccagatg atgctcaggg tttgacacca tcaagtggca atcgaaaacc
    58561 atcttactat gaggacgaag gctctcgacc acacctgcac caaaactgat ttgcggtaca
    58621 aaatgactgt ccatgatatc gatatgggca tattctgccc cagttgcttc tagacgtttg
    58681 atttcacgtt caaagttggc ataatctgct gccagaattg acggagcaat cttgtattga
    58741 gacataggtt tctccttatt ttggaatttt tttgctgact tttttatagg tttctctacg
    58801 attttcaatt tcactaagga attgcaggta attgtcaaaa cggaaggttg caataacacc
    58861 ctcttcaaca gctggtttga cggcacaaga cggctcatgg gtatgggtac aagtacggaa
    58921 cttacaatct cggctaacag tagcaatctc tggaaaggcc tgattgaggt cttcagccct
    58981 tgatacttca tagtccagag atgaaaagcc tggtgtatct gcgattttac ccccgttgag
    59041 attgtaaaaa ctaacagctc gagtggtatg gcgaccgcga cctagactgt ctgaaatttc
    59101 tcccgtttca agattgaggt ctggtgcgat tttattgaga agagttgact tcccaacacc
    59161 tgtctgcccc ataaagaccg taaccttgcc tgttaacaaa gacaggagtt cctctttact
    59221 ggtcacaaag tcatagccga tgtcaccata ggtctgctgg taaaaatcca gttctcccct
    59281 atcttccaac aaatccattt tggaaatata gacaatggga tggatgccct tgtgctccaa
    59341 aagaaccaag aaacgatcca gcaaattgct gttaaaatca ggttccttga cggacatgat
    59401 tactacagct tgatcgatat tgacaatagg cggacgaacc agactgtttt tccgttcgtg
    59461 aattttgagg atatagcctt ctgaattttc ctcggcagag aaatctaccc agtccccaac
    59521 ataaggggta tggccttttt tacggaaatt cccacgcgcg cgtgtttgat aaacctggcc
    59581 atcactctcc acatagtaga aacctgccaa ggctttaatg atttgtccct gcatcttaga
    59641 gtccttgccc tttaagtgcg tctgctagac cggcaaattc tgccaagctg agagcttccc
    59701 cacgcacact tggtgacaag cctgcctggt ccaaagcctt ggtcagcttg tccttgacct
    59761 cttcagtctt accaaagtaa cctgtcaagt tattccacaa ggtcttgcgg cgatgggtaa
    59821 aactagcctt ggaaacctta aagaaaaagt tctcatcttc tactgctacg gctggctctg
    59881 gacgacgcac cattttcaag atggctgaat ccacatttgg cgctggcaca aagaccgtac
    59941 gaggcacgat aaaggcaacc ttggctgtca tgtaatactg cacggcgata gacaagctac
    60001 cgtaagcctt ggtgttaggc tgggctgaaa tgcggtccgc tacttctttc tgcatcatga
    60061 ccacaaactc acaaaaagga atgccactct caatcaagtg catgagaata ggcgtcgtga
    60121 tgtagtaagg caaattagcc actaccttga ttggcaggtt aggattttta aaattttgga
    60181 tatgttgcgc caaatcaacc ttgagaatat cttcgttaac tacggtcaca ttatcaaaat
    60241 cacgcagagt atctgccaaa attggcatca aacggtggtc aatctcaaaa gccatgactt
    60301 gggctgcacg ctcagccaaa aattctgtca aggcaccaat acctggcccg atttcgatga
    60361 cattgacctg atcatcaatt tcagccgtat ccacaatttt ttgaaggata ttggtatccg
    60421 tcaagaaatt ttgcccaaag gactttttaa aggtaaaacc gtgacgctcc aacactgcct
    60481 tggtcacgct ataatctgca attctcatct attctctttt ctattatctg ttactactat
    60541 tgtaacacat tccccttgta ttttgggaat gaaaatcata ccaaaaaact atctttcctc
    60601 atgaagaaag atagtcttgg aaatctttaa agagggactt agtgcttctc tcgaaacata
    60661 cgttcatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtactcaagt
    60721 acagcctgcg gctagcttcc tagtttgctc tttgattttc attgagtatc aaaaaaatca
    60781 gcttcttgat aacttcgatt ttcgggtagg gtcaaatcca catcctcctc cacatcatcc
    60841 actgtcagtt caaccgtctg aggtaaattt ttcaaacgat aatgcttttg cctttgccct
    60901 tcaatactag caaaatcaag caaatagcca tgcactcgga tttgaaccaa aaggagatga
    60961 ttggtcatat tttccatgat gaggatatct tctaaaccac ctctggcact aggataatca
    61021 gataccctgc gaatacggat tttttcacac atgagcaagt ttcctcatat caatgatttc
    61081 atcagcctta ttccagacta ggggattatg ggtcgcaatg atgataattc gattttcatc
    61141 tttcaaatcc accaagagat tcataacctc ctctgaattt tcaggatcaa gagctgctgt
    61201 tggttcatct gccaaaatca agggtggatt tttcaaaata gtcttagcaa gggcaactcg
    61261 ttgggcctct cccccagata aagtataaat tttttgttct aaatccaaat accctagatt
    61321 aactttttct aaagccccca cttgcctttc caaacgttct acttttgaga ttttctgacc
    61381 aacaaaaccc aaatccaaat tttctttgat tgattggttt tctaagaggc cgaaattttg
    61441 aaagagatag cccatctggt ctcgaaaata ctcacgagta ggaatggttt ttaaatcttt
    61501 cccctgatag agaacccttc caccatctat cttttctagc tttcccaaga tattcagcag
    61561 cgtcgtcttt ccgcttccac tctttccgat taaggcataa accttgccct tctccagctt
    61621 gagattcaaa ccagagaaaa tcgcgcggtc attaaatttc ttttccaatc cttgaatatc
    61681 aatcatctta ttttcctttc aatactgcca tgctaccagc ttcttctttt ttatcctgcc
    61741 ttactaaaat caagagggcg ttaagcgtaa acaaagctac aactagagcg ctaatcaaac
    61801 catctcttgt caaaatacta gataggacta ggccaagcaa gagaactcct ccttgcgcca
    61861 gtaaatactt gccatgaagc tcatagattg tcataccagc aagacgttta atcataagtt
    61921 cccgtctgaa ctgctcaaaa tagagaagat tcatggaatc aaataacaag atagccgtag
    61981 acagggtcaa aatcgtccca ataaggagag agtaaaactc cacccgtttg tcatttagta
    62041 ccttggcaaa aaatagctgg ctttttacca agtaagaaac cttgtgatac agaccttgct
    62101 cttttagagc tgtgatgctg tctccatatc gatctagttt caaggcacta ttagccgtag
    62161 ttccccacaa catccctgca acaggtcttg ttccagtcgc ttgcggcgtt agaactacaa
    62221 taatcggatc ttttaggtac tggcgtgttg tcttgtaccc atcattatag aggaaacgtt
    62281 cctgtcctgt ttctgtaaaa gctagcctta cctgtgggag gtagtgtttc tgactcgtca
    62341 cttctacact ttcagatgaa aagttttgca ggtaatctgt aaacaatcct tggtagtagg
    62401 cagactgctc tcgcaagctc tcaggcaaga tcagcccaaa ctctccctca gacaagtttt
    62461 gcatcttgtc cataaactct gaagaaacgg taatcttttc ttctatcaga tagcgcggcg
    62521 agacatagat aacattccct aacggtgtgt agtcactgag acgattgcca tctaggtcca
    62581 cttctgctcc atctgagaaa ttgtcaacat tgctcataat ataaaaagag tctgtattgg
    62641 ctaaccgttc ttcagtaaat gtctgccact cacgattatc cttacgcgtt ccttcttcat
    62701 cggcaaatgc actagaccaa ccaaaggata gacggtaacg gtctgaggac tggctccatt
    62761 tattgctagc tctctccatt tcctgcattt cacggtagtg gggtaggaga gctgtcgcac
    62821 tcgatccgac caccaataca gctaagagtt gccccaccat catcaatgtc atcatacgtt
    62881 tgagagggag tttccctttc aatagatcca ccagactatt ttcctgtaaa ccaagtagat
    62941 agacgacact tagtaaggta gaaatccctg ccaaggtcaa tccataaagt agaagagcaa
    63001 tgatgaccag ttgtaccgtt gccataaaca aggcaccttg ataccagaga atccccaatc
    63061 ccaaaagact ggataccagc actgagcaga taagctgtct cacatcttct aacactggtc
    63121 tgagagcaac tccaaacaag ctctcaccag ctattaagcg aatccctgcc tgacgaaggg
    63181 atttgatccg ataaatcagg gtcagactca taaaggtcag cagaaaaata gctaaactca
    63241 gtagcaccat aggggtggcc gccaatagta agactatcga aaatggatct tctccattcg
    63301 aaacaaagcc ttgataacca agctctttca aggtggtctg taagctcact ccatccaaac
    63361 ttcctgacac aatcaagtaa gaccctaata aatcactcgt ttctgcactc tccttggagg
    63421 aaatggtcag accttctgga agctctccct caccataagt ggcataggta aagagtgttt
    63481 ctccagcttc atttggctca acgattcgac gggcgatgag actattatgc tctaccgcca
    63541 agtgactcaa agcctctgtc acctcttcgc gactagctac tggttgattt atcatcattc
    63601 ctgtcacatc aacagaagga tagttaccaa ataaaatctc ttctcgatgg tcaacggaag
    63661 ttatcaccat ataaagcgat accaatacca ttgaaatcaa aataaataaa cgtttcatca
    63721 tttcctccaa aaagttactt ggtcacttag tgagaaggtg accaagtaaa gctaaacaat
    63781 agggctatac cattctaaac attatagtag aatgcaactt tctctcccca agaagtacga
    63841 atccatgcac gagaagtccc tccagcacca gcatatccct tgtcagatga accagttttt
    63901 ctgctaacaa ctgttgaact atggtatttt gaagggtgat agtagtttga gtaagcacca
    63961 ccgttacctg aaccataagt ccaaacacca ccttctgggt attgaacggc tgcagaggca
    64021 actgatacac ctccacctaa tgttgctgca atgctcgcta caagagctaa ctttttaact
    64081 gtttgtttca tattgatact cctctatttt tgattacaag attgttgagt tacttgctcc
    64141 tctttccatt atcaacgttg atactattat attaccaaat gatattctaa aattatttgt
    64201 ttttctctaa attgtcaaaa tagcaccctg aaatgaactt ttatagtcat tatactccat
    64261 ctttatcaca ctatcaagga catcaatgtc cttaaaatct aactatttca tattattttt
    64321 agcttatatc taaaaaaaca gttctaaaga cgaactttag aactgttttg atacgaggac
    64381 aaggacattt ttgtcactga ttcactatgt ttataaatat tttttgacat cctcttgcca
    64441 ttcctctgtc aatttcttta ctagaaatcc atctccaatt agcttcgcaa atgttttaga
    64501 agactgataa aatgattcag ctaaactaaa atctctttct actcttaatg cttgcttcca
    64561 caaaaacata aatacaagag gtttcttttg ataatcttga gttttatcca taatttcttg
    64621 taaacacgat agataatcat taaaacaatc agttactcct accttttcaa gacaacacat
    64681 tcctgaaata agagtatctc taattataaa gaagttttct aatttagtta cctttttctg
    64741 ttccaaaaga aagagcatta gcttttcgat ttgatttata aatttggcaa gatcttttct
    64801 aatgagcatt tgataaaaaa acaaacgaat caacaacata tcatttgttg aataaacttc
    64861 tttttctatg atctgagaca tatgttcctc aagtattaac tctgcatatt caggccttct
    64921 agttctagaa gtatccaaac acgcttcttt cttatcatac tcctcttctt taccatagat
    64981 tggttcacgt aaaatctggt atttcaattc taaataagca gaaggaagag ctgaaaaatc
    65041 cggcataagg ctataaactg gaactcctag ccggcgagca atataggcta acttgggcaa
    65101 actcggttgc gaagctccac tttcaattcg cgacagttga cgaactgtca gttcttgctc
    65161 atctccacaa aaatctggac gactaattcc tttttctatc cgaatctctt taattttttg
    65221 accaattaac atcagacgcc tcctcttcta cctgcttcga aaaatactgt gaaacttaaa
    65281 aaattgtaac ggctacatct ttcctactca taagatttca tagcttcttc cacttctgcc
    65341 aaagtaaccc caaacaactc taggcgtttg aggagttgct tgccattaga atagccgatt
    65401 cggagagtct ctccgagata ttctctacgc ttacggctgt ctgcccctgc tagaaaacca
    65461 aggcgaatca agtcgctacg actaatgtca aactgactct catgttcaaa ttgttctgtc
    65521 acctgagcta gagccgtttt caggtcttca tagctggcat gctcaattcc cagagaacgc
    65581 cccttggtct tggacttggg aacagcttca tctcgcttga gaaaggcatg ctgaactgtt
    65641 ggaatggccg tcataatcat gcgccgaatc cgctccccat taaaatctgg gtctgtaaag
    65701 acaatgactc catgacgttg gtgtagacgc tgaattcgct ctatatcctg atcattgatg
    65761 gcagaacctc gtgtctcata ggtctccaca tcgaaataac gcttgagatt gaccgtatca
    65821 tagcgacctt caaccacgat aacttgagaa attttctctt tcattacttg ctgtccaatc
    65881 caaaaattcg ttctgcattt gcagtcgttg ctaccgccag ctcttctgtc gtcataccac
    65941 gcaagtcagc gataaagtcg accacatagc gagtataggc tgttttattt tcacgaccac
    66001 gcttgggtac aggtgctaag taaggcgcat ctgtttccac caacatcttg tccaaaggta
    66061 actctttagc tgcttcttgg aggtcagttg ccttcttgaa agtcaccact cctgagaagg
    66121 aaatggtcat accaagatcc acaaacttct ctgcccactc aagcgtccct gaaaatgaat
    66181 gcatgatacc accacgagga ccaacgccct cactcttgat aatctcatag gtatcttcca
    66241 gcgcatcacg ggtatggaca acaaaaggca aatccaagtc cttagatagc tgaatctgac
    66301 ggcgaaaaac ctgctcctgc acctctttgg gcgctgtcat ccaatggtag tctaagccaa
    66361 tttcacctaa agccacaacc ttggaatgtt ttaacttatc caacaagtaa gcctcaactt
    66421 cctctgtata agtaccagct tctgtaggat gccaaccaat agtcgcatag agctgctcat
    66481 actcatctac caactccaag gcacgctcaa tcgtcggttt atcaaaacca acaatattca
    66541 tctgtatcac acccatctca gcagccaagg caatttcttc tgcctcacga cctgcaaatt
    66601 cttctacatt caagtgtgta tgtgtatcaa aaatcatctc ttctaacctc gttttctatc
    66661 ttctattata ccaaaaaaga ggaggggcac ctaatttttc ggtttcccct cctctcttca
    66721 atagagagct attctgctat cttttctatc cgatattgcc catctcctat tccacagtta
    66781 gagacagaag agattggcta cattgataga atattcctat tcagctaaag tatgtgatta
    66841 tcttgggttc tcacttttct cacccatcac taggattgat gacttctcaa aatccccctt
    66901 ataatctaac tttaagtaga gaatagaatt ttctagctgt tctattttct acgtctagtc
    66961 tttcttccta gcaaagcaaa accacttgtt gccaccacta gaccaagact agcaagtgct
    67021 gcacttgatg ctgaacctgt gttaggtaat tgtttgccag caggtgactg gtaggtaaca
    67081 tcttgcattg ttcctgcagt tgcttgcggt gcacttgttg tcttaggagc agcattagga
    67141 gccactggtc tcttaggaac tgtaaccatg gcaatggctt gcactccaat cgtttctgct
    67201 tccttcacat cttccatagt tttcgcattt tcaatctctt tgagagctgc ttgtttttct
    67261 gcttccactc ttgctaaaag ttctgctttt tctttatcag aaagcggtgc gcctttgatt
    67321 tcatcctgct tatccttggc tgctttttca atggcatttt tagctgattc tttttcagta
    67381 gctaattgct tagaagcttg tgattgagct gagttttgtg aacctgtgtg agctgatcca
    67441 cccgcctggc taccaccgcc ttcattcgca ttagcatctg agcttccagt attgcctccc
    67501 ttatctccac ctggtatagt ttctagctta tactctagtg tagcttcttg agttacagat
    67561 tcacctttcg cagattgttg aactgtatct tttcctagaa tcgtcactac tgaaccatct
    67621 gggaatgtga ttgttgctgt accatctcca cctacattga ttgtcgctcc gtctaatgct
    67681 gaaccatttg cttgtaaaat agcaacctta actttttctt catctgttaa atgagttata
    67741 tcttttacat ctactctttg agcaggtgct ttaacagttg atttttcagc agtcggttta
    67801 gtgctatctt gtgcttttgg atcttgtgct accaattgat ttcctggaat tgtaatagct
    67861 gaaccatctt taaagacgat tgttgctgta ccatctccac ctacttcaac tttatagtaa
    67921 aataaaataa taacaggaca aatcgatcag gacagtcaaa tcgatttcta acaatgtttt
    67981 agaaacagag gtgtactatt ctagtttcaa tctactataa catcgcttcc gaatccattt
    68041 gcatctactg aactttttta caaaaataaa aatcagtaga ctcgagttcc tactgatttt
    68101 tgatagaatt cgtttggatt atgcagccaa aactttgcgt cctttacgac gacgagctgc
    68161 caatacgcga cgaccatttt tagttgacat acggttacgg aatccgtgtt tacgcgcacg
    68221 acgaagttta cttggttgat aagtacgttt cacgatgaat acctcctcat agattttgta
    68281 ttcgtttagc cggctataaa gtgatcagtt actaaacata ctttactatt ctatctgatt
    68341 ctttcacttt tgtcaatagc tctaggcaaa tgtttccagc tttttcgaat gcaagcccta
//
LOCUS       DAVLCS010000007        67223 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLCS010000007 DAVLCS010000000
VERSION     DAVLCS010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67223
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.007"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            2..74
                     /locus_tag="VXC78_000510"
     tRNA            2..74
                     /locus_tag="VXC78_000510"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            99..171
                     /locus_tag="VXC78_000511"
     tRNA            99..171
                     /locus_tag="VXC78_000511"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:132..134,aa:Lys,seq:ttt)
     gene            177..258
                     /locus_tag="VXC78_000512"
     tRNA            177..258
                     /locus_tag="VXC78_000512"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Leu,seq:tag)
     gene            277..349
                     /locus_tag="VXC78_000513"
     tRNA            277..349
                     /locus_tag="VXC78_000513"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Thr,seq:tgt)
     gene            372..443
                     /locus_tag="VXC78_000514"
     tRNA            372..443
                     /locus_tag="VXC78_000514"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:404..406,aa:Gly,seq:gcc)
     gene            451..536
                     /locus_tag="VXC78_000515"
     tRNA            451..536
                     /locus_tag="VXC78_000515"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:485..487,aa:Leu,seq:taa)
     gene            546..619
                     /locus_tag="VXC78_000516"
     tRNA            546..619
                     /locus_tag="VXC78_000516"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Arg,seq:acg)
     gene            635..708
                     /locus_tag="VXC78_000517"
     tRNA            635..708
                     /locus_tag="VXC78_000517"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:669..671,aa:Pro,seq:tgg)
     gene            714..787
                     /locus_tag="VXC78_000518"
     tRNA            714..787
                     /locus_tag="VXC78_000518"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:748..750,aa:Met,seq:cat)
     gene            801..874
                     /locus_tag="VXC78_000519"
     tRNA            801..874
                     /locus_tag="VXC78_000519"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Ile,seq:cat)
     gene            885..974
                     /locus_tag="VXC78_000520"
     tRNA            885..974
                     /locus_tag="VXC78_000520"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Ser,seq:tga)
     gene            985..1058
                     /locus_tag="VXC78_000521"
     tRNA            985..1058
                     /locus_tag="VXC78_000521"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1019..1021,aa:Met,seq:cat)
     gene            1062..1134
                     /locus_tag="VXC78_000522"
     tRNA            1062..1134
                     /locus_tag="VXC78_000522"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1095..1097,aa:Phe,seq:gaa)
     gene            1154..1224
                     /locus_tag="VXC78_000523"
     tRNA            1154..1224
                     /locus_tag="VXC78_000523"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1186..1188,aa:Gly,seq:tcc)
     gene            1260..1333
                     /locus_tag="VXC78_000524"
     tRNA            1260..1333
                     /locus_tag="VXC78_000524"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1294..1296,aa:Ile,seq:gat)
     gene            1340..1427
                     /locus_tag="VXC78_000525"
     tRNA            1340..1427
                     /locus_tag="VXC78_000525"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1374..1376,aa:Ser,seq:gct)
     gene            complement(1531..2837)
                     /locus_tag="VXC78_000526"
                     /pseudo
     CDS             complement(1531..2837)
                     /locus_tag="VXC78_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2983..3918)
                     /locus_tag="VXC78_000527"
     CDS             complement(2983..3918)
                     /locus_tag="VXC78_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV0582653.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLQQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(3915..4775)
                     /locus_tag="VXC78_000528"
     CDS             complement(3915..4775)
                     /locus_tag="VXC78_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0582654.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKDKIVYLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            4883..7045
                     /locus_tag="VXC78_000529"
     CDS             4883..7045
                     /locus_tag="VXC78_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0582655.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            7137..8396
                     /locus_tag="VXC78_000530"
     CDS             7137..8396
                     /locus_tag="VXC78_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0582656.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNAYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTSFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            8410..9276
                     /locus_tag="VXC78_000531"
     CDS             8410..9276
                     /locus_tag="VXC78_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0582657.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            9300..10133
                     /locus_tag="VXC78_000532"
     CDS             9300..10133
                     /locus_tag="VXC78_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0582658.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     VFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            10134..10214
                     /locus_tag="VXC78_000533"
                     /pseudo
     CDS             10134..10214
                     /locus_tag="VXC78_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            10491..11933
                     /gene="gtfA"
                     /locus_tag="VXC78_000534"
     CDS             10491..11933
                     /gene="gtfA"
                     /locus_tag="VXC78_000534"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV0582659.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            12071..13264
                     /locus_tag="VXC78_000535"
     CDS             12071..13264
                     /locus_tag="VXC78_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0582660.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            13950..15929
                     /locus_tag="VXC78_000536"
     CDS             13950..15929
                     /locus_tag="VXC78_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0582661.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            15996..17492
                     /locus_tag="VXC78_000537"
     CDS             15996..17492
                     /locus_tag="VXC78_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0582662.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            17492..18418
                     /locus_tag="VXC78_000538"
     CDS             17492..18418
                     /locus_tag="VXC78_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0582663.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            18427..19494
                     /locus_tag="VXC78_000539"
     CDS             18427..19494
                     /locus_tag="VXC78_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582664.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            19505..20431
                     /locus_tag="VXC78_000540"
     CDS             19505..20431
                     /locus_tag="VXC78_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582665.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            20998..21858
                     /locus_tag="VXC78_000541"
     CDS             20998..21858
                     /locus_tag="VXC78_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0582666.1"
                     /translation="MSQFITHQSLYATREGFVDELAKQGYVEGENIEIDLQNAQGEQR
                     NLKTISQQLAESSDVVLAIARPSAQSLANTTQTTPVIFSAVTDPVSAKLVESREHPGG
                     NVTGTSDQSSDAISTQINLIKKVLPKAKTIGILYTQSEPNSVVQKDEAKRLLKEKGFT
                     VVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISLTMETVKQVSIKHKVPVFGGSTE
                     MIAVGGLYNYGTNYEELVRQTARMLIRVLKGEKPENIAVELPEKLELHTNQEMADALG
                     IDISKLEGKE"
     gene            21870..22763
                     /locus_tag="VXC78_000542"
     CDS             21870..22763
                     /locus_tag="VXC78_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0582667.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLAGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            22776..23579
                     /locus_tag="VXC78_000543"
     CDS             22776..23579
                     /locus_tag="VXC78_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0582668.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(23612..24322)
                     /gene="treR"
                     /locus_tag="VXC78_000544"
     CDS             complement(23612..24322)
                     /gene="treR"
                     /locus_tag="VXC78_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV0582669.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIREQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            24507..26474
                     /gene="treP"
                     /locus_tag="VXC78_000545"
     CDS             24507..26474
                     /gene="treP"
                     /locus_tag="VXC78_000545"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV0582670.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            26652..28277
                     /gene="treC"
                     /locus_tag="VXC78_000546"
     CDS             26652..28277
                     /gene="treC"
                     /locus_tag="VXC78_000546"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV0582671.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            28533..28781
                     /locus_tag="VXC78_000547"
     CDS             28533..28781
                     /locus_tag="VXC78_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV0582672.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            28988..29782
                     /gene="racE"
                     /locus_tag="VXC78_000548"
     CDS             28988..29782
                     /gene="racE"
                     /locus_tag="VXC78_000548"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV0582673.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            29779..30750
                     /locus_tag="VXC78_000549"
     CDS             29779..30750
                     /locus_tag="VXC78_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV0582674.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            30726..31247
                     /locus_tag="VXC78_000550"
     CDS             30726..31247
                     /locus_tag="VXC78_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0582675.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            31244..31705
                     /locus_tag="VXC78_000551"
     CDS             31244..31705
                     /locus_tag="VXC78_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0582676.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            31696..32436
                     /gene="xerD"
                     /locus_tag="VXC78_000552"
     CDS             31696..32436
                     /gene="xerD"
                     /locus_tag="VXC78_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV0582677.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            32436..33164
                     /locus_tag="VXC78_000553"
     CDS             32436..33164
                     /locus_tag="VXC78_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV0582678.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            33183..33752
                     /locus_tag="VXC78_000554"
     CDS             33183..33752
                     /locus_tag="VXC78_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV0582679.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            33739..34461
                     /locus_tag="VXC78_000555"
     CDS             33739..34461
                     /locus_tag="VXC78_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0582680.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            34461..34703
                     /gene="yidD"
                     /locus_tag="VXC78_000556"
     CDS             34461..34703
                     /gene="yidD"
                     /locus_tag="VXC78_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV0582681.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(34928..35893)
                     /locus_tag="VXC78_000557"
     CDS             complement(34928..35893)
                     /locus_tag="VXC78_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0582682.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLAEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(35989..36741)
                     /locus_tag="VXC78_000558"
     CDS             complement(35989..36741)
                     /locus_tag="VXC78_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0582683.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINIASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(36738..37694)
                     /locus_tag="VXC78_000559"
     CDS             complement(36738..37694)
                     /locus_tag="VXC78_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV0582684.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATSLVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(37684..38643)
                     /locus_tag="VXC78_000560"
     CDS             complement(37684..38643)
                     /locus_tag="VXC78_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0582685.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTNDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(39066..39767)
                     /gene="galE"
                     /locus_tag="VXC78_000561"
     CDS             complement(39066..39767)
                     /gene="galE"
                     /locus_tag="VXC78_000561"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0582686.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            40168..41232
                     /gene="pepA"
                     /locus_tag="VXC78_000562"
     CDS             40168..41232
                     /gene="pepA"
                     /locus_tag="VXC78_000562"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV0582687.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            41254..41550
                     /locus_tag="VXC78_000563"
     CDS             41254..41550
                     /locus_tag="VXC78_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0582688.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSSLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            42232..42675
                     /locus_tag="VXC78_000564"
     CDS             42232..42675
                     /locus_tag="VXC78_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0582689.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKENEV"
     gene            42679..43443
                     /locus_tag="VXC78_000565"
     CDS             42679..43443
                     /locus_tag="VXC78_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV0582690.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     CIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            43458..44186
                     /locus_tag="VXC78_000566"
     CDS             43458..44186
                     /locus_tag="VXC78_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582691.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            44179..45699
                     /locus_tag="VXC78_000567"
     CDS             44179..45699
                     /locus_tag="VXC78_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV0582692.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVSKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            46044..46850
                     /locus_tag="VXC78_000568"
     CDS             46044..46850
                     /locus_tag="VXC78_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV0582693.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(47017..47553)
                     /locus_tag="VXC78_000569"
     CDS             complement(47017..47553)
                     /locus_tag="VXC78_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0582694.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKDYETTTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFQKNQDHIASLLFS
                     KNDYFLRQLQRELEHHVYPMLAADLKQTHPSLPTSYLQHFVVTNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            47686..48576
                     /locus_tag="VXC78_000570"
     CDS             47686..48576
                     /locus_tag="VXC78_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV0582695.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGAVVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSDLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            48820..49173
                     /locus_tag="VXC78_000571"
     CDS             48820..49173
                     /locus_tag="VXC78_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0582696.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            49208..50200
                     /locus_tag="VXC78_000572"
     CDS             49208..50200
                     /locus_tag="VXC78_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0582697.1"
                     /translation="MDLRPQIIEADDVIIRVVRACVCGSDLWRYRNPETKAGHKNSGH
                     EAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGSCDNHIGNNLGGDFQA
                     EYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHAARVANVQKGDKVVVI
                     GDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVVAERGQEGITKVREIL
                     GGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRALGSTFMQNISVAGGAA
                     SATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDERKTIKSMIVIE"
     gene            complement(50246..51253)
                     /gene="galR"
                     /locus_tag="VXC78_000573"
     CDS             complement(50246..51253)
                     /gene="galR"
                     /locus_tag="VXC78_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV0582698.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            51417..52595
                     /locus_tag="VXC78_000574"
     CDS             51417..52595
                     /locus_tag="VXC78_000574"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV0582699.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            52614..54095
                     /locus_tag="VXC78_000575"
     CDS             52614..54095
                     /locus_tag="VXC78_000575"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0582700.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGISLD"
     gene            54165..54569
                     /locus_tag="VXC78_000576"
     CDS             54165..54569
                     /locus_tag="VXC78_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV0582701.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            54750..55514
                     /locus_tag="VXC78_000577"
     CDS             54750..55514
                     /locus_tag="VXC78_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0582702.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNYGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVKNG
                     QVRDPEKVTKEFKQSLFLRKNSLSVRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            55511..55807
                     /locus_tag="VXC78_000578"
     CDS             55511..55807
                     /locus_tag="VXC78_000578"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582703.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESNYENLCVMVYTLSDPDC
                     VRWLSENMEFGDEKQLSLLNKKYSWEYGDELPEWLESPKHRLLLISELLERNLR"
     gene            55804..55971
                     /locus_tag="VXC78_000579"
     CDS             55804..55971
                     /locus_tag="VXC78_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HEV0582704.1"
                     /translation="MKKYTVEITETLTRLVSIEAENPDEAERLVREKYKSCEIVLDAD
                     DFQDDETSIYE"
     gene            complement(56018..57280)
                     /locus_tag="VXC78_000580"
     CDS             complement(56018..57280)
                     /locus_tag="VXC78_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV0582705.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSTEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVVIILLINIFTKGFIKSISILIGLVVGTAIAASMGLVDFSPVAAAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKTRLPIYYAAGFLVLLGLLPKFGALAQIIPSP
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(57280..57861)
                     /locus_tag="VXC78_000581"
     CDS             complement(57280..57861)
                     /locus_tag="VXC78_000581"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV0582706.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFASAGITKVVTIEASGIAPAIFTAEALNVPMIFAKKAKNITMNEGILTAEVYSFTKQ
                     VTSTVSIARKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVEAIGIVIEKSFQE
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(57991..58086)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(58311..58697)
                     /locus_tag="VXC78_000582"
     CDS             complement(58311..58697)
                     /locus_tag="VXC78_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0582707.1"
                     /translation="MDYQAVIPEFVVSDIEKSRHFYCDLLGFTIEYERPEENFLFLSL
                     EDCQLMLEEGTKDELVDLTYPFGRGVNISFGIVDVPQLHQKLLEADYPIHRPLTKREF
                     RVGDSFIYPHEFAVLDPDGYFLRFSE"
     gene            complement(58709..59536)
                     /gene="xth"
                     /locus_tag="VXC78_000583"
     CDS             complement(58709..59536)
                     /gene="xth"
                     /locus_tag="VXC78_000583"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV0582708.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHLEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDKFFVTQVYTPNAGDGLKRLEERQVWDAKYAAYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRLADKVTKSDMIDSGARQDHTPIVLEIEL"
     gene            59670..60125
                     /locus_tag="VXC78_000584"
     CDS             59670..60125
                     /locus_tag="VXC78_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002281066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 domain-containing protein"
                     /protein_id="HEV0582709.1"
                     /translation="MKFYSYDYVLSQISQQNGIMIGFGIVLLAITGFFAFKAYRDKKG
                     TKFRELVMILALTLVAMLLVTISKYQTNQASNNQFQTSLHFIEVVSKDLGVDKSEVYV
                     NTSAATDGALVKVGSNVYRAMNGSQPDKYLLEKIELHQTDAIELVEVNK"
     gene            60122..60757
                     /locus_tag="VXC78_000585"
     CDS             60122..60757
                     /locus_tag="VXC78_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV0582710.1"
                     /translation="MTLNYMEILIKLALGLFSLVFVINVTGKGNLAPNSATDQIQNYV
                     LGGIIGGVIYNSSISILQYAVILMMWTILVLTLKWLNNNVRFVKRLIDGKPTLLIKNG
                     QIDPEACRSVGLSAADVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVV
                     TDGVIQVDVLESIGRSEEWLLDNLSKQGHENVANIFIAEYDKGAVTVVTYE"
     gene            complement(60932..61009)
                     /locus_tag="VXC78_000586"
                     /pseudo
     CDS             complement(60932..61009)
                     /locus_tag="VXC78_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            61055..62800
                     /locus_tag="VXC78_000587"
     CDS             61055..62800
                     /locus_tag="VXC78_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0582711.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQVLLLALFYLLLAAFGMYYLRYVWRMYILGTSYRLGQIMRSRLFEHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNITQRGKVSYQRIEELLSQESPVQDPEFPLDGIENG
                     RLQYAIDSFAFENEETLTNVHFSLEKGQTLGLVGQTGSGKTSLIKLLLREYDVDRGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNSKLPLSAVEEATKLAQV
                     YQDIVAMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKEMRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            62790..64541
                     /locus_tag="VXC78_000588"
     CDS             62790..64541
                     /locus_tag="VXC78_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582712.1"
                     /translation="MRNKKEQWDVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAITVLLAYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNIYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQTEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLYLG
                     ITAGTMYAFIQYINRLFDPLIKVTQNFSTLQTSMVSAGRVFALIDERTYEPLQNDGQA
                     KIQEGNIRFEHVCFSYDGKHPILDDISFSVKKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGLVLLDDVDIRNYSQEELRKNIGLVLQDPFLYHGTIKSNISMYQEISDEQVKDAA
                     TFVDAASFIQDLPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMADTL"
     gene            64714..65406
                     /locus_tag="VXC78_000589"
     CDS             64714..65406
                     /locus_tag="VXC78_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0582713.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            65449..66675
                     /locus_tag="VXC78_000590"
     CDS             65449..66675
                     /locus_tag="VXC78_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV0582714.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(67041..>67223)
                     /locus_tag="VXC78_000591"
     CDS             complement(67041..>67223)
                     /locus_tag="VXC78_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0582715.1"
                     /translation="KIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFI
                     ALNIKKERTNFVLSRA"
BASE COUNT        19302 a        12576 c        15289 g        20056 t
ORIGIN      
        1 aggtcccgta gtgtagcggt tatcacgtcg ccctgtcacg gcgaagatcg cgggttcgat
       61 tcccgtcggg accgtttaag gtaacgcaag ttattttaga ctcgttagct cagttggtag
      121 agcaattgac ttttaatcaa tgggtcactg gttcgagccc agtacgggtc atatatgcgg
      181 gtttggcgga attggcagac gcaccagatt taggatctgg cgcttaacgg cgtgggggtt
      241 caagtccctt aacccgcatt aagatataac aaatgagccg gcttagctca gttggtagag
      301 catctgattt gtaatcagag ggtcgcgtgt tcaagtcatg tagccggcat ttttagatag
      361 aagaaaacag tgcgaacgta gttcagtggt agaacaccac cttgccaagg tgggggtcgc
      421 gggttcgaat cccgtcgttc gcttagagag gccggggtgg cggaactggc agacgcacag
      481 gacttaaaat cctgcgattg gtaacgatcg taccggttcg attccggtcc tcggcataat
      541 atggagcacc cttagctcaa ctggatagag tacctgacta cgaatcaggc ggttagaggt
      601 tcgactcctc tagggtgcat ttttctattt aactcgggaa gtagctcagc ttggtagagt
      661 acttggtttg ggaccaaggt gtcgcaggtt cgaatcctgt cttcccgatt catggcggtg
      721 tagctcagct ggctagagcg tccggttcat acccgggagg tcgggggttc gatccccttc
      781 gccgctataa tgatcttgtc ggacctttag ctcagctggt tagagctctc ggctcataac
      841 cgagtggtcg taggttcaag tcctacaagg tccatttgaa tattggagga ttacccaagt
      901 ccggctgaag ggaacggtct tgaaaaccgt caggcgtgta aaagcgtgcg tgggttcgaa
      961 tcccacatcc tccttttata ttaacgcggg atggagcagc tcggtagctc gtcgggctca
     1021 taacccgaag gtcgtaggtt caaatcctgc tcccgcaata aggctcggta gctcagttgg
     1081 tagagcaatg gattgaagct ccatgtgtcg gcggttcgat tccgtctcgc gccattttat
     1141 tgatagtatt tatgcgggtg tagtttagtg gtaaaactac agccttccaa gctgttgtcg
     1201 cgagttcgat tctcgtcacc cgctttgaac tttgttcaaa ttaccaagtt ttttaacttg
     1261 ggcgcgtagc tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt
     1321 ccactcgtgc ccattaattg gagaattact caagaggctg aagaggacgg tttgctaaat
     1381 cgttaggtcg ggtaactggc gcaagggttc gaatccctta ttctccgttt taatgagagt
     1441 ttgtaactct cttttttgtt tttagagaca ataaaacttc agatccgtaa acttaaggct
     1501 ctttgtcaac tgtagtgggt tgaagaaaag ctaagctcga gaaaggacaa atttcgtcct
     1561 ttcttttttg atgttcagag cgatgaaaat ccgttttttg aagttttcaa agttccgaaa
     1621 accaaaggca ttgcgcttga taagtttgat gagattattg gtcgcttcca gtttggcatt
     1681 agaatagtgt agttgaaggg cgttgacaat cttttcttta tctttgagga aggttttaaa
     1741 gacagtctga aaaataggat gaacctgctt aagattgtcc tcaataagtc cgaaaaattt
     1801 ctctggttcc ttattctgaa agtgaaacag caagagttga tagagctgat agtggtgttt
     1861 caagtcttgt gaatagctca aaagcttgtc taaaatctct ttattggtta aatgcatacg
     1921 aaaagtaggg cgataaaaat gtttatcgct gagtttacga ctatcctgtt gaatgagttt
     1981 ccagtagcgc ttgatagcct tgtattcatg ggattttcga tgaaactgat tcatgatttg
     2041 aacacgcaca cgactcatag cacggctaag atgttgtaca atgtgaaagc gatcaagaac
     2101 gattttagca ttcgggagtg aaacagtctg ggagactgtt tcagcctgag cctagaaatt
     2161 tgaaagcgaa gctgtttagc caagtcatag taagggctaa acatatccat agtaatgatt
     2221 ttgacgcgac atcggacagc tctatcgtag tgaagaaagt gatttcgaat gatagcttgt
     2281 gttctaccct caagaacagt gatgatattg agattgttaa aatcttgcgc aatgaagctc
     2341 atctttccct ttgtaaaagc atactcatcc caagacataa tctcaggaag acaagaaaaa
     2401 tcatgtttaa agtgaaaatc attgagctta cgaataacag ttgaagttga aatggccagc
     2461 tgatgagcaa tatcggtcat agaaatcttc tcaatcaact tttgcgcaat tttttggttg
     2521 atgatacgag ggatttggtg attcttcttg acgatagaag tttcagcgac catcattttt
     2581 gaacagtgat agcacttgaa acggcgtttt ctaaggagaa ttctagtagg cataccagtc
     2641 gtttcaagat aaggaatttt agaaggtttt tgaaagtcat atttcttcaa ttggtttccg
     2701 cactcagggc aagatggtgc gtcgtagtcc agtttggcga tgatttcttt gtgtgaatcc
     2761 ctattgacga catctataat ttggatattt gtgtctttga tatcgagtag ttttgtgata
     2821 aaatgtaatt gttccatatg aatctttcta atgagttgtt tgatcgcttt tcattataga
     2881 tcttatggga ctttttttct acacaaaaat aggctccata atatccatag gggatttacc
     2941 cactacaaat attatagagc cttatattat aattgtgtta ttttacttcc aactattgag
     3001 agaaatttcg ccactattta gccagatttc ttttccgtta tcacattgaa ctaaaagttt
     3061 tccattttct gagatgtctt tagcaagtcc cttgtagtct ttttgctgta gtgtgaaagt
     3121 gacttctttt cctagaatga atgactgttt tttgtatagg tataatagct cttctgctgg
     3181 tgtttcgaag aaagcacgcc agatttctat gatcaattca ttccttgtta taggagctgt
     3241 agctttaaat aagctggcag ctttttcttt taattcctga gggaagtctt taatagtgaa
     3301 attgatacct actccaataa tgatatctgt gactaagcca gtttctacag aggtcattgc
     3361 ttcagtaagg attcctccaa ttttatgatt gtttagatag atatcattga cccattttat
     3421 gtcgacatct attaaagtta ggttcttaat agctttgtag acagctccag ctacaagtag
     3481 tgtgtaggat ggtaatttgt cataggggag atttggttta agatggagtg tcatataaat
     3541 accaccttgt ggtgagtaga aggaacgttg aaaacgtcct cggcctgctg tttgatagga
     3601 agctagatag agggtatttg cttcatggcc taaatcaatt gcttcttttg catctagttg
     3661 tgttgatttt gtttcgggtt taaagctgac tttaattgga agattttctt ctagaatctc
     3721 tggaagaata aggtcaccat tcattagttt atatcctcta tttttgatac tatcaatttc
     3781 aatgccttct tgttctagtc gcttgatagc tttccaaatt gatgttcggc ttagggatag
     3841 tttttctgcg attttttctc cgctgatata gtcggtttct ttagatagga tttggtagac
     3901 agcttggtag gatttcataa tgttgccttt ctcactagtt ggtattgaga gtattctttt
     3961 cttgtatgac ttggagtctg attaaagtat tgtttataag ctttcgaaaa atggagtgga
     4021 tctgaaaaac ctaccgagta tgcaattacc ttgatggact cttgggtatt ttcgagaagt
     4081 tgtctagctc ggtgcattcg aacgtagagt aggtattctt tgggtgataa ggtattaaat
     4141 tctttgaata cgcttgataa gtagcttctg tgaacggata gttcttttgc taaatcttga
     4201 attgtaagtg attgaggata gtggctatca attaatcgtt tgcattcaag atagagttgg
     4261 tgggttgatg aaatattctt ttttttctga ttgggagcaa tagttcccag atgaaacatc
     4321 agttcatgaa gttgtcccat gatatggagt tgagctaatt cacttgattt tgtaatctga
     4381 gcgaagcgga caatgtctga gatgagtttt gcagtagtct gggtatgaca agtttcagat
     4441 tggatgagat aggattgatc agaaatttga gaaagagcaa aataatcagg ggatttccct
     4501 ccagtgattc ctaaccagta gtaggcccaa ggttctttac tatctgcttg ataaaaggtt
     4561 agttcctctg gttttaatag aaagaaatct ccttctttta aataaacaat tttatccttg
     4621 taatgaaatt ttccttgtcc tttagtaatg taatgtagga cgtatgtatc acgaatggct
     4681 ggaccaaaag agtaattagg tgtgcattcc tcatatccat aaaagcttag ggcaaggtcg
     4741 attgttccag tctggtattc tgaaaaaact aacatgtgct acctcctacc taacatttta
     4801 ccatattctt gagacatttt tctattttgg aaagcgattt caggtgataa aatataatca
     4861 ataaagtgat gaggtgaagt aaatgggagt taggatagag aataatctat tttatgttga
     4921 gagtaaaaat ctaagtttga ttattgaaaa tcgaaatggc tacttacttt tgaaacattt
     4981 aggaaagact attaagaact ataaaggttc caatagtgtt tatgaacgag accatgcctt
     5041 ttcaggaaat ccaacggcta ctaatcgaac ctttagttta gatactcagc gacagatttt
     5101 tggacaacat ggcttaggag attttaggaa accaactata caggttcagc atagtgtaac
     5161 tgaagtaaca gactttcgat ttgtagaagc aaagatttta aaaggtcaga atggtccaca
     5221 gggcttacct tctccacata gcatggacga tacagagact cttgtcttaa tgttagaaga
     5281 ttctaaggct caacttagtc tgactttgta ttatactact tttaataatg atgcgactat
     5341 tactagctac agtaaattag ataataatag taatcaggaa gttgtcatcc ataaagattt
     5401 ttcttttatg gctgattttc cagctgcaga ttatgaaata gcaactctgc agggtgctta
     5461 tgctcgtgaa aagactgtta gacgtcaaca ggtagaacaa ggaatctttt cgattagttc
     5521 aaaccgaggt gcttctggtc atgctcaaac accagctctt ctactatgcg aacaaggagt
     5581 cacagaggat gctgggaatg tgtttgctat tcaactaatg tatagtggca actttgaagc
     5641 ttttgttcaa aaaaatcaat tgaatgaagt tcgggtggct attggcatta atccagaaaa
     5701 cttttcttgg aagttagccc ctgaggaata ctttgaaaca ccggtagctt tagtgactca
     5761 ttcagatcag ggattaactg gtattagtca tgaaagtcag aattttgtac tgaagcacat
     5821 tatgctaagt gaattttcta aaaaagaacg tccaattcta atcaataact gggaagctac
     5881 ttactttgac tttcagagag aaaaactgtt agagttagca gatgaagcta agaaagttgg
     5941 cattgaactt tttgtattag atgatggttg gtttggcaat cgttttgatg ataatcgtgc
     6001 tttaggtgat tgggttgtta atgaggaaaa actgggtgga agtctagaaa gtctgatttc
     6061 agctatccat gaaagaggtt tgcagtttgg actttggtta gaacccgaaa tgatttctgt
     6121 agatagtgat ttgtatcgtc aacatcctga ctgggctatt caggttcctg attatgagca
     6181 tacttattct cggaatcaat tagtacttaa tcttgccaat cctcaggtag tagaatactt
     6241 gaaaagtgtc ttagatcaac tcctatctta tcatgagatt gattacatta aatgggatat
     6301 gaaccgcaat atcactaagc tagggaatgg attaacttat ctagagacac agatgcaatc
     6361 tcatcagtac atgctggggc tttacgaact cgtttcttat ctgacagaga agcacagcca
     6421 tattctcttt gagtcctgct ctggtggtgg tggacgaaat gatcttggta tgatacgcta
     6481 tttcccacaa gtctgggcta gtgataatac tgatgccatt gcacgtttac caattcaata
     6541 cggttcatcc tatctctatc caaccatttc tatgggggct catgtgtcag cagtaccgaa
     6601 tcatcagatg ggacgaatga caccattaga aacacgtggc catgtagcaa tgatgggaaa
     6661 tttgggctat gagcttgatt tgacaaattt atcagatgaa gagaaagcta cgattgctaa
     6721 tcaggtgaac ttgtataaag aattacgacc agtagttcag ttaggacagc agtatagact
     6781 aattaatcct gatactgcat ccaatgaagc agctgtacaa tttaattacg gaaatcaaac
     6841 gattgtaacc tacgttcgcg ttttatctgt tgtagagacc atggaaacaa ctttaaaatt
     6901 aaaagatttg gatgaagagg gactatataa attacaggaa aatggcgaag tttactcagg
     6961 tgcagaacta atgtatgcgg gcttaactgt tatcttatcc caaggagatt ttttgagtag
     7021 acagtatatt tttagaaaac tatgatatgt actgacccca aaagttagat ttattctgtc
     7081 taacttttgg ggtgcagttc aataagggtg tataaattta taaaggaggc tttctaatgg
     7141 aatggtataa aaaaatcgga cttcttgcaa ctacaggttt agctttgttt gggctcggcg
     7201 cttgctccaa ctatggtaaa tctgcggatg gcacagtgac catcgagtat ttcaaccaga
     7261 aaaaagaaat gaccaaaacc ttggaagaaa tcactcgtga ttttgagaag gaaaacccta
     7321 agatcaaggt caaagtcgtc aatgtaccaa atgctggtga agtattgaag acacgcgttc
     7381 tcgcaggaga tgtgcctgat gtggtcaata tttacccaca gtccatcgaa ctgcaagaat
     7441 gggcaaaagc aggtgttttt gaagatttga gcaacaaaga ctacctgaaa cgcgtgaaaa
     7501 atgcctacgc tgaaaaatat gctgtaaacg aaaaagttta taacgttcct tttacagcta
     7561 atgcttatgg aatttactac aacaaagata aattcgaaga actgggcttg aaggttcctg
     7621 aaacctggga tgaatttgaa cagttagtca aagatatcgt tgctaaagga caaacatcat
     7681 ttggaattgc aggtgcagat gcttggacac tcaatggtta caatcaatta gcctttgcga
     7741 cagcaacagg tggaggaaaa gaagcaaatc aataccttcg ttattctcaa ccaaatgcca
     7801 ttaaattgtc ggatccgatt atgaaagatg atatcaaggt catggacatc cttcgcatca
     7861 atggctctaa gcaaaagaac tgggaaggtg ctggctatac cgatgttatc ggagccttcg
     7921 cacgtgggga tgtcctcatg acaccaaatg ggtcttgggc gatcacagcg attaatgaac
     7981 aaaaaccgaa ctttaagatt ggaaccttca tgattccagg aaaagaaaaa ggacaaagct
     8041 taaccgttgg tgcgggagac ttggcatggt ctatctcagc caccaccaaa catccaaaag
     8101 aagccaatgc ctttgtggaa tatatgaccc gtccagaagt catgcaaaaa tactacgatg
     8161 tggacggatc tccaacagcg atcgaagggg tcaaacaagc aggagaagat tcaccgcttg
     8221 ctggtatgac cgaatatgcc tttacggatc gtcacttggt ctggttgcaa caatactgga
     8281 ccagtgaagc agacttccat accttgacca tgaactatgt cttgaccggt gataaacaag
     8341 gcatggtcaa tgatttgaat gccttcttta acccgatgaa agcggatgtg gattaggagt
     8401 agagagacta tgaaaaaagt attacaaaaa tattgggcat gggcttttgt ggtcatcccc
     8461 ctcttgttac aagcaatttt cttctatgtg ccgatgtttc aaggagcctt ttacagtttt
     8521 accaactgga caggattgac ttacaactac aaatttgtcg gcttaaacaa ctttaagctc
     8581 ctcttcatgg atccaaaatt catgaatgcg attggcttta ccgcaatcat tacgattgcc
     8641 atggtggttg gtgagattgc actcgggatc ttcattgcgc gtgtcttgaa ctctaaaatc
     8701 aaaggccaaa ccttcttccg tgcttggttc ttcttcccag ctgttttatc tggtttgaca
     8761 gtggctttga tcttcaagca agtcttcaac tacggtcttc cagcgattgg gaatgccctt
     8821 catattgaat ttctccaaac cagtctttta gggactaagt ggggagcaat ctttgcggct
     8881 gtctttgtcc ttctttggca aggggtggct atgcccatca tcatcttcct agctggtttg
     8941 caatctattc caactgagat tacagaggca gcaaggattg atggtgcgac tagcaagcaa
     9001 gttttctgga acattgaatt gccttacttg ctaccaagtg tctctatggt ctttatccta
     9061 gccctaaaag gtgggctgac tgcctttgac caagtctttg ccatgaccgg tggtggtcca
     9121 aacaatgcca caacctcact tgggctcttg gtttataact atgcctttaa aaacaaccaa
     9181 ttcggttatg ccaatgccat tgccgtaatc ttgttcctct taattgtagt gatttcgatc
     9241 atccaattga gagtatctaa gaaatttgaa atttaagagg agaagcatga tgaaacaaga
     9301 tgaaacaaga tgaaagaaaa gccctgattg gcaaatacat tctattgatt ctaggatcgg
     9361 ttctgatttt agtgccgctc cttgctaccc tctttagttc cttcaaaccc actaaggata
     9421 ttgtagataa tttctttggc tttccaacca acttcacatg ggacaacttt agccgtctct
     9481 tagctgatgg gattggaggc tattattgga actctgtcgt catcactgtc ttgtctttac
     9541 ttgcagtaat gatctttatc cctatggcag cctactccat cgctcgcaat atgagtaaaa
     9601 gaaaagtctt taccatcatg tataccctct taatcctcgg aatcttcgta cctttccaag
     9661 tcatcatgat tccgattacg gttatgatga gtaaactcgg tttggctaat acctttggtt
     9721 tgatcttgct ctacttgacc tatgcgattc cacagaccct ctttctctat gttggctata
     9781 tcaaaatctc gattccagaa agtctggatg aagcagcaga gatcgatggg gctaatcaat
     9841 ttacaaccta tttccgcatc atcttcccaa tgatgaaacc gatgcatgcg acaaccatga
     9901 tcatcaatgc cctttggttc tggaatgact tcatgttgcc actccttgtc ttgaaccggg
     9961 attccaaaat gtggactctg cctttgttcc aatacaacta cgcaggccaa tatttcaacg
    10021 actacggacc aagctttgcc tcttacgtgg tcggcattat cagtatcacc attgtctatc
    10081 tcttcttcca acgccatatc atttcaggaa tgagcaacgg ggcagtgaag taatactcaa
    10141 tgaaaatcaa agagcaaact aggaagctag ccgcaggttg ctcaaaacac tgttttgagg
    10201 ttgtggatga aactgacgaa gtcagtaacc atacctacgg taaggtgaag ctgacgtggt
    10261 ttgaagagat tttcgaagag tataagaaga gctcatggaa tctatagtct ttgacacaga
    10321 ggaagagttc agcttgttga taattctatg tagaaaacaa gaaagtagta ctttgtttat
    10381 cacagtctat attagtacga gtttgatgat aaatagagat ttaaaatgaa tttgatttac
    10441 gaagccagat catatgagac ttggcttcaa ttagaaaaag gagagtaatg atgccgattc
    10501 aaaataaaac catgttgatt acctattctg atagccttgg aaataatctt aaagacttat
    10561 atgataattt ggaagagcat tttggagatg ctattggagg agttcacctt ttaccatttt
    10621 tcccatcaac aggtgatcgt ggatttgcgc cagttgacta cgacgaagtg gactcagctt
    10681 ttggtgattg ggaggatgtt aagcgtttag gtgagaaata ttatcttatg tttgatttta
    10741 tgattaatca tatttctcgt caatccaagt attataagga ctatcaagaa aaacatgaag
    10801 ccagtgaatt taaagctctc tttttaaact gggataagtt ttggccagaa aaccgtccga
    10861 cacagtctga tgtagattta atttacaagc gtaaggatcg tgcaccaaag caagagattg
    10921 tgtttgaaga tggttcagtg gaacatttgt ggaatacctt tggtgaggag cagattgatc
    10981 ttgatgtgac caaagaagta actatggaat ttatccgtaa gaccattcag cacttggcaa
    11041 gtaatgggtg tgatttgatt cgtctagatg cctttgctta tgcagtgaag aaattggata
    11101 ctaatgattt ctttgtggaa ccagatattt gggatttatt ggacaaagtt cgagatatcg
    11161 ctgctgagta tgggacagag cttttacctg agattcatga acactattcg attcagttta
    11221 aaatagcaga ccatgattac tatgtttatg attttgctct tccaatggtg acactttata
    11281 ctctttacag ttccagaaca gagcgtttgg ctaagtggtt aaagatgagc ccgatgaagc
    11341 aatttacgac gctagatacc catgatggga ttggagtagt agatgtcaag gatatcctga
    11401 ccgatgagga gattgactat gcttcaaatg aactctataa ggttggagcc aatgtcaaac
    11461 gtaagtactc tagtgccgag tataacaact tagatatcta ccaaatcaat tcaacctact
    11521 attcagcgct tggagatgat gatgtcaagt attttctcgc tcgtctaatt caagcttttg
    11581 ccccaggtat tcctcaggtt tactatgtgg gtctattagc aggcaagaat gacttgaaat
    11641 tattagaaga aactaaagaa ggtcgaaata ttaatcgtca ttactatagc aacgaggaaa
    11701 tagcaaaaga agtgcaacga cctgttgtga aggcccttct caatctattt tctttccgta
    11761 accgttcaga agcctttgat ctagaaggga ctactgagat agagacacca acagctcaca
    11821 gcattgtaat caaacgtcaa aataaagata agtccgtaac agcagtagta gaaattgatt
    11881 tgcaaaatca gacttatcgg gtaattgaga atggagttga agtatcattt tgaagccttg
    11941 atatggtgga taaaataggg tttttatttt ggaaaacgtt tcctttgttt tcaaattgct
    12001 aaaaaagtgg tacaatatag gatagcttac tattatctga atcagctgat ttggagagaa
    12061 aggattcatt ttgaaatcaa taggctttat tgaaaagctg aaggggttgt ctagtaaaga
    12121 gctgatttta ttgggaatta tcctaagtat ctttttaccc ttttatcttt ttgtagttgt
    12181 actctgttta tatattatca gtttgatttt tacaggagac atgaaaagta ttcttcagaa
    12241 aatgggggag catccgatgc tgcttctttt tcttagctat agtactgtta tatccattct
    12301 tgcacaaaat tggatgggtc ttgtggcttc agtaggaatg tttctattta ctattttctt
    12361 tttgcactat cagtcgattt tatcccataa attctttcga ttgattttgc agttcgtctt
    12421 gtttggtagt gtcttgtcag ctgcttttgc cagtttagaa catttccaaa ttgtgaagaa
    12481 atttaactat gcttttcttt cacccaatat gcaggtgtgg catcagaacc gggcagaagt
    12541 gaccttcttt aatcctaatt attatggaat tatttgttgt ttctgtatta tgattgcttt
    12601 ctatctgttt acaacgacca agttgaattg gttgaaagta ttctgtgtga ttgcaggctt
    12661 tgtgaatctc tttggtttga actttactca aaatcgaact gcctttcctg ctattatcgc
    12721 tggagcaatt atctatctct ttacgactat taaaaactgg aaggcctttt ggcttagtat
    12781 tggggtcttc gcgattggtt tgagtttcct cttttctagt gatttgggag ttcgaatggg
    12841 tactttagac tcttctatgg aagaacgcat ttctatctgg gatgctggga tggccttgtt
    12901 taagcaaaat cctttttggg gtgaagggcc attgacctat atgcactctt atcctcggat
    12961 acatgctcct tatcatgaac atgcccacag tctttatatt gatacgattc tgagttacgg
    13021 aattgtgggt accattttat tagttttgtc ttctgttgct cctgttcgct tgatgatgga
    13081 tatgagtcag gagtcgggga aacgtccgat tatcggcctt tatctatctt tccttacagt
    13141 ggttgctgtg cacggaattt ttgacttggc tctcttctgg attcagtcag gctttatttt
    13201 cttgctagtt atgtgcagta ttccattgga gcatcgaatg ttggtatcgg acatgacgga
    13261 ttaagtttta taagtttgaa atcttctacc ttgggtagga gattttttta tacgatgggc
    13321 atgtcgtgca tctgaggtgt aagtcctctg tagggatcca ctaccggtga atacaatagc
    13381 gctccccaag cctgactatc gtgaggtagc ggattaaaat ggtctgggga tagatcgttt
    13441 taagtctgac gcaggaaata agaattgtca gagaaagcaa tagtgaaatc gtaggctatg
    13501 aatagaaacg tgatagcgag gagcatatag tggacaaggt agcgagaaat tttaaagtat
    13561 aaaagatagt cttaatctat atgtgtaaat cacgaaagta attgaattcg gaataaggtt
    13621 ggtgtgaaaa gacatagtaa actgaatctt gaatactaga atgatacttc tacaatattg
    13681 ttataattta atttgaattc caaaatcaca ttgttccgtc cgtatttcat tttactgtat
    13741 gtcttcctaa gctccaaaat ttctgtgtca aatttcctat tttcactgta gtctttgaca
    13801 cttcgaacga caatttgaat catatattca aaaaaaatga aaaatttgtg ccaacaagcc
    13861 taaatattct gaaaatttgt ttgattttta atggataatg tgatataatg gttgtcaatc
    13921 tataattcac ataaacagag gagtagaaaa tgaaaaaaaa tcgtgtattt gctacagcag
    13981 gtcttgtttt attagcagca ggtgtacttg cagcatgcag ttcttcaaaa tcatctgatt
    14041 catcagcccc taaagcttat ggctatgttt atacagcaga cccagaaacc ttggactacc
    14101 tgatttcaag taaaaatagt acaacagtag tgacttcaaa tgggattgat ggtttattca
    14161 ctaacgataa ttacggtaat cttgctcctg cagttgcaga ggattgggaa gtctctaagg
    14221 atggtttgac ctacacttat aagattcgta aaggggttaa atggtttacc tctgatggag
    14281 aagaatatgc agaggtgacg gctaaagatt tcgtgaacgg tttaaaacac gcagcagata
    14341 aaaaatcaga agctatgtat ttagctgaaa attcggttaa aggcttggca gattatctat
    14401 caggaacttc aacagatttt tcaacagttg gtgtcaaggc ggttgatgat tatacgttac
    14461 aatacacttt gaaccagcct gaaccgttct ggaactctaa gttgacctat tctattttct
    14521 ggcctctgaa tgaagaattc gaaacatcaa aaggaagcga ttttgctaaa ccaacagatc
    14581 cgacatcctt gctttataat ggtccattct tgttgaaagg gttgactgca aaatcttctg
    14641 tagagtttgt aaaaaatgag caatattggg ataaagaaaa tgtccaccta gatactatca
    14701 atctagctta ctatgatgga tcagatcagg agtcgctaga gcgtaacttc actagtggag
    14761 cttatagtta tgcccgtctt taccctacca gctccaacta ttctaaggtt gcagaagaat
    14821 acaaggacaa tatctattac acacaatcag gctctgggat tgctggtctg ggtgtgaata
    14881 ttgatcgcca aagttacaac tatacttcta aaactacaga ttcagagaaa gtagctacta
    14941 agaaggcatt gcttaacaaa gatttccgtc aagccttgaa ttttgctctt gatcgctcag
    15001 cttactcagc tcaaatcaat ggtaaagatg gagcagcttt agcagttcgt aatttatttg
    15061 taaaaccaga ctttgtttca gctggtgaga agacctttgg tgatttagtc gctgctcaac
    15121 ttcctgctta tggtgatgag tggaaaggtg tgaatttagc tgatgggcag gatggtttat
    15181 tcaatgctga caaggccaag gcagagtttg cgaaagctaa gaaagcttta gaagcagacg
    15241 gcgttcagtt tcctattcat ctggacgttc cagtagacca agcatcaaaa aactatatat
    15301 ctcgtattca gtcctttaaa caatctgtag aaacagttct tggtgttgaa aatgtcgttg
    15361 ttgatattca acaaatgaca agtgatgaat tccttaatat tacttactat gctgccaatg
    15421 cttcatctga ggattgggat gtatcgggag gagtttcatg ggggccagac tatcaagacc
    15481 catctactta cctggatatt ttaaaaacaa ctagcagtga aactacaaaa acatatttag
    15541 gatttgataa tccaaatagc ccttcagtag ttcaagttgg tttgaaagaa tacgataaat
    15601 tagttgatga agctgccaaa gagacaagcg acttgaatgt ccgttatgaa aaatatgcag
    15661 cggctcaagc atggttgaca gatagttcac tctttattcc tgctatggct tcttctggtg
    15721 cagcaccagt gctttcacga attgttccat ttactggagc ttctgcgcaa acaggctcta
    15781 aggggtcaga tgtttacttc aaatatttga aattacaaga taaagcggtg actaaggaag
    15841 agtatgaaaa agctcgtgaa aaatggttga aagaaaaagc tgaatcaaat gagaaagctc
    15901 aaaaagaatt ggcaagtcat gtgaagtaaa taatttctaa tagaactttc tctccatgag
    15961 gagaaggttc ttttgggatt tttaaaggaa ataatatgaa aaaatatatt tttatgcgtg
    16021 ttttgcggtc attggtttcg attttcttag taacgacttt gacctacacg attatctata
    16081 ccttggttcc tcgaaaattg attttcaagc aggatcctaa ctataataaa attgcgacaa
    16141 cggctgataa acgtgataac tatgaaaata ctgtgtttga gcgtatgggc tacattgagt
    16201 attacgatac taaagagttg caagaaaagg caagtagcat ggattcttct gtaacagtag
    16261 aagcaaatgc gaccaataaa gctatttatg aaaagtacat caatcaatta ggtcatggtt
    16321 ggactttggg agaatttact gaaagtggtc aattctatgc tactcgtgaa attccaattt
    16381 ttgaacgtgt ttttcacttc tatgctaact tgattgacat tgaccataca aataaaatcc
    16441 aagaccctga aaatccagac ttgaaacgct accttcgttt tgaaaacgat ccagctatcg
    16501 gatggtcatt ggtcggttca ggaactaaac ataaatatct cttgtacttt aacagtcagt
    16561 tcccatttgt tcatcaaaac tttgtgaact tgaatttagg tgactcttac ccaacctatg
    16621 ctaatacacc agttcttcag gttattactc aaggtcaagg acaaaccaaa actgcccaag
    16681 ttcagttccc aacaggtaag aaaacgtctt ctgtaaatat ttactcaaga acctacaagt
    16741 cacctagtca ggctgactct cgtgaagtag ctagctatgg gaaagatgat ccttatacag
    16801 cgactgaaag taattaccaa tatccatcta tgattgtcag ctctgctatt actggtttga
    16861 ttggtttggt tcttgcctat gctcttgccg tgccacttgg ttcagccatg gctcgtttca
    16921 agaacacttg gattgatagc ctctcaacag gggctttgac cttcttgctt gctcttccaa
    16981 cgattgcctt ggtttacatc gttcgattga ttggatcatc tatttccctt ccagattcat
    17041 tccctatctt gggagctgga gattggcgtt cttacgtttt accagcagtc atccttggtt
    17101 tgttgggtgc tcctggtaca gccatttgga ttcgtcgtta catgattgac ttgcaatctc
    17161 aagactttgt tcgtttcgct cgtgcaaaag gtttgtctga aaaagaaatt tcaaacaaac
    17221 acatctttaa aaatgccatg gttccgctgg tttcaggaat tcctggtgcc attattgggg
    17281 ttatcggtgg tgcaaccctt actgaaacag tcttcgcctt cccaggtatg ggtaaaatgt
    17341 tgattgactc tgtaaaagca tctaataact ctatggtcgt tggtcttgtc ttcatcttta
    17401 catgtatttc tatcttctca cgtcttttgg gagatatttg gatgactatt attgacccac
    17461 gtattaaatt gactgagaaa ggaggcaaat aatgtctaca atcgataaag aaaaatttca
    17521 gtttgtaaaa cgtgacgatt ttgcctctga aactattgat gcgccagcat attcttactg
    17581 gaaatcagtg tttaaacaat ttatgaagaa aaaatcaact gtagtcatgt tgggaatctt
    17641 ggtagccatc attttgataa gtttcatcta cccaatgttt tctaagtttg atttcaatga
    17701 tgtcagcaag gtaaacgact ttagtgttcg ttatatcaag ccaaatgcgg agcattggtt
    17761 cggtactgac agtaacggta aatcgctctt tgacggtgtc tggttcggag ctcgtaactc
    17821 catcctcatt tctgtgattg cgacagtgat taacttggtt atcggtgttt ttgtcggtgg
    17881 tatttggggt atttcaaaat cagttgaccg tgtcatgatg gaagtttaca acgtcatctc
    17941 aaacatccca cctcttttga ttgttattgt cttgacttac tcaatcggag ctggattctg
    18001 gaatctgatt tttgccatga gcgtaacaac atggattggt attgccttca tgatccgtgt
    18061 gcaaatcttg cgctatcgtg acttggaata caacttggcg tcacgtactt tgggaacacc
    18121 aaccttgaag attgttgcca aaaatatcat gcctcaattg gtatctgtta ttgtgacaac
    18181 catgactcaa atgcttccaa gctttatctc atacgaagcc ttcttgtctt tcttcggtct
    18241 tggattaccg attacagtgc caagtttggg tcgtttgatt tcggattatt cacaaaacgt
    18301 aacaaccaat gcttacttgt tctggattcc attgacaacc cttgtcttgg tatccttgtc
    18361 ccttttcgta gttggtcaaa acttagcgga tgctagtgat ccacgtacac atagatagga
    18421 gtagaaatga caaaagaaaa aaatgtaatt ttgactgctc gcgatattgt cgtggaattt
    18481 gacgttcgtg acaaagtatt gacagccatt cgcggcgttt cccttgaact agtcgaagga
    18541 gaagtattag ccttggtagg tgagtcagga tcaggtaaat ctgttttgac aaagaccttc
    18601 acaggtatgc tcgaagaaaa tggtcgcatt gcccaaggta gtattgacta ccgtggtcag
    18661 gacttgacag ctttatcttc tcacaaggat tgggaacaaa ttcgtggtgc taagattgcg
    18721 actatcttcc aggacccaat gactagtttg gaccccatta aaacaattgg tagtcagatt
    18781 acagaagtta ttgtaaaaca ccaaggaaaa acagctaaag aagcgaaaga attggccatt
    18841 gactacatga ataaggttgg cattccagac gcagatagac gttttaatga atacccattc
    18901 caatattctg gaggaatgcg tcaacgtatc gttattgcga ttgcccttgc ctgccgacct
    18961 gatgtcttga tctgtgatga gccaacaact gccttggatg taactattca agctcagatt
    19021 attgatttgc taaaatcttt acaaaacgag tatcatttca caacaatctt tattacccac
    19081 gaccttggtg tggtggcaag tattgcggat aaggtagcgg ttatgtatgc aggagaaatc
    19141 gttgagtatg gaacggttga ggaagtcttc tatgaccctc gccatccata tacatggagt
    19201 ctcttgtcta gcttgcctca gcttgctgat gataaagggg aactttactc aatcccagga
    19261 acacctccgt cactttatac tgacctgaaa ggggatgctt ttgctttgcg ttctgactac
    19321 gcaatgcaga ttgacttcga acaaaaagct cctcaattct cagtatcaaa gacacattgg
    19381 gctaaaactt ggcttcttca tgaggatgct ccaaaagtag aaaaaccagc tgtgattgca
    19441 aatctccatg ataagatccg tgaaaaaatg ggatttgccc atctggctga ctaggaggaa
    19501 ggaaatgtct gaaaaattag tagaaatcaa agatttagaa atttccttcg gtgaaggaag
    19561 taagaagttt gtcgcggtta aaaatgctaa cttctttatc aacaagggag aaactttctc
    19621 gcttgtaggt gagtccggta gtgggaaaac aactattggt cgtgctatca tcggtctaaa
    19681 tgatacaagt aatggagata tcatttttga tggtcaaaag attaatggta agaaatcgcg
    19741 tgaacaagct gcggaattga ttcgtcgaat ccagatgatt ttccaagacc ctgccgcaag
    19801 tttgaatgaa cgtgcgactg ttgattatat tatttctgaa ggtctttaca atcaccgttt
    19861 atttaaggat gaagaagaac gtaaagagaa agttcaaaat attatccgtg aagtaggtct
    19921 tcttgctgag cacttgactc gttaccctca tgaattctca ggcggtcaac gtcaacgtat
    19981 cggtattgcc cgtgccttgg tcatgcaacc agactttgtt attgcagatg agccaatttc
    20041 agccttggac gtttctgtac gtgcccaagt cttgaacttg ctcaaaaaat tccaaaaaga
    20101 gctcggcctg acctatctct tcatcgccca tgacttgtcg gttgttcgct ttatttcaga
    20161 tcgtatcgca gttatttaca agggtgttat tgtagaggtt gcagaaacag aagaattgtt
    20221 taacaatcca attcacccat atactcaagc cttgctttca gcggtaccaa tcccagatcc
    20281 aatcttggaa cgtaagaagg tcttgaaggt ttacgaccca agtcaacacg actatgagac
    20341 tgataagcca tctatggtag aaatccgtcc aggtcactat gtttgggcga accaagccga
    20401 attggcacgt tatcaaaaag gactaaacta gtaatggttt tataatttcc atgtcaattt
    20461 ttatggaaat tataaaactt tttttgttgg actgatttga aaaactttga aagcttcctg
    20521 aaagaatttt tgaaaaattt taaaaattat gaaatgttat tgacaggtga tgaaaaaggt
    20581 ggtaggacag gaagcatcaa aaaagaaagc agaaaaagaa atgaataaga gacaagccgt
    20641 aactatgaat caaaactttt actttagcta ctttagatag tgtttgtaga catgtcacca
    20701 tggatgcaaa cagttcaagc aatttgtttg tatctatgtg gctaagattt ttgattgtgg
    20761 tccatataga tgaatatcta aatggactag ctaagttgta acttgttagg ttatttcaag
    20821 tatccgttta gatagtatct aggcggtttt ttgttttatc ttttctgaga aggagtttca
    20881 ttatgaaagt tgttcgaaaa tcactagccc cctcttggta gtggggctcc tcttgacttc
    20941 tctgatcagt ttgcatcagt tgaaggcaga taagaaaaag atgtctttcg tatcggtatt
    21001 tcgcaattta ttacccacca gtccttatac gctactagag aaggatttgt ggatgagctg
    21061 gccaaacaag gctatgttga gggggaaaat attgagattg atttgcaaaa tgcacaggga
    21121 gaacaaagaa atctaaaaac gatttcccag caactagcag aatccagcga tgtcgttcta
    21181 gccatcgcaa ggccttctgc tcagagcttg gccaatacga cgcaaacgac accagttatc
    21241 ttttcagctg taacagaccc agtcagtgcc aagttggttg agtcaagaga acatcctggg
    21301 ggcaatgtaa ctgggacaag cgatcagtca tcagatgcca tttcaaccca aatcaatttg
    21361 ataaagaaag tgttgccaaa ggctaaaacg attggaatcc tctatactca gagcgagccc
    21421 aattcggttg ttcaaaagga tgaagctaag cgacttctga aagaaaaagg ctttaccgtt
    21481 gttgaaaaaa caatcttgga cagtaataac gtcaaggcgg cagcagagag tttgatggca
    21541 gaggtggata tggtttttgt cccaactgat aatatcattt cgttaaccat ggaaacagtt
    21601 aagcaggttt ctattaaaca caaggttcca gtattcggtg gttcaacaga aatgattgct
    21661 gttggtggct tgtataacta cggaaccaat tatgaagaat tggtacgtca gacagctcgc
    21721 atgctgattc gtgttttaaa aggtgagaaa ccagaaaata tagcagttga gttgcctgaa
    21781 aaactggaat tgcataccaa tcaagaaatg gcagatgcat tgggaattga tattagtaag
    21841 ttagaaggca aggaataagg aggattaaga tgaattttgt gttatctagt ttatcagaag
    21901 gtttgttgtg gtcgattgtg gcgattgggg tctacttgac tttccgtatt ttggatattg
    21961 cggatatgac tgctgaggga gcctttcctc tgggggcagc agtcgttgta tcacagatac
    22021 aggcaggggc aaatccttgg cttgcgactt tacttgcttt gctggcaggt atggtagcag
    22081 gtcttgtatc aggaatgctc cacaccaaga tgaaaatccc agctctcttg acagggattg
    22141 tgaccttgac agggctctat tcaatcaata ttaaaatcat gggcagtgta cccaatcttt
    22201 ccttgggaga ttctgcaacc gtctttaaac agttggcgag cttgggtctg acaaatgaag
    22261 gaactgtttt ctcacttagt ttggcctgtt ttttacttgt ttgtttggtc ttgacccttt
    22321 tgatgaaaac agagattggc ttggtcttgc gttcgactgg ggataatatc ccgatgagtg
    22381 aggccaatgg agtcaatgta gacaccatga agattgttgg ttacatgatt tcaaacggtt
    22441 tgattgctct atgtggttcc ttgtttgccc aaaatgatgg attttcagat gtgacttctg
    22501 ggacaggaac cattgttgtt ggtttgagct cggtgattat tgcggaagtc ttgatacacg
    22561 acttgaccat tggaggccgc ttattatcca tcggaatcgg tgctattgtt taccgtttga
    22621 ttattttaaa tatctatgaa attccaaatc tagatcaaaa cttggtacgt ctctttaatg
    22681 caatcttgct cgctttggtt ttatttgcac cagaattgca aaagagatta aagattcgtg
    22741 gtctgaaatt gagaaatgaa taggaggaga aagttatgac aagtttgtta acacttgaaa
    22801 atattcacaa gacatttgaa gcagggacgg tcaatgagaa ccatgtcctc aaaggattag
    22861 atttagaggt tgaagaggga gattttatct ctgtgattgg tggaaatgga gcaggaaaat
    22921 ccactttgat gaatatcttg gctggcaatc tatcggtgga cgaaggggac cttctactgg
    22981 cagggaaatc cattaaaaat ctgagtgtca gaaagagagc caaggatatt gcccgtgttt
    23041 ttcaagatcc taagatggga acagcttctc gtttgacgat tgaggagaat atggctattg
    23101 ccttgagacg cgggcagaag agagggcttg gttggggcgt gaaggagaag gatagaatcc
    23161 agttccaaga ggccttgaag gagttgaata ttggtcttga aaaccgctta aaagtagata
    23221 ctcaatatct ctcaggagga caaagacagg ctttgactct agtcatgaca gatctgatga
    23281 aaccaaaact tttacttttg gatgaacata ctgcggcact tgacccgaaa accagtcaaa
    23341 tggtgatgga cttgacgcaa aagattgtgg agcaccatca gtggacgact ttgatgatta
    23401 cccatgatat gaatcatgcg attgagtacg gcaatcgtct cattatgctc tatcaaggca
    23461 agatagtggt ggatgtcaag ggagaagaga aaaagcatct gacagttgaa gaccttatgc
    23521 atctcttcca gaaaaatagt ggccaaagtc tggtcagtga tgaattagtt ttgggataaa
    23581 gaaaaaggct gagatctggt gtctcagtct tttatttctt gcgttttgca aaatctacaa
    23641 atctaaattt ctctaactta tggcgacttt cggtaaactg aaattggcgt ccgtcttgga
    23701 gatagacttt tgatttaatc gaaacgacat aagggtcttt gccaatgtcc atgagaatct
    23761 tgtctcggtc gcttgagtgg tcaatggtga tttccttctg agcataatca ataaggagtt
    23821 tgaggccatt ttctatataa gaatagatag actgctcagc aatttggcga gtgagatttg
    23881 gaattagttc catatccaga tagtccgtat ccagaacgga taccagatca tccaccacac
    23941 gctggcggac caccttccaa accatccgaa actctgggaa accggttatc agtgaggatt
    24001 ttttatcaat aataatcttg tccagactga ccacgttggt tttagagcgc agtccaagtt
    24061 ctttaactag ttcttggtag ctggttaggt tggatacagg gaaattgacg gtttcttctt
    24121 tgacgacttg agaaccttgc tctcttatct ttttgatcaa tccttcctct tggaggagag
    24181 acagggcctt tcggacggta tcacgactca cttgatattg ctccataagg tcgtgctcgc
    24241 taggaaggaa atctccgaca gcgtaagtct cgttttgaat ggtttcttgg atttgcttaa
    24301 ataattgttg gtatttcttc attttgcctg ctttaatagg tttttagtct agtttaatga
    24361 acacctgtat ctattttacc atacaagtgc tagaaaattt acaaaaaaac acccttttta
    24421 taccaaacaa gttgcagaca agtttggtat cgtttacaat atacttatca aatcaaactt
    24481 gctttgacaa gtataaggag aatcaaatgg gaaaatttga acaagaagcc aaagatctgc
    24541 ttcaggcaat tggaggcaaa gaaaatgtga ctgccgtaac tcactgtgcg acacggatgc
    24601 gctttgtttt aggagatgat aagaaggcta atgttaaagc tatcgagtca attccagctg
    24661 ttaaaggaac ttttacaaat gcaggtcaat ttcaggtaat cattggaaat gacgtgccca
    24721 tcttttataa tgattttaca gccgtttcag gtattgaggg tgtttccaaa gaagcagcca
    24781 agtctgcagc taagagtaat caaaacgtgg tccaacgtgt tatgaccact ctggcggaga
    24841 tttttactcc gattattcca gccttgatag tcggaggatt gatcctcggt ttccgtaatg
    24901 tcttggaagg tgtccattgg tcgatgttgg atggcaagac catcacagaa tcctctcagt
    24961 tttgggcagg tgtcaatcac ttcctctggt tgcctggtga agctatcttc cagttcttac
    25021 cagtagggat tacttggtct gtttctcgta agatgggaac cagccaaatt ttgggaattg
    25081 ttctcggaat ctgtttggta tcgcctcagt tgctcaatgc ctatgcggtt gcttcaacgc
    25141 cagcagctga tatcgcggca aactgggttt ggaattttgg ctattttact gttaatcgta
    25201 tcggttacca agcccaagtt atcccagcct tgcttgcagg tttgagtctg tcttatcttg
    25261 aaatcttctg gcgcaagcat atcccagaag tcatttctat gatttttgta cctttcttgt
    25321 cattgattcc agccttgatt ttggctcata ctgttttggg accaatcggt tggacaattg
    25381 gacaaggact ttcatcagtt gtcttggcag gtttaactgg tccagttaaa gggctcttcg
    25441 gtgcaatttt tggtgccctc tacgctccat ttgtcatcac aggtctgcac catatgacca
    25501 atgccattga tacacaattg attgcggatg ctggtggcac tgccctatgg ccaatgattg
    25561 ctctttctaa tattgctcaa ggctcagccg tgtttgccta ttatttcatg catcgccatg
    25621 atgagcgtga ggctcaggtt tcacttcctg caaccatttc agcctatctc ggtgttacag
    25681 aaccagctct ttttggggtt aacgtaaaat atatttatcc atttgttgct gggatgactg
    25741 gttcagccct tgcaggcatg ttatccgtta cttttaatgt aactgcggct tctattggta
    25801 tcggtggttt gccaggtatt ctctctattc aacctcaata catgctgcca tttgcaggaa
    25861 ctatgctagt tgcgattgtt gttccaatgc tcttgacttt cttcttccgc aaggctggtc
    25921 tctttacaaa aacagagggc gatacgaact tgcaggcaga attcgttgct caagaagaag
    25981 cagaatttgt gaaccatgaa ccagtagaac ttacttcggt agaaattatc agcccactaa
    26041 ctggccaagt gaaagaattg agtcaagcga cggatcctat ttttgcatca ggtgtcatgg
    26101 ggcaaggtct ggtcattgaa ccaagccaag gtgagttgac ctctccagtt aatgggacag
    26161 tgacggttct tttccctacc aagcatgcca tcggcattgt ctctgacgag ggagttgaat
    26221 tgctcatcca catcggtatg gatacagtag gtcttgatgg caaaggtttt gaaagtcttg
    26281 tagtccaagg agatcacgtt acagttggtc agcaactgat tcgttttgat atggatgtca
    26341 ttaaggctgc aggtctggtg acagaaactc ctgttatcat caccaaccaa gatgcttata
    26401 cagcgactat tcccggaact tatccgacaa cgattcaagc tggagcatct ctcatggtcg
    26461 ctacacgaat ctaatactct tcgaaaatct cttcaaacca cgtcagctct atctgcaacc
    26521 tcaaaacagt gttttgagca acctgtggct agcttcctag tttgctcttt gattttcatt
    26581 gagtataatt gaaatagcac aaatagggac ggaagactgc ttcctccctt ttatcagaaa
    26641 aggagaaaca gatgacactt gataaaggaa aagtagtcta tcaaatctat ccaaaatctt
    26701 acaaagacac cactgaaaac ggtattgggg atttccgtgg gattatcgaa aaaattccct
    26761 atttagccaa actaggcgtg gatatggtct ggctcaatcc attctatcca agccctcaac
    26821 gggataatgg ttacgatatt tcagattata tggcagtgga tcctcttttt ggtgatatgg
    26881 ctgattttga ggaaatggtg tgtgtcggta aagagcacaa gattgacttt atgctggaca
    26941 tggtacttaa tcattgttcg acagagcatg aatggtttca gaaagcccta gctggtgata
    27001 agtattatca agactttttc ttcatccaag accaaccaac agattggcag tctaagtttg
    27061 gtggttctgc atgggcgcct ttcggggata ctgggaaata ctatcttcac ctatttgatg
    27121 agacccaggc tgaccttaac tggcgcaatt ccaatgtccg taaggagctt ttcaaggttg
    27181 ttaatttctg gcgcgacaag ggtgtcaaag gtttccgatt tgatgtgatc aatttgatcg
    27241 gtaaggacga ggtttcagtg gactgtcctg aaaatgaagg gaagccagct tatacagaca
    27301 aacccatcgt tcataactat ttgcgtatga tgaaccaagc cacttttgga tctgacgata
    27361 gctttatgac agttggggaa atgtcttcta ccaccatgga aaactgtgtc ctctattcgt
    27421 cgcctgatcg tcaggaatta tccatgacct ttaattttca tcacctcaag gtggactata
    27481 aggatggaca aaagtggacc ttggctccct ttgattttga agagttgaag agtctttacc
    27541 atagttgggg taaggaaatg agtgataaag acggttggag tgccctcttt tggaacaatc
    27601 acgatcaacc acgtgccttg aaccgttttg tcgatattca aaacttccgc aaggaaggag
    27661 ccaccatgct agcggccagc attcacctgt cacgtgggac accttatatc tacatgggtg
    27721 aggaaatcgg gatgattgac ccagactatg attctatggc tgattatgtg gatgtcgaat
    27781 cgcttaatgc ctatcagatg ctcttagaag aaggaaagag tcagcaagaa gccttccaga
    27841 ttattcaagc taagtcgcgt gataattcac gcattcccat gcagtgggat gcttcggaaa
    27901 atgcaggatt ttcaacaggc actccttggt tgaaagctgg taaatcctat aaagacatca
    27961 atgtagaaaa tgaaatccag ggtccgattt ttaccttcta tcaagacttg attcgactgc
    28021 gtaaggaaat gccaatcatt tcagaaggaa gttacaaacc agcctttgaa gatagcaaac
    28081 aagtctacgc ttttgaacgc cagtttgagg atcaaaagtt actagtgctc aataactttt
    28141 atgctaaaga agtggaaatc gacttgccag cagtctacca aaatggacag attttgattt
    28201 caaactatga agatgcagaa gtgtctgaga aaattctact caaaccctat caaacactgg
    28261 ctatttatgt aaattaatac tcttcgaaaa tctcttcaaa ccatgtcagt tttatctgca
    28321 acctcaaagc ggtgctttga gcaacctgtg gctagcttcc tagtttgctc tttgattttc
    28381 attgagtata aacttagcaa ggagacctct ttttcagaaa agcagggttc tttttgctgt
    28441 ctattccatc cttgaaagtg tagaacaaac tggtcagggt ggctagtttg tggtataatg
    28501 aaagggactc aaaaagaaac aggagaaaaa tgatggattt acttttagca attgtattga
    28561 ttgtgctagc ttttctagga ggagctcttg gaggaatgta cttggttcgt aagcaaatcg
    28621 aaaaagaatt tgctgacaac ccacgtttga atgctgaagc agttcgtact cttttgagtg
    28681 caaatggtca aaaaccaagc gaagctaagg tacaacaagt ttaccaccaa atcatccgcc
    28741 aacaaaaggc agcccttgct aacaataaaa agaaaaaata aataaggaaa agtctgggat
    28801 gaaagttcca gacttctcac tatgttggtt atggtttagg gatgagactt tttccttgca
    28861 ttctattgat atttgattat gattaagaga gaggtagttg acattctatc aagctgtcgg
    28921 tcagttcgtt cagtacaagg aatcataatg aacgatcaat cagaaaaaag actagaaaga
    28981 agactgtatg gataatcgac caattggttt tttggattcg ggtgtcgggg gcttgaccgt
    29041 tgtgcgcgag ctcatgcgcc agcttcccca tgaagaaatc gtctatattg gagattcggc
    29101 gcgggcgccc tatggccccc gtcctgctga gcaaattcgt gaatatactt ggcagctggt
    29161 caactttctc ttgaccaagg atgtcaaaat gattgtcatt gcttgtaaca ctgcgactgc
    29221 ggtcgtctgg gaagaaatca aggctcaact agatattcct gtcttgggtg taattttgcc
    29281 aggagcttcg gcagccatca agtccagtca aggtgggaaa atcggagtga ttggaacgcc
    29341 catgacggta caatcagaca tataccgtca gaaaatccat gatctggatc ccgacttaca
    29401 ggtggagagc ttggcctgtc ccaagtttgc tcccttggtt gagtcaggtg ccctgtcaac
    29461 cagtgttacc aagaaggtgg tctatgaaac cctgcgtccc ttggttggaa aggtggatag
    29521 cctgattttg ggctgtactc attatccact ccttcgccct attatccaaa atgtgatggg
    29581 gccaaaggtt cagctcatcg atagtggggc agagtgcgta cgggatatct cagtcttact
    29641 caattatttt gaaatcaatc gtggtcgcga tgctggacca ctccatcacc gtttttacac
    29701 aacagccagt agccaaagtt ttgcacaaat tggtgaagaa tggctggaaa aagagattca
    29761 tgtggagcat gtagaattat gacaaataaa atttatgaat ataaggatga ccaggactgg
    29821 tatgttgggt cttatagtat ttttggtggc gttaacagtt tgagcgacta taagacagat
    29881 tttcctctgt ttgaattctc caaaatattt ggagatgaag agtatggttt cccgctttca
    29941 gttactgttt tacgctatgg ttctacctac cgtttgttct cctttgtggt agatatgctt
    30001 aatcaagaaa tgggacgaaa cttggaagtt attcaacgtc atggggccct gctcttggtt
    30061 gaaaatgggc aactcttgta tgtagaattg cctaaagaag gggtcaatgt tcatgatttc
    30121 tttgagacaa gcaaggtcag agaaaccttg ttgattgcga ctcgtaacga aggcaaaacc
    30181 aaggaattcc gagctatctt tgataagtta ggctacgatg tggaaaatct taatgactac
    30241 cctgacctgc ctgaagtagc agaaacaggt atgacctttg aagaaaatgc ccgccttaag
    30301 gcagaaacca tttctcaatt aacgggtaag atggttttgg cagatgattc tggtctcaaa
    30361 gtcgatgtcc ttggtggctt accaggcgtc tggtcagctc gtttcgcagg tgtgggagca
    30421 actgaccgtg aaaataatgc caaactcttg cacgaattgg ccatggtctt tgaactcaag
    30481 gaccgctcgg ctcagttcca cacaacccta gtcgtagcca gcccaaataa ggaaagttta
    30541 gttgttgaag cagactggtc aggttatatt aactttgaac ctaagggtga aaatggcttt
    30601 ggctatgatc ccctcttcct tgtaggagag acaggtgagt catcagctga attaacccta
    30661 gaagaaaaaa atagtcaatc tcaccgtgcc ttagccgtta agaaactttt ggaggtattt
    30721 ccatcatggc aaagcaaacc atcattgtaa tgagcgattc ccatggcgat agcttgattg
    30781 tggaagaagt ccgtgatcgc tatgtgggca aagtcgatgc cgtttttcat aacggcgatt
    30841 ctgaactacg tccggattct ccactttggg agggcatccg cgttgttaaa gggaacatgg
    30901 acttctacgc cggctaccca gaacgtctgg tgactgagct tggttcgacc aagattatcc
    30961 aaactcatgg tcacttgttt gacatcaatt tcaactttca aaagttggac tactgggctc
    31021 aggaggaaga ggccgctatc tgcctctatg gtcacttgca tgtgccaagt gcttggttgg
    31081 aaggcaagat cctctttcta aatccaggtt ctatcagtca accacgaggt accatcagag
    31141 aatgtctcta tgctcgtgtg gagattgatg atagttactt caaagtggac tttttgacac
    31201 gagatcacga ggtgtatcca ggtttgtcca aggagtttag ccgatgattg ccaaggagtt
    31261 tgagactttc ttgttggggc aggaggaaac ttttttgacc cctgctaaaa atctagctgt
    31321 gttgattgat acccacaatg cggatcatgc gaccctcttg ctcagtcaga tgacctatac
    31381 ccgtgttccc gttgtgacag atgaaaaaca gtttgttggg acgattggac tcagagatat
    31441 tatggcttat cagatggagc atgacttgag ccaagaaatc atggcggata cggatatcgt
    31501 tcatatgaca aaaacggacg tagcggttgt ttcgcctgat ttcaccatta cggaggtctt
    31561 gcacaagcta gtagatgagt ccttcttacc ggtcgtggat gcagagggta ttttccaagg
    31621 gattattacg cgcaagtcca tcctcaaggc cgttaatgcc ctcttgcatg actttagtaa
    31681 ggaatatgag attcgatgcc aatgagagac aggatttcag cctttttaga ggaaaagcag
    31741 ggcttgtctg tcaattccaa gcagtcctat aagtatgatt tggagcaatt tttagacatg
    31801 gtaggtgagc ggatttctga gaccagtctc aagatttacc aagcccagct agccaatcta
    31861 aaaatcagcg cccagaagcg aaagatttcg gcctgtaacc aatttctata ctttctctat
    31921 caaaaaggag aggtggacag cttttaccgc ttggaattag ccaaacaagc tgaaaagaag
    31981 acggaaaagc cagagattct atacctagac tctttttggc aggaaagcga ccatccagag
    32041 ggccgcttgc tagcgctctt aatcctagaa atggggctct tgcccagtga gattttagcc
    32101 atcaaggttg cggacatcaa tctggatttt caggtgctgc gaatcagcaa ggcttcccaa
    32161 cagaggattg tcaccattcc cacggccttg ctttcagaat tggaaccctt gatggggcag
    32221 acctatcttt ttgaaagagg agagaaaccc tattctcgtc agtgggcctt tcgtcagtta
    32281 gaatcttttg tcaaggagaa aggttttcca tccttatcag ctcaagtctt acgtgaacag
    32341 tttattctaa gacaaataga aaacaaggtc gatttgtacg aaattgcaaa aaaattagga
    32401 ttaaaaacag tcctgacctt agaaaaatat agataatgga tattaaatta aaagattttg
    32461 aaggacccct ggacttgctc ttgcatctgg tttctaagta ccagatggat atctacgatg
    32521 tgcccattac ggaagtcatc gaacagtatc tagcctatgt ctcaaccctg caggccatgc
    32581 gtctggaagt gacgggtgag tacatggtca tggctagtca gctcatgctg attaagagtc
    32641 gtaaactcct tccgaaggta gcagaagtga cagacttggg ggatgacctg gagcaggacc
    32701 tcctctctca aatcgaagaa tatcgcaagt tcaagctctt gggtgagcac ttggaagcca
    32761 agcaccaaga acgggcccag tattattcca aagcgccgac agagttgatt tacgaagatg
    32821 cggagcttgt gcatgacaag acgaccattg acctcttttt ggctttttca aatatcctag
    32881 ccaagaaaaa agaggagttt gcacaaaatc acacgacgat cttgcgggat gagtataaga
    32941 ttgaggacat gatgattatc gtgaaagagt ccttgattgg acgagatcaa ttgcgcttgc
    33001 aggatttgtt caaggaagcc cagaatgtcc aagaggtcat caccctcttt ttggcaaccc
    33061 tagagttaat caaaacccag gagctgatcc tcgtgcaaga ggagagtttt ggagatatct
    33121 atctcatgga aaagaaggaa gaaagtcaag tgcctcaaag ctagacttga tagagaggaa
    33181 agatgagtac tttagcaaaa atagaagcgc tcttgtttgt agcgggtgaa gatgggattc
    33241 gggtccgcca gttagctgaa ctcctctctc tgccaccgac aggcatccag caaagtttag
    33301 gaaaattagc ccagaagtat gaaaaggacc cagattccag tttggctttg attgagacaa
    33361 gtggtgctta tagattggtg accaagcctc aatttgcaga gattttgaag gaatactcta
    33421 aggcgcctat caaccagagc ttgtctcggg ctgcccttga gaccttgtcc attattgcct
    33481 acaaacagcc gattacgcgg atagaaattg atgccatccg tggagttaac tcgagtggag
    33541 ccttggcaaa gttgcaggct tttgacctga taaaggaaga cgggaaaaag gaagtattgg
    33601 ggcgccccaa cctctatgtg actacggatt atttcctaga ttacatgggg ataaaccatt
    33661 tagaagaatt accagtgatt gatgagcttg agattcaagc ccaagaaagc caattatttg
    33721 gtgaaaggat agaagaagat gagaatcaat aagtatattg cccacgcagg tgtggccagt
    33781 aggagaaaag cagaagagct gattaagcaa ggcttggtga cggttaacgg ccaagtggtg
    33841 cgtgaactag caaccactat caagtcaggc gacaaggtcg aagttgaagg tcaacctatc
    33901 tacaacgaag aaaaggtcta ctatctgctt aacaaaccac gcggtgtgat ttccagtgtg
    33961 acagatgata agggtcgcaa gacggttgtc gacctcttgc ccaatgtcaa agagcgtatt
    34021 taccctgtgg gtcgtttgga ctgggataca tcaggtgtct tgattttgac caatgatggg
    34081 gactttacag acgagatgat tcaccctcgt aatgagattg acaaggttta tgtcgcgcgt
    34141 gttaaaggtg tggccaataa ggacaatctc cgccccttga cccgtggtct tgagattgat
    34201 ggtaagaaaa ccaagccagc tgtttatgaa attctcaaag tggacccagt caaaaatcgc
    34261 tctgtggtgc agttgaccat ccatgaaggg cgtaaccatc aggttaaaaa gatgtttgaa
    34321 gctgttggtc tccaagtaga taagttgtct cggactcgtt tcggacacct agacttgaca
    34381 ggactccgtc caggagaatc ccgtcgtctt aataaaaaag aaatcagcca actacacacc
    34441 atggctgtaa ctaagaaata atgaaacgaa ttttaatagc gcctgtgcgc ttttaccaac
    34501 gttttatctc accagtcttt ccaccctctt gtcgctttga gctgacttgt tccaactaca
    34561 tgattcaggc tattgaaaaa catggtttta agggggtatt gatgggcttg gctcggattt
    34621 tacgttgtca tccctggtcg aaaacaggta aggaccccgt tccagaccac ttttccctta
    34681 aacgaaatca agaaggggaa tgaggtgggg taaatagatt tcaaaatgat aaaaacgcat
    34741 cctatcaggt ttgagtaaac ttgataggat gcgttttaga atgtcaaaat tttatactct
    34801 tcgaaaatct cttcaaaccg cgtcagcttt catctgcaac ctcaaaacag tgttttgagc
    34861 aacctgcggc tagtttccta gtttgctctt tgattttcat tgagtattaa attgagtttg
    34921 aagtggctta tttcaaagct ttttgtatgt cttcaatcat gagttttgtt gattcaagtc
    34981 cgcctccgct tagataccag aggtctggtg ttagttggat aatcttacca tttttagcag
    35041 caggtgtttc agcgataagg gcattttcta ggacaccgtc gttgctagag ttgtccccac
    35101 cgatggcaag ggtacggttg atgacaaaga ggatgtcagg gttgatttct ttgacacttt
    35161 caaagctgac ttcttgtccg tggcgtgagt cttcaaattt tgtatcagtt ggtttgaatt
    35221 tcaaggtttg gtacaagaaa gagaaacgag atttggcacc aaaggctgcc atttttcctt
    35281 cattaaggag gatcgcaagg gcttttttgt cagagctttc atttttagta gcgacttctt
    35341 ggatgctctt gtctagcttg gccaattctt ccttggcttt ctgtgtacca gtttcgccga
    35401 aggcacttgc taaggattcg atattagcct tggtagaagt ccagtagtcg tccttgcttg
    35461 cttggaagag aacggttggg gcgatttctt tgaatttgtc tacgaatttt tgtgtacgtg
    35521 gtgaagcgat aatcaaatca ggctcaaggg cggcgatagc ttctaaatca ggttctttca
    35581 tagaaccaac atttttgaca gttcccacta ggtcttttag ataagtcgga acagtttttg
    35641 taggcattcc gacgatattt ttttcaaatc ctaaagcgcg aatagtatcc gcagcgccga
    35701 ggtcaaaggt cacaatcttt tcaggaactt tggaaagttt gacctcggcc agtgaacttt
    35761 taatggttac ctctgttgga gcagagctac tggtctctgt ctgactagtg cttgagtttg
    35821 tactacatgc accaagtagg agcaagaagc tggccactag ggcagtgaaa taaagtttaa
    35881 gggatgtttt cataatttct cctctttaaa atgtgataac gatttaggga gtctcttgat
    35941 cttattgact aagagactga aggttctcta acttgagctt ttatgttact agctatagat
    36001 acagatcttt ttgtcattga tatcagctag cgtgatggga atctcataaa gttgactgag
    36061 caggtcagcc tgcatgattt gatcggttct tcccttgcta aagacctggc cgtccttgaa
    36121 ggcgacaatt tcatctgcat actgactggc tatgttgata tcgtggagga cgatgataat
    36181 ggtcttgccg agttcctcca ccagtcgtcg aagaatctgc atcatgctga cgctttgctt
    36241 gatatcgaga ttgttgagtg gttcgtccag caagataaag tccgtatcct gggccagtac
    36301 catagcgata aagacgcgct ggagttgccc ccctgacagg ctattgatgt agcggtcttt
    36361 taagttggtc agttccaaat agttcagagt ttctcggatt ttttcccagt cttctgatct
    36421 aagtcgacct cggctgtagg gaaaacgtcc aaaactgacc agttcttcaa cagtcaattt
    36481 ggcttggtaa ttgattttct gttttaggat ggttagttct tgggccagtt cttgcgaatt
    36541 ccagctctcg atttcacgtc ctttgatact gagaactccc tgatctttct tggttagtct
    36601 gctcatgatg gagaggagag tcgattttcc agcaccattt ggaccaataa aggctgtcag
    36661 tttttgagga ctgacttcaa gcgaaatgcc ttgcaaaata tcctgttttt gaatggattt
    36721 gtcaatgttt tccagtttca ctgacgagcc ctcctatata gtaagataaa gaataagaag
    36781 ccacccacac tctcaatgat catactgata cgaatttcca gtgcaaagac tcgttcaatc
    36841 aaggcttgcc ccaaggttaa gctaataaat ccaaccagaa tggccactat aaagagtaac
    36901 ttgtgctgat agtctttgac aatcaggtag gtgaggttgg ccagcataaa gccgaagaag
    36961 gccataggtc ctaccaagga agtggccgtt gaggtcaaaa gcacgattcc ccagaggagc
    37021 tctttctgtt ctttttcaac atcgagtccc aatatctgag ccgtttctct ttgcaggtgc
    37081 aagacatcta gaacgactgc ttttcgaaag aaaaagattg tcaaagcgag gatgatcaga
    37141 gaaccgatgg ctaggatgga agtgttgaga tgttgaaagg aggcaaaaag actattttgc
    37201 agtttatcgt attcgtttgg atccattagg acttgaagga aggtgctgat atttcgaaag
    37261 agacttctga gcgctagaca gatcagcagg atgaagacca ggtcttgctt catcagtgtc
    37321 ttcaagtaac cttgtaaggc gagaaagaag agggactgga caagaagtaa gactaggaat
    37381 tctaagatag gggatttgcc aagttgaaga aacttgcttt caaaaaccag tagtagggtt
    37441 tgtagtagga cgtagaagga ttcaattccc aaaatactag gcgtcaggaa gcgattttcc
    37501 gtcagggttt gaaaactaat ggtcgaaatc ccagtcgcga tggctaccaa gagataaacg
    37561 atgatctttt gggaacgcaa cttccaagca aaggctgaca agtgagtgat gggccaaaag
    37621 tagagaagac aagctccgat ggcaagaata atgagaatcc agaagagctt ggtatgtttg
    37681 cttttagtct gcatcttttc gtccccctct ccagagaagt aggataaaga cgagactacc
    37741 gatgattcct agcaagagac tgacagacaa ctcatagggc ctaatcagaa ctcgggatag
    37801 gatatcgcaa gccagaacta gattggcacc aaccagtgcg accatgagtt tggtttgact
    37861 tagattatct ccatagcgct tgcgaacaag attgggaacg ataactccga gaaatggtag
    37921 gccacccacg gtaatcatgg tgacgcttgt cgttagcgcc accagaaaga gggccagttt
    37981 ttcaagtagg gagtaggaaa tccccaaact ctcgctggtt tctttcccta gattcatgat
    38041 ggtgaaggtt tgggataatt tccaaacggt tatcaggatg atgaggccta agaagagcca
    38101 ctcatactga tgggtctgaa tcatggagaa ggagccctgg gtccaggcag tcatactctg
    38161 aaccagattg aaacgatagg cgataacttc tgtgactgag ccgataatcc cgctatagat
    38221 gatcccaatc agaggcaaca tccacctttc ctttacagta aaaatggtca taaaggctag
    38281 gaagaagagg gtgaatacga tggatgaaac aaaagcgaag agcatctttt gggtcagact
    38341 agccgatgga aagacaaaaa ggctcagcac cattcccagt ttggcggctt cagtcgttcc
    38401 aactgtactc ggtgcagcaa actgattttg ggtaatagtc tgcatgagaa ggcctgccat
    38461 actcatacta gaggcagtca ggagaatact gatagttctt gggagacggg actcttgaaa
    38521 gaggagccag gtctgctggt cgaaatcaaa tagctttccc catgaaaaat cattggtccc
    38581 aatgctaata gagagaaaga ctaggagtag aagtaagcca attaaataat gagaaagttt
    38641 cataccccgt cctttcatgt agatttggta tcgaaagata tctgcggata taaatgtaac
    38701 attatttttc taatctgtca ataaaatttc tgacaattta ataaatacaa caaggagaga
    38761 gcaacaagac tttctccttt gttatcctat tctaaaatgt ttttacctta atctgataaa
    38821 ataatatctt cgagggagta gctagccgtc caatcaagat attgtttagc ttttgaagca
    38881 tctgctagga cactggctgg gtcactagca cgtcgagcaa caatctcgtg tgggattttt
    38941 taatttagta attcttcagc agttttaaag atttctttga tagtatagcc ttttttagtt
    39001 cctaagttaa agatttgaga agaactgtct tcttgaaata ggtagttcat tcctttaaca
    39061 tgagcctatg caaggtccaa gacataaatg taatctcgaa tacatgaacc gtcacgtgta
    39121 tcgtagtcat ctccaaatat ttttaagcta tcattttgtc ccaatgcggt cttgttgata
    39181 tttggaatga tgtgagttgg atttttcaca cgcagaccgt ttgaagcatc catttcagcc
    39241 ccagcaacat taaagtaacg gaaaataaca tatttccagt cgtagcgatt ggccatccag
    39301 taaatcattc gttcgcccat cagttttgtc tctgcataag ggttgacagg gtcgagcagg
    39361 gtatcttcag tcaccggctt gtcaatacag ttatttccat agagagaagc agtcgaagag
    39421 aacatgattt tttgaatgcc aacttcagat aagactttga gaacttggtt cataccagca
    39481 acgttggcag tgaagtattt acttggattt tcaatacttt cgctcacaac aatttcacct
    39541 gcacaatgga ggacagcatc aatctgattt tcttctaagt aagcctttaa ggcgctagca
    39601 tcataaacat ccagttcttt aaagctagca cgactatcca cagccgctcg atttcctgtg
    39661 gagagattat cgaggacatg caccttatag ccagcattta aaagagcttt aacggtatgg
    39721 gagccaatgt agctagtccc acctgtaaca agaattgttt tggtcatgat tttttccttt
    39781 tctagttttg tactatagta aattgaaata agatatgaac aactctatta ggaaagtcaa
    39841 attaatttct agaaatgttt cagcagctac agcgtactat tccaaactca accaactata
    39901 tatttaaaga aagaagaaag ggaagtcaac tattttctgt aaatttcatg aaaaatccaa
    39961 acaactttga tggtgtattg tttttttgtt tggaaataaa tattcgagtt aattttggaa
    40021 tgtttactag attttgcact acatgcaaga gaatactatc cttttctaag atagagcagg
    40081 actaagatac taacttagaa atccaccttc ccactatcct tctcctataa aaagtggtaa
    40141 aatggatgaa agaaagaagg aactgaaatg acaacattat tttcaaaaat taaagaagta
    40201 acagaacttg ctgcagtctc aggtcatgaa gcgcctgtcc gtgcttatct tcgtgaaaag
    40261 ttgacaccgc atgtggatga agtggtgaca gatggcttgg gtggtatttt tggtatcaaa
    40321 cattcagaag ctgtggatgc accgcgcgtc ttggtcgctt ctcatatgga cgaagttggt
    40381 tttatggtca gcgaaatcaa gccagatggt accttccgtg tcgtagaaat cggtggctgg
    40441 aaccccatgg tggttagcag ccaacgtttc aaactcttga ctcgtgatgg tcatgaaatt
    40501 cctgtgattt caggttctgt tcctccgcat ttgactcgtg gaaagggggg accaaccatg
    40561 ccagccattg ccgatatcgt ttttgatggt ggttttgcgg acaaggctga ggcagaaagt
    40621 tttggcatcc gtcctggtga taccatcgta ccagatagtt ctgcaatttt gacagccaat
    40681 gaaaaaaata tcatctcaaa agcttgggat aaccgctacg gtgtcctcat ggtaagcgag
    40741 ctagctgaag ctttatcagg tcaaaaactc ggcaatgaac tctatctggg ttctaacgtc
    40801 caagaagaag ttggtctgcg tggcgctcat acctctacaa ccaagtttga cccagaagtc
    40861 ttcctcgcag ttgattgctc accagcaggt gatgtctacg gtggtcaagg caagattgga
    40921 gatggaacct tgattcgttt ctatgatcca ggtcacttgc ttctcccagg gatgaaggat
    40981 ttccttttga caacggctga agaagctggt atcaagtacc aatactactg tggtaaaggc
    41041 ggaacagatg caggtgcagc tcatctgaaa aatggtggtg tcccatcaac aactatcggt
    41101 gtctgcgctc gttatatcca ttctcaccaa accctctatg caatggatga cttcctagaa
    41161 gcgcaagctt tcttacaagc cttggtgaag aaattggatc gttcaacggt tgatttgatt
    41221 aaacattatt aaaccataag ggaggtggta gggatggtag aaccaaacct agaaagcctt
    41281 ataaaagatc tttacaatca tgctcgacat gatttgagtg aagatttagt tgctgctctc
    41341 ctagagacta ctaaaaaact gcctactaca aatgagcaat tgcaggcagt tcgtctctca
    41401 agcctggtca atcgtgaatt gctcctaaat cccaaacatc cagcacctga gttgctcaac
    41461 ttggctcgct ttgtcaaaag agaagaagcc aagtacagag gaactgcgac ttctgcgctt
    41521 atgtatgagg aactttttaa aatgctttga ttccattgtg gatcaaagca ttttttataa
    41581 gacctatctc gtgagcgttc aaatagtagt aacaaggaat catgagaagt cagccgagac
    41641 catagtagtg aagaaacttc tgtaatggaa gtggagtgaa gtgaggaatc gtcaaacggt
    41701 aggggatagg ctgtttgaag ggtgctacga aaaagatagg gtaaggtgaa attatagcgg
    41761 aatgaaataa gatatgaaca aattgattag ggaaatcaaa tgaatttata gaaatctttt
    41821 agcagtcatg gcgtcctatt ctagtttcaa aatgctataa atacgaacaa attgattggg
    41881 aaattcaaat cgctttctat caatgtttta gaagatacag tgccctagtc caacttcaat
    41941 atactataaa agaacagatg gaagcaatta tgatttactt ctatctttaa aataaatgat
    42001 ctgataggaa aaatgtgtcc cctcataaaa aataggatag tacggatgga aggcttttgt
    42061 agactggagg acgaaggaat ttagaaactc tcgttaaaag ttagttgagc cggagtatgg
    42121 tggtgtgaat aattatcaaa aattatttcc aaatcgaaat agttgacagt tagaacgatg
    42181 agtgttacaa ttattttatt catttcgata tcgaaataaa ttggaggtgt tatgaaagat
    42241 agtcatttgc tagcccatca tattcgtttg ttgaatgggc ggatttttca aaagttactg
    42301 agtcaagatc ctgaggctct ttataggggt gaacagggca agattttagc ggttttatgg
    42361 aatagtgaaa ctggctgcgc aactgcgaca gatatcgcgc ttgcgactgg gcttgcgaat
    42421 aatacgctga cgactatgat aaaaaagcta gaggaacaaa agcttgtaat tgttagtccg
    42481 tgtggaaaag acaagcgtaa gaagtattta gttttaacgg agttaggcaa gttccagaaa
    42541 gaagtggggc atcgtgtcag tcagaaattg gatactatct tttacaaagg attttcagag
    42601 gaagaaattc accaatttga aggttttcaa gaaagaattt tggcaaatct gaaagagaag
    42661 gaaaatgagg tttagaatat gtcacaacaa gtgaaaaatg ctcacaacct atacatccat
    42721 gccattcaag acggacgagt tgctgaggct caagcccagt ctgtagggga tacctatatc
    42781 caacattcga caggtgttcc tgacgggaaa gaaggatttg cagccttctt tgcagatttc
    42841 tttgagcgtc atccagagcg tcagattaag attgtccgca ccattgagga tggcaatctg
    42901 gtctttgttc atgttcatca atatctgaat ggtggagaag ctcaatgggt gacgacggat
    42961 actttccgtg cggatgagaa tggttgtatt gttgagcatt gggatgtcat tgactactat
    43021 cgaacacctg aaaatgatca actagatcaa atttttggag attttgaaat caaggatttg
    43081 gataagaaag cagaaaataa aaagctggtt cgccgtttct tgacagaaat tttccaaaat
    43141 ggggagctag agcagtggag tgattatgtg gcagacgatt tgattcagca taatcatgag
    43201 attggacaag gaagtgctgc ttataaaaac tatgtggctg aatatagtgt cacttttgac
    43261 tttgttttcc aactcttagg acaaggaaac tatgtggtta gctatggtca gactcagatt
    43321 gatggcgttg cttatgccca gtacgatatc ttccgtttag agaacgggaa aattgtggag
    43381 cattgggata ataaggaagt catgcctaag gtagaagact tgaccaatcg agggaagttt
    43441 taaattgagg acaaagaatg attgaataca aaaatgtagc actgcgctac acagaaaagg
    43501 atgtcttgag agatgtcaac ttacagattg aggatgggga atttatggtt ttagtagggc
    43561 cttctggatc aggtaagacg accatgctca agatgattaa ccgtcttttg gaaccaactg
    43621 atggaaatat ttatatggat gggaagcgca tcaaagacta tgatgagcgt gaacttcgtc
    43681 tttctactgg ttatgtttta caggctattg ctctttttcc aaatctaaca gttgcggaaa
    43741 atattgctct cattcctgaa atgaaggggt ggagcaagga agaaattacg aagaaaacag
    43801 aagagctttt ggctaaggtt ggtttaccag tagccgagta tgggcatcgc ttacctagtg
    43861 aattatctgg tggagaacag caacgggtcg gtattgtccg agctatgatt ggtcagccca
    43921 agattttcct catggatgaa cccttttcgg ccttggatgc tatttcgaga aaacagttgc
    43981 aggttctgac aaaagaattg cataaagagt ttgggatgac aacgattttt gtaacccatg
    44041 atacggatga agccttgaag ttggcggacc gtattgctgt cttgcaggat ggagaaattc
    44101 gccaggtagc gaatcccgag acaattttaa aagtgcctgc aacagacttt gtagcagact
    44161 tgtttggagg tagtgttcat gactaattta attgcaactt ttcaggatcg ttttagtgat
    44221 tggttgacag ctctatctca acatttgcag ttgtcacttt tgaccttgtt actagctatt
    44281 ttgcttgcga ttcccttggc tgtttttctt cgctatcatg agaagctggc cgactgggtc
    44341 ttgcagattg ccggtatttt ccagaccatc ccgtctctgg ccttgttggg gctctttatc
    44401 cctttgatgg gaattgggac cttgccggct ttgacagctc tagtgattta tgcgattttc
    44461 cctattttgc aaaatactat cactgggctg aagggaattg atccgaacct gcaagaggct
    44521 gggattgcct ttgggatgac cagatgggaa cgtctcaaga aatttgaaat tccactcgcc
    44581 atgcctgtta tcatgtctgg gattcggacg gcagctgttt tgattatcgg tacggcaacc
    44641 ttggcggcct tgattggagc agggggactg ggttccttta tcctgttggg aattgaccgt
    44701 aataatgcca gtttgatttt gattggggca ctttcttctg cagtgcttgc tatcgccttt
    44761 aacttcctac taaaagtaat ggaaaaagca aaattacgga cgattttctc aggttttgcc
    44821 ttggtggctt tattactggg tctgtcttat agtccagctc ttttggttca aaaagagaag
    44881 gaaaacttgg ttattgctgg gaaaataggt ccagaaccag aaattttggc caatatgtat
    44941 aagttgctga ttgaagaaaa taccagcatg actgcgactg ttaaaccgaa ttttgggaag
    45001 acaagcttcc tttatgaagc tctgaaaaaa ggcgatattg acatctatcc tgaatttact
    45061 ggtacggtga ctgaaagttt gcttcaacca tcacccaagg tgagtcatga accagaacag
    45121 gtttatcagg tggcgcgtga tggcattgct aagcaggatc atctagccta tctcaaaccc
    45181 atgtcttatc aaaacaccta tgctgtagct gtttcgaaaa agattgctca agaatatggc
    45241 ttgaagacca tttcagactt gaaaaaagtg gaagggcagt tgaaggcagg ttttacactc
    45301 gagtttaacg accgtgaaga tggaaataag ggcttgcaat caatgtatgg tctcaatctt
    45361 aatgtagcga ccatggagcc agcccttcgc tatcaggcta ttcagtcagg tgatattcaa
    45421 attacggacg cctattcgac tgatgcggaa ttggagcgtt atgatttaca ggtcttggaa
    45481 gatgacaagc aactcttccc accttatcaa ggggctccac tcatgaaaga agctcttctc
    45541 aagaaacacc cagagttgga aagagttctt aatacattgg ctggtaagat tacagaaagc
    45601 cagatgagcc agctcaacta ccaagtcggt gttgaaggca agtcagcaaa gcaagtagcc
    45661 aaggagtttc tccaagaaca aggtttgttg aagaaatgat gggacagaga ctttaaacat
    45721 actgaactca acttccttaa acgactagat aaaagaatgc tcagacaatt tcgtctgggc
    45781 ttttttgatg tgagaatgac tgaatgtcac ttaaaatgga aagaaagaga aaattttcat
    45841 gattttctaa aattttactg taaagacagt tgactattca taaaataggt gtataatatt
    45901 ttgtgaacta cttaacaaat aaggggtttc agctcatgtc gactaaggtt agaaatcttg
    45961 tgtataggca gttcattatc taatagagcg ttgcgtccga aagtctatcc agacacggct
    46021 ctttaaaaac aaaaggagaa atgatgcata cttatttgca aaagaaaatt gaaaatatca
    46081 aaacaaccct aggtgaaatg tcaggtggtt accgtcgtat ggttgcggct atggctgatt
    46141 taggattttc aggaactatg aaggctatct gggatgacct ctttgcccat cgtagttttg
    46201 cccagtggat ttatttgctg gttttaggaa gttttcctct ctggctggag ttggtttacg
    46261 aacatcgtat tgttgactgg attgggatga tttgtagctt gacagggatt atctgtgtaa
    46321 tctttgtatc ggaaggtcga gcaagtaatt atctttttgg cttgattaac tctgttattt
    46381 accttatttt ggccctacag aaaggctttt atggtgaggt gctgacgaca ctttacttca
    46441 cagtcatgca gccaattgga cttctagttt ggatttatca ggcacagttt aagaaggaaa
    46501 agcaggagtt tgtcgcgcgt aaactggacg gcaagggctg gacaaagtat ctttccatta
    46561 gtgtgctttg gtggttggcc tttggcttca tttatcagtc tattggtgcc aatcgtccct
    46621 atcgtgattc aatcacagat gcaaccaatg gggtagggca aatcctcatg acagctgttt
    46681 accgtgaaca gtggatattc tgggcggcta ccaatgtctt ttcaatctat ctctggtggg
    46741 gagaaagcct gcaaattcaa gggaaatatc taatttatct cattaacagt ctagttggtt
    46801 ggtatcaatg gagcaaggca gctaagcaga atactgattt acttaactag gaaaagatgt
    46861 ttgaaagtgc tgttttgaga tttcgattaa aacagatata gttgataatc aaggatttat
    46921 agtatgaaaa agaggatcgg cgggtcctct tttgttgttg aaaagataaa aaactcagta
    46981 acctagaaat aagacaactg aagctttact ctatattcaa tttttaggaa tgagaaggtc
    47041 tagataaaat tggacaactt cctggtctgt gaaatcttga ccttttttga gccaccaggt
    47101 caatgtttcg ataaagttag ttacgacaaa atgttggagg taagaagtag gtagacttgg
    47161 gtgagtttgc ttcaaatcag cagccagcat gggatagacg tggtgctcaa gctctctctg
    47221 tagttgacgg aggaaatagt catttttgga aaatagcaga ctggcgatat ggtcttggtt
    47281 tttctgaaaa tggagaaaga ggtgggcgag gtagtcctcg gttgaaatgg cttgctctct
    47341 ttcaaaaaga tgatggaaga ggtagcggca gagctgatcc agaagaagct ctttactctc
    47401 atagtgacag taaaaggtgg atcgtcccac atctgcgaga tcaatgatat cctgaacagt
    47461 agtggtctcg tagtccttag cattcaaaag ttgtataaaa gcttgataga tggctttttt
    47521 ggttttgctg atacggcggt caatgttagt catatggaca cttgaggcaa attgttcaga
    47581 actgaataaa gctgacgttt tgcttctatc ctttctttga gttttagtgg ataatgataa
    47641 tgaacaaggt gttcataaat ctattataac aaaggaatga gaaatatgaa ggcaaaatat
    47701 gctgtttggg tggctttttt cttaaatttg acttatgcca ttgttgagtt tattgcaggt
    47761 ggagtatttg gttctagcgc tgttcttgct gactctgtgc atgacttggg agatgtgatt
    47821 gcaattggaa tatcagcttt tctagaaaca atctccaatc gtgaagaaga caatcagtac
    47881 accttgggct ataagcggtt tagcctgcta ggagccgtgg taacagctgt gattctcgta
    47941 acaggctctg ttctagtcat tttggaaaat gtcacgaaga ttttgcatcc gcaaccagtc
    48001 aatgatgagg ggattctctg gttaggaatt attgcgatta ctatcaatct gttagcgagt
    48061 ctggtggttg gtaagggaaa gacaaagaat gagtctattc tgagtctgca ttttctggaa
    48121 gatacgctag ggtgggtagc tgttatcctg atggcgattg ttcttcgatt tacggactgg
    48181 tatatcctag atcctctttt gtcccttgtc atttctttct ttattctttc aaaagccctt
    48241 ccacgttttt ggtctacact caagattttc ttggatgctg tgccagaagg tcttgatatc
    48301 aagcaagtaa agagtgacct ggagcgattg gacaatgtgg ccagccttaa tcagcttaat
    48361 ctctggacta tggatgcttt ggaaaaaaat gccattgtcc atgtttgtct aaaagaaatg
    48421 gaacatatgg aaacttgtaa agagtctatt cgaattttcc taaaagattg tggttttcaa
    48481 aatattacca ttgaaattga tgctgaccta gaaactcacc aaacccataa gcgaaaggtg
    48541 tgtgacttgg aacggagtta tgagcatcaa cattagaaaa aagtgaaaaa tacttgggta
    48601 ctatcttatt tggaatagag taatttcttt attatttaaa tatttcaaaa attggtaaga
    48661 gaagagcatt gtataaactc cagatatatg attgttaatg ataaaaattt ttcgattaga
    48721 tacaaaatgc ttgacttgga gtcaactcaa agttatataa taagataagt gagttagaat
    48781 agcgtgaatt cagtgaatga aatgagagga ggttagcgtg tgaatattaa atctgccagt
    48841 gatttgttgg gaatttcagc ggatacgatt cggtattatg aacgggttgg tcttgtgcca
    48901 ccgattactc gtactgctac tgggattcgt gattttcaag atcaggatat cgaagcgctg
    48961 gaatttatta agtgttttcg ttcggcgggt gtctctgtag atagtttagt tgactatatg
    49021 tcgctctacc aaaagggaga tgaaacgaga gaggagaggc ttggtatttt agaagaggaa
    49081 aagcaaaaat tagaggagcg cttgtctcag ctacagacag ctttaaatcg tttaaatctc
    49141 aaaattaaac tttataagga aggaaaattt taaatgaaat cagcagtata tacaaaggca
    49201 ggtcaggttg gacttgcgtc cgcaaataat agaagcggat gatgtgatta ttcgtgtggt
    49261 tcgtgcgtgc gtttgtggtt cagatttatg gaggtaccgt aatccagaaa cgaaagctgg
    49321 acacaaaaat agtggacacg aagcgattgg gattgttgaa gaagctgggg aagccattac
    49381 gacggtgaaa ccaggtgatt ttgtgattgt cccttttaca catggatgtg gtgagtgtga
    49441 tgcctgtctt gctggatttg acggttcttg cgacaatcat attggcaata atttgggggg
    49501 tgattttcag gcagaatata ttcgcttcca ctatgcaaac tgggcgctgg ttaaaatccc
    49561 tggtcaacct tctgactata cagaagggat gctcaagtcc cttttgactc ttgcagatgt
    49621 catgccgaca ggctatcatg cggcgcgtgt tgcaaatgtt caaaaagggg acaaggttgt
    49681 tgttatcggt gatggggctg ttggtcaatg tgctgtcatc gcggctaaga tgcgtggagc
    49741 atcacaaatt atccttatga gccgtcatga agaccgtcaa aagatggcta tggagtcagg
    49801 tgcgacagct gttgttgcag aacgtggtca agaaggaatt accaaggtgc gtgaaatcct
    49861 cggtggagga gcagatgcag cacttgaatg tgttggtacg gaggctgcta tagaacaggc
    49921 gctaggtgtt cttcataatg gagggcgtat gggctttgta ggagtcccac actataataa
    49981 tcgtgctctt ggttcgacat ttatgcaaaa tatctctgta gcaggtgggg cagcttctgc
    50041 tacaacatac gataagcaat ttttactaaa agccgtcctt gatggtgata tcaatccagg
    50101 tcgcgtcttt acttcaagtt ataaactgga agatatcgac caagcctata aagatatgga
    50161 tgaacgtaag acaattaagt ctatgattgt aatcgaataa aaaacgaata ggagttttag
    50221 aactctattc gttttttatg ttatcctatt cttgatttag ggtactttct cttaatgtca
    50281 gtctggttcc cagcatggtc aggctaggga ttttccgacc gtggaggact tccttgttaa
    50341 gaatatccat acctgctcgc cccatttctt cagtataaac tgtgatgctg gagaggggag
    50401 gataaacctg cttggtcagg ctggtgtcgt taaaggaaat gaggctgaca cggtctggta
    50461 ggctgattcc agcttcttgg agcgcacgaa gggcaccgat ggctaaacta tcgctggctg
    50521 cgaaaaatgc tggtgggagt tggtctccca agttctgaat ggcttccttc atcaagtcat
    50581 agccagactg ggcagtaaag tttccttgaa agatcagttc atcatgatag attccttttg
    50641 cttgactgta gtttctgaaa ttttccagcc gcttatcctc aatgatttct tcttggtcag
    50701 ttgtttcttc aaggcctgtt agaatcccga tacggtccat tccttggctg aggaaataat
    50761 cgacaacctg tttcatagca gtgtaaaaat ccgtgataat acaggtatgt cccagggaaa
    50821 gtgtatcgct gtctagaaat acaagaggct tttggtattc ttcaaaggca gaaatctgag
    50881 ctcggctaaa ttttccgatg cagagaatcc caatcacttc ctcgcttagg gtaaaaggat
    50941 ggtcattaaa atagcgcaag atatcgtagt ccaactcttg ggctcttttt tctattccta
    51001 ggcgaatctg gtagtagtag aggtcgtcta gctccccttg ttcgctgacc cattgaataa
    51061 tggcaatctt ttgcttgggt ttatgggact cgcctgtctt gaggtgcttg gtgtagccca
    51121 gctcttcagc aacggttaaa atacggtgtc tggtttcttc tgtaacagat aggctctggt
    51181 cgcggttgag gacacgggat acggtcgcga tagagacaga ggctagctgt gcaatgtctt
    51241 ttaaggtagc cataaatcct ccttgattag gttagtatat catatttttc ttctttttac
    51301 tgatagttta ctaaaatttt agtaaaaagg attgaccttg ggaaattcct tggatacaat
    51361 agaagaaaac gattacacgt taagatggct taacggacag tcaaaggaga attcatatgg
    51421 cacaacatct tactactgaa gtccttcgca aagactttct tgctgttttt ggtcaagaag
    51481 cagaccaaac cttcttttca ccaggtcgta ttaatttgat tggtgaacac acagactaca
    51541 acggtgggca cgtttttcct gctgctattt ccttgggaac ttacggtgca gctcgtaagc
    51601 gtgacgacca agtcttgcgt ttctactcag ctaactttga ggacaagggc attatcgaag
    51661 tgcctctcgc tgacctcaag tttgaaaaag agcacaactg gaccaattat ccaaaagggg
    51721 ttcttcattt cttgcaagaa gctgggcacg tgattgacaa aggttttgat ttttatgttt
    51781 atgggaatat cccaaatggt gctggcttgt cttcttcagc atccttggag ctcttgacag
    51841 gagtcgtggc agagcatctc tttgatttaa aattagagcg tctcgatttg gttaaaatcg
    51901 gcaaacaaac agaaaacaac tttatcggag tcaactctgg tatcatggac cagtttgcta
    51961 ttggtatggg ggctgatcaa cgtgctattt accttgatac caacacctta gagtatgatt
    52021 tggtgccact tgatttgaag gacaatgtcg ttgttatcat gaacaccaac aaacgccgtg
    52081 aattggcgga ctctaaatac aatgaacgtc gtgctgagtg tgaaaaagca gtggaagaat
    52141 tgcaagttgc cttggatatt cagaccctgg gtgaattgga cgagtgggcc gttgaccaat
    52201 atagctatct aattaaagat gaaaatcgtt tgaaacgtgc tcgccatgct gtgcttgaaa
    52261 accaacgtac ccttaaagct caagcagccc ttcaagcagg tgatttggaa acatttggtc
    52321 gtttgatgaa tgcgtcacac gtttctctgg agcatgatta tgaagtaact ggtttggaat
    52381 tagataccct tgttcacaca gcttgggcac aagaaggagt tctcggtgct cgtatgacag
    52441 gggctggttt tggtggctgt gccattgcct tggttcaaaa agatactgtt gaggccttta
    52501 aggaagctgt aggcaaacac tacgaggaag tagttggata cgctccaagc ttctatatcg
    52561 ctgaagttgc aggtggcact cgcgtccttg actagtcaaa aggaggctct atagtgacct
    52621 tagtagataa atttgtaaca catgtcattt ctgaaagttc atttgaggaa atggatcgaa
    52681 tctacctgac caatcgtgtt ttggcacgag tgggagaagg tgttttggaa gttgagacca
    52741 atctggataa attgattgac ctcaaggacc agctagttga ggaagccgtt cgattagaga
    52801 cgattgagga tagtcagact gcgcgtgaaa tccttggtac tgaactgatg gacttggtga
    52861 ctccttgtcc gagtcaggtc aatcgtgact tctgggaagc ctatgcctac tctcctgagc
    52921 aagcgataga ggatttttat caactcagtc agaaaaatga ctacatcaaa ctcaaggcca
    52981 ttgctaaaaa tatcgcttat cgtgttccat ctgattatgg agaacttgaa attaccatca
    53041 atctctctaa gcctgaaaag gatccgaaag agattgcggt agccaagttg gtgcaagcta
    53101 gtaattatcc tcagtgtcaa ctttgtttag agaatgaggg ttaccatggt cgggtcaacc
    53161 acccagctcg cagcaaccac cggattatcc gttttgaaat ggttggtcag gaatgggggt
    53221 tccagtattc gccctatgct tactttaatg agcattgtat ctttttagat ggccagcatc
    53281 gtcccatggc cattagtcgt cagagttttg aacgtctgtt ggctatcgta gagcagtttc
    53341 caggatattt tgctggatct aatgccgacc tgccgattgt ggggggctct attctaactc
    53401 acgatcatta tcagggaggc cgtcacgtat ttcctatgga attggctccc ttgcaaaaga
    53461 ccttccgatt tgctggtttt gagcaggtca aggctggaat tatcaagtgg ccaatgtctg
    53521 tcctacgctt gacttcggat tccaaagagg atttgattaa cttagctgat aagattttcc
    53581 aggaatggcg tcagtattca gattctagtg tgcagatttt agcagagaca gacgggacac
    53641 cgcatcacac catcacacca atagcgcgta agcgtgatgg acagtttgag ttggacttgg
    53701 tcttgcgaga caatcagact tcagcagagc atcctgatgg catctatcat ccccacaagg
    53761 atgtccaaca tatcaagaag gaaaatatcg gcttgattga ggtcatgggc ttggcaatct
    53821 tgccaccacg tctgaaagaa gaagtggagc aagtcgctag ctatcttgta ggagaagctg
    53881 ttacagttgc cgattatcat caggagtggg cagaccaact caaatcccaa catccagacc
    53941 taacggataa agaaaaagcc cttgcaatcg tcaaggactc tgtgggtgct atctttgtgc
    54001 gtgtacttga ggatgcagga gtctacaagc agacagaaca agggcagaca gcctttatgc
    54061 gctttgtgga acaggtcgga atttcactag actaggagct ttctccttgc acagtcctat
    54121 aaaaagtagt atcatagtgt cgtttgaaat atcaggagga aacgatgaaa gactttcatt
    54181 ttgacgctat atctgccttt gaaaattacg aaattgaaaa aatgagagat ggtcacgttg
    54241 tggtgacgac caaagtagtg aactcgtcgc tcaactacta tggcaatgcc catggtggct
    54301 atctattcac gctatgtgac caaatcagtg gtttggtggt tatctcgctg ggacttgatg
    54361 gggtgacact ccaatcctct atcaactacc ttaaggcagg aaaactcgac gatgtattga
    54421 ccattaaagg agaatgtgtc catcaaggtc gtacaacctg tgtgatggat gtggatatca
    54481 ccaatcaaga gggcagaaat gtctgtaaag caacctttac catgtttgtc acaggccaaa
    54541 ggtctgagga aagacgggta aggatataaa gaaaggtgag tgggataaat ttatctcact
    54601 catttttaat ttatgagata tgttagaagg aaatataaaa gagagtggtg aaatacaaat
    54661 gtaataggta catatatgtg gtatactagt tatagtagat tttaattgct tatatcgagt
    54721 gagttctcat attagtgagg aatttttaaa tggaattaca ctttaattta gaattagtag
    54781 aaacctataa aagtaatagc caaaaggcac gtatcttaac ggaggattgg gtttatcgtc
    54841 agtcttattg ccctaattat gggaacaatc ccttaaatca ttttgaaaat aatcggcctg
    54901 tagcagattt ttactgtaat cattgtagtg aggagtttga actaaagagc aaaaaaggaa
    54961 atttttcatc aacaatcaat gatggtgctt atgcaacgat gatgaagcgt gtgcaggcag
    55021 ataataatcc taatttcttt tttttaactt atacaaaaaa ttttgaggta aataattttc
    55081 tggtccttcc aaagcaattt gttacaccga aatcaattat tcaaaggaag ccacttgcgc
    55141 caactgctag acgagcaggt tggattggtt gtaacattga tttatcacaa gtaccttcta
    55201 aaggaagaat atttcttgtg aaaaatggac aagttagaga tccagaaaaa gttacaaaag
    55261 aatttaagca aagtttattt ttaaggaaga actctctttc agtaagaggt tggacaatag
    55321 aaattctaaa ttgtatagat aagatagagg gttcagaatt tacccttgaa gatatgtatc
    55381 gttttgaaag tgacctaaaa aatatctttg ttaagaacaa tcatatcaaa gaaaagatta
    55441 ggcaacagct tcaaatatta agagacaaag aaataataga atttaaaggt agaggaaagt
    55501 atcggaaatt atgaaaacga aacaacttgt tgcatcagaa gaggtgtatg atttcttaaa
    55561 agtcatctgg cctgattatg aaacagagag taattatgaa aacttatgtg taatggttta
    55621 tactttatca gaccctgatt gtgtgaggtg gttatctgaa aatatggagt ttggtgatga
    55681 gaaacaactt tctttattga ataaaaaata tagctgggaa tatggagatg aattaccaga
    55741 gtggttggaa agcccaaaac atagattatt gctaataagt gagttattgg agagaaactt
    55801 aagatgaaaa agtatacagt agaaattaca gaaactctaa cccgtttagt aagcatagag
    55861 gctgaaaatc cagatgaagc cgaacgactt gtaagagaaa agtataagag ttgtgaaatt
    55921 gttcttgatg cagatgattt tcaggacgat gagactagta tatatgagta gatgttttta
    55981 ttttgtcaca caaaaaagag gctcacacct ctttttctta tttcttttta tgatttaata
    56041 cggcattgag gacaatggca agtaggctgg ctacgacgat tccgtttgag aagaacattt
    56101 ggaaggctgt cggcatgctg acaaagagat tactgttgtt gagtccgaca cctgcagcaa
    56161 ttgatacagc tgcgataagg aagttgtgct cattgttagc aaagtcaaca cgggcgagga
    56221 tttgcatccc ttgaatagac acaaaaccaa acatcaccag catggcacca ccaaggacag
    56281 ggcttggaat gatttgagca agggcgccaa acttaggaag gagtccaagg agaaccagga
    56341 aaccagctgc gtagtagatt ggcaggcgag tcttgatacc tgacaattta accaaaccaa
    56401 cgttttgtga aaatcctgtg taagggaagg tgttaaagat tcctccgaga agtacggcca
    56461 aaccttctgc gcggtaaccg ttgcgaaggc gtgtgctatc gattgggtct ttcgtgatat
    56521 cagacaaggc tagataaaca ccagtagact caaccataga caccgttgcg atgatacaca
    56581 tcatgacaat agatgagatt tcaaaggttg gcatcccaaa gtagagggga gttgggacat
    56641 ggacaagagg tgctgctgca acaggagaga agtcaaccaa gcccatgcta gcagcaatgg
    56701 cagttccaac aaccagacca atcaaaatag agatagactt gataaatcct ttggtaaaga
    56761 tattaattaa gaggataatc acaacggtaa tagctgcaag tagaagactt tgaccagttg
    56821 gctctggaac gttatttccc atatttccaa tagcgacagg aatcaaggtt aaaccaatcg
    56881 tggtaatgac agatcctgtt acgatagatg ggaagagatt ggccactttt gagaagatgc
    56941 ctgaaacaag aaccacgtaa atacctgatg cgataagggc accaaacata gcaccactac
    57001 catggctttg cccaatcata atcaagggag cgacggattg gaaggcaact ccaagaacga
    57061 ctgggagtcc aatcccaaag tatttgttga gttggagttg gaggaaggtt gccaccccac
    57121 acatgaagat atctgtggaa atcaggtagg tcaactgctc agttgaatag ccaagggctg
    57181 tcgcaatcat gataggaacc aggatggatc ctgagtacat ggctagtaag tgctgcaagc
    57241 caagaacggc tgcttgcgaa tgtttttctt gagtttgcat tagagatctg cctccttaaa
    57301 tacgacttga ccattttcaa aacgatccaa acgagcgagt gatagaacag ggtagcctgc
    57361 tttttcaagc aaatcacggc cttcttggaa agatttttca atcacgatac cgatagcttc
    57421 gactgtggca ccagcttgtt cgatgatttg aatcaagcct ttggcagctt ggccattagc
    57481 aaggaaatcg tcgataatca agaccttgtc ctctggtgag aggaattttc tagcgataga
    57541 aacggtactg gtcacttgct tggtaaagga gtaaacttcg gcagttaaga ttccttcgtt
    57601 catagtgatg tttttagctt ttttagcgaa aatcatggga acgtttaagg cttcagctgt
    57661 aaaaatggct ggggcaatac ctgacgcttc aatggtcacg actttggtaa tgccagcaga
    57721 agcaaatttt tccgcaaaaa ccttaccaat ctctcgcatc aagctaaagt caacttggtg
    57781 ggttaaaaag gaatccacct tgaggatgtt atcacccaag atatgcccat ccttgaggat
    57841 gcgctcttct aataatttca taagacctcc taaagtctaa aagccaatcc atttgcttgt
    57901 ttcagatttc tacccagtaa aacggataga aaaaggacct acttaatctc taagtaagtc
    57961 cccaaaatag gcatggcaaa aacgaccata cctcacttct gacttactta ttgttaggtg
    58021 ttccggcacc ttgtagaaac gtcgtgccaa ttcacgacat aaacaagtaa aacgatattc
    58081 aatttcaaat aggcgtgagc caatgttttt attttacact aaataacttt ggaaatcaaa
    58141 tgttttgtta gtgttttggt ttaaaaagcg aacgaatata ataaaaatgg gcaaaagtta
    58201 acttattagc taacatttag aaggtttttt catcataaaa ggacatatta ttaggttttt
    58261 aaatgcctga caatatgcct ttttctgatt tgaaggattt tttctattct ctactcgcta
    58321 aatcttaaaa aatagccatc tggatccaag actgcaaatt catggggata tataaagcta
    58381 tctcctactc gaaattctct ttttgtcagg ggacgatgga taggatagtc agcttccagc
    58441 agtttttggt ggagctgagg aacatctaca atgccaaagg aaatattgac accgcgtccg
    58501 aaaggatagg tcagatcaac taattcatcc tttgttccct cctctaacat tagctgacaa
    58561 tcttcaagcg ataagaagag gaagttttct tctggtcgct cgtattcgat ggtaaaaccc
    58621 agcaaatcgc agtagaagtg gcgtgatttt tcgatgtcag atactacaaa ttcaggaatg
    58681 acagcttgat agtccattcg ttttctcctt agagttcaat ctccaagaca atcggtgtat
    58741 ggtcttggcg agcacctgag tcaatcatat cagatttagt gaccttgtct gcgagacggt
    58801 tacttgtgag ccagtagtcg attctccagc ctgtattgtt gattttagaa gtcttgctgc
    58861 gttgtgccca ccaagtgtag cgttctggga catcgccgtg aacatggcgg aaggtatccg
    58921 taaatccagt tgccaagaga ttggtaaatc cagcacgttc ctcgtcggta aatcctggtg
    58981 aacgacggtt gctggcagga tttgcaaggt cgatttcatt gtgggctaca ttgtagtcac
    59041 cggtcgcaag gactggtttt tctttgtcta gctcagccaa gtacgcagca tatttggcat
    59101 cccagacttg acgttcttcc aagcgtttga gaccatcgcc agcgtttgga gtgtaaactt
    59161 gggtcacgaa aaatttatca aattctagag tgatgatacg accttccaag tccatggtag
    59221 aaggggcacc gatttctggg aaagtgacag tgggtgtgag ttctttctta taaaggaaca
    59281 tggttccagc atagccttta cgggcaggtt cttgggaaga gcgccacgta ttttcgtagc
    59341 ctgggaagag ttcttctaaa atttccaagt gtttctttgt aggaccctta gcagaaagct
    59401 tggtttcttg gatagcgata atatcagcat tttcagcgac caaggtttgt aggacttctt
    59461 gggacaattt cgcgcgagct gagtcactag ttagggcagc attgagagaa tcaatattcc
    59521 atgagataag tttcataaag ttaccttttt cattcagatt atagatttta ttataccaaa
    59581 aaaaggtcta tttccccaat gtatggtttg aaaaatcacc ctctttcgtt tataattaag
    59641 aatgatttta tgaaaaggag tgaaaataaa tgaaatttta ctcatatgac tatgtgctta
    59701 gccaaatcag tcagcagaat gggattatga ttggctttgg gattgttctc ctagctatca
    59761 caggattttt tgcttttaag gcctatcgtg ataaaaaggg gactaagttt cgggaattgg
    59821 tcatgatttt ggccctgact ttagtggcca tgcttttggt gacaatttca aaataccaga
    59881 ccaatcaagc ctctaacaat caatttcaaa cctcccttca tttcatagag gttgtttcca
    59941 aagacttggg agtggataaa tcagaagttt acgtcaatac ttcagctgcc actgatggag
    60001 cgcttgtcaa ggtaggttca aatgtctatc gtgctatgaa cgggagccaa ccagacaagt
    60061 atcttttaga gaaaatagaa ttgcatcaaa cagacgctat tgaattggtg gaggtaaaca
    60121 aatgacactc aattatatgg aaattttaat caaactggcc ttggggctct tctctcttgt
    60181 ttttgttatc aatgtgacag gaaaaggaaa cctagcgcct aactctgcga cagaccaaat
    60241 tcagaactat gttcttggtg gtatcatcgg tggggtgatt tacaatagtt caattagtat
    60301 tctgcaatac gcagtgattt tgatgatgtg gacgattttg gtcttgaccc tcaaatggct
    60361 caacaataat gttcgttttg tcaaacgctt gattgatggg aaaccaactc tcctcatcaa
    60421 aaatgggcag atcgacccag aagcctgtcg ttcagttggc ttgtctgcag cggatgtagc
    60481 cctcaaactt cgtagccaag ggattttcca gatgaagcaa gttaaacgag ctgtgcaaga
    60541 gcaaaatggc caactcatcg tggtccaaat gggagatgaa aatcctaagt atccagttgt
    60601 gactgacggt gtgatccaag ttgatgtttt ggaatcgatt ggtcgtagcg aagagtggct
    60661 gcttgataac ctcagcaaac aaggacatga aaatgttgcc aatatcttta tagctgagta
    60721 tgacaagggt gctgttacag tcgtaactta tgaataagaa aaacctgggg tcttgtactc
    60781 ttcaaaaatc tcttcaaact gcgtcaacgt cgccttgccg tatgtatatg ttactgactt
    60841 cgtcagttct atctgcaacc tcaaagcagt gttttgagct gacttcgtca gttctatctg
    60901 caacctcaaa gcagtgtttt gagctgactt cgtcagttct atctacaacc tcaaagcagt
    60961 gctttgagca gcctgaggct agtttcctag tttgctcttt gattttcatt gagtattggc
    61021 ctcaggtttc catttgcaat cagaaaggga ttttatgtcc attattcaaa aactttggtg
    61081 gtttttcaag ttagaaaaac gccgttattt agtggggatt gtggctttgg tcttggtttc
    61141 cgtactcaat ctcattcccc ctatggtcat ggggcgggtc attgatgcca tcacatcggg
    61201 gcaattaacc cagcaggtcc tccttcttgc cctattttac ttgcttcttg cagcctttgg
    61261 gatgtactat ctgcgctatg tttggcgtat gtatatcctt gggacttcct accgtttggg
    61321 acagattatg cgctctcgct tatttgagca tttcacaaaa atgtctccag ctttttatca
    61381 aacctatcgg acgggggacc tgatggcaca tgccaccaac gatatcaatg ccctaacgcg
    61441 tctggcaggt ggcggagtca tgtcagcagt ggatgcctca atcacggctt tagtgacctt
    61501 gctgaccatg ctctttagca tttcatggca gatgaccttg gttgccattc ttcccctgcc
    61561 tttcatggct tatgcgacca gtcgtctagg gagaaagacc cacaaggctt ttggtgaatc
    61621 acaggctgcc ttttctgaac tcaataacaa ggtgcaggag tctgtatcag gtattaaagt
    61681 gaccaagtct ttcgggtatc aggcggacga gttgaagtct ttccaggcag ttaatgaatt
    61741 gaccttccaa aagaacctcc aaaccatgaa atacgatagt ctctttgacc ccatggttct
    61801 cttatttgtt ggttcctcct atgttttaac gctcttggtc ggctccttga tggttcagga
    61861 agggcaaatc acggttggga atctagttac ctttatcagc tacttggata tgctggtttg
    61921 gcctcttatg gccatcggtt tcctctttaa tattactcag cgaggcaagg tttcttacca
    61981 gcggattgag gaacttttgt ctcaggaatc acctgtacaa gacccggagt ttcctttaga
    62041 tggtattgaa aatgggcgct tgcagtatgc cattgatagc tttgcctttg aaaatgagga
    62101 aacactgaca aatgttcact ttagtttgga aaaagggcaa actctgggtt tggttggaca
    62161 gacaggctct gggaaaacgt ccttgatcaa actcctcttg cgtgaatacg atgtggatag
    62221 gggagccatt tacctaaacg gtcacgatat tcgggactat cgtctgacag atcttcgcag
    62281 tctcatgggc tatgttcctc aggaccagtt cctctttgcg acttcaattt tagacaatat
    62341 tcgctttggc aattctaagc tgcctctttc agcggtcgag gaagcgacca agctagccca
    62401 agtttaccaa gacattgtag ccatgcctca gggatttgat acgctgattg gtgaaaaggg
    62461 agtcagtctt tctggaggtc aaaagcagcg tctggccatg agtcgggcta tgattttaga
    62521 ccctgatatc ttgattttgg atgattcctt atcagccgtg gatgccaaga cagagtatgc
    62581 gattatcgac aaccttaagg agatgcgaaa ggacaagaca accatcatca cagcccatcg
    62641 cctgagtgca gttgttcatg cagatttgat tttagtcctg caaaatggtc aaatcatcga
    62701 acgaggcagg cacgaagact tgctagccct ggatggctgg tatgcccaaa cctaccagtc
    62761 tcagcagttg gaaatgaaag gagaagaaga tgcggaataa gaaagaacaa tgggatgtat
    62821 tgaagcgcct gatgtcctat ctcaagcctt atggactcct gacctttttg gcactcagtt
    62881 ttctactagc gacgacggtc attaaaagtg tcattcctct tgtggcttcc cactttatcg
    62941 accagtatct gagtaatctt aaccaactgg ccattaccgt tttgctggcc tactatggcc
    63001 tttatatcct acaaactgta gttcagtatg tcggcaatct tctctttgcg cgggtatcct
    63061 acagcatcgt tagagatatt cgtcgggatg cctttgccaa tatggaaaag ctgggcatgt
    63121 cttattttga caagacgcca gcaggttcta tcgtttctcg tttgaccaac gataccgaga
    63181 cgattagtga tatgttttct gggattttat ccagctttat ctcagcagtt tttatctttc
    63241 tgacaaccct ttataccatg ttggtgttgg attttcgttt gacagcttta gtcctgctct
    63301 ttcttccctt gattttcctt ttggtcaata tctaccggaa aaagtcagtc aagattatcg
    63361 agaaaaccag aagtctcttg tcagatatca atagtaagct ggcagagaac atcgagggaa
    63421 tcagaattat ccaggccttt aatcaagaga aacgcctgca gacggaattt gatgagatta
    63481 accaagaaca cttggcctat gccaaccgtt ctgtagcctt ggatgccctc tttttgcgcc
    63541 ctgccatgag tttgctgaaa ctcttaggtt atgcggtctt gatggcctac tttggctatc
    63601 gtggccttta tctgggaata acagctggaa ccatgtatgc ctttattcag tacatcaacc
    63661 gtctctttga ccccttgatt aaggtgacgc aaaacttttc aaccctgcaa acgtctatgg
    63721 tttctgcagg ccgagtattt gccttgattg acgagagaac ctatgagccg cttcaaaatg
    63781 atgggcaagc caaaatccaa gaaggcaata ttcggtttga acatgtatgt ttctcatatg
    63841 atggcaagca cccgattctg gatgatattt ctttttctgt taagaagggt gaaaccattg
    63901 cctttgtggg tcatacaggt tctgggaaat cgtctattat caatgtcctc atgcgttttt
    63961 atgaatttca gtcaggccta gttctcttgg atgatgtgga tatcaggaac tacagtcagg
    64021 aagagttgag aaaaaacatc ggtctggtct tgcaggatcc tttcctctat catggaacaa
    64081 tcaagtccaa tatctccatg taccaagaga tcagtgatga gcaggtaaag gacgcagcta
    64141 cttttgtcga tgcagcttcc tttattcagg atcttcctca gggttatgat tcccctgttt
    64201 ctgagcgtgg gtcgagtttc tctactgggc agcgccagct tctggccttt gctagaacag
    64261 tagccagtca gcctaaaatc ctgattttgg atgaagcgac agccaatatt gactctgaaa
    64321 cagaaagttt ggttcaagct tctctggcga agatgagaca gggccgaaca actattgcta
    64381 tcgctcaccg cctttctact attcaagacg ccaactgcat ctatgtcttg gataagggac
    64441 gcattatcga gagtggaacc catgaggaac tcttggctct gggaggaact tatcacaaga
    64501 tgtatagttt gcaggcaggg gccatggccg atactctttg aaaatctctt taaaccatgt
    64561 cagctttatc tgcaatctca aagctgtact ttgattttca ttgagtacta gaaggaaatc
    64621 cttcaaatta cagatttctt tcaccgcctt ttccattttg tggtataatg aaaaatgttg
    64681 acaaatagta taataaaaac aaaggagaac agcatgctga aatgggaaga cttgcctgtg
    64741 gaaatgaaat caagcgaggt tgagtcttac taccagcttg tctctaaaag gaagggttcg
    64801 ctgattttca agcgttgctt ggactgggtt ttggccttgg tcttactggt tctaacctct
    64861 cccatctttc tcatcttgag catttggatc aagttggata gcaaggggcc agtgatttac
    64921 aagcaagagc gtgtgaccca gtacaaccgt cggttcaaga tttggaagtt ccgtaccatg
    64981 gtgacggatg cggataaaaa aggaagtctg gtgacttctg ctaacgatag ccgtattacc
    65041 aaggttggaa atttcatccg acgtgtccgt ttggacgaac tgcctcagtt ggtcaatgtc
    65101 cttaaaggtg agatgtcctt tgtcggtaca cgacctgaag tgccacgtta tacagagcag
    65161 tatagccctg aaatgatggc aaccttgctc ttgcaagcag gaattacctc tccagccagc
    65221 atcaactaca aggatgagga caccatcatc agtcaaatga cggagaaagg tctgtcagtt
    65281 gatcaggcct atgtggagca tgttcttcct gaaaagatgc gctataacct cgcctatctc
    65341 cgagagttta gtttctttgg ggacatcaaa atcatgtttc aaaccgtgtt tgaggtacta
    65401 aaataaagta gtcataagaa aatgagtaca gataaaagga gcaaatcaat gccaaattac
    65461 aatattccat tttcaccgcc tgatatcaca gaagcagaaa ttgctgaagt agcggatacc
    65521 ctgcgttctg gttggatcac aacaggtcct aaaacaaaag aactggagcg ccgcttgtct
    65581 ctttacacac agacacctaa gactgtttgt ctcaactctg cgacagccgc tctggagttg
    65641 attttacgcg ttttggaagt gggacctggt gatgaagtca tcgttccagc catgacctat
    65701 acggcttcat gtagtgtcat tacgcacgtg ggagcaaccc ctgtcatggt ggatatccaa
    65761 gcagatacgt ttgagatgga ctatgacctg cttgagcaag ctatcactga gaaaactaag
    65821 gtgattatcc cagtagagct cgcagggatt gtttgcgatt atgaccgttt gttccaagtc
    65881 gtggagaaaa aacgtgactt ctttaccgct tcaagcaagt ggcaaaaggc ctttaaccgt
    65941 attgtcattg tctctgatag tgcccacgct ttgggatcta cttataaagg acaaccttct
    66001 ggttctatcg ctgactttac ttccttctca ttccatgccg ttaagaactt tacaacggca
    66061 gaaggtggaa gtgcgacttg gaaagccaat ccagtgattg atgacgaaga gatgtacaag
    66121 gaattccaaa tcctttccct tcacgggcaa actaaggatg ctcttgccaa gatgcaactg
    66181 gggtcatggg aatacgatat cgttacacca gcctataagt gcaacatgac cgatatcatg
    66241 gcttcacttg gtttggtaca attggaccgc tatccaagtt tgttgcaacg ccgtaaggac
    66301 attgtggacc gctatgatag tggttttgca ggttctcgca tccatccttt ggcacacaag
    66361 actgaaactg tcgaatcttc acgccacctc tacatcaccc gtgtagaagg agcaagccta
    66421 gaagaacgca acctcatcat ccaagaattg gctaaagcag gaattgcaag taatgttcac
    66481 tacaaaccgc ttcctctctt gacagcctat aagaatcttg gatttgatat gacgaactat
    66541 cctaaggcct atgccttctt tgagaatgaa attaccctcc ctcttcatac taaattaagc
    66601 gatgaagaag tagactatat cattgagact ttcaaaacag tttctgaaaa agtgctaact
    66661 ttatcaaaaa aatgacaaac tacagtcaag cgaaagtgat cctgtcctta aaaaatctaa
    66721 ttgagtgtaa aaactgttgt tttcaattga taatagttta cacctgtagt tgaggctcct
    66781 ttctcctcag agagagaatt tttataggat tttcctttct tgtgggagtc ccgtggtttg
    66841 aaataagatg tgagcaattt ggtgtagcat ttagaatcct tactagacat catttagaaa
    66901 atctagtgtc ttgttctagt tttcaattca ccctattttt tgaaagacgt gagtttccat
    66961 gagtgagatt gtggaaactc gcgtcttttt ttgttttcag aatattgggc tctttgtcaa
    67021 ctgtagtggg ttgaagtcag ctaagctcga gaaaggacaa aattcgtcct ttcttttttg
    67081 atgttcagag cgataaaaat cctttttttg aagttttcaa agttccgaaa tccaaaggcg
    67141 tttcgtttga taagtttgat gagattattg gtcgcttcca attttgcgtt ggaataaggt
    67201 aattgaagag cgttgacgat ttt
//
LOCUS       DAVLCS010000008        63472 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLCS010000008 DAVLCS010000000
VERSION     DAVLCS010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.008"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            720..1712
                     /locus_tag="VXC78_000592"
     CDS             720..1712
                     /locus_tag="VXC78_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0582716.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQKIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VXC78_000593"
     CDS             1714..2532
                     /locus_tag="VXC78_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV0582717.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VXC78_000594"
     CDS             2534..3319
                     /locus_tag="VXC78_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0582718.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3417..3635
                     /locus_tag="VXC78_000595"
     CDS             3417..3635
                     /locus_tag="VXC78_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV0582719.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3620..3781
                     /locus_tag="VXC78_000596"
     CDS             3620..3781
                     /locus_tag="VXC78_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0582720.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNP"
     gene            complement(4243..4317)
                     /locus_tag="VXC78_000597"
                     /pseudo
     CDS             complement(4243..4317)
                     /locus_tag="VXC78_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4550..10984
                     /locus_tag="VXC78_000598"
     CDS             4550..10984
                     /locus_tag="VXC78_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV0582721.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDNRIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
     gene            11616..12092
                     /locus_tag="VXC78_000599"
     CDS             11616..12092
                     /locus_tag="VXC78_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0582722.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            12130..12435
                     /locus_tag="VXC78_000600"
     CDS             12130..12435
                     /locus_tag="VXC78_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0582723.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            12483..13958
                     /locus_tag="VXC78_000601"
     CDS             12483..13958
                     /locus_tag="VXC78_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV0582724.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNSAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            14263..20964
                     /locus_tag="VXC78_000602"
     CDS             14263..20964
                     /locus_tag="VXC78_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV0582725.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWHF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNNFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFLYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(21212..22068)
                     /locus_tag="VXC78_000603"
                     /pseudo
     CDS             complement(21212..22068)
                     /locus_tag="VXC78_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(22279..22638)
                     /locus_tag="VXC78_000604"
     CDS             complement(22279..22638)
                     /locus_tag="VXC78_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV0582726.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            22730..23686
                     /locus_tag="VXC78_000605"
                     /pseudo
     CDS             22730..23686
                     /locus_tag="VXC78_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            23670..24227
                     /locus_tag="VXC78_000606"
     CDS             23670..24227
                     /locus_tag="VXC78_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0582727.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            24220..24474
                     /locus_tag="VXC78_000607"
     CDS             24220..24474
                     /locus_tag="VXC78_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582728.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            24486..26540
                     /locus_tag="VXC78_000608"
     CDS             24486..26540
                     /locus_tag="VXC78_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV0582729.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            26719..27579
                     /locus_tag="VXC78_000609"
     CDS             26719..27579
                     /locus_tag="VXC78_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV0582730.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            27790..28500
                     /gene="ccdA2"
                     /locus_tag="VXC78_000610"
     CDS             27790..28500
                     /gene="ccdA2"
                     /locus_tag="VXC78_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0582731.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            28520..29086
                     /locus_tag="VXC78_000611"
     CDS             28520..29086
                     /locus_tag="VXC78_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV0582732.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            29097..30209
                     /gene="msrB"
                     /locus_tag="VXC78_000612"
     CDS             29097..30209
                     /gene="msrB"
                     /locus_tag="VXC78_000612"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0582733.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEIMLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            30477..31214
                     /locus_tag="VXC78_000613"
     CDS             30477..31214
                     /locus_tag="VXC78_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0582734.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            31211..32902
                     /locus_tag="VXC78_000614"
     CDS             31211..32902
                     /locus_tag="VXC78_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0582735.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            33018..33581
                     /locus_tag="VXC78_000615"
     CDS             33018..33581
                     /locus_tag="VXC78_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV0582736.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKT"
     gene            33603..39272
                     /locus_tag="VXC78_000616"
     CDS             33603..39272
                     /locus_tag="VXC78_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEV0582737.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGYLSGDILKTLGLDTV
                     LEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEPKS
                     EIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEPKV
                     EQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSE
                     LNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDA
                     LNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTGVTEAEKVAANTDAKQSEVNSETAS
                     LKTAISRLNTDKVELENQLKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQEQ
                     INEAEKSLKTALADLSVDKTALGSAIDTATKKNKENYTNQTWAELETALTAAKSVNTN
                     ESKQSDVNEAAEKLTATMEKLVELSEKPRLTLSIEKRDIDRKATVTYTLENPANTQIK
                     SITATLKKGEEVVKDFVLTEENLKTNHLTALFEKLDYYKEYTLSTDMVYNRGNDDETE
                     SISEELIQLNLKKLELKDIQTVSLMKFENGQESQVTHLSDKPTDLSKLYLKVTSSTSK
                     DAVLAVSSIEEEIIENKKIFKIHADTPELVVRKKDGSLSKGFDYYMERVIPHDGDIYY
                     DFKDLISAMTSNPTGTFILGRDISSRNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIF
                     DLEYPLFDTIKSGVVKDIDFKHVNMVFPDSNQGDNVATIARVIKDKTKIENVNVEGYL
                     EGRDHVAGLVNNLEGNSEIENVSFTGKIKSKGGNSITAGIAGRNILSRVKRAYVNADI
                     EVHRSSNSSMLVAVNGINADASGGWGTWGRLTESVAKGTLETKQGGQAGGASSTVWPY
                     GAIDNVVSYAKVTKGKELFGSDGDLNYDWFMKKISNIFGVQGISSGDSGSDSKFTRIS
                     EEEANQKVASYNITAPNLMSDSSLLVDRLNESWKNTDQFESIQDYQAQNQLIYQNLTK
                     FTPYYNKEFIVHEGNALTPEQEILKTKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGS
                     QKRYKVTSTGKFSITNLPEYQVEDLNVVYTSEHIVHPLDSSLINNLVEELKKVELYTE
                     STYQVLGIDKDNANKLNRTKRLFLDESLDAVKTQLPTFVKTMFENEWLHINGESSGAV
                     AALRQKIMDNKTAILLALTYINRYYDVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRL
                     GSSGENRLKGSENAETFKQLFASETKQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDY
                     IQFEERPSLVEEIKDAKYRVYDNLTAPYYQGYILPLLTLKNTHLAILSNYSTMTFVSR
                     EKRPNWKNEDFDKWVKYVATAHRNHVDTWYKILPDNIKGKMVKENVTAVWEGLSIPGS
                     EWVDQNAVDRKGRDYAPAREFFNLVGGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSE
                     YGISVFTHELTHVNDTWIYLGGYGRRENMGPEAYAQGLFQSPVPGQPGWGALGLNMAF
                     ERKNDGDLIYNASPTQFENRKELDSYMKNYNDTLMMVDYLEGDAVISKGKEAITKWFK
                     KVEPKVVSQTAQYDTVRQLTAEEKEKLSVSSVDDLVDQGLMSDRAVGNNTYNPADFET
                     SYIAIDYMTGIYGGGKNSVGSPGALMFKHNTFRMWGYYGFEEGVLGYASNKFKQASRD
                     EGHAGLSDNFIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKTYSTFEE
                     LQEGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQTDSFKTSIFR"
     gene            39333..41054
                     /gene="pabB"
                     /locus_tag="VXC78_000617"
     CDS             39333..41054
                     /gene="pabB"
                     /locus_tag="VXC78_000617"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV0582738.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFHSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGKISQKQLMFEE
                     QHLERLRKASRYFAYPFDPEILRQKIEAECQTCDANQDYRLRISLSKSGEIEFSRQIL
                     TPLSPSFCQAKLCLQEANLNQSFTYFKTTYRPHLSIEEQEKIYHNGKGELLETSIGNL
                     VLKIDGKLYTPPIRLGILPGIYHQYLLETGQVEEKVLTLADFAQAEAIYGCNAVRGLY
                     ELQVIGL"
     gene            41174..42700
                     /locus_tag="VXC78_000618"
     CDS             41174..42700
                     /locus_tag="VXC78_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0582739.1"
                     /translation="MKSKIVLGASLAIATLSLVSLVEIEGLSPFLIENVSANTHSANK
                     VINHKVSIYLENADEGKGLTVNFSTDSVSPNLFDEFEKKSGITITTMLVNAKTGEVVE
                     KRLTPSVFLRSNDLTSGTISSFIFSEYPDGEYKYVVSKGDFIDPKTQFKHQYRGESPV
                     FRIRNRKYVELGTTDKKLDERRDNSVYKDGVVEHKVNLSLTSYQGGNGVTAIFSTDSV
                     NSNLLNSFGEKAKKVLIRSKLINVKTGEVIDETFSPKVSLTSKILKSGSTAVFYFIDL
                     TDGEYKYVAYESQQYTDPQTTLTHQYRGESPIFSIKDGKFSGLVSASKPDENPKPTPK
                     PDEKPKPSAPQQEKTKPTVQSGWVGSSYYQNGKKVTSKWIFDKKYNSYFYLDASGNYV
                     QNAWVGNYYLKSGGYMAKSEWIYDKNYGSYYYLTSEGSYARNTWSGNYYLKSNGKMAK
                     SEWVYDSNYKSYYYLTSEGSYARNTWVGNYYLKSNGKMAVNERTPDGYRVDGSGKWVK
                     "
     gene            42787..43706
                     /locus_tag="VXC78_000619"
                     /pseudo
     CDS             42787..43706
                     /locus_tag="VXC78_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            43841..44800
                     /locus_tag="VXC78_000620"
     CDS             43841..44800
                     /locus_tag="VXC78_000620"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV0582740.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFELAKEEDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            44897..45736
                     /locus_tag="VXC78_000621"
     CDS             44897..45736
                     /locus_tag="VXC78_000621"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV0582741.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(45784..45954)
                     /locus_tag="VXC78_000622"
     CDS             complement(45784..45954)
                     /locus_tag="VXC78_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV0582742.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            46075..46959
                     /gene="miaA"
                     /locus_tag="VXC78_000623"
     CDS             46075..46959
                     /gene="miaA"
                     /locus_tag="VXC78_000623"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV0582743.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            46952..48190
                     /gene="hflX"
                     /locus_tag="VXC78_000624"
     CDS             46952..48190
                     /gene="hflX"
                     /locus_tag="VXC78_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV0582744.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            48183..48806
                     /locus_tag="VXC78_000625"
     CDS             48183..48806
                     /locus_tag="VXC78_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV0582745.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            48821..49750
                     /locus_tag="VXC78_000626"
     CDS             48821..49750
                     /locus_tag="VXC78_000626"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV0582746.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            49771..50526
                     /locus_tag="VXC78_000627"
     CDS             49771..50526
                     /locus_tag="VXC78_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0582747.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(50580..51488)
                     /locus_tag="VXC78_000628"
     CDS             complement(50580..51488)
                     /locus_tag="VXC78_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0582748.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            51552..51821
                     /locus_tag="VXC78_000629"
     CDS             51552..51821
                     /locus_tag="VXC78_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV0582749.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            51821..52201
                     /locus_tag="VXC78_000630"
     CDS             51821..52201
                     /locus_tag="VXC78_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0582750.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            52290..52517
                     /locus_tag="VXC78_000631"
                     /pseudo
     CDS             52290..52517
                     /locus_tag="VXC78_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(52557..53282)
                     /locus_tag="VXC78_000632"
     CDS             complement(52557..53282)
                     /locus_tag="VXC78_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV0582751.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGKILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTILKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            53444..55285
                     /gene="typA"
                     /locus_tag="VXC78_000633"
     CDS             53444..55285
                     /gene="typA"
                     /locus_tag="VXC78_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV0582752.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            55305..55559
                     /locus_tag="VXC78_000634"
     CDS             55305..55559
                     /locus_tag="VXC78_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV0582753.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            55923..56222
                     /locus_tag="VXC78_000635"
                     /pseudo
     CDS             55923..56222
                     /locus_tag="VXC78_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            56293..58314
                     /locus_tag="VXC78_000636"
     CDS             56293..58314
                     /locus_tag="VXC78_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0582754.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASFFILRSRDWVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            58316..58957
                     /locus_tag="VXC78_000637"
     CDS             58316..58957
                     /locus_tag="VXC78_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582755.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLDLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWGQVDQVIRVTDLSHR"
     gene            59061..60413
                     /locus_tag="VXC78_000638"
     CDS             59061..60413
                     /locus_tag="VXC78_000638"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV0582756.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            60415..61473
                     /locus_tag="VXC78_000639"
     CDS             60415..61473
                     /locus_tag="VXC78_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV0582757.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQALFSKGG
                     FVSVPPVIAACVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            61483..62703
                     /gene="divIB"
                     /locus_tag="VXC78_000640"
     CDS             61483..62703
                     /gene="divIB"
                     /locus_tag="VXC78_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV0582758.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYISVLFNDSEQIKAFT
                     SELAQINPELKVAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGVYSYTVADKLIMEAEEKAKKEAEEAEKRQEEERKRLEEEQKKQEE
                     ESNRNQTTQRSSRR"
BASE COUNT        20132 a        11136 c        13744 g        18460 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat taatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta caaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cggtgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tatttcatga
      541 gagaaatcct aatttcacaa tctataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttctgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aacattttgt gaagattgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgtatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg agcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca aaagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctatc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttcg tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttaatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagga acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaggc agttgtcgtt gaggttttga
     3421 aggatttgcc agaatggttt ggaatcccag aaagcacaca agcctatata gaaggaacca
     3481 cgacactgca agtttggacc gcctatcagg agagtgattt gactggattt gtaaggttat
     3541 cctattcgag tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg
     3601 tagaaaaatt gggagccaat tgcttgctac tttagagagt gaagctcgta aaaaagttgg
     3661 ttatctgcag gtcaaaacag tggcagaagg ttctaataaa gattatgatc gaacaaatga
     3721 cttttatcga ggtcttggct ttaaaaagtt agagattttt tctcagctat ggaatccgta
     3781 aaatccttgt cagattttga ttaaaaagct tgaataatat tacttgacat ctattctcag
     3841 agtgccatac tgtaagtgta atcgccgatt tagctcagtt ggtagagcaa ggcactcgta
     3901 aagcctaggt tataggtaga taaacgactg aggagttgaa aaaatagata ggtagaagat
     3961 aaccgttaag ccttattctt agcggttatt tatattgttt aatagcgctg atatttcatc
     4021 aattatgcct gttttcgtgt ttctggtagt tgttcaagtt tattgctact atttttgatg
     4081 gtatgaatgt gcttataatg tatcccggtt aacgaaagtt ttggacttat actcatagaa
     4141 aatctcttca aaccacgtca acgtcgcctt gccgtgcgta tggttactga cttcgtcagt
     4201 tctatccaca acctcaaaac agtgttttga gctgactacg tcagttccat ctacaacctc
     4261 aaaacagtgt tttgagcaac ctgcggctag tttcctagtt tgctctttga ttttcattga
     4321 gtactaatct tattttttaa cgtgtgctaa aaaataaatt aatgcatgtt aatttttctt
     4381 gaattaaatt tttttaaatg atatactgtt tttatggaga gataacaatt atatataaat
     4441 gtactactct atttcctaga taatacttag taaaactttt tataacaaag gctagcaaag
     4501 ttaaagttta ttatctattg gaagttaaat aaatatgtaa ggaattaaaa tgaaaaaaag
     4561 tacagtattg tcattaacca cagctgcagt tattttagca gcctatgccc ctaatgaggt
     4621 agtcttagca gacacatcta gctctgaaga tgctttaaac atctctgata aagaaaaagt
     4681 agtattagat aaggaaacag aaaataaaga gaaacatgaa gatattcata atgctataga
     4741 aacttcaaag gatactgaag aaaagaaaac aacagttatt gaggaaaaag aagttgttag
     4801 taaaaatcct gtgatagaca ctaaaactag caatgaagaa gcaagaatca aagaagattc
     4861 caatcaatcc caaggagata atgcacactc gtctgcaaat aaaggcacag aaaatccgaa
     4921 aaaagaagat agacttgtct atattgctga atttaaagat aaagaatctg gagaaaaagc
     4981 aatcaagcaa ctatccaatc ttaagaatac aaaagtttta tatacttatg atagaatttt
     5041 taacggtagt gccatagaaa caactccaga taacttggac aaaattaaac aaatagaagg
     5101 tattacatcg gttgaaaggg cacaaaaagt ccaacccatg atgaatcatg ccagaaagga
     5161 aattggagtt gaggaagcta ttgattacct aaagtctatc aatgctccgt ttgggaaaaa
     5221 ttttgatggt agaggtatgg tcatttcaaa tatcgatact ggaacagatt atagacataa
     5281 ggctatgaga atcgatgatg atgccaaagc ctcaatgaga tttaaaaaag aagacttaaa
     5341 aggaactgat aaaaattatt ggttgagtga taaaatccct catgcgttca attattataa
     5401 tggtggcaaa atcactgtag aaaaatatga tgatggaagg gattattttg acccacatgg
     5461 gatgcatatt gcagggattc ttgctggaaa tgatactgaa caagatatca aaaactttaa
     5521 cggcatagat ggaattgcac ctaatgcaca aattttctct tacaaaatgt attctgacgc
     5581 aggatctggg tttgcgggtg atgaaacaat gtttcatgct attgaagatt ctatcaaaca
     5641 caacgttgat gttgtttcgg tatcatctgg ttttacagga acaggtcttg taggtgagaa
     5701 atattggcaa gctattcggg cattaagaaa agcaggcatt ccaatggttg tcgctacggg
     5761 taactatgcg acttctgctt caagttcttc atgggattta gtagcaaata atcatctgaa
     5821 aatgaccgac actggaaatg taacacgaac tgcagcacat gaggatgcga tagcggtcgc
     5881 ttctgctaaa aatcaaacag ttgagtttga taaagttaac ataggtggag aaagttttaa
     5941 atacagaaat ataggggcct ttttcgataa gaataaaatc acaacaaatg aagatggaac
     6001 aaaagctcct agtaaattaa aatttgtata tataggcaag gggcaagacc aagatttgat
     6061 aggtttggat cttaggggca aaattgcagt aatggataga atttatacaa aggatttaaa
     6121 aaatgctttt aaaaaagcta tggataaggg tgcacgcgcc attatggttg taaatactgt
     6181 aaattactac aatagagata attggacaga gcttccagct atgggatatg aagcggatga
     6241 aggtactaaa agtcaagtgt tttcaatttc aggagatgat ggtgtaaagc tatggaacat
     6301 gattaatcct aataaaaaaa ctgaagtcaa aagaaataat aaagaagatt ttaaagataa
     6361 attggagcaa tactatccaa ttgatatgga aagttttaat tccaacaaac cgaatgtagg
     6421 tgacgaaaaa gagattgact ttaagtttgc acctgacaca gacaaagaac tctataaaga
     6481 agatatcatc gttccagcag gatctacatc ttgggggcca agaatagatt tacttttaaa
     6541 acccgatgtt tcagcacctg gtaaaaatat taaatccacg cttaatgtta ttaatggcaa
     6601 atcaacttat ggctatatgt caggaactag tatggcgact ccaatcgtgg cagcttctac
     6661 tgttttgatt agaccgaaat taaaggaaat gcttgaaaga cctgtattga aaaatcttaa
     6721 gggagatgac aaaatagatc ttacaagtct tacaaaaatt gccctacaaa atactgcgcg
     6781 acctatgatg gatgcaactt cttggaaaga aaaaagtcaa tactttgcat cacctagaca
     6841 acagggagca ggcctaatta atgtggccaa tgctttgaga aatgaagttg tagcaacttt
     6901 caaaaacacg gattctaaag gtttggtaaa ctcatatggt tccatttctc ttaaagaaat
     6961 aaaaggtgat aaaaaatact ttacaatcaa gcttcacaat acatcaaaca gacctttgac
     7021 ttttaaagtt tcagcatcag cgataactac agattctcta actgacagat taaaacttga
     7081 tgaaacatat aaagatgaaa aatctccaga tggtaagcaa attgttccag aaattcaccc
     7141 agaaaaagtc aaaggagcaa atatcacatt tgagcatgat actttcacta taggcgcaaa
     7201 ttctagcttt gatttgaatg cggttataaa tgttggagag gccaaaaaca aaaataaatt
     7261 tgtagaatca tttattcatt ttgagtcagt ggaagaaatg gaagctctaa actccaacgg
     7321 gaagaaaata aacttccaac cttctttgtc gatgcctcta atgggatttg ctgggaattg
     7381 gaaccacgaa ccaatccttg ataaatgggc ttgggaagaa gggtcaagat caaaaacact
     7441 gggaggttat gatgatgatg gtaaaccgaa aattccagga accttaaata agggaattgg
     7501 tggagaacat ggtatagata aatttaatcc agcaggagtt atacaaaata gaaaagataa
     7561 aaatacaaca tccctggatc aaaatccaga attatttgct ttcaataacc aagggatcaa
     7621 cgctccatca tcaagtggtt ctaagattgc taacatttat cctttagatt caaatggaaa
     7681 tcctcaagat gctcaacttg aaagaggatt aacaccttct ccacttgtat taagaagtgc
     7741 agaagaagga ttgatttcaa tagtaaatac aaataaagag ggagaaaatc aaagagactt
     7801 aaaagtcatt tcgagagaac actttattag aggaatttta aattctaaaa gcaatgatgc
     7861 aaagggaatc aaatcatcta aactaaaagt ttggggtgac ttgaagtggg atggactcat
     7921 ctataatcct agaggtagag aagaaaatgc accagaaagt aaggataatc aagatcctgc
     7981 tactaagata agaggtcaat ttgaaccgat tgcagaaggt caatatttct ataaatttaa
     8041 atatagatta actaaagatt acccatggca ggtttcctat attcctgtaa aaattgataa
     8101 caccgcccct aagattgttt cggttgattt ttcaaatcct gaaaaaatta agttgattac
     8161 aaaggatact tatcataagg taaaagatca gtataagaat gaaacgctat tcgcgagaga
     8221 tcaaaaagaa catcctgaaa aatttgacga gattgcgaac gaagtttggt atgctggcgc
     8281 cgctcttgtt aatgaagatg gagaggttga aaaaaatctt gaagtaactt acgcaggtga
     8341 gggtcaagga agaaatagaa aacttgataa agacggaaat accatttatg aaattaaagg
     8401 tgcgggagat ttaaggggaa aaattattga agtcattgca ttagatggtt ctagcaattt
     8461 cacaaagatt catagaatta aatttgctaa tcaggctgat gaaaagggga tgatttccta
     8521 ttatctagta gatcctgatc aagattcatc taaatatcaa aagcttggcg agattgcaga
     8581 atctaaattt aaaaatttag gaaatggaaa agagggtagt ctaaaaaaag atacaactgg
     8641 ggtagaacat catcatcaag aaaatgaaga gtctattaaa gaaaaatcta gttttactat
     8701 tgatagaaat atttcaacaa ttagagactt tgaaaataaa gacttaaaga aactcattaa
     8761 aaagaaattt agagaagttg atgattttac aagtgaaact ggtaagagaa tagaggaata
     8821 cgattataaa tacgatgata agggaaatat tattgcttat gacgatggta gtgccttaca
     8881 atatgaaact gaaaaacttg acgaaataaa atcaaaaatt tatggcgttc taagcccatc
     8941 taaagatgga cactttgaaa ttcttggaaa gataagcaat gtttctaaaa atgccaaggt
     9001 atattatgga aatagctata aatcgataga aatcaaagcg actaagtatg actcacattc
     9061 aaaaacgatg acatttgatt tatacgctaa tattaatgat attgtggatg gattagcttt
     9121 tgctggagat atgcggtttt ttgttaaaga tgataatcga ataaaagctg aaactaaaat
     9181 tagaatgcct gaaaaaaata aggaaactaa agcagaatat ccctatgtat caagttatgg
     9241 gaatgtaatc gaattaggag aaggagatct ttcaaagaac aaaccagaca atttaactaa
     9301 aatggaatct ggtaaaatct attctgattc agaaaaacaa caatatctgt taaaggataa
     9361 catcattcta agaaaaggct atgcactaaa agtgactacc tataatcctg gaaaaacgga
     9421 tatgttagaa ggaaatggag tctatagcaa ggaagatata gcaaaaatac aaaaggccaa
     9481 tcctaatcta agagtccttt cagaaacaac aatttatgct gatagtagaa atgttgaaga
     9541 tggaagaagt acccaagctg tattaatgtc ggctttggac ggctttaaca ttataaggta
     9601 tcaagtgttt acatttaaaa tgaacgataa aggggaagct atcgataaag acggaaatct
     9661 tgtgacagat tcttctaaac ttgtattatt tggtaaggat gataaagaat acactggaga
     9721 ggataagtcc aatgtagaag ctataaaaga agatggctcc atgttattta ttgataccaa
     9781 accagtaaac ctttcaatgg ataagaacta ctttaatcca tctaaatcta ataaaattta
     9841 tgtacgaaat ccagaatttt atttaagagg taagatttct gataagggtg gttttaactg
     9901 ggaattgaga gttaatgaat cggttgtaga taattattta atctacggag atttacacat
     9961 tgataacact agagatttta atattaagct gaatgttaaa gacggtgaca tcatggactg
    10021 gggaatgaaa gactataaag caaacggatt tccagataag gtaacagata tggatggaaa
    10081 tgtttatctt caaactggct atagcgattt gaatgctaaa gcagttggag tccactatca
    10141 gtttttatat gataatgtta aacccgaagt aaacattgat cctaagggaa atactagtat
    10201 cgaatatgct gatggaaaat ctgtagtctt taacatcaat gataaaagaa ataatggatt
    10261 cgatggtgag attcaagaac aacatattta tgtaaatgga aaagaatata catcatttga
    10321 tgatattaaa caaataacag acaagacact aaacattaag attgttgtaa aagattttgc
    10381 aagaaataca accgtaaaag aattcatttt aaataaagat acgggagagg taagtgaatt
    10441 aaaacctcat agggtaactg tgaccattca aaatggaaaa gaaatgagtt caacgatagt
    10501 gtcggaagaa gattttattt tacctgttta taagggtgaa ttagaaaaag gataccaatt
    10561 tgatggttgg gaaatttctg gtttcgaagg taaaaaagac gctggctatg ttattaatct
    10621 atcaaaagat acctttataa aacctgtatt caagaaaata gaggagaaaa aggaggaaga
    10681 aaataaacct acttttgatg tatcgaaaaa gaaagataac ccacaagtaa accatagtca
    10741 attaaatgaa agtcacagaa aagaggattt acaaagagaa gatcattcac aaaaatctga
    10801 ttcaactaag gatgttacag ctacagttct tgataaaaac aatatcagta gtaaatcaac
    10861 tactaacaat cctaataagt tgccaaaaac tggaacagca agcggagccc agacactatt
    10921 agctgccgga ataatgttta tagtaggaat ttttcttgga ttgaagaaaa aaaatcaaga
    10981 ttaagacaaa agctatagaa aaaaatggtt tatgtactga gattagatag tgaggtgatg
    11041 acatagtttt gtgaaaacgg ccatttataa ctcaattatt tagtttactt cacttcacta
    11101 ttgatactat ttggagttat taatggactt agtttagata actaatgaat tgattgaaag
    11161 ggttagtatt gacaatattg gtcatattga ttagaaaata gagtctatca aaatttaaag
    11221 gctaatagag gtgatgagac aatttcaagg aattaagtag cgtttggttg cttaattcct
    11281 ttttatttgg aaggaagttt ttcgtaaccg cccaataacg aagtctattg gacggttacg
    11341 atatgatcac tgacttcgtc agtcttatct acaacctcaa aactgtgttt tgagcaacct
    11401 gcggctagct tcctagttta ctctttgatt ttcattgagt attagaacag aaaaaatgct
    11461 tggagtattt gtttgtgtgt ttatttttat ataacaaact ataaacaaaa caaaaatata
    11521 aaaaaagaga caaaaaagaa caaaaagtaa ttgacaacgg tttcatatag tgttatactt
    11581 atggcataaa gttaatggaa agaagggaaa aacttatggt attagattat ttctttgaca
    11641 aaaaccttgt gttttgctta gaagcggata atcaagaaca tctctttgat caggttgcaa
    11701 ctttattgga agaacgagaa attgtaactc caacttatcg tgaagccttg atcacgcgtg
    11761 aaaagtcatt tccaactggt ttagatatgg aatttctagg aaaggacttg ccaaatgtag
    11821 cgattcctca cacagatatt gttcataatc tagctgagaa agtggtggtt gttcgattag
    11881 aaaaaccagt aacttttcac aatatgatag ctcctgataa ggaagtagaa gtatctctac
    11941 tcttctttat cattaacaat tcaagttcaa gtcaaacgaa cattctggct cagttgatgg
    12001 actttttcac aggaaatggt catcttgaag acctatcaaa aatttctgaa ccagaaaaac
    12061 tttatgctta cattgctgaa gcaaccgctt aatcttgtct attaaaaaat aaaatcggag
    12121 gaaatccaaa tgattaaaat tcttgctgcc tgcggtgcag gtgttaactc aagtcaccaa
    12181 attaaaagtg ctctagaaga agaactttca aaccgtggtt atgatgttca ctgtgatgca
    12241 gtcatggtga aagatgtaaa cgaagacctt atgaaaggtt acgatatctt tacaccaatc
    12301 gctgcaacag accttggttt tgaaccaggt atcccagtta tcgaagctgg gccaatctta
    12361 ttccgtatcc cagcaatgag cgctccagta tttgacaata ttgaagcagc tattaaagaa
    12421 catggattaa gctaattcta atttgttaac attcatataa cataaaaaag ggaggaactg
    12481 ttatggatgc aatctttgac ctaatcggaa aggttttcaa tcccatctta gaaatgggtg
    12541 gacctgtcat catgttgatc attttgacag tattggcttt actttttgga gtgaaattct
    12601 ccaaagcgct tgaaggtggt atcaaacttg ccatcgctct tacaggtatc ggtgctatca
    12661 tcggtatgct aaatagtgct ttctcagcat cacttgcaaa attcgttgaa aacactggta
    12721 tccaattgag tattacagac gttggttggg caccactcgc aacaatcact tggggttctg
    12781 cttggacact atacttcttg ctcatcatgt tgattgtcaa cgtagtgatg cttgctatga
    12841 agaaaaccga tacacttgat gtcgatatct ttgatatctg gcacttgtct atcacaggtc
    12901 tcttgattaa atggtatgct gataacaatg gtgtgagtca aggggtttca ctctttattg
    12961 ctacagcagc tatcgtcctt gtcggtgtgt tgaaaattat caactctgac ttgatgaaac
    13021 ctacatttga tgaccttctt aacgccccaa gttcatcacc aatgacatca actcacatga
    13081 actacatgat gaacccagtt atcatggttt tggataagat ttttgaaaaa ttcttcccag
    13141 gccttgataa atatgacttt gatgctgcta aattgaacaa gaaaatcggt ttctggggat
    13201 ctaaattctt catcggtttc atccttggta tcgttatcgg tattatggga actccacatc
    13261 caattgcagg tgttgcagat gcagataaat ggcgtcttgt tatcaaagga tggttgtctc
    13321 ttggtttgac tgccggtgta tctttggaac tcttctcact tatcggttca tggttcatcg
    13381 cagccgtaga accactatca caaggtatta caaacgttgc tactaaacgt cttcgaggac
    13441 gtaaattcaa tatcggtctt gactggccat tcatcgctgg tcgtgctgaa atctgggctt
    13501 gtgccaacgt acttgcacca atcatgttga ttgaagcagt gcttctttca aaagttggaa
    13561 atggtatctt gccacttgca ggtatcatcg ctatgggtgt tactccagct ctcttggttg
    13621 taactcgtgg taaattgctc cgtatgatta tcttcggaac actcttgttg ccactcttcc
    13681 ttctttcagg tacacttatt gcaccatttg caacagaact tgctaaaggt gtaggtgcct
    13741 tcccagaagg tgtgagccaa actcaattga ttactcactc tactcttgaa ggaccaatcg
    13801 aaaaacttct tggttggaca attggtaaca ctacaactgg tgatatcaaa gcaatccttg
    13861 gtgcagtagt cttccttgta ttctatatcg gtatctttgc ttggtacaga aaacaaatga
    13921 tcaaacgtaa cgaagagtac gcagcaaaag caaaataatg cgctcctata aaatataaac
    13981 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gttgctaaaa acacagtttt
    14041 gaggttgtag ataagactga cgaagtcagc tcaaaacatg gttttgaggt tgtagatgaa
    14101 actgacgaag tcagtaatca tatctacggc aaggcgacgc tgacgaagtt tgaattggat
    14161 tttcgcagag tgtaaattgt tgaaactagg ttgtcatacc atgtatacca cttgggcttt
    14221 ggtagtagct aactgcacta aatataatat aaggagggtt ttatggggaa aggccattgg
    14281 aatcggaaaa gagtttatag cattcgtaag tttgctgtgg gagcttgctc agtaatgatt
    14341 gggacttgtg cagttctatt aggaggaaat atagctggag aatctgtagt ttatgcggat
    14401 gaaacactta ttactcatac tgctgagaaa cctaaagagg aaaaaatgat agtagaagaa
    14461 aaggctgata aagctttgga aactaaaaat gtagttgaaa ggacagaaca aagtgaacct
    14521 agttcaactg aggctattgc atctgagaag aaagaagatg aagccgtaac tccaaaagag
    14581 gaaaaagtgt ctgctaaacc ggaagaaaaa gctccaagga tagaatcaca agcttcaagt
    14641 caagaaaaac cgctcaagga agatgctaaa gctgtaacaa atgaagaaat gaatcaaatg
    14701 attgaagaca ggaaagtgga ttttaatcaa aattggcact ttaaactcaa tgcaaattct
    14761 aaggaagcca ttaaacctga tgcagacgta tctacgtgga aaaaattaga tttaccgtat
    14821 gactggagta tctttaacaa tttcgatcat gaatctcctg cacaaaatga aggtggacaa
    14881 ctcaacggtg gggaagcttg gtatcgcaag actttcaaac tagatgaaaa agacctcaag
    14941 aaaaatgttc gccttacttt tgatggcgtc tacatggatt ctcaagttta tgtcaatggt
    15001 cagttagtgg ggcattatcc aaatggttat aaccagttct catatgatat caccaaatac
    15061 cttcacaaag atggtcgtga gaatgtgatt gctgtccatg cagtcaacaa acagccaagt
    15121 agccgttggt attcaggaag tggtatctat cgtgatgtga ctttacaagt gacagataag
    15181 gtgcatgttg agaaaaatgg gacaactatt ttaacaccaa aacttgaaga acaacaacat
    15241 ggcaaggttg aaactcatgt gaccagcaaa atcgtcaata cggacgacaa agaccatgaa
    15301 cttgtagccg aatatcaaat cgttgaacga ggtggtcatg ctgtaacagg cttagttcgt
    15361 acagcgagtc gtaccttaaa agcacatgaa tcaacaagcc tagatgcgat tttagaagtt
    15421 gaaagaccaa aactctggac cgttttaaat gacaaacctg ccttgtacga attgattacg
    15481 cgtgtttacc gtgacggtca attggttgat gctaagaagg atttgtttgg ttaccgttac
    15541 tatcactgga ctccaaatga aggtttctct ttgaatggtg aacgtattaa attccatgga
    15601 gtatccttgc accacgacca tggggcgctt ggagcagaag aaaactataa agcagaatat
    15661 cgccgtctca aacaaatgaa ggagatggga gttaactcta tccgtacaac ccacaaccct
    15721 gctagtgagc aaaccttgca aatcgcagca gaactaggtt tactcgttca ggaagaggcc
    15781 tttgatacgt ggtatggtgg caagaaacct tatgactatg gacgtttctt tgaaaaagat
    15841 gccactcacc cagaagctcg aaaaggtgaa aaatggtctg attttgacct acgtaccatg
    15901 gtcgaaagag gcaaaaacaa ccctgctatc ttcatgtggt caattggtaa tgaaataggt
    15961 gaagctaatg gtgatgccca ctctttagca actgttaaac gtttggtcaa ggttatcaag
    16021 gatgttgata agactcgcta tgttaccatg ggagcagata aattccgttt cggcaatggt
    16081 agcggagggc atgagaaaat tgctgatgaa ctcgatgctg ttggatttaa ctattctgaa
    16141 gataattaca aagcccttag agctaagcat ccaaaatggt tgatttacgg ttcagaaaca
    16201 tcatcagcaa cccgtacacg aggaagttac tatcgccctg aacgtgaatt gaaacatagc
    16261 aatggacctg agcgtaatta tgaacagtca gattatggaa atgatcgtgt gggttggggg
    16321 aaaacagcaa ccgcttcatg gacttttgac cgtgacaacg ctggctatgc tggacagttt
    16381 atctggacag gtacggacta tattggtgaa cctacaccat ggcacaacca aaatcaaact
    16441 cctgttaaga gctcttactt tggtatcgta gatacagccg gcattccaaa acatgacttc
    16501 tatctctacc aaagccaatg ggtttctgtt aagaagaaac cgatggtaca ccttcttcct
    16561 cactggaact gggaaaacaa agaattagca tccaaagtag ctgactcaga aggtaagatt
    16621 ccagttcgtg cttattcgaa tgcttctagt gtagaattgt tcttgaatgg aaaatctctt
    16681 ggtcttaaga ctttcaataa aaaacaaacc agcgatgggc ggacttacca agaaggtgca
    16741 aatgctaatg aactttatct tgaatggaaa gttgcctatc aaccaggtac cttggaagca
    16801 attgctcgtg atgaatctgg caaggaaatt gctcgagata agattacgac tgctggtaag
    16861 ccagcggcag ttcgtcttat taaggaagac catgcgattg cagcagatgg aaaagacttg
    16921 acttacatct actatgaaat tgttgacagc caggggaatg tggttccaac tgctaataat
    16981 ctggttcgct tccaattgca tggccaaggt caactggtcg gtgtagataa cggagaacaa
    17041 gccagccgtg aacgctataa ggcgcaagca gatggttctt ggattcgtaa agcatttaat
    17101 ggtaaaggtg ttgccattgt caaatcaact gaacaagcag ggaaattcac ccttactgct
    17161 cactctgatc tcttgaaatc tagtcaagtc actgtcttta ctggtaagaa agaaggacaa
    17221 gaaaagactg ttttggggac agaggtgcca aaagtacaga ccattattgg agaggcacct
    17281 gaaatgccta ccactgttcc gtttctatac agtgatggta gtcgtgcaga acgtcctgta
    17341 acctggtctt cagtagatgt gagcaagcct ggtattgtaa cggtgaaagg tatggctgac
    17401 ggacgagaag tagaagctcg tgtagaagtg attgctctta aatcagagct accagttgtg
    17461 aaacgtattg ctccaaatac tgacttgaat tctgtagaca aatctgtttc ctatgttttg
    17521 actgatggaa gtgtacaaga gtacgaagta gatagctggg agattacgga agtagataaa
    17581 gccaaacttt cagtagctgg atcacgtatt caaatgactg gtcagttagc tggagaaact
    17641 attcatgcaa cccttgtggt agaagaagga aatgctgcag cacctgtagt gccaactgtt
    17701 actgttggag gtgaagcagt aacaggtctt actagtcgac aaccaatgca atatcgtact
    17761 ctatcttatg gtgcccaatt gccagaagtc acagcaagtg ctgaaaatgc tgatgtgaca
    17821 gttcttcaag caagcgcagc aaacggcatg cgtgcaagca tatttgttca gcctaaagat
    17881 ggtggccctc ttcaaaccta tgcaattcaa ttcctagaag aagcaccaaa aattgctcac
    17941 ttgagcttgc aagtggaaaa agctgacagt ctcaaagaag accaaactgt caaattgtcg
    18001 gttcgagctc actatcaaga tggaacgcaa gctgtattac cagctgataa agtaaccttc
    18061 tctacaagtg gtgaagggga agtcgcaatt cgtaaaggaa tgcttgagtt gcataagcca
    18121 ggagcagtca ctctcaaagc ggaatatgag ggagctaaag gccaagttga actcactatc
    18181 caagccaata ctgagaagaa gattgcgcaa tctatccgtc ctgtaaatgt agtcacagat
    18241 ttgcatcaaa aacctactct tccaacaaca gtaacggttg agtatgacaa aggtttccct
    18301 aaagctcaca aagtcacttg gcaagctatt ccgaaagaaa aactagactc ctatcaaaca
    18361 tttgaagtac taggtaaagt tgaaggaatt gaccttgaag cgcgtgcaaa agtctctgta
    18421 gaaggtatcg tttcagttga agaagtcagt gtgacaactc caatcgcaga agcaccacaa
    18481 ttaccagaaa gtgttcggac atatgattca aatggtcacg tttcatcagc taaggttgca
    18541 tgggatgcga ttcgtccaga gcaatacgct aaggaaggtg tctttacagt taatggtcgc
    18601 ttagaaggta ctcaattaac aactaaactt catgttcgcg tatctgctca aactgagcaa
    18661 ggtgcaaaca tttctgacca atggaccggt tcagaattgc cacttgcctt tgcttcagac
    18721 tcaaatccaa gcgacccagt ttcaaatgtt aatgacaagc tcatttccta caataaccaa
    18781 ccagccaatc gttggacaaa ctggaatcgt actaatccag aagcttcagt cggtgtccta
    18841 ttcggagatt caggtatttt gagcaaacgt tcagttgata acttaagcgt tggcttccat
    18901 gaagaccatg gagttggtgc accgaagtct tatgtgattg agtattatgt tggtaagact
    18961 gtcccaacag ctcctaaaaa ccctagtttt gttggtaatg aggaccatgt ctttaatgat
    19021 tctgccaact ggaaaccagt tactaatcta aaagcccctg ctcaactcaa ggctggagaa
    19081 atgaaccact ttagctttga taaagttgaa acctatgctg ttcgtattcg catggtgaga
    19141 gcagacaaca aactaggaac gtctatcaca gaggtacaaa tctttgcgaa acaagttgcg
    19201 gcagccaagc aaggacaaac aagaatccaa gttgacggta aagacttagc aaacttcaac
    19261 cctgatttga cagactacta ccttgagtct gtagatggaa aagttacggc agtcacagca
    19321 agtgttagca acaatggcct cgctaccgtc gttccaagcg ttcgtgaagg tgagccggtt
    19381 cgtgtcatcg cgaaagctga aaatggcgac atcttaggag aataccgtct gcacttcact
    19441 aaggataaga acttactttc tcataaacca gttgctgcgg ttaaacaagc tcgcttgcta
    19501 caagtaggtc aagcacttga attgccgact aaggttccag tttacttcac aggtaaagac
    19561 ggctacgaaa caaaaaacct gacagttgaa tgggaagaag ttccagcgga aaatctgata
    19621 aaagcaggtc aatttaccgt tcgaggccat gtccttggta gtgatcttgt tgctgaggtc
    19681 actgtacgag tgacagacaa actaggcgaa gctctttcag ataaccctaa ctatgatgaa
    19741 aacagtaacc aggcctttgc ttcagcaacc aatgatattg acaaaaactc tcatgaccgc
    19801 gttgactatc tcaatgacgg agatcattca gaaaatcgtc gttggacaaa ctggtctcca
    19861 acaccatctt ctaatccaga agtatcagcg ggtgtgatct tccgtgaaaa tggtaagatt
    19921 gtagaacgga ctgttgctca agccaaactt cacttctttg cagatagtgg tacggatgca
    19981 ccaactaaac tcgttttaga acgctatgtc ggtccagagt ttgaagtgcc aacctactat
    20041 tcaaactacc aagcctacga cgcagaccat ccattcaaca atccagaaaa ttgggaagct
    20101 gtgccttatc gtgcggataa agacatcgca gctggtgatg aaatcaacgt aacatttaaa
    20161 gctgtcaaag ccaaagctat gagatggcgt atggagcgta aagcagataa gagcggtgtt
    20221 gcgatgattg agatgacctt ccttgcacca agtgaattgc ctcaagaaag cacgcaatcg
    20281 aagattcttg tagatggaaa agaacttgct gatttcgctg aaaatcgtca agactatcaa
    20341 attacctata aaggtcaacg gccaaaagtc tcagttgaag aaaacaatca agtagcttca
    20401 actgtggtag atagtggaga agatagcctt ccagtacttg ttcgcctcgt ttcagaaagt
    20461 ggaaaacaag tcaaggaata ccgtatccag ttgactaagg aaaaaccagt ttctgagaag
    20521 acagttgctg ctgtacaaga agatcttcca aaactcgaat ttgttgaaaa agatttggcc
    20581 tacaagacag ttgagaaaaa agattcaaca ctgtatctag gtgaaactcg tgtagaacaa
    20641 gaaggaaaaa ctggtaaaga acgtatcttt acagcgatta atcctgatgg aagtaaggaa
    20701 gaaaaactcc gtgaagtggt agaagctccg acagaccgca tcgtcttggt tggaaccaaa
    20761 ccagtagctc aagaagctaa aaaaccacaa gtgtcagaaa aagcagatac aaaaccaatt
    20821 gattcaagtg aagctagtca aactaataaa gcccagttac caaatacagg tagtgcggca
    20881 agccaagcag cagtagcagc aggtttagct cttctaggtt tgagtgcagg attagtagtt
    20941 actaaaggta aaaaagaaga ctagaaattt tgataccttc tttatcatta aagaccaaag
    21001 aaaaactctt gtcctaaata gaagataaag agtctggaac aaaatagttc tcaaccacaa
    21061 aaaagctaga tatttccaat tgcggaactc tagcttttta attttgagtc gttctcttat
    21121 tgtatagtag attgaaacta gagtagtaca cttctacttc taaaacattg ttagaaatcg
    21181 atttgactgt ccttatcgat ttgtcctgtt cttatttcat ttcactatgt tttaggaggt
    21241 tattggccat aagtaccaat cccatgtcaa ttctcacttg acgcttgcct ctcagattac
    21301 atctcttgta acccaaacaa gcctttatct gcccaaagac aggttctaca tcaatcttgc
    21361 gttgagcgaa aatctgtcta tcttggggag ataaaagcgc ctgacattct ttagctttca
    21421 agttttgata gcgttcgttc atatacaatc ccttttgagg ggctgattca ggttcatcag
    21481 cgtagtaaac cttgatttcc tgttgaaagt ctgtctgtgt tttctggtac ttgatatggt
    21541 gaaaacgata gcaccagcca tcaggatgta tgtagctatc ctccttgtca ttatagtgcc
    21601 aattcgctaa gtttttagct gactgtttat accctctctt ttgttcctta tcaaacatgg
    21661 catatttaat cagaagggga gtgatttctt cttgaaaata gacttgtatc tgttcttgaa
    21721 gtttggcgga gaatttctct gtcgttttct tccacacaaa actatacttg ttggcattgg
    21781 attcaatctt agttccgtca ataaacaaac aatctaaggt cactaactct tccatttttc
    21841 aatttttcga ccagagaaaa tcccttgtga ataggcaaat agaagagtag atacaagcat
    21901 tttagggtga taagacgggc gaccaaaggc atgataggag gtgtagaagt gacgttcctc
    21961 caaggtattc accacttttt caatagtaaa gacgagatgg tcttgtggta agaaggaact
    22021 gatttctagt ggtaaagttg tttgatttgt gttatagtga atatgcatgg gatagccttt
    22081 ctaaatggtt tattaagcaa ttctatttta ccaagactat cgtaaccatg caaaaaagca
    22141 acggcaaatc cgttgccttt tttggatata agagactatt gtcccagact cttttctttg
    22201 tataaaattg tatagtgtta ttgtctatac tattttgtag agaaagcaaa aatccctaga
    22261 aaatgcttag ggattcgact atttcattaa gaacaattca acaatcatct ctatatacat
    22321 gataagggtt aataaaaatc ctgtacgcca gaagaatttg atgaatttag gatagtaaaa
    22381 gctgcgtttt tttaaaagga agaaaaagac gagaataatg gctaggaacg agagggctag
    22441 ccccagtcta gggaggaaat tatgggtaaa ggttttagct gtaatcaagt aatactcaaa
    22501 taccaagact ggaaaagcca aatccgcaaa gtttcgtcct agttttttta atctaaaaag
    22561 tttggttagg ataatgcaga cgactaaggt cagtatcaat aataaaatag atgctaattt
    22621 cattaaaatc atacccatat tgtatcataa aaaaaggcta atggaaacga gaaacagagg
    22681 aatttatagg aaagtcaggc ttttgagatt gtgggtgatt tttgttataa tgaaagttat
    22741 aaaatcttat gataccttga atgattatta tcgaaaactc tttggagaaa agacttttaa
    22801 agtccctatt gatgcgggat ttgactgtcc caatcgtgat ggaactgtgg ctcatggagg
    22861 ctgtactttt tgtacggttt ccggttctgg agatgccatt gtagccccag atccgcctat
    22921 ccgtgagcaa ttttataagg aaattgactt tattcatcgt aagtggccag atgttcagaa
    22981 gtatctggtt tattttcaaa attttaccaa cacccatgaa aaggtggaag ttattcgaga
    23041 gcgttatgaa caggctatca atgagccagg tgtggtagga atcaatattg gaacgcgccc
    23101 agactgttta ccagacgaaa ccatcgaata tttggctgag ttatcggagt gcatgcatgt
    23161 gacggttgaa ttgggcttgc agactactta tgaagcaacc tctgacctga ttaaccgtgc
    23221 gcattcttat gaattgtagg tggaaacggt caagcgtttg agaaagtatc caaaaattga
    23281 gattgtttcc catttgatca atggtttgcc tggtgaaacc catgagatga tggttgaaaa
    23341 tgtccgccgt tgtgtcacgg ataacgatat tcaagggatt aaactgcatt tgctccatct
    23401 tatgacaaat actcgtatgc aacgagatta ccatgaggga cgtttacaat tgatgagtca
    23461 ggacgaatat gtcagggtca tctgtgacca actggaaatt attcccaaac atatcgtcat
    23521 ccatcgaatt acaggagatg cgcctaggga tatgctgatt ggtcctatgt ggagcctcaa
    23581 taaatgggaa gtcctcaaca gcattgagat ggagatgaga cgtcgtggaa gtgttcaagg
    23641 atgcaaggct gtaaaacagg agtttgaaaa tgaaaagacc acttgagatg gcacatgatt
    23701 ttttggctga ggtcgtgaca aaagaggatg tcgtagtgga tgcgactatg ggaaatggtc
    23761 atgacacgct ttttttagcc aagctagcca agcaagtcta tgcctttgat attcagaagc
    23821 aagccttgga aaagacccaa gagcgtttgc atcaggctgg cttgacaaat gcccagttaa
    23881 tcttgcaagg ccatgagaca ctggaccagt ttgtgacaaa agctaaggca gggattttta
    23941 atttgggcta tttgccgtca gctgataagt ctgtcatcac ccgaccgcag acaacgattg
    24001 aggcattaga aaagctatgt ggcttacttg tcaaaggtgg acgaattgct attatgattt
    24061 actatggtca tgaaggaggc gacctcgaga gagatgctgt cttggatttt gtgatccagt
    24121 tgaaccaaca agagtacaca gctgccattt accgaacttt aaaccaagtc aacaacccgc
    24181 cgtttttagt gatgattgaa aaattagaga gatacagaca tggataaaca atacctacac
    24241 gaaaagctgg atgccatgcg ccagaatttt gttgaatcaa cctaccacga acgagcggtg
    24301 ggcgtgctag accaagcgca tatgagcaaa aaaatgctta aaatcaagaa aaaattagtt
    24361 gctcttgaaa tggaacggtg ccagagaaaa attgagcaca aagactgttc caagattgac
    24421 caaaaaatca aagagcagaa ggagatattt gaatcctgtt gtaaaaaaga ttaaggagga
    24481 cgtgcgtgga attactgatt tacctcatcc tatttttact ggtcttgatt gtctcaagta
    24541 caaccaataa gctcctaccc tttttgcctc tccctttggt gcagattctt ttgggaattg
    24601 tgattggtct ctttttaccc aatactgact ttcaccttaa tacggagttg tttttggcac
    24661 tggttatcgg ccccttgctt ttccgagagg ctgaagaagc agatgttacg gctattttaa
    24721 aacactggcg aatcattgtt tatctcatat ttccagtgat ttttatctcg accctgagtt
    24781 tgggtggctt ggcccatctt ctttggttca gccttccctt ggcagcttgc ttggctgttg
    24841 gggcagccct tggtcctacg gacttggtgg cctttgcctc tctttcggag cgttttagct
    24901 ttcctaagcg cgtgtccaat attcttaagg gcgaaggact cttgaatgat gcttctggtt
    24961 tggtggcttt tcaggtagct ttgacagctt ggacaactgg agctttttct ctggggcaag
    25021 ctagcagttc actcatcttt tcaatcctag gcggtttttt aattggattt ttaacagcta
    25081 tgaccaaccg cttcctccat accttcttgc taagtgtgcg cgcaacggat attgccagtg
    25141 aacttttatt agagttgagt ttgcctctag tgaccttctt tctggcagaa gaagtccatg
    25201 tttcagggat tattgccgtc gtagttgctg gaattttaaa ggcaagtcgc ttcaagaaaa
    25261 tcacgctcct cgaagcccaa gtggatacgg tgaccgagac ggtctggcat acagtgacct
    25321 ttatgctcaa cggttctgtc tttgtgattt tagggatgga gttggaaatg atagcagaac
    25381 ctatcttgac caatccaatc tataatcctc tacttttatt gctatctctc atcgccctta
    25441 cctttgtcct ctttgtcatt cgttttatta tgatctatgg ctattatgcc tatagaaccc
    25501 gacgcctcaa gaaaaagcta aataagtata tgaaggacat gtttctcttg accttttcag
    25561 gtgttaaggg aacggtgtcg attgctacga ttctcttgat accaagtaat ctagaacagg
    25621 agtatcctct cttgcttttc cttgttgcag gtgtgacgct tgtcagcttt ttaacaggtc
    25681 tcttggtctt gcctcatctt tctgatgaag aggaagaaag caaggattat ctcatgcata
    25741 tcgccatttt gaatgaagta acgctagagt tggaaaaaga gttggaagac accagaaata
    25801 aacttcccct ctatgcggct attgacaatt atcatggacg tattgaaaat ctcattttaa
    25861 gccaagaaaa ccaggatgat caagaagact gggctgcttt gaaactcttg attcttagta
    25921 ttgaaagtga tggtttggaa caggcctatg aagaggggaa cattagcaat cgtgcttacc
    25981 gagtttacca acgttatctg aaaaatatag aacaaggaat caatcgtaaa cttgcctcaa
    26041 gactgaccta ttattttctt gtttccttga ggattttacg ttttctcctt catgaagttt
    26101 ttactcttgg aaagaccttc cgtagctgga aggacaagga gcaaagccgt ctccgtgctc
    26161 ttgattatga ccaaattgca gagctctatc ttgccaatac agagatgatt attgaaagtt
    26221 tggaaaacct gaagggagtc tacagacgct ctttgattag ttttatgcag gagtctcgtc
    26281 ttcgagaaac agctattatc agcagtggtg cctttgtcga acgggttatc aatcgtgtca
    26341 aacccaacaa tatcgatgaa atgctgagag gctattatct ggagcgcaag ttgattttcg
    26401 aatacgaaga aaaacgattg attacgacta agtatgccaa gaaattacga caaaatgtaa
    26461 ataacttaga gaactattcc ttgaaggaag ctgccaatac cctaccgtat gatatggtgg
    26521 aattggtaag aagaaattag ttaatactct tcgaaaatct cttcaaacca cgtcagcgtc
    26581 gccttaccgt atgtatgtga ctgacttcgt cagtcttatc tacaacctca aaacagtgtt
    26641 ttgagcagct tgcggctagc tttctagttt gctctttgat tttcattgag tataagatta
    26701 taagtgaagg agtatgacat gaaaaagtgg tggaaagagc tgatagacaa acctttatta
    26761 aaagcttttt tgcattatta tcaagcatca gatagtgagt tgaccagtgt cgcagtagcc
    26821 tactattggt tgatttcgat tttccccctg cttttggtgg tggtcaatat cctcccctat
    26881 tttcagattc ctgtgggaga atttctgggc tttatgaaag acgtcctgcc cccaagcctc
    26941 tatgaaggtg tggaaaaaat agccagagaa gtcttgacgc aaccttcaac aggtttattg
    27001 agtttttctg ttttatcggc gttatggagt ttttcaaaat ctatgaattt cttgcaaaaa
    27061 gcttttaaca aggcttatgg cgtcgaaaag agtcgtggac ttatttccca tcagatgcta
    27121 agtctcctag tcagttttgg cttgcagctc ctctttgcgt ttgccttgtt tttgatctta
    27181 tttggtcaga tgattttggc tttacttgct cattattgga caaaagatgg cattatctat
    27241 caggctttac aagggttggc aggtcctctg atttacgccc tcctctttgc tatcttggtc
    27301 atgctttatt attttcttcc caatctatct aacaggaaaa ttagctatac cctaccaggc
    27361 agtgcctttg ttctcttagt gattttaggt ttactaactc tgttctctag ttatctcaat
    27421 tactatgtcc atcatttggt ggatgtccga attttaggtt ccgttcttct tgttgttatg
    27481 atgttttggt ttatcttgat tgctaaaatt gttatcctag gcgcggttat caatgccagt
    27541 atgcagagtt tgaaagatcc ggtctttaaa aaagactaac tatttatcca ttataaaagc
    27601 gcatagtatc aagactttat agaaccttga tactatgcgc ttttgtgctt tgacagtttt
    27661 ttgtatagtt tttgtccaag atttctaaat catctgatta aattcctatt ttcccctatc
    27721 attgtccctg ttttttcgaa aatggaagga gtataataaa tctatcaata aaatgatagg
    27781 aggaacttta tgggtcatat tttctttttt ctaagtgtct ttttggcagg gattctatcc
    27841 ttcttttctc cttgtatctt acctttgtta ccggtctata caggagtgtt actagatgat
    27901 aaggatggtg ctcaggcttc tagcggcaaa ttttcaatct cagttactag tttattacga
    27961 actctggcct ttatagcagg aatttccttt atatttattt tgttgggcta tggagctggt
    28021 tttttaggcg atttgcttta tgcttcttgg ttccaatatc ttactggggc aattattatc
    28081 cttcttggtt tgcaccaaat ggagattcta cactttaagg ggctttataa ggaaaagaga
    28141 ctacaactgc aaggacaggg gcaaaatggt aagggctata gtcaggcatt tttattgggc
    28201 ttgaccttta gttttgcttg gacgccttgc gtggggccgg ttctggggtc tgttttggcc
    28261 ttggcggctt caggtggttc aggagcttgg cagggagctg gtctcatgtt ggtgtatacg
    28321 ctgggcttgg cgctaccatt cttgcttcta gctctgacct ctagttatgt tttgaaacat
    28381 ttccgaaaac ttcatcccta tctcggaatc ctcaaaaaag tgggtggttt tctcattatt
    28441 gtgatgggac tcttggttct gtttggaaat gcttcaattt taagtcaatt atttgaataa
    28501 aatggaaagg aatatcaata tgaaaaaatg gcaaacatgt gttcttggag caggttcgct
    28561 cctttgtttg acggcttgtt caggcaagtc cgtgactagt gaacaccaaa cgaaagatga
    28621 aatgaagacg gagcagacag ctagtaaaac aagcgcagct aaagggaaag aggtggctga
    28681 ttttgaattg atgggagtag atggcaagac ctaccgttta tctgattaca agggcaagaa
    28741 agtctatctc aaattctggg cttcttggtg ttccatctgt ctggctagtc ttccagatac
    28801 ggatgagatt gctaaagaag ctggtgatga ctatgtggtc ttgacagtag tgtcaccagg
    28861 acataaggga gagcaatctg aagcggactt taagaattgg tataagggat tggattataa
    28921 aaatctccca gtcctagttg acccatcagg caaacttttg gaaacttatg gtgtccgttc
    28981 ttacccaacc caagccttta tagacaaaga aggcaagctg gtcaaaacac atccaggatt
    29041 catggaaaaa gatgcaattt tgcaaacttt gaaggaatta gcctaggagg tgtcttatga
    29101 atgataagtt aaaaatcttc ttgttgctag gagtattttt tctagccata accggtttct
    29161 atgttctatt gatacgaaat gcagggcaga cagatgcctc gcaaattgaa aaggcggcag
    29221 ttagccaagg aggaaaagca gtgaaaaaaa cagaaattag taaagacgca gacttgcacg
    29281 aaatttatct agctggaggt tgtttctggg gagtggagga atatttctca cgcgttcccg
    29341 gggtgacgga tgccgtttca ggctatgcaa atggtagagg agaaacaacc aagtacgaat
    29401 tgattaacca aacaggtcat gcagaaaccg tccatgtcac ctatgatgcc aagcaaattt
    29461 ctctcaagga aatcatgctt cactatttcc gcattatcaa tccaaccagc aaaaataaac
    29521 aaggaaatga tgtggggacc cagtaccgta ctggtgttta ttacacagat gacaaggatt
    29581 tggaagtgat taaccaagtc tttgatgagg tggctaagaa atacgatcaa cctctagcag
    29641 ttgaaaagga aaacttgaag aattttgtgg tggctgagga ttaccatcaa gactatctca
    29701 agaaaaatcc aaatggctac tgccatatca atgttaatca ggcggcctat cctgtcattg
    29761 atgccagcaa atatccaaaa ccaagtgatg aggaattgaa aaagaccctg tcacctgagg
    29821 agtatgcagt tacccaggaa aatcaaacag aacgagcttt ctcaaaccgt tactgggata
    29881 aatttgaatc cggtatctat gtggatatag caactgggga acctctcttt tcatcaaaag
    29941 acaaatttga gtctggttgt ggctggccta gttttaccca acccatcagt ccagatgttg
    30001 tcacctacaa ggaagataag tcctacaata tgacgcgtat ggaagtgcgg agccgagtag
    30061 gagattctca ccttgggcat gtctttacgg atggtccaca ggacaagggc ggcttacgtt
    30121 actgtatcaa tagcctctct atccgcttta ttcccaaaga ccaaatggaa gaaaaaggct
    30181 acgcttattt actagattat gttgattaat actcttcgaa aatctcttca aaccacgtca
    30241 gcgtcgcctt accgtatgta gggttactga cttcgtcagt tttatctaca acctcaaagc
    30301 tatactttga gctgacttcg tcagttttat ttacaacctc aaagctatac tttgagaaac
    30361 ctgtggctat cttcctagtt tactttttga tttttattga gtataagagg tctttcctaa
    30421 gcagttagag gagaattttg ctatactgat actagtaagt gacaaaggag agaagcatga
    30481 cctacacaat cttaatcgta gaagatgaat atctggtaag acaaggtttg actaaactgg
    30541 tcaatgtagc agcctacgat atggaaatca tcggtcaggc tgaaaatgga aggcaggctt
    30601 gggaattgat ccaaaagcag gtgccagata tcattttaac cgatatcaac atgcctcatc
    30661 taaatggcat ccagttggcc agtctggtac gagaaaccta tcctcaggtt catttggtct
    30721 ttttaacagg ttacgatgat tttgattatg ccttgtctgc tgtcaaacta ggtgtggacg
    30781 actacctgct caaacccttt tctcgtcagg atattgagga aatgttgggg aaaatcaaac
    30841 aaaaactaga caaggaagag aaagaagagc agttacaaga tttattgact aataggtttg
    30901 aaggaaacat ggcccagaaa atccagtctc atctggctga tagccaattt agtttaaagt
    30961 ctttagccag tgacttaggt tttagtccga cctatctgag ttccttgatt aagaaagagt
    31021 tgggcttgcc ttttcaggat tatctggtga gagaacgtgt taaacaagcc aagctcttgc
    31081 ttttaactac agatctgaag atttatgaga tcgcagagaa ggttggtttt gaagatatga
    31141 actattttac ccaacgtttt aagcagattg caggtgtgac acctcgtcag tttaagaagg
    31201 gagaagaccg atgaagcgtt cttctctttt agttagaatg gttatttcca tctttctggt
    31261 ctttctcatt ctcctagctc tggttggaac tttctactat caatcaagtt cttcagccat
    31321 tgaggccacc attgagggca acagccaaac gaccatcagc cagactagcc actttattca
    31381 gtcttatatc aaaaaactag aaaccacctc gactggtttg acccagcaga cggatgttct
    31441 ggcctatgct gagaatccca gtcaagacaa ggtcgaggga atccgagatt tgtttttgac
    31501 catcttgaag tcagataagg acttgaaaac tgttgtgctg gtgaccaaat ctggtcaggt
    31561 catttctaca gatgacagtg tgcagatgaa aacttcctct gatatgatgg ctgaggattg
    31621 gtaccaaaag gctattcatc agggagctat gcctgttttg actccagctc gtaaatcaga
    31681 tagtcagtgg gtcatttctg tcactcaaga acttgttgat gcaaagggag ccaatcttgg
    31741 tgtgcttcgt ttggatattt cttatgaaac tctggaagcc tatctcaatc aactccagtt
    31801 ggggcagcag ggctttgcct tcattatcaa tgaaaaccat gaatttgtct accatcctca
    31861 acacacagtt tatagttcgt ctagcaaaat ggaggctatg aaaccctaca tcgagacagg
    31921 tcagggttat actcctggtc acaaatccta cgtcagtcaa gagaagattg caggaactga
    31981 ttggacggta cttggcgtgt catcattgga aaagttagac caggttcgga gtcagctctt
    32041 gtggaccttg cttggggcca gtgtcacatc tcttcttgtc tgtctctgct tagtgtggtt
    32101 cagtcttaaa cgctggattg ctcctttgaa ggatttgaga gaaaccatgt tggaaattgc
    32161 ttctggtgct caaaatcttc gtgccaagga agttggtgcc tatgaactga gagaagtaac
    32221 tcgccaattt aatgccatgt tggatcagat tgatcagttg atggtagcta ttcgtagcca
    32281 ggaagaaacg acccgtcagt accaacttca agccctttcg agccagatta atccacattt
    32341 cctctataac actttggaca ccatcatctg gatggctgaa tttcatgata gtcagcgagt
    32401 ggtgcaggtg accaagtcct tggcaaccta tttccgcttg gcgctcaatc aaggcaagga
    32461 cttgatttgt ctctctgacg aaatcaatca tgtccgccag tatctcttta tccagaaaca
    32521 acgctatgga gataagctgg aatacgaaat taatgaaaat gttgcctttg ataatttagt
    32581 cttacccaag ctggtcctac aaccccttgt agaaaatgct ctttaccatg gcattaagga
    32641 aaaggaaggt cagggccata ttaaactttc tgtccagaaa caggattcgg gattggtcat
    32701 ccgtattgag gatgatggcg ttggcttcca agatgctggt gatagtagtc aaagtcaact
    32761 caaacgtggg ggagttggtc ttcaaaatgt cgatcaacgg ctcaaacttc attttggagc
    32821 caattaccag atgaagattg attctagacc ccaaaaagga acgaaagttg aaatatatat
    32881 aaatagaata gaaactagct aactcccagt caattctggg agttttatgc gtaattgggc
    32941 aaactttcta ggttgtctat cttgctaaaa acaagaaaaa acggtatgat agaagagtga
    33001 caacagaggt aacagagatg aacgagacac agattcaaag agaaacacgt caggtagtgg
    33061 aagatgtttt agaaaagacc aatttgaaac agggggccct ttttgtttta ggtctatctt
    33121 ctagtgaggt gctaggtggt cagattggga aagaatccag tcaagagatt ggtgagctga
    33181 tagtggagac tatcttgggt attctaggta gtagaggtat ccatttagca gttcaaggtt
    33241 gtgagcatgt caatcgggct ctcgttgttg aacgtcaggt ggcagagcag tttggtctgg
    33301 aaattgtcag tgtccatcct actcttcatg caggaggttc ggggcagttg gcagccttta
    33361 agtttatgca ggatccagtt gaggttgaat ttatcaaggc tcatgctgga ttggatatcg
    33421 gagacactgc aattggcatg catgtcaagc atgttcaggt tccgattcgc cctattttga
    33481 gagagattgg tcatgcccat gtaacggcac tggctagtcg tccaaaatta atcggaggtg
    33541 cgcgtgcgca ctatccgcaa gatgctatta gaaagacctg agaatgaata aaggagataa
    33601 aagtgtttaa aaaagaccgt ttttcaattc gtaagattaa gggagttgta ggctctgtat
    33661 ttcttggaag ccttttgatg gctccttctg tagtggacgc agccacctat cactatgtaa
    33721 ataaagagat tatttcacaa gaagctaaag atttaattca gacaggaaag cctgacagga
    33781 atgaagttgt atatggtttg gtgtatcaaa aagatcagtt gcctcaaaca gggacagaag
    33841 catctgtttt gacagctttt ggttatctat caggtgacat cctcaaaacg cttggcttgg
    33901 acactgtttt agaagaaacc tcagcaaaac ctggagaggt gactgtagtc gaagttgaga
    33961 ctcctcaatc aacaacaaat caggagcaag ctaggacaga aaaccaagta gtagagacag
    34021 aggaagctcc aaaagaagaa gcacctaaaa cagaagaaag tccaaaggaa gaaccaaaat
    34081 cggagataaa acctactgac gacacccttc ctaaagtaga agaggggaaa gaagattcag
    34141 cagaaccagc tccagttgaa gaagtaggtg gagaagttga gtcaaaacca gaggaaaaag
    34201 tagcagttaa gccagaaagt caaccatcag acaaaccaac agaggaacca aaagttgaac
    34261 aagtaggtga accagtcgag ccaagtgaag acgaacaggc accaacggca ccagttgagc
    34321 cagaaaagca accagaagct cctgaagaag agaaggctgt agaggaaaca ccgaaaccag
    34381 aagataaaat aaagggtatt ggtactaaag aaccagttga taaaagtgag ttaaataatc
    34441 aaattgataa agctagttca gtttctccta ctgattattc tacagcaagt tacaatgatc
    34501 ttggacctgt tttagaaact gcaaaaggtg tctatgcttc agagcctgta aaacagcctg
    34561 aggtaaatag tgagacaaat aaacttaaaa cggctattga cgctctaaac gttgataaaa
    34621 ctgaattaaa caatacgatt gcagatgcaa aaacaaaggt aaaagaacat tacagtgata
    34681 gaagttggca aaacctccaa actggggtta cagaagctga aaaagttgca gctaatacag
    34741 atgctaaaca aagtgaagta aattctgaga ctgcaagtct taaaacagca atttctagat
    34801 taaatacaga taaagttgaa ctcgaaaatc aacttaagat tgcacaggga aaaactgaaa
    34861 ctgatttcag catggaatct tggactgttt tgagtacagc taaaaataaa gctcaggaag
    34921 taaaagataa cggaacagcg acccaagaac aaataaacga agcagagaaa agtttgaaaa
    34981 cagcccttgc tgacttatct gttgacaaaa cagctttggg aagcgctatc gatacagcta
    35041 ctaagaaaaa taaagagaat tatacaaatc aaacatgggc agagttggaa acagcgctta
    35101 cagcagcaaa atctgtaaat actaacgagt ctaaacaaag cgacgttaac gaagctgctg
    35161 aaaaattaac tgcaactatg gaaaaattgg ttgaattgtc tgaaaagcca cgtttgactc
    35221 tatctattga aaagagagac atagatcgaa aagctacggt cacgtatact ttggaaaatc
    35281 cagcaaatac tcaaataaaa tcaataactg caactctgaa aaaaggagag gaagttgtta
    35341 aggattttgt tttaacagaa gaaaatctta aaactaatca tttaactgct ttgtttgaaa
    35401 agctagacta ctacaaagaa tacactctat ctacggatat ggtatataac agaggaaatg
    35461 atgatgagac ggagagtatt tcagaagaac taattcagct gaatcttaag aaactagaat
    35521 tgaaagatat ccagacagtc tctctgatga aatttgaaaa tggtcaagaa agtcaggtta
    35581 cacacttgtc tgataaaccg accgatttga gtaaattata cttaaaagtt acatcatcaa
    35641 cgtctaagga tgctgtgtta gccgttagct ctatagaaga agagattatt gaaaataaaa
    35701 aaatctttaa aattcatgca gatacaccag aattagtagt tcgtaagaaa gatggcagtc
    35761 tttctaaggg atttgactat tacatggaga gagttatccc tcatgatggt gatatttatt
    35821 atgattttaa agacttgatt tcagctatga catctaatcc tacaggtacg tttattttag
    35881 ggagagatat ttcctcgcgt aatgtaaaac cggatggaaa tggaaaatct tatatcaaag
    35941 gtgaatttaa aggaaaacta cttggtacaa atgataatgt tagacactcg atctttgact
    36001 tagaatatcc attgtttgat actataaaat caggagtcgt gaaagatatt gatttcaagc
    36061 atgtcaatat ggtattccca gatagcaatc aaggagataa cgtagcaaca attgcaagag
    36121 taatcaaaga taagacaaaa attgagaatg ttaatgttga aggttatctc gagggtcgag
    36181 atcatgtagc tggtttagtt aataatcttg aaggtaattc cgaaattgaa aatgtatcct
    36241 ttacaggaaa gattaagtct aaaggtggta attctattac agcaggtatt gcaggtagaa
    36301 atatcttatc tcgtgttaaa cgtgcctatg taaatgcaga tatagaggta catcgatcat
    36361 ctaattctag catgcttgtt gcagtaaatg gaataaacgc agatgcaagt ggtggttggg
    36421 gaacctgggg tagacttact gagtcagttg ctaaaggaac attagaaacc aagcaaggag
    36481 ggcaagctgg aggagcctct tctacagtct ggccttatgg agcaattgat aatgttgtca
    36541 gctatgcaaa agtgaccaaa gggaaagaat tatttggatc agatggtgat ttaaattatg
    36601 attggtttat gaaaaaaatt agtaatattt ttggtgttca aggcatcagc tcaggcgatt
    36661 cgggtagtga ttctaaattt acgcgtattt ctgaggaaga agcaaatcaa aaagttgctt
    36721 cttataatat tacagctccc aacttgatga gtgactcaag tcttttggta gacagactca
    36781 atgaaagttg gaaaaatact gatcaatttg aaagtataca ggattatcaa gcccaaaacc
    36841 aattaattta ccagaacttg actaaattta ctccttatta caataaagaa tttattgttc
    36901 atgaaggaaa tgctctcact cctgaacagg aaatattgaa gactaagaaa atcaaatcga
    36961 ttgtagggtt gaaaggaaca gagttcgttg tagatggcag tgatattgat actatcatgc
    37021 ttcattttga ggatggtagt cagaagcgat ataaggtaac ctctactggt aagttttcga
    37081 taactaattt accggaatat caggttgaag atttaaatgt ggtgtataca tcagaacata
    37141 tagtacatcc actagattcg tcactgataa ataaccttgt tgaagaattg aaaaaagtag
    37201 aattgtatac agagtctact taccaagttc taggtattga taaagataat gctaacaaat
    37261 tgaatagaac taagagatta ttcttagatg agtcattaga tgctgttaaa acacaattgc
    37321 ctacctttgt aaaaacaatg tttgaaaatg agtggttgca catcaatgga gaatctagtg
    37381 gagctgtcgc tgctttacga caaaaaatca tggataataa gacggctata ttgcttgctt
    37441 tgacttatat caatcgttat tatgatgtta aattctcaga ctataatatt aaaaaactga
    37501 tgctctttaa accaactttc catggtgaaa agattgatct attagatcga ttaatccgac
    37561 taggatcatc tggagaaaat agattaaaag gttcagaaaa tgcagaaacg ttcaagcagt
    37621 tatttgctag cgaaacgaag cagaaggatt tggtgactta tttagactac aatcgctctt
    37681 tgttgactaa ttatcaaaca acaggggaat ggtttaaaga aacgactaag gattatattc
    37741 aatttgagga acgtccatcc ttagtagagg agattaaaga tgccaaatat cgagtttacg
    37801 ataatttaac cgcaccgtat tatcaaggat atatcctacc tctcttaacg ttgaagaata
    37861 ctcatttagc aattttatcg aactatagta ctatgacatt tgtcagccgt gaaaaacgcc
    37921 ctaattggaa aaatgaagat tttgataagt gggtgaaata tgtagcaact gctcatagaa
    37981 accatgttga tacttggtat aagattttac ctgataatat caaaggtaaa atggttaaag
    38041 agaatgttac tgctgtttgg gaaggattga gcatcccagg aagtgaatgg gtagaccaga
    38101 atgctgtaga tagaaaagga agagattacg ccccagctcg agaattcttt aatcttgtag
    38161 gtggtcctat gggaggttgg tatgcttacc atggttatgg tgcgcatgct ggaggaagaa
    38221 atcgggttaa ttatgaggtg tttgatgtat taagtgagta tggtatatcg gtctttactc
    38281 atgaattgac tcacgttaat gatacttgga tttacttagg agggtatggt agacgtgaaa
    38341 atatgggacc tgaagcttat gctcagggat tattccagtc tcctgttcca ggtcagccgg
    38401 gttggggggc gcttggtctc aatatggcat ttgaaagaaa aaatgatggt gatctaattt
    38461 ataatgcctc cccaactcaa tttgaaaata ggaaagagtt agatagttat atgaaaaatt
    38521 ataacgatac tctcatgatg gtggactact tggaaggaga tgcagttatc tctaaaggta
    38581 aagaagctat tactaaatgg tttaaaaaag ttgaacctaa ggttgttagt caaacagctc
    38641 agtatgatac ggttcgtcag ttgactgctg aagagaaaga aaaactttct gtttctagtg
    38701 ttgatgattt agttgatcaa ggattaatgt cagacagagc tgtaggaaat aatacctata
    38761 atccagctga ttttgaaaca agttatattg cgatagatta tatgactggt atttatggtg
    38821 gaggaaagaa tagtgtaggt tcaccaggtg ccttgatgtt taaacataat actttccgta
    38881 tgtggggcta ctatggtttt gaagaaggtg ttctaggata tgcttctaat aaatttaagc
    38941 aagcatctag agatgaaggt catgctggac ttagtgataa ctttattatt tctaagattt
    39001 ccaaagggga atttttaact atggaagcat ttaaaaaggg atattttaag aaagtagtag
    39061 aagagttaaa aactaaaggt attcgtcctg ttactatcaa tcaaaaaaca tatagcacct
    39121 ttgaagaatt gcaagaagga tttaagcagg ctgttgaaag agatttgaag aaaaatcagt
    39181 tagatgagag ggaaacaaga aacttcaaat tccaagtttt cagacaactt cttcaacaaa
    39241 cagatagctt taaaacttct atctttagat aatcgaaatc tctcatctgc tttgcggatg
    39301 agggttttct tattttatgc tatacttaaa gtatgcatag aaaaacagtg attgatttta
    39361 ggactttggg ggagagatat acctttaccc agcctattaa agagttgaaa acgagaaatg
    39421 tagaagaagt ggcagatttg ctggcacaag tggaaagcta ccaagagcaa ggttattatg
    39481 tggtggggta tgtcagctac gaggctgcac ctgcttttga ggaaaaatta gcagttcaca
    39541 aggatcccct actgggagag tacctgcttt attttactgt tcatgatagc gtagaaactt
    39601 cccctattcc tctgacttat gaggatattg atttgccctc aaattggcag gaagtaacgt
    39661 ctgcagcaga ctatgaaaag gccattgccc aaattcacca tcatttacgg cagggagata
    39721 cctatcaggt caactacacc gtccaactta agcaaaagtt aaatgccaat ccttttgcca
    39781 tctacaatcg tatggtggta gagcaggagg cgggctacaa tgcctatgtg gaacatgacg
    39841 agatggcagt gatttccatg agcccagagc tcttttttga gcaaaatgat cgcgagttga
    39901 caacacgacc aatgaagggg acgactcagc gtggggtaac tgaccaagaa gatcttgaac
    39961 aggccagttg gttggaacag gatcccaaaa atcgctctga aaatatgatg attgtggacc
    40021 tcttgcgcaa tgatatgaac cgtatttctg aagttgggag cgagcacgtg gagcgtctgt
    40081 gtcaggtaga gcagtattca actgtttggc agatgacttc gaccatcaag agtcagttgc
    40141 gagaggatgt ggaccttgtt gaaatcttcc actcactctt tccttgtggt tccataacgg
    40201 gtgcaccgaa aattgcgaca atggagatta tcaaggactt ggagcctcaa ccgcgtggag
    40261 tctactgtgg aacgattggt ctcttgcttc caaatggacg acggattttt aatgtggcca
    40321 ttcgtaccat tcaacttcac aaaggtcaag ccatttatgg agttggcgga gggattactt
    40381 gggatagcac ttgggaatct gaataccgtg aagttcatca aaaggcagca gttctctatc
    40441 gtaaacaagc tcgcttccaa ttaattacaa ctggaaaaat cagccaaaaa caactgatgt
    40501 ttgaagaaca acatctggaa aggctgagaa aagctagtcg gtattttgct tatccttttg
    40561 acccagaaat tttgagacaa aagattgaag cagagtgtca gacttgtgat gctaatcaag
    40621 attaccgctt gcgaatttct ctcagcaagt ctggagagat agaattcagt cgtcaaatct
    40681 taacacctct tagtccaagt ttttgtcagg ccaaactttg tctgcaagaa gcgaatttga
    40741 atcaatcctt tacctatttt aaaacgactt acagaccgca tttgagcata gaggaacaag
    40801 agaagattta ccataatgga aaaggagaac ttcttgaaac ctctatcgga aatttggttc
    40861 tgaaaatcga tgggaaactc tacacaccgc ctatccgact tggaatcttg ccaggaattt
    40921 atcaccagta tttactagaa acaggacagg tagaagagaa agtcttgacc ttggcagatt
    40981 ttgcccaagc agaagctatt tacggctgta atgcagtgag aggcttgtat gagttgcaag
    41041 tgataggatt gtgagtttta gctattaata gtttttaata tatattaaaa tatattggtg
    41101 tttacttttg atgagatatc atatttgtgt tataatgtaa ccgtaaacaa tagaaattta
    41161 aaggagattt ttgatgaaat caaaaatagt tttgggagct tcgctagcga tcgcaacact
    41221 tagcttagta tctcttgtcg agattgaagg actctcaccg tttttaatag agaatgttag
    41281 cgcaaatact cattctgcaa ataaagttat taatcataaa gtaagtattt acttagaaaa
    41341 tgctgatgaa ggtaaaggtc taactgtaaa cttttcaaca gacagtgtta gtccaaattt
    41401 atttgatgag ttcgaaaaaa agagtggaat tacaataact actatgttag tgaatgctaa
    41461 gacaggtgaa gttgtagaaa aaagattaac accaagcgtt tttttacgtt ccaatgattt
    41521 aaccagtggg accatatctt cgtttatttt tagtgaatat cctgatggag aatataaata
    41581 tgttgtgtct aaaggagact ttatcgatcc taagactcag tttaaacatc agtatagagg
    41641 agaatctcca gtttttagaa tacgtaatcg aaaatatgtg gagttgggaa caactgataa
    41701 aaaattagat gaaagacgtg ataatagcgt ttataaagat ggggttgttg aacacaaggt
    41761 aaatttaagt ttaacaagtt atcaaggagg taatggagtt actgcaattt tttcaactga
    41821 tagtgttaac tctaacttac ttaattcttt tggtgaaaag gctaaaaaag ttttgattag
    41881 gtctaagtta attaatgtta agactggcga ggttattgat gaaacgtttt ctccaaaagt
    41941 aagtttaacc tctaaaattt tgaaaagtgg ttctacagca gtattttatt ttatagattt
    42001 aactgatggc gaatataaat atgttgcgta tgaaagccag caatatactg atcctcaaac
    42061 aacattgact catcagtata gaggagaatc tcctattttt agtatcaaag atggaaaatt
    42121 ttctggttta gtatctgcct caaaaccaga cgaaaacccg aagccaacgc caaaaccgga
    42181 tgagaaacca aaaccttcag caccacaaca ggagaaaaca aaacctacag ttcagtctgg
    42241 ttgggtaggt tcatcttatt atcaaaatgg taaaaaagtc actagtaagt ggatttttga
    42301 taaaaaatat aattcatact tctatctaga tgcatcagga aattatgttc aaaacgcttg
    42361 ggtaggtaac tattatctca aatcaggcgg atacatggct aaaagtgagt ggatttatga
    42421 taagaactat ggttcatact actatctaac atcagaaggc agctacgctc gtaacacttg
    42481 gtcaggcaat tattatttga agtcaaatgg taagatggct aaaagtgagt gggtatacga
    42541 tagtaactac aaatcatatt actacttgac atcagaagga agttatgctc gtaacacttg
    42601 ggtaggcaat tactatctta aatcaaacgg taaaatggct gttaatgaac gtacaccaga
    42661 tggttatcgt gtagatggtt caggtaaatg ggttaaataa gaaactaaaa aataggataa
    42721 taggtaatat cagatgaata aaaaaaatta ttttcatgtg ctttagcatt ttcaacgatt
    42781 ggaacattgt caacgattga taaatcagga gttcttcctt tttcagcgca aacggtgcag
    42841 gctgacatac aaacgcttac cccaatggca aaatattata ttattcttcc gaaggatgca
    42901 gaaatatata aaacttggag aggtactgtc aatattccca ttattgatgc tacaaaaact
    42961 actccagaat tatcttattt caaagaagat catcgcaact atatagctaa tgagaataag
    43021 tctggtgcca attacataga gtggaaggga acagtagaag agtttaaaga ggccattaag
    43081 aagttgactg ataaaaaatc aactactgca acaccaaaaa aggatgaaaa gccaacacca
    43141 aaaccggatg agaagccaaa accaacacct acagttcagt ctggttgggt aggttcatcc
    43201 tattatcaag atggtaaaaa agtcattagt aagtggattt ttgataaaaa atataattca
    43261 tacttctatc tagatgcatc aggaaattat gttcaaaacg cttgggtagg taactattat
    43321 cttaaatcag gcggatacat ggctaaaggt gaatgggttt atgatgccac ctatcaagct
    43381 tggtattatt tgacatcaga tggttcttat gcttacagta catggcaagg aaattactat
    43441 ctaaaatcgg atggtaaaat ggctgtcaat gaatgggttg atggtggacg ttattatgtt
    43501 ggcgctgacg gagtttggaa ggaaggtcaa gcaagtacag cttcttctag taatgatagc
    43561 aatagtgaat attctgctgc tttaggaaag gcaaaaagtt ataattcgtt attccacatg
    43621 tcaaaaaaaa acgtatgtat agacaattaa cttctgattt tgataaattt tcaaatgatg
    43681 cagctcaata tgccattgat cattagatga ttaacagata ctggtaggcg aaaaaattcc
    43741 ttataattca cttacgcaaa cctttgcata agtgaatgga ttttgatata ctagtactgt
    43801 aagcattttc aattactaca caatgaaaaa ggagaatatg atgagtcaaa agattattgg
    43861 gattgacctt ggtggaactt ctatcaaatt tgcaatctta acaacagcag gagaaatcca
    43921 aggaaaatgg tcaatcaaga ccaacatttt ggatgaggga agtcatatcg ttgatgatat
    43981 gattgagtct attcaacatc gtttggactt gcttggattg gcagcagcgg acttccaagg
    44041 cattggaatg ggatcaccag gtgtggttga ccgtgaaaaa gggactgtta tcggtgccta
    44101 caacttgaac tggaaaaccc ttcaaccaat caaacaaaag attgaaaaag ccttgggcat
    44161 tccatttttc atcgataatg atgccaacgt agcagctctt ggtgagcgct ggatgggtgc
    44221 tggagataac caaccagacg ttgtctttat gacactcggt actggtgttg gtggcggtat
    44281 cgtcgcagaa ggcaaattgc ttcacggtgt tgctggtgca gcaggtgagt tgggccacat
    44341 cactgttgac tttgaccagc caattgcatg tacttgcggt aagaaaggct gccttgagac
    44401 agttgcttca gcaacaggga ttgtcaactt gactcgtcgc tatgccgatg aatacgaagg
    44461 cgatgcagcc ttgaaacgct tgattgataa cggagaagaa gtaactgcta agactgtctt
    44521 tgagctcgca aaagaagaag acgaccttgc tttgattgtt taccgtaact tctcacgtta
    44581 cttgggtatt gcatgtgcta acattggttc aatcctaaac ccatcaacaa tcgtcatcgg
    44641 tggtggtgtg tcagctgcag gagaattcct tctacaaggt gttcaaaaag tctacgatga
    44701 aaatagtttc ccacaagtac gcacatctac taaattagca cttgcaactc taggaaatga
    44761 cgctggagtt atcggagcag catcacttgt attgcaataa gataatgaga gaggaaaatg
    44821 ctaacctaga gttagtaatg ttcctctttt attttttatg ctatactagt taggacaatg
    44881 aatgaggtga aacgaaatga caaaagcaga tacgattttt aaagagaata ttgaacgcat
    44941 tctaaaggaa ggtgttttct cagagcaggc tcgtcctaag tacaaggatg ggactgttgc
    45001 taattccaag tatgtaactg gtgccttttc cgagtacgac ttatctaaag gagaatttcc
    45061 tatcacaacc ttgcgtccca ttgcaatcaa atccgccatc aaagaagttc tctggattta
    45121 ccaagaccag tcaaatagct tagaagtgct taatgacaag tacaatgttc actactggaa
    45181 tgactgggaa gttggagaca cgggaaccat tggtgagcgc tatggtgccg ttgttaagaa
    45241 acacgacatt atcaataagc ttctcaaaca gttggaaacc aatccttgga accgccgcaa
    45301 tattatttcg ctctgggatt accaagcttt cgaagaaaca gatgggctgc tcccgtgcgc
    45361 ctttcagacc atgtttgatg tccggcgtgt tgatggggaa atctatctgg atgcgacctt
    45421 gacccagcgc tccaatgata tgctggtggc ccaccacatc aacgctatgc agtatgtggc
    45481 tttgcagatg atgattgcca aacattttgg ctggaaggtt gggaagttct tctacttcat
    45541 caacaacctc catatctatg ataatcaatt tgaacaagct caggaattgc tccgtcggga
    45601 gccgtcaaac tgccaaccac gcttggtttt aaatgttcct gatgggacta atttctttga
    45661 tatcaaagca gaagattttg agttggtgga ttatgaccct gttaagccac agttgaagtt
    45721 tgacctagct atttaaaaga atagaaaaaa gaagttgaga ataatcccaa cttcttttgt
    45781 ttcttaacgt gatacgcggc gacgagctgc ttttttacgg ttttcttcga tgaaagctgc
    45841 tttttgctct tctggttcga ttactttctt tttaaatgcg tatactgcac ctgcaacggc
    45901 agcgacagtt cctgcgacac ctgttacaag acctttagcg aatcctttag ccatgagtct
    45961 tcctccttta tattctcaat cagccagcct cctcaagagg tcacattttt ctgactgacc
    46021 tttttgtgtt ataataatag taacgaaaaa atgggaattt ttcaaggaaa aaagatgaaa
    46081 acaaaaataa ttgtgattgt tggaccgact gctgttggaa agacggctct agctattgaa
    46141 gttgcaaagc gctttaatgg cgaagtggtt agtggagata gccagcaagt ctatcgagga
    46201 cttgatattg ggacggccaa ggctagtcca gaagagcagg cagctgttcc tcatcattta
    46261 atcgatgtta gagagataac cgagtcttac tcggcttttg attttgtttc agaagctaag
    46321 atgactattg aggatattca gagccgtggc aagctagcca ttatcgccgg tgggactgga
    46381 ctttatatcc agagcttgct agaaggttac cacctaggtg gggagactcc tcatgaggag
    46441 attttagctt atcgagctag tttggagcca tattcagatg aggaattagc ccatttggtg
    46501 gagcaagcag gccttgagat tccccagttt aatcgtcgtc gtgctatgcg tgccttagaa
    46561 attgcccatt ttggtcagga tttggaaaat caagagatct tgtatgaacc gctgattatc
    46621 tgcttggatg atgaacgtag tcaactttat gagcgtatca accaccgagt ggatttgatg
    46681 tttgaggctg ggcttttgga tgaggccaag tggctgtttg accattcccc taatgtacag
    46741 gctgctaaag gaattggcta taaggaactc tttccttatt tccgtggaga gcagaccttt
    46801 gaggaagctc gtgagagtct taaacaggcg acccgtcgtt ttgccaagcg tcagctgacc
    46861 tggttccgta atcgcatgca ggtcaccttt tatcagattg gagaatctgg tgtacaagac
    46921 cgcattttaa gccagataga ggagttttta gatgattgaa acggagaaaa aagaggagcg
    46981 agtcctgctg attggtgtgg aattgcaggg tatggacagt tttgacctct ccatggaaga
    47041 attggctagt ttagcgaaaa cggcaggggc agtcgttgta gatagctaca gacaaaaacg
    47101 tgaaaaatat gattccaaga ccttcgtcgg ctctggtaag ttggaagaga ttgcgcttat
    47161 ggtggatgca gaagaaatca ctactgtcat cgtcaacaat cgtctgaccc caaggcagaa
    47221 tgtcaatcta gaggaagttc tcggtgttaa ggtcattgac cgtatgcagt tgattttgga
    47281 tatctttgcc atgcgggctc gaagccatga agggaagctc caagtccacc tagcccaact
    47341 caaatacctc ttgcctcgct tggttggtca ggggattatg ctcagccgtc aggcaggggg
    47401 aattggttcc cgtggtcctg gtgaaagcca actggagctg aaccgtcgta gcgttcgcaa
    47461 tcaaatcacg gatatcgagc gccagcttaa ggtggttgag aaaaatcgtg cgactgtcag
    47521 agaaaaacgt ttggagtcta gcacttttaa gattggtttg attggttata ctaatgctgg
    47581 gaaatcaact atcatgaaca tcttgaccag taagacccag tatgaagcag atgagctctt
    47641 tgcgactctg gatgcgacaa ccaagagtat tcatctggga ggcaatctcc aagtaacttt
    47701 gacagatacc gttggcttta tccaagattt gccgacagag ttggtgtcca gtttcaagtc
    47761 aaccttggaa gaaagcaagc atgtggacct tctggttcat gttatcgatg ctagcaatcc
    47821 ttaccacgag gagcatgaaa aaacggttct ctccatcatg aaagacctgg acatggaaga
    47881 tattcctcac ttgacgcttt ataataaagc ggatttggtg gaggatttca cgcctaccca
    47941 aacgccatat accctcattt ctgccaagtc tgaggacagt cgtgaaaact tgcaagcatt
    48001 attgctagat aagattaagg aaatttttga agcatttacc ctgcgagtgc ctttttcaaa
    48061 gtcctacaag attcatgatt tagagagtgt tgcaattctg gaagaacgtg attatcagga
    48121 agacggcgaa gtgattacag gctacatttc cgagaaaaat aaatggaggt tagaagaatt
    48181 ttatgactga tattaaaact ttggctctaa agtatggagg ttatacaagt ctggacaagg
    48241 tctatctgga tcagcttcta gctggtaaaa cagatcagga gcagttaaca cttattacac
    48301 ctccgccaag tgttgttaat gcctactttg cagaactcta tcagaaaaag agtcctcagg
    48361 ctgcgacgga ttattttgca gaactcagtc aggaactgaa tctttacaat actgagccaa
    48421 gtttcaccct agaaaataag ccttttattc ggcttaatct gtctggtaaa tcctttggtt
    48481 tttgttatga gagtgacggc cttggtcgga ttttctttga aaatgaggag aaaatctcgg
    48541 atgacttgct ctttgaaatt gcgcaaattt tcccccatca attagtcttt gaagagtctg
    48601 gtaagattta catgaagcct gtcgaggacg aggaagttat cagcctagaa agtctcacag
    48661 ctttgactga tttggaaaga ttggctgatg gtcgaaaacg tctcaaaggc tacagccaag
    48721 aggatttatt gcaagaagct gctgcttttt ctggcaaacg ctatttccga tcggaaaacc
    48781 gcacagccat gttatatatt gattaattag aaagtatcga atggatattc aatttttagg
    48841 aacgggggct ggtcagccct ctaaagcccg caacgtttca agtctcgccc tgaaactttt
    48901 ggatgagatt aacgaagttt ggctctttga ctgtggagaa ggtacgcaaa atcgcattct
    48961 ggaaaccaca attcgaccac gtaaggtcag caaaatcttt attacccatc tgcatggaga
    49021 ccacattttt ggtttgccag gtttcctttc tagccgtgcc tttcaggcca atgaagagca
    49081 gacagatttg gaaatctacg gacctcaagg aatcaagtca tttgtcttaa ccagccttcg
    49141 tgtgtcaggt tctcgtctgc cctaccgcat tcatttccat gagtttgacc aagattctct
    49201 gggtaaaatt cttgaaaccg ataaattcac tgtgtatgca gaggagctgg accacactat
    49261 tttctgtgtt ggctatcgtg tcatgcaaaa ggatctagaa gggacgctgg atgctgaaaa
    49321 actcaaggct gctggtgttc cgttcggccc gctttttggt aaaatcaaaa acggccagga
    49381 tcttgttttg gaagacggaa ctgaaatcaa ggcagcagac tatatctcag cgccacgtcc
    49441 aggtaagatt atcactattt taggagacac tcgaaaaacg ggtgccagtg tgcgtctggc
    49501 tgtcaatgca gatgtcctag ttcatgagtc cacttatggc aagggtgatg aaaaaattgc
    49561 tcgtaaccat ggtcactcaa ctaatatgca agctgcacaa gtagcggtag aagcaggtgc
    49621 caaacgcctc ctactcaacc atatcagtgc ccgtttcctc tcaaaagata ttagcaaact
    49681 caagaaagac gctgccacaa tttttgaaaa tgtccatgtg gtcaaagact tggaagaagt
    49741 ggaaatctag cagtcacaga aaggataagt atgcctacta ttctcattac cggagctagc
    49801 ggtggtctag ctcaagaaat ggtcaaactc ctgcccaatg accaactcat cttgcttggt
    49861 agaaataagg aaaaattagc ccaactctac ggaaattatt cccatgcaga attgattgaa
    49921 attgatatta ccgacgattc agccctagaa gctctggtaa ctgatcttta tctccgctat
    49981 ggcaagattg atgtcttgat taacaacgct ggttacggga tttttgaggg atttgaccag
    50041 attgctgata aagatattca ccagatgttt gaggtcaata cctttgccct gatgaatctg
    50101 tctcgtcacc ttgcggctcg tatgaaggaa agcagcaaag ggcatatcat caacatcgtc
    50161 agcatggcag gtctaatagc tactggcaag tctagtcttt actcagcgac caagtttgcg
    50221 gctattggtt tttcaaatgc tctgcgactc gaacttatgc cctatggagt ctatgtgaca
    50281 acagtcaatc caggtccaat ccgaacagga tttttcgacc aagccgaccc agatggaact
    50341 tatcttaaat cggttgaccg cttcctgcta gaaccagatg cagtggctaa aaagattgtc
    50401 aagattatag gaaaaaacaa acgagaactc aatctcccga ttttgttgaa cctagctcat
    50461 aagttttata ccctctttcc taagctagct gataagttgg caggggaaac ttttaattat
    50521 aagtaaaaag aaccaatgtg caggttgttg ctagcctaca tattggttct tatcatttct
    50581 caactatcaa actgaacttc ttctaggaga tagtctataa agcgttcgcc catcttagat
    50641 aggctggttt tctcatgctg gatatagacc agctcgatcg ggtcatcaat atccagtggg
    50701 atagaaacga tattgtctcc gtttaggttg ctgttcaaaa tccctgtcgc aatggtataa
    50761 ccatccaaac caatcaagag attaaagagg gtggcacggt cactgaccac aatggatttc
    50821 ttgtggtgtt cttgagaaag aatctcttct gaaaagtaga aggagttgtg cgtcccttgg
    50881 tcatagctga ggtaagggaa attctccaaa tcagacagtt tcaccttgtc tttctttgcc
    50941 agagggttgg tcttgctgac aaagatatgt ggttgcgctg tgaagagatg gtgggctagc
    51001 aggtgattgt catccagcat cttggttaaa acatcacggt tgtaactgtt taagaagagg
    51061 accccgacct cactgcggaa gttcttgacg tcgtcgataa tctcccaagt ccgagtttca
    51121 cgaaggaaga gttcgtattt ctccatatcg cttttcttga gcaaagagac aaaggcattg
    51181 accacaaagg catagtgttg agacgaaacg ctaaatagtt cgcggtgggc gacaggattt
    51241 ttatagcgtt cctccagaag ctgggtctgc tcgacaacct gacgggcata agagagaaac
    51301 tccatcccat cacgggtcaa ggtgattccc ttgggattgc ggataaagat ctcaatgccc
    51361 atttcatttt ccaaatctcg cactgcattg gagagacttg gctgagtgat aaagagttgc
    51421 ttggctgcct cattcatgga gccagtttcg acgattttga taatataatg taattgttga
    51481 attctcatgt ttttattgta ccatacttgc cttagaatcg ctaaagaaga taggaaaata
    51541 aggagcattg tgtgagtctc ttcttgaaaa aaacacaaaa ttttgctaga atgagtctta
    51601 tgaaaacatt ctatgatgtg cagcaattcc tcaaacgatt tggtattatt gtttacatgg
    51661 gaaaacgctt atatgatatt gaactgatga agttggaact atctcggatt tacgatgcag
    51721 ggttgatgga taaattagac tatctagagg cagaagcagt tcttcgcaga gagcacaagg
    51781 tagaattgga ttatattgag aaaaatggag aaaagaacta atggttactt ggattttgtg
    51841 ggcacttata ctagcaatgt tggcgtggat gggctttaac tatcttcgta ttcgccgtgc
    51901 ggctaaaatt gtggacaatg aggagtttga agccttgatt cgtacgggtc aattgattga
    51961 tttgcgcgac ccagcagaat tccacagaaa acatatcctt ggtgcacgca atattccttc
    52021 aagtcagttg aaaactagtc ttgcagccct tcgtaaagat aaacctgtcc ttctctacga
    52081 gaaccaacgt gcgcaacgag ttacaaatgc agctctttac ttgaaaaaac aaggtttttc
    52141 tgagatttat atcctttctt atggcttgga ttcttggaaa gggaaagtga agactagcta
    52201 accttatttc caaattagtc gaatgatagg atgaagctat tgttttatag tataattaat
    52261 ttgtataaaa tttaaggagt tcttagaaca taaaagaaaa gaagaaaaat ccactttttg
    52321 tgggtatctt gtcgattatt cttggtttgt tatttccaat tgtaggcctg attttgggta
    52381 tcataggatt ggtcttggct atttcatacc aaaaagagtc ataattagac tataaaatag
    52441 aaaagattct taatatctta ggaattgtga tttctgtagt taactggatt gtagcaatcg
    52501 ccttaatttt tcggtaaata aaagaaaaaa gctttagttt taaagctttt tttgttttat
    52561 cgactcatct ctaaatagtt tttaatgatt tgtaactctt tttggttcaa agggcggtag
    52621 ttactttctg ctaaatctgg gttcaatgtg aagtccccaa attggattct cttgaggata
    52681 gtcaccttaa caccaaccga gaggaacatt ttcttgattt gatgaaattt tccttctgaa
    52741 atggtgatag aggcttgact gatggaggga cttgcagata gaatctctag ttttgcgggt
    52801 ttacagacag taccatctaa aaagacaatt cccttttgaa aggcttggat atggtcaggt
    52861 gttagaagtc cattaacctc aacttgataa gtcttatcga catgatattg gggatggagg
    52921 agttggaagc ccaagggacc gttatcggtc aagaggagga gtcccgttgt atctcggtcc
    52981 agtcggccaa cggcatagag cttgtcagac tggatgtcag atggaagcag gtccatgacg
    53041 gtcggaagtt ccttgtcttt gttggctgta acgacaccag caggtttatg aagcataaga
    53101 taggtgtgtt catagccttg aatgattcga tcctgaaaaa ggagttcttg tagtcctgta
    53161 tcgatatttt gagctaggga gcgggctggg caaccatcga ctagaatttt ccctctgagg
    53221 agtgcttgct tcatggcctt tcggctaact ttttcttggg ctaataaatt atctaaacgc
    53281 atactgtgcc tatcttatca taagtcgctt gctttgaaaa ggcttgacgt gaaaagaaaa
    53341 gcggagtgaa aacatttaca cttgcttgag ttatgttatt tatttgaaat tatggtataa
    53401 tcgttcagtt agaaaataaa ttttgaatat tatagaggaa atcatgacaa aattaagaga
    53461 agatatccgt aacattgcga ttatcgccca cgttgaccac ggtaaaacaa ccctggttga
    53521 cgaattattg aaacaatcag aaacgcttga tgcacgtact gaattggcag agcgtgctat
    53581 ggactcaaac gatatcgaaa aagagcgtgg aatcaccatc cttgctaaaa atactgccgt
    53641 tgcttacaac ggaactcgta tcaacattat ggacacacca ggacacgcgg acttcggtgg
    53701 agaagttgag cgtatcatga aaatggttga cggtgttgtc ttggtcgtag atgcctatga
    53761 aggaaccatg ccacaaactc gtttcgtatt gaaaaaagcc ttggaacaag accttgtccc
    53821 aatcgtggtt gttaacaaaa tcgataagcc atcagctcgt ccagcagaag tagtggatga
    53881 agtcttggaa cttttcatcg agcttggtgc agatgacgac cagcttgatt tcccagtggt
    53941 ttatgcttca gcgatcaacg gaacttcttc attgtcagat gatccagctg accaagaagc
    54001 gactatggca ccaatctttg acacgattat cgaccatatc ccagctccag tagataactc
    54061 agatgagcct ttgcagttcc aagtgtcact tttggactac aatgacttcg ttggacgtat
    54121 cggtatcggt cgtgtcttcc gtggtacagt taaggttggg gaccaagtta ccctttctaa
    54181 acttgacggt acaactaaaa acttccgtgt tacaaaactc ttcggtttct ttggtttgga
    54241 acgtcgtgaa atccaagaag ccaaagcggg tgacttgatt gccgtttcag gtatggaaga
    54301 catctttgtc ggtgaaacca tcactccgac agatgcagta gaagctcttc caatcctaca
    54361 catcgatgag ccaactcttc aaatgacttt cttggtcaac aactcaccat ttgctggtaa
    54421 agaaggtaaa tgggtaactt ctcgtaaggt ggaagaacgc ttgcaggcag aattgcaaac
    54481 agacgtttcc cttcgtgttg acccaactga ttcaccagat aaatggactg tttcaggacg
    54541 tggagaattg cacttgtcaa tccttatcga aacaatgcgt cgtgagggct atgaacttca
    54601 agtatctcgt ccagaagtta tcgtaaaaga aatcgacggt gttaaatgtg aaccatttga
    54661 acgtgtacaa atcgacactc cagaagaata ccaagggtct gttatccaaa gcctttctga
    54721 acgtaaaggt gaaatgttgg atatgatttc aactggtaat ggtcaaactc gtttggtctt
    54781 ccttgttcca gcgcgtggtt tgattggata ctcaactgag ttcttgtcaa tgactcgtgg
    54841 ttacggtatc atgaaccata ccttcgacca atacttgcca ttgattccag gggaaattgg
    54901 tggacgtcac cgtggtgccc ttgtttctat cgatgctggt aaggctacaa cttactcaat
    54961 catgtctatc gaagaacgtg gtacgatctt tgtcaaccca ggtactgagg tttatgaagg
    55021 aatgatcatc ggtgaaaact ctcgtgaaaa tgacttgaca gttaacatca cgaaggcaaa
    55081 acaaatgacc aacgttcgtt cagctactaa ggaccaaaca gctgttatca agacgcctcg
    55141 tatcttgaca cttgaagagt ctcttgagtt cttgaacgac gatgagtaca tggaagtaac
    55201 gcctgagtct atccgtttgc gtaaacaaat ccttaacaaa gcagagcgtg agaaagctaa
    55261 caagaagaaa aaatcagctg aataagagct agaaagagag aaagatggtc tatttagtcc
    55321 taggaatttt actgctccta ctctatgtat ttgcgacacc agaaagcatt aaagggactg
    55381 tcaatatcgt cgctatggta tgtattttag tggcactctt gattttattg gttctatctt
    55441 ttctgaaaat ttttcaatta ccaacagaaa tattcctagc aatagccatg ttgatcctag
    55501 cttactttag tgtgagagac atcacactca tgccagtcaa aaaaagtaaa agaagataaa
    55561 aaagagagtt tcggctctct ttttgctagg aattttacaa tagtttgaat tgctttttag
    55621 ttaacaccat ctcttttact tgtatagtat gaatgggaaa aacttgaata aaattcgtta
    55681 atggcatcta ttttatattt ggttagtact ggttgcatat tattttgaaa taaaactact
    55741 atataatatt attcatagag ataatatagt aaaacatcta aaaaattcga ttttttcctt
    55801 gacaacaaat aataaaaatg ttattcttat cacataagaa agcgatttca acaaaagaga
    55861 gaggaggatt tattttgttg cattgttgct caaggtgtga tttttttgaa agaaaaaata
    55921 aaatgaaaac gaaaaaacat agattacttg ctctagctct tatttcaaat tttacattat
    55981 tgggagctgc atcagctgct gtacaatatc cagatggagg agtatggaca tatggagaag
    56041 gttcaggagg tggttaggct ttttcaaatt actatcatgg taaaaaatat cattattcat
    56101 ccatcgtgag cagatgggat ggtcattctg ataaaggaga agctcctgct ggaaaaacct
    56161 cctatgcatg gatttggact aaatggggag aacaagtagc attttactat gactatgact
    56221 aatatttagt tttcttagat aattcccctt gtaagaaatt acagggggaa ttttgtttac
    56281 aaggagtcta ctatgaagaa actattcata ttattatcaa ctttttttct cagcttcttc
    56341 cttgcttgga ttattgtctt acgtgcgcca caatatttat atgcaagcta tgattccgtt
    56401 tctttacttc gtgtcaaaaa agatactcag gaaccgacgc gtgaggtatt tgaacaggaa
    56461 ttggagaatt ttgcaaactc agaacagagt ttaatagcta gaagaattgt agagccgagt
    56521 aaggatggga cgactcactt tacttatgca acttatggtc agggaacttt accaaaagaa
    56581 ttccaagaag ctagccaaga aagtcgtgaa cgtagtgatc cgctaaatag ttatctcctt
    56641 ttgtcaggct ccttgacgaa agaaaagctt gccgataaat taggagattt gggttataaa
    56701 gcaagtgctg accgaaagat accgccctat tttcttgctt ttcgaatatt actaaatccc
    56761 cttattttaa ttagtttagc aatatttggc ttatctttct ttgctttagt gattatcact
    56821 cggattaagg aaatgagagc agcaggtata aaactctttt ctggtcagac tctcttatcc
    56881 atcatggggc attctttatc gactgatatc aaatggctcc ttctatcagc cctcctttcc
    56941 ttcctaggtg ggggagtcgt tctttttagt caaggtttgt tttatcctat cttgttagcc
    57001 acctatggtt ttgggattag tttctatctg ttgtttttat tggcgatttc aattttacta
    57061 atgcttcttt atctaatgag tttgaattac aaagcattag ttcccgttat taaggggaga
    57121 ttacccctta aacgcctgat gattttaacc ctattgtgtc agttagtagc tgtttttaca
    57181 gtaggctacg ctgttaagac aggtttgacg tcttaccaac gattgaaaga acttgaaatt
    57241 tcaaaacaag catggcagga tagagcagac tattatcaaa tttcttttgg cttaggtgat
    57301 agaggaaaag atacagaaaa tcagagcaag tggtatgcct ttgccaagga agcaatcgaa
    57361 gaagaacaag ctctttatgt aaaggataat ctgctccatt ttgccaatcc acaaggaaaa
    57421 aatgaacagg gagagacact ggatacctat agtccagatg ctaatacgct ctatgttagt
    57481 cccagttatt tggacaagga aaaggtcgtg gtagatgctg agaccaaaca gaagctagcc
    57541 catctccaaa aaggtgagtt tatcctcttg ctcccagaac atttgcgctc tcgagaagca
    57601 gaacttaaga aagtttttga agaaagattg agttattatg gaaaatctgg tgaggaggca
    57661 agtgctcctt tggattatga gatgaaagcg cacgttagtt atctttcaat gggagaaaag
    57721 cggtttgttt ataataacgg tgagaatccc gtatccactc agtatttgac tgatccgatt
    57781 ttagtggtat tcacgccgac ttctacaggt gatagtttta tatccttatc tagttggtct
    57841 atcaatgctg gaaaacaact ctttatcaaa ggatatgaga gtgggctaga actcttgaag
    57901 aaagctggaa tttatgagca agtatcctat cttaaagaag gaagaagtgt ttatctaact
    57961 cgttataatg aagttcaaac tgaaacagca actttaatct taggagctat tgtggggata
    58021 gctagttcct tgttactatt ttattctgtc aatcttctat atttcgagca attccgccga
    58081 gatattttga ttaaacgaat ttcaggttta cgattttttg aaacacatgc tcagtatatg
    58141 gttagccaat ttgccagttt tgtatttggt gctagtttct ttattttacg cagtagagac
    58201 tgggtaattg gcttactcac tttattagtc tttctagcta gtgcagtttt gacgctttac
    58261 cgtcaagcac agaaagaatc tcgtgtttct atgacaatta tgaaaggaaa ataggatgat
    58321 tgaactaaag aatatatcta aaaaatttgg aagccgtcag ctattttcag atacgaatct
    58381 tcattttgaa ggtgggaaaa tttatgcctt aatcggtaca agtggctgtg gtaagacaac
    58441 actcttgaat atgattggac gattagagcc atatgacaaa gggcaaatca tctatgatgg
    58501 tacttctctt aaggacatca agccttctgt tttctttaga gattacttag gatatttatt
    58561 tcaagatttt ggcttaattg aaagccaaac tgtcaaagag aatctcgatc tgggtttagt
    58621 tggtaaaaag ttgaaggaaa aagagaaaat ctctttgatg aaacaagctc taaatcgtgt
    58681 aaacctctct tatttggatt tgaagcaacc tatatttgag ttatcaggag gagaagcaca
    58741 acgtgttgca ctagcgaaga taattttaaa ggatccacct ttgatcctcg cagatgaacc
    58801 aaccgcttcc ttagacccta aaaactctga ggaattactt tccatcctag aatctttaaa
    58861 aaatccgaat cggaccatta ttattgcgac ccacaatcct ctgatttggg ggcaagtgga
    58921 tcaggtcatt cgagttaccg atttatcaca tagatgatat ggtaagattc agttagaaga
    58981 aagagtcaca aacacacttt gtggcttttt tatttccata aaaatggtaa aatagtagga
    59041 gtagaaatgg agttcgagac atgaaagtaa tagatcaatt taaaaataag aaagttcttg
    59101 ttttaggttt ggccaagtct ggtgaatctg cggctcgttt gttggacaag ttaggtgcca
    59161 ttgtgacagt aaatgatggg aaaccattcg aggacaatcc agctgcccaa tgtttgctgg
    59221 aagaagggat caaggtcatt acaggtggcc atcctttgga actcttggat gaagagtttg
    59281 ccctcatggt aaaaaatcca ggtatcccct acagcaatcc catgattgaa aaggctttgg
    59341 ccaagggaat tccagtcttg actgaggtgg aattggctta tttgatttca gaagcaccga
    59401 ttattggtat cacaggatcg aacggtaaga caaccacaac gactatgatt ggggaagttt
    59461 tgactgctgc tgggcaacat ggtcttttat cagggaatat cggctatcct gccagtcagg
    59521 ttgctcaaat agcatcagat aaggacacgc ttgttatgga actttcttct ttccaactca
    59581 tgggtgttca agaattccat ccagagattg cggttattac caacctcatg ccaactcata
    59641 tcgactacca tgggtcattt tcggaatatg tagcagccaa gtggaatatc cagaacaaga
    59701 tgacagcagc tgatttcctt gtcttgaact ttaatcaaga cttggcaaaa gacttgactt
    59761 ccaagacaga agccactgtt gtaccatttt caacacttga aaaggttgat ggagcttatc
    59821 tggaagatgg tcaactctac ttccgtggtg aagtagtcat ggcagcgaat gaaatcggtg
    59881 ttccaggtag ccacaatgtg gaaaatgccc ttgcgactat tgctgtagcc aagcttcgtg
    59941 gtgtggacaa tcaaaccatc aaggaaactc tttcagcctt cggtggtgtc aaacaccgtc
    60001 tccagtttgt ggatgacatc aagggtgtta aattctataa cgacagtaaa tcaactaata
    60061 tcttggctac tcaaaaagcc ttgtcaggat ttgacaacag caaggtcgtc ttgattgcag
    60121 gtggtttgga ccgtggcaat gagtttgacg aattggtgcc agacattact ggactcaaga
    60181 agatggtcat cctgggtcaa tctgcagaac gtgtcaaacg ggcagcagac aaggctggtg
    60241 tcgcttatgt ggaggcgaca gatattgcag atgcgacccg caaggcctat gaacttgcga
    60301 ctcaaggaga tgtggttctt cttagtcctg ccaatgccag ctgggatatg tatgctaact
    60361 ttgaagtacg tggcgacctc tttatcgaca cagtagcgga gttaaaagaa taatatgaaa
    60421 aaaattgtct ttacaggtgg ggggacggtt ggacacgtta ccctcaatct tttgttaatg
    60481 cctaagttca tcgaagatgg ttgggaagtc cactatatcg gggacaagcg tggtatcgaa
    60541 caccaagaaa tccttaagtc aggtttggat gtcaccttcc attctattgc gactggaaaa
    60601 ttgcgtcgct atttctcttg gcaaaatatg ctggatgtct tcaaagttgg ttggggaatt
    60661 gtccaatcgc tctttatcat gttgcgactg cgtccacagg ctcttttttc aaagggagga
    60721 tttgtctcag taccgcctgt tatcgctgcg tgtgtgtcag gagtgcctgt ctttattcac
    60781 gaatctgacc tgtctatggg cttggccaat aaaatcgcct ataaatttgc gactaagatg
    60841 tattcaacct ttgagcaagc ttcgagtttg tctaaggttg agcatgtggg agcagtgacc
    60901 aaggtttcgg atcaaaaaaa tccagaacca gatgaattgg tggatattca aagccacttt
    60961 aatcataaat tgccgactgt attgtttgtt ggcggttctg caggtgctcg tgtctttaac
    61021 caattggtga cagaccataa gaaagaacta acagagcgct acaatattat caatctaact
    61081 ggagattcta gcctgaatga gttgagccaa aatctttttc gtgttgacta tgtgaccgat
    61141 ctctatcaac ccttgatgga attggctgat attgttgtga cacgtggtgg tgccaatacg
    61201 atttttgagc tcttggcgat agcaaaattg catgtcattg tgccacttgg tcgtgaagct
    61261 agtcgtggtg accagattga aaatgcagct tactttgtta agaaaggcta tgcagaagac
    61321 cttcaagaaa gcgatttgac cttggatagt ttggaagaga agctttctca cttactaagt
    61381 cacaaggaag attaccaagc taagatgaaa gcttctaagg aattgaaatc tctagcagat
    61441 ttttatcaat tgttgaaaaa agatttatca taaggaaagt aaatgtcaaa agataagaaa
    61501 aatgaggaca aagaaatcct cgaagaattg aaagagttat cagaatggca gaaacgaaac
    61561 caagaatatc taaaaaagaa ggctgaagaa gaagcggctc tagctgagga gaaggaaaag
    61621 gaaagacaag ctcgaatggg agaagaatct gagaagtcag aggacaaaca ggaccaggag
    61681 agtgaaacag accaggaaga ttcagaatca gctaaggaag agtctgaaga aaaagtagca
    61741 tcctcagagg ctgacaaaga gaaagaagag aaagaagaac cagagtctaa agagaaggag
    61801 gaacaggata aaaagcttgc taaaaaggct acaaaggaaa aaccagccaa agcaaagatt
    61861 cctggtatcc atatcttgcg agccttcacg attttatttc caagtctgct tttattgatt
    61921 gtctctgcct acttgctcag tccttatgcg accatgaaag atattcgtgt tgagggaacg
    61981 gtgcaaacta cagctgatga tattcgacag gcttcaggca ttcaggattc ggattatacg
    62041 attaaccttc tgctagacaa ggcaaaatat gaaaagcaga ttaagtctaa ctattgggtt
    62101 gaatcagctc aacttgtcta tcaatttcca actaagttca ctattaaggt caaggaatat
    62161 gatattgtgg cctactatat ttctggtgaa aatcattatc ctattctttc cagtggtcag
    62221 cttgagacta gttctgtgag tctgaacagt ttaccagaaa cttatatatc agttctcttt
    62281 aatgacagcg aacaaatcaa agcctttacg tcagaacttg ctcaaattaa cccagaactc
    62341 aaggtggcta tccaaaaggt ggaattagcc ccaagcaagg tgacttccga tttaattcga
    62401 ttgactatga atgattcgga cgaagtcttg gttccgcttt ctgaaatgag taagaaattg
    62461 ccttattaca gtaagattaa gcctcaattg tcagaaccaa gtgtggtcga tatggaagct
    62521 ggagtctaca gctacactgt agcggataaa ttgattatgg aagcagaaga aaaagctaaa
    62581 aaagaggccg aagaagctga gaaaaggcag gaagaggaac gtaaacgttt agaagaagaa
    62641 cagaaaaaac aagaggaaga gagcaatcga aaccaaacga cccagcgctc atcgcgtcgc
    62701 taggttttac cttttctcct atagctcttt agttgccatg tttttacgtt taatatttga
    62761 catctgtttt tctttatgtt atatttgcaa tgtaatcgat tacaaaaaaa ttttttatga
    62821 agaaggtaac acatatgtca gatgaagtat tcttatttga agaaattgaa gaaatcgtag
    62881 cccctacaga tggtgaattt tgggggggag ttttacttgg aactggggta gttctcttaa
    62941 ttggagtagc ctgttgttaa aaagataggg agtgataatc atgcaagata actttttatt
    63001 tgaggaaatt gaagaaattt cagtaccagt tagtgatttt tcagctggac ttgcaacagg
    63061 tatcggatta ggtttagcaa tccttgctct tgctggttgt tgaagtttgt tcacttacta
    63121 atatcaagct ttttcaattt cattttagac agtcatttga attttccgta ttagtcttgc
    63181 agcaagagat taatagaatt agtcattatt ttattgattg cggactgagg gactagagta
    63241 tgttttactt agcccctctt ttatttatta aaggttaggt ttgttatgag aattgttgat
    63301 aagattaaga tactacctac tccttatgag ggacagtatc atctatatat accatccagt
    63361 aagaaacatg tattagttgg gaaacaggaa aaaaaatggt tagagcaact aataggtcaa
    63421 gaatttacca tatcggactt attagtgtta gtagggaaga aatattattt aa
//
LOCUS       DAVLCS010000009        51522 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLCS010000009 DAVLCS010000000
VERSION     DAVLCS010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51522
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.009"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(21..1562)
                     /locus_tag="VXC78_000641"
     CDS             complement(21..1562)
                     /locus_tag="VXC78_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0582759.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(1564..2046)
                     /locus_tag="VXC78_000642"
     CDS             complement(1564..2046)
                     /locus_tag="VXC78_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0582760.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(2046..2948)
                     /locus_tag="VXC78_000643"
     CDS             complement(2046..2948)
                     /locus_tag="VXC78_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HEV0582761.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFADEGVQVNLAVSLHA
                     PNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAE
                     LLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGTDID
                     AACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(2969..3499)
                     /locus_tag="VXC78_000644"
     CDS             complement(2969..3499)
                     /locus_tag="VXC78_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV0582762.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            complement(3657..4262)
                     /locus_tag="VXC78_000645"
     CDS             complement(3657..4262)
                     /locus_tag="VXC78_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV0582763.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(4403..5440)
                     /locus_tag="VXC78_000646"
     CDS             complement(4403..5440)
                     /locus_tag="VXC78_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0582764.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(5474..6409)
                     /locus_tag="VXC78_000647"
     CDS             complement(5474..6409)
                     /locus_tag="VXC78_000647"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV0582765.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(6962..8152)
                     /locus_tag="VXC78_000648"
     CDS             complement(6962..8152)
                     /locus_tag="VXC78_000648"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV0582766.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVINK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(8367..9710)
                     /locus_tag="VXC78_000649"
     CDS             complement(8367..9710)
                     /locus_tag="VXC78_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0582767.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(9850..10665)
                     /locus_tag="VXC78_000650"
     CDS             complement(9850..10665)
                     /locus_tag="VXC78_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0582768.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            complement(10717..12897)
                     /locus_tag="VXC78_000651"
     CDS             complement(10717..12897)
                     /locus_tag="VXC78_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0582769.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVADLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(13183..14109)
                     /locus_tag="VXC78_000652"
     CDS             complement(13183..14109)
                     /locus_tag="VXC78_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0582770.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKV"
     gene            complement(14102..14794)
                     /gene="ftsE"
                     /locus_tag="VXC78_000653"
     CDS             complement(14102..14794)
                     /gene="ftsE"
                     /locus_tag="VXC78_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV0582771.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(14812..15907)
                     /gene="prfB"
                     /locus_tag="VXC78_000654"
     CDS             complement(join(14812..15834,15836..15907))
                     /gene="prfB"
                     /locus_tag="VXC78_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV0582772.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(16015..16671)
                     /locus_tag="VXC78_000655"
     CDS             complement(16015..16671)
                     /locus_tag="VXC78_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0582773.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(17085..17795)
                     /locus_tag="VXC78_000656"
     CDS             complement(17085..17795)
                     /locus_tag="VXC78_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582774.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(17795..18559)
                     /locus_tag="VXC78_000657"
     CDS             complement(17795..18559)
                     /locus_tag="VXC78_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582775.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(18559..19515)
                     /locus_tag="VXC78_000658"
     CDS             complement(18559..19515)
                     /locus_tag="VXC78_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0582776.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(19519..20388)
                     /locus_tag="VXC78_000659"
     CDS             complement(19519..20388)
                     /locus_tag="VXC78_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0582777.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(20656..21816)
                     /locus_tag="VXC78_000660"
     CDS             complement(20656..21816)
                     /locus_tag="VXC78_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0582778.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(21917..22165)
                     /locus_tag="VXC78_000661"
     CDS             complement(21917..22165)
                     /locus_tag="VXC78_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV0582779.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(22244..22834)
                     /gene="clpP"
                     /locus_tag="VXC78_000662"
     CDS             complement(22244..22834)
                     /gene="clpP"
                     /locus_tag="VXC78_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV0582780.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(23008..23637)
                     /gene="upp"
                     /locus_tag="VXC78_000663"
     CDS             complement(23008..23637)
                     /gene="upp"
                     /locus_tag="VXC78_000663"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV0582781.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(23726..24193)
                     /locus_tag="VXC78_000664"
     CDS             complement(23726..24193)
                     /locus_tag="VXC78_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV0582782.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(24212..24769)
                     /locus_tag="VXC78_000665"
     CDS             complement(24212..24769)
                     /locus_tag="VXC78_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0582783.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            24894..25739
                     /locus_tag="VXC78_000666"
     CDS             24894..25739
                     /locus_tag="VXC78_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0582784.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            25798..26973
                     /locus_tag="VXC78_000667"
     CDS             25798..26973
                     /locus_tag="VXC78_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0582785.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            26993..27448
                     /locus_tag="VXC78_000668"
     CDS             26993..27448
                     /locus_tag="VXC78_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0582786.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(27468..28139)
                     /locus_tag="VXC78_000669"
                     /pseudo
     CDS             complement(27468..28139)
                     /locus_tag="VXC78_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819367.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            28305..29780
                     /locus_tag="VXC78_000670"
     CDS             28305..29780
                     /locus_tag="VXC78_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEV0582787.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMNFLVPNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSWSSSPNLCNQKGLE"
     gene            complement(29802..30746)
                     /gene="manA"
                     /locus_tag="VXC78_000671"
     CDS             complement(29802..30746)
                     /gene="manA"
                     /locus_tag="VXC78_000671"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV0582788.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(30878..31159)
                     /locus_tag="VXC78_000672"
     CDS             complement(30878..31159)
                     /locus_tag="VXC78_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV0582789.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            31224..32357
                     /locus_tag="VXC78_000673"
                     /pseudo
     CDS             31224..32357
                     /locus_tag="VXC78_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(32474..32821)
                     /locus_tag="VXC78_000674"
     CDS             complement(32474..32821)
                     /locus_tag="VXC78_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0582790.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(32932..34707)
                     /gene="spxB"
                     /locus_tag="VXC78_000675"
     CDS             complement(32932..34707)
                     /gene="spxB"
                     /locus_tag="VXC78_000675"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV0582791.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(34914..37157)
                     /locus_tag="VXC78_000676"
     CDS             complement(34914..37157)
                     /locus_tag="VXC78_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0582792.1"
                     /translation="MTEIVKASLENGIQKIRIQAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSICTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKKNAKLAISQLKKRGLGTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(37167..37538)
                     /locus_tag="VXC78_000677"
     CDS             complement(37167..37538)
                     /locus_tag="VXC78_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV0582793.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFSFACGMNMMHGKMIVE"
     gene            complement(37549..37944)
                     /locus_tag="VXC78_000678"
     CDS             complement(37549..37944)
                     /locus_tag="VXC78_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV0582794.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      38128..38226
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            38310..39101
                     /gene="thiD"
                     /locus_tag="VXC78_000679"
     CDS             38310..39101
                     /gene="thiD"
                     /locus_tag="VXC78_000679"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0582795.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(39311..39943)
                     /locus_tag="VXC78_000680"
     CDS             complement(39311..39943)
                     /locus_tag="VXC78_000680"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0582796.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(39936..40739)
                     /locus_tag="VXC78_000681"
     CDS             complement(39936..40739)
                     /locus_tag="VXC78_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0582797.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(40739..41263)
                     /gene="thiW"
                     /locus_tag="VXC78_000682"
     CDS             complement(40739..41263)
                     /gene="thiW"
                     /locus_tag="VXC78_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV0582798.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSATKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(41268..41960)
                     /gene="tenA"
                     /locus_tag="VXC78_000683"
     CDS             complement(41268..41960)
                     /gene="tenA"
                     /locus_tag="VXC78_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV0582799.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(41971..42621)
                     /locus_tag="VXC78_000684"
     CDS             complement(41971..42621)
                     /locus_tag="VXC78_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV0582800.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(42623..44008)
                     /locus_tag="VXC78_000685"
     CDS             complement(42623..44008)
                     /locus_tag="VXC78_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582801.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGIVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(44009..44569)
                     /locus_tag="VXC78_000686"
     CDS             complement(44009..44569)
                     /locus_tag="VXC78_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0582802.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(44832..44920)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(45129..45758)
                     /locus_tag="VXC78_000687"
     CDS             complement(45129..45758)
                     /locus_tag="VXC78_000687"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0582803.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(45760..46542)
                     /gene="thiM"
                     /locus_tag="VXC78_000688"
     CDS             complement(45760..46542)
                     /gene="thiM"
                     /locus_tag="VXC78_000688"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0582804.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPVVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(46824..47492)
                     /locus_tag="VXC78_000689"
     CDS             complement(46824..47492)
                     /locus_tag="VXC78_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV0582805.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(47707..47795)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(48047..49183)
                     /gene="lctO"
                     /locus_tag="VXC78_000690"
     CDS             complement(48047..49183)
                     /gene="lctO"
                     /locus_tag="VXC78_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV0582806.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(49808..51298)
                     /gene="lysS"
                     /locus_tag="VXC78_000691"
     CDS             complement(49808..51298)
                     /gene="lysS"
                     /locus_tag="VXC78_000691"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV0582807.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYTNLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(51426..>51522)
                     /locus_tag="VXC78_000692"
     CDS             complement(51426..>51522)
                     /locus_tag="VXC78_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV0582808.1"
                     /translation="YDLEPMAQQVIPKAAFGYIASGAGDTFTSFQ"
BASE COUNT        15152 a        11262 c         9609 g        15499 t
ORIGIN      
        1 tatttctttt actctcattc ttaagttaaa ttattaaaat cccatatttg gtctatccaa
       61 ccttcataaa agtctggctc gtggcagacc ataaggatag atcccctgta ttctttgaga
      121 gcgcgtttga gctcatcctt tgcatccaca tccaaatggt tggtcggctc gtccagcact
      181 aaaacgttgt tttcacgatt catcaagaga cagaaacgaa ccttggcttg ctctccccct
      241 gataatactt gaatctggct ttcaatatgt ttggttgtca aaccacaacg ggcaagggct
      301 gcacggactt ctgcttgatt aagggcagga aaggcattcc agacagcttc aagaggagtt
      361 tggcgattac caccttctac ttcctgctca aaataaccaa gttctaaata atctccacgc
      421 tccacttccc cagcgattgg cgagataatg cccaagagac tcttcaagag agttgttttt
      481 ccaataccat tagcaccaat aatcgcaacc ttttgattgc gttcgaaggt aagatttaaa
      541 ggcttagtaa gaggacggtc gtaaccaatt tgcaagttct tggcttggaa gataaagcgc
      601 cctggtgtac gagctggttt gaaatcaaag gatggttttg gtttctcact ttggagttcg
      661 ataatatcca tcttatccaa tttcttttga cgagacatag ccatattacg agttgcaaca
      721 cgggctttat tacgagccac aaagtccttg aggtctgcaa tctctttctg ctggcgttcg
      781 taggctgcct ctagctgaga tttcttcata gcataaactt cttggaactg gtagtagtca
      841 ccagagtaac gcgtcagctg ttgattttcc acatgataga caatattaat aacgtcattg
      901 aggaatggaa tatcgtgcga aatgagaaca aaggcattct catagttttg gagatagcgc
      961 ttgagccaat caatatgctc agcatccaag tagttggtcg gctcgtccaa cagcaagata
     1021 tcaggctttt caaggagaag ttttgccaaa agcaccttgg ttctttgccc acctgacaaa
     1081 gaagttacat ccgtatccat gccaaagtcc ataacaccaa gagcacgcgc tacttcgtca
     1141 atcttagcat ccaaggtata gaaatcacga ctctccagac ggtcttgaag ttctcctact
     1201 tcttccatga gagcatcaac atccgcgccg tcttcagcca ttttcatata gaggtcattg
     1261 atacgagctt cagctttgaa aagctcatca aaagccgtac ggagaacatc acgcaccgac
     1321 tgtctttcag caaggacaga gtgctgatcc aagtaaccag ccgtcacata tttggaccac
     1381 tcaacctttc cttcatctgg cagcatttta ccagtcacga tactcataaa ggttgatttt
     1441 ccttcaccat tggcaccgac caggccgata tgttctccct tgaggagacg gaaggacaca
     1501 tcttcaaaaa ttgcacggtc accaaaaccg tgactcagat ttttaacttc taaaatactc
     1561 attttaattc cttatcttgt ttttatgtaa tcgtttataa aggagccaag ccagatagcc
     1621 acccaaagta ttggtccaca aatcatcaat ctcaaagacg cgattgaaat caaagaaaaa
     1681 gtccaagatt aattgcgtac actcgattcc aagactcaca agaaaactaa aaagaaggac
     1741 cttttttgtt ttccgcaaat ttggaaatag ataaaggagt tggaaaatca gaggaaaaaa
     1801 caagaagaca ttgaggacat tttgtaaaaa aatccaacat aattgtccaa tgtcactcac
     1861 ttcgcccagt ttccagagag aattgaaagg agtcaaaaga aaaaccaggc gtccaagatg
     1921 ctgaatacct ggagttccca ctcccacggt agattgttct tgaggagtaa agcaaaaaca
     1981 gacaatgcaa atgctataga aaatgactcc ccagaccaaa atatgattat aagtcttctt
     2041 catcattaag gatttaccgc tgcgactgcc ttctggcggt cacgtttcat tgtgttagag
     2101 cgcaattgtc cacaagctgc gtcaatatct gtaccatgct cttgacgaac cacacagttg
     2161 accccttttt tcttaagcgt atcatagaaa gccaacacgc gctctttggg actacggcta
     2221 tattggtcat gctcactaac tgggttataa ggaatcaagt ttacataaga caatttcttg
     2281 atgttcttga gcaattcagc caattccaag gcttgttcta caccgtcgtt gacttcatta
     2341 agcatgatat attcaaaggt tacacgacgg tttgttgtct caatgtagta ttcaatagca
     2401 gcaaagagtt tttcaatcgg aaaggcacgg ttaatcttca tgatacttga acgaagttca
     2461 ttgttgggtg cgtgaagaga cacggcaaga ttgacctgaa ccccttcatc agcaaagtat
     2521 ttctgaacca gcatgatttg cgctacgatt tcaccgttat tgaggtcacg ctgcttctta
     2581 atcaaaccag aggcacagaa ggtacaaccg atattacagc cgacctgagt ggtcacacag
     2641 acagataaac catagtgttg acgcatgagt acagtctcaa ttaacatacc gtcaggcaat
     2701 tcaaagagat atttgactgt accatcagca gactcttgca caatacgttg tttcaaggga
     2761 ttgaccacaa actggtcatt gagcttagca atcaaatcct tggaaaggtt ggtcatttct
     2821 tcaaatgact gcacacgttt acggtagagc cattcccaga tttgatctgc acggaatttc
     2881 ttttctccct gctccaatac ccattcctgc atggtttgat gtaccaaact atgaattgag
     2941 ggtttcattt cttctcctta ttctctactc acttctgacg aatgacaaaa tgacgttgtt
     3001 ccttgtcctc tttctgagaa tgctggtctt tctgacgacg tctatttttc ttatctgcat
     3061 tcgactttcg tttagtttga gtcggtttct ttccttttct agaaggtgtt tcttcttccg
     3121 tcttacgcat tttcttgtca aatgatgctc gcttaggggc ttcattttct aagacaaaat
     3181 aggcacaacc ataactacaa tactctaaaa ggtagtcttg taaacgactg attttttcaa
     3241 gtttttcttc tgttcggtca tccttgtaaa aacctcgtag gcgaagctgt tcgttgctcc
     3301 agtcccccac gatataatca aacttggtta agacttctga aaaacgctga ttaaaagtcg
     3361 tcacatcaaa ggcatccttg atattttcaa ccaaggaaaa agctatccct tccgtttcga
     3421 ccttgtcccc gtgtaaatgg aactccggac caggaaactt gttatagttg tataattcag
     3481 gtgcaatttc ttttcgcata gatatccttt ttccacgatt acttaatact ttattctacc
     3541 ataatttcta gcagttagca cgtttctcat aaaaaatgaa aaaagtctaa cgattttgtc
     3601 agaccagaat cttataacct aaaaaagaga agaacaattc ttccctccaa ctatcattat
     3661 ttagcagctg cgtacaattc atctacttta ttccagttga ttactgaaaa gaaagctttg
     3721 atgtagtcag gacgcacgtt gcggtatttc acgtagtaag catgttccca aacgtccaag
     3781 cccaagattg gttttttacc ttctgagatt ggtgtgtctt ggtttgctgt tgaagtcact
     3841 tcaagtttcc cttctttgtt gacaaccaac catgcccaac ctgaaccaaa acgagttgtt
     3901 gctgctgcag tgaaggctgc ttggaattct tcaaatgaac caaatgttgc atcgattgct
     3961 gctgccagtt ctgctgaagg agctgttttc tcgggagtca tcaattccca gaaaagagcg
     4021 tggttcaagt gtccgccacc attgttgata agtgcttgac ggatatcagc tgggatagat
     4081 tctacatcag caagcaaggc ttcaaggtct tcaccgattt cagggtgttt ttctaaagct
     4141 gcattggcat tgttgacata agtttgatgg tgtttgtcat ggtgcaaatg cattgtttcc
     4201 gcatcgatgt atggttccaa agcgtcgtat gcatatggaa gttctggtaa gataatagcc
     4261 atctgtaata cctctttttc tttctatatg aaaatgataa cgcaaacatt cacttttttc
     4321 aagttttttg cttatagata agcaaatcag caagaaaccc acgacaagat aatcctgacg
     4381 cgggttgtag tttcaacaaa tgtcaattga cctgactagc aatctgtaag agtgcctttt
     4441 caaaaaggaa acctttttca taaagacctg tcttaatctg atagtctgtc tcaatcaaat
     4501 aggaaatagc ttgcttcaga aagctcaaag aaagtcctct cgaatctctt aatgcaaact
     4561 tgatttgata aggatttggg ttacgtccca gataactacc taaactactt gcaatctgcg
     4621 attctgtttg gccagactcc gccaaaatct tcacctgagt aaaagtccga aattgtccca
     4681 gcatgactgc aattagtttg atttcatctt ccccttgcaa ggtcaagtct ctcaccaaat
     4741 cgcgcgcctg atccatcttt ttagtcagaa taaactgagt taaatcaaaa atattgtcct
     4801 gcaaggtctt gggaattgcg ttaacaatat cctcttcctc gataacagaa tccgccttat
     4861 aggactgtaa aaagagaaga tttttctgga tttcgctaaa ttgaaacccc gacttgatga
     4921 ggagattttc aaaagaatga ttggtaaact gcagaccttg tttctgactc cacttttgga
     4981 aatactggcg caattcttgt tcttttactt ctactgcatc gaaggccttg gcatcacgct
     5041 taagtaattt gactaaccgt cttttgctat ccagctttcc ttctgcaaag attatcaact
     5101 tggttgttgg agaaggattg tcaaggtatt cctcaaatga cttaagctca tcatctgtca
     5161 aaaagcgttt cttagcagtc gtgatatcca taaaataatc taatatcacg attttctcat
     5221 ccgcaaagaa aggaaggctg accaactcca gttccacatc cttgtaaact acttctttca
     5281 tatcaaagta ggcaaagttg aggtcagcag aatcataccc aatctgtttc aacacttgac
     5341 tcttcatcac ttcaaactga ccctgatctg tccctgtaaa taggctcagg ctcggtaaat
     5401 ttgataaagt caacttctga ctttcttcaa tggctagcat cgtctctcct ttcttcagat
     5461 ttttcgattt aatttagtca atatagcgca atttcccacg gaaatcttct aagctctcgt
     5521 agcctttttc caccatgatt gctttcagtt cattggtaat gcggtcaaaa gcactgacgc
     5581 cttctttgtg aagggtcgtt cccacctgca ccatacttgc tccacagagg atgtgttcaa
     5641 aggcatctcg accagtcaga acgccacctg ttccgataat ttggatttga ggatttaaac
     5701 gttgataaaa ggcgtgaaca ttggctagag cagtcggttt gatgtattct ccaccaattc
     5761 caccaaaacc attcttaggc cgaataacga cagattcgtc ttctatatag aggccgtttc
     5821 cgatagagtt aacgcagttg acaaacttga gcggatattt gttgaaaata gctgccgctt
     5881 gatcaaagtg aacaatatca aaataaggtg gcaatttaat tccaagaggt ttggtgaagt
     5941 aagcaaacac ttctgccaaa atccggtctg ttgtctcaaa atcataggca atctgaggtt
     6001 tacctggaac atttggacag gaaagattta gctcagtcag accacgaaaa tcactctctt
     6061 gaactttttt caaaatagta tgggtttcct ctggagacat gccgaccaga gataagaaga
     6121 aagttcggtt cgactctttt tcctgcaaat ctaaaagata atccaaataa tagtctaagc
     6181 cattatttgg caagcccata gagttgatgg aaccaagtgg aacatcttgg tagcgtggct
     6241 caggattccc ctgacggaag tccaaggtcg ctgtcttagt aacaaaggtt cctgccgctg
     6301 agtttttgac ctcttctaac tcctctatcg tcatacaagc cacacctgct gcattcatca
     6361 agcaattgtc aaactcaaaa ccagcaattt gtgttttcgt tgataccatg attctaatcc
     6421 tccagatttc ttttattgct aatattatac cataatttta attctaggtt tactagattc
     6481 tgtggttcta tctatttatt cggaaaagaa agtctagtac agaagtcatg ctatgaaaac
     6541 agctagtgta ttggaagttt gaacaaggct tgggtaacag acttttgaat gaagtccaag
     6601 caacaaggag aaatctcaac catgagtcca ttccatgact ctgttgctct agaaaacctt
     6661 gcaatagtca agtgataacg aataaaactt tggattgaaa tatccccatg attatctatt
     6721 acgaggagaa atctcaacct ttatcatttt taaagaaata tagtaaaatg aaacaagaac
     6781 aggagaaatc gatcaggaca gtcaaattga ttgctaacaa tgttttagaa gttgaggtgt
     6841 actattctag tttcaatcta ctatacatgt aaatctctac tttcgcaaaa tggattttca
     6901 gaacagtatc ccagtatagt taaaaactat aaaaaagaga ggacgttccc ctcttaaaat
     6961 cttattttac tgcttctttc aaagcatcta ccttatccaa acgttcccat ggaagatcaa
     7021 tatctgtacg tcccatgtga ccgtaagccg atgtttgacg gtaaattgga cgcttgaggt
     7081 ccagcatttg gataatccct gcagggcgaa ggtcaaagat ttgacgagcc gctttttcaa
     7141 gttgactttc agctactgtt cctgtaccga aagtatcgat acgaacagaa acaggttgcg
     7201 caacaccgat agcataggcc aactgcactt ctgccttctt agcaaggcct gctgcaacga
     7261 tattcttggc aatatagcga gccgcataag aggctgaacg atccacctta gtcgcatctt
     7321 taccagagaa ggcaccacca ccatgacgag agtagccacc ataagtatct acaataatct
     7381 tacgaccagt caaacctgag tccccttgag gaccaccgat tacaaaacga cctgtcggat
     7441 tgataaagaa ttttgtctta tcatcaagat aagaagatgg aataacttct ttgatgacct
     7501 tgttaatcac atcttgatgg atttgttcat tagtggcctc tggatcatgc tgagtagaaa
     7561 taacgactgt atctacacgt accggacggt cattttcatc gtactcaact gtaacttgtg
     7621 attttgcatc tggacggaga tagctaattt ctccagactt acgaagttct gccagacgac
     7681 gaaccaattt atgactgagt gcaattggca atggcatgag ctcttctgtt tcatctactg
     7741 caaatccaaa catgagccct tggtcacctg ctccaatcaa gtccagtgga tcttgatcag
     7801 catttccacg aacctccaag gcttcgttaa caccttgagc gatgtcagga gattgttcca
     7861 ccaaagatgg gtgtactccc accgtctcag cagaaaatcc atattctgta ttggtataac
     7921 caatctctgc aatggtatca cgaaccacac ggttaatatc cacataggca tttgtagaaa
     7981 tttcaccaaa aacgtggaca gaaccagtat atacagctgt ttcagcagca acgtgcgcct
     8041 ctggatcctt tgctaaaata gcatccaaaa tcgcatctga aatttggtct gcaatcttat
     8101 ccggatgccc ctcagataca gattcagacg tgaataattt acgttctgac ataaaaatgt
     8161 ccccccttaa aaaatattgt tatagagtta caaagtactg ataggaaaac tcttcgtaat
     8221 aaatacctac catcttatcg ggactatata actttatcat tataccattt ttaatcgcaa
     8281 tttgcagtct ttaatgtagt gtttcggttt agatagttcg ttctcataaa gcaaaaagtt
     8341 ggagctcaat actccaacaa tttctattaa aatgtttggc gtttagcttt acgctctgca
     8401 cgaccgcgag cgcgattttc agcacgcttg gttttacggc gcttttcatc aaccgcccat
     8461 tgaattttct tcttataacc cggtttgact tttttctttt tctttttaac caaaccaatc
     8521 atttcgatat caagtttatc ttgttttttc tcacggttgg cacgacgatc acggtcatag
     8581 gtatcttgaa attccccgtc tttgaccatc ttaggactaa acttgattcc caatttctcc
     8641 aactcacgga tatccgagtc atcacttggc tgataaaggg taatagctgt acctggtagg
     8701 ccatttcgtc cagtacgacc aacacgatga acaaaaaaag ataagtcttg cggaatggca
     8761 tcattgatga catggctgac accttcaatg tcaatcccac gcgctgctaa atctgttgcg
     8821 acaatatact caaaatccag attttgcacc tgattcatga ttcgcttgcg ttcacgaggg
     8881 gcaatatctc catggatttt tgcaaccttc aagccttgag cagtcagata tgaatgcaat
     8941 tcatcagcac gcgttttagt gttaacaaaa atcattgcca aatacggctg catcaactga
     9001 gtcaactggt aaatttgagc attcttatca tgtcccttgg tcgaaatcaa ccaattatca
     9061 atggtgtcag aaataaccgt tttggtctta attttctcca taacaggatt tgataagtat
     9121 tttttcaaga atggttgcag tttttgtggg atagtcgctg agaagaccat gaattgcaag
     9181 tcttttggaa gactgccagc aatcttatca acagtttcca agaatcccat atccaaggtc
     9241 atatctgctt catcaacaac aaatgtcttg gctttatgaa tagctaaatc accagattta
     9301 accaagtcgt agatacggcc tggtgttcca ataacaatat gaggctgatt gctttccaat
     9361 ttctcaatct ggcgagcctt atccgtacca cccacataat taaccacacg aacttcgaca
     9421 tctgagtgag ctgaaatctg acgcgctact tggtaaattt gagtagccaa ctcacgactc
     9481 ggtgcagtaa tcactgcttg tacactatcg ctagcttcat ctaattgctg gaaaatcggt
     9541 aacaagaaag tatgagtctt acctgaacct gtttttgatt ctcctactag gtcacgacct
     9601 gccaaaacaa taggaatcaa cttgtcttgc acctctgttg gagttgtaaa ttttaactcc
     9661 ttcaaggctt ctctaatata gtttttaaat tgaaatttcg taaatgacat aacatcctcg
     9721 attctatcta tcttatcaat tataccatat tttattccat tacagtagtc tcacttattt
     9781 aggctatttc cagtagcttc tctagtaaga aaaggctgga attttatagt tccaacctct
     9841 tttcagttat tatttccagt ttaatatagc attcaagcca tagtgatcac tcacttgtgg
     9901 actcttgtta ccatcaaata cgacatgtaa attttccacc gctaactctt tggtagtaaa
     9961 gacataatcg attcgaaggg gttcagtgtt ccctttccag ccatcaattt caggcggaac
    10021 agtatagcta ccacttttct cttgagcaac ttcaaatgcg tcttgtaagc ctaatggact
    10081 agctaaaata gcttggtaac cttcctgacc tgctgggttg ttaaaatctc cagctagtaa
    10141 aagtggcttg ttcaattttt tcaagacagc ctcaaatcgt gcccattctt cttggaaacc
    10201 tttatcccac caagagagat gaacactggc aactgctagc tccttgccat cgactacagt
    10261 ttcagctagg gcaacacggc gagtatgata gtctgttgga tcatccacat ctgaaaccaa
    10321 aatttctctg gcttcaatag gtgttttaga caagatagcc acaccttcgt ggtagcggtc
    10381 atagccgata tggttataag cccaggtcca gtagtaattt ttcccttgct ctaacaactt
    10441 ttcaaccaag agtctaacat aatggtcttg gtgaataggc tcagctgctg gcaaagcttg
    10501 ataaaggtca ttaacctcca cctctgacga ggtcatctcc tgattgattt cttggaaaca
    10561 aatcaaatca tagtcctttt caagaatatc ttcaagcaaa atctggaatt tttcctctgc
    10621 ttctttctcc atccaactgt gagtattgag tgttaaaaat ttcattcttt tctcccaaaa
    10681 taagaggttg gaatacagct tccaacctca agtatattac aattctactt tagcaactgc
    10741 tgttttagct gcaagagaac ctgttttttc taatttaact gatttaattg catcaccatt
    10801 tgtgaagaca actactgttg aagtttcacg tcctgctgca cggatagcat ccaagtcagc
    10861 tgtgacaagg agatctcctg ctgcaacttt ttgtccttca gcaacatgaa ctgtaaatgg
    10921 tttaccttca agacttactg tgtccaaacc aatgtgaacc aatacttcaa gacctgcttc
    10981 cgtcacaata ccaaaagcat gttttgttgg gaagatgctt gacacagtac ctgaaactgg
    11041 agatacaatg tttccatttg caggttctac tgcaaatcca tcacccatca ttttttgagc
    11101 aaatactgga tcctttactt gttccaaagc aacaacttga ccgtctgcta ctgagtaaac
    11161 ttcctcagta agatctttga agtgaacagt gttttgttgt gcttcagtca tttggcttgg
    11221 aagagtttca ggaatgattt cacctgaatc aaggatatct tggatatcag atttcaaaat
    11281 gtcagctttt ggaccgtaga tagcttgaac cccttgtcct ttcatcacaa gacccatagc
    11341 tccttctgct ttccattgct ctgcatttcc tactttatct gcatctttaa cagttacacg
    11401 aagacgagtc atacatgcat caacatcaac gatgtttaca cgtccaccaa gaaggttgat
    11461 aatgtttaca gcttgagagc ctgctgcaac tttcacttcg ctgctggttt cttctgaacc
    11521 ttcagcagtt tcgtagtttc cgttgcgccc tggagttgcg tagttgaatt tttgaatcat
    11581 gaagtttgcg ataaagtaca tgattacagc aaagagaaca gttacccaaa cgaagttaac
    11641 gatatccata ccaataccag cactgattgc aataggtgta cgagtcaaga actcgattga
    11701 accgaatgag tgcatacgta ggtttacgac gtcagccata gcgaaggcag caccttgaac
    11761 aagtgagtaa acaagataca taggtgttgc gatgaacatg aacatgtatt cgattggttc
    11821 agtaacccct gtcaagaatg ttgcaagagc tgttgcaatc atcatacctt tgtatttatg
    11881 tttcttgtca gcatcaacat tacggtagat agcaacaatc acacccatca agataccgaa
    11941 tgaaccgatc atttgtccaa ctttgaaacg agctggatgt actgtatcta acaagtgttg
    12001 atattgacta gcatcagtac ctttaaggtt tacaaggtct gctacccatg caagccatag
    12061 tgggtcttga ccgaatactt gagtaccttt agctgcacca gttaaaatgt cataagtacc
    12121 accaagagct gtgtagttca ttgggatagt caacatgtgg tgaagaccaa atggcaagag
    12181 caaacgttcc aaagtaccat acaagaatgg tgcaagaatt ggagcagttt cttgtgagtt
    12241 ggcaatccag ataccgaagt tattgatacc tgtttgaact actggccaga aagcagcaag
    12301 tagaattgca gcgattgctg aacgaagaat aactacaaat ggtacgaaac gtttcccgtt
    12361 gaagaatgaa agtgcatcag gaagtttacg gaagttgtag tatttgttgt aagcagttgc
    12421 ccctacaaaa cctgagataa tccctacgaa tacccccatg ttcaaggctg gagcttcaag
    12481 aacactgata aagtaatcag caactttgat tgaaccacca aagaaagtag ttaccatagc
    12541 atctggattt ttcaacatat cgcctgatac accaaagatt gtaccagtga tacggttaat
    12601 caagatgaag gcaagaccag cggcgaaagc accaccagca cgttctttag cccagcttcc
    12661 tccaatggct agggcaaaca aaatgtgaag gttaccgata accccccaac cgatttgctc
    12721 aagaattcca cctgtgatga caagtggtgc aaaggttggg ttaatcatca cgatagactt
    12781 accgattgaa atcatcaaac cagcagccgg cataaccgcg ataactacca tcaaagcctt
    12841 accgaatttt tgccaaaatt cgaaagacaa gacatttttg aatgtatctt tcatcattca
    12901 aatctccttt atttttattt aggcaaacgt tttacgaaaa cgtttgcact ttctatgatt
    12961 taattatacc actttaattt tttttgtaaa ggcttttata aaaaaattac acttttttct
    13021 aaaaaatttc tagtgcgcca aatttcaagt tcaaattagc catcaagaag tcttctctgg
    13081 gggacttctt tggaagctct tttcttctgc gcatctcttt tcaaaaactc ttgtagcaaa
    13141 aaaggagatt ttacaatctc ctcataaaag cagctatttt acctaaacct tcaagaatcg
    13201 gcgcatggat attcctgatc ccaatgaacc aatgaaaacc ccaatcacaa atagtagggc
    13261 aatcatcaac ggactaaata aatctggact aatcatggat agattttgcc ctaccaacga
    13321 tttgttgaca gattggtaaa caatttgata aacaataaag accaaaacag atggtgcgat
    13381 agctcccaat aaaccgataa aggctccttc taacaagaac ggtccacgga tataactgtt
    13441 tttagctccg accaagcgca tgatttgaat ttcgcgactg cgggaaataa tggtaatacg
    13501 aatggtattt gaaatcaaga aaactgcgat aaaaattaac aaagcagcaa tccctagtcc
    13561 ccaaacacgg ataaatgaag ctaacttgaa gagtctttct gtattggcac cgccatcttg
    13621 aacctcagag acaccttcaa tttttttagc atcttcggct atagttttta catcatttgg
    13681 agtgtttgcc tctacaatat aggcatcata gagaggattg gcatctcctt caaagatttt
    13741 ccagttatct cccattatct cggttaattt ttcatattgt tcttctttac ttgaaaaggt
    13801 aacactttta accgtagaca tgttcttcaa agaatcatat accttgtggt agtcattatt
    13861 tgtaacagtt tgaccttctt tttcaattgt ctgactatta tcttccacat cctttcggat
    13921 ataaactact acacggacat tattttcaat atctgtagct agtttcgctg tattgaaaat
    13981 aacagatgca aatattgcca ccaaggtcaa agtaatcatg actgaactga cagcagctac
    14041 tgtcatccaa ccatttcgtt tcaaactttt taaggcttca aataaatggc gaaaaaatct
    14101 actaatcatc gtatccatac tctccttttg attcgtcacg aacgacacgg ccattttcaa
    14161 tggcaatgac acggtggcgc aaggtattta caatctggct attatgagtc gccatcaaaa
    14221 tagttgttcc ttgtaggtta atccgttcca aaagattcat aatttcccat gaattatccg
    14281 gatccagatt tcctgttggc tcatcagcta tcaatacttt gggattattt acaattgcac
    14341 gcgcaatcgc aatccgctgt tgctccccac ctgagagttc atttgggaaa gaacgaacct
    14401 tatgcttcaa tccaaccaag tccaaaactt ccatcactcg tcttttgata ttacggcgat
    14461 tttccccgat tacttccata gcgtaagcaa tattttcata gacagttttc tttggtaaca
    14521 atttataatc ctggaagaca accccaacac tacgacgtag aagcgggata tctttctttt
    14581 tgatcttaac cagattaaaa ccagcaactg ataggcttcc tttatcgatt tttacttcac
    14641 gatacagaga acgaataaaa gttgacttcc ctgctcctga aggtcctacg atgtaagcaa
    14701 attcccccgg ttgaacgcta accgaaacac cgcgtagagc agtcgttccg ttgtcgtatt
    14761 ttttaacgac atctctcatt tcaataattg acatgtgagt tcctttctat cttagctaat
    14821 tcgccacttg agataagcat cgataaaacc atctaagtcc ccatccataa ccttatctac
    14881 ctgagcaacc tcaaagctag ttcggtgatc ttttaccata gtataaggcg tgaagacata
    14941 agaacggatt tggcttcccc aagtgatctc ctttttctca cctttgagag aatctacctc
    15001 tgcagccttc ttctcttgct ccatttgata gagcttagcc tgcaacatct tcatggcacg
    15061 atctctattt ccatactggg tacgatccac tgttgattgg acaacaattc cagttggaat
    15121 gtgggttaaa cgtacacctg ttgaaacctt attgacgttt tgtccaccgg caccacctga
    15181 acggaaggta tccatcttga tatcatcttc acggatttcc acttcaatag tatcatccaa
    15241 ttctggcatc acttctacag atgtgaaaga ggtatggcga cgtttggcag agtcaaatgg
    15301 tgagattcgc actaagcggt gaacacccat ttctgacttg aggagaccat aggcattagg
    15361 cccttcaaat gataaagtta ccgacttaat accagcctca tcacctgctt ggtaatccaa
    15421 cacttccact ttaaagcctt tagcattacc ataacgagta tacatacgaa gcaacatatc
    15481 accccagtcc tgcgcctcag taccaccaga acctggatgg atttccaaga tggcattgtt
    15541 gtggtcataa ggttctgaca agagtagagt catctcgtag ctggtcatta tcttatcaag
    15601 ttcggctaac tgcgctacca gttcatcatg cactgactcg tcttcagcca aaaaatccaa
    15661 taaaatttcg acttcatcct gcaactcttc catcttatgg aaggtattgt aagtgttttt
    15721 taattcattt aattcttgcg acgttttttg ggctgcaata ttatcgttcc aaaaatcagg
    15781 ttctgtcatc ttgttttcca agatggcaat ctcttcctct agcccttcga ggtcaaagag
    15841 accccctgaa agaagctaat ttttcacgat ttgcgtcaat tttctgacga attactgaaa
    15901 tgtccataaa tactcctttt ttacattatt tcattatagc atattttatc atttctttcc
    15961 atctttttct ctaatcccct tttcatgaaa aaagaagcct ttgggcttcc cttcttacaa
    16021 gacttttgct gaagtgcgag cgatttcttc cacttgaata ccatttgctt caaatttttc
    16081 tttcaaggct ggtaaatcaa ttgatccatc gatttgcact tcgataatca ccttaccatc
    16141 cttacgcgga atattgactg tatgggagat attcaaattt tcttctacaa tcaaagaaac
    16201 aatttttcca agaacaccaa cttcatcttc tgtaacaaag cgtacacgaa tcccttcttc
    16261 gccataacct gcaatttcaa gaaaggcttg gaaaacgtca cggtcagtaa taactccgta
    16321 tacttgatgg ttatctacga cagggagaat actaatctta tttttcaaca tcagataagt
    16381 tgcatcttct agactagcat agcctgagac agtgacaaca tcgcgaatca tgacatcttt
    16441 tacttttgtc ttattcagaa gataattcat ctcatagata gaaagacttg ttgctttaga
    16501 tggacttgct tgtgcaatgg ttccctcagt caccaaacca actaattgat cattttcgat
    16561 aacaggcaga cggtgcaaac cttgctctct catcaaatct gctgcatgag atactgttgt
    16621 atctggacta atataaacta ccttgcgggt cataaaatct ttaactgcca tgagacttct
    16681 ccttttctat tcttatccct attatacaat ctttttgtaa atctatcaaa cgcttacatt
    16741 tctttttcga aattcagaaa agtatgaata agctagcaaa aagagctctg aaatcgagct
    16801 ctgtgaatga aggtaagaaa tttttcattc gattttttca attattagaa attaagcttt
    16861 caatgtagat gcagatttgt ttgcaatctc aatctaccga ctaaaaaggt cccccggact
    16921 atattgatga ttacttcgta atctccatct gccgactaaa acaatccact ggatttgatg
    16981 attgcttcgc aatctttatc tgcaacctaa actagtctcc cagactataa tgatgattac
    17041 ttcgtaatct tcatctgccg actaaaacaa tccactggat tgttttagcc acctagatat
    17101 gcttttctga cttcttctga tgaggcgagt tcttttcctg ttcctgatag gacgattttc
    17161 cctgtttcca gtacatatcc tcggtcagag attgcaagtg ctttattggc attttgttca
    17221 atcaagagga cggttgttcc ttgcttctga atatcttgaa tgatatcaaa aatctcttgg
    17281 atgaagattg gggcaagtcc cattgatggt tcatctaaaa gaagaagttt tggtgttgac
    17341 ataagagcgc gtcccatggc aagcatttgt tgttcccctc ctgaaagagt agctgcatct
    17401 tggttcttac gttcttcaag acgaggaaag cgtgagaaaa ccttcttcaa gttagcttga
    17461 ttttcttcac gatttttctt taagaaagct cccatttcaa gattttccat aacagtcaag
    17521 ccaggaaaga cgtggcgtcc ttctggaact tgtgaaagac cacctgccac aattttctga
    17581 gctggcattt tttggatttc ttgacctaaa aattcaatct ttcctgaact tggtcgaacc
    17641 aaacctgaca aggtgcgaag aatagttgtc ttacctgcac cgttggcacc gataagggaa
    17701 acaacttctc cttcattaac ttcaaagctt acatcacgga ctgcttggat cataccgtaa
    17761 tgcacagaaa gattttcaac ttttaacata gacattaggc ttcacctcct agataagctt
    17821 cgataacgcg tttattggtc ttaatttcgt ctggagttcc ttgagcaatt aaacggccat
    17881 attcaagtac gtagatacgt tctgttactt ccatgaccag attcatatcg tgttcaatca
    17941 acatgattgt aatcttaaat tcatctttga tacgacgaat taactcagtc aattcggctg
    18001 tttcctgtgg gttcatacct gctgctggtt catctaagaa gagaatttta ggttccgtag
    18061 caagggcacg aacaatttcc aaacgacgtt gttgtccgta ggaaagattt ttagcaagag
    18121 tctctgcatc accatctaaa tcaaagattt tcaacaattc caaagcttta gcctttaatt
    18181 ctttttcact cttgtaaaaa gctggtaagc gtaagaaact agtaaaaaca tgttgtttgt
    18241 gatggtttcc aaaagcaatc aaaacattgt ctaaaactgt taaatcttta aagagacgga
    18301 tattttggaa agtacgtcca agtcccaaag aggcaatctt ataaggtgat ttcccattca
    18361 aaaggtgacc atctagggtt actgttccct cgcttggttc ataaacaccg gtcaaaaggt
    18421 tgaaaagggt ggttttccca gctccgtttg gaccgattaa tccaaccagt tccccttcgt
    18481 tcaattcaag agtcacatct ccaacagctg ttagaccacc aaaatgtttg gttaactgtt
    18541 ttacttcaag taatgccatt agttttgttc ctccttctta gattttttaa agaaacgtga
    18601 taggctcagt tcccatgttc caaggagtcc acctggtctg aaaatcatta ccaataccaa
    18661 ggccaaagcg taaataatca tacgcacact agcaacatct tggagaagca tattcaaaat
    18721 tcccagaaca atagccgaaa caatcgcacc tgtaatggaa ccgagtccac caaatacaac
    18781 aataatcaaa acgttgattg agttgatgaa ggtgtaatct ttcggtacaa cagacccgat
    18841 aaatcctgcc tgaagtgacc cagcaatact tgcagtaatg gcaccaaaga caaaagcgat
    18901 gattttaatt ttagtcgtat taaccccaac tgactcagca gcgatttcat cttcacgaac
    18961 agagagggtt gaacgaccaa ttgggctacg caagaagttc aaggttgcaa tggttgtaat
    19021 cacgacaaag aagtaaacca tttgccaagt tgtaaagtta ggaatcccta agatacctgc
    19081 cgcaccattt gtaaggcttc caccattgat gataaagata cggataattt cagaaacacc
    19141 cagagttgct accgcaagat agtccccctt caagcgcaag gttggaatgc cgacaagtaa
    19201 ggcaactgct cctgaaagca aagcccctac aagcatagct ccaaagaagg caccgtaggt
    19261 tggtaattta gaaccaataa tagctgctgc ataggcacca atcgccatga aaccagcatg
    19321 accaagtgaa aattgtcctg aaaaaccaac gattaagttg agaccaacag ccaaaataat
    19381 attaattcca atttgctgta aaatctgtac atagaataga ttaagtactc cgactgaaac
    19441 cagtacacta atcaagctat agccagctaa caaaaggagt aaccatagaa tattaacttt
    19501 taaattttcc ttcatcgttt acaccttctc tttcacattc ttaccaagga taccagctgg
    19561 gcggacaatc aagatcaaca acaagattcc ataaacaatg gcatcacgga aatctgacat
    19621 cccaaaggca gtcgcaaagg tttccaatag accaatcaca aaaccaccaa gagccgcacc
    19681 aggaataatt ccgataccac caagtactgc ggcaacgaaa gatttaagac ctggagtaac
    19741 ccccatcaaa ggctcaagag agttataata aagagcaatc agaacaccag ccgcacccgc
    19801 aagagcagaa cccaaagcga aggtaaagct aatcgtacgg tttacattga tccccatcaa
    19861 ttgcgccgcg tcgctatcta ctgatactgc acgcatggct ttccccatct tagtcttttg
    19921 gacaatgact tgtaacaaaa tcatcaaaat caaggaaata gccaaaatca ttaactgcac
    19981 atttgttaag ctaattggtc ccaaatcata tcgaactgtt tgaatcgctt gagggaaggc
    20041 acgggtattg gcaccaacca gatagaccat tccatactcc aataggaaag aaaccccaat
    20101 agccgtaatc aaaacagcaa tacgagtaga gtggcgcaaa ggtcggtaag caagaaactc
    20161 aatcacgaca ccaagaatag ctgtcgctag catagctaca ataagcgcta caaagaaatt
    20221 catttggaaa gaattgatca agaaataacc gataaaggct cccatcatat aaatatcacc
    20281 atgggcgaag ttgatgagct tgataattcc gtaaaccatg gtatatccta gggctaacag
    20341 cgcgtaaaca ctacctagaa tcaaaccatt tacgagttgt tggagcataa gattcactct
    20401 ttctatttat aattccgagg ggtttccctc actttttgat aggttcttat actcaatgaa
    20461 aatcaaagag caaactagga aactagccgc aggttgctca aagcactgct ttgaggttgt
    20521 agataagact gacgaagtca gtcacatata taatccaagg cgacgttgac gcagtttgaa
    20581 gagattttcg aagagtatta aatatcgaaa cagggagtga gtcaaaggct cattccctat
    20641 ttcaacattt ttctattatg gttttacaac ttctgctgct tcaactttac cattgttcat
    20701 ggtcatcatg taagcagttt tgactgtgtt gtggtctgca tcgaagcttg tttgaccagt
    20761 tacaccttca aaatcttttg ttttagcaag gttatccttg atttcacctg aatttttagc
    20821 accttttgct gcgtttgcta caaggtgaac tgaatcataa gccaaggctg caaatgttga
    20881 aggctcttca ttgtacttag cacggtaagc gtcaaggaag gctttagctt tagctgaaac
    20941 ttctacagta gttgagaagc ctgagataaa gtagatgttt gatgcttttt cagcagttgc
    21001 ttgttgtaca aactcctcac cgttgaatcc atcaccacca acgattggtt tgtcaattcc
    21061 cataccacgc gcttggttta caatcttacc agcctcatta tagtaaccag gaacaacgat
    21121 agcatcaaag tctttccctt tcatttttgt aagggctgct tggaagtctg tgtcacctgc
    21181 tacgaaagtt tcatctgcaa cgatttcacc cttgtatgac tcgcggaaag atttggcaat
    21241 ccctttagca tagtcactgg cattgtcagt gtaaagaaca actttcttag catttaattt
    21301 ttcagaaaca tagtttgaga taatttttcc ttggaagcta tcttggaaag ttccaataaa
    21361 gaggtaatct tgacctttag tcaatccatc ttgagtcgca cttggtgaga tcaagggaac
    21421 acctgctttt gtagcgttcg ctaccgcagc tgcagtcgca ccagatgttg caggtcctac
    21481 gactgctgat actttagatt gggttacaag gttagttgta actgaagcag cctcagctgt
    21541 ttcagactta ttatctttat cgactacttc gatttgtttt ccatcgatac cacctgcggc
    21601 attgatttca tcaacagcca attgggcacc tttttgttca gctgttccgt atgcagctaa
    21661 agaacctgat tcttcaaagt taaacccgat tttaattgtc ttttcctcta ctgagttacc
    21721 agcagtgttg actgctccag acttcacttc tccacaggct gcaagaagtg ctacacttgc
    21781 aagcgccaca aacgataggg caaatttttt cttcatcttt ttgtctcctt atttcttaaa
    21841 tagtctgtta agaatatacc gaattatcag aaaattgtca atgttttcct tgaacttttt
    21901 cgatgataac gttttcctat cgataaagat tgcccacaaa gggtgtttcc aactcttgga
    21961 tatgacaaac cctaactttt ttaataaatt tttccttgct caagcgtccg accaattgct
    22021 ccacttcttg agttggaaca tagagttgta agtaacgatg tttcttggaa tgataggtaa
    22081 tatctccata atcctgcagt tttttggcat cacgattata gtaaagatag ataatcaagc
    22141 cagagcgatt gactttttca aacatgataa atcctctttc taagaaatct ctccctatta
    22201 taccaaaaaa agcaaaccca gtcgagtttg ccttctatca tcattagttc aatgaattgt
    22261 tggccataat ttcatcaata aagccatatt caagtgtttc ctgggcgctc atccagttat
    22321 cacgttctgc atctgcatgg actttttcca ttgactgacc tgaattttca gccaagattt
    22381 tttccaaggt attacgagtt ttgagcaagt gttctgcagc gatagccata tcagtttgtt
    22441 gggtaccacc acctgtaccg cccattggtt ggtgaatcat gtattcagca tttggaagca
    22501 tgaaacgttt gccttttgct ccacttgatg cgatgactgt tcccatagat gcagccattc
    22561 ccataacaat ggtttggaca tctgccttga taaagttcat ggtatctacg attgccaaac
    22621 cagctgaaac agaaccacct ggtgtattga cataaaggta aatatctttt gtactatctt
    22681 gggcatccaa gaaaagcaat tgggcaataa cagagttagc catattgtct tcaaccggac
    22741 ctgtcagcat aatgatgcgg tctttgagaa gacgtgagta aatatcgtaa gaacgttctc
    22801 cacggcttgt ttgttcaata actacaggaa tcattcattt ctccttttga gttttaattt
    22861 tgttggtcaa atgactgaag ataagactat tataatatct tggtcaaaaa aggtcaaatt
    22921 tttgctctgc tttcattaga cagaaacaaa aacccaacct cctttcgtga ctggaaatac
    22981 ttttccaagt cattcttctt ttcgatctta ttttgtaccg aacaagcggt ctccagcatc
    23041 tccaagacct ggaacgatat aaccgtgttc gttcaaacgt tcatccaagg ctgctgtaaa
    23101 gatttctaca tctggatgag cttcttgaag ggcttttaca ccctctggag cagatacaag
    23161 gcagacaaat ttgatatttg atgcgccacg ttttttaaga gaatcaacag ccaagattgc
    23221 tgagccacct gttgccaaca ttgggtctac tataaaaatt tgacgttggt caatgtcctc
    23281 aggcaatttc accaagtatt caactggttg aagtgtttct tcatcacggt acataccgat
    23341 gtggccaact ttagcagctg gaaccaagct caagagacca tcaaccatcc cgatacctgc
    23401 acgcaagatt gggacgatgg ccaatttctt acctgccaat tgtttttgaa ctgtttttgt
    23461 aattggtgtt tcgatttcca catcttctag tggaagatca cgaagtactt cataccccat
    23521 caacattgca atctcatcta ctagctcacg aaaagctttt gtagaagtat ctgtacgacg
    23581 caagattgac aatttgtgtt gaatcagtgg gtgattaata acttcaattt ttcccatttt
    23641 tggaattcct tctttcaatt tattcttctt attataccaa aaaacggttt aaaaatcttt
    23701 ctaagccatt tatttttgat aatttttaca ttagatcagc ctctttaaga gctgtctgta
    23761 ctgtctcaag tggtaaatgg gtcaattctg tccctttttc ttgataaagg tattgggcgt
    23821 agtcgtccat tcggtactgg ttgatataaa ccacgcgctt gcagccgacc tgaagcaatt
    23881 gttttgtaca gttgagacaa ggaaaatggg ttacataggc tgtaaagcct ttgggaacac
    23941 cacgctcagc accttgaagg atagcattga cctcagcgtg aagggtgcga acacagtggc
    24001 cttcaatgac caaacattcg tgatcaatac aatgctcagt ccctgacacc gaaccattgt
    24061 aaccagtgga aataacctta ttatctttta ccagaatcgc gcccacttta gcacgtttac
    24121 aagtggaacg attcgcaatt agtagggctt gggctgcaaa atactcatcc caggccagtc
    24181 ttttttcagt catctctttt ctcctttttc tctatttttt aaaaaatggt aaacctaaat
    24241 ctgcaatctt ttcagctggt accttcatgc catccttgat ccattttaga aggacagaga
    24301 cgatggctga gctccagaag gaatgaagat aagagctgac accttttgat ttcccatggt
    24361 atttttctag aaattcctgc atggcttgga caaagatttt ttccagatgg taatccaagg
    24421 ccaattgaat cactctagct tcctttctgg cctcccggaa aaggtgaacc caaaccaaat
    24481 aaaggtctgt ctttaaatcg taatgatgca gctgttccat aatattgtgg acagttcgtt
    24541 taaagacgct ctctaaaatt tcctctttgg agtcataatt gcgataaaag gccgcacgcg
    24601 aaacacctgc acgtttgacc aattcagaaa tactaatctt ggtcagctcc tttttttcca
    24661 agagttgcaa gagggctgtt tcaatggctt ctctggttaa taaattggat tcttggtttg
    24721 attttctgag attttcaaga gacttttcag agattctacg ttcagacata acattttctt
    24781 tctacttgtc acaacagacg gatgatgctt ttgtttcaag ggttttcatg atataattgt
    24841 aaaaaaagac agaacctttg tcaatgtata actgacaaag atggagaatt tctatgactt
    24901 ggaaaattat tgctgactct ggttgtgatt atcgtcaact gccaacacca gctattaaca
    24961 caacctttgt aagtgtcccc ttaaccattc aagtagctga tcaggtcttt gttgatgacg
    25021 ccagtctcga tattgaccaa atgatggaaa ccatgtatgc aactgcagaa gcttcaaaat
    25081 cggcttgtcc aagcccagat gactatttgc gagcatttga aggtgccaaa aacattttcc
    25141 tagtaaccat cacaggtacc ctttctggca gtcacaatag tgctcaacta gcaaagaata
    25201 tttatctaga agaccatcct gacactaaga ttcatgtgat tgatagttta tctgctggtg
    25261 gtgaagttga cctactcgta gaaaaattga atgacttgat tgaccagggc ttgtcttttg
    25321 aagaagtggt tgaagctatc actgcctatc aagaaaaaac taagttgctc tttgtcctag
    25381 ccaaagtcga taacttggtg aagaacggcc gtttgagcaa gcttatcggt acggtcgttg
    25441 gccttctcaa cattcgtatg gtcggaaaag ctagtgaaac tggaactctc gaattgctac
    25501 aaaaagcaag gggatcaaag aaatcagttc aagctgccta tgatgagtta gtaaaagctg
    25561 gatatgctgg tggccgtatt gtcatggccc aacgcaataa cgaaaaatgt tgtcaacagc
    25621 tctcagagcg aatccgtgaa accttcccac aagcggatat taaaattcta ccaacctctg
    25681 gtctctgcag tttctatgca gaagagggcg gtttgctgat gggctatgaa attgattaat
    25741 tgcattcttg acaagaggtg accatcatct cttgtttttt tgtggtacaa tagagctatg
    25801 aaacattttg atactattgt catcggtggg ggacctgctg gtatgatggc tacgatttcc
    25861 agtagctttt atggacagaa aaccctcctc atcgaaaaaa atcggaaact tggaaaaaaa
    25921 ttagctggga ctggtggggg acgttgcaat gtgaccaaca atggtagctt agacaacctg
    25981 ctagctggaa ttcctggaaa cggacgcttt ctttacagtg ttttctccca gttcgataat
    26041 catgacatca tcaacttttt tacagaaaat ggtgttaaac ttaaggtcga agaccacgga
    26101 cgcgtctttc cagccagtga caagtctcgg actattatcg aagctttgga aaagaaaatc
    26161 accgaactag gtggtcaagt tgctactcaa atagaaatcg tttctgttaa aaaagtagat
    26221 gaccagtttg tccttaagtc agcggatcaa accttcactt gtgagaaact cattgtcaca
    26281 acaggtggta agtcttatcc ttcgactggt tcgactggtt ttggtcacga gattgctcgc
    26341 cattttaagc ataccatcac cgatcttgag gctgctgaaa gtcctttatt aacagatttt
    26401 ccacataaag ccttacaagg gatttctctg gacgatgtga ccctaagtta tggtaagcat
    26461 gtcatcactc atgatttact ctttacccac tttggtttgt caggtcctgc tgccctacgc
    26521 atgtctagct ttgtcaaagg tggggaggtt ctctcactcg atgttttgcc tcaactttct
    26581 gagaaggact tggttacatt tctagaagaa aatcgggaaa aatccttgaa aaacgcttta
    26641 aaaaccttgt taccagaacg cttggccgaa ttttttgtac aaggatatcc tgaaaaagtc
    26701 aaacaactga ctgaaaagga acgagaacaa cttgtccagt ccattaaaga acttaaaatt
    26761 cctgtaactg gaaaaatgtc ccttgcaaag tcctttgtta ccaagggtgg agtcagtctc
    26821 aaggaaatca atcctaaaac ccttgaaagt aagctggtac ctggcctcca ctttgcaggc
    26881 gaagttatgg atatcaatgc ccacacgggt ggctttaaca tcacttctgc cctctgtacc
    26941 ggctgggtgg cgggaagtct gcattatgat taaagattaa aggttgtgaa gaatgaacag
    27001 aagagaggca gtcgaatttg ttaacatgtg tatgattaaa aacggagata aggtcctggt
    27061 ccaagaccga gttagtcccg actggtctgg cattactttt cctggtggtc atgttgaacg
    27121 tggcgaatcc tttgtcgatg ctgtcattcg tgaagtgaaa gaagaaactg gtctgatcat
    27181 ttccaaaccc caactctgtg gtatcaaaaa ctggtatgac gacaaggatt atcgttatgt
    27241 cgtccttttt tacaagacag aacactttac tggtgaactc cagtcttcag acgaagggaa
    27301 agtttggtgg gaggactttg aaaatctttc tcatctaaaa cttgcaaccg atgatatgtc
    27361 tgatatgctt cgtgtgtttc tagaagaaga tctcagtgaa ttcttttact acaaaaacgg
    27421 tgacgactgg ctttatgatt tgaagtaaaa aataggctag gaaattccta gcctattttt
    27481 tctgcatttg tctgaacgta agccgcaatg gcatctgacg tgtactgggc tgtttcagaa
    27541 ccaaacttgt caatgttttc cttaaactct gggttgtaga cgtaaccttt accgatatga
    27601 ccgaatacct caatagagca gtcaaatcca taagtgcgaa tggcttgcaa gagcttggct
    27661 gcttgctcct ggttttcggt tgctgttgca ggtaaaccaa cttgaagatt ttgtgccaaa
    27721 gtttgaaaga cttggttaaa ggcggccgta gcctcgtctt cgtgaccttt ttggcgttcg
    27781 agcgcttgtc ccatgacttc ttgaccatat ttctctaccg cttcttggtg gtatttttga
    27841 ttgtcttgat agctaaatcc cgtgaatttt tcctcaatgg tcatttttct ttctcctttt
    27901 tgttcttgaa tagttttttg caaggtggaa atcaaggtat ccagatgttg cctttcgcga
    27961 gttagatagt ccaactacct agtcaaatgg agcaataaat ctgtcctttc ttcctttaac
    28021 agttctgcta ttttctctaa agaaaagcct agatatttgt agtaaagaat gacctgaagg
    28081 cgttccaaat cctcttgact ataggttcga tagccgtttt ccgactttaa ggggaccaag
    28141 agtcctatct tgtcatagtg atgcagggcg gggtcttgac agagacacct gaaagctgcg
    28201 cagcttcttt tatatggtac atgatttcct ccttacaatg atagtataac ccctcccctt
    28261 aggtcagagt caagcgtttt tgagaaaggt gtgaaaactt gaaaatggtt ttcttgacag
    28321 accttagaaa acataatagg atagtcaagt ctatcaatca aacagaaggc tatttgacaa
    28381 ctcaagtagc tttttcttat tttgaaaaag gagatcagag tttaactatg tcagaaaaat
    28441 cacaatgggg gtcgaaactt ggctttattc tagcatctgc tggctcggtc atcgggcttg
    28501 gttccgtttg gaagtttccc tacatgactg ctgctaatgg cggtggaggc tttttactaa
    28561 tctttctcat ttccactatt ttaatcggtt tccctctcct gctggctgag tttgcccttg
    28621 gccgtagtgc tggcgtttcc gctatcaaaa cctttggaaa actgggcaag aataacaagt
    28681 acaactttat cggttggatt ggcgcctttg ccctctttat cctcttatct ttttacagtg
    28741 ttatcggagg atggattcta gtctatctag gtattgagtt tgggaaattg ttccaacttg
    28801 gtggaacggg tgattatgct cagttattta cttcaatcat ttcaaatcca gccattgccc
    28861 taggagctca agcagccttt atcttattaa atatctttat tgtatcacgt ggggttcaaa
    28921 aagggattga aagagcttcg aaagtcatga tgcccctgct ctttatcatc tttgttgtta
    28981 tcatcggtcg ctctctcagt ttgccaaatg ccatggaagg ggttctttac ttcctcaaac
    29041 cagacttttc aaaactgact agcgctggtc tcctctatgc tctgggacaa tctttctttg
    29101 ccctctcact aggggttaca gtcatgttga cctatgcttc ttacttggac aagaaaacca
    29161 atctagtcca gtcaggaatc tccatcgtag ccatgaatat ctcgatatcc atcatggcag
    29221 gtctagccat tttccaagct cggtccccct tcaatatcca gtctgaaggg ggaccgagct
    29281 tgctctttat cgtcttgcct caactctttg acaagatgcc ttttggaacc attttctacg
    29341 tcctcttcct ctttgcgact gtcacttctt ctgtcgtgat gctggagatc aatgtgggca
    29401 atatcaccaa ccaggataac agcaaacgtg ccaaatggag tgttatttta ggaattttga
    29461 cctttgtctt tggcattcct tcagccctat cttacggtgt catggcggat gttcacattt
    29521 ttggtaagac cttctttgac gctatgaact tcttggttcc caatctcctc atgccatttg
    29581 gagctctcta cctttcactt tttacaggct atatctttaa aaaggctctt gcaatggagg
    29641 aactccatct cgatgaaaga gcatggaaac aaggactgtt ccaagtctgg ctcttccttc
    29701 ttcgtttctt cgttccgtca ttccaatcat catcgtggtc ttcatcgccc aatttatgta
    29761 atcaaaaagg acttgagtaa tgaactcagg ccctttcttt tttatggatg actaacaatt
    29821 aattctaaat cttgcccttc cagagtccaa gcttcaacat cacttggtag gataaagtgt
    29881 ctcccttttt ggattggata gtttttcccg tcaacagtta gttgaccttg accagccaag
    29941 acactcaaca agctgtagtc agctgtcttt tcaaagttaa cttttccagt aatttcccat
    30001 ttgtaaactg cgaagaaatc attggataca aggagagtgg aacgtagatc atctgctttg
    30061 attgtcactg gacggctatt tgcgggttca ccaatgttca agacatcgat agatttttca
    30121 aggtgaagtt cacgtaaatt gcccttgtca tccttacggt caaagtcata gacacggtaa
    30181 gtggtatcgc tagactgctg ggtttcaaga atcaagatac ccgccccgat agcgtgcatg
    30241 gtaccgcttg gtacatagaa gaaatctcct gctttaactg gcacttttgt caacagcgca
    30301 tcccagttct tatcctcgat ttgctggcgg agttcttctt ttgacttggc attgtggccg
    30361 tagataatct ctgaaccttc atccgcagcg atgatgtacc agcattctgt ttttccaagt
    30421 tcgccttcat gctctagtcc ataagcatcg tctgggtgaa cttggacact gagccagtcg
    30481 ttggcatcga ggatcttggt caaaagcgga aatacaggtt ctggacgatt gccaaataat
    30541 tcacggtgtt ccgcatacaa agtagcaaga tctgttccct cgtaacgacc attggcaact
    30601 ttagaaacac catttagatg agctgagata gcccagtact ctccgacttt ttcacttggg
    30661 atgtcgtagc caaactcatc acgtaacttg gtaccacccc agattttttc ttgcataact
    30721 gattgtaaaa ataatggttc tgacatctta atctcctgtc tgatttttct cccctcatta
    30781 tagcaaaaaa agagttccat ttgaactctt ttttacatct tataaagcag ggagaagatt
    30841 ttataaaaat agtaaacaaa tgtgctctac tcgatgctta caccattgct ataaatgaca
    30901 tgtaccaata gaaggacttc ttcttgctac gtttgagagt cccatttcct acattatctc
    30961 gatctacata gataaagcca tagcgcttat tcatttcccc tgtgccagct gaaaccggat
    31021 cgatacagct ccaagtcgta taaccaagca agtcaacccc atcttggtaa atggcatctc
    31081 gcatggcctt gatgtgggcc tctaagtaag taatccgata gtcatctgct acataaccat
    31141 tctcatccgg tgtatccata gcaccgagtc cattttctac gataatacta aactaaaatc
    31201 aaaaagcatt atacaatagt aatatgaaat caactaaaga agaaatccaa accatcaaaa
    31261 cacttttaaa agactctcgt acagctaaat attataaacg ccttcaaatc gttctatagt
    31321 aaaatgaaac aagaacagga caaatcgatt tctaacaatg ttttagaagt agaggtgtac
    31381 tattctagtt tcaatctatt atatttcgtc tgatgggcaa atcttataaa gagattatag
    31441 agcttttaga ctgtaatcaa acaacgattt agcaaaatgt aaaaaatatg aggagttcgg
    31501 actcgactct ctccttcaag aaacacgtgg tggtcgtaac catgcatata tgacagttga
    31561 ggaagagaaa gcctttcttg cccgtcattt gaaggctaca gaggcaggag aatttgttac
    31621 aattgatgcc ttatttcagg cttataaaaa ggagttaggt cgttcctaca cacgtgatgc
    31681 cttctatcaa ctgttgaagc gccatggttg gcgaaatatt acgccacgtc cagaacatcc
    31741 taagaaagca gacgctcaaa ccattgtcgc gtctaaaaat aaaatctcaa ttcaagaaga
    31801 caagaaagcg ctttaaaacc agtagacctt ttcataaggt tcgcttgatg tcccaagatg
    31861 aggctggttt cggtagaatc agtaaactgg gatcttgttg ggctccaata ggagtaggtc
    31921 cacatgtcca tagtcactat atacgagaat ttcgctattg ttatggagct gttgatgccc
    31981 atacaggcga atcatttttc ttaagagctg gtagatgtaa tactgagtgg atgaacgcct
    32041 ttttagaaga gctttcacaa gcttatccag atgattattt tttactcgtt atggacaatg
    32101 ctatatggca taaatcaagt accttaaaga ttccgactaa tattggcttt gcatttattc
    32161 ctccatacac accagagatg aagcccattg aacaagtgtg gaaagagatt cgtaaacgtg
    32221 gatttaagaa taaagccttt caaactttgg aagatgtcat gaatcaactc caagatatta
    32281 tacaaggact ggagaaggag gtgataaagt ccatcgttaa tcggagatgg actagaatgc
    32341 tttttgaaag cagatgagta ttatatgcaa tttctttata taaaaagacc ggattgctcc
    32401 gatctttcaa tagttcatat tctcaatttc tattttaaaa atagctaagg ttaacgtcaa
    32461 atgactacgc gacctatttc atacgataaa aatcaagcac tagaccagca ggtccttgaa
    32521 ctaataagga ctctgttccc caatcggtta cagttggtcc gtgtaaaacc tttataccaa
    32581 gctcgttcaa ccgtttgtag ttctggtcta catcctcaac ctcgatatga ataatgattc
    32641 ctgactgaaa gttttccaaa ggaaccaaat gattttgtga caacataagg cagtgactac
    32701 caatcgtaaa ctgagcaaaa ccatcatcag cataatctgc ctttttatcc aagatatgct
    32761 ccaagtcagc acagacttgg ggaacatttg aaacgataat atctaattga tttaaattca
    32821 tttactctcc tccataaaaa gaccggattg ctccgatctt ttaaagttct gctctatgaa
    32881 aatcaaagaa taaagtctac aagtttcata tttgattttc ggcgagagga attatttaat
    32941 tgcgcgtgat tgcaatcctt cttcttccaa gaagagacgg aatggtacga gttcttctgc
    33001 ttcgtatttt tccttgaagg ctttgatagc ttcttctgag tgaagttttg gatccaattc
    33061 aagtacttct actggaagtg gacggtgttg agtgatgcga gcatcgatga caacagtttt
    33121 accttctttg ttcaatttaa cagcttctgc aacaactgca tcgatgtctt cgatacggtc
    33181 aactgtgaat ccaacagctc cttgagcttc cgcaatttta gcgtagtcag cgtttgtgaa
    33241 gtctacacca aacaagtgtt tgtttgtatc ttcgtatttg ttcttgatga agccgtactc
    33301 agcatttgag aagacaaggt tgataactgg aaggtcgtat tgaacgtttg tgataacgtc
    33361 tgggtagcac atgttgaatg ctccgtcacc catgatgttc catacttggc gatctggatt
    33421 gtctttctta gcagcgatac caccaggaag ggcaataccc attgtcgcaa agagtggaga
    33481 tgtacgccac atgttcttag gtgtcatgtg aaggtgacga gtagatgttt gagtagtgtt
    33541 acctacgtcg attgagtaga tagcgtcttg atcagcatgt ttgttgattg cattgtaaac
    33601 ttgatacaat tgcaattcac cctcagtttt accttcgagt ttgttcatgt aatcacgcca
    33661 gttttggttg ttcttaacgt ttgcacgcca ccatggagtt gattcaactg ggtttacttt
    33721 gtcaaggata gctttagctg cttgaccagc atcaccaagg attgaagcgt caagggcatg
    33781 acgtttacca agtttgtaag ggtcgatatc gacttggatg aatttttcag tgttcttgaa
    33841 tgcttcgtaa acttcagcaa atgggaagtt tgaaccaagg aaaagaactg tgtctgcttc
    33901 aaagaccact tcgttggctg gtttccaacc aacacggtaa gcagaacctg tcaaaccttc
    33961 atagttccat tcgaaagctt caaagttttt accagttgtg atgattggtg ctttgatttt
    34021 acgtgacaat tcagtaatca cttcaccagc tttaacacca ccaaatccag catagataac
    34081 tgggcgttca gcattgttca agatttcaac agctttgtcg atttcaactt cgttcaaagc
    34141 aggagcgatg aatgagcgtt cgtatgaacc tgaaccgtag tatgagtttt catcgatttc
    34201 ttggaaaccg aagtttactg gaatttcaac aacagctgga ccttttttag aaactgcagc
    34261 acggcaggct tcgtcaatta cttttggcaa ttgctcagcg taagctacac gtttgttgta
    34321 aacagcgata ccgttgtaca ttgggttttg attaagctct tggaaagcat ccatgttcaa
    34381 ttcgttaact ggacgtgatc caaggatcgc taggaatgga gtgttatcca tagctgcatc
    34441 gtaaacaccg ttaatcaaat gagtcgcacc tggaccacct gaaccaactg caaccccgat
    34501 tgagccgccg aatttagctt gcataaccgc tgcaagagca cctgtctctt cgtggcgaac
    34561 ttgtaagaag cggatatctt tgtcttcagc caaagcgtcc atcaatgagc tgagtgttcc
    34621 tgatgggata ccgtagattg tatctacgcc ccatgttttc aatacgttaa gcattgctgc
    34681 agatgcagta attttccctt gagtcataat gataactctc cttcaatttt tttagacttg
    34741 gagaatacga ttacatagaa ttggaaacgt tctccaaatt tttactattc cactgtatca
    34801 tatttatgct gacttttcta aaaatctgct caaaactctc tattctctat tctaatacag
    34861 ttttgaaagt gtcgtcattt ctgttttata acaaaaaaat ctagtcatta cttttagtct
    34921 attttactaa aatttaacag aagggaactg gtcagaacag atacagaact aaaggccatg
    34981 gctagacctg ccaattctgg gttgagagcc agtccaacac ctgaaaagac tcctgctgca
    35041 atcggaattc cgacaacatt gtagataaaa gcccagaaaa gattgagcag aatacgatga
    35101 aaggttttct tactcatgtc gaaggcacgc accactccta aaagattatt ggttgtcaac
    35161 accaaatctg ctgactcgat ggcgatatct gttccagctc ccatagcaat ccccacatct
    35221 gctacactaa gggcaggagc gtcattgatc ccatcaccaa caaaggctac tttacctgac
    35281 tgttgcagtt tatggatttc atgggctttt tcttctggca agacgcctgc aatgacctct
    35341 tcaattccga tttgatctgc aatagcacgc gccacaccag cattgtctcc tgtcagcatg
    35401 actgtcccga gaccacgttt ttttagctga ctgatggcta gcttagcatt tttcttagga
    35461 atatcttgca aagcaagcaa gcctttgatt tcattgtcaa cagctaagaa cacaactgtc
    35521 ttagcttctt tttctagttc ttctagttta tcttgataag tattagaaat atccatgcca
    35581 tccagcattt tagcatttcc aagtaaaact tgttttccat tgattcgccc tgaaacacct
    35641 ttcccgtgca aggcctgaaa attttcaaca gtttgaaact caagtccagc ttcactcgct
    35701 cgcttaacga tagcctcagc cagtgggtgt tgagaagcat cttccaagga ggctgccaat
    35761 ccaaacactt ctacttcgtc gccgatgaca tctgttacca caggtttccc ttccgtcaaa
    35821 gtcccggtct tatcaaagac aagggtttga actttctgga tttcctgtaa gacagttcca
    35881 tttttgagga gaacccccat cttggcacta cgtcctgtcc ccaccataag ggctgtcggt
    35941 gttgcaagtc ccaaggcaca aggacaggcg ataatcaaaa ccgccactcc gtagagaaga
    36001 gaggacacaa agctagctcc aagcacaacc acactatccc tgagcaagac gaaccaaacc
    36061 caaaaggtca tgattcctaa aatgacaact actgggacaa aaatccctga aatcttatcc
    36121 gtcaagtcct gaatcggcgc acgacttgtc tgagctttct tcacaaaatc cacaatctga
    36181 gccaaaacag tctctgagcc aactttttct gctctaaaga caagcgttcc actatgattg
    36241 atggttgagc caatgacagt atctccaact gtcttgtcca caggcagact ctcacctgtc
    36301 accatggatt cgtcaatact agagacacct tctactacga caccatcaac agcaatcttt
    36361 tcaccgggac gcactcgaat caggtcgcct accttgactt gttccaaagg aacttggaca
    36421 taactatcat cactcaagac ttctgcggtt ttagcttgca agtccagtaa tttctccaca
    36481 gcttgggacg tattttttct cattttttcc tcaaaaactg ctcccaaaag aacgaaaaag
    36541 aggataaatc cagcactttc gaagtaaaca gggagaccag caaagagagc aactaggcta
    36601 tagaaataag ccactagagt tcccagcgca accaaggtat ccatgttggc attgtgcttt
    36661 ttaaaactgg cccaagcact ctggatatat ggcttacctg caactaacat aataggcgtt
    36721 gttgctagaa aggttcccca atgcatgact tgatgactaa tgctacctgc caacatccca
    36781 atcatgagaa tcacaagagg cacagtacag atactagtaa tccaaaaacg ttgcaggaga
    36841 gatagagatt ttcgagtctt ctcaacgact gtatagcttc ccttttgcat cttcatgcca
    36901 caagaaaatt catgtcgccc taattcttga ggtgtaaaac gaatgacttt ctcctcatct
    36961 acgccgattg gttccaagat accttcttct tcaaacagaa tttccttata acagtttgaa
    37021 ggagtagcac gatgaaaggt aatctcagct ggaattccct tttgaagctg gatatgggct
    37081 ggatgatagc ctttttcagc ttggatacgg attttttgaa tgccattttc taagcttgct
    37141 ttcacaattt ctgtcatagt ctccacctac tctacaatca tcttgccgtg catcatgttc
    37201 ataccacaag caaagctaaa ctctccagcc tgttcaggcg tgatttccac tacatactct
    37261 tcccccattg gcaggttcgc atgtacacca aaatctggaa aaacaatttg atccagacat
    37321 ggtgaaggat ccttgcggtc aaagacaatg cgggctggca ctgatttctt gaggacaatc
    37381 aactcaggag tatagcctcc catgacttcc actcgaatct cttggtatcc gtttttttgc
    37441 tgggcttttt gtccagattt ttcaggcttt ttgaaaaacc aaaacaagat aaacgcgata
    37501 agggcaatac aaataatggt tacaatacta tttaacatga cgtctccttt acatacaatt
    37561 acatcttact tctgttacag cacttgattt cttctctgaa atcacagctt ccaagtcttc
    37621 caagtcagtc tgagtaaatt cacattctac aatcaagtca gccaacaaat tcctaatcct
    37681 acgggaacaa accttgtctt tgatatcttg gacaagtaaa tcccgacttt ggtctagagt
    37741 taaaagcgct gaataaacaa aggacttgcc ttcttttttc cgagtcaaac actctttctc
    37801 aactagacga gccaaaagtg tctgaaccgt ggacttggac cagtcaaacc gctctgccaa
    37861 aaccctaatc aaatctgtac tggtctgctc cccctgcatc caaataatct tcatgacctg
    37921 ccattctgca tctgaaatct gcattaccat acctccaaaa tctacatttg tcaattacac
    37981 tcaacagtat actcccaaaa tctacatttg tcaattatag aaataatatt ttcttcgaaa
    38041 aatagaattt taatcatttg aaaaacgatt tgcagtcaaa tattactata taaacaataa
    38101 aaatatgcta tactaaagaa aaaagaaaac aaccactagg ggtgcgtaaa gctgagatta
    38161 acgactgtta gatccctctg actcaatcta ggtaatgcta gctgatggaa gtggaaatga
    38221 taatggggac tagcagtctt ctattgcctt tctaaaacag actagcttgt tcttaagaat
    38281 acaaacttca gttggttggg aggttttaga tgacttattt acccgttgct ttgaccattg
    38341 cagggactga ccctagtggt ggtgctggca ttatggcaga tttaaagtca ttccaagcga
    38401 gagatgtcta tggaatggct gttgtaacca gtcttgtcgc tcaaaatacc agaggtgttc
    38461 agctaatcga gcacgtttct cctcaaatgt tgaaagccca attggagagt gtcttttctg
    38521 atattccacc tcaggctgta aaaactggaa tgttggctac tactgaaatc atggaaatca
    38581 tccaacccta tcttaaaaaa ctggattgtc cctatgtcct tgatcctgtt atggttgcta
    38641 caagtggaga tgccttgatt gactcaagtg ctagagacta tctcaaaaca aacttactac
    38701 ctctagcaac tattattacg ccaaatcttc ctgaagcaga agagattgtt ggtttttcaa
    38761 tccatgaccc cgaagacatg cagcgtgctg gtcgcctgat tttaaaagaa tttggtcctc
    38821 agtctgtggt tatcaaaggc ggacatctca aaggtggtgc taaagatttc ctctttacca
    38881 agaatgaaca atttgtctgg gaaagcccac gaattcaaac ctgtcacacc catggtactg
    38941 gatgtacctt tgctgcagtg attactgctg aactagccaa gggcaagagt ctttaccagg
    39001 cagttgataa ggccaaggcc tttatcacaa aagctattca agatgcccct caactcggtc
    39061 atggttctgg tccagtcaac catacaactt ttaaagatta agaaaaaaaa ctctctagtt
    39121 cccactttaa gggaattaga gagtttttat actcttcgaa aatctcttca aactacgtca
    39181 gcttccatct gcaacttcaa aacactgttt tgagctgact tcgtcagtct tatctaaaac
    39241 ctcaaggcag tactttgagc aacctgcgac tagctttcta gtttactctt tgattttcat
    39301 tgagtattaa ttaggaaaga atgtcatgca actttgttaa aaaggcttgc gtttttgcct
    39361 caatatcttc tgcttgcatc aaatcacgta caacagctac accagctatg ccagtgccca
    39421 taagctgatc aatattctcc gaagtcaagc caccaatagc aactattgga atggcaaccg
    39481 tttggcaaat tgttttcaag gttgaaatca gggtgatggg tgcattttcc ttggtggttg
    39541 tcggaaaaat ggctcctgtc cccaagtaat ctgcacctga tttctccgct tccagagctc
    39601 ttttaaccgt tttagcggtg acaccgagga ttttttcagg acccaagact tgtcgggcaa
    39661 ccgaaactgg gagttcgtca tctccaatat gcagaccagc agcatcaacc gcaagacaaa
    39721 catccaaccg atcatcgatt atcaagggta cctgataagc atctgttatt tccttgactt
    39781 gttttgccag ttgataatat tgattggttg tgagattttt ttctcgcaat tggactatgg
    39841 taacccctga acggcaggcc gtctcaactt ttgcaagaaa gctttccacg gaatcttgat
    39901 agcgattggt taccagatat agtctaagtg cttctctatt cataaacctc tcctttgatg
    39961 gtatctagcc aattttcatc tcttcttagg agcgaaagct gattgagtac ttggtaacga
    40021 aattcttcca atcccattcc ttgaacaact attttctcag cagcgatatt gagataagag
    40081 actgctaagc aagaagcttc aaaaccagtc tttccttggc tgagaaaaac ggctgttaag
    40141 gctccaacca aatctcctgt ccctgttatc cagtctaatt ctgcacagcc atttcccagt
    40201 acagcgacct gatttttcga aacgacgagg tccttgggac ctgtgactaa gaaagacata
    40261 ccatgatagg tctgacacca gtctttcaag acttgaagca aatcctccgt ttcttgatct
    40321 ttagcactcg catcgacccc aacgccgtgg tgctttaatc caacaagact tcgaatttct
    40381 gacatgtttc ctttaaggac cgtaggtcta tagtctaaaa ggtctctgac taagctctta
    40441 cgaatggatg aagctgttac gccaaccgca tctactacca ttgggagaca aacttgagct
    40501 gcataagaag ctgctatacg gattgctttc tccttctcag ctgacaaatg ccccaaattg
    40561 atgaagagag cctgactttg cttagtaaaa tcaagaacct cacggggatc atctgccatg
    40621 acaggtttgc atcccagagc caaaatccca tttgccagca tctcacaaga aatctcattg
    40681 gtcatacagt gaatgaggga actagagcct ataggaaagg gatttgtaaa ttcctgcatc
    40741 agtctatcct ttcactaaag aaatatccct gcactttttt aaagaattcc tgcttgatta
    40801 aaaatcgaaa ggcaataaag gaaatcgctg taccaatcaa ggttgctccg aaaaatcgag
    40861 gcgtgtagat aaaccagcta agcttagtag ctgatcctgt aaagagtacc ataacaggat
    40921 aggaaacaat agaaccaata atacctgttc ccacaatttc tcccaaggca gaaaagtaaa
    40981 attttcgacc gtacttataa aagagacctg ctagaagggc tccaaaagtc gctcctgtga
    41041 gagctaaagg cggaatccct tgagtcgtca tacggataaa ggctgtcact gtagccatag
    41101 ccaaggcata aacaggtccc atcatgattc ccgctagaat attgactaca ctggacatcg
    41161 gtgccattcc ctcaatccga aagataggtg taaggactac atcaagggca atcatcatag
    41221 ataaaatggt caatttgtga acttgtagtt ggtgctttct catgtttcta ttcttctcct
    41281 ttttctaaag actgtaaatc gctcttccat gtctggtgtt ggtaagccat ctcccaaaac
    41341 ttggcttcca tatgaacact gatgtggaag gcatctagca ttttttgctt atctgtctca
    41401 tcactttctc gatagagctg attgaccagt gctccctcct ctctgatctg ttgctctaac
    41461 tcatccgtaa tataagtttc aatccattgt tgatagagag gatttggtga tggtttaaga
    41521 ttaagtgatt tgcctatatc atggtataac caaggacaag gaagcaagct tgcaaaagcg
    41581 atggctaagt tcggttctgc aaattgccta taaatatgag aaatgtaatg ataacaggtt
    41641 ggagcgattg gatgttgctc catttcctgg tcgctgattt ccaattcctt gaaaaattgt
    41701 tggcgaataa ataactcacc ctccactaaa ccctgagcat tttgtttcaa gagtcttttc
    41761 atctcttggt ttgaagtctt atcagccaaa agatgataga tttctgagaa agccttcaga
    41821 tagtaggcat cctgaatcag gtaatagcgg aaaatggcag gttctaaatt cccctcttgt
    41881 aattgtaaaa taaagggatg atgaaaggaa gcctgccaag ctttcttgga taattccatc
    41941 gcaatatctg taaattccat aataactcct ttataaaaat agactggttt gaagcaataa
    42001 aaagaaaagc aggtagatta attttgtttt tttaggaata taaaaagtcc gatagctatt
    42061 cttcaactgt gcatgttcgt catatccgtg agcagataga gctctcaggt aaagatggcg
    42121 ccacctaaag actgtcatca gaaccttact gtaaatcaag ggcgaccaaa aatgtagttc
    42181 ttgaccacgt aataggcaag cttctttgag ggacttgatt tcttgctgaa tgagaggaaa
    42241 ggaattgaat accacaatca aggcatagga ccaagagcgt gatagcccct tttgagccaa
    42301 gtacaagaga agctctttta gtgaaataga ggaaacaaag acaaggccga tacaaactgt
    42361 cacaaaggcc ctcgttccaa gcatgactgc ctgtgaagca tctccgtgta actgaactgc
    42421 ccagtagttg gcaaaagatg gtaaaatggc aagtatgatc atccaagcta acattttaaa
    42481 tcgacggtaa tagagcataa agagaataca aaatgcgact accgaaagat tcagagcaat
    42541 cgaaggaatg aaagatgttt ccaaggataa aatcagcaag aagagactga taatcggtgt
    42601 ctgggttgct actttgacca tactatctca cctccccttg ggtattgcta ctctgagatg
    42661 taagtggttt ggtaatggtc acttctttca catgccgaag accctgacta gtcatctcaa
    42721 tccaataatc aaccacagaa atcaaagggt ctaaacgatg actaatgagc agaaaacttc
    42781 ttccttgatt cctctcctcc acaatccact tgcaaaaata atggcaggct ctatcatcca
    42841 aacctgcaaa aggttcatct agcaagatca cggaagcctt actggtcaag atggtcaaga
    42901 gctgaagaat tttttgctga ccaccactta attgataggg actcttatcg actgcctgct
    42961 ccaaatcaaa atatcgtaaa gcttgaaaaa tccgctgatt tctttcagaa tcaggtccat
    43021 ctaattgaag ctcctctcgc agactgactc ggataaactg cttctcagct tcctgaacaa
    43081 tacccgtcag atcacggtac aaactctttt tctttttcag gactgtcccc ttccatgcaa
    43141 tgcgcccctt atacttttga aattgaagaa tagaccgaaa gagggttgat ttcccgacac
    43201 cattgtcacc caggatacag gaaatccctt gatagaatgt gaaatcagca attgaaaaga
    43261 gggggcgatt accaagctca ccagtcacac ggttcatatg gaataattcc gggctagaag
    43321 caacttcctt tgaagcaacc tgtgtcatct cataggaagg gatttgaaac acttccctta
    43381 gttttccgtc tcttagctca accatatggt cgatataggc tttatagtca gataaatcat
    43441 ggtcgcacaa aataactgtc ttcccatcaa gagccaactc ttttagaatc tccaatatct
    43501 cgattctgct cttgcggtca atggaagcga agggctcatc caagagatag accctaggat
    43561 tcatggcaaa gaggacagcc agcgctgctt tttgcttttc cccacctgat aggtgatgaa
    43621 tgggacggtg taagattgcc tcgcaacgac attgctggac aacctctgct attttagaat
    43681 caatttcctg aaggtgatag ccgatattct ccaaggtgaa aatcagctcc tcaaacaagt
    43741 tctccatggt aaattgatga ttgggatttt gaaagagaat gccaaccttc tggacacgtt
    43801 cgacgataga aagctgactg acctcactcc catctatcag gacttgaccg ctatagggaa
    43861 gagaactgac ttgggcaatc atttgaaaga ggctggattt tcctgaacca ctgctcccaa
    43921 ctaacaaggt aaaggcttgc gcatgaaaag taaaatcaaa cggctcagag aaaattgggg
    43981 actgaatcgc tcgtagttcc agacccatct atgcttttcc tccagttgca aactgatgat
    44041 agagtttgac aatggcacga accaagatgg tacagaagaa ataaacagaa ataaaacgta
    44101 ccacaagcaa ggaaaggaca aacggaaggg aaaaggcgta gtaacctaac ttaatgtatt
    44161 catagacaaa gctaacaagc gtaatcccaa tactattagc agttagagag agccaacttt
    44221 catagcgatt cttagttacg ataaaaccaa attcacttcc caaaccttga accaagccag
    44281 acaaaagagc tcctagacca aattggctac cataaaggac ttcagcaagc gcagctagca
    44341 cttctccaat cgttgcactt ccgactctcg gaacaaagat ggcagcaatg ggcgcagcca
    44401 tacaccagag accgaagagg atttcattgg caaaggcctg caaaccaaga ggtgttaaga
    44461 gtagactgag aatattatac acatatcctg aaccaacgaa aaccccacca aaaaagatag
    44521 acaagaaagc aagcaagata acatctttta actgccattt tttcaacata aaaaaactcc
    44581 tttttttaaa gaaaagtggg gcactcaaga agaccgacct aaatactttg tatagcagac
    44641 tgaatttaga acagtacaca agaacactaa aatatttcta gaaattaatt tgaattttct
    44701 aattgatttg ttcgcatctt atttcaatct actatatcat cttcatccag tttcgtaaaa
    44761 gaaaaaactc taattacaga tacgaattag agttcagctt acaagattag acagttcttt
    44821 tcgacatacg aaaaaaacat ttcacatttc ccttcgccag tcttaactgt atcaggttca
    44881 atgggtatca tctcagccta aagcacccca aatgtcttta ttatttaatt atgtgattat
    44941 tataacacac attttatact agttcaagaa attgaactgg aaatacagcc ttgcactcac
    45001 aaagacagca gatctttctt ttgcaaaaaa caaatgacct gtttgatgaa ttagccattc
    45061 aagctgaatc tggacatagc tttttaaaaa aggaaaatcc tacttactta gaatccaagg
    45121 atagatatct attgttcact catttcccga acagtttttt ctatattttt tgcatacgat
    45181 attgccgaaa tgattgaaac gccatccata ttggtcttta taatgtcttt aatatgtttc
    45241 gtctgtatcc caccaattgc aactaaaggc atttgtggca atagttttct catcaattca
    45301 agaccttcat aacctatagc accaccagca tcatcttttg actgggtatc aaatacaggc
    45361 ccaacaccta cataatctac atattcaact tttgattgtt gaaattcttc ttcgtttctt
    45421 atagaaagac caattatttt atctggcatc aattttctaa tttcatcaac accaatatca
    45481 tcttgaccta catgtacgcc atcggcgtca atttccattg ctaaatctat atcgtcatta
    45541 acgataaatg gaacattgta ttttttacaa agttctttaa tttggatagc tagctcaagt
    45601 ttttctaagc cttctaaagc accctcacct ttttctcgaa attgaaataa ggttatacca
    45661 ccttttaagg cttcctcaac gactgtatat agattttttc cttggcaagt agtcgttcca
    45721 caaataaaat atagttttag taattcttta tgaaacatct tacttcactc ttttgaattc
    45781 ctttacatct tcatctgtaa tctcgtataa ggcatttata aattcaactt taaatgtccc
    45841 aggaagatgt ccatttggac gtttttctgc catttctcca gcgatattgt aaactaacat
    45901 tgctgtttct aatgatttta attcttgacc tttttccagt ccgataaaac ttgctactac
    45961 agctcctaat aagcatcctg tcccaatgac tttcggcatc atagcactac cattatgaat
    46021 cgttaccact tctccattaa cagcaatggc atccacttca cctgttacta ctattggaat
    46081 attgaacttc tcatttgctg ctagagcaat ttcgtcaata ttatctacgc ccgcactatc
    46141 tactccttta gatgccacat ctattcctac taaagaggca atctctccag cattccccct
    46201 aatcgcagct agtttgtaat tgttgattaa atcatctgct actttttttc tatattctcc
    46261 tgctccacag gctacaggat ctaaaactac tgggacatta tatttctctg caattttcag
    46321 agcagcttgg tataatttcc aattttcatc tgtcaatgtt cctatgttta ttaataaacc
    46381 accagcatac tttaacaaat cctctaaatc tgctggaaac tcactcatgg ctggtgaggc
    46441 gcccagtgct actaatccat ttgctgtgaa attttttact acatcattgg ttatacaaat
    46501 gaccaatggt gctttttctt ttaataattt taaacttgtc atattgaaat ccttcctttt
    46561 cactttatac gatctactaa tttcgattta tctttagttg agaatttttt tcatttacat
    46621 tgaatgattt atactcaatg aaaatcaaag agcaaactag gaggctaacc gcaggttgct
    46681 caaaacactg ctttgagcct gtagataaga ctgacgaagt cagctcaaaa cactgttttg
    46741 aggttgtgga tagaactgac gtggtttgaa gagattttcg aagagtctta cctcatcaaa
    46801 tttgtaaata tcatgagcct tctctagaca tcgtaaccaa tatcaaaaaa agctaattct
    46861 aaagcgactg cttgattcca gcgttgctga agttctgtca aatcttctcg atttttaccg
    46921 acacgattga gttcatcaac cagaaattga acccactctg caaagaaagg acctctgtgg
    46981 agattgatcc attccgaatg aatatagact tcaggtagag ccaaatcttt agaaccccag
    47041 tctaaataga gaccttctgc aatgaccagc ataaccaaaa gatgggcata gtctgatgaa
    47101 gccactgccc aatacattag atcctgaaag gcttttgtta cagggtgcaa agtcacttct
    47161 agatagtcat tctctgctac ttttaactct ttaaaagcct tttggaaata accatcttca
    47221 tctgcttcaa gaaagcctag ttgcttggca aaacgaagct tggattcaag tttatctgcg
    47281 tgagctacgc aggcacccag catggataag aaggcatcaa agaagtgata atcttgaatc
    47341 agatagtcct ttaagacctt attctcaatt gtccccgcaa aaagttcctt aacaaaacga
    47401 tgattgattg cagcctgcca atccttctga ctgcttttta ataattctcc aacagtcaaa
    47461 cctggctgaa atgcatagtc ttgtgtttcc atatttactt ctcctctctt tacttgttag
    47521 taattaataa aacaccaaga aatatcaagc aaaatcgtaa ttccacttga tccttttaaa
    47581 gcacatcgag agcatttgca gagagctaac taaacaagcc tatccagttt atataaacaa
    47641 aaaactccaa ttacaatcaa gaattagagt tgacttacaa gattagaccg ttcatttcgc
    47701 catacgaaaa aacgtttcac atttcccttc gccagtctta actgtatcag gttcaatggg
    47761 tattatctca gcctaaagca ccccaaatgt ctctattatt taattactga accagtatag
    47821 caaaaaatga aagccctagc aagatatttg accgaaaaat atctttatat agtagattga
    47881 aactagaata gtacacctct acttctaaaa cattgttaga aatcgatttg actgtcctga
    47941 ttgatttgtc ctattcttat ttcattttac tatagttttc gatagcaatt tattcttcca
    48001 atacacgaag aaaaacctcc acattcagtg gaggcaatct gttttatcaa tacaatttta
    48061 agtcacgagg gtcaactggg aaggttgggt tgtatggatt gtgacggagc ttgaagtgtt
    48121 tgacatcttc aatggtctga gctccagaca attgcataac tgtcttcaat tccgcattca
    48181 agtgttcaaa gacttgacgc acaccgacac taccaccgag agccaaacca tagatgacag
    48241 ggcgtccaat agcaaccaag tctgctcctg atgccaaggc tttaaagacg tgttgaccac
    48301 gacgaacacc agagtcaaag acaatcggca cacgtctatc aactgcttct gccacttctt
    48361 gaagcgagtc aaaggcagct ggtccaccgt cgatttgacg accaccgtgg ttggttaccc
    48421 agataccaga agctcctgca gcaagcgaac gttcaacgtc ctcacggcat tgtggtccct
    48481 tgacatacac aggaagacca gagtattcag cgataaattc tacatcgcgt ggagacaagc
    48541 gttgtttagc tgatttgtaa acaaagtcca ttgatttacc agcaccttct ggcaggtatt
    48601 cttcaacaat cggcatgcca actgggaaga caaaaccatt acgcttatcc acttcacgat
    48661 tcccccctac agtagcatct gccgtcaaga caatcgcttt ataaccttca gccttcacac
    48721 ggtccatgat gtggcggttg ataccgtcat ccttactaaa gtaaaattga aaccaatgag
    48781 gtgtcccttg aagggcttca gaaatctctg gaaggtcaac agtagagtaa gaactggttg
    48841 tataaagaga accaaactca tgcacaccac gcgcagtcgc cacttccccc tgttcatttg
    48901 ccaatttatg agccgcaaca ggcgccataa tgattggtga agatagtttt tcacctgcaa
    48961 attcaatctc tgtacttgga ttttcaacat cgcaaagtgt atgaggaacg atgagtttgt
    49021 ggttaaaggc gcggatattc tctcttaaag tgaaagtatc ttccgcccca ctagcgatat
    49081 agccaaatgc tgctttagga ataacttgtt gcgccattgg ctccaaatca taggtattga
    49141 tgaagtctac atgaccttct gcattgcttg ttttgtatga cataaaatgc cctccttgat
    49201 taagtaagcg tttgcttttt actacacaac tataataact cttttttcaa tcattttcaa
    49261 gagttttgct taaaaaccat cttatttttt catacaatat actagcccta ctttccttaa
    49321 actctaaact ttagtctata ttaagtgaat cgttgagatt ttttgctgcc aggcatttga
    49381 actacttttt tatttgctga ttctatctac taatactata aaaaagcaag tgaataagac
    49441 accagaacat cctctaatag gacctatgga cttatatcag tcccatatat actgtttaag
    49501 caagatacta tcctagttga cgctaacttc ctatcccact tattaatttt ttatttatag
    49561 tgaatctgaa caaatcaatt ggggaatcca agtcaatttc tagtactttt tgaacagttt
    49621 cagcgtacta tcgtaaaatg aaataaaaca tgcacaaatt gattagggaa tttaaaccaa
    49681 tttctaacaa tgtcttagaa atcaaagtgt actatttcaa cttcaatata ctacacttca
    49741 ttttctcctt aaattcagtc tctttttgaa tcaaaaaatc ctctggtaag agccagagga
    49801 taagaattta tttcattgtt gggaagagca atacatcacg gatagttgtt gtatcagtga
    49861 ggagcatgca gagacggtcg ataccgattc ccaaaccacc tgttggtggc ataccgtatt
    49921 caagagcctc gatgtagtca tagtcgatgc ctgtcgcttc atcatcacca agttctttag
    49981 ctttagcttg ggcttcaaaa cggctaagtt ggtcgattgg gtcgttcaac tcagtaaagg
    50041 cattaccgta ctccttagtc atgataaaga gctcgaaacg gtcagtaaag cgttgatctt
    50101 caggattttt cttagcgagt ggagatacag ctactggatg tccatagaca aaggttggtt
    50161 ggattaaagt ttcttcaaca aactcttcaa agaaggcatt gatgatgtga ccaacctcag
    50221 tgtagtgttt ctcaactgga actttcttct cagcagcgat agctttagct tcttctaaag
    50281 tcatgtcttg ccagaaatcg acaccagtaa tttctctgat agcatccacc atatgaacac
    50341 gcttaaatgg ttcgttaatc ttgatttcag taccttggta gttgactggg ccatcgccct
    50401 taactgattt agcagcgtgt tggataatgc cttccgtcaa gtccatgatg tcttggaagt
    50461 ctgcataagc ttggtaaact tcgatagaag taaactcagg gttatgagta gcgtccattc
    50521 cttcgttacg gaagatacgg ccaatttcat agacacgttc cataccaccc acgataaggc
    50581 gttttaagtg aagctcagtc gcgatacgaa gcaccatgtc aatgttttgg gcattgtggt
    50641 gggtgataaa tggacgggca gcagcaccac cggcttcatt atgaagaaca ggtgtttcca
    50701 cttcaaggaa tcctttttgg tcaaggtaac gacggatttc agagatgatt tttgaacgag
    50761 tgacaaagcg ttcaaagctt tcacggttag aaatcaagtc aaggtaacgt ttacggtaaa
    50821 ttgtttcaac gtctgtcaaa ccatggaatt tctcaggaag aggacgaaga gccttagaca
    50881 agtgtgtgat gtgggttgcc ttgatagaga gttctcccat atccgtacgc atcacttcac
    50941 cttcgacacc aaggaagtca ccaaggtctg cttttttgaa gatttcgtag ttttcttcac
    51001 cgacagcatc cttacgaacg tagatctgaa tctggccttc gcggtcttga aggtgggcaa
    51061 aaccaacttt tcctttacca cgtttggtta ccaagcgtcc tgcgatagta gctgtttcgt
    51121 ttttatcgtg taattgttct ttatcgaggt tggtatattt atcttttaat tcttgtgaat
    51181 ttgcagtacg ttcaaaacgt tttccgaaag gatcgattcc ttgttcgcgg agcgcagcca
    51241 ttttttcacg gcgaacgatc tgctggtcat ttagttcttc catatgttct gtagacatgg
    51301 gatcctccta gttttactca aaattgaata cgatgagtca ttttttgcga tactcccatt
    51361 ttatcataaa taagcaagaa attcacggat aatctttaaa aactaaaaag aacctgacgc
    51421 taaaatcact ggaaagaagt gaaagtatct cccgccccac tagcgatata gccaaatgct
    51481 gctttaggaa taacttgttg cgccattggc tccaaatcat ag
//
LOCUS       DAVLCS010000010        48274 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLCS010000010 DAVLCS010000000
VERSION     DAVLCS010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48274
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.010"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            59..223
                     /locus_tag="VXC78_000693"
     CDS             59..223
                     /locus_tag="VXC78_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV0582809.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            302..1030
                     /gene="yaaA"
                     /locus_tag="VXC78_000694"
     CDS             302..1030
                     /gene="yaaA"
                     /locus_tag="VXC78_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV0582810.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(1081..2565)
                     /locus_tag="VXC78_000695"
     CDS             complement(1081..2565)
                     /locus_tag="VXC78_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0582811.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            2781..9533
                     /locus_tag="VXC78_000696"
     CDS             2781..9533
                     /locus_tag="VXC78_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0582812.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAASVLLGTALVLGVAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTEEV
                     TKPAEKVEEAKDKKEEVTHQDAVDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADATEAELSAAESSIQSFIIGLELRSNSNKETVSETPVAKKADAVESKEGAK
                     PAATTERSAVDSAILPTSTADKVETTSAPASINEILKLGLSLSDARQNPAIRKENVNR
                     GYSGFRAASNPANPIVSGSGNTVAFADISQGGRSYSFRGYGNSRGGNSIHYDVTTVRS
                     GNSVNFTISYSAPGDSREFVNNNFILDKGDGFGNPSNATITSSNPRVREQSKSISQGA
                     NYVSHSGYSMTSAISTNTEQTIRFSLPIINLNGDLSVRLKPVTFNVDQGGGGAATSND
                     PYSNSNYYYRANPLYLDANPYGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEK
                     GQRQITYKVHRFGNETLLGLPISNSVTKEAKPRIMQIGVAKDLIDTVKPRVDQNKVGD
                     TNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAKGEKGDRGER
                     GLTGAQGAKGEKGDRGERGLTGAQGAKGEKGAQGERGLTGAKGEKGDQGERGLTGAQG
                     EKGDRGERGLTGAKGEKGAQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTV
                     VRDGFDGASPLVATQRNDADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKG
                     DKGEQGLQGRDGEQGPKGEDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDG
                     ASPLVSTHRNEADKTTTVIFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGK
                     DGFTPEVTVTDNNNGTHTITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTL
                     TFYIDKDGDGSYTAGKDELVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGD
                     TFVNTQTGDVFVKKGNTWEPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGEK
                     GDQGERGLTGSKGEKGDQGERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAG
                     PQGPKGEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRN
                     GTNGQSPTITATRSVQNGKNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQ
                     NGTHTLTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTET
                     GDVYVKNNGNWDKEGNIKGPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDG
                     RDGKDVLNGKANPEAHQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGE
                     DGKTPEVTVTPGKDGHSTDITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNG
                     NPSHTIVTFYTDENNDGKYTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKV
                     YQEDPANPGQPLNPEKPLAVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPT
                     TVFVQDGAKGETGATGQDGQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGK
                     DGRAPKIKVEDITSPSRIRRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSK
                     DIYNGIDGRDGSAPTITTKDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTEN
                     PDGSHTITVTNPDGSTKETVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAII
                     KDGKDGKAATATTTENPDGSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGD
                     GSHTIVITNPEGVTTETTVRDGKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGRE
                     PKLEVIDNNDGSHTIKVTGADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGRE
                     YKSIIKDGKDGKDSVSPTVTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSV
                     EDNGDGSHTITIINSDGTVTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSN
                     DKPVPPTPNVPTPEVPVKPVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQP
                     VVPTPAQPATPVNANPVAPTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRK
                     EA"
     gene            complement(9770..10318)
                     /locus_tag="VXC78_000697"
     CDS             complement(9770..10318)
                     /locus_tag="VXC78_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0582813.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            10639..11127
                     /locus_tag="VXC78_000698"
     CDS             10639..11127
                     /locus_tag="VXC78_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV0582814.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            11124..12311
                     /locus_tag="VXC78_000699"
     CDS             11124..12311
                     /locus_tag="VXC78_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0582815.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGGDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            12304..12528
                     /locus_tag="VXC78_000700"
     CDS             12304..12528
                     /locus_tag="VXC78_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0582816.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEV"
     gene            12685..14031
                     /gene="asnS"
                     /locus_tag="VXC78_000701"
     CDS             12685..14031
                     /gene="asnS"
                     /locus_tag="VXC78_000701"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV0582817.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPVAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            14184..14474
                     /locus_tag="VXC78_000702"
     CDS             14184..14474
                     /locus_tag="VXC78_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV0582818.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            14486..14956
                     /gene="ssbA"
                     /locus_tag="VXC78_000703"
     CDS             14486..14956
                     /gene="ssbA"
                     /locus_tag="VXC78_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV0582819.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVLDFSRNENPFGATNPLDISDDDLPF"
     gene            14988..15227
                     /locus_tag="VXC78_000704"
     CDS             14988..15227
                     /locus_tag="VXC78_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV0582820.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            15522..16922
                     /locus_tag="VXC78_000705"
     CDS             15522..16922
                     /locus_tag="VXC78_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV0582821.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGNPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            16924..17283
                     /locus_tag="VXC78_000706"
     CDS             16924..17283
                     /locus_tag="VXC78_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV0582822.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            17337..18086
                     /locus_tag="VXC78_000707"
     CDS             17337..18086
                     /locus_tag="VXC78_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV0582823.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            18076..18375
                     /locus_tag="VXC78_000708"
     CDS             18076..18375
                     /locus_tag="VXC78_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV0582824.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            18446..19381
                     /locus_tag="VXC78_000709"
     CDS             18446..19381
                     /locus_tag="VXC78_000709"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV0582825.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            19468..19980
                     /locus_tag="VXC78_000710"
     CDS             19468..19980
                     /locus_tag="VXC78_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV0582826.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDEEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            20005..20613
                     /locus_tag="VXC78_000711"
     CDS             20005..20613
                     /locus_tag="VXC78_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV0582827.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKASLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            20714..20896
                     /locus_tag="VXC78_000712"
     CDS             20714..20896
                     /locus_tag="VXC78_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0582828.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGLKNVFTK"
     gene            complement(20942..22387)
                     /locus_tag="VXC78_000713"
     CDS             complement(20942..22387)
                     /locus_tag="VXC78_000713"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV0582829.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGVDCYQIIQGKKESYPGDTAVAENYL"
     gene            22493..24115
                     /locus_tag="VXC78_000714"
     CDS             22493..24115
                     /locus_tag="VXC78_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0582830.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            24318..26276
                     /locus_tag="VXC78_000715"
     CDS             24318..26276
                     /locus_tag="VXC78_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0582831.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            26448..26681
                     /locus_tag="VXC78_000716"
     CDS             26448..26681
                     /locus_tag="VXC78_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEV0582832.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            26687..28129
                     /locus_tag="VXC78_000717"
     CDS             26687..28129
                     /locus_tag="VXC78_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0582833.1"
                     /translation="MRKKVIEGLIYAEKSFFDKSQSGELTSAIVNDTSVIREFLITTF
                     PNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMMFIILPLSNISEKYSRRLQEEIG
                     FLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRITSFETPFALLFI
                     FATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVYSRSKGSSVA
                     LENLLAVPKEKFEGGKSVSGRGLNFNHVYFGYDENRPVLKDIICSIFKGQKIAFVGPS
                     GSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDN
                     LCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGQSQRLQIARA
                     YLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFFLE
                     EGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            28287..29381
                     /locus_tag="VXC78_000718"
     CDS             28287..29381
                     /locus_tag="VXC78_000718"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0582834.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGSKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            29389..30555
                     /locus_tag="VXC78_000719"
     CDS             29389..30555
                     /locus_tag="VXC78_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0582835.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            30648..33746
                     /locus_tag="VXC78_000720"
     CDS             30648..33746
                     /locus_tag="VXC78_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0582836.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVDRQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAIQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKTDLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILADNHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVIYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            33794..34411
                     /locus_tag="VXC78_000721"
     CDS             33794..34411
                     /locus_tag="VXC78_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0582837.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            34422..35756
                     /locus_tag="VXC78_000722"
     CDS             34422..35756
                     /locus_tag="VXC78_000722"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV0582838.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            35766..36230
                     /locus_tag="VXC78_000723"
     CDS             35766..36230
                     /locus_tag="VXC78_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0582839.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            36227..36721
                     /locus_tag="VXC78_000724"
     CDS             36227..36721
                     /locus_tag="VXC78_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0582840.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            36802..38457
                     /gene="mltG"
                     /locus_tag="VXC78_000725"
     CDS             36802..38457
                     /gene="mltG"
                     /locus_tag="VXC78_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV0582841.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            38528..39010
                     /gene="greA"
                     /locus_tag="VXC78_000726"
     CDS             38528..39010
                     /gene="greA"
                     /locus_tag="VXC78_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV0582842.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            39518..39916
                     /locus_tag="VXC78_000727"
     CDS             39518..39916
                     /locus_tag="VXC78_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0582843.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            40361..41368
                     /locus_tag="VXC78_000728"
     CDS             40361..41368
                     /locus_tag="VXC78_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0582844.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            41443..41643
                     /locus_tag="VXC78_000729"
     CDS             41443..41643
                     /locus_tag="VXC78_000729"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV0582845.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            41678..42394
                     /gene="atpB"
                     /locus_tag="VXC78_000730"
     CDS             41678..42394
                     /gene="atpB"
                     /locus_tag="VXC78_000730"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV0582846.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            42408..42902
                     /gene="atpF"
                     /locus_tag="VXC78_000731"
     CDS             42408..42902
                     /gene="atpF"
                     /locus_tag="VXC78_000731"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV0582847.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            42902..43438
                     /locus_tag="VXC78_000732"
     CDS             42902..43438
                     /locus_tag="VXC78_000732"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV0582848.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            43453..44958
                     /locus_tag="VXC78_000733"
     CDS             43453..44958
                     /locus_tag="VXC78_000733"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV0582849.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            44974..45852
                     /locus_tag="VXC78_000734"
     CDS             44974..45852
                     /locus_tag="VXC78_000734"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV0582850.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            45938..47344
                     /gene="atpD"
                     /locus_tag="VXC78_000735"
     CDS             45938..47344
                     /gene="atpD"
                     /locus_tag="VXC78_000735"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV0582851.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            47355..47774
                     /locus_tag="VXC78_000736"
     CDS             47355..47774
                     /locus_tag="VXC78_000736"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV0582852.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(47846..>48274)
                     /locus_tag="VXC78_000737"
     CDS             complement(47846..>48274)
                     /locus_tag="VXC78_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0582853.1"
                     /translation="RKLSDKHFYRPTFRMHLTNKEILDKLLSYSQDLKHHYQLYQLLL
                     FHFQNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLPYSNAKLEATNN
                     LIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT        15151 a         8838 c        10726 g        13559 t
ORIGIN      
        1 tttatttaat aaatatatgt tataatagag taaattaaga ctaatggagg acaaagaaat
       61 gggtttttat ttgatggttg cttcaatgct actcggactg ctcgctttga agataggttt
      121 ttctcagttc aaggagaaaa aagataaatt cttatctatc ttaacaagtt tagctggcac
      181 agcccttgtt ctcgtggctg tctggttagg atggcccaaa taaatagaaa aacctcggtc
      241 aaaccgaggt ttttcaaatg aatttcttgg ttgtggctaa aaaatatgct acactatcaa
      301 tatgaaaatt ttaatcccaa cagcaaaaga aatgaacaca gacttgccaa gtatcgaggc
      361 aattccttta aaaccagaaa gtcagaccgt gcttgatgcc ttggctctct attctgccag
      421 tcaattggag agtttctaca aggtatcagc tgagaaagcg gcggaagaat ttcaaaatat
      481 ccaagctttg aaaaggcaaa ctgctcaaca ctatccagcc ttgaaacttt ttgatgggct
      541 tatgtaccgc aacattaaga gagataagct gaccgaggcg gaacaagatt atcttgaaaa
      601 tcatgtcttc attacctcgg ctttgtacgg tgttgttcca gccttgtcac ccatggctcc
      661 tcaccgtttg gattttttga tgaaattaaa agtcgctggt aagactttga agagccattg
      721 gaaggcagtc tatgatgaag ctctgaagaa ggaagaagtg attttctctc tcttgtcatc
      781 agagtttgag actgtatttt ctaaggaaat cagagcaaag atggtgacct tcaaattcat
      841 ggaggataga ggcggtcagc tgaagattca ctcaactatc tccaagaaag cgcgcggggc
      901 ctttctaaca gctttaatag aaaatcaagt acaaactgtg ggggaagcac gtcgcttgaa
      961 ctttgctgga tttgtttacc gagaagattt gtcacaacca cagggattgg tttttgtaaa
     1021 ggaagtatag aaatcagata agagaaaagt cagcacgatt atgctgactt ttttgataac
     1081 ttataaagta ttggacaaat gaatctcatt tgataaggtg ttaagatgat taaccaaatt
     1141 catgattgac agatgatttc ggcaaataaa cttcttggta atccctggaa tatagaaatt
     1201 agacacgatg atatcgtaat ctgtctgatt taaaatctca ggacttgttt ttaattcatc
     1261 ccaaatatcg aaggtaaagc ggttattaca gtaataggaa agcatatcaa caaaggtaag
     1321 ggatatagca tggtcaaagt tactgataat caaaaccttg ataggtggtc gattttctaa
     1381 caactgagta gagaggtttt cagcatgggt taagatggtg tacatcaagt gttccaactg
     1441 ttcaggatgg tcatgctgtc caattgcctg acggtattga gccagttctt gacgcgcact
     1501 tcccataaag tctgggaagt aaacttcaaa ttttttaatc gtcaatgctt tttgttcaaa
     1561 taagattggg gtagaaaaga tttcttgtct ttcaaagaaa gcagtgttgt gtaaatgcca
     1621 aatcagctca tcgtggttag taaaagtaat cttatattgt tttgataggc gttctaatat
     1681 ttgactaagt aattggtaag agtatcttgc ttgactgtta tcttctaaag agttgaagaa
     1741 ttcttgagga tctaggaaaa tatcattctg aagaaaagaa ataaaaattt gagcgattgt
     1801 atctggagtc atttcaagcc caaaatgttt agagaaataa gcaagtgtct cctggaaatt
     1861 tggaatgctc tttaaaagag gataatattc tttgtaaaag tggttgggga ggtcaatgaa
     1921 gtgaccattt ttaaccctgt ggatactaat agctatcatc agtttgtaca ttctataaat
     1981 tgaaaatcgc attggataat tcgtgatttt atagaagaag tcagcaaact ctgttaaatc
     2041 ttcctcagga aggtcaggaa aaggccaatc taggaaataa tagcgctcag aaaagtattg
     2101 ggcaaaaaag taacgaatat cgatctcatt tccacgtatc tcggatggag taaaagataa
     2161 ttcaatttga aactgagatg aaagaacctt tgtaatattt ctgcccagtc gatagaggtt
     2221 ggcactacta aagtaaagat tttctattgt tcgataaata ggtagcccct cattgaagaa
     2281 catatactct agtaattgaa aagattgaga attagcaaga aaatattgat aaatatcttc
     2341 tacactagtg ttaacttcta aatctatcat gattccgtta acagaagatt ggatgttaat
     2401 agatggaaag gcaatacgta attcatttaa atcacttttt aagattcgtt ctgtacatcc
     2461 taatttttcg gctagttcat gtaatttcat ccaattacga ttctgaatta gggtttccat
     2521 taagcgtaat tgtctttgaa cttttgtgga taaaaggttt ctcatacggg tatttcctcc
     2581 ataattcatt atatcttttt ttgtctaagt agtataaaaa aattagagca agaaaattgt
     2641 cgttagtaat cggaaaaatt agaataatat aagtggcttt taagtgcaga aacagagtat
     2701 attaattgtt cagaaaatat tgattaatgc ctcaaatagt tgtacattgt aaactataaa
     2761 atactatcta ggagtttaaa atgaaacatt cacataaaaa atcatttgac tggtatagca
     2821 tgcaacaacg ttattctatt cgtaagtatt actttggtgc agctagtgtc ttgctcggta
     2881 ccgctttggt attaggtgta gcagctagtg tccaaacagt acaagcggaa gaaaacaaac
     2941 aagaaactac caatagtatt tctgttggta ggggagaagc agctactaaa ccagcagagg
     3001 tttctgcgtc taataaagag aaaacctatg cagctccaac tgtagctaat ccagtagaaa
     3061 cgactccagt taaaactgaa gaagttacta aaccagcaga aaaagttgaa gaagcaaaag
     3121 acaaaaaaga ggaagtaacg catcaagatg ccgttgacaa gtcaaaatta ttaacggctc
     3181 tttcgcgtgc taaaaaatta gaaagcaagt tatatacaga agcaagtgct gctaacttgc
     3241 aaacaagtat ccaagctggt caaagcttgc ttggaaaagc agatgcaact gaagctgaat
     3301 tatcagcagc agagtcatct attcaatcat ttattattgg tctagaactt cgttctaact
     3361 ctaataaaga aactgtatca gaaacgcctg tagcgaagaa agctgatgca gttgaatcaa
     3421 aagaaggggc taaaccagct gcaacaactg aacgttcagc tgttgatagc gctattttgc
     3481 caactagcac agctgacaaa gtagaaacaa cttcagctcc agcatctatt aatgaaatct
     3541 tgaaactagg tttgagcctt tctgatgctc gccaaaatcc agctatccgt aaggaaaatg
     3601 ttaatagagg gtatagtggt tttagagcgg ctagcaatcc agccaaccca attgtctcag
     3661 gttctggaaa tacagttgca tttgcagata ttagccaagg tggtcgtagc tatagtttcc
     3721 gtggctacgg gaactcacgt ggtggaaatt ctattcatta cgatgtaaca acagtacgta
     3781 gtggtaatag tgttaacttt acaattagtt attctgcgcc aggagattct agagagtttg
     3841 ttaataataa ttttatcttg gataaagggg atggatttgg aaatccttca aatgcaacga
     3901 tcacaagttc aaatccaaga gtaagggagc aatcaaaatc tattagtcag ggtgccaact
     3961 acgtatctca ctcaggatac agtatgacct ctgctatttc aacaaatacg gaacaaacta
     4021 tcagatttag tttgcctatc attaatctaa atggtgattt gtctgttcgt ttgaaacctg
     4081 ttacttttaa cgtggaccaa ggtggtggtg gtgccgctac tagcaatgac ccatacagta
     4141 actctaacta ttattataga gcaaacccac tatacttgga tgcaaaccct tatggtggta
     4201 ctaataataa gactgtttca gaagacattg acttccaaac tgtctatctt ccaactagta
     4261 agttaccaga aggtcaaact agattagttc gagaaggtga aaaaggacaa cgtcaaatta
     4321 cctataaagt tcatcgattt ggtaacgaaa cacttttagg attgccgatt agtaatagtg
     4381 ttactaaaga agctaagcca cgtattatgc aaattggtgt ggctaaagat ctaatcgata
     4441 cagtaaaacc acgtgttgat caaaataaag tcggtgatac aaataacctc actttctatc
     4501 ttgataacga tggaaacggt gtttatactg aaggtgtaga cgaacttgtt caaaaaattg
     4561 ctattaaaga tggagctaaa ggtgaaaaag gagaccaagg tgaacgcggt ctaactggag
     4621 ctaaaggtga aaaaggagac cgaggcgaac gcggtctaac tggagctcaa ggagctaaag
     4681 gtgaaaaagg agaccgaggc gaacgcggtc taactggagc tcaaggagct aaaggtgaaa
     4741 aaggagccca aggtgaacgc ggtttaactg gagctaaagg tgaaaaaggg gaccaaggtg
     4801 aacgcggtct cactggagcc caaggtgaaa aaggagaccg aggcgaacgt ggtttaactg
     4861 gagctaaagg tgaaaaagga gcccaaggtc aggcaggtcg tgacggtgta actccaaccg
     4921 taaccgttaa agataataaa aatgacggca ctcatactat cactattaac gacggtagag
     4981 gtaatgttac aagtactgtt gtaagagatg gtttcgatgg cgcaagtcca ttagttgcga
     5041 ctcaacgaaa tgacgcagat aagacaacaa ctgttatctt ctattacgat aaaaatggaa
     5101 acaatgaatt agatgcttct gataagaaat taaaagaagt tgtaattgca gatggtgcta
     5161 aaggtgaaaa aggggacaaa ggtgaacaag gtcttcaagg gcgtgatggt gaacaaggac
     5221 caaaaggaga agatgggaaa accccaacag ttaaagtaac tgatggtcaa gatggaacgc
     5281 atacaattac aattaacgat ggtaaaggtg gtataactac tacagtagta agagatggat
     5341 ttgatggtgc aagccctctt gtttctactc atagaaatga agcagataaa acaacaactg
     5401 ttattttcta ttatgatcta aatgataata atcaatttga tgaaggagat acaaaactta
     5461 aagaagttgt tatcgcagat ggaaaacaag gaccaaaagg tgacaaaggt gataacggaa
     5521 aagatggatt cacaccagaa gtaacagtta cagataacaa taacggaaca cacaccatca
     5581 caatcacaca accagacaac agaccatcat taacaacaat cgttaaaaac ggtgaagatg
     5641 gaaaaacacc aaaagtcaaa gcagaacgag atgatgcgaa gaaacaaaca acattaacat
     5701 tctacattga caaagatgga gatggaagtt acacagcagg aaaagacgag ttagttcaaa
     5761 caacagtagt taaagacgga caagacggag ctgcaggagc atctggacgt gatggaaaag
     5821 aagtattaaa cggaaaagta gacccaacaa cagaaggtaa agatggagac acattcgtaa
     5881 atacacaaac aggagatgta ttcgttaaga aaggtaacac ttgggaacca gcaggaaaca
     5941 tcaaaggacc gaaaggtgac aaaggtgcag atggtgccaa gggtgaaaaa ggagcccaag
     6001 gagaacgcgg cctgactgga gcgcaaggtg tcaagggtga aaagggagat cagggtgaac
     6061 gcggtctaac tggatctaaa ggtgaaaaag gagaccaagg tgaacgcggt ttaactggag
     6121 cgcaaggtgc caaaggtgac aaaggtgaac aaggtcttca aggtcgtgat ggagctcaag
     6181 gaccaaaagg cgcagatgga caaagaggac cagcgggacc acaaggacca aaaggagaac
     6241 aaggtaatcc aggaactcca ggtaaagatg gaaaatctct aattgctgtt aaaaatggaa
     6301 ctgaaacaaa agtctatgta gaggatccgg ctagaccagg acaaccactt aatccaaacc
     6361 aaccattagc aactatcact gatggaagaa acggtactaa tggacaatca ccaacaatta
     6421 cagcgacacg aagtgtgcaa aatggcaaaa atggtgtatt agtaacaatt acaccagtag
     6481 gaggtcgtcc acaaacaaca tttgtagagg atggacaaaa gggtgctgat gggaaaaccc
     6541 caacagtaac aataactgag gggcaaaacg gcacacatac attaacggtt cataatccag
     6601 gaagtccaga tgtgacaact acgatccgtg atggagctac aggacaagca ggtcgtgatg
     6661 gtaaagatgt attaaacgga aaagtaaatc cacaaccaaa ccaaggtaaa aatggagata
     6721 aatatattaa taccgaaacc ggtgatgtct atgttaaaaa caatggaaac tgggataaag
     6781 aaggcaacat caaaggccct aaaggggaca aaggtgcaga tggtgctaaa ggcgaaaaag
     6841 gagaccaagg cgaacgcggc ctaactggag cgcaaggagc taaaggtgcg gatggcgcag
     6901 taggtcgtga tggacgtgac ggtaaagacg tgttgaacgg caaagctaac ccagaagcac
     6961 atcaaggtaa agacggcgat aaatacgtta atacagaaac aggcgacgtc ttcgttaaga
     7021 ataacggcaa ctgggataaa gagggcaaca tcaaaggccc taagggtgac aaaggtgaac
     7081 gcggagaaga tggtaagact ccagaagtaa ctgtaactcc aggtaaagat ggccatagta
     7141 ctgacattac attcactgtt ccaggtaaag atccagttac agtaaatgtt aaggacggag
     7201 aaaatggtct gaacggtaaa actccaaaag ttgatttact tcgtgtccaa ggaaaaaacg
     7261 gaaatccatc tcatacaatt gtgacattct atacagatga aaacaatgac ggcaaatata
     7321 caccaggaac tgatgaactt ctaggttcag aaatgattaa agatggtgct aaaggcgcgg
     7381 acggacgaga tggtaaatca ttgcttactg tcaaggatgg taaagaaact aaagtttacc
     7441 aagaagatcc agctaaccca ggacaaccat taaatccaga aaaaccactt gcggtaatta
     7501 gagatggagt agatggaaaa tcacctacag ttacagctgt tcgtaaagat gaagcagggc
     7561 ataaaggtgt agaaatcact gttgataacc atgatggttc acaaccaact acagtctttg
     7621 ttcaagatgg tgctaaggga gaaactggtg caaccggtca ggatggacaa actcctacaa
     7681 tcactactca acgtggacaa gatggccaaa gcactgttgt aactatcaca acatcaggta
     7741 aagatccagt aaccttcact gtaaaagatg gtaagaatgg taaagatggc cgtgcaccga
     7801 aaatcaaagt agaagatatt acttcacctt caagaattag acgcgataca gatgctgctg
     7861 caactccaac gcgtaacggt atccgtgtta cagtttatga tgatgttaat gacaatgggg
     7921 tatacgacga aggtgtcgat aaagtattaa atagtaaaga tatttataac ggtatagatg
     7981 gacgtgatgg ttcagctcca actattacta caaaagataa tggagatgga actcacacta
     8041 tcacagttca aaacccagat ggttctgaat caacaacagt tgttaaagat ggtaaagacg
     8101 gtaaaactgc gaatatcact acaacagaaa acccagatgg aagccacaca attacggtga
     8161 caaatccaga tggttcaact aaagaaactg ttgttaaaaa cggtaaagac ggtaagactc
     8221 ctaaagttga agtaacggat aacaacgatg gaactcatac tgttaaagtt acagatggag
     8281 acggcaatgt taccaacgct atcatcaaag atggtaaaga cggtaaagct gcaacagcaa
     8341 caactactga aaatccagat ggaagccaca cagtaacaat cactaaccca gacggaacta
     8401 agaatgagtt tgttgttaag aatggacgtg acggtgttga cggacgtact ccaaccgcat
     8461 ctgttcgtga taatggagac ggaagtcata caatcgttat tacaaatcca gaaggtgtga
     8521 caactgaaac cacagttcgt gatggtaaat caccaaaagt gactataact gatgaacaaa
     8581 atggaactca taagatctct gttctaaatg gtgacggaac aactacaaca actacagttc
     8641 gtgatggtag agaaccaaaa cttgaagtta ttgataacaa cgatggttca cacactatta
     8701 aagtgacagg tgctgatggt aaaggaacga caactacaat ctttgatggt aaatcaccaa
     8761 aagcgaacat cgttgataac ggagatggaa ctcatacatt aacaatcgta gattctgatg
     8821 gtcgtgaata caaatctatt atcaaagatg gtaaagacgg caaagatagc gtttcaccaa
     8881 ctgtaactgt taaaaataat aacgatggaa ctcacgttgt tacaatcact aatccagatg
     8941 gaagtaagac agaaatggtg attaaagacg gtaaagatgg taaatcacca aaagtttctg
     9001 ttgaagataa tggtgatggt agtcatacaa tcacaatcat caattctgat ggaactgtga
     9061 caaaaacagt tattaaagat ggtagagatg gacgtgatgg tcgagacggc aaagacggta
     9121 aagacggtaa agatggaaaa tgtggatgcc aagacaaacc agtaacacca tcaaatgaca
     9181 aaccagttcc tccaacacca aatgtgccga caccagaagt accggttaaa cctgtgccag
     9241 cgcaaccaac accaaatgta ccgacaccag aagtgccagt acaaccaact ccagctgttc
     9301 caacaccaga agtaccggtt aaaccagtac cagcggttcc agaacaacca gtagtaccaa
     9361 caccggctca accagcaact ccagtaaatg ctaacccagt agcaccaact acaggtaaag
     9421 aaaaccgtgg ggacaaatta cctgaaactg gaagccaatc tgattatatc tctgttcttt
     9481 taggtagcgg tattctattg agcctatatg taggacgaag aaaagaagct taatcagcca
     9541 aaagcagtca ctaatttctc gaaagaagat gataagtgat agatctcgaa tgaaagaata
     9601 ttcttagaat gattttccta tgatggaaaa gactgctaaa aaccttgagt ggtaacgctc
     9661 aaggtttttt tggatggctg atgtttgtct gaaaatcttg attgagaaat aaaaagccac
     9721 cctattaggt ggctataatt gatttagact ttctaaaatt ttctattttt tactgaatcg
     9781 cttcgaccaa gtcttgagct tgtttttcaa gtgagtttag gactgtttct tcaagaacca
     9841 attttccgtc tgcccaggca gagtcattaa cacgtgcagc agtgaaatca ccaacgcctt
     9901 gtgtacggat aaatggcaag aggtctttgt agatagcgaa aagttgatcg tgccctgcat
     9961 tggctacaga tgatacggtg acaaacttgt cttgaagggc agaaacgcca cgcgtatcag
    10021 acaagtcaag ggcacgagat agccagtcaa gcaagttttt tactgtacca gggatagaga
    10081 agttgtagac tggagagaaa atccagatag catccgcaac gagaactgct tcacgagcag
    10141 cagctacagc tggatgtgtt ggaacttcca aatcttggct gaagagagga agggctgaat
    10201 aatcaaggta gctaacttcc gctttaccag caagtgcttt ctcagcttcg agcgccattt
    10261 ggtggttgaa agaaccttga cgtagtgatc cgacgataaa taatactttt ttagacatga
    10321 tgtgtctcct ttttcttcaa attttgagaa ctctctcgtt gttataaaat acattacaac
    10381 aaaacaaaag aacttgcaag aaatttgctc agagtttatt tgaaaattgt aaaatttcgg
    10441 aaactctagt catttgtgac tgaaaaagta agaactgttt cactttcaaa atcggttttg
    10501 tttgaaggga gaaatagaat tggttgctca aagcacagct ttgaggttgc agataaagct
    10561 gacgtggttt gaagagattt tcgaagagta ttcttatatt cacttgtaat aaagcttaat
    10621 agatggtaaa atagacgagt gaaaaaaaga caaaacaaag caaaaaataa tctactgtgg
    10681 cagtatggtc tagggatgac gattttgttt gtggttatca gtgcttcctt tctgtatatg
    10741 gtttctctta gcatgaaacc ctatcaaaca gctaaaagtg aaggagaaaa attagctcag
    10801 cagtatgcag gattagagca ggccgatcag gttgatttat acaatggctt ggaatcttat
    10861 tacagcgttc ttggtcgtaa taaacagcaa gaagcacttg ctgttctgat tggaaaagat
    10921 gatcataaga tttacgttta tcagctaaat cagggtgttt cacaagaaaa agcagaaacg
    10981 gtttctaagg aaaagggagc tggcgaaatt gacaagatta tctttggtcg ttatcaagat
    11041 aagccaatct gggaagtcaa gtcaggatct gatttttatc tagtagattt tgaaacagga
    11101 gcattggtca acaaggaggg cctatgaaat tatccaaccg tgttttagaa atggaagaaa
    11161 gtgtgacttt ggctgctgga gcccgtgcca aagcactgaa ggctgagggt ggagatattt
    11221 tgtctctaac cttgggtgag ccagatttca ctactcccaa aaatatccaa gatgccgcca
    11281 ttgcatcgat tcgagatggg cgtgcttctt tttatacagt aacctcaggt ctgccagagc
    11341 ttaaggcggc ggtcaatagc tactttgagc gcttttacgg ctattctgta gcgtcaaatc
    11401 aagtgacagt cgctgcggga gccaaatatt ctctctatac cttctttatg gctgtggtca
    11461 atccaggtga tgaagtcatc atcccaaccc catactgggt tagctatgga gatcaggtca
    11521 agatggcaga aggcgttccc gtctttgttt ctgctaagga agacaatcac tttaaggtga
    11581 ccgtagagca gttagaagca gctcgcactg acaagaccaa ggttttggtg ctgaattcgc
    11641 catctaatcc cacaggtatg atttacaccc gtgaggaact cttggcaatt ggaaactggg
    11701 ctgtagaaaa tgatattctc atcctagcag acgatatcta tggccgcttg gtttataatg
    11761 gtcatgagtt cacaccgatt tctagcctat cggaagcgat tcgcaagcaa acagtggtca
    11821 tcaatggtgt gtctaaaacc tatgccatga ctggttggcg gattggttat gccgttggag
    11881 aagcagacat tatcgctgcc atgtccaaga ttgcaggtca aacaacttcg aatccgtcag
    11941 cagtagccca atatgcagca gttgaggctc tatcaggtga gcaagatact gtagaaagca
    12001 tgcgtcaggc ctttgaggaa cgtcttaata ccatctatcc cctccttgca gaggtgccag
    12061 gatttgaagt ggtcaaaccg caaggggcct tctatctctt cccaaatgtc aaaaaggcca
    12121 tggagatgaa aggctacacg gatgtgacag actttacaac tgctatctta gaagaagccg
    12181 aagtggcctt ggtaacagga gctggatttg gagcaccaga aaatgtccgc ctcagctatg
    12241 cgacagacct agacacgctt aaagaagcag tcgaacgctt gaaagcattt atgggtagtg
    12301 agaatgattg atcattttga gattaaggta aaggatttac aaatttcaga aggattttat
    12361 aggagttttc tcgctccttt ggactataaa ttggctttta agactagttc tctaattagt
    12421 tttctatccc cgaacagccc tcatcctggt ggtgattttt ggctgactca gggaacacaa
    12481 gatcctgttc attttgcttt tttagcagaa aataaggaag aagtttaggc ttgttatgag
    12541 gctggcttag aggcaggtgg gcgagataat ggggctcctg gttatcgaag tgagcgtccg
    12601 atttactatg ctgcttttat gattgacctg gatgggaaca atatagaggt ggtttgccat
    12661 aaagaataaa aaagaaaagg aaaaataatg acaaaacgtg taacgattat tgacgtaaaa
    12721 gactatgttg gtcaggaagt gacgattggc gcttgggttg ccaataaatc aggaaaaggg
    12781 aaaatcgctt tcttacaatt gcgtgatgga acagccttct ttcaaggtgt ggcttttaaa
    12841 ccaaactttg tcgaaaaatt tggtgaagaa gtgggacttg agaagtttga tgttatcaaa
    12901 cgcttgagcc aagaaacgtc tgtttatgtg acaggtattg tcaaagagga cgaacgttct
    12961 aaatttggct atgagttgga catcacagac atcgaagtga tcggtgaatc tcaagactac
    13021 ccaatcacac caaaagaaca cggaacagac tttttgatgg ataaccgtca cttgtggcta
    13081 cgctctcgta agcaagtagc tgtgttgcaa atccgtaacg ctattatcta tgcaacttat
    13141 gagttctttg acaagaacgg ttttatgaag tttgacagcc caattctttc aggaaatgcg
    13201 gcagaagatt ctacagaact ctttgaaact gactacttcg gaacgccagc ctacttgagc
    13261 caatcaggtc agctttacct agaagcaggg gctatggctc ttggtcgtgt ctttgacttt
    13321 ggtccagttt tccgtgctga aaaatcaaaa acacgccgtc acttgactga gttctggatg
    13381 atggatgctg agtactcata cttgacacat gatgagtcgc ttgacttgca agaagcttat
    13441 gtgaaagctc ttctacaagg tgttcttgac cgcgcgcctc aagccttgga aaccttggaa
    13501 cgtgatacag aactcttgaa acgctacatt gcagagccat tcaaacgtat cacttacgat
    13561 caagccattg acctcttgca agagcatgaa aatgatgaag atgctgacta cgagcatctt
    13621 gagcatggtg atgactttgg gtcaccacac gaaacttgga tttcaaacca ctttggtgtg
    13681 ccaacatttg tcatgaacta tccagtagcc atcaaggcct tctacatgaa accagttcct
    13741 ggaaatccag agcgcgtgct ttgtgcagac ttgcttgctc cagaaggcta tggagaaatt
    13801 atcggtgggt ctatgcgtga ggaagattac gatgcccttg tcgctaagat ggatgaactt
    13861 ggcatggatc gtacagaata tgaattctac cttgaccttc gtaaatacgg tacagttcca
    13921 cacggaggat ttggtatcgg tatcgaacgt atggtaacct ttgcagcagg aacaaaacat
    13981 atccgtgaag ctattccatt cccacgtatg ttgcaccgta tcaaaccata agaacaggaa
    14041 aacgcccatg tggcgttttt tcgaattcta gtgtttttac ttgcgtaaaa aaattttttc
    14101 tagtataata gtttattgtg agcgaacctc acttacccct tgcaaagtct tggggtcatt
    14161 agaccaaaag gaggaacata tcaatggcta aatacgaaat tctttatatc attcgtccaa
    14221 acattgaaga agaagctaaa aacgctttgg tagcacgttt tgactctatt ttgactgaca
    14281 acggtgcaac tgttgttgaa tcaaaaactt gggaaaaacg tcgtcttgca tacgaaatcc
    14341 aagatttccg tgaaggactt taccacatcg ttaacgttga agcaaatgac gatgcagctc
    14401 ttaaagagtt tgaccgtctt tcaaaaatca acgctgacat tcttcgtcac atgatcgtca
    14461 aaattgacgc gtaagaaggt aaactatgat taacaatgtt gtacttgtag ggcgtatgac
    14521 acgtgacgct gagttgcgtt ataccccatc aaatgtagca gttgcgactt ttactcttgc
    14581 agtaaaccgt acatttaaga gtcaaaatgg tgaacgtgag gctgatttta tcaatgtcgt
    14641 tatgtggcgc caacaggctg aaaatcttgc taactgggct aaaaaaggct cacttatcgg
    14701 ggtgacaggt cgtatccaga ctcgtagtta cgataaccag caaggacaac gtgtctacgt
    14761 gacagaggtc gtggctgaga atttccaaat gttggaaagc cgtagtgtgc gtgagggtca
    14821 cacaggtgga gcttactctg caccaactgc aaactattca gcacctacaa attcagtact
    14881 agacttttca cgtaatgaaa atccatttgg agcaacaaac ccattggata tttcagatga
    14941 tgatttacca ttctaatgga caactaaact tataaaggag aaaaaacatg gctcaacaac
    15001 gtcgtggcgg attcaaacgc cgtaaaaaag ttgattacat cgcagcaaac aaaattgaat
    15061 atgttgatta caaagatact gagcttctta gccgtttcgt ttcagaacgt gggaaaatcc
    15121 ttcctcgtcg tgtaacagga acttcagcta aaaatcaacg taaagtaaca acagctatca
    15181 aacgcgctcg cgtaatggct ttgatgcctt tcgtaaacga agattaaaga aaagacccgg
    15241 ttgggtctct ttttcatgag cttgaaaaca agaaagcgaa ttaagacccc aatgggtctt
    15301 ttttcacaaa ctttgaaatg agagagcgag ttaggctcag tggctccctt tttacgagtt
    15361 tgaaaacaag agaacacatt aaaagcacga tggagctttt tcataaatat gtcttttttc
    15421 tcatccaaga aattaaaata aaaatgataa actttttgaa aataggggat ttgcctactt
    15481 tatgatataa tggaaagagt tagattgaaa gaggtagtga gatggacgcg aaattaagat
    15541 acaaggcaaa gaagatcaag attgtctttt ttgatattga tgatacattg cggaattcaa
    15601 agacagggtt tattccaact acaattccca ctgtttttaa acagttgcgt gaaaaaggaa
    15661 ttttaacagg aatcgcctct ggacgtggca tttttggtgt tgttccagag attcgtgatc
    15721 tcaagcctga cttttttgta actttgaatg gggcttatat cgaagataaa aaaggtcagg
    15781 tcatttatca gcatcagatt gaaaagtcag atgttgagga gtatatctct tgggctaagc
    15841 aagaaggaat tgagtatggc ttggttggga gtcatgatgc caagttgtcg actcgcaccg
    15901 atatgatgag tgaagctatc aatccaattt atcccgactt agatgtagat cccgatttcc
    15961 atgaaaaaga agatatctat cagatgtgga cttttgaaga taagggagat gacttgcact
    16021 tgcctgacag tctctcagac aaacttcgca tggttcgttg gcatcaacat tcgtctgata
    16081 ttgtgccgat ttcaggctcc aaagcgacgg gggtggaaaa agttgtggaa caccttggct
    16141 tgaaaccaga gaaggtcatg gtttttggag atggtctcaa cgacttggaa ctctttgatt
    16201 atgctggaat cagcgttgcc atgggaattt ctcatgataa aatcaaagaa aaagcagatt
    16261 atattacaaa aacattagaa gaagatggca tttttgatgc cttagaagta tttggtatgg
    16321 tagaaaaaga attgcatttt ccacaagtag acattgaaac agtagaaggt cctcttgcga
    16381 ctattaagac caatcacgga gacttacgta tcaagctttt ccctgaacat gctcctaaaa
    16441 cagtggctaa ctttgtatct ctttcaaaag atggctacta tgatggtgtc attttccacc
    16501 gtattatcaa ggactttatg atccaaggtg gaaacccaac tggaactggt atgggtggcg
    16561 agtcaatcta cggcgaatct tttgaggatg aattctcaga agagctttac aatatccgtg
    16621 gtgctctttc catggcaaat gctggtccaa ataccaacgg cagccagttc tttatcgtgc
    16681 aaaaccaaca cctaccttat tctaagaaag aaattactcg tggtggttgg ccagaaccga
    16741 ttgcagaaat ctatgccaat caaggtggga cacctcacct agaccgtcgt cacacggttt
    16801 ttggtcagtt agctgatgaa gcatcttacg ctgtcttgga tgccattgct gctgttgaga
    16861 caggagctat ggacaagcca gttgaagatg ttgtaattga aactattgaa atcgaggact
    16921 aagatgaaaa tcggtgataa gctaaagggg cgtattacag ggattcagcc ctacggtgcc
    16981 tttgttgagt tagagacggg tgatacgggg ctgattcaca tttcagaaat tcggacagga
    17041 tttattgaaa atattcatga aaccttgaaa gtcgatgaag aggttcaagt tcaggtagtg
    17101 gatttagatg aatttacggg gaaagccagt ctttctatcc gcactttgga ggaagaaaag
    17161 taccagtttc ctagacggag acgcttttca agcgaccgct ttaactacgg ttttgctccc
    17221 tttcgacgaa tgctaccaat ctggactgga gaagccctgc accatttaaa aaagaagaag
    17281 tagtttagag ttttatattt tttgtaatgt taatataaat ttgctataat aggaccatgg
    17341 aagaagaaca attattaaaa tcaggagagc gcattaacca gctcttttcg acagatatca
    17401 aaatcattca aaatagagag gtttttagct attcggtgga tagtgttctc ttatcacgat
    17461 ttccacgttt tcctaagaag gggttgattg tggatttctg tgctgggaat ggagcagtgg
    17521 ggctttttgc tagcactcgt actcaagcac agatattgtc tgttgagatt caggagcgtt
    17581 tggcggatat ggctgaacgc tctgtccgtt tgaatggatt agaggagcaa atgcaggtca
    17641 tctgcgatga tttgaaaaat atgcctgctc acattcaggg gagtaaggtg gatatgattt
    17701 tgtgtaatcc accctatttc aaggtggatc cttattctaa tctgaacgag agtgaacatt
    17761 atctcttggc tcgacacgaa atcacgacta atttggaaga aatctgtcat agtgcccaga
    17821 gtattctcaa gtctaatggg cgtttggcca tggttcatcg tcctgatcga cttctggata
    17881 ttttggatac gttaaaacga cataatctag cccctaagcg cctgcagttt gtttatccaa
    17941 aaagagaaaa ggaagccaat atgcttttga ttgaggcgat caaggatggc tcaacaagtg
    18001 gctttaaggt cttacctcct ttgattgtcc acaatgatga tggctcttat acgcccgaaa
    18061 tcgaagagat ttattatgga tcataaggct tatatgtacg ttctggagtg tcgtgatgga
    18121 tcctactata taggctatac gactgatatg agaagacgcc tcgctatcca caatagtggg
    18181 aagggagcca aatatacacg agcacgcttg ccagtcaaac ttatctatgc tcaaggtttt
    18241 gccagtaagg aagaagccat gtcggctgaa gctcttctca agcgtaagaa gaggccacag
    18301 aaggaagaat ttttatctga aaatcaagat agaaatttac tcagttattt tgaagaatcg
    18361 tggggagtcc tttgactcct cttacctttg tcaaaaagcg aaaaaaatgc tacaataaag
    18421 aaaataaaca aaatgaggta ttatcatgtc caagattcta gtatttggtc accaaaatcc
    18481 agactcagat gccatcggat catctgtagc ttttgcctac cttgcaaaag aagcttacgg
    18541 tttggatacg gaagctgttg cccttggaac tccaaatgaa gaaacagcct ttgtcttgaa
    18601 ctattttggt gtggaagcac cacgtgttat cacttctgcc aaagcagagg gggcagagca
    18661 agttatcttg actgaccaca atgaattcca acaatctgta tcagatatcg ctgaagtaga
    18721 agtttacggt gttgtagacc accaccgtgt ggctaacttt gaaactgcaa gcccacttta
    18781 catgcgtttg gagccagttg gatcagcgtc ttcaatcgtt taccgtatgt tcaaagaaca
    18841 tggtgtagct gtgcctaaag agattgcagg tttgatgctt tcaggtttga tttcagatac
    18901 ccttcttttg aaatcaccaa caacacaccc aacagataaa atcattgctc ctgaattggc
    18961 tgaattggct ggtgtgaact tggaagaata tggtttggca atgttgaaag ctggtaccaa
    19021 cttggctagc aaatctgctg aagaattgat tgacatcgat gctaagactt ttgaactcaa
    19081 cggaaataat gtccgtgttg cccaagtgaa cacagttgac atcgctgaag ttttggaacg
    19141 ccaagcagaa attgaagctg caatgcaagc tgccaacgaa tcaaacggct actctgactt
    19201 tgtcttgatg attacagata tcgtcaactc aaactcagaa atattggctc ttggtgccaa
    19261 tatggacaag gtcgaagcgg ctttcaattt caaacttgaa aacaatcatg ccttccttgc
    19321 tggtgccgtt tcacgtaaga aacaagtggt acctcaatta actgaaagct ttaatgcgta
    19381 agattttggg tgtcagctca aaatcggaaa gtctagtttg ccttatatcg aaaggagttt
    19441 cggctccttt ttttctagga gtgaagtatg ttagaaaatg gcgatttgat ttttgtgaga
    19501 gatgggtcag acatgggaca ggccatccag acttccacag gtaactatag ccatgttgcc
    19561 atttatttgg atgggatgat ttatcatgct agtggacagg ctggtgttgt ctgtcaagaa
    19621 ccggcagact tctttgagtc caatcatttg tacgacctct atgtttaccc agaaatggat
    19681 atccagtcgg tgaaggaaag agcttgcaga catcttggag caccctacaa tgcttctttc
    19741 tatccagatg cagctggttt ctactgctcc cagtatatag cagaaatcct acctattttt
    19801 gaaactattc ctatgaaatt tggagatgag gaacaggaga ttagtgattt ttggagggag
    19861 tattacatag aactaggtct gcctgttcct ctgaaccaag ctgggaccaa tcctagtcag
    19921 ttggcagcat cgcctctgtt acaatgtaaa gaaaggaatc ttcatgattc agatttttaa
    19981 tccatctcgt ttgacgagac agccattttt ggagaattga tccgctatct ggaccagtat
    20041 gaggatgtga ttctacggga aattaaggct caatttccag atgttgcagt tgataaactc
    20101 atggaagagt atataaaggc aagcttgatt ctacgtgaaa ataagcgcta ttaccttaat
    20161 tttcctacgc ttgaatcact tgatagtctt gaactggatc aagagatttt tgtcagagaa
    20221 gctagtccgg tctatcaagc cttgttggag cagagttttg agacggaatt gcgcaatcaa
    20281 atcaatgcag ctattttagt tgaaaagacg gactttgcgc gcattaaaat gaccctgtcc
    20341 aattattttt acaaggtcaa acagcagtat cctttgacag aaaaacagca ggagctctat
    20401 gacattttag gagatgttaa tcctgagtat gccctcaagt atatgacggc ttttttgttg
    20461 aaatttctca aaaaagacca gcttatgcag aaatgccgtg atatctttgt ggacagtttg
    20521 gttgtcttag gctatattgt gcaaaatgaa gatggaaagt atgagttggc tatcgatttt
    20581 gataaggaga gattaacttt ctacttagcg tgatttcttg tttctgagta cattgtttga
    20641 ctttccttag tattcggtat aaactatatg taaccggtaa cacatatcgg aataaactaa
    20701 aggagacaat catatgtcac ttgaaaacaa attggaacaa gcaacaggcg ctgtcaaaga
    20761 aggttttggt aaagttactg gagacagcaa gacagaactt gaaggagctg ttgaaaaaac
    20821 agttgctaag gcaaaagacg ttgtagaaga cgcaaaaggt gctgtagaag gtttgaaaaa
    20881 cgtttttact aaataatagg aaaaaatcaa gggtttcatt ttcccttgat tttttctatt
    20941 cttataaata attttctgcg acggctgtat ctcctgggta ggattctttc ttgccctgga
    21001 tgatttggta acaatcgact cccttacccg caataataac tgcatctaat tcgtgatttg
    21061 tgatagccat tgccgccttg atggcttctt ggcgatccgc aatcttttca acaggatgat
    21121 tgatgtagct actaatttca tctgcaatgg ccattgggtc ttcatagtta gggtcatcag
    21181 cagtcagaaa gacttgaatc tcagggtgtt gattgaggag gaggccaaag tccttacgac
    21241 gactttctcc cttgtttcct gttgatccca gaaccagagc aatctttccg gtttgatgag
    21301 tttccaccac attgatgagt tttttcagac tatccccatt gtgggcatag tcgatgaaga
    21361 ccttggctcc atttttctga gtgaggactt ccatacgacc aggaacgcgg gttgcagcga
    21421 tgcctttttt gatgtcctca agacttgctc cgagacggag acaagcaagt ccagcagcaa
    21481 ctgcattttc ttggttgaag ttgccaatga gttggatatc ataatctcca gcgagtttac
    21541 ccgtagctga aaagctaaag gctttggaat tctcgatttg gttatcaaat tggctaccat
    21601 agaaatcatg gtcttgatct tcaacctgtt ctttcaagac tgagaagtgg tccatgtcac
    21661 tgttaatgat gactgctcgg ctattttcca tcaagagacg cttgtggtag aaatagtctt
    21721 caaagctagg gtgttcaatc gggccgatat ggtctgggct gatattgagg aaaactccca
    21781 catcaaaggt tagaccatag acacgtttga ccagatagga ttgactggag acttccatga
    21841 tgaggtgggt acggtcattt tgcacagcct gattcatcat gtcaaagagg tcaatactct
    21901 caggggttgt caacgctgac ttaaagaaag tctcgccatc aagagttgtg ttcatggtcg
    21961 acaacatagc aggtctatgc ccttgagata agatgttata ggcgaaatag gttgctgttg
    22021 tcttaccctt agtaccagta aaggcaagga gtttgagttt ctcttgtgga ttaccataga
    22081 actccatggc aatcaaactc atggctttct ttatatcgtt cacaatgatg acagggatat
    22141 cgacttcgta gtccttttca gctacatacc aagctaaacc ttgtgttata gcagaaagaa
    22201 ggtattcttt tttaaaggca gcgccttttg caaaaaaaag agtgtcttct gttacttttc
    22261 ggctgtcgta gctgatgcta tcaaaaacaa ctttgctgta gttgtagtgg taatgacctt
    22321 ggtcaataat ttcgcgaaaa aggccatctt tctttaaaat atctaatacg gtttcaatct
    22381 taatcatact ttctattgta aaccgaaagt cgcaaattta caagtaacaa ggaaaagttt
    22441 ataatggaag ataaggagtt tttcctagtt atcaaaattg aatgaggaat ctatgtcgca
    22501 cgaaaacaat caccagcagg cccagatgtt acgggggact gcttggctaa cggctagtaa
    22561 ctttatcagt cgcctactcg gggctgttta cattatccct tggtacatct ggatgggggc
    22621 ttatgcagct aaggcaaatg gtctctttac catgggttac aatatctatg cttggttctt
    22681 gttggtttca acagcgggga ttccagttgc ggtggccaag caagttgcca agtataatac
    22741 catgcgagaa gaagagcata gctttgccct gattcggagc ttcttaggct ttatgacagg
    22801 actaggcctg gtttttgctt tagtcttgta tgtctttgct ccttggctag cagacttgtc
    22861 tggcgtgggc aaagacttga tcccaatcat gcaaagcttg gcttggggag tcttgatttt
    22921 cccgtctatg agtgttatcc gaggattttt ccaagggatg aataacctca aaccctatgc
    22981 catgagccaa attgctgagc aggtcattcg tgttatctgg atgctcctag caacctttat
    23041 cattatgaag ctcggttcag gagattatct agcagccgtt acccaatcaa cctttgctgc
    23101 ctttgtcggt atggtagcca gttttgcagt cttgatttat ttccttgccc aagaaggttc
    23161 actcaaaaga gtctttgaaa caggagataa gattaacagt aagcgtctct tggttgatac
    23221 cattaaggaa gccattcctt ttatcctgac agggtctgcc atccagctct tccagatttt
    23281 ggatcagctg acctttatca atagtatgag ctggtttacc aactacagca atgaggactt
    23341 ggttgtcatg ttttcttatt tctcagccaa tcctaataaa atcacgatga ttttgatttc
    23401 tgtaggggtt tcgattggga gtgttggttt gccacttttg acggaaaact atgtcaaggg
    23461 ggacttgaaa gcagcttctc gtctggttca ggacagtctc accctactct ttatgttctt
    23521 gctaccagca acggttggag tggttatggt aggagaacct ctttatacgg tcttctatgg
    23581 taagccagat agtttggctc tgggcttatt tgtctttgca gttttgcagt ctattatttt
    23641 aggcttgtac atggtcttgt ctccaatgct tcaggccatg ttccgcaacc gcaaggccgt
    23701 tctctatttt atctatggtt ctattgccaa gctagtcttg caactaccta ccatcgccct
    23761 cttccacagt tatggtcctt tgatttcaac aaccattgct ctcatcattc ctaacgtctt
    23821 gatgtatcgg gatatttgta aagtaactgg tgtcaagcgc aaggtgattt tgaagcgaac
    23881 cattttaatc agtttgctga ccctagtcat gtttctgtta ataggaacca tccagtggct
    23941 gttaggattt ttcttccaac caagtggacg tttgtggagc ttcttttatg tagctcttgt
    24001 cggtgccatg gggggtggac tttatatggt tatgagtctg cgtacctatt tattagataa
    24061 ggtaatagga aaagcccaag cagatcgcct gcgagcaaaa tttaagcttt cgtaaggtag
    24121 catttataaa taaaaggaat aagttgaaca atcttttagg agaacttgaa acttattcct
    24181 tttttagcgt aaaaatagct aaaattatct ttcaaaaata gaaaatgagg tttttttcga
    24241 ttttttggaa aaataattga ctaaacaaac caaacgttgt ataataaaac aaatatttaa
    24301 agcaggaggt tctggaaatg aaaaagtcta agagcaaata tctaaccttg gcaggtcttg
    24361 tcctgggtac aggagtttta ttgagcgcgt gtggaaattc tagcacggcg tcaaaaacct
    24421 acaactatgt ttattcaagt gatccatcta gcttgaacta tctagcagaa aaccgcgcag
    24481 caacatccga tattgttgca aatttggtag acgggttatt agaaaatgac caatatggga
    24541 atattattcc atcattagca gaggattgga ctgtttctca ggacggtttg acctatacct
    24601 acaaacttcg taaggatgcc aagtggttta cttctgaggg agaagaatat gcgcctgtaa
    24661 ctgcccagga ttttgtgaca ggtttgcaat atgcagctga taaaaaatca gaagccttgt
    24721 atctagtgca ggactctgtt gctggtttgg atgactatat cactggtaaa acaagcgact
    24781 tttcaactgt cggtgtcaag gcacttgatg accaaacggt tcaatatact ttggttaaac
    24841 cagaacttta ctggaattca aaaacacttg caacgatact ttttcctgtt aatgcagatt
    24901 tcctgaaatc aaaaggggat gattttggga aggcggatcc atctagtatt ttgtacaatg
    24961 gacctttctt gatgaaagca cttgtctcaa aatctgctat tgaatataag aaaaacccta
    25021 attactggga tgctaagaat gtctttgtag acgatgtgaa attgacctac tatgatggta
    25081 gcgatcaaga atcactggaa cgtaatttta cagctggtgc ttatactacg gctcgtcttt
    25141 ttcctaacag ctccagctat gaagggatta aagaaaaata caaaaacaat atcatctata
    25201 gtatgcaaaa ttcaacttca tatttcttta attttaacct agataggaag tcttacaatt
    25261 atacttctaa aacaagtgac attgaaaaga aatcgactca ggaagcagtt ctcaataaaa
    25321 acttccgtca ggctatcaat tttgcttttg acagaacatc ttatggggct cagtctgaag
    25381 ggaaagaagg tgcaacaaag attttgcgta acctagtggt tcctccaaac tttgtcagta
    25441 tcaagggaaa agactttggt gaagttgtag cctctaagat ggtcaactat ggtaaggaat
    25501 ggcaaggtat caactttgcg gatggtcaag acccttacta caatcctgag aaagccaagg
    25561 ctaagtttgc ggaagctaag aaagaactcg aagcaaaggg tgttcaattc ccaatccact
    25621 tggataagac tgtggaagta acagataaag taggcataca aggagttagt tctatcaaac
    25681 aatcaattga atctgtttta ggttctgata atgtagtgat tgacattcag caattaacat
    25741 cagatgagtt tgacagttca ggctactttg ctcaaacagc tgctcagaaa gactatgatt
    25801 tatatcatgg cggttgggga cctgattatc aagacccgtc aacctatctc gatattttta
    25861 atactaatag tggaggagtt ctacaaaatc ttggactaga gcctggagaa gccaatgaca
    25921 aggctaagga agttgggctg gatgtctata ctcaaatgtt ggaagaagct aataaagagc
    25981 aagatccagc caaacgttat gagaaatatg ctgatattca agcttggttg attgatagtt
    26041 ctttagttct tccaagtgtt tcgcgtgggg gaacaccatc attgagaaga accgtaccat
    26101 ttgctgctgc ctatggttta accggtacaa aaggggttga atcatataaa tacctcaaag
    26161 tacaagataa gattgtcaca acagacgaat atgcaaaagc cagagaaaaa tggttgaaag
    26221 aaaaagaaga atccaataaa aaagcccaag aagaattggc aaaacatgtc aaataaaatc
    26281 taattgtaga taagtttgtg taagaagtct ttgtgcttaa aaacgcataa tatcaggtat
    26341 ataaaatcct agatgttatg cgttttgtta taggaagatt tattagattt tatcctcaaa
    26401 ttgagttatt cccgacttta tccgttgaaa tattataagg agtatttatg aaattaaaat
    26461 tattaagagt agatactaag gtgattatgg ggagtttctt ccttgttctg tctagtctac
    26521 ttgctttgtt gcttcccctt atcttaaaag gtttaataga tgggagttct attgaaaata
    26581 taggttccaa agtatttcaa tcgtttttga tttttattgg tcaagccttg ttttcttcta
    26641 ttggttacta tctgtttagt caatcgggtg aaaaaagata gcaaaaatca ggaaaaaagt
    26701 gatagagggg ttgatttatg cagagaaatc cttctttgat aagagccaaa gtggggagtt
    26761 gacttctgcc attgtcaatg acacgagtgt cattcgtgag tttttaatta cgactttccc
    26821 aaatattatt ctgagtttag ttatggtact tggttccatt gtagtcttat ttagtcttga
    26881 ttggaatctt tctctacttt tattcatcac tcttccttgt atgatgttta ttatcttgcc
    26941 cctttccaat atcagtgaaa agtatagtcg tcgtttacag gaggaaatcg gatttttaac
    27001 agggcaattg actgaaaaga ttcaagaaca tgaattaatt aagactaacc aagcagagaa
    27061 aagtgtacag gatgttttgg ataattgtat tgaaagggta caaaacaatt cactgaaatc
    27121 agataggatt acttcttttg agaccccgtt tgctctctta tttatctttg cgactatagc
    27181 tgtgatgcta acctatgggg gttatcgggt cagcgcagga tatatatctg tgggaacctt
    27241 ggtttcgttt ttgatttacc tctttcaatt acttaatcct attagtaata tagctaattt
    27301 tgtaactgtt tattctagga gcaagggatc ttcagttgca ctggagaact tgcttgcagt
    27361 tcctaaagaa aaatttgagg gaggaaaatc ggtatcagga cgagggttga attttaacca
    27421 tgtctatttt ggttatgatg aaaatcgacc tgtcttaaag gatattattt gttcaatttt
    27481 caaggggcaa aaaattgctt ttgttggacc atctggatca ggaaaatcaa cgattgtgcg
    27541 tttgttagag cggttttata aaccgctttc aggagatatt ctaatggagc aatcaagtat
    27601 atatgatttt aacttaaaag aatggagaag taaaatcgct tgggtttcac aaaataatgc
    27661 agtcttatct ggcagtattc gtgacaatct ttgtctcggt ttgaatcgct tagtaactga
    27721 tgatgaattg atgaaagtgc tagacttagt atcactaggt gatgagattc gctccatgaa
    27781 agagggacta gatactgaag ttggtgaacg cggacgactc ttgtcagggg ggcaaagcca
    27841 aagacttcaa atagctagag cctacttaaa agatgctgaa attcttatat ttgatgaagc
    27901 cactgctaat cttgatgcgg attctgagta tgcgattatc agtagcctct attctgtatt
    27961 aaaggagaag acggttgtga ttatagcgca tcgtttgtca acggtaaaag atgtggattg
    28021 tattttcttc ttagaggagg ggaaaatcac tggctcagga actcataagg aactactgga
    28081 aaatcatgag cgttatgctc gttttgtgca ggagcaaatg atagagtgaa ggtgtctttt
    28141 gagattcacc attttatagt ctattaaagg gagcaggaaa aactcccttt ttatatagtt
    28201 tgaaactata actagctctt gaaaacaaga aaacgaagga tacaaaataa gtggtacaat
    28261 agttactata gatttggagg aattgtatga gcaaggaatt acacattaac acaattttag
    28321 cacaagcagg gatcaagtct gatgaggcaa caggtgcttt ggtgacacca cttcattttt
    28381 caacgaccta tcagcatcca gagtttggtc gatctactgg gtttgactat acgcgcacta
    28441 aaaatccaac tcgtagtaag gctgaggaag tcttggcggc tattgagtca gcagactatg
    28501 ccctagcgac tagctcaggg atgtcagcta ttgtactggc ctttagcgtc tttccagtag
    28561 gaagtaaggt cttggcagtg cgtgatcttt acggtggttc ttttcgctgg tttaaccaag
    28621 tggagcagga aggtcatttc cattttacct atgccaatac agaagaagag ttgattgccg
    28681 agttagaaaa ggatgtggat gttctctata tcgaaacccc aaccaatccc ttgatgttgg
    28741 aatttgatat cgaaaaacta gcaaaattgg ctcatgctaa gggttccaaa gtggtggtgg
    28801 acaatacctt ctatagccct atttaccaac gtccgattga agatggagca gatatcgttc
    28861 tccattcagc aaccaagtat ctagcaggcc acaatgatgt cttggctgga gtggttgtga
    28921 ccaatagttt agaactatac gagaagcttt tttacaatct taatacaaca ggggcagtct
    28981 tgtctccatt tgacagctac cagttgcttc gtggtctcaa gaccttgtct cttcgtatgg
    29041 agcgctcaac agctaacgcc caagaagtgg ttgccttttt gaaggattct ccagcagtta
    29101 aggaagttct ctacactggt cgtggaggca tgatttcctt taaagtagcc gatgaaacac
    29161 gcattcctca tattttgaac agtctcaagg tcttctcttt tgcggaaagt ttgggcggag
    29221 tggaaagtct tattacttat ccaacgactc aaactcatgc tgatattcca gcagaagtac
    29281 gccattctta tggtttgaca gatgacctct tgcgtttgtc tattgggatt gaggatgcta
    29341 gagatttgat tgcagatttg cgccaagcct tagaaggata agacaaagat gggaaaatat
    29401 gattttacaa gcctgcccaa ccgtttaggg caccatacct ataaatggaa agaaacagaa
    29461 acggatagtg aagttctacc agcttggata gcggatatgg actttgtggt cttgcctgaa
    29521 atccgccaag ccgtgcaaac ttacgcagac caactggttt atggttatac ctatgccagt
    29581 gaagacttaa ttaaggaagt tcaaaagtgg gaagctacac aatacggtta caactttgac
    29641 aaagaggctc ttgtctttat cgagggtgtg gtaccagcca tctcaacagc tattcaaacc
    29701 tttacaaaag aaggcgaggc ggttttaatt aacacgcctg tctacccacc ctttgctcgc
    29761 agtgtcaagt tgaataatcg tagattgatt actaattcct tagtggaaaa ggatagtctg
    29821 tttgagattg actttgacca acttgaaaag gatttggtgg aagaggaggt taaactctat
    29881 gttctttgca accctcacaa tcctggtgga cgtgtttggg aaaaagaagt gttggagaag
    29941 attggccaac tctgccaaaa acacggtgtt ttgttagttt cggatgagat tcaccaagat
    30001 ttgaccctct ttggtcacaa acaccagtct ttcaatacca tcaatcctgc cttcaaaaat
    30061 tttgctatcg tcttgagcag tgccactaaa acatttaata ttgctggaac aaaaaattcc
    30121 tatgcagtca ttgaaaatcc taagttgaga ctggctttcc agaaacgcct gttggccaat
    30181 aatcagcatg aaatttcagg cttgggttat ttggcgacag aagctgccta tcgatacggt
    30241 aaagattggc tagaggaact caagcaagtc tttgaagacc acatcaatta tgtggtggat
    30301 ctatttggaa aagagactaa aatcaaggtc atgaaaccgc aaggtaccta cttgatttgg
    30361 cttgactttt cagcctatga cctgactgat gaaacattgc aagagttgtt gagaaatgaa
    30421 gccaaggtta tcctcaaccg tggtttggat tttggagagg aaggaagtct ccatgcccgc
    30481 atcaatatag ctatgcccaa atctctgttg caagaagtct gtcagcggat tgtggctact
    30541 tttgccaaat gttaaaaatc cagccttcta ggagaaaagt cttcctagaa ggctattttc
    30601 ataggcgaaa atatggtata ataaaaagat aaggtaaagg tgaaaatatg gctaaattga
    30661 ttccggggaa aattcgtatc gaaggtgttg ccctttatga aactggtaag gttgatatca
    30721 tcaaggaaaa gaacaatcgg ctctacgctc gcgttgcaga agaagaactg cgctatagtt
    30781 tagaggatga tttggttttt tgtgcctgtg atttttttca aaagaggggc tactgtgtgc
    30841 atttggcagc gctagagcat tttctgaaaa atgatgagcg tggtcaggaa atcttgtgga
    30901 gtctggaaga aggtcatgaa gaaaaagagg ccgttgaaac caaggtgacc ttgggtggca
    30961 agtttttgga tcgaatttta tctccaaaat cagaatgcgc ctatgagtta tcagctgtgg
    31021 gtcaggtgga agcaggaacc aatcatatct tgtggactct gagaatcggc caaatcaata
    31081 gccaaaaata ctatgtcatt cgggatattc cacttttttt aaggattgtc gagcagagaa
    31141 agtcgtatat gattggcaag atttatgagg agtctctttc ttgggaagcc tttgatgatg
    31201 ccagccaaga acttttgact ttcttgcacg gactaacgga ggaagggctg gttccagacc
    31261 tctttttcca aaaccaaggt cggcacctct ttttccctct gacctttttt gagcagggtg
    31321 tgaatttact gatggccttg ccccattttc aatttgacca tcaagtggat agctaccaaa
    31381 ccctgctttt tcaggatatg catgctgatg ccaatctatt tgcctttaca gtaacagaat
    31441 attcggacta ttttgaaatg gaaatcagtg agagtcctag ggtcaatgtc ttttatcaag
    31501 gagcagtact tttccataaa ggtcaggttt attttttaac agaccagcag atgcgtcttc
    31561 tcaaggaaat taaagcgtta cctgtggatc gacaaggaaa gaaatacctg caatttgata
    31621 gcagtgatcg agacaaattg gcctcctgtc tgactctttt tatccagatg ggcaccgttt
    31681 cagctccaga acgtctacaa atcaaaactt ttgcgccctc tttttacttt gacagggaag
    31741 aagataatcg gattcgttta gaaattcagt ttgattatgg aaatagacag gtatctagcc
    31801 gacaagagct agaagaatta ccattttcaa gtgacgcgga cttagaagaa agaattttcc
    31861 aagtctgttt ggctgcgggc tttgaagccg attttcaatc ttggcgtcag gccttaaaag
    31921 cggagtctgt ctatcatttt tttcatgata tcattccagt ctttgaaaaa ctcgggcatg
    31981 ttgacctatc agataaacta gaagagcttt atagcctagc gagtcctcag gtgcagattg
    32041 cctccaaggg aggtctcttg gaaatccagt ttgattttca agatattgcc caggaggaaa
    32101 tcgaccaagc catacaggcc ttggttgcca atcaggattt ttatattgat tcgtctaatc
    32161 aagtttactt tttcgatgaa gaaaccaaga aaattcgcca aaatctacag gaactggggc
    32221 aatttgaatt aaaagatggg accttgcagg ctcggaaatc cttagcctac agtttagctc
    32281 atctctttga agggcgagac cgtgtttctt tttcacaaga attccagaat ctggcccagg
    32341 atttgacaca tccagaggac tttcctttgc aagcaactca ggtcaagact gacttgcgag
    32401 attatcagga aaagggaatt ggctggttgc agatgctcca tcattatggt tttggtggga
    32461 ttttggctga tgatatggga cttgggaaaa cccttcagac cattgctttt ttgactagtc
    32521 aagtgacaaa agaaagtcga gtcttgattc tcgctccgtc gggtttgatt tacaactggg
    32581 cggatgagtt tcagaaattt gctccacagt tggatgtggc tgttgttcat ggtttgaaag
    32641 caagtcgtga ggagattctt gccgataacc atcaaatcta tgtgactagc tatgccacct
    32701 tccgtcagga cagtgagctt tatcagggga tggcctttga cttccttttc ttagatgaag
    32761 ctcaggtcat gaaaaatgcc cagaccaaga ttgcccagac cttgagacaa tttgtggtgc
    32821 cgtcggtctt tgccttgtca ggaactccga ttgaaaacca tctgggtgag ttgtggtcta
    32881 ttttccaaat cgtcatgccc ggacttttgc caagcaagaa agaatttatg aaattgccag
    32941 cagagcgagt ggctcagttt atcaagcctt tcgtgatgcg acgcaagaaa gaagaagttc
    33001 tgactgaatt gccagacttg attgaggtga tttataaaaa tgaactggaa gaccagcaaa
    33061 aggctattta ccttgcccag ttacaacaga tgcgagacca tctggctcaa gtgtcagaac
    33121 aggaatttca gcgaagtcgt gtggaaattt tatctggttt gatgcgcttg cgtcaaatat
    33181 gtgacactcc tgccctgttt atggaagatt atcagggagc cagcggcaaa ctagatagtc
    33241 tccgagacct actggtacag gtggcagacg gcggacaccg tgtcttgatt ttctctcagt
    33301 tcaagggaat gttggaaaaa attgaacaag aactgccaga cttgggcctg acttccttta
    33361 aaattacggg ttcaacccca gccaaggaaa gacaagacat gaccaaggcc tttaaccaag
    33421 gagaaagaga tgcctttctg atttccctca aggctggtgg ggtcggtctg aacctgacag
    33481 gtgcagatac agtgatcttg gttgaccttt ggtggaatcc tgcggtggaa gcgcaagcca
    33541 ttggccgtgc ccatcggatg ggtcaggaag aaacggttga ggtctatcgc ttggtgacca
    33601 agggaaccat tgaagaaaaa attcaggaac tccaagaaca aaagaaacat ctggtgtcac
    33661 aagtattgga cggcacagag tcacgtggta gtctgaccct agcagaaatt agagaaattt
    33721 tgggaatttc tgaagccagc acttgaaaaa tcaagacaat acgctataat gaagtgttga
    33781 aaggaaatag aaaatgaaac aagaacgatt tccattggtg tcagatgacg aggtcatgtt
    33841 gactgaaatg ccagtcatga atctctatga tgagtctgat ctgatcagta atatcaaggg
    33901 tgagtatcga gataaaaatt atttagaatg ggctcctatt gctgaagaaa aaccagtaaa
    33961 accgattgaa aagcaagtag ggaaacctaa aaaagctcct ttaggggtta aaaaagaagg
    34021 aaagagctat gcggaggtgg cgcgtgaaga agcgcgtgca gacttgaaaa agaaacgctc
    34081 tgctaactat ctaactcagg atttcagcct tgcgagacgt cattctcagc ccagtctagt
    34141 tagacagggc aatcaaccga caactccttt ccaaaaggaa aatcctggtg aatttgtcaa
    34201 atatagccaa aaattgaccc agtctcatta tatcttggcg gaagaagttc attctatccc
    34261 taccaagaat gaagaagtgt cagcacctgc tccaaagaaa aacaattatg attttctaaa
    34321 gaagagccaa atctacaata aaaaaagtaa acaaacagaa caagaacgtc gggttgccca
    34381 agagttgaat ctgaccagaa tgacagaata ggggagaaaa catgtcaaag acatatcatt
    34441 ttatcggaat taagggatca gggatgagtg ccttggcctt gatgttgtac cagatggggc
    34501 acaaggttca gggatcagat gttgaaaagt actactttac ccaacgcggt cttgagcagg
    34561 caggaattac cattcttcct tttgatgaaa agaatctaga cggtgatatg gaaattatcg
    34621 ctggaaatgc ctttcgtcca gataacaacg tcgaaattgc ctatgcggac caaaatggta
    34681 tcagctacaa acgttaccat gagtttctag gtagctttat gcgtgacttt gttagcatgg
    34741 gagtagcagg agcacatgga aaaacttcaa cgacaggtat gttgtctcat gtcttgtctc
    34801 acattacaga taccagcttc ttgattggag atgggacagg tcgtggttcg gccaatgcca
    34861 aatattttgt ctttgaatct gacgaatatg agcgtcactt catgccttac cacccagaat
    34921 actctattat caccaacatt gactttgacc atccagatta tttcacaagt ctcgaggatg
    34981 ttttcaatgc ctttaacgac tatgccaaac aaatcaccaa gggtcttttt gtctatggtg
    35041 aagatgctga attgcgtaag attacgtctg atgcaccaat ttattattat ggttttgaag
    35101 ctgaaggcaa tgactttgta gctagtgatc ttcttcgttc aacaactggt tcaaccttca
    35161 ccgttcattt ccgtggacaa aacttggggc aattccacat tccaaccttt ggtcgtcaca
    35221 atatcatgaa tgcgacagcc gttattggtc ttctttacac agcaggattt gatttgaact
    35281 tggtgcgtga gcacttgaaa acattttccg gtgttaaacg tcgtttcact gagaaaattg
    35341 tcaatgatac agtgattatc gatgactttg cccatcatcc aacagaaatt attgcgacct
    35401 tggatgcggc tcgtcagaaa tacccaagca aggaaattgt agcagtcttt caaccgcata
    35461 cctttacaag aaccattgcc ttgttggacg actttgccca tgctttaaac caagcagatg
    35521 ctgtttatct agcgcaaatt tatggctcgg ctcgtgaagt agatcatggt gacgttaagg
    35581 tagaagacct agccaacaaa atcaacaaaa aacaccaagt gattactgtt gaaaatgttt
    35641 ctccactcct agaccatgac aatgctgttt acgtctttat gggagcagga gacatccaaa
    35701 cctatgaata ctcatttgag cgtctcttgt ctaacttgac aagcaatgtt caataggatg
    35761 ttcccatgga aattccaatt aagatcattc aggcaagcaa gtctgatttg cctgagatag
    35821 gggcacttca gacctcgtct tttccagctg aaaagcagca actttcccat attttagaag
    35881 aaagtatccg taagtgtgcg gatacctttc ttctagctag ggatgaaaat caacttttag
    35941 gctatatttt atcaagtccc cagtcagaca atccgcaata tctaaaagta cattctttag
    36001 tcatcgagtc tgaccatcag agacagggct tgggaacact tcttcttgca gccttgaaag
    36061 aggtggcagt tgagctggat tacaaaggga ttcgtttgga gagtcctgat gagctgcttt
    36121 cctattttga aatgaacggt tttgttgatg aagaagcaac tttgctctat gcaactagcc
    36181 agggctatag tatgatttgg tttaatccct tttatctgga ggaacaatga aaatcagaca
    36241 agcaagatta gaagatttgg atcggattgt tgaacttgaa tttgaaaatt tttcggtcga
    36301 agaagccatt cctccttctg tctttgaagc acatttgaga gaaattcaga cctcttttct
    36361 ggttgctgaa aaagaaggaa gaatcatggg ttatatcgaa ggaccagttg gcctgcaccg
    36421 ccatctgcaa gaccagtctt ttacagaaga aataaaagac tatagtcatg agcctggtgg
    36481 ttatatctct gtgacctgtc tgtctattgc caaggaggca cagggactcg gactgggtca
    36541 gaaattgctg acagccttga aagaagttgc tcttgaagat gagagagatg gcattaatct
    36601 aacctgtcat gactatctca tcgcctacta tgaaaaacat ggatttgtca acgaaggcca
    36661 gtcccagtca acctttgcag gggaaacatg gtatgatatg gtctgggaaa tgaaaaaata
    36721 agttaggaaa agtatcatag attgcttttt ttggactttt aagatataat attatggatt
    36781 atcaacaagg aggaaaaact tttgagtgaa aagtcaagag aagaagagaa attaagcttt
    36841 aaagagcaga ttctgagaga tttagaaaaa gtaaaaggct atgatgaagt tctgaaagaa
    36901 gatgaggcag tagttcgcac tcctgcaaat gaaccttcaa ctgaagaact catggctgat
    36961 tccttgtcaa cggtagagga gattatgaga aaagctccta ccgtgcctac tcacccaagt
    37021 caaggtgtac cagcttctcc agcagatgag attcaaagag aaactcctgg tgttccaagt
    37081 catccaagtc aagatgtacc ttcttctcca gcggaagaaa gtggatcaag accaggtcca
    37141 ggtcctgtta gacctaagaa acttgaaaga gaatacaatg aaaccccaac aagggtagct
    37201 gtttcctata cgacggcaga gaaaaaagca gaacaagcag gtccagaaac acctacgcct
    37261 gctacagaaa cagtggatat catcagagat acatcacgtc gtagccgtag agaaggagca
    37321 aaacccgtta agcctaagaa agagaagaag tcacatgtga aagcttttgt gatttcattc
    37381 cttgtattcc ttgccttgct ctcagcaggt ggttactttg gttaccagta cgtgctagat
    37441 tccttattac ctatcgatgc taattctaag aaatatgtga cggttggaat tccagaaggt
    37501 tcaaacgttc aagaaatcgg tacgacgctt gaaaaagctg gtttggtaaa gcatggtctg
    37561 atttttagtt tttatgccaa gtataaaaat tataccgact tgaaagcagg ttactacaat
    37621 ttgcaaaaga gtatgagtac agaagactta ctcaaagagt tgcaaaaagg tggaacagat
    37681 gaaccgcaag aacctgtact tgcgactttg acaattccag aaggttatac cttggatcag
    37741 attgctcaag ctgtgggtca attgcaaggt gacttcaaag agtctttgac agcggagact
    37801 ttcttggcta aagttcaaga tgagacgttt atcagtcaag cagtagcgaa atatcctact
    37861 ttactggaaa gtttgcctgt aaaagacagc ggtgcgcgtt atcgtttgga aggatacctt
    37921 ttcccagcta catactctat caaggaaagc acaactattg agagcttgat tgatgagatg
    37981 ttagctgcta tggataagaa cctatctcct tactatagta ctatcaaatc taaaaacttg
    38041 actgtcaatg agttgttgac cattgcttcc ttggtcgaaa aagaaggtgc caagacagaa
    38101 gatcgtaagc tcattgcagg tgtattctac aatcgtttga atcgtgatat gccacttcaa
    38161 agtaatattg caatcttgta tgcccaagga aaactggggc aaaatatcag tctagctgag
    38221 gatgttgcga ttgataccaa cattgattca ccttataatg tttataaaaa tgtaggtctc
    38281 atgcctggtc cagtcgatag tccaagtctg gatgcgattg agtcaagcat caatcaaact
    38341 aagagcgata acctctactt tgtagcagat gtcacagaag gcaaggtcta ctatgctaac
    38401 aatcaagaag accacgaccg caatgtcgct gaacatgtca acagcaaatt aaactaaaca
    38461 aactaaaatt atgttatact tcacataatt ttctttagaa aatattatca gaagaaagtt
    38521 gagaaaaatg gcagaaaaaa catatcctat gacccttgag gaaaaggaaa aacttgaaaa
    38581 agaattagaa gaattgaaat tggttcgtcg accagaagtg gtagaacgca ttaagattgc
    38641 ccgttcatac ggtgaccttt cagaaaacag tgagtacgaa gcagctaagg atgaacaagc
    38701 ctttgtcgaa ggacaaatct ctagcttaga aacaaaaatc cgctatgctg aaatcgtcaa
    38761 tagcgacgca gttgcccagg acgaagtagc gattggtaaa acagtcacca tccaagaaat
    38821 tggtgaggac gaagaagaag tttatattat cgtaggttca gctggtgcgg atgcctttgc
    38881 aggtaaggtt tcaaatgaaa gcccaattgg gcaggccttg attggcaaga aaacaggtga
    38941 tacagcaacc attgaaacgc ctgttggtag ctatgatgta aaaatcttga aggttgaaaa
    39001 aacagcctaa aaacagaaaa aggagtgggg aggcgatgtg cttcactcac tcctttttcc
    39061 attttgctat tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttgc cgtatgtatg
    39121 gttactgact tcgtcagttt catctacaac ctcaaaacca tgttttgagc cgacttcgtc
    39181 agtttcatct acaacctcaa aaccatgctt tgagctgact tcgtcagttt catctacaac
    39241 ctcaaaacca tgctttgagc tgacttcgtc agtttcatct acaacctcaa aaccatgctt
    39301 tgagctgact tcgtcagttc tatctacaac ctcaaaacag tgttttgagc aacctgcggc
    39361 tagtttccta gtttgctctt tgatttttat tgagtattag atgtatagtg cattgaagtt
    39421 aaaatagtac actttgattt ctaagacatt gttagaaatt agattaaatt ccttaatcga
    39481 tttgcgcatg ttttatttca tttcactata ctttagattg gaaaataagg aatcacataa
    39541 atcgcaagaa atagggaatc tgattcgtgt ttataaccgt tcaaaaagag aagaggctga
    39601 aagtgagcca cttaatcttt atgtcgaaga tgaaaagggc aatctcctgg caggtttgat
    39661 agcagagact tttggaaatt ggctagaaat cgagtatttg tttgtaaaag aggaactgcg
    39721 agggcaagga atcggttcaa aactattgca acaggcagaa agtgaagcta agaatcgaaa
    39781 ttgttgtttt gcctttgtca atacttacca gttccaggca ccggactttt atcagaaaca
    39841 tggctacaag gaagtttttt ctttgcaaga ctatctctac attaggcaaa gatattatta
    39901 ccaaaagaat ctgtaaggtg agtatggagg tataatacaa agagaggctc gcacataagt
    39961 atggaggtgg actgatgtat atgagtaact atcgataaat accagttata acctagaaat
    40021 tgtgtctttc tagacgatat tgaggacaat ataatcgtag ccccaaaatt aggaatcaag
    40081 acttatcagg ttaagaaaag aagtgatgtt gttgatattt taaacaattt atttaaacta
    40141 aaaactctct atctattaat ccgagattcc cctctcggat tttgtgttgc tttcattaaa
    40201 tttacaggta agacttgcta gcttcagtaa atatacacaa gtttttcaga atagagtgaa
    40261 atccaaaaga aaatggaaat aatgaaagct cttgtaggca taagaaaaca cctctgtgtt
    40321 atacttgttg ttcaaccaca aacacaagaa aggcacagag atgcaagaca attatactac
    40381 aaaagccaaa catttgacaa tcgatagccg tcgcttaatc gaaagatgga aaaaagaagg
    40441 gaaatcaaat agagaaattg cctctctgct tggaaaagtt cctcaaacta tccacactga
    40501 aatcaagcgt gggacagtcc gacaatgtct tggaaaaggg cgcttcaaag aggtttattc
    40561 tgccgactat gctcaacagt cttatgaaaa taatcgcaag cgctcggtca agaaatcaag
    40621 cttgaccaag gaactaaagg aaaagattct ccactatcat aaccaaaaat tttcgcctga
    40681 aatgatggtg atggctaaag gggttaacgt gggaatttca accatttact attggattca
    40741 tcatggaaaa ttggggttaa gcaaacagga tctgctttac cctagaaaag gaaaagcgct
    40801 taagaaacag gctagcacca actttaaacc tgctggtcaa tccatcgaac agcggtctga
    40861 agctatcaat cttcgcttgg agaatgggca ttatgagatt gatacggttc tacttacgag
    40921 agcgaaaaac tactgcttgc ttgtcttgac ggatcgaaag agtagacatc agatcatccg
    40981 attgattcca aataaaagtg ctgaggtggt caatcaggct ctaaaactca tcttaaaaca
    41041 acacaagatt ctttccatca cggcagataa tggaacggaa ttcaatcgct tgtttgatgt
    41101 attttctgag gagcacatct attatgcgca cccctatgcc tcttgggaaa ggggaactaa
    41161 tgagaatcac aacaggctca ttcgtagatg gttacctaag ggaaccaaga aaatgactcc
    41221 caaagaagtc gcattcatcg aaaagtggat taacaactat cctaaaaaat gcttggacta
    41281 caagtcaccc agagaagact tctggatggc taacttgaac ttgaaattta gcaaaatgga
    41341 aataattttt attaaacgct tccaatagcg gttaaaagtt gacaaattta aattttagga
    41401 ctacactaag taagtaaatt ttattttaaa ggagaatttg ttatgaattt aacattttta
    41461 ggcttatgta ttgcctgtat gggcgtatct gtcggtgaag gtttattgat gaatggactg
    41521 tttaaatcag tagcacgcca accagatatg ctttctgagt ttcgtagttt gatgttttta
    41581 ggtgttgcct ttattgaagg aactttcttt gtaactcttg tcttctcatt tattatcaaa
    41641 taaatacatg gaacgagaag aaaagggagg attttagatg gaagaaagta ttaatccaat
    41701 catctctatt ggtcctgtta tcttcaatct gactatgtta gccatgactt tgttgattgt
    41761 gggagttatt tttgtcttta tttattgggc aagccgcaat atgaccttga aacccaaagg
    41821 aaagcaaaat gtacttgagt atgtctatga ctttgttatt ggatttacag aacctaacat
    41881 tggttcgcgc tacatgaaag attactcact ctttttcctt tgtttattcc ttttcatggt
    41941 gattgccaat aaccttggct taatgacaaa gcttcaaacg atcgatggga ctaactggtg
    42001 gagttcgcca accgctaatt tacagtatga cttaacctta tcttttcttg tcattttgtt
    42061 gacacatata gaaagcgttc gtcgtcgtgg atttaaaaaa agtataaaat cttttatgag
    42121 tcctgttttt gtcataccga tgaatatctt ggaagaattt acaaacttct tatctttggc
    42181 tttgcggatt tttgggaata tctttgcagg agaggtcatg acgagtttgt tacttcttct
    42241 ttcccaccaa gctatttatt ggtatccagt agcctttgga gctaatttgg cttggactgc
    42301 attttctgtc tttatttcct gcatccaagc ttatgttttt actcttttga catctgtgta
    42361 tttagggaat aagattaata ttgaagagga atagaaagga gtaactgatg cacgtaacag
    42421 taggtgaatt aattggtaat tttattttaa tcactggctc ttttattctt ttgctagtct
    42481 tgattaaaaa atttgcatgg tctaatatta caggcatttt cgaagaaaga gctgaaaaaa
    42541 ttgcttcaga tattgacaga gctgaagaag cccgtcaaaa agcagaagta ttggctcaaa
    42601 aacgcgaaga tgaattggct ggtagccgta aagaagctaa gacaatcatt gaaaatgcaa
    42661 aggaaacagc tgagcaaagt aaggctaata tcttagcaga tgctaaacta gaagcaggac
    42721 acttaaaaga aaaagccaat caagaaattg ctcaaaataa agtagaagct ttacagagtg
    42781 ttaagggtga ggtcgcagat ttgaccatca gcttagctgg taaaatcatc tcacaaaacc
    42841 ttgacagtca tgcccataaa gcactcattg atcagtatat cgatcagcta ggagaagctt
    42901 aatggacaag aaaacagtaa aggtaattga aaaatacagc atgccttttg tccaattggt
    42961 acttgaaaaa ggagaagaag accgtatctt ttcagacttg actcaaatca agcaagttgt
    43021 tgaaaaaaca ggtctgcctt cttttttaaa acaagtggca gtagacgagt cggataagga
    43081 aaaaacaatt gcttttttcc aagattctgt gtcgccttta ttacaaaact ttatccaggt
    43141 tctggcctac aatcacagag caaatctttt ttatgatgtg cttgtagatt gcttgaaccg
    43201 acttgaaaaa gaaacaaatc gatttgaagt gacgattacg tctgctcatc ctctaactga
    43261 tgaacagaag actcgtttgc tccctttgat tgagaaaaaa atgtctctga aagtaaggag
    43321 tgtaaaagaa caaatcgatg aaagtctcat tggtggtttt gtcatttttg ccaatcacaa
    43381 gacaattgat gtgagtatta aacaacaact taaagttgtt aaagaaaatt tgaaatagaa
    43441 agtggtgttc ttttggcaat taacgcacaa gaaatcagcg ctttaattaa gcaacaaatt
    43501 gaaaatttca aacccaattt tgatgtgact gaaacaggtg ttgtaaccta tatcggggac
    43561 ggtatcgcgc gtgctcatgg ccttgaaaat gtcatgagtg gagagttgtt gaattttgaa
    43621 aacggctctt atggtatggc tcaaaacttg gagtcaacag acgttggtat tatcatccta
    43681 ggtgacttta cagatatccg tgaaggcgat acaatccgcc gtacagggaa aatcatggaa
    43741 gtccctgtag gtgaaagtct gattggtcgt gttgtggatc cgcttggtcg tccagttgac
    43801 ggtcttggag aaatccacac tgataaaact cgtccagtag aagcaccagc tcctggtgtt
    43861 atgcaacgta agtctgtttc agaaccattg caaactggtt tgaaagctat tgacgccctt
    43921 gtaccgattg gtcgtggtca acgtgagttg attatcggtg accgtcagac agggaaaaca
    43981 accattgcga ttgatacaat cttgaaccaa aaagatcaag atatgatctg tatctacgtc
    44041 gcgattggac aaaaagaatc aacagttcgt acgcaagtag aaacacttcg tcagtacggt
    44101 gccttggact acacaatcgt tgtgacagcc tctgcttcac aaccatctcc attgctcttc
    44161 ctagctcctt atactggggt tgctatggcg gaagaattta tgtatcaagg taagcatgtt
    44221 ttgattgtat acgatgatct atcaaaacaa gcggtagctt atcgtgaact atcgctcttg
    44281 cttcgtcgtc ctccaggtcg tgaagccttc ccaggggatg ttttctatct ccacagccgt
    44341 ttgcttgagc gctcagctaa agtttctgat gaacttggtg gtggatcaat tacagcccta
    44401 ccatttatcg agacacaagc aggagatatc tcagcctata tcgcaaccaa cgtgatttct
    44461 atcactgatg gacaaatctt ccttggcgat ggcctcttca atgcaggtat tcgtccagcc
    44521 atcgatgcgg gttcatctgt atctcgtgta ggtggttctg cacaaatcaa agccatgaag
    44581 aaggttgctg gtacacttcg tatcgacctt gcttcatacc gtgagttgga agcctttact
    44641 aagtttggtt ctgacttgga cgcagcaaca caggctaagt tgaaccgtgg acgtcgtacc
    44701 gttgaggtct tgaaacaacc tgttcacaaa ccattacctg ttgagaaaca agtaaccatt
    44761 ctttatgctt tgacacatgg tttcttggat actgttccag tagatgatat tgttcgtttc
    44821 gaggaagagt tccatgcctt ctttgatgct caacatccag agattttgga aaccattcgt
    44881 gatacaaaag acttgccaga agaagcagtc ttggatgctg cgattacaga gtttctcaat
    44941 caatctagct tccaataaga atagaggtgt cagatggcag tgtctctaaa tgatattaaa
    45001 acaaaaatcg cctcaacaaa aaatacgagt caaatcacta atgccatgca aatggtatcg
    45061 gctgctaagt taggtcgctc tgaagaagct gctcgcaact tccaagttta cgctcagaaa
    45121 gtgcgtaaac ttttgacaga tatccttcat ggtaatggag ctggtgcttc aactaatccg
    45181 atgttgatta gccgttctgt gaagaagaca ggctatatcg ttatcacttc agaccgcggt
    45241 ttggttggag gttataattc ctctattttg aaagctgtta tggagttgaa agaagaatac
    45301 cacccagacg gtaaaggttt tgaaatgatc tgtatcggtg ggatgggagc tgatttcttt
    45361 aaggctcgcg gtattcaacc actttatgaa ttacgtggct tggcagacca acctagcttt
    45421 gatcaagttc gtaagattat ttcaaaaact gttgaaatgt accaaaatga actctttgat
    45481 gagctttatg tttgctacaa ccaccatgtc aatacgctaa ccagtcaaat gcgtgtggaa
    45541 caaatgcttc cgattgttga cttggatcca aatgaagcgg atgaagagta cagcttgact
    45601 tttgaattgg aaaccagccg agaagaaatt ctggagcagt tgttgcctca gtttgcagaa
    45661 agtatgattt acggtgccat tatcgatgcc aagacagctg agaatgctgc gggtatgaca
    45721 gccatgcaaa cagcgacaga taatgctaag aaagtcatca atgatttgac aattcagtat
    45781 aaccgtgcca gacaggcggc gattacacaa gaaattacag aaatcgtagc aggtgctagt
    45841 gccttagaat aggctctagt ccagctcgta tgaaaatgaa cttaggacct agttgagcta
    45901 ggaaccgaca gtatcttata tagaatagga gaaggagatg agttcaggta aaattgctca
    45961 ggttatcggt cccgttgtag acgttttgtt tgcagcaggg gaaaaacttc ctgagattaa
    46021 caatgcactt gtcgtctaca aaaatgacga aagaaaaaca aaaatcgtcc ttgaagtagc
    46081 cttggagtta ggagatggta tggttcgtac tatcgccatg gaatcaacag atgggttgac
    46141 tcgtggaatg gaagtattgg acacaggtcg tccaatctct gtaccagtag gtaaagaaac
    46201 tttgggacgt gtcttcaacg ttttgggaga taccattgat ttggaagctc cttttacaga
    46261 agacgcagag cgtcagccaa ttcataaaaa agctccaact tttgatgagt tgtctacctc
    46321 ttctgaaatc cttgaaacag ggatcaaggt tattgacctt cttgcccctt accttaaagg
    46381 tggtaaagtt ggacttttcg gtggtgccgg agttggtaaa accgtcttaa tccaagaatt
    46441 gattcacaac attgcccaag agcacggtgg tatttcagta tttactggtg ttggggaacg
    46501 tactcgtgag gggaatgacc tttactggga aatgaaagaa tcaggcgtta tcgagaaaac
    46561 agccatggtc tttggtcaga tgaatgagcc accaggagca cgtatgcgtg ttgcccttac
    46621 tggtttgaca atcgctgaat acttccgtga tgtggaaggc caagacgtgc ttctctttat
    46681 cgataatatc ttccgtttca ctcaggctgg ttcagaagta tctgcccttt tgggtcgtat
    46741 gccatcagcc gttggttacc aaccaacact tgctacggaa atgggtcaat tgcaagaacg
    46801 tatcacatca accaagaagg gttctgtaac ctctatccag gctatctatg tgccagcgga
    46861 tgactatact gacccagcgc cagcaacagc cttcgctcac ttggattcaa caacaaactt
    46921 ggaacgtaaa ttggtacaat tgggtatcta cccagccgtt gacccacttg cttcaagctc
    46981 acgtgccttg gcacctgaaa tcgttggaga agagcactat gcagttgctg ctgaagtaaa
    47041 acgtgtcctt caacgttacc atgaattgca agatatcatt gctatccttg gtatggatga
    47101 gctttctgat gaagaaaaga ccttggttgc tcgcgcccgt cgtatccagt tcttcttgtc
    47161 acaaaacttc aacgttgcgg aacaatttac tggtcagcca ggttcttatg ttccagttgc
    47221 tgaaactgta cgtggcttta aggaaatcct tgatggtaaa tacgaccact tgccagaaga
    47281 tgccttccgt ggtgtaggtt ctatcgaaga tgtgattgca aaagctgaaa aaatgggatt
    47341 ttaagaggtg acctatggct cagttaactg tccagatcgt gacaccagat ggtctcgtct
    47401 atgatcacca tgccagctat gtatcggttc gaactctgga tggtgagatg gggatcttgc
    47461 cacgacatga aaatatgatt gcggttttag cagttgatga agtaaaggta aaacgtatcg
    47521 atgataaaga tcacgtgaac tggattgcag taaacggtgg cgttattgaa attgccaatg
    47581 atatgatcac aatcgtcgct gactctgcag aacgtgctcg tgatatcgat attagccgtg
    47641 cagaacgtgc caaacttcgt gcagaacgtg caattgaaga agcacaagac aaacatttga
    47701 ttgaccaaga acgtcgtgct aagattgctt tgcaacgtgc cattaaccgt attaatgtcg
    47761 gaaatagact ataagaaaaa atgaacttga aaataccaag ttcatttttt aggctctttg
    47821 tcaactgtag tgggttgaaa aaaagctaag ctcgagaaag gacaaatttt gtcctttctt
    47881 ttttgatatt cagagcgata aaaatccgtt ttttgaagtt ttcaaagttc cgaaaaccaa
    47941 aggcattgcg cttgataagt ttgatgagat tattggtcgc ttccaatttg gcgtttgaat
    48001 agggtagttg aagggcgttg acgattttct ctttgtcctt tagaaaggtt ttaaagacag
    48061 tctgaaaaag aggatgaacc tgcttaagat tgtcctcaat aagtccgaaa aatttctctg
    48121 gttccttatt ctgaaagtga aacagcaaga gttgatagag ctgatagtga tgtttcaagt
    48181 cttgtgaata gctcaaaagc ttgtctaaaa tctctttatt ggttaaatgc atacgaaaag
    48241 tagggcgata aaaatgttta tcgctgagtt tacg
//
LOCUS       DAVLCS010000011        45329 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLCS010000011 DAVLCS010000000
VERSION     DAVLCS010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.011"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            53..829
                     /locus_tag="VXC78_000738"
     CDS             53..829
                     /locus_tag="VXC78_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582854.1"
                     /translation="MRTNILKLSQFLNIFYLKIALLIFSCLYFIAPWFIVLKDFETYK
                     VQYPAVIGIAEFIVLTSFLVFVYISPIFFVIFLYKIIVGSINVRRCLIKIKNYKFYMI
                     VLNRIPLHTFMVYFSSVLLWIMYLTKPVDVSNALPLPIILPLEKINPFYMILGYWLLN
                     KRCEYQLHQYLYPVMRGSSHDGRIYALPEELFIWNRNRSQKIGKWKRDRRYNTTTDLV
                     EAQIGYSKFPFFLLATKWSVDPYDQNWTIGEKAYLTSRWK"
     gene            1005..2393
                     /locus_tag="VXC78_000739"
     CDS             1005..2393
                     /locus_tag="VXC78_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0582855.1"
                     /translation="MKSKTVLVTSLAAVTFGLVSLVDTAGALPFSAKTVQADTQTLTT
                     AAKYYILVPKDSEVFKNWRGTANRPIIWATKTTPELSYFQESARNYIANENKSGANYI
                     EWKGTVEEFKEAIKNLTDKKLTPNPAPIPQSDKKPTPDPTPNPQSTVPSGWSGSSYYQ
                     NGTKVTSKWIFDKNYNSYFYLDASGNYVQNAWEGDYYLKSGGYMAKKEWIYDKNYGAY
                     YYLTPDGYYARNTWVGNYYLKSNGKMAKSEWIYDKNYSSYYYLTSEGSYARNTWVGDY
                     YLKSNGKMAKGEWIYDNNYSSYYYLTSEGSYARNTWVGDYYLKSNGKMAVSERTPDGY
                     QVDGSGKWISSEGTHTASSSQATSLGISLYNVNDAMTYIDIALPSTPSSSYQVAYDFA
                     LVDANTGSVSTQTQFTVTYNPSLRVFQTRHFFSATPDGSYRFVIKGKGQDGKVYDGQS
                     VVFRVKNHRFVG"
     gene            2452..3468
                     /locus_tag="VXC78_000740"
     CDS             2452..3468
                     /locus_tag="VXC78_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0582856.1"
                     /translation="MNKKKLLVCAVALSTVGVVSTIDTAGVLPFSAQTVHAEITRTEN
                     HEVKSKITPGSENGSIYVDMTVENVPVHYHVYIYADIVNAKTGQIPRKDTFNERFDRS
                     SVPITKQGWTNFANVPDGEYYLQFHGEDDYRSVLYKFIGKSATFTVKDQKYVNPLDSS
                     TPKETEKPTATETSKPATNSSSGQTGWSGSSYYKAGVKVVNQWIFDVQYNSYFYLNAS
                     GNFVQNAWSGSYYLKSGGYMAKSEWIYDNNYQSYYYLTAEGSYARNAWSGSYYLKSDG
                     KMAKSEWIYDSSYQSYYYLTSEGSYARNTWVGDYYLKSDGKMAVNERTPDGYKVDGSG
                     KWVR"
     gene            3609..5171
                     /locus_tag="VXC78_000741"
     CDS             3609..5171
                     /locus_tag="VXC78_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582857.1"
                     /translation="MKKFLLATTLLLTLVLGGCQYLPWNKSAETPSDSTSETSVATPE
                     IDYSSYNKVLDDYEKVAKGTLPTGMDVNPLASQVKSSQGFYTDVVYHKTDLNNDGVDE
                     LLLALEMKSGEKSLLDIRTLKDEKVIRLTNQENRLDQIGERMTVGILPDNSLLYRGAG
                     TATSHIYAHYQFSEDGQSLIKDKEAQELADLGVGSPISLETLSWKSVSDKLPGGSSAD
                     KGKPSVDYSPYNSILKDYEFILDYKSEVKDNINPTANIYAGMAERSQAFTYAMVDMDK
                     NGIDELIVSSKNGSEILDIFTLKDQKVIRLTNAENKMQMLGTRFKAYLLENGNLYTQW
                     NPFAGDPQTIHTIWKLNSSGDKLEKVKEAKTEDEVSPGTRMNLSSLTWKSVTEKFAAT
                     ASSTSKTASGKMDINAIKNGDFSSIEGRWSNGHGGEDLVFSKDGLIAPEKFKVDLTES
                     EFVNGFLRARYSAPDFGIFIQFVPAGVRIPDGTSRGELVTDASDISKDRIIFHAAFPL
                     HGDPRQFLYRVE"
     regulatory      5375..5463
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            5554..6876
                     /locus_tag="VXC78_000742"
     CDS             5554..6876
                     /locus_tag="VXC78_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV0582858.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVVLLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     gene            7094..7642
                     /locus_tag="VXC78_000743"
     CDS             7094..7642
                     /locus_tag="VXC78_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV0582859.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            7752..8651
                     /locus_tag="VXC78_000744"
     CDS             7752..8651
                     /locus_tag="VXC78_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV0582860.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEMAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(8676..9950)
                     /gene="serS"
                     /locus_tag="VXC78_000745"
     CDS             complement(8676..9950)
                     /gene="serS"
                     /locus_tag="VXC78_000745"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV0582861.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(10164..10535)
                     /locus_tag="VXC78_000746"
     CDS             complement(10164..10535)
                     /locus_tag="VXC78_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV0582862.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            complement(10538..11902)
                     /locus_tag="VXC78_000747"
     CDS             complement(10538..11902)
                     /locus_tag="VXC78_000747"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV0582863.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLTAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            12227..13012
                     /locus_tag="VXC78_000748"
     CDS             12227..13012
                     /locus_tag="VXC78_000748"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV0582864.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            13106..13540
                     /locus_tag="VXC78_000749"
     CDS             13106..13540
                     /locus_tag="VXC78_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0582865.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            13540..14514
                     /locus_tag="VXC78_000750"
     CDS             13540..14514
                     /locus_tag="VXC78_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV0582866.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            14575..14799
                     /locus_tag="VXC78_000751"
     CDS             14575..14799
                     /locus_tag="VXC78_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0582867.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            14918..15892
                     /gene="fabK"
                     /locus_tag="VXC78_000752"
     CDS             14918..15892
                     /gene="fabK"
                     /locus_tag="VXC78_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV0582868.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            15885..16805
                     /gene="fabD"
                     /locus_tag="VXC78_000753"
     CDS             15885..16805
                     /gene="fabD"
                     /locus_tag="VXC78_000753"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV0582869.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEATPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCSLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            16839..17570
                     /gene="fabG"
                     /locus_tag="VXC78_000754"
     CDS             16839..17570
                     /gene="fabG"
                     /locus_tag="VXC78_000754"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV0582870.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGTFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            17592..18827
                     /gene="fabF"
                     /locus_tag="VXC78_000755"
     CDS             17592..18827
                     /gene="fabF"
                     /locus_tag="VXC78_000755"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV0582871.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEILYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            18830..19315
                     /locus_tag="VXC78_000756"
     CDS             18830..19315
                     /locus_tag="VXC78_000756"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV0582872.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            19312..19734
                     /gene="fabZ"
                     /locus_tag="VXC78_000757"
     CDS             19312..19734
                     /gene="fabZ"
                     /locus_tag="VXC78_000757"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV0582873.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            19746..21113
                     /gene="accC"
                     /locus_tag="VXC78_000758"
     CDS             19746..21113
                     /gene="accC"
                     /locus_tag="VXC78_000758"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV0582874.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            21150..22016
                     /locus_tag="VXC78_000759"
     CDS             21150..22016
                     /locus_tag="VXC78_000759"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV0582875.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            22013..22780
                     /locus_tag="VXC78_000760"
     CDS             22013..22780
                     /locus_tag="VXC78_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV0582876.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKSLEELLEERYQRFRKY"
     gene            22938..23122
                     /gene="briC"
                     /locus_tag="VXC78_000761"
                     /pseudo
     CDS             22938..23122
                     /gene="briC"
                     /locus_tag="VXC78_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
     gene            23140..23589
                     /locus_tag="VXC78_000762"
     CDS             23140..23589
                     /locus_tag="VXC78_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582877.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIELYVTIILGLGADVYSL
                     ILTMVLVGSFLLLIWRLKKKKSWNWSFVFSLFATYVVYQILGNFWARYAHLINHRNIH
                     DEYFTVVLSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            23611..23839
                     /locus_tag="VXC78_000763"
                     /pseudo
     CDS             23611..23839
                     /locus_tag="VXC78_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(23888..24310)
                     /gene="nusB"
                     /locus_tag="VXC78_000764"
     CDS             complement(23888..24310)
                     /gene="nusB"
                     /locus_tag="VXC78_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV0582878.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(24303..24692)
                     /locus_tag="VXC78_000765"
     CDS             complement(24303..24692)
                     /locus_tag="VXC78_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0582879.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            complement(24714..25274)
                     /gene="efp"
                     /locus_tag="VXC78_000766"
     CDS             complement(24714..25274)
                     /gene="efp"
                     /locus_tag="VXC78_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV0582880.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            complement(25403..26845)
                     /gene="gatB"
                     /locus_tag="VXC78_000767"
     CDS             complement(25403..26845)
                     /gene="gatB"
                     /locus_tag="VXC78_000767"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV0582881.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            complement(26845..28311)
                     /gene="gatA"
                     /locus_tag="VXC78_000768"
     CDS             complement(26845..28311)
                     /gene="gatA"
                     /locus_tag="VXC78_000768"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV0582882.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            complement(28311..28613)
                     /gene="gatC"
                     /locus_tag="VXC78_000769"
     CDS             complement(28311..28613)
                     /gene="gatC"
                     /locus_tag="VXC78_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV0582883.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            28826..30370
                     /locus_tag="VXC78_000770"
     CDS             28826..30370
                     /locus_tag="VXC78_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV0582884.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            30812..31297
                     /locus_tag="VXC78_000771"
     CDS             30812..31297
                     /locus_tag="VXC78_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV0582885.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENITQDL
                     I"
     gene            31413..31601
                     /locus_tag="VXC78_000772"
     CDS             31413..31601
                     /locus_tag="VXC78_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV0582886.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            31758..32123
                     /locus_tag="VXC78_000773"
     CDS             31758..32123
                     /locus_tag="VXC78_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0582887.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            32126..33793
                     /locus_tag="VXC78_000774"
     CDS             32126..33793
                     /locus_tag="VXC78_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV0582888.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMSAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            33993..35693
                     /locus_tag="VXC78_000775"
     CDS             33993..35693
                     /locus_tag="VXC78_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV0582889.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            35686..36162
                     /gene="ilvN"
                     /locus_tag="VXC78_000776"
     CDS             35686..36162
                     /gene="ilvN"
                     /locus_tag="VXC78_000776"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV0582890.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            36228..37250
                     /gene="ilvC"
                     /locus_tag="VXC78_000777"
     CDS             36228..37250
                     /gene="ilvC"
                     /locus_tag="VXC78_000777"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0582891.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVTEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            37357..37593
                     /locus_tag="VXC78_000778"
     CDS             37357..37593
                     /locus_tag="VXC78_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582892.1"
                     /translation="MLADQNKADWSYDENTVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSSFERAGATKSARYIAKWILRNKKH"
     gene            37831..38187
                     /locus_tag="VXC78_000779"
     CDS             37831..38187
                     /locus_tag="VXC78_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0582893.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            38237..39487
                     /gene="ilvA"
                     /locus_tag="VXC78_000780"
     CDS             38237..39487
                     /gene="ilvA"
                     /locus_tag="VXC78_000780"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV0582894.1"
                     /translation="MLSSKDIIKAHKILNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            40371..40586
                     /locus_tag="VXC78_000781"
     CDS             40371..40586
                     /locus_tag="VXC78_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582895.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(40695..41435)
                     /locus_tag="VXC78_000782"
     CDS             complement(40695..41435)
                     /locus_tag="VXC78_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0582896.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(41435..43000)
                     /locus_tag="VXC78_000783"
     CDS             complement(41435..43000)
                     /locus_tag="VXC78_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0582897.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            43138..45027
                     /locus_tag="VXC78_000784"
     CDS             43138..45027
                     /locus_tag="VXC78_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV0582898.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
BASE COUNT        13350 a         8307 c        10266 g        13406 t
ORIGIN      
        1 atcatggttt taagaaatga taaattggat ggataggaga gcaggaagtt atatgagaac
       61 aaacatttta aaattaagtc aattcttgaa tattttctat ttaaaaattg ctttactaat
      121 attctcgtgc ttgtatttta tcgctccatg gttcattgta ttaaaggatt ttgaaacata
      181 taaagttcaa tatccagctg ttattggaat agctgagttt atcgttttaa catctttttt
      241 agtttttgta tatatttcac caatcttctt tgtgattttt ctatataaaa taattgtggg
      301 cagtattaat gtaagacgct gtttgataaa gataaagaat tacaaattct atatgattgt
      361 tttgaataga ataccactac atacatttat ggtttatttt tcatcagtat tgttatggat
      421 aatgtatctt acaaaaccag tggatgtgag taatgcttta cctttgccaa ttatcttacc
      481 tcttgaaaag ataaatccct tctatatgat tctaggatat tggctcttaa ataagcgatg
      541 tgaatatcag ttgcatcagt acctttatcc tgtaatgaga gggagttctc atgacggtag
      601 aatttatgca ctaccagagg aactttttat ctggaatagg aatagaagtc aaaaaattgg
      661 taagtggaaa cgagatagaa ggtacaatac gaccaccgat ctagtcgaag ctcaaattgg
      721 ttatagtaag tttccgtttt ttttgctagc aacaaaatgg tcagtggatc cttatgatca
      781 aaattggaca ataggagaaa aggcatattt gacaagtagg tggaaatgat aaaatagaaa
      841 gtctttagtc taataactag gaaaaagatt aagtatactt ttttcataaa aatttcattt
      901 gctaatcaaa taaagtataa acacagatac tcttttcata aatatagtag agtccatccc
      961 ttactgtaag cctaaataat aaaaatttaa aggaggtttt gataatgaag tcaaaaacag
     1021 ttttagtaac cagcctagcc gctgtaacat ttggtcttgt gtctcttgta gatacagcag
     1081 gagctctacc tttttcagca aaaacggtac aagctgacac acaaacgctg actacagctg
     1141 caaaatatta tattcttgtt ccgaaggatt cagaagtatt taaaaattgg agaggtactg
     1201 ctaatcgtcc cattatttgg gccacaaaaa ccactccaga attatcttat ttccaagaat
     1261 ctgctcgcaa ctatattgct aatgagaata agtctggtgc caattacata gagtggaagg
     1321 gaactgtaga agagtttaaa gaggcgatta agaatctgac ggataaaaaa ctaactccaa
     1381 atccagctcc aatcccacaa tcggataaaa aaccaacccc agatccaact ccaaatccac
     1441 aatctacagt tccgtctggt tggtcaggat catcttacta ccaaaatggt actaaagtca
     1501 ctagtaagtg gattttcgat aagaactata attcctactt ctacctagat gcttcaggta
     1561 attatgttca aaatgcatgg gagggtgatt actatcttaa gtcaggtggc tacatggcta
     1621 agaaggagtg gatctatgat aagaactatg gagcttatta ttacttaact ccagatggct
     1681 actatgctcg caatacttgg gtgggcaact attatctcaa gtcaaacggt aagatggcta
     1741 aaagcgagtg gatctatgat aagaactaca gttcatatta ctacctaacg tcggaaggaa
     1801 gttacgcccg taatacttgg gtaggtgatt attatctcaa gtcaaatgga aagatggcta
     1861 aaggtgagtg gatttatgac aataactaca gctcttacta ttacttaaca tcggaaggaa
     1921 gttatgctcg taatacatgg gtaggtgatt attatctcaa gtcaaatgga aagatggcag
     1981 ttagcgaacg tacaccagat ggctaccaag tggatggatc aggcaagtgg attagttctg
     2041 agggaactca tacagcaagc agttcacaag caacatcatt aggaataagc ctttacaatg
     2101 tcaatgatgc tatgacctat attgatatcg ctctacctag cactccatcc tcatcttatc
     2161 aagtagccta tgattttgcc ttagttgatg caaatacagg ttcagtttct acacaaaccc
     2221 agtttactgt gacctacaat ccaagcttac gtgtctttca aactcgtcac ttctttagtg
     2281 ccactccaga tggtagttat cgctttgtta tcaaaggaaa aggacaagat ggcaaggtat
     2341 acgatggcca atcagttgtc tttcgtgtaa agaatcatcg ttttgtcgga tagatgagtg
     2401 ataggtttta aacaaataaa tattaaaaat aaaataaagg aaatgaataa catgaacaaa
     2461 aagaaattat tagtatgtgc tgtggcactt tcaacagtcg gagtagtatc aacaatcgac
     2521 acagcaggag ttctcccttt ttcagcacaa acagtgcatg cggaaattac tcgtaccgag
     2581 aatcatgagg taaaatctaa gattacacca ggatcagaaa atggaagtat ctatgtggat
     2641 atgactgttg aaaatgtacc tgtacactat catgtatata tatatgcaga tattgtaaat
     2701 gcaaaaacag ggcaaattcc tagaaaagat actttcaatg aaaggttcga tagatcatct
     2761 gttccgatta caaagcaagg ttggactaat tttgcaaatg ttccagacgg tgaatattac
     2821 ttacaatttc atggagaaga cgattacaga agtgttttgt ataaatttat tggcaaatca
     2881 gcgacattca ctgttaaaga tcaaaaatat gtcaatcctc tagactcttc aactcctaaa
     2941 gaaacggaaa aaccaacagc tactgaaact tcaaaaccag ctactaactc tagctcaggt
     3001 cagactggct ggtcaggttc ttcttactac aaagctggtg tgaaagtagt caatcaatgg
     3061 atttttgatg ttcagtacaa ttcatacttc tacctcaatg cttcaggtaa ctttgttcaa
     3121 aatgcttggt ctggaagtta ctacctcaag tcaggtggct acatggctaa gagcgaatgg
     3181 atttatgaca ataactatca atcatactat tacttgacag cagagggtag ctatgcacgt
     3241 aatgcttggt ctggaagcta ctacctcaaa tcagatggta aaatggctaa gagtgagtgg
     3301 atctatgata gtagctacca atcttactat tacctaacat cagaaggaag ttacgcccgt
     3361 aatacatggg taggtgacta ctacctcaaa tcagatggta agatggcagt caacgaacgt
     3421 accccagatg gctacaaagt agacggctca ggtaagtggg ttcgctagaa tgatagcttg
     3481 tgagaaatgg cttataacaa ataaatagaa acggaaaata atttgtttat aggcaacatt
     3541 ttgatacaat aaaaatagcg aaaggaattg gcacaggctg gttcctttct cttagataaa
     3601 ggagtaatat gaaaaagttt ttattagcca caacactttt actgacacta gttctaggag
     3661 gctgtcagta tttaccttgg aacaaaagcg cagaaacacc atctgattca acatcagaaa
     3721 catctgtagc gactccagag atagactaca gttcctataa taaagttttg gatgactatg
     3781 aaaaagtagc gaaaggcacc ttgccgacag gtatggatgt caatcctctg gctagtcaag
     3841 tgaagtcttc tcaaggcttt tatacagatg tggtttacca caagacggat ttgaataatg
     3901 atggagtcga tgaactttta cttgctcttg aaatgaagag tggcgaaaag agtttacttg
     3961 atattcgtac gctgaaagac gaaaaggtga ttcgtttgac caatcaagaa aatcgtttag
     4021 accagattgg tgagagaatg acggtcggta tccttccaga caattctctg ctctatcgtg
     4081 gagctggtac agcaacgagt cacatctatg ctcactacca atttagtgaa gatgggcagt
     4141 ctttgataaa ggataaggaa gctcaagaac tagcagatct tggggtcggt tcgcccattt
     4201 ctctagagac cttaagctgg aagtcagttt cagataaact tccaggagga agcagtgcag
     4261 ataaggggaa accaagtgta gattacagtc cttataatag cattttgaag gattatgaat
     4321 ttattttaga ctataagtca gaggttaagg ataacatcaa tccaactgct aatatctatg
     4381 caggaatggc agaacgcagt caagccttta cctatgcaat ggttgatatg gacaaaaatg
     4441 gcattgatga attgattgtc tcttcgaaaa atggtagtga gattttagat atttttacac
     4501 tcaaagatca gaaagttatt cgcctcacca atgctgaaaa taaaatgcag atgcttggaa
     4561 ctcgtttcaa ggcctatcta ttagaaaatg gtaatctcta tacccagtgg aatccgttcg
     4621 caggagatcc acagaccatt cataccattt ggaaattgaa tagtagtggg gacaaactag
     4681 agaaggttaa agaagctaag acagaggatg aagtcagtcc aggtactcga atgaatctat
     4741 ctagtctgac ctggaaatct gtaacagaaa aatttgctgc aacagcatct tcaactagca
     4801 aaacagcttc agggaaaatg gatataaacg ccatcaaaaa tggagatttt tctagtattg
     4861 agggaagatg gagtaatggt catggaggag aagacttagt ctttagtaaa gatggcttga
     4921 tagcaccaga gaaatttaaa gttgacctta cagaatcaga atttgtaaat ggttttttac
     4981 gagctcgtta ttcagcacca gactttggaa tctttattca gttcgtacca gcaggtgtta
     5041 gaataccgga tgggacatct aggggtgagt tggtcacgga tgcttcggat attagtaaag
     5101 atcgaatcat cttccatgct gcatttccgc tacatggtga tccaagacaa ttcttatatc
     5161 gtgtggaata agagtgaaac agcttgattt aataactaat agcaccccac gcacatggga
     5221 atgctcaatc cttcttctac agagtcaaat aagatttttc caaaacacat tgacaaaagc
     5281 caacattttt tgtaaaataa gaatcaatta aataccaaca ccgaatgaag tttaatagaa
     5341 gtggggaatc gtttgatttt ccatgactgt aaatggacgg aactctggag agaccgtaaa
     5401 ggcaccgaag gggcaaggca ggcaactgct caaactctca ggtaaaagga cagagctagg
     5461 atagaccgct ttttagcatt tatctaagca ttccagagta catgtatctt gcatgtgctc
     5521 tttcttttgg ggttgaaacg ataggagaag gaaatgttag aattgcttaa atcaatcgat
     5581 gcttttgctt ggggaccgcc cctcttgatt ttattggtcg gaacagggat ttacctaacc
     5641 atgcggctag gactcttgca ggttttgcgt ctgcccaagg cctttcagct tatttttatc
     5701 caggataagg gacatggtga tgtatccagt tttgcagctc tgtgtacagc cttggcatca
     5761 actgttggaa caggaaatat cataggagtt gcgacggcta tcaaggttgg tggaccagga
     5821 gctctatttt ggatgtggat ggcggctttc tttggaatgg ctaccaagta tgcggaagga
     5881 ctcttggcca tcaaataccg caccaaggac gaccatggtg cagtagcggg aggtcccatg
     5941 cactatatcc ttctagggat gggagaaaag tggcgaccac ttgctgtttt gtttgcagta
     6001 gcaggagtat tggttgttct cttgggaatc ggaaccttca cccaagtcaa ctcgattgca
     6061 gaatctatcc aaaatacaac gacgatttcg ccagccatca cagctctcgt cttgtctgtc
     6121 tttgtagcga ttgcagtctt tggtggactc aagtctattt ctaaggtttc aactactgtt
     6181 gttcctttta tggccctcat ttatatctta ggaactctta cagttatttt ctttaatatc
     6241 ggaaaaatcc ctggcacaat cgctttagtc tttacctcag cttttagtcc ccttgctgcg
     6301 gtaggtggat ttgctggtgc tagcgttcgg atggctattc aaaatggtgt ggcgcgtggt
     6361 gtgttctcaa acgaatcggg tctgggttct gctcctattg cagctgcagc tgccaagaca
     6421 aatgaaccag tagagcaagg tttgatttcc atgacaggaa cctttattga taccctcatc
     6481 atttgtactc taactggttt gaccatcttg gtaactggag tttggagcgg tgacttgaat
     6541 ggggttgcct tgactcagtc agctttctca acagtctttt cacactttgg gcctgctctc
     6601 ttgaccatct tccttgtact ttttgccttt acaacgattc taggttggaa ctattacgga
     6661 gaacgctgtt ttgagttcct ctttggggtt cgctttatct ggctctaccg tgtggttttt
     6721 gtgctcatgg tcttgttagg aggatttatc gagttggata tggtctggat tatcgcagat
     6781 atcgttaacg ccttgatggc tctgccaaac ttgattgccc tcttggtctt gtcgccagtc
     6841 gttattgctg aaactaaaaa gtattttgac aaataatgga atcacacagc tcgtgtgatt
     6901 tttttgccta taaataattt ttatcagcct gatatataat atatattatg caagtgattg
     6961 gaagtgtgat aaactaatat aacaacgaaa atcttatgag agaataaagc tttatcttag
     7021 ataaacttag gaatcaggat tttataagat tttccaataa tattagtgtc aacaataaga
     7081 aaagaggtat cttatgacaa catttactat ccatacagta gagtcagcac cagcagaagt
     7141 gaaagaaatt cttgaaacag tagaaaaaga caacaatggc tatattccca acctaatcgg
     7201 tctcttggcc aatgccccga ctgttttaga agcctaccaa attgtctcat ctatccaccg
     7261 tcgcaacagc ctgacacccg ttgagcgtga agtggtgcaa atcacggcag ccgtgaccaa
     7321 tggttgtgcc ttctgtgtcg caggtcacac agccttttcc atcaaacaaa tccagatgaa
     7381 tgatgacttg attcaagctc ttcgcaatcg tactccaatt gaaacagatc ctaaattgga
     7441 taccctagct aagtttacct tggcagttat caataccaag ggtcgtgtag gagatgaagc
     7501 cttgtctgag tttttagaag ctggctacac tcaacaaaat gccttggatg tggtttttgg
     7561 tgtcagccta gcaatcctct gtaactatgc caacaactta gctaatacac caattaatcc
     7621 agaattgcaa ccttatgcct aattcatatc tgagtaaaat gaagtctgaa ataatcggac
     7681 ttcgtttttt taaatcctca tttaagcgct tttatgttat actgaaacta acatgattat
     7741 tggaggttag gatgaaaaaa ctccccttag tattttcagg ttgtttgcta ggtttggcag
     7801 gagctggaaa tcttatttta gatacgttgc cagttctatc ccatcttttt agtctgactg
     7861 gtttggtttt atggatttac tttctaattc tgcatctctt taattggaaa gaaaccaagc
     7921 aagaattgac caagccccct cttttgtcag gaatggcaac ctttcctatg gctgggatga
     7981 ttttatcgac ctatgtcttt cgcgtattct cttatcttcc tttggtagca caagggattt
     8041 ggtggttttc atttctcttg gatttgacct tgattgctgg ttttaccatc aagtttgctt
     8101 gtccagggcg gagggttcat gccactccaa gttggacggt tctctatgtg gggatagcag
     8161 tggctgcctt gacctatcct ctggtaggta ttatcgaaat ggcctatgcg accctgagtt
     8221 ttggttttct cttgaccttc tatctctatc cccttattta tagcgattta aagaaacatc
     8281 cactcccact agccttgctt ggacaagaag gaatctactg tgctcctttc tctctactct
     8341 tggcttctct agttcgagta ggaggaacca gcctgccgac ttgggtcttg attgtcatga
     8401 ttttggcttc tcaatccttc tttttctttg ttttaactcg tctgcccaac attttaaaac
     8461 aaggttttca accagccttc tcagccctca ccttcccaac cattatcaca gcgacctcgc
     8521 tcaagatggc tcagggaatt ttgaaacttc catttctgga ttacctggta ttggctgaaa
     8581 ccattatatg cctaactatt ttattctttg tactaggtgc ttatctgatt tggttacgaa
     8641 aaaaggtcta gctagaaata gctaaacctt attttttatg gtttgatgac ttcagctcca
     8701 cccatgtatg gacgaagtgc ttctgggatg gtcacagaac catcttcatt ttggtaattt
     8761 tcaagaattg cagccactgt acgtccaact gcaagtccag aaccgttcaa ggtatgaagg
     8821 agtttcacct tgccatctgc ttcatcacgg taacggattt gggcacgacg ggcttggaaa
     8881 tcttctgtgt ttgaacagct tgagatttca cggtaattgt tttgtgctgg aatccacact
     8941 tccaagtcgt aagtcttcgc agctgagaag cccatatctc cagtagagag agcaacgaca
     9001 cggtatggaa ggttgagttt ttgaagaatg ttttcagcgt tggctgtcat tttttccaat
     9061 tcttcgtaag attcttctgg tttggcaaat ttgaccattt caaccttgtg gaattggtgc
     9121 aaacggatca agccacgcgt atcacgaccg gcagaaccag cctcagaacg gaatgacgga
     9181 ctcatggcag tgaagtagat tggaagatct ttgccgtcta agatttcatc acggtagtag
     9241 tttgtcagag gaacttcagc agttggaatc aagacaaagt tggtatcgct gagttcaaaa
     9301 gtatcttcct taaattttgg atactgacca gtaccaaaca tagaatcatg gttgactatg
     9361 taaggtgtga tgacttcagt atagccttct tttccatgtt catccaacat aaagttgtag
     9421 atagcacgtt ccaaacgagc accgaggcct ttatagaaga ggaagcgagc gcctgttacc
     9481 ttaccaccgc gttcccagtc aagaatacca aggtcttcac cgagatccca gtgagcttta
     9541 ggttcgaagt caaactcgcg tggagtaccc caacggcgaa cttccacatt gtcgtcttcg
     9601 tcagccccaa caggaacgct gtcagctggg atatttggaa gagtcgttgt aaattctgtc
     9661 aatttagcat cgatttctgc caattcagca tccaaggctt taacctcagc agatagattt
     9721 tgcatggcag caatcttgtc atctgtattt tccttgttgc gcttagcttg ggcaatctca
     9781 gcagaaactg tgttacgttc tgctttgaga gtttcaacct tgaccaagat gttacgacgt
     9841 ttagcatcga tttctttcat ttcattcaag acagcagcat ctacaccacg tgtagctaat
     9901 ttttctgcga cagcttcaaa atctgtacga atacgtttga tatctaacat aagaactcct
     9961 ttatgaaaaa agcacgcctg acaaaacgtt ggagtggcag ggccacggtt ccatccaact
    10021 tcacaggtgt gcacttgatt gtgtatgtaa ttgttactaa cggtagaatt tcacctatcc
    10081 ctcctatctg ctcgcagtac ccgcagactt tctgaaagaa gaagataacc tacttatccg
    10141 ttgctatgat tatactaaag tttctacttt tttgcaaata gatttttaaa tttttggcta
    10201 attgtctgaa tcagggtcgg aagtttgacg accttgtcat tgcctagttt ttcgcgtgca
    10261 attttgagaa tggcacctga gtcttttgaa gcaaagagga attttccttt gtctgtaaag
    10321 acttcgaagt ggcggctgat tttgcgtcca gtgacattgg ctccaatctg attgatatgg
    10381 ctccaaggaa tctggataaa ttgttcgaca ttgacatctg ggtaaaattc caaagcctga
    10441 tctccgacaa ggaatttccc aactttccca gcgatagaga ggtaggaagt gcctgtcgta
    10501 ctgaggagta ctgttttgtt aagtgattgg gccatgctta gtcttcctta ctttctccaa
    10561 aaaaggcatt gtagagggct ttaattgctg ctttctcttg gtctttattg acaacaaaca
    10621 taatagaaac ttcactagaa ccttgagaca tcatctggat gttgattttg ttttcagata
    10681 gagcgcgtgt cgcagtagca gtcactccga tgtggctctt cattttttca ccaacaatca
    10741 taatgataga aaggtcgtgt tcgatttctg catgatctac tttagccttt tgaaccaact
    10801 gacgcaggat ttcttcttcc ttgatgggag ttagttggcg agaacggaga atgatagaaa
    10861 gatcgtcgat acctgttggc atatgttccc aaccgatgtt aagttcttcc aggatttgca
    10921 gaaccttgcg gccaaatcca acctcacggt tcatgaggta tttcgacatg ttaatgctga
    10981 caaagcctga gtcaccagca attcccacaa ctggaaattc atcattactg tgttttagaa
    11041 cgatacgagt acctggatgg tcagggttgt tggtattctt gataaccaga ggaatttttc
    11101 cacggtaggc aggaagaaga gcctcgtcat gaaggactga gaagcctgca taggccaact
    11161 cgcgcatttc acggtaggtc aactcaggaa tcgagtgtgg ttggtggata ataccagggt
    11221 gggctgcaaa gataccatca acgtccgtaa agttttcata gaggtcggct ttgacaccag
    11281 cagcaatgat agaacctgta atatcagaac ctccacgtga gaaagtacag atttgatttt
    11341 ccttagtgac accaaagaaa ccaggaatga caaggacttc attggtgttt gtcaattctt
    11401 caatcttgtc ataacttgat ggaatgatgc gagcgtgacc aggttcactt gtgaccacaa
    11461 tcccagcttc tctagggtgc atatagcgtg catcgatacc attttggtta aagtaggcag
    11521 cagtcaattt ggcattgtta ttttcaccgg ctgctaggaa agtatcgtag agaaattcat
    11581 tttcttcaat aggaagagtg gccaaggcgt gaatgctttt agaaattttt tctagcacag
    11641 ctggttttag tcccaattca ctaaccatag cagcatagcg gtcgataatc cagctttggc
    11701 tcttgctaat atcgttaccc gcaacatagt cgcggtagta tttaatcagg gcatccgtaa
    11761 ccttagtatc ttcagcattg cgtttaccag gcgcagaaac gactacaaaa cgacgctctg
    11821 aatcgctttt gacgatgttt aaaacttttt ctaattgact agcagaggca agagaactac
    11881 ctccaaattt aacaactttc ataagaactc ctaaagtaag tattttatac gattatagca
    11941 gaaagaaagg cttttttcaa tgaagaaaat aagatgcttt ctagcctaaa gcgagccttt
    12001 cttatcggct gagacacttt cagtcgattt tttcttgctt tctgctccta aaaaagatat
    12061 actttgacag tgaaataatt taacactcaa tgaaaatcaa agagcaaact aagaagctag
    12121 acgaagtcag ctcaaaatac tgttttgagg ttgcagatgg aagctgacgc ggtttaaaga
    12181 gattttcgaa gagtataaac tgcttataaa ataaaaagga gccctgatgg aacacattat
    12241 ttatcagctt gaagaggact tggcaatcct taccttgaac cgtcctgagg tcgcaaatgg
    12301 ttttcatatt cccatgtgtg aggagatttt agaagctctg actttggcag aagaaaatcc
    12361 agctgtgcat tttatcttaa tcaatgccaa tggaaaggtc ttctcagttg ggggagattt
    12421 ggtagagatg aagcgggcag tggatgagga tgatattcca tcattgacaa aaatcgcaga
    12481 gttggtcaat acgatttctt ataaaatcaa gcaaatagcc aaacctgttt taatggaagt
    12541 tgacggtgct gttgcaggtg ccgcagcgaa tatggctgtt gcggcagatt tctgtttggc
    12601 gacggataag gctaagttta tccaagcctt tgttggtgtt ggtttggctc cagatgcagg
    12661 gggaattcat ctcttgagcc gcagtatcgg tgtgacgcgt gctgctcaat tagctatgac
    12721 aggagaggct ttaacggcag aaaaagccct agaatggggg ttggtttacc gcgtttctga
    12781 agctgaaaaa cttgaaaaga cgagagaaca gcttcttaaa aaattaagac gtgcttcaag
    12841 taattcctat gctgccatta agaagttggt ttgggagagc cagtttaaag actggcaggg
    12901 ttacgctact ttagaactga acctacagaa atccttagct caaacagagg atttcaaaga
    12961 aggagtgcga gctcattcgg agagaagaag acctaaattt acaggaaaat aaaaaatact
    13021 tgcatcattc tttgaatttt gatataattc tttctgtcaa atgttttgat tgtaaaagtt
    13081 ttttgaagaa ggagggatat gaaaaatgga ctaccaacga atcaatgaat atttaacatc
    13141 tatatttaac aatgtccttg taattgagga agtgaacttg agaggtagtc gttttaagga
    13201 tatctccatc aaagaaatgc atacgattga tgtcatcggt aaggctccag acgtgactcc
    13261 aagtcaagtg tcaaaagagt tgatggtaac tcttggaact gttacgacaa gtttgaacaa
    13321 tttagagcgt aagggctaca ttgagcgagt tcggtcagaa caggatcgtc gtgtggtgca
    13381 tctgcatttg acaaagaagg gtcgcttgat tcataggctg cataaacgct tccacaaggc
    13441 catggtagaa aaaattattg atggcatgag cgaggaagaa attgctgtca tgggtaaagg
    13501 tttgactaat ctttaccaat ttttggagga tttgaaataa tggcttttgc aaaaataagt
    13561 caggttgctc attatgtgcc agagcaagtg gttacaaatc acgacttggc tcagattatg
    13621 gataccaatg atgagtggat ttcaagtcga acgggaatac gacaaaggca tatttcaaga
    13681 acagaatcta ccagtgattt ggctacagag gttgctaaga aactgatggc aaaagctgga
    13741 ataacaggag aagaactgga ttttatcatc ctagctacca ttactccaga ttcgatgatg
    13801 ccctctacag ctgctcgtgt tcaagctaat attggtgcta ataaagcctt tgcttttgac
    13861 ttaaccgcgg cttgcagtgg atttgtattt gctctttcaa ctgctgaaaa gtttatcgct
    13921 tctggtcgct ttcaaaaagg cttggtgatt ggtagtgaaa ccctctctaa ggcagtcgat
    13981 tggtcggatc gatcaacagc tgtgttgttt ggagatggtg ctggtggtgt cttgttagaa
    14041 gctagcgagc aagagcattt cttagctgag agtctcaata gcgatggaag tcgcagcgag
    14101 tgtttaactt atgggcattc aggtttgcat tctccatttt cagatcaaga aagtgcagat
    14161 tcgtttttga agatggatgg acgcacagtc tttgattttg ccattcgaga tgtagccaag
    14221 tctatcaagc agactattga tgaatctcct atagaggtga cagacttgga ttatctgcta
    14281 cttcatcaag ccaatgaccg tattttggat aagatggcta gaaaaattgg tgttgaccga
    14341 gccaaacttc cagccaatat gatggaatat ggcaatacca gtgcagccag tatcccgatt
    14401 ttactttcag agtgtgtaga acaaggtctc atccctttag atggtagcca gactgttctt
    14461 ctatcaggct tcggtggagg cttgacctgg ggcacgctca ttcttacaat ttaggtaatc
    14521 atgtggtgaa cacattgtta taaaaaaaac tatttatttt aaaggagtcc tatcatggca
    14581 gtatttgaaa aagtacaaga aattatcgtt gaagaacttg gaaaagacgc atcagaagta
    14641 acacttgaat caacttttga tgatttggac gcagattcat tggacttgtt ccaagtaatc
    14701 tcagaaatcg aagatgcttt tgatatccaa atcgaagcag aaaatgactt gaaaacagtt
    14761 ggtgacttgg ttgcttacgt tgaagagcaa gcaaaataag cagaatatta gtagaaggag
    14821 tagggagaaa cccactccct cttgtttagg taatagtttg actgtcaaat tatggtgaaa
    14881 tcgaactatt acgtaagcaa ggaaggttgg aggcactatg aaaacgcgta ttacagaatt
    14941 attgaagatt gactatccta ttttccaagg agggatggcc tgggttgctg atggtgattt
    15001 ggcaggggct gtttccaagg ctggaggatt aggaattatc ggtgggggaa atgccccgaa
    15061 agaagttgtc aaggccaata ttgataaaat caaatcattg actgataaac cctttggggt
    15121 caacatcatg ctcttatctc cctttgtgga agatatcgtg gatctcgtta ttgaagaagg
    15181 tgttaaagtt gtcacaacag gagcaggaaa tccaagcaag tatatggaac gtttccatga
    15241 agctgggata atcgttattc ctgtcgttcc tagtgtcgct ttagctaaac gcatggaaaa
    15301 aatcggtgca gacgctgtta ttgcagaagg aatggaagct ggggggcata tcggtaaatt
    15361 aacaaccatg accttggtgc gacaggtagc cacagctgta tctattcctg ttattgctgc
    15421 aggaggaatt gcggatggtg aaggtgctgc ggctggcttt atgctaggtg cagaggctgt
    15481 acaggtgggg acacggtttg tagttgcaaa agagtcgaat gcccatccaa actacaagga
    15541 gaaaatttta aaagcaaggg atattgacac tacgatttca gctcagcact ttggtcatgc
    15601 tgttcgtgct attaaaaatc agttgactag agattttgaa ctggctgaaa aagatgcctt
    15661 taagcaggaa gatcctgatt tagaaatctt tgaacaaatg ggagcaggtg ccctagccaa
    15721 agcagttgtt cacggtgatg tggagggtgg ctctgtcatg gcaggtcaaa tcgcagggct
    15781 tgtttctaaa gaagaaacag ctgaagaaat cctaaaagat ttgtattacg gagccgctaa
    15841 gaaaattcaa gaagaagcct ctcgctggac aggagttgta agaaatgact aaaacagcct
    15901 ttttatttgc tggtcaaggt gcccagtatc tagggatggg acgggatttc tatgatcagt
    15961 atccgattgt taaagaaacg attgatcgag cgagtcaggt gctcggttat gatttgcgtt
    16021 atctcatcga tacggaagag gacaaactca atcagacccg ctatacgcaa ccagccattc
    16081 tagcgacttc ggttgctatc taccgtttat tgcaagaaaa gggctatcag cctgatatgg
    16141 ttgctggttt gtctcttgga gaatactctg ccttggtggc aagcggcgcc ttggattttg
    16201 aagatgcggt tgccttggta gctaagcgtg gagcctatat ggaagaagcg actcctgctg
    16261 actctggcaa gatggtagca gttctcaata cgccagtaga ggtcattgaa gaagcctgtc
    16321 aaaaagcttc tgaacttgga gtggttactc cagccaacta taacacacct gcacaaatcg
    16381 tcattgctgg agaagtggtt gcagttgatc gagcggttga acttttgcaa gaagcaggtg
    16441 ccaaacgctt gattcctctt aaggtgtcag gtccctttca caccgctctc cttgagccag
    16501 ctagccagaa actagctgaa actctagctc aggtaagttt ttcagatttt acttgttccc
    16561 tagtcggcaa tacagaagct gctgtgatgc aaaaagagga cattgctcag ctcttgacgc
    16621 gtcaggtcaa ggaacccgtt cgtttctatg aaagtattgg ggtcatgcaa gaagcaggca
    16681 taagcaactt tatcgagatt ggaccgggga aagtcttgtc aggttttgtt aaaaaaattg
    16741 atcaaactgc tcacttagct catgtggaag atcaagcgag tttagtagca cttttagaaa
    16801 aatagactaa aataagtaga agttttgaaa ggaaaaaaat gaaactagaa cataaaaata
    16861 tctttattac aggttcgagt cgtggaattg gtcttgccat cgcccacaag tttgctcaag
    16921 caggagccaa cattgtctta aacagtcgtg gggcaatctc agaagaattg ctcgctgagt
    16981 tttcaaacta tggtatcaag gtggttccca tttcaggaga tgtatcagat tttgcagacg
    17041 ctaagcgtat gattgatcaa gctattgcag aactgggttc agtagatgtt ttggtcaaca
    17101 atgcagggat tacccaagat actcttatgc tcaagatgac agaagcagat tttgaaaaag
    17161 tgctcaaggt caatctgact ggtaccttta atatgacaca atcagtcttg aaaccgatga
    17221 tgaaagccag agaaggtgct atcattaata tgtctagtgt tgttggtttg atggggaata
    17281 ttggtcaagc taactatgct gcttctaagg ctggcttgat tggctttacc aagtctgtgg
    17341 cacgcgaggt cgctagtcgg aatatacgag tcaatgtgat tgctccagga atgattgagt
    17401 ctgatatgac cgctatctta tcagataaga ttaaggaagc tacactagct cagattccga
    17461 tgaaagaatt tgggcaggca gagcaggttg cagatttgac agtattttta gcaggccaag
    17521 attatctaac tggtcaagtg attgccattg atggtggctt aagtatgtag cgaaagctag
    17581 aggtgaaaag aatgaaacta aatcgagtag tggtaacagg ttatggagta acatctccaa
    17641 tcggaaatac accagaagaa ttttggaata gtttagcaac tgggaaaatc ggcattggtg
    17701 gcattacaaa atttgatcat agtgactttg atgtgcataa tgcggcagaa atccaagatt
    17761 ttccgttcga taaatacttt gtaaaaaaag ataccaaccg ttttgataac tattctttat
    17821 atgccttgta tgcagcccaa gaggctgtaa atcatgccaa tcttgatgta gaggctctta
    17881 atagggatcg ttttggtgtt atcgttgcat ctggtattgg tggaatcaag gaaattgaag
    17941 atcaggtact tcgccttcat gaaaaaggac ccaaacgtgt caaaccaatg actcttccaa
    18001 aagctttacc aaatatggct tctgggaatg tagccatgcg ttttggtgca aacggtgttt
    18061 gtaaatctat caatactgcc tgctcttcat caaatgatgc gattggggat gccttccgct
    18121 ccattaagtt tggtttccaa gatgtgatgt tggtgggagg aacagaagct tctatcacac
    18181 cttttgccat cgctggtttc caagccttaa cagctctctc tactacagag gatccaactc
    18241 gtgcttcgat cccatttgat aaggatcgca atgggtttgt tatgggtgaa ggttcaggga
    18301 tgttggtttt agaaagtctt gaacacgctg aaaaacgtgg agctactatc ctggctgaag
    18361 tggttggtta cggaaatact tgtgatgcct accacatgac ttctccacat ccagaaggtc
    18421 agggagctat caaggccatc aaactagcct tggaagaagc tgagatttct ccagagcaag
    18481 tagcctatgt caatgctcac ggaacgtcaa ctcctgccaa tgaaaaagga gaaagtggag
    18541 ctatcgtagc tgttcttggt aaggaagtac ctgtatcatc aaccaagtct tttacaggac
    18601 atttgctggg ggctgcgggt gcagtagaag ctatcgtcac catcgaagct atgcgccata
    18661 actttgtacc aatgacagct gggacaagtg aagtatcaga ttatatcgaa gctaatgtcg
    18721 tttatggaca aggcttggag aaagaaattc tatacgctat ttcaaatact tttggttttg
    18781 gaggccacaa tgcagttctt gctttcaaac gttgggagaa tagataagta tgaatttaaa
    18841 cgatattaaa gacttgatga ctcaatttga ccagtcaagt ttgagagaat tttcttataa
    18901 aaatgggacg gatgagttgc agtttagcaa gaatgaagca agacctgtgc ctgaagttgc
    18961 aactcaagtc gctccagcac ccgttctagc aacaccgagt ccagtagctc ctacatctgc
    19021 tccagcagag actgtagcag aagaagttcc agctccagct gaagcaagtg tggctactga
    19081 gggaaatctt gtagagagtc cacttgttgg agtggtttac ttggctgctg gaccagataa
    19141 acctgccttt gttacagttg gtgatagtgt caaaaaaggt caaacattgg taattatcga
    19201 agccatgaaa gtcatgaatg aaatcccagc tcctaaggat ggtgtggtaa cggaaattct
    19261 cgtctctaac gaagaaatgg ttgagtttgg taaaggattg gtacgtatca aatgatcgat
    19321 attcaaggaa tcaaagaagc tcttccccac cgttatccta tgcttctagt ggaccgtgtc
    19381 ttggaagtga gcgaggatac cattgttgct atcaaaaatg tgaccattaa cgaacctttc
    19441 tttaacggcc actttcctca atacccagtt atgccaggtg ttctgattat ggaagccttg
    19501 gcgcaaactg ctggtgtgtt ggagttatca aaacctgaaa ataaaggaaa actggtcttt
    19561 tacgctggta tggacaaggt taagttcaag aagcaagttg taccaggcga ccaattggtt
    19621 atgacagcga cttttgtaaa acgtcgtggc accatagctg tggttgaagc aaaggctgaa
    19681 gtggatggca agcttgcagc cagtggtacc cttacttttg caattgggaa ctaaggaggt
    19741 tctccatgtt tcgaaaaatt ttaattgcca atcgtggtga aattgcggtt cgtattatcc
    19801 gtgcggcacg tgaattgggg attgcgacgg tagcggttta ttcaactgct gataaggaag
    19861 ctcttcatac gctgttggca gatgaagcag tttgtattgg tcctggcaag gcaacagagt
    19921 cttatctcaa tattaatgca gttctatcag ctgcagtctt gactgaggca gaagctattc
    19981 accctggttt tggatttctc agtgaaaatt ccaaatttgc gaccatgtgt gaagaagtag
    20041 gtatcaagtt tatcggtcca tctggtcatg ttatggatat gatgggggat aagatcaatg
    20101 cgcgtgctca gatgattaaa gcaggtgtgc ctgttatacc aggttcagat ggagaagtgc
    20161 ataactctga agaagctttg attgttgctg aaaaaattgg ctatcctgtt atgctcaagg
    20221 cttcagcagg tggaggtggt aaagggattc gtaaggttga aaaaccagat gacctcgttt
    20281 ctgcctttga aactgcctct agtgaggcca aggccaatta tggcaatggt gccatgtaca
    20341 tagaacgggt tatctatcca gctcggcaca ttgaggttca aatcctaggt gatgagcatg
    20401 gacatgtgat tcacttgggt gaacgggatt gttctcttca aaggaataac caaaaggttt
    20461 tggaagaaag tccctcgatt gcaatcggaa aaacgctgcg tcatgaaata ggtgctgctg
    20521 ctgttcgagc ggcagagttt gttggctatg agaatgcagg aaccattgaa tttcttcttg
    20581 atgaagcaag tagcaatttc tatttcatgg agatgaatac tcgtgttcag gtagaacatc
    20641 cagtaacaga gtttgtttca ggtgttgata tcgttaagga acagatttgc attgcggcag
    20701 gtcagccttt gtctgttaag caagaagata ttgtcctacg cggtcatgcc atcgagtgtc
    20761 gtatcaatgc agaaaaccca gcctttaact ttgctccaag tccaggtaag attactaacc
    20821 tctatctgcc aagtggtgga gttggcttgc gcgtggattc agcagtttat ccaggttata
    20881 ccattccgcc ttattatgat agtatgattg ccaaaatcat agtacacggc gaaaatcgtt
    20941 ttgacgcctt gatgaaaatg caacgtgccc tctatgaatt agagattgaa ggagtgcaga
    21001 ccaatgcaga tttccagctt gacctcattt cagatcgcaa tgtcattgct ggggattatg
    21061 atacttcctt cttgatggaa accttcttac ctaaatatca agaaaaagaa taaaatgact
    21121 ttaagagttt aaaccgaaaa ggggaatcaa tggctctatt tagtaaaaaa gataagtata
    21181 ttcgaatcaa tcccaatcgt tcggttaggg aaaaacctca agctaagcca gaggttccag
    21241 atgaattatt ttcccagtgt ccaggctgta agcataccat ctatcagaag gatctgggaa
    21301 gtgaacgtat ctgtccgcac tgtagctata cctttcgtat ttctgcccaa gaacgcttgg
    21361 ctttgacgat tgatatggga accttcaaag aattgtttac agggattgaa agcaaggatc
    21421 ccttgcattt ccctggttac caaaagaaac tggcatctat gcgtgaaaaa acaggtctgc
    21481 atgaagccgt tgtgacagga actgctctta ttaaaggtca gactgtggct cttgggatta
    21541 tggattctaa ctttatcatg gcttctatgg gtacggttgt aggtgaaaaa atcactcgtt
    21601 tgtttgagta tgcgactgtc gaaaaattgc cagttgtcct attcacagcc tctggtggag
    21661 cccgtatgca ggaaggaatc atgagtctca tgcagatggc taagatctct gcggcggtta
    21721 aacgtcattc aaatgctggt ctcttttacc tgaccatttt gacagatcca acgactggtg
    21781 gtgtgacagc ttctttcgct atggaaggcg atatcattct ggctgaacca cagagcttgg
    21841 ttggttttgc tgggcgtcgt gtgattgaaa atacggttcg tgaaagcttg cctgaggatt
    21901 tccaaaaggc agaattccta ttagaacatg gctttgtgga tgctattgtc aaaagaagag
    21961 acttaccaga tacgattgct agcctagtca gattgcatgg agggagtcct agatgaatat
    22021 tgcaaaaata gtcagagaag cgcgtgagca gagtcgcttg acaaccttgg actttgcgac
    22081 aggcattttt gatgaattta tccaattaca tggtgaccgt tcttttcgtg atgatggtgc
    22141 agttgttggt ggtattggtt ggcttggaga ccaagctgta acagtggttg gtatccaaaa
    22201 aggcaagagt ttgcaagaca acctcaaacg gaattttggc caaccacatc cagaaggcta
    22261 ccgaaaggca ctgcggttga tgaaacaggc tgagaaattt ggccgtccag ttgtgacctt
    22321 tattaataca gcaggtgctt atcctggtgt cggagcagaa gaacgtggtc aaggggaagc
    22381 tatcgctcgc aatctcatgg aaatgagtga cctgaaagtt cctattatcg ccattattat
    22441 cggtgaaggt ggttcaggcg gggctctggc tctagctgtc gcggaccgtg tctggatgct
    22501 ggaaaattct atctatgcca ttctcagtcc agaaggcttt gcttccattt tatggaagga
    22561 cggtactcgc gccatggaag cagcagaact gatgaaaatc acttcgcatg aactgttaga
    22621 aatggacgtg gtggataagg tgatttctga agtaggactt tctagtaaag aactgattaa
    22681 gagtgtcaaa aaagaactcc aaacggagct ggctagactt tcacaaaaat cgctagaaga
    22741 gttgctggaa gaacgctatc aacgatttag aaaatactaa gaatgactaa atgagactag
    22801 aaaggtctca ttttttatgg aaaaatgcaa ttcaggttga aaaattgata gttgaggaga
    22861 tgggctataa aatagacaaa aaagaaatat actataaatg tgagcctaca acaatctatt
    22921 ttaagaaggt acttgcaatg acaggtacag aaacatttac agttatttca actgaggact
    22981 tggagcaaac ttcaggtggt cttgctgttt gggaagatgg atatagtaga tggttatatt
    23041 atagagaatt tgctccctat atgaggcaag ggcacttaat tcttatatag atgcttggaa
    23101 gtacggcttc cgaacagggt aatctttcaa aaaagtacga tgagaaacac aaagaaacta
    23161 agacaatttg gaatattttt gcttattatt ttactatcta cctatttacc acaaacaatt
    23221 gaattgtatg tgacgatcat tttagggtta ggagctgatg tctattctct tattttaaca
    23281 atggtattag tgggaagttt ccttctatta atttggaggt taaaaaagaa aaagagctgg
    23341 aactggtcat ttgtcttctc cttatttgca acttatgtgg tttatcagat tctcggtaat
    23401 ttttgggcac gctatgctca tttgattaat cataggaata ttcatgatga gtattttacc
    23461 gtggttcttt caaatggaca accaaccttt ttatcgacta tcttatcttt tgtcctgcct
    23521 gtaatcatcg gtcctgtttt tgaggagact cttgatagag ggtattttat gaataccttc
    23581 tttccctagt ccaagtatta tttagatgtc atcttatcag gccttatctt tgggcttagt
    23641 catttgatac tatctcacag agatccaatt agtttattat attatagtct gattggtttc
    23701 ttttttgccc ttgtttatcg ttttaccgac aatctgagat taacgattct ctgccatagt
    23761 tttttttaac tttctcaatc atgcaaaacc tatctggatt tttgtttaca attatatcta
    23821 ttatcatttt tttagatagt gggaggcaaa gaaaaagtgt ttgatatcta tcaaacactt
    23881 tttcttttta ttgttcttct gttacaaact ggctgagcag tccattgata aaacgggcag
    23941 atttttgatc ggagaagtcc tttgcaagct cgatagcttc attaacagca accagctgag
    24001 gagtgtcaaa tgaagtgatt tcaaagactc ccaagcgaag gaggtttctc tccacgagcg
    24061 ttaagcgttc aatggtccaa cctgctttta gatgctgagt gatttgctta tctagttctt
    24121 cctttttagc ttgaacacca gaaacgaggt ctatcaaaaa ggctggaagt tgtacatccg
    24181 tatcttcacg atcatgagta taggcgaaac gacaagcagt ttcgacatcc gtaccgaact
    24241 caaggctcat gagagcttga aaagcgcatt tacggagttg gcgtctagat tctaatagtg
    24301 gactagtcat tgaggaagtc ctcgtcaaat agatctttca attctggttt tggtgtttta
    24361 tctgggacga tacctgcaac gtgaatattg atagcagcga gttctacatc agccatatta
    24421 cggacggcat ctttgacagc tttctggata gcaaccgcta ccttaggaac ttttactccg
    24481 tactcaaggt agagatagat atctgctgtg agttcttcgt ccacgttttt aagataaacg
    24541 ccacggccga gtgaaagttt tgaaagggta tcagacactg atctgtttga aaaagagtga
    24601 acaccctcta cctttgcagt agcgatagca atgatttttt caagtacacg tggggcgata
    24661 acgatttcgc caagttgttc ttcaattccc atagaatgac ctctttctag agattaggca
    24721 cgagaaacgt aagttccttc tgcagtgttg ataacgagtt tttgtcctgc ttcgatgaag
    24781 tctggaacgt ttacgacaag tccagtttcc atcgttgctg gtttaccaga acctgtaaca
    24841 gtagcacctt tgatagatgg ttgagtttca gcaactgtca actcaacagt agtaggaacg
    24901 gtgacaccga tcacttcagt tccgtagaat tggattttca catcagagtt ttcaaggatg
    24961 taaagcaatt cgttttcaac attgactaca gggatttcgt actggtcgta agtttctgta
    25021 ttcatgaagt atgctgtgtc atccattttg tacaagtatt gagctgggac agtctcgata
    25081 atagcttgtt caaatttttc ctctggacgg tagcttgtgt caaatgtaga accagtacgg
    25141 acatcacgca atttcatacg catgatcgtg tttcctttac ctggtttgtg gtgactagct
    25201 tccaaaacgc gaatcaattt gccgtcagct gtttcaaagg tcataccagc ttttaattta
    25261 cttgcttcaa tcatgttttt acctctttaa taaatattat tactcttcat tttaccataa
    25321 aatactctgg aaataaagcc aaaatagtta ttgggagttg gtagagaaga aaaaaccaac
    25381 cttagggctg gttttgttct gtctagtttt ctttcaactt cgccaattcc tgtgcaagta
    25441 gtttaagggc aacttgtggg ttggcttggc ctttggttgc cttcataagg aatcctgtaa
    25501 aggctttgtc ggcgttacgt ttgcctgact tgaagtcggc aacagcagct tcgttatcgg
    25561 caaagacttg gtggatgatt gggatcaaga tagctggatc tgaaatttga accatacctg
    25621 ctttttccac gtattcacgc gcgccaccgc catttttagc tagatggaca aagactttct
    25681 tggcaatctt agatgaaata gtaccgtctt cgatgatggt aatcatttca accaagtttt
    25741 ctggtgtcaa ttcgatttgt tccagtgttt taccttcagc attcaagaac tgagcgactt
    25801 ccccttggag ccagttagag acttgtttgg catcaccacc tagggcaaca gctttttcaa
    25861 agaagtcaga agtgacttta ttagcagtca actgactagc atcgtagtct gataaaccaa
    25921 ggtcagatac ataacgcgca cgacgttctt ttggaaactc tggcaactca gtccgcattt
    25981 cctcaatcca ctcgtcagaa atttcaaaga ggggtaggtc tggttctggg aagtagcggt
    26041 agtctgcagc cccttccttg acacgcatga gaatggttgc tttattcgct tcatcgtaac
    26101 ggcgtgtttc ttggcggatt tgaccacctg agcgaagaat ttcagcctgg cgttggactt
    26161 cgtattcaag acctttacga acgtttgaga aggagttgag gttcttcaat tcagtcttgg
    26221 taccgaattt ttcttgacca taagggcgaa gggagatgtt ggcatccaca cgcatagaac
    26281 cttcttccat cttaacgtca gaaatgccag cgtactggat aacttccttg agggctgtca
    26341 gataagcata ggcctcctct ggcgaacgca tatctgcctc agatacaatc tcaatcaagg
    26401 gaaccccttg gcggttgagg tcaacataag agtagccatc tgtaccatgg gtgtttttac
    26461 cagcgtcttc ctctaggtgg gcacgttcga taccgatttt cttggtcgta ccgtcttcta
    26521 gtttgacttc aatccagcca ttatatccga ttggttcatc aaattgagaa atttggtagg
    26581 ctttggggtt atcaggatag aagtagttct tgcggtcaaa gtgcatcttt ttgtggatgt
    26641 ccatgttgag ggcaagagca gccttgatac cggcatcaac aaccccttta ttgagaactg
    26701 gtagaactcc tgggaaagac cagtcaatca cgttagtgtt ggcattttgg tcatttccaa
    26761 agtgggcaga agtaggtgag aagatttttg aattggtgtt gagctctacg tggacttcaa
    26821 gtccgatgac tgtttcaaag ttcattagtt gtcacctcca aaaatcacgg gttgttgttt
    26881 gtggtagtct gttgttgctt caaaagcagc agcagcttgg taaatggttt cctcagagta
    26941 cttgggacca atcaattgga gtccgacagg tagaccttga gagaatccag caggaatcga
    27001 aattccaggc agtcctgcca agtttacagg tatggtcaat aggtcggcta agtacatggc
    27061 aactgggtca tggttgagag aatccaagtc ataggcaaca cttggagcag ttggacccaa
    27121 aatcaaatcg taatccgcga agactttttc gaaatcttga atgataagtg tacggacctg
    27181 tccagccttc ttatagtagg catcgtagta acctgatgaa agactgaaag tacccagcat
    27241 gatacggcgc ttcacttctt caccaaaacc ttggcttcgg ctgtttacat agatttcatc
    27301 aaggttggtt gcatcttctg cgcgatagcc gtaacggata ccgtcaaagc gttgcaagtt
    27361 tgatgaagct tctgatgaag cgatgatgta gtatacggca actccgtatt tagagtgagg
    27421 aaggctgact tcttcgacaa tagcacccaa tttttcaaag tgtttagcgg catttagaat
    27481 ggtttcctta acctctgggt taattccttc accgaggtat tccttaggca aagcgatttt
    27541 catacccttg atgtcttggc cgatttttga agtaaagtcg gcgatgcgga caggagcaga
    27601 agtagagtct ttagcatctt cgctggcaat agcgttgagc aagagggcat tttccttaac
    27661 agtaggagca aaaggtccaa tctggtctaa tgagctacca aaggcaatga gaccgaaacg
    27721 tgaaactgtt ccgtaggttg gtttgagacc aacgattccg ttgaaggcag caggttggcg
    27781 gatggaacca ccagtatcag aaccaagtga caagcgaact tgtcctgagg ctacagctgc
    27841 ggcagaacca cttgatgacc caccaggaac cttgctgtgg tcccaagcgt ttttagttgc
    27901 tccgtagtgt gaagtttcac ctgaaccacc catagcaaat tcgtccatgt tggtctttcc
    27961 aacgacaatc atgcccttgg tttttgcatt ggcaacagct gtcgcatcaa agattggctc
    28021 atagttgtag agcatttttg aggcagcagt tgtgagaata ccgtctgtag agatgttatc
    28081 cttaacagca agtggaattc ctgaaaggac attgtcagca tcaattccag cttcatcaat
    28141 ggctttagct tgaacaagag cttgctcctc agcgatggtg acaaatgaat tgagggcttc
    28201 ctcacgagac ttgatatttt caagtgttgc ttgggtcaat tctgttgcag aaatttcctt
    28261 agagacaagg agattgtgca actcttcaat agttttattg ttaaaagtca ttaggcatct
    28321 cctccatcgt ctaggatagc tggcaccttg atatagtagt tgtctttttc aggtacgttt
    28381 ttaaacaagc gatcacggtc tgttccttct tcggccacat cagggcggag tacagtcttg
    28441 cggtcagcca tagtcgtagt aggtgcgaca ccagttgtgt caacttcgcc cagcaattca
    28501 accatgtcaa caatcttaga caaggtggtc gcaaaggcag cagtttcttt ttcagagaat
    28561 cttaattttg aaagattggc aacgtgtgtt acctcttctt gcgtaatttt catcttgcat
    28621 cctttcgtga aatgatgatt tttagtctgt tctattttac catattttcc tataaataag
    28681 ggagggggaa gtgaaaagaa atagaaattg aaaaaaatgc taaaatccga tataatggag
    28741 tgttgaaagg aatggtaaaa tccaatgtaa aaatcattct cagctattga aacaagaaaa
    28801 atagagaatc aaagaaagag aacttatgaa tattcaagaa gaaattaaga aacgtcgtac
    28861 ctttgccatt atctcccacc cggacgcggg gaaaacaacc atcactgagc agttactcta
    28921 ctttgggggt gagattcgtg aggctggtac ggtaaaaggg aagaaaacag ggacttttgc
    28981 taaatctgac tggatggata tcgagaagca acgtgggatt tctgttactt catctgttat
    29041 gcaatttgac tacgacggca agcgcgtgaa tatcttagac acgccagggc acgaggactt
    29101 ctcagaagat acctatcgta ccttgatggc ggtggatgct gcggtcatgg tcgtggactc
    29161 tgccaagggg atcgaggctc aaaccaagaa attgtttgag gttgtgaaac atcgtggcat
    29221 tccagtcttt acctttatga acaagctgga ccgtgacggt cgtgagcctt tggatctctt
    29281 gcaagaattg gaagaaatct tgggcattgc tagctaccct atgaactggc ctatcgggat
    29341 ggggaaagcc tttgagggct tgtatgacct ctataaccaa cgtttagagc tttacaaagg
    29401 ggatgagcgt tttgccagtc tagaagacgg ggacaaactc tttggtagca atcctttcta
    29461 cgagcaagtc aaggatgaca ttgagctttt aaatgaagcc gggaatgagt tttcagagga
    29521 agctattctg gctggagaat tgacgcctgt ctttttcggt tcagccctga caaactttgg
    29581 tgtgcagacc ttccttgaaa ccttcctcaa gtttgctcca gaaccacatg gtcacaagaa
    29641 aacagacggt gaaattgtgg atccttatga caaggatttc tcaggatttg tctttaaaat
    29701 ccaagccaac atggaccctc gtcaccgtga ccgtattgcc tttgtccgta tcgtatctgg
    29761 cgaatttgag cgcggcatga gtgtcaatct ccctcgtact ggtaaggggg ctaaactgtc
    29821 taatgttact cagtttatgg cggaaagtcg tgagaatgtg atcaatgccg tggcaggtga
    29881 tattatcggg gtttacgata ccggtactta tcaagttggg gataccttga cagttggtaa
    29941 aaacaagttt gaatttgaac cactgccaac ctttactcct gaaattttca tgaaagtttc
    30001 tgctaagaat gttatgaagc aaaaatcctt ccacaagggg attgagcaat tggtgcaaga
    30061 aggagccgtt cagctttata agaattacca aacaggtgag tacatgctag gcgctgtagg
    30121 tcaactccag tttgaagtct ttaaacaccg catggaaggc gagtacaatg cagaagtagt
    30181 tatgaaccca atgggtaaaa agaccgttcg ttggatcaag cctgaggact tggatgaacg
    30241 gatgtcgtca agtcgcaata tcttagccaa agaccgtttt gaccaaccag tctttctctt
    30301 tgaaaatgac tttgccctcc gctggtttgc ggacaagtat ccagacgtag agttagagga
    30361 gaagatgtga ctcagtacca acaattggaa ctaaagttcc aaattgttgg acgctagtcg
    30421 ctatttggcg aactagctaa ctgcctcact aactacgttt ggcaaataga atcgatttgc
    30481 caaactccgt gtcgtaatat aataatcggt aaccgctatg gcggcttacc taaacgcttc
    30541 actaggaaaa atccacgaat ggtattgatt tgtggatttt tccgtcgtag cagaaagtag
    30601 gtagcctagc taactgcctt actaactacg tttggcaaat gaaatcgatt tgtaaaactc
    30661 cgtgtcgtaa tgtaaaaatt gtaaaccgta atgggacttc atctaaaatc tccactggta
    30721 tggttttacg aacgaatagg cgaaaataat ggttacgtag aaacatatga tgggaataat
    30781 atgatgggaa taaaaagaaa taagataaag agtgaaagaa gagaaaaaag cgattgtctt
    30841 aggtgcagat aatgcttata tggataaagt tgaaacaaca ataaaatctc tttgtgttca
    30901 tcattataat cttaagtttt atgtttttaa tgatgacctt ccgcgagaat ggttccaatt
    30961 gatggaaaaa agactagaga ctttgaatag tgagattgtg aatgttcaga ttgacagtag
    31021 tattctgaaa ggttatcgtc tcccctttga gggactttca tatgcggctt tttttaggta
    31081 ttttattcca aagtatgtaa gcgagtctcg tgtactgtat ttggattcag atattgttgt
    31141 aagaaaatcg atagatgagc tgtgggattt ggacttgacg gctataccct tagctgcagt
    31201 tagagatgat ttttatacac ataattttaa ttctggtgtt ctgttaatca acaatggcat
    31261 gtggagagca gaaaatatca cgcaagacct gatttaagac acaaataaaa aatcttccaa
    31321 ttcccttgca aaaaacaaga aagtgtgata acatagtacg gtatgtggtg ctagcacatc
    31381 cgctatatta gatctaatag gaggaaaaca caatggctaa agtatgttac tttacaggtc
    31441 gtaagactgt atcaggaaac aaccgttcac acgcgatgaa ccaaacaaaa cgtgccgtaa
    31501 aaccaaacct tcaaaaagtt actgttctta tcgatggtaa acctaaaaaa gtttgggctt
    31561 cagctcgtgc tttgaaatca ggtaaagttg aacgcgttta ataataaaag caaaggagac
    31621 cttagggtct tttttctttt attgtgggta taacatcgtt tgaaaaatag agtaaatatc
    31681 cgctgataca ttattctgct tttacacttg ggctgaaata tgataaaata gagtatcaac
    31741 tagttgaggt aaaaaggatg actgtaaaaa ttaatacaaa agatggtcaa atcgaactaa
    31801 cagatgaagt gattgcaacc gtcgtaggtg gagcagcaac tgagattttt ggtgtggtcg
    31861 gtatggctag taaaaatgcc ctcaaagata atttccaagc cctgctaggt aaagaaaatt
    31921 attctaaagg tgtcgtcgta aaggcagccg aagatggcag tattgcagtt gatgtatata
    31981 ctgtgttaag ctacggaaca aagattagtg aagtgtcaaa aaacattcaa gagcgtgttg
    32041 cctttagctt ggaaaaccag cttggaatta ctgctcagac tgtaaatgtc tacattcaaa
    32101 atatcaaagt tgtaggagaa taaccgtgtc aaaaattact actagcttat ttcaagaaat
    32161 ggtgcaggct gcatcaactc gcttgaataa gcaagctgaa tatgtcaatt cattaaacgt
    32221 ctttccagtt ccagatggag atactgggac aaatatggga atgaccattg aaaatggtgc
    32281 taaagaagtt gcagacaagc cagcttctac agttggagaa gtagcgagca ttcttgccaa
    32341 agggcttttg atgggtgcgc gtgggaactc aggagtgatt acgtctcagc ttttccgtgg
    32401 attttcccaa gctatcaagg ataaagacga gttaacaggt caagacttgg ctctggcctt
    32461 ccaatcaggt gtggaagttg cctataaggc agtgatgaaa cctgttgaag gaacgatttt
    32521 gacagtttct cgtggagctg ctatcggtgc taagaaaaaa gctgagcaaa cagatgacac
    32581 tgttgaagtc atgagcgcag ccttggaagg tgctaaaaca gctctagcta aaacaccaga
    32641 catgcttcca gtattgaaag aagttggcgt tgtggactca ggtggtcaag gattggtctt
    32701 catctacgaa ggtttccttt cagcccttac tggcgaatat attgcatctg aggactttgt
    32761 agcgactcct gccaacatga gtgagatgat caatgtagag catcataagt ctgtagctgg
    32821 tcacgtagcg actgaggaca tcacgtttgg ttactgtact gaaatcatgg tagctcttaa
    32881 gcaaggtcca acctatgcta aagattttga ctacgatgaa ttccgtaact acttggatga
    32941 gcttggagat tctctcctcg ttgttaacga tgatgaaatt gtcaaagtcc atgttcatac
    33001 agaagatcca ggacttgtta tgcaagaagg tctcaaatat ggtagcttgg tcaaggtaaa
    33061 agttgacaat atgcgtaacc aacacgaagc acaggttgag aaagaagcta ctcaagttat
    33121 caagtcggct gaagaaaaag agtatgcttt gattgctgtg gtggctggta aaggtctagc
    33181 agatatcttc tgttctcaag gcgtggatta tgttatcgaa ggcggtcaaa ccatgaaccc
    33241 ttcaacagaa gactttatca aggctgttga acaggttaat gcccgtaaca tcatcttctt
    33301 gccaaacaac aagaacatct tcatggcagc tcaatctgcg gcagaagttt tggagcaacc
    33361 agcggtagtg gtagaggctc gcactcttcc tcaaggtatg acaagtcttc ttgcctttga
    33421 tccaagcaag tccattgaag aaaaccaaga gcgtatgaca gctgctctta gcgatgtcgt
    33481 tagcggaagc gtcacaacag ccgtgcgtga tacaacgatc gatggcttag aaatccatga
    33541 aaacgataat ttaggtatgg tggatggaaa aattcttgtg tcaaaccctg atatgcacca
    33601 aacattgact gaaaccttga aacatatgtt ggatgaagac agtgaaatcg taaccttcta
    33661 tgtcggtgaa gacggaagcg aagaacttgc caatgaaatc gctcaagaaa tcgtagaaga
    33721 attcgaagac gttgaagtcg agattcacca aggtcaacaa cctgtttacc catacctatt
    33781 tagtgtggaa taagattaat gaaggactga gaaatcagtt cttttttctt tttagtaaat
    33841 gaaatcggta tctttttaat aaaaacaaaa ataacattca taaataaacg ttaaaataga
    33901 aaattcagaa aatttcttct tttatcttga aaaattttga aaaaatggta tgatagtaac
    33961 aagttatttt taagaggaaa gaaaggggaa taatggagaa aatcagttta gaatctccta
    34021 agacggggtc ggacctagtt ttggaaacac ttcgtgattt aggagttgat accatctttg
    34081 gttatcctgg tggtgcggtt ttgccttttt atgatgcgat atataatttt aaaggcattc
    34141 gccacattct agggcgccat gagcaaggtt gtttgcatga agctgaaggc tatgccaaat
    34201 caactggaaa gttgggtgtt gccgtcgtca ctagtggacc aggagcaaca aatgccatta
    34261 cagggattgc ggatgctatg agcgatagcg ttcccctttt ggtctttaca ggtcaggtgg
    34321 cgcgagcagg gattgggaag gatgcctttc aggaggcaga catcgtagga attaccatgc
    34381 caatcactaa gtacaattac caagttcgtg agacagctga tattccgcgt atcattacgg
    34441 aagctgtcca tatcgcaact acaggccgtc cagggccagt tgtaattgac ctaccaaaag
    34501 acatatctgc tttagaaaca gacttcattt attcaccaga agtgaattta ccaagttatc
    34561 agccgactct tgagccgaat gatatgcaaa tcaagaaaat cttgaagcaa ttgtccaagg
    34621 ctaaaaagcc agtcttgtta gctggtggtg gaattagtta tgctgaggct gctacggaac
    34681 taaatgaatt tgcagaacgc tatcaaattc cagtggtaac cagtcttttg ggacaaggaa
    34741 cgattgcaac gagtcaccca ctctttcttg gaatgggagg catgcacggg tcattcgcag
    34801 caaatattgc catgacggaa gcggacttta tgattagtat tggttctcgt ttcgatgacc
    34861 gtttgacggg gaatcctaag actttcgcta agaatgctaa ggttgcccac attgatattg
    34921 acccagctga gattggcaag attatcagtg cagacattcc tgtagttgga gatgctaaga
    34981 aggccttgca aatgttgcta gcagaaccaa cagttcacaa caatactgaa aagtggattg
    35041 agaaagtcac taaagacaag aatcgtgttc gttcgtatga caagaaagag cgtgtggttc
    35101 aaccgcaagc agttattgaa cgaattggtg aattgacgaa tggagatgcc attgtggtaa
    35161 cagacgttgg tcaacaccaa atgtggacag ctcagtatta tccctaccaa aatgaacgtc
    35221 agttagtgac ttcaggtggt ttgggaacaa tgggctttgg aattccagca gcaatcggtg
    35281 ctaaaattgc taacccagat aaggaagtag tcttgtttgt tggggatggt ggtttccaaa
    35341 tgaccaacca ggagttggct attttgaata tttacaaggt gccaatcaag gtggttatgc
    35401 tgaacaatca ttcactcgga atggttcgcc agtggcagga atccttctat gaaggcagaa
    35461 catcagagtc ggtctttgat acccttcctg atttccaatt gatggcgcag gcttatggta
    35521 ttaaaaacta taagtttgac aatcctgaga ccttggctca agaccttgaa gtcatcactg
    35581 aggatgttcc tatgctaatt gaggtagata tttctcgtaa ggaacaggtg ttaccaatgg
    35641 taccggctgg taagagtaat catgagatgt tgggggtgca gttccatgcg tagaatgtta
    35701 acagcaaaac tacaaaatcg ttcaggagtc ctcaatcgct ttacaggtgt cctatctcgt
    35761 cgtcaggtta atattgaaag catctctgtt ggagcaacag aagatccgaa tgtatcgcgt
    35821 atcactatta ttattgatgt tgcttctcat gatgaagtgg agcaaatcat caaacagctc
    35881 aatcgtcaga ttgatgtgat tcgcattcga gatattacag acaagcctca tttggagcgc
    35941 gaggtgattt tggttaagat gtcagcgcca gctgagaaga gagctgagat tttagcgatt
    36001 attcaacctt tccgtgcaac agtggtagac gtagcgccaa gctcgattac cattcagatg
    36061 acgggaaatg cagaaaagag cgaagcccta ttgcgagtca ttcgcccata cggtattcgc
    36121 aatattgctc gaacgggtgc aactggattt acccgcgatt aaaaatccaa cttaaatttg
    36181 ttaaaccagc ttaaaaggca ataaataata gaaaagagag aaaagctatg acagttcaaa
    36241 tggaatatga aaaagatgtt aaagtagcag cacttgacgg taaaaaaatc gccgttatcg
    36301 gttatggttc acaagggcat gcgcatgctc aaaacttgcg tgattcaggt cgtgacgtta
    36361 ttatcggtgt acgtccaggt aaatcttttg ataaagcaaa agaagatgga tttgatactt
    36421 acacagtaac agaagctact aagttggctg atgttatcat gatcttggcg ccagacgaaa
    36481 ttcaacaaga attgtacgaa gcagaaatcg ctccaaactt ggaagctgga aacgcagttg
    36541 gatttgccca tggtttcaac atccactttg aatttatcaa agttcctgcg gatgtagatg
    36601 tcttcatgtg tgctcctaaa ggaccaggac acttggtacg tcgtacttac gaagaaggat
    36661 ttggtgttcc agctctttat gcagtatacc aagatgcaac aggaaatgct aaaaacattg
    36721 ctatggactg gtgtaaaggt gttggagcgg ctcgtgtagg tcttcttgaa acaacttaca
    36781 aagaagaaac tgaagaagat ttgtttggtg aacaagctgt actttgtggt ggtttgactg
    36841 cccttatcga agcaggtttc gaagtcttga cagaagcagg ttacgctcca gaattggctt
    36901 actttgaagt tcttcacgaa atgaaattga tcgttgactt gatctacgaa ggtggattca
    36961 agaaaatgcg tcaatctatt tcaaacactg ctgaatacgg tgactatgta tcaggtccac
    37021 gtgtaatcac tgaacaagtt aaagaaaata tgaaggctgt cttggcagac atccaaaatg
    37081 gtaaatttgc aaatgacttt gtaaatgact ataaagctgg acgtccaaaa ttgactgctt
    37141 accgtgaaca agcagctaac cttgaaattg aaaaagttgg tgcagaattg cgtaaagcaa
    37201 tgccattcgt tggtaaaaac gacgatgatg cattcaaaat ctataactaa ttagaaatat
    37261 atagcgctgg agatgatttt atgaaaaaga ttatgagaaa aattgcatcg ttattattgg
    37321 ttctagttgt ataatgtaat tacaccgtcg gtaatagtgc tagcagacca aaataaagca
    37381 gattggtcgt atgatgaaaa tactgtaatt aacatttatg atgatgctaa ttttgaagat
    37441 ggtaggttgc atatgacctt tgaacaattc ttcaaattgg cacaaatagc tagagaagaa
    37501 ggtcttgaaa ttcattcttc gtttgagaga gctggtgcga ctaaatctgc tcgttatata
    37561 gcgaaatgga ttttgagaaa taaaaaacat taacaaatat agttggtaaa tcattaggac
    37621 ctaaatcagc tgttagattc ggagaagctt tatcctatat tgaaggtcct cttcgcagaa
    37681 taaatgagac gatagatggc ggtttatatc aaatagagca aattattgca tctggattga
    37741 aagaatcggg tttaaatgac tggactgcga aaactttagc ttcagctatt cgtgggatat
    37801 tagatgtact tatttagggg ttgaaatcat atgaatatta ccaatttgtt ttctatcaag
    37861 acaggatgtg atgaaactga taggcaactg caaaaactat tttttcagtt ggatttacaa
    37921 ttgggagaat tgacagatca actaagaaaa ttagattcta attttgttcc tcgtagtcaa
    37981 tttgtagaca cgttggattt gaatgatgta gaatataaag aaattttaaa ctattttatc
    38041 ttccatcgta atgatagtga agaaagtttg gtagaatggt tatatgattg gatttccaca
    38101 aatcgttatg agcttcctaa agagttttcg attcgtatgg ctcataaata ccatgaaagt
    38161 gttactgaag ttttcggaga tgaataacta aaaaacagtc attagtgact gttttttata
    38221 gaaaaagagg ttttatatgt taagttcaaa agatataatc aaggctcaca agatcttgaa
    38281 cggtgtggtt gtgaatactc cactggatta cgatcattat ttatcggaga agtatggtgc
    38341 taagatttat ttgaaaaaag aaaatgccca gcgtgttcgc tcctttaaaa ttcgtggtgc
    38401 ctattatgcc atttcccagc tcagcaagga agaacgtgaa cgtggggtag tctgcgcttc
    38461 tgcgggaaat catgcgcagg gagtagccta tacttgtaat gaaatgaaaa ttcctgctac
    38521 tatctttatg cctattacta cgccacaaca aaagattggt caggttcgct tttttggtgg
    38581 ggattttgta actattaaac tagttggaga tacctttgat gcctcagcca aagcagctca
    38641 agaatttaca gtctctgaaa atcgtacctt tattgatcct tttgatgatg ctcatgttca
    38701 agcaggtcaa ggaacagttg cttatgagat tttagaagaa gctcgaaaag aatcgattga
    38761 ttttgatgct gtcttggttc ctgttggtgg tggcggtctc attgccgggg tttctaccta
    38821 tatcaaggaa acaagtccag agattgaggt tatcggagta gaggcgaatg gagcgcgttc
    38881 catgaaagct gcctttgagg ctggaggtcc agtcaaactc aaggaaattg ataaatttgc
    38941 ggatgggatt gctgtgcaaa aggtaggtca gttgacctat gaagcaactc gtcaacatat
    39001 taaaactttg gtaggtgtcg atgagggatt gatttctgaa accttgattg acctttactc
    39061 taagcaaggg atagtcgcag aacctgctgg agcggctagt atcgcctctt tagaggtttt
    39121 agctgaatat attaagggga aaaccatttg ttgtatcatt tctggaggaa ataatgatat
    39181 caaccgtatg ccagaaatgg aagagcgtgc cttgatttat gatggtatca aacattactt
    39241 tgtggtcaat ttcccacaac gtccaggagc tttgcgtgag tttgtaaatg atatcctggg
    39301 gccaaatgat gatatcacac gttttgagta tatcaaacga gctagcaagg gaacaggccc
    39361 agtattaatt gggatcgctt tagcagataa gcatgattat gcaggtttga ttcgtagaat
    39421 ggaaggtttt gatccagctt atattaactt aaatggtaat gaaacgcttt ataatatgct
    39481 tgtctgagga ctaataaaaa aatatcatat tatttgtaca actgatgtat atgtgctata
    39541 atgaagatga agaaagggga cgatttctat ggttttagga aacttatcgt gcaattctta
    39601 cttctgttca ttatagcact tatgatgttt ggctcagatt tccatccttc attttgattt
    39661 cctatctatt gacaagcata gtcacactgt ctttaatact cttcgaaaat ctcttcaaac
    39721 cacgttagct ctatctgcaa cctcaaaaca gtgttttgag caacttgcgg ctagcttcct
    39781 agtttgctct ttgattttca ttgagtataa ggtatgattt gatttctttt tgttgacaaa
    39841 tataccatat taaaaagata tataagtaat taactgagct tatctgtctt gtcatctcta
    39901 ttaaggatgg tttagataat cgggtgtctg cttctaggct agcacctcaa tatccaaagg
    39961 agtgatgaat ttgaaggata taaggaatac ctatctctca gatgatttat tgaggaagaa
    40021 agataggagt ttttgagcta gtgaaggctt ggatttctaa aggttagaac tatcatcttc
    40081 agttcttaaa tcgaagaaat aagctatctt acggaaatag agaagcattt tttaagaact
    40141 tgaataattt cgcaccttaa gagggtaata atacagtatt tttattagca aatatttatg
    40201 gtgtagagac tagtaaaacc tatatattat cggattcaaa aaggaagtaa gaaaattctg
    40261 aagctaaaat tctgaactaa ttattttcgt tgaatacatg tttttttatt gacaaaagta
    40321 gtaaaaacgt atacaattaa atattataaa gaagaaaata ggagaaaaac atggctaagt
    40381 caaactttga aaaagtagaa tcagttgttg gctgggttcg tgataagaaa atcacaggct
    40441 accgtatctc taaagaaacg aatgcgcgtg aaatgtctat cattgctctg gcgcagggtc
    40501 gtgcaaaagt aaaaaatatt tcatttgaaa cagccctagg cctaattgat ttctatgaaa
    40561 aaaatcatga aaaatttgaa gattaatctt tggataacgg cggattcttg accttcaagt
    40621 agtagagata gagaatctgc cttttcattt tgaggacagc aaaaagactg cacggttgat
    40681 gcagcctttt ctttttattt gagatagcgt tgaaggaact cttttgttcg gtcttcttta
    40741 ggattggtga agaggtcttc tggtttacct tcttcagcga tcacgccctt atccataaag
    40801 ataacacggt gagagacatc acgggcaaat tccatttcat gggttacgac aatcatggtc
    40861 aagccttcct gagccagatc ttgcatgatt ttgaggacct ctccaaccat ttctggatcg
    40921 agagctgatg ttggttcatc aaagagaatg gcgtcaggat tcattgaaag ggcacgagca
    40981 atggccacac gttgtttttg accacctgag agttgtttgg gtttagcttg ccagtagcgt
    41041 tctcccatgc cgaccttttc caggttttct ttggcaattt cttcagcttc tgtgcgttcg
    41101 cgtttaagga cagttgtctg agcgacgatt gtgttttcaa gaacgttgag attttcaaag
    41161 aggttaaagg attggaaaac catccctaac ttttcacggt attgcgtgag gtcatagcct
    41221 ttttcgagga cgttttgtcc atgataaagg atttgtccat cagttggcgt ttcaagtagg
    41281 ttaatggagc gtaggaaggt tgatttccca cttccagagc ttccgatgat agaaataact
    41341 tctcccttgt ggacagtgag agaaatgtct tttagcactt cgttttgtcc ataggatttt
    41401 ttgaggtgtt taatttcaag gattgcttgt gtcattattt caaatcctcc gtttgcattt
    41461 ggttagcacc tgtagtgtag gtatccatgt ccattctgcg ctcgataaag cgtaggatac
    41521 gtgttacggt gaaggtgagg acaaagtaaa tcacggcgat gattgtaaat gtctggaagt
    41581 attgataggt ttgtgttgcc acggtatttc ctgagaaata aagttcgaca acagagataa
    41641 cgttcaatac agatgtatct ttgatattga tgacaaattc attaccagtt gcaggtagga
    41701 tgttacggac tacctgaggt aggacaatct tacgcatggt ctggttatgg gtcataccaa
    41761 gagcagtcgc agcttcaaat tgtcccttgt caactgctag gataccacca cggacgattt
    41821 cagtcatgta ggcaccggta ttgattgaaa cgatgaagat agcagccagt gtacggtcaa
    41881 ggttgatccc gaaagcttgg gcagttccat agtagataac catcgattga acaatcattg
    41941 gcgtaccacg gaaaatttca atgtagacat tgagaaccca gccgactagt ttttgaaggc
    42001 cataaatggc tttgttttca gagagaggag cagtacggaa gacaccaatg gcaagtccaa
    42061 taatgagacc tatgatggtt ccgacgatag agattaaaag agtgatacca gcaccacgca
    42121 agagttgttg ccagttttca gaaagaattt tagcgacttg gctaaagaaa ctactgctag
    42181 tctcttcagt tgttgtagct tcggcaggtt gttccttgat catacgatcc atcagggcaa
    42241 cttggtcgtc ctttgaaatg gtttcaatgc tggcattgat ttggctaata cgattgtcat
    42301 ttttacgaag cccgatagcg atagctgtat cttcttcccc agttttgaaa ccaggttcta
    42361 cttgaatcat cttgaactta gagttcgcag cttcagcagt cagtgcttct ggacgttcag
    42421 aaacataagc atcaatgaca ccagcctcaa gagcttgtcg catttgagcg aagtctccca
    42481 tggctgtttc ttttttagca cctgggattt gtgcaatcaa gtcgtagagg tagacccctt
    42541 gttgagaagt gatttttgca ccgttaaagt catccaaaga tttagcactt gcgtaggcag
    42601 aatctttttt gacaagcaaa actggttcgc tagtgtagta actgctcgaa aaggcaattt
    42661 cttgtttgcg ttctgcagtt ggactcatac ctgcgataat catgtcaatc ttaccagaag
    42721 taagggcagg gactagacct tcccacttgg ttttaacaac caaaggttct ttacctaagt
    42781 ccttagcgat tttcttggcg atttgaacat cgtatccgtt ggcatactga ttggtcccat
    42841 cgattttgac agctccgttg ctatcatcat cctgggtcca gttaaaggga gcatatgctg
    42901 cttccatccc gatgcgtaaa tattcatcgg cttgagcaac attgacaagt cctagcatca
    42961 gcaagagact tgtgaaaata gataagtata tttttctcat gatttctcct attctgatct
    43021 attaaaaaat aactgtctcc tattttatcg aaaaatgcgt aatttttcaa cataagtaag
    43081 cctttactta cgaaaaaatg ctataatgat aagaaagata aaaagggggc ttagttgatg
    43141 aaaaaaactt ttttcttact ggtgttaggc ttgttttgcc ttcttccact ctctgttttt
    43201 gccattgatt tcaagataaa ctcttatcaa ggggatttgt atattcatgc agataatacg
    43261 gcagagttta gacagaagat agtttaccag tttgaggagg actttaaggg acaaatcgtg
    43321 ggacttggac gtgctggtaa gatgcctagc gggtttgaca ttgaccctca tccaaaggtt
    43381 caggccgcga aaaacggtgc agaactagca gatgtgacta gcgaagtaac agaagaagcg
    43441 gatggttata ctgtgagagt ctataatcca ggtcaggagg gcgacatagt tgaagttgac
    43501 ctcgtctgga acttaaaaaa tttacttttc ctttatgatg atatcgctga attaaattgg
    43561 caacctctga cagatagttc agagtctatt gaaaagtttg aatttcatgt aaggggagac
    43621 aagggggctg aaaaactctt tttccataca gggaaacttt ttagagaggg aacgattgaa
    43681 aagagtaacc ttgattatac tatccgttta gacaatcttc cggctaagcg tggagttgag
    43741 ttgcatgcct attggcctcg gaccgatttt gctagcgcta gggatcaggg attgaaaggg
    43801 aatcgtttag aagagtttaa taagatagaa gactcgattg ttagagaaaa agatcagagt
    43861 aaacaactcg ttacttgggt cctcccttcg atactttcta tctccttgtt attgagtgtc
    43921 tgcttctatt ttatttatag aagaaagacc actccttcag tcaaatatgc caaaaatcat
    43981 cgtctctatg aaccaccaat ggaattagag cctatggttt tatcagaagc agtctactcg
    44041 acctccttgg aggaagtgag tcccttggtc aagggagctg gaaaattcac ctttgatcaa
    44101 cttattcaag ctaccttgct agatgtgata gaccgtggga atgtctctat catttcagaa
    44161 ggagatgcag ttggtttgag gctagtaaaa gaagatggtt tgtcaagctt tgagaaagac
    44221 tgcctaaatc tagctttttc aggtaaaaaa gaagaaactc tttccaattt gtttgcggat
    44281 tacaaggtat ctgatagtct ttatcgtaga gccaaagttt ctgatgaaaa acggattcaa
    44341 gcaagagggc ttcaactcaa atcttctttt gaagaggtat tgaaccagat gcaagaagga
    44401 gtgagaaaac gagtttcctt ctgggggctc ccagattatt atcgtccttt aactggtggg
    44461 gaaaaggcct tgcaagtggg tatgggtgcc ttgactatcc tgcccctatt tatcggattt
    44521 ggtttgttct tgtacagttt agacgttcat ggctatcttt acctcccttt gccaatactt
    44581 ggttttctag ggttagtttt gtctgttttc tattattgga agcttcgact agataatcgt
    44641 gatggtgttc taaatgaagc gggagctgag gtctactatc tctggaccag ttttgaaaat
    44701 atgttgcgtg agattgcacg attggatcag gctgaactgg aaagtattgt ggtctggaat
    44761 cgcctcttgg tctatgcgac cttatttggc tatgcggaca aggttagtca tttgatgaag
    44821 gttcatcaga ttcaagtgga aaatccagat atcaatctct atgtagctta tggctggcac
    44881 agtatgtttt atcattcaac agcacaaatg agccattatg ctagtgtcgc aaatacagca
    44941 agcacctact ctgtatcttc tggaagtgga agttctggtg gtggcttctc tggaggcgga
    45001 ggtggcggca gtatcggtgc cttttaaaga gagctaccat agactgaaaa agtatgatat
    45061 aatggaagat agaaaaaaga caaactataa gaaaagtcaa tagttttatc taaactattt
    45121 cttatttcaa tttgatgatt tggcgatgat tttagagcac ggcaaaaagc tattgaaaaa
    45181 gtccattttt tcaaaggtaa tcctgtgtta atttcagaaa ttatatcact ttttgttcgt
    45241 caaatggcag ctctttttta ggatataaaa cagggttcgg ataagttttt ttgcaaggtg
    45301 gatgatggct acattgtaat gttttcctt
//
LOCUS       DAVLCS010000012        44815 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLCS010000012 DAVLCS010000000
VERSION     DAVLCS010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44815
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.012"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(58..867)
                     /locus_tag="VXC78_000785"
     CDS             complement(58..867)
                     /locus_tag="VXC78_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0582899.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(869..1672)
                     /locus_tag="VXC78_000786"
     CDS             complement(869..1672)
                     /locus_tag="VXC78_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0582900.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYELLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1682..3169)
                     /gene="tacF"
                     /locus_tag="VXC78_000787"
     CDS             complement(1682..3169)
                     /gene="tacF"
                     /locus_tag="VXC78_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV0582901.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIIKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNRIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIILLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3505..4212
                     /locus_tag="VXC78_000788"
     CDS             3505..4212
                     /locus_tag="VXC78_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV0582902.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKNIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4217..5239
                     /locus_tag="VXC78_000789"
     CDS             4217..5239
                     /locus_tag="VXC78_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0582903.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLL
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5256..6125
                     /gene="licA"
                     /locus_tag="VXC78_000790"
     CDS             5256..6125
                     /gene="licA"
                     /locus_tag="VXC78_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV0582904.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIGSAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            6115..6993
                     /locus_tag="VXC78_000791"
     CDS             6115..6993
                     /locus_tag="VXC78_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV0582905.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7005..7694
                     /locus_tag="VXC78_000792"
     CDS             7005..7694
                     /locus_tag="VXC78_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV0582906.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYVSGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7790..8638
                     /gene="dprA"
                     /locus_tag="VXC78_000793"
     CDS             7790..8638
                     /gene="dprA"
                     /locus_tag="VXC78_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV0582907.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9527..10570
                     /locus_tag="VXC78_000794"
     CDS             9527..10570
                     /locus_tag="VXC78_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV0582908.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            10737..12824
                     /gene="topA"
                     /locus_tag="VXC78_000795"
     CDS             10737..12824
                     /gene="topA"
                     /locus_tag="VXC78_000795"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV0582909.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            12930..13289
                     /locus_tag="VXC78_000796"
     CDS             12930..13289
                     /locus_tag="VXC78_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV0582910.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYILMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13382..14014
                     /locus_tag="VXC78_000797"
     CDS             13382..14014
                     /locus_tag="VXC78_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV0582911.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            14058..14714
                     /locus_tag="VXC78_000798"
     CDS             14058..14714
                     /locus_tag="VXC78_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV0582912.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14733..15365
                     /locus_tag="VXC78_000799"
     CDS             14733..15365
                     /locus_tag="VXC78_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV0582913.1"
                     /translation="MNFQLAKYSLLKKFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     CSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            15393..15827
                     /locus_tag="VXC78_000800"
     CDS             15393..15827
                     /locus_tag="VXC78_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEV0582914.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            15839..16876
                     /gene="leuB"
                     /locus_tag="VXC78_000801"
     CDS             15839..16876
                     /gene="leuB"
                     /locus_tag="VXC78_000801"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV0582915.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKHAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            16873..17142
                     /locus_tag="VXC78_000802"
     CDS             16873..17142
                     /locus_tag="VXC78_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV0582916.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRTWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            17146..17505
                     /gene="leuD"
                     /locus_tag="VXC78_000803"
     CDS             17146..17505
                     /gene="leuD"
                     /locus_tag="VXC78_000803"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV0582917.1"
                     /translation="MAGSSREHAAWVLADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17667..18290
                     /locus_tag="VXC78_000804"
                     /pseudo
     CDS             17667..18290
                     /locus_tag="VXC78_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            18456..20369
                     /locus_tag="VXC78_000805"
     CDS             18456..20369
                     /locus_tag="VXC78_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV0582918.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSINSRQNLSVNYDSGVSGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNDQ
                     TGQQDTGDNDADY"
     gene            20356..21672
                     /locus_tag="VXC78_000806"
     CDS             20356..21672
                     /locus_tag="VXC78_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV0582919.1"
                     /translation="MRITDNQYKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            21847..22833
                     /locus_tag="VXC78_000807"
     CDS             21847..22833
                     /locus_tag="VXC78_000807"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV0582920.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            22897..22968
                     /locus_tag="VXC78_000808"
     tRNA            22897..22968
                     /locus_tag="VXC78_000808"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22930..22932,aa:Arg,seq:ccg)
     gene            23151..23849
                     /locus_tag="VXC78_000809"
     CDS             23151..23849
                     /locus_tag="VXC78_000809"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV0582921.1"
                     /translation="MKELQTVLKNHFAIEFTDKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTYLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            23840..27379
                     /gene="smc"
                     /locus_tag="VXC78_000810"
     CDS             23840..27379
                     /gene="smc"
                     /locus_tag="VXC78_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV0582922.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQDEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRQQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            27376..28170
                     /locus_tag="VXC78_000811"
     CDS             27376..28170
                     /locus_tag="VXC78_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0582923.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            28170..28988
                     /locus_tag="VXC78_000812"
     CDS             28170..28988
                     /locus_tag="VXC78_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0582924.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEKTE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGINQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVMPMTNDEEAVAWAIEEYVLKEN"
     gene            28992..30281
                     /gene="ftsY"
                     /locus_tag="VXC78_000813"
     CDS             28992..30281
                     /gene="ftsY"
                     /locus_tag="VXC78_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV0582925.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(30325..31812)
                     /locus_tag="VXC78_000814"
     CDS             complement(30325..31812)
                     /locus_tag="VXC78_000814"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV0582926.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(31961..32701)
                     /locus_tag="VXC78_000815"
     CDS             complement(31961..32701)
                     /locus_tag="VXC78_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0582927.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(32701..34866)
                     /locus_tag="VXC78_000816"
     CDS             complement(32701..34866)
                     /locus_tag="VXC78_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0582928.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            35036..35989
                     /locus_tag="VXC78_000817"
     CDS             35036..35989
                     /locus_tag="VXC78_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0582929.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            36066..38054
                     /gene="uvrB"
                     /locus_tag="VXC78_000818"
     CDS             36066..38054
                     /gene="uvrB"
                     /locus_tag="VXC78_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV0582930.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            38065..38628
                     /locus_tag="VXC78_000819"
     CDS             38065..38628
                     /locus_tag="VXC78_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0582931.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLVLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            38594..39082
                     /locus_tag="VXC78_000820"
     CDS             38594..39082
                     /locus_tag="VXC78_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0582932.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            39156..39623
                     /locus_tag="VXC78_000821"
     CDS             39156..39623
                     /locus_tag="VXC78_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0582933.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(39620..40135)
                     /locus_tag="VXC78_000822"
     CDS             complement(39620..40135)
                     /locus_tag="VXC78_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV0582934.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(40147..40674)
                     /locus_tag="VXC78_000823"
     CDS             complement(40147..40674)
                     /locus_tag="VXC78_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0582935.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(40956..41519)
                     /locus_tag="VXC78_000824"
     CDS             complement(40956..41519)
                     /locus_tag="VXC78_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0582936.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(41503..42054)
                     /gene="coaC"
                     /locus_tag="VXC78_000825"
     CDS             complement(41503..42054)
                     /gene="coaC"
                     /locus_tag="VXC78_000825"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV0582937.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(42066..42755)
                     /gene="coaB"
                     /locus_tag="VXC78_000826"
     CDS             complement(42066..42755)
                     /gene="coaB"
                     /locus_tag="VXC78_000826"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV0582938.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKNLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            42985..44655
                     /locus_tag="VXC78_000827"
     CDS             42985..44655
                     /locus_tag="VXC78_000827"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV0582939.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
BASE COUNT        13877 a         7882 c         9770 g        13286 t
ORIGIN      
        1 actaaaatta tgtttttgaa taacctctat cttagtagtt tgtataatcc ccctcaatca
       61 gtttttgcga taagctttaa tgctatgact ataccactct tgcatttctt ttgatggtgg
      121 tgtcatataa tcgccataca tctgggttaa aaattggtca tattttttgg gaacaggcaa
      181 catacggccc tcaaactcag ttaaaatcag ttctttaaag gtatcaactg ggaagatttc
      241 tttcatccct tccttaccga tcccaactcc tccttcatat tgaggaatgt tggttacagc
      301 atttttgact agttgatcaa ttttcttgta aaagtagcga ggattgacaa atcggagagc
      361 gtaccagcta cataatctaa gaaaatcttt tagtttgcta tcaccgtgaa ctgctcgtga
      421 ttttttgata taagctagtt gacgaagagc cacatactta tagctcttgt cgacaatgct
      481 caagtctgta aatcgatcaa ttgggaagac atcgatgaaa aggctggtat catgacgctt
      541 gtacttaaca tggtcttcta taacagtaga agtgtccaaa atcgatgcga aattatggaa
      601 gtaccaagaa gatgtatcgt aggaaagaac cttgtagcga gggtgatttt cttcttcaat
      661 aatcttcagt aaacgctcat aatcctcacg ataaagggaa atatcaatat catcatccca
      721 aggaatcata cctttgtggc ggatggctcc aagcatggtt ccataactga gaaaataagg
      781 aatatcatgt ttcttacaag tctcatcaat atagtccagc agggctagtt gaatttcttt
      841 aatttctttt ttttctaaat attgcatcct aatcctccaa tttataagcg tgaaattcat
      901 gactgtagaa gcgtttttct tctggtggta gggtcatata atctccataa aattgtgtca
      961 aaatagtatc aaatttttca ggtgcaggaa ggcttaaatt ctcaaagggt aaatcgattg
     1021 ttttatcaaa ggtaccactt gggaagactt ccttttcctt aaattttgaa gggataaaag
     1081 ccatatactg cccattttca cgactatatt tttgaatttc tttctcgatt ttatttgcaa
     1141 aataacgagg agaaactggt cgaaggagca accaaaaggc tgttcgtatc caatctttta
     1201 aaaggctatc cttatagaca atatttttat gtttactgaa agacagcagt ttgaagcttt
     1261 ccagtttata acaagtatca atgaccttag gatcatcaaa gcgatccata gggaaaatat
     1321 cgataaagat accagactca taggtttttg tatttcgagt atcaataatt ttagtcgtac
     1381 tgtcggttat cttgataaag ttgttaaagt agttcttatc agtttctaag gataggagtt
     1441 catacttgct tttttccttt tgaaaaatgt taataaatcg ttggtagtct tctctaggca
     1501 tggataaatc aatatcgtcg tcccaaggga taaagccctc atgtcgaacc gccccaatca
     1561 gagtaccgta gttaataata tagttgatat tgtgcttttt acagagagta tcaatataat
     1621 ccaaaatttc taattcaatt tgtttggcat cttcaacggt tagttgtttc attttaaact
     1681 cctatgattt tttaaattta ttttttaagg ctagaacatg gtttaaaaat tcatagaaaa
     1741 tgctatcttt tgtgaagaca agtagactaa tataagagat agctgatagc aagataatca
     1801 aaccagtatt aatcaaaaat ggcaaattaa tgaccatatc cacaggatac acgaaattaa
     1861 tcaggaaata aattgctaca aaggaaagtg aaaagagaga gtatcgaaca gtatagctaa
     1921 agatatgtcc caagtggatg agttgttttc tatggatgaa aatgatatag aaaacaagta
     1981 gagaagcctc tgataacata gttgtcagta agtagtattc gggagccacg atacggttga
     2041 aaaagaggag actattcaag cccaaattga gtagcccagc aaagactgta taaactgtga
     2101 tacgtttttc atagccattg gtaaagagaa tttgggaacc aagaatggta tctaaggcca
     2161 ggataatcgt acgaaaagcg aagagagagg tcaagatgcc gcctccgata tatttttcac
     2221 taccgtaaag taggatggca tttggtccta aaaccatgag tccaaaactc agtggaatga
     2281 taaagaagtt aaagattcga ctacctctat taaccagaga aacataggct tctttgtctc
     2341 ctttccccag atagtaactg agacgaggca cactcactcc aattgcacct gttacaaccc
     2401 cagctataac ggtcacaatt cgctgagcta tggtatagta actaacgttg acatcaatcc
     2461 ctgttttaac gaggaagagg cgatctaaaa aagtgaagag catattggca ttggcaaaga
     2521 ctaacatggc tgtcagaggg agaaagagtg gtttaaaatc acttaggtga atcttaacaa
     2581 gtttgatgtc tcttttaatc caaaaataac taatcaggta gttaatcagc gtcgataaac
     2641 tcatcacaag tgtatagaca acaatatcgt gttcattttt aacaaataag aaaatagaga
     2701 ccagcatcag gatacggatg aaggcagttt tgtaaaagag aaaactgtaa ttttccagag
     2761 cttcattgac ccattcgatt gaaaaaatct gggcaatgag ttgaatcccc ataacaaggt
     2821 agaccttttt gatgattgga ttatcagtaa agaagagagg ataggctagg atatagacag
     2881 cagtggtcaa aatcgtacaa gcgatgcaca aataaaaaag actagaaaag gttctgttaa
     2941 gatctttttt gttatccttg acattactga tagcccttaa accgtagtta tagacaccat
     3001 aagttgcaaa gggcaagaaa aatgacaaaa tagtgtcgac tgagttgaag taaccatagt
     3061 cagttcggtc caagacacgc gcgacatagg ttccagttag gatgggaaaa ataatattca
     3121 agacacgaat tcccatgtaa gatagagcat ttaattttat acttttcatt caatttacct
     3181 cgtttttcat tatatcataa agttagctaa taagaaatga agggcagtaa gtcaagtaat
     3241 cactttgaag tttcaaatct taagttttaa gttttcttta aggaaagtat attattctga
     3301 aggactctaa aatttcgcag ccatttatta gtaattgcta cagaattcct agtcattact
     3361 agaaatggac tagtttcttt gaataataga actgcataat tctcctattc tagaagggga
     3421 ggaccagtat ttcttttatg ataggactag attgtggtat aatagagaga ataagttttt
     3481 ttagtaagac aaaggagaaa atagatgatt tatgcaggaa ttcttgccgg tggaactggc
     3541 acacgcatgg ggatcagtaa cttgccaaaa caatttttag agctaggtga tcgacctatt
     3601 ttgattcata caattgaaaa atttgtcttg gagccaagta ttgaaaaaat tgtagttggt
     3661 gttcatggag actgggtttc tcatgcagaa gatcttgtag ataaatatct tcctctttat
     3721 aaggaacgta tcatcattac aaagggtggt gctgaccgca atacaagtat taagaacatc
     3781 attgaagcca ttgatgctta tcgtccgctt actccagagg atatcgttgt tacccacgat
     3841 tctgttcgtc catttattac acttcgcatg attcaggaca atatccaact tgcccaaaat
     3901 catgacgcag tggacacagt ggtagaagcg gttgatacta tcgttgaaag taccaatggt
     3961 caatttatta cagatattcc aaatcgtgct cacctttatc aaggacaaac acctcaaaca
     4021 ttccgttgca aggacttcat ggacctttat ggatctcttt ctgatgaaga gaaggaaatc
     4081 ttgacagatg catgtaaaat ctttgtgatc aaaggaaaag atgtggcttt ggccaaaggt
     4141 gaatactcaa atctgaagat tacaaccgta acagatttga agattgcaaa aagtatgatt
     4201 gagaaagact agtaaaatga ttaatcaaat ttatcaacta actaagccta agtttatcaa
     4261 tgtcaaatat caggaagagg ctattgacca agagaatcat atccttatcc gtcccaacta
     4321 catggctgtc tgtcatgcgg atcagcgtta ctatcaggga aaacgtgatc ccaagatttt
     4381 gaataaaaag cttccaatgg caatgattca cgagtcatgt ggaaccgtca tttctgaccc
     4441 gaccggaacc tacgaggttg gtcaaaaagt tgtcatgatt cccaatcagt ctcctatgca
     4501 gagtgatgaa gaattctatg aaaactacat gacagggacc catttcttgt ctagtggatt
     4561 tgatggcttt atgagagagt ttgtttctct ccctaaagat cgtgtggtgg cttatgatgc
     4621 tattgaagat acggttgcag ccattacaga gtttgtcagt gtgggcatgc acgctatgaa
     4681 tcgtctattg actcttgctc atagcaagcg ggagcggatc gccgttattg gagatggaag
     4741 tttagctttt gtggttgcca atattatcaa ctatactttg ccagaagcag agattgtggt
     4801 tattggtcgt cattgggaaa agttggaact cttctcattt gccaaagaat gctatattac
     4861 ggataatatt cctgaagatt tggcctttga ccatgctttt gaatgttgtg gtggtgatgg
     4921 tactggacca gctattaatg acttgattcg ctacattcgt cctcagggaa cgattctcat
     4981 gatgggagtt agcgaatata aagtcaatct caatactcgc gatgccttag aaaagggctt
     5041 gctcttggtt gggtcatctc gttctggtcg cattgatttt gaaaatgcta tccaaatgat
     5101 ggaagtcaag aaatttgcca atcgtcttaa aaatatcctt tatctagaag aacctgtaag
     5161 agaaattaaa gatattcatc gtgtctttgc aaccgattta aacacagcct ttaaaacagt
     5221 gtttaagtgg gaagtataag tactggaggt taattgtgga gaaaatcatt aaagaaaaaa
     5281 tttcttcctt acttagtcaa gaagaggaag tcctcagtgt tgaacaactg ggtggaatga
     5341 ccaatcaaaa ctatttggcc aaaacaacaa ataagcaata cattgttaaa ttctttggta
     5401 aagggacaga aaagcttatc aatcgacaag atgaaaagta caatcttgaa ctactaaagg
     5461 atttaggctt agatgtaaaa aattatcttt ttgatattga agctggtatc aaagtaaatg
     5521 agtatatcgg atctgcgatt acgcttgatt caacgtcaat caagaccaag ttcgacaaaa
     5581 ttgctccaat attacaaact attcatacgt ctgctaagga attaagagga gaatttgctc
     5641 cttttgaaga aatcaaaaaa tacgaatcct tgattgaaga acaaattcct tatgccaact
     5701 atgaatctgt tagaaatgca gtcttctcct tagagaaaag actggctgac ttaggtgttg
     5761 acagaaaatc ttgtcatatc gatttggtgc ctgaaaactt tatcgaatca cctcaaggac
     5821 gactttattt gattgactgg gaatattcat caatgaatga tccaatgtgg gatttggctg
     5881 ccctcttttt agagtctgaa ttcacttccc aagaggaaga aactttctta tctcactatg
     5941 agagtgacca aacaccggtt tctcatgaaa agattgctat ttataaaatt ttacaagata
     6001 ctatttggag tctatggact gtatataagg aagagcaagg tgcagatttt ggtgactatg
     6061 gtgtgaatcg ttaccaaaga gctgttaaag gtttggcttc ttatggagga tcagatgaaa
     6121 agtaaaaacg gagttccttt tggccttctc tcaggtattt tctggggctt gggtctaacg
     6181 gttagtgctt atatcttttc gatttttaca gatttgtcac cctttgtggt ggctgcaact
     6241 catgattttt tgagcatctt tatcttacta gcttttctct tggtaaaaga agggaaagtt
     6301 cgcctctcaa ttttcttaaa tattcgcaat gtcagtgtta tcatcggagc cttgctagca
     6361 ggccctatcg gtatgcaggc caatctttat gcagttaagt atatcggaag ttctttagct
     6421 tcatctgtat cggctattta ccctgcgatt tcagttctat tggctttctt ctttttgaag
     6481 cacaagattt cgaaaaatac tgtatttggg attgtcttga ttattggagg gattattgct
     6541 cagacctata aggttgaaca ggttaattct ttctacattg ggattctttg tgctttggtt
     6601 tgtgctattg catggggaag tgagagtgtt cttagctctt ttgccatgga aagtgaattg
     6661 agtgaaatcg aagccctctt aatccgtcaa gtaacttcgt tcttgtccta tcttgtgatt
     6721 gtgctcttct ctcatcagtc atttactgca gtagccaatg gacaattgct aggtctcatg
     6781 attgtttttg cagcctttga tatgatttcc tacttggctt attatatcgc tatcaatcgc
     6841 ttgcaaccag ccaaggctac aggcttgaac gtgagctatg tagtatggac ggtcttgttt
     6901 gcagttgttt tcttgggtgc accgctagat atgctgacca ttatgacgtc acttgtcgtc
     6961 attgctggag tttatattat tattaaagaa taaaggagat tcgtgtgaaa gccattatct
     7021 tagcagcggg attgggaact cgcttgcgtc ctatgactga aaatacccct aaagccttgg
     7081 ttcaggttaa tcaaaaacct ttgattgagt accaaattga gtttctcaaa gaaaaaggaa
     7141 tcaatgacat catcatcatt gttggttatc ttaaagaaca attcgattac ttgaaagaga
     7201 aatacggtgt tcgtctcgtt ttcaatgata aatacgctga ctacaataac ttttactctc
     7261 tctatcttgt aaaagaagaa ttggccaaca gctatgttat tgatgctgac aattatctct
     7321 ttaaaaatat gttccgcaat gatttgacac gttcgactta ttttagtgtt tatcgtgaag
     7381 attgtaccaa cgaatggttc ttggtttatg gagatgacta caaggttcaa gacattattg
     7441 ttgatagcaa ggcaggtcgc atccttagtg gtgtatcctt ctgggatgct ccaactgcag
     7501 aaaagattgt cagctttatc gacaaggctt atgtaagtgg tgaatttgtt gatctctatt
     7561 gggacaatat ggttaaggat aatatcaaag agctagatgt ctatgttgaa gaattagaag
     7621 gcaatagcat ttatgagatc gatagtgtcc aagactatcg taaattagaa gaaattctta
     7681 aaaacgaaaa ttaaagattc caacatctga caaaatagtc ggatgttttt tgatttttta
     7741 cgaactttta cgaatagata gatgagtaga aaaagaaatg gagttattta tgaaaatcac
     7801 aaactatgaa atctataagt taaaaaaatc aggtttgacc aatcaacaga ttttgaaagt
     7861 gctagaatac ggtgaaaatg ttgatcagga gcttttgttg ggtgatattg cagatatctc
     7921 aggttgccgt aatccagccg tttttatgga acgttatttt cagatagacg atgcgcattt
     7981 gtcgaaagag tttcaaaaat ttccatcttt ctctatttta gatgactgtt atccttggga
     8041 tttgagtgaa atatatgatg cgcctgtact tttattttac aagggaaatc ttgacctcct
     8101 gaaattcccg aaggtagcgg tcgtgggcag tcgtgcttgt agcaaacagg gagctaagtc
     8161 agttgaaaaa gtcattcaag gcttggaaaa tgaactggtt attgtcagtg gtctggccaa
     8221 gggcattgac acagcagctc atatggcagc tcttcagaat ggcggaaaaa ccattgcagt
     8281 gattggaaca ggactggatg tgttttatcc taaagccaat aaacgcttgc aagactacat
     8341 cggcaatgac catctggttc taagtgaata tggacctggt gaacaacctc tgaaatttca
     8401 ttttcctgcc cgtaatcgca tcattgctgg actttgtcgt ggtgtgattg tagcagaggc
     8461 taagatgcgt tcaggtagtc tcattacgtg tgagcgagca atggaagaag gacgcgatgt
     8521 ctttgctatt cctggtagca ttttagatgg actatcagac ggttgccatc atttgattca
     8581 agaaggagca aaattagtca ccagtgggca agatgttctt gcggaatttg aattttaaaa
     8641 atgacctaag ctagaattct aagaaaaaat caattttaag agaaaatgaa cccaacattt
     8701 ccataataaa acgcatatta gcaagttttt aacacttgat aatatgcgtt ttttctaagt
     8761 ggattagtag agtagaggat ttttctcata taatactctt cgaaaatctc ttcaaactac
     8821 gtcagcttcc atctgcaacc tcaaaacagt attttgagct gacttcgtca gtcttatcta
     8881 caacctcaaa gcagtgcttt gagcaacctg tggctagctt cctagtttgc gctttgattt
     8941 tcattgagta taagggaaag tatagtgaat tgaaataaga tgtgaacaac tctatcagga
     9001 aagtcaaatt gatttataga aatattttag cagccaaggt gcactgttat agattcaata
     9061 cactataatt tagtgtaatt gagaaaggag aaatgattgt gattgatgtt ggctaggtta
     9121 tgttcaatga ttcctaccgt ctcaaatctt gtcagtaagg aaaaataaat tcttcaaaag
     9181 tagagattac aaggcttgtt taagaaagaa ttcaaagacc ttgacaaata aaaataaaat
     9241 ggttattata aaaaatggtc tgaaatagat gatgatactt ttcgaaaatc tcttcaaact
     9301 acgtcagctc agctttgcct tgctgtgttt tgagcaagct acggttagct tccgagtttg
     9361 attttcattt actagaaatg aaactgatga gagatatcag tagacatttg agtcaggata
     9421 ttatggaaaa tgataaaaag agctcgtgag attggcatat cagactacta aagtattgag
     9481 tttgttagga ttttagcgac tagttagctg ggaaaggaag atatttgtga caaataataa
     9541 actgtattcg ttgatagaat ttagaaataa aatatatgaa gaattagaac tttccagaag
     9601 tgatttagcg attttactat gtgccatgct tatcgcctct atcggattaa atatggattc
     9661 gactcccgtg attattggag ccatgttaat ctctcctttg atgacaccta ttctgggagt
     9721 ggggctctct ctagctatat ttgattttaa attgttaaga aaatctttta aaatattagc
     9781 tattcaaatt cttgccagtc taatagcttc aacactttat ttttatcttt ctcccatttc
     9841 gtatgctagt tcggagattg ttgctagaac ctctccgact atttgggatg ttctcattgc
     9901 ttttgtagga gggatagcag gtattattgg tgctaggaaa aaagagacca ataatattgt
     9961 tcctggtgtt gctattgcaa ccgccttgat gcctcctctt tgtacagtag gttatgctat
    10021 tgcttctgct aatctaaaat ttatcatagg ctcctcttac ctattcctca tcaattgtag
    10081 ctttattgtc attgcgactt atataggtgt taggttgatg atggttaaga aacattattt
    10141 taaagataat gaagaagact ctaaaatgcg taggattttg cttctagttg ctgttttgct
    10201 gatgattccg agtttcatct ctgcaacgac tttagtgaga gaaacgttga aaaaagagtc
    10261 ccttaagaaa tttatatcag agcagtttca ggggtataat attttgaaaa aaacctattc
    10321 taaaaagact cataccctaa agctaaccat ttcaggaaat tatttgacag aagaagaact
    10381 cgatatgatt tcaagtaaga gaggtgacta tggtttaagt gatgtttctg ttcaagtttc
    10441 acaattgtct gattcagaac aacttagtaa ggaagagctg gtggagtatt tcttccagta
    10501 tatcaaggat aaggaagcaa aagaaaagga gaaagccaat aaatttgata cagagtctga
    10561 ggagcaataa tttcttgaga atagctggtt tctctcgtga gtcttctatg tatatcaaag
    10621 gaagactgag gttttaagta taaaactttt cttctattat agtagctaag tcttgacagg
    10681 gttcaaaaaa tggtttacac tttataaagt ttattacttt gaaaaggtgt gatactgtgg
    10741 ctacggcaac aaaaaagaaa aaatcaacag ttaaaaaaaa tctagtcatc gtggagtcgc
    10801 ctgctaaggc caagacgatt gaaaaatatc taggcagaaa ctacaaggtt ttagccagtg
    10861 tcgggcatat ccgtgatttg aagaaatcca gtatgtccgt cgatattgaa aataattatg
    10921 aaccgcaata tattaatatc cgaggaaaag gccctcttat caatgacttg aaaaaagaag
    10981 ctaaaaaagc taataaagtt tttctcgcga gtgacccgga ccgtgaagga gaagcgattt
    11041 cttggcattt ggcccatatt ctcaacttgg atgaaaatga tgccaaccgt gtggtcttca
    11101 atgaaatcac caaggatgca gtcaaaaatg cttttaaaga acctcgtaag atcgatatgg
    11161 acttggtcga tgcccaacaa gctcgtcgga tcttggatcg cttggtaggg tattcgattt
    11221 cgcctatttt gtggaagaag gtcaagaagg gcttgtcagc aggtcgcgtt cagtccattg
    11281 cccttaaact catcattgac cgtgaaaatg aaatcaatgc cttccagcca gaagaatact
    11341 ggacagttga tgctgtcttt aaaaagggaa ccaaacaatt tcatgcttcc ttctatggag
    11401 tagatggtaa aaagatgaaa ctgaccagca ataacgaagt caaggaagtc ttgtctcgtc
    11461 tgacgagtaa agacttttca gtagatcagg tggataaaaa agagcgcaag cgcaatgctc
    11521 ctttacccta taccacttca tctatgcaga tggatgctgc caataaaatc aatttccgta
    11581 ctcgaaaaac catgatggtt gcccaacagc tctatgaagg aattaatatt ggttctggtg
    11641 ttcaaggttt gattacctat atgcgtaccg attcgactcg tatcagtcct gtagcgcaaa
    11701 atgaggcggc aagcttcatt acggatcgtt ttggtagcaa gtattctaag cacggtagca
    11761 aggtcaaaaa cgcatcaggt gctcaggatg cccatgaggc tattcgtccg tcaagtgtct
    11821 ttaatacacc agaaagcatc gctaagtatc tggacaagga tcagctcaag ctatataccc
    11881 ttatctggaa tcgttttgtg gctagccaga tgacagcggc cgtttttgat accatggctg
    11941 ttaaattgtc tcaaaatgga gttcaatttg ctgccaatgg tagtcaggtt aagtttgatg
    12001 gttatcttgc catttataat gattctgaca agaataagat gttaccggac atggttgttg
    12061 gagatgtggt caaacaggtc aatagcaaac cagagcaaca tttcacccaa ccgcctgccc
    12121 gttattctga agcaacactg attaaaacct tagaggaaaa tggggttgga cgtccatcaa
    12181 cctatgcgcc aaccattgaa accattcaga aacgttatta tgttcgcctg gcagccaaac
    12241 gttttgaacc gacagagttg ggagaaattg tcaataagct catcgttgaa tatttcccag
    12301 atatcgtaaa cgtgaccttc acagctgaaa tggaaggtaa actggatgat gtcgaagttg
    12361 gaaaagagca gtggcgacgg gtcattgatg ccttttacaa accattctct aaagaagttg
    12421 ccaaggctga agaagaaatg gaaaaaatcc agattaagga tgaaccagct ggatttgact
    12481 gtgaagtgtg tggcagtcca atggtcatta aacttggtcg ttttggtaaa ttctacgctt
    12541 gtagcaattt cccagattgc cgtcataccc aagcaatcgt gaaagagatt ggtgttgagt
    12601 gtccaagctg tcatcaggga caaattattg agcgaaaaac caagcgtaat cgcctcttct
    12661 atggttgcaa tcgctatcca gaatgtgaat ttacctcttg ggacaagcct gttggtcgtg
    12721 actgtccaaa atgtggcaac ttcctcatgg agaaaaaagt ccgtggtggt ggcaagcagg
    12781 ttgtttgtag caaaggcgac tacgaggaag aaaagattaa ataagaggag gggcccgaaa
    12841 gtaaatttca ggctcttttt ggttagaact tgacaaaata catcatttta tgcgaaacta
    12901 gaagaagatt attttaacta ggagaagtta tgcgtcttat ctatctgata attggttttt
    12961 tatcactggc cttggctatt gttggggttg ttttaccctt gttgcctaca acacctttcc
    13021 ttttgttgtc tattgcttgt ttctccagaa gttccaagcg attcgaagac tggctttatc
    13081 ataccaagct ctatcaaaca tatgtagctg attttcgcga gactaagtct attacgcgtg
    13141 aacgaaagaa aaaaatcatc gtatccattt acattttgat ggggatttct atttattttg
    13201 cccctctctt accagtcaaa atcggtctgg gtgctttgac catctttatc acttattatc
    13261 tcttcaaggt cattccagac aaagaatagt taaaacagta gttatttacc ttgataaaat
    13321 tgaaagcata ttcataacaa tatgatataa taaatttgaa gtaatattca aggagaatca
    13381 aatgatttac gaattttgtg ctgaaaatgt gactttactt gaaaaagcga tgcaggctgg
    13441 agctcgtcgg attgaactct gtgataatct agcagttggt gggacaacac ctagctatgg
    13501 agtgactaag gcagcggttg aactggcagc taactacgat acaaccatca tgaccatgat
    13561 tcggccacgt ggtggtgact ttgtctataa tgacctagaa attgctatca tgctagaaga
    13621 catttgtttg actgctcagg ctggaagtca aggggttgta tttggagctt taactgctga
    13681 taaaaagttg gataagccta atctggaaaa gttaattgct gcatcaaaag gaatggaaat
    13741 tgtctttcac atggcctttg atgaactaag tgatgaagat caaccggaag ctattgactg
    13801 gctcagtcaa gccggtgtca ctcgtatcct aactcgtgct ggtgtgtctg gcgactcctt
    13861 agaaaaacgt tttgttcact atcacagaat tttggagtac gctaaaggta aaattgaaat
    13921 tctaccaggt ggggggattg accttgacaa ccgtcaaacc tttattgacc aggtgggggt
    13981 aacacaattg catggtacta aggttgtttt ttaaaaaata gaaaggaact gctagccttg
    14041 ggtagcagtt ttcacttatg tttgaaattt ttaaatccta tcaatttaat caagaaaagg
    14101 ctcatgatta tggttttata gaaaatagcg aagtctggac atatagttgc cagattttgc
    14161 aaggtgactt tgtcatgact gtgtccatca ctgctgataa tgtgaacttt caagtctttg
    14221 accaagagac tggtgacctc tatcctcacg ttcatatgga aagcatgagg ggaagttttg
    14281 tcggaaatgt ccgtgaggct tgtctggaga ttctttacca gattcggaag gcttgttttg
    14341 atgtgcaaga ttttatctgt catcagacta agcgtatcat gactcaagtt caggaaaagt
    14401 atggaaacca gttggagtat ctgtgggaaa aatcgcctga tacagctgta ttgcgccatg
    14461 aaggcaatca aaagtggtat gccgtcttga tgaaaatctc ttggaataag ctggaaaagg
    14521 gcagagaagg acaagtggaa gcagtcaacc tcaagcatga ccaagtagct aatttgcttt
    14581 cacaaaaggg gatttatcca gccttccata tgagcaagcg ctactggatt agtgtgtccc
    14641 ttgatgatac tttatcagat gaagaagtac tggaattgat agaaaaaagt tggaacttaa
    14701 cctctaaaaa atgaaatatt ttaataattt tcatgaactt tcaattagct aaatattctt
    14761 tactgaagaa atttttagaa aatataggat ttaccacact agaggaatat ggtgccatct
    14821 tcaaatacct gattgagaat gtcaagacgg atcgtcagat catctgttcg cctcactgtc
    14881 atgatgacct cggaatggca gtggcaaata gccttgctgc tgtcaagaat ggtgcaggac
    14941 gtgttgaagg gactatcaat ggtattaggg agcgagctga aaatgctgct ttggaagaaa
    15001 ttgcagtggc tctcaatatt cgccaagatt actaccaagt agaaaccagt attgtcctaa
    15061 atgagaccat caatacgtca gaaatggttt ctcgcttctc tggtattcca gttcctaaaa
    15121 acaaagccgt cgttggtggc aataccttct cccacgaatc tggtattcac caagatggag
    15181 tccttaaaaa tcctctcact tatgagatca tcacacctga attggttggt gttaagattc
    15241 cgcttggaaa attatctggt cgccatgctt ttgttgagaa actgagagaa ttggccctag
    15301 attttacaga agaggatatc aaaccactct ttgctaagtt caaggcactg gccgataaga
    15361 agtaagaaat cacagatgca gatcctcgag ctttggtagc tggaaccatg gttgaaaatc
    15421 cagaaggctt ccactttgat gatttacaac ttcaaactca tgcagataat gacattgaag
    15481 cgctcgttag cctagccaat atggatggtg agaaagtcga atttaatgcg acagggcaag
    15541 gttccgttga agcaatcttt aacgctatcg ataagttctt taaccaatct gttcgtttgg
    15601 tgtcctacac tatcaatgcg gtaacagatg gaatcgatgc ccaggatcgg gttttggtca
    15661 ctgttgaaaa cagagataca gaaaccatct ttaatgcagc agggcttgat tttgatgtgt
    15721 tgaaggcttc tgctattgcc tatataaacg ctaatacctt tgttcaaaaa gagaatgcag
    15781 gtgagatggg acgcagtgtt tcttaccacg atatgcctag tgtgtaaagg agaaggctat
    15841 ggcaaagaaa atagtagctc tagtaggaga cggaattggc ccagaaatca tggaggctgg
    15901 tttagaagtt ctggaggctc tagctgaaaa aacaggtttt gactatgaga ttgacagacg
    15961 accgttcgga ggtgcagata ttgatgcagc aggacctccc ttacctgatg aaacccttaa
    16021 ggcaagtagg gaagcagatg ctatcctact agcagctatc ggtagtcctc agtatgatgg
    16081 agcagcggtt cgccctgaac aaggcctgat ggctctccgt aaggaactca atctttacgc
    16141 taatattcgt cctgtaaaaa tctttgacag tctcaagtat ttgtcaccac tcaaaccgga
    16201 acgaatttct ggtgtagact ttgtcgtggt gcgtgaattg acaggcgaga tttactttgg
    16261 agatcatatt cttgaagagc gcaaagcgcg tgatatcaac gactatagct atgaggaagt
    16321 ggagcggatt attcgcaaag cctttgaaat tgcaagaaat cgcagaaaaa tcgttactag
    16381 tatcgataag caaaatgttc tagcgacctc aaaactctgg cggaaagtag ctgaggaagt
    16441 cgcacaggat ttcccagatg taaccttgga acaccagctg gtagactcag ctgctatgct
    16501 tatgattacc aatcctgcta agtttgatgt tattgtaacg gagaatcttt ttggagatat
    16561 tttatctgat gaatcaagcg tcttatctgg tacacttgag gttatgccat cagccagtca
    16621 ttctgaaaat ggaccaagtc tctatgaacc tattcacggt tcagcacctg atattgcagg
    16681 tcaaggaatt gccaatccta cttccatgat tttatcagtt gccatgatgt tgagagatag
    16741 tttcggacgt tatgaggatg cagagcgtat caaacatgct gttgagacaa gtctggcggc
    16801 aggaatttta acgagagata taggaggtca ggcttcaaca aaggaaatga cggaagctat
    16861 tattgcaagg ttatgaagtt agacgaaaaa attactctag tccttttgat ttggaatgtc
    16921 atcattttct tgatttatgg cattgacaaa ttcaaggcaa gaagaagaac ttggcgcatc
    16981 caagagaaaa tcttactcat tttagccctt acttgtggtg gttttggggc ctggttagct
    17041 ggaatcactt ttcaccacaa gactcgaaaa tggtacttta aaacagtttg gtttcttggg
    17101 atggtgacca cactagtagc cttatatttt atttggaggt aatggatggc agggtcttcg
    17161 agggaacacg ctgcttgggt tctagcggac tatggtttta aggtcgtgat tgcaggatct
    17221 ttcggtgaca ttcattacaa taatgaactc aataatggcc tgttgccaat cgttcagcct
    17281 agagaggtta gagagaaact agcccagcta aaaccaaccg accaggtaac tgtggacttg
    17341 gaacaacaaa aaatcatctc accagttgaa gaattcacct tcgagataga tagcgagtgg
    17401 aaacataaac tcctaaatag tttggatgat atcggtatta ccttgcagta tgaagagttg
    17461 attgctgctt atgaaaaaca acgaccagcc tactggcagg attagaaaaa atagaaaagg
    17521 aaatatagta aactgaaata agatgtaaac aaatgaatta gagcttaaca tccatttcca
    17581 gcaatttttt agaaactaca gtggactatt ctggattcaa cacattataa aattatgaca
    17641 aaacacattc acaagaaggc tacgacattt taaaaggtga gggcggatgt atcgtttgcc
    17701 ctactaaagt tggttacatt atcatgacca gcaacaaggc aggacttgag cgtaagttcg
    17761 cagccaaaga acgtaagcgt aacaaaccag gtgttgttct ctgcggtagc atggatgaac
    17821 ttcgcgcttt agcgcaactc aacccagaaa ttgaagcatt ctactaaaaa cattggatga
    17881 agatattctt cttggttgta tccttccttg gaaaccagaa gcctttgaaa aactcaaagc
    17941 atacgggaat ggccgtgaag aacttatgac tgatgtacgt ggtactagct gttttgttat
    18001 caagtttgga aaagcaggtg aacaattggc tgccaagctt tgggaagaag gtaaaatggt
    18061 ctacgcctca tatgcttcaa tgacaaaacg attgaaactc gctatgagag caaggtgtaa
    18121 tggtgtctat ggtcgataag gacggcaaac tcatcccaga acaaggagga gcacgttcaa
    18181 cttcaccagc accagttgtg atccgtaaag ggcttgacat tgataaaatc atgatgcacc
    18241 tgtcagatac ttttaactca tgggactacc gtcaggttga gtattattaa gataaaaaaa
    18301 gaagtctagt gttatgagat attaaagctc ctaacactgg actttttgtt tagaatttct
    18361 tttctttttc tataggatat ggtattctat gtagaaaata tatgttaata agtaatgcca
    18421 atatttaaac atcattagta aaaggagtta gattgatgaa taaaagaaaa gttagtttag
    18481 aagattttta taaatggtat agtctaaata aagaagagtt attaaataag gcaactgttg
    18541 gtgaaaagtt taatgataaa ttaaaagaag agtttctcca ggaatggcct ttggatagga
    18601 ttttaacaat gtcaatcgat gaatatgtaa taggaaaggg acagcaaaat aagtctttat
    18661 gctacgctct tgagaaggga aaatacaaaa atctatttct tggaatttct ggtggctcag
    18721 cttcaaaatt tggtatttat tggaataaaa aaacaaacaa atataaagat caagctaata
    18781 atgagatttc agagttggat cagcgatttt caaaattaaa atcagatttg tatgaaatta
    18841 tcaaagaagg tattcgtttt aactttgaaa atcctatttt tgatatgaaa agatcaacaa
    18901 atgaatttat tggtcgttct gctatggtga caaaattact ttgtatctat actgagggag
    18961 atcctttctt tggtgtaaat attaatagtc agaaagaatt ttggaaccac tttgtttctc
    19021 agacaaatca aggtggacct tatctgcaaa atcataaaat aattgaacta gtgtccaaaa
    19081 cttatcctga gttggagcca tcgaaattag gaactatgct ttttgagtat tctaagcttt
    19141 ttatggaaaa taaggaagac aatagtacaa tggattcatc aaacaatttt cgtcatcaat
    19201 taactcaatc tctattaaag tctccaaacc tcatcctccg tggtgctcct ggcacaggaa
    19261 agacttatct tgctaaagaa attgccaaag aattaacgga tggcaacgaa gaccaaatcg
    19321 gatttgtaca atttcaccca tcctatgatt atacggattt tgtagaaggt ttaagaccag
    19381 tatcaaatgg ggatggagct attgagttta ggctacagga cggtattttt aaagattttt
    19441 gtcagaaagc aaaagaaacc caattgattg gaggacaaga taattttgat gaggcttggg
    19501 attcttactt agaatatata aatgttgctg aagaaaaaga atatataaca aaaacatctt
    19561 acttatctat taatagtaga caaaatttgt cagtaaatta tgatagtggt gtttcaggat
    19621 ggtcactacc tagcaaatat gtttacgagt tgtataaaga taaaaattat aataagcaag
    19681 aatactacaa aagtggtgga aaaactgtcc tagaaacatt gagaaagaga tttggtttga
    19741 aagactatgt ttccccaaca gaaattgata ctgataagaa attcgtcttc atcatcgatg
    19801 aaatcaatcg tggggagatt tctaagattt ttggcgaact ctttttctct atcgaccctg
    19861 gctatcgtgg tgaaaaagga agtgtttcta cccaatatgc aaatctacac gaaactgatg
    19921 aaaagttcta tatccccgaa aatgtttaca tcatcggaac tatgaatgat attgatcgtt
    19981 cagtggatac ctttgatttt gctatgcgtc gtcgttttcg ttttgttgaa gttactgccg
    20041 agggtcaagt tggcatgttg gataaagagc tgaatatcca tgcagaagaa gcaaaaattc
    20101 gtctaagaaa cttgaacgct gctatcgaaa atgttcagga attaaacagt cattatcata
    20161 ttggaccaag ttattttctt aagttgaagg atgtagattt tgactatgaa ttactctggt
    20221 ctgattatat taagcctctc ctagaagact acttgcgagg ttcttatgat gaggttgaaa
    20281 ctttggaaac tttgaaaaaa gcatttgaac tgacaaataa tgatcaaact ggtcaacaag
    20341 atactggtga taatgatgcg gattactgat aatcaataca agattattaa agaaaaattt
    20401 gttgaagaat atcctaaact aagcaatctt cttttagaca gaaccttgga aagtctatcc
    20461 caagatgaac gtattttcat ttttccaaat gatttgactc atactcctga tttggataag
    20521 gaccaaaaga tttttgaaac agtcaatcag aaaatcaaga cagggaacgt gattggtttt
    20581 cttggatatg gtcaggaaag attaacgatt tcctcacgat tttctgatga gagtaatgac
    20641 cattttttgc attatctctt aaacaaggtt cttcatatca atctcactag tttagatgtt
    20701 gctttgtctc gtgaagagag gctttatcaa cttttgatgt atctcttccc caagtatcta
    20761 caagctgcta ttcgaaaagg tctttataag gaataccaga gattttctca taacgacagt
    20821 catgttaagg gagtgattga tgtaagaaac catctcaaga aaaatcttcc tttcacggga
    20881 aatattgcct acacaacgag agagttcacc tatgataatc ccctcatgca gttggtccgt
    20941 cacactattg aatacattaa gaatcagaaa agcattggtc aaggggtact agataatctc
    21001 tcaactagtc gtgaaaacgt atctgaaatc gtgcgtgtaa cgccctctta taaactagct
    21061 gatcgtgcta agattattcg gggaaatcaa tctaaaccta tacgtcatgc atactttcac
    21121 gagtacagaa acttacaaga actttgtctg atgatcctaa accaagaaaa gcacggttta
    21181 gggtatcaag atcaaaaaat ctatggtatt ctctttgatg ttgcctggct ttgggaagag
    21241 tatgtttaca ccttgttgcc aaaaggtttt gtacatccca gaaataagga taagacggat
    21301 ggaatttcag tattttctgt tgggaaacga aaagtatatc cagattttta tgacagagaa
    21361 cgaaagattg ttctagatgc aaaatataaa aaactggaat tgactgaaaa aggaatcaac
    21421 cgtgaggact tattccagct gatttcctat tcttatattt taaaagctga gaaggctgga
    21481 cttgtttttc cgagcaagga caaggttatt gataatgaga tgggaaacct agcaggttat
    21541 ggagctttgt tgaagaaatg gtctatccaa attcctcaga agtcttcatc ttatagtgca
    21601 ttttgtaaaa tgatggaaaa ttcagaagaa aattttaaag cgattattga tgaagaagtg
    21661 gggagaaaat aatttcctct ctttctttta tttttaacac aagtaaaacc cgaacaatat
    21721 atttcaattc ataaaataat ttgacaaaaa ctgtactttg gtttataata aattaaggaa
    21781 acgtcggaaa agacgtagtg atgcgagagc ataggtaggt cattacaaaa gaaacgagac
    21841 atcgatatgt taaatgaatt tccaattttt gattacgaag atattcaatt gattccaaat
    21901 aaatgtgtca ttaaaagccg tgcagaagcg gatacaagtg tcactttagg aaatcacacc
    21961 tttaaactac ctgttgtgcc agcgaatatg cagacgattt tggatgaaaa tgtagcagag
    22021 caactggcta aaggtggtta cttctacatt atgcaccgtt ttgatgaggc aggacgcatt
    22081 ccttttatta aacgaatgca cgatcaaggg ctcattgctt ctatctctgt cggtgttaag
    22141 gactatgagt atgatttcgt tagacagctc aagactgatg ctcctgagta tatcactatt
    22201 gatattgctc atggtcatgc ggatagcgtg atttctatga ttcaacacat caagaaagaa
    22261 ttgccagata cctttgtcat tgctggaaat gtgggaacac cagaagctgt gcgtgaattg
    22321 gaaaatgctg gtgcggatgc tactaaggtc ggaatcggtc ctggtaaggt ttgtatcacc
    22381 aaggttaaga ctggttttgg tacaggtggt tggcagttgg ctgctctacg ctggtgtgcc
    22441 aaggctgcgc gtaaaccgat tatcgctgat ggaggaattc gtactcacgg tgatattgcc
    22501 aagtctatcc gcttcggtgc tagcatgatc atgattggtt ccctctttgc aggacacatt
    22561 gaaagtccag ggaaaacgat tgaagtcgat ggtgaacagt tcaaagaata ttatggttca
    22621 gcctcacaat atcagaaagg tgcttacaaa aatgtggaag gcaaacgtat cttgcttcct
    22681 gctaaaggtc atctgcaaga cactttaact gagatggaac aagaccttca aagtgctatt
    22741 tcttatgcag gtggacgtca ggttgctgac cttaaacacg ttgattatgt gatcgtgaaa
    22801 aactcaatct ggaatgggga tgcttcccac taagacgggg tctttgacta aaaaacttgt
    22861 tattagagca aatttctgtt ataataaaac aagtttccac ccttagtgta atggatatca
    22921 cgtaagattc cggttcttga gatgggggtt cgattccctc agggtggatg taaacatcct
    22981 aaaaagcctt taatagggct tttttcttta cactgctcta aatttgccgc taaaactgag
    23041 aatctctgtc taaagaattc ccaaatgctt tccagtcccg ttttagagtg actcaggggg
    23101 ctttttttga tataataaaa aggactgtta tcagttagaa agaggttggt atgaaagaat
    23161 tacaaactgt actaaagaac cattttgcaa tcgaatttac agacaaaaat ttactggaaa
    23221 ctgcctttac tcatacgagt tatgccaatg agcaccgcct cttaaaaatt tcacacaatg
    23281 aacgcttgga atttttagga gacgctgttc tacagttatt gatttcagaa tatctgtata
    23341 aaaaatatcc taaaaagcct gaaggtgacc tatcaaaact ccgtgctatg attgtccgtg
    23401 aggagagttt agctggtttt gcgcgtgatt gccagtttga ccagtttatc aagttgggta
    23461 aaggggaaga aaaatcaggt ggtcgcaatc gtgacaccat tcttggtgat gcctttgaag
    23521 cctttcttgg tgcccttctt ttggataagg atgtggccaa ggtcaaggaa tttatctatc
    23581 aagtcatgat tcctaaggtt gaagcaggcg agtttgagat gattacagac tataaaacct
    23641 atctccaaga gttgcttcag gtcaatggtg atgtggctat tcgttatcag gtgatttctg
    23701 aaacagggcc tgctcacgat aaggtctttg atgtagaagt tcttgttgaa ggtaagagca
    23761 tcggtcaagg ccaaggtcgt tctaagaaat tagcagagca ggaagctgcc aaaaatgccg
    23821 ttgagaaggg gctggattca tgtatttaaa ggaaatcgaa attcaggggt tcaagtcttt
    23881 tgctgataag accaaggtcg tttttgacca aggtgtgacg gcagttgttg gacccaatgg
    23941 atctggaaag tccaatatta cagaaagtct gcgttgggct ttgggggagt ctagtgtcaa
    24001 gagtctccgt gggggcaaga tgccggatgt catctttgct ggaaccgaaa gtcgcaaacc
    24061 gctcaattat gcttctgtag ttgtgactct ggataatcat gacggattta tcaaggatgc
    24121 aggtcaagaa atcagggtgg aacgccatat ctatcgtagt ggagatagcg aatacaagat
    24181 tgacggcaag aaagtccgtc tgcgtgatat tcatgacctc ttcttggata ctggattggg
    24241 acgagattcc ttctctatta tttcccaagg gaaggttgag gagattttta attccaagtc
    24301 tgaggaacga cgagctattt ttgaagaagc tgctggagtt ttaaaataca agactcgcag
    24361 aaaagaaacc gagagtaaac tgcagcaaac tcaggataat ctggaccgct tagaggacat
    24421 tatctacgag ttggataatc aaatcaagcc tcttgagaag caagctgaga atgcccgtaa
    24481 gtttttagac ttggaaggac aacgtaaggc tatttattta gacgttctgg ttgctcaaat
    24541 caaggaaaat aaggcagaac tagagtcgac agaagaagag ctggctcagg ttcaagaact
    24601 cttgatgagt tattaccaaa agcgtgaaaa attagaagaa gaaaatcaaa ctcttaaaaa
    24661 gcaacgccaa gatttacagg atgaaatggc caaagaccaa ggcagtttga tggacttaac
    24721 tagtctgatt agtgatttag aaagaaaatt agccctatcg aaactggagt ccgagcaagt
    24781 ggccttgaat caacaggagg cacaagctcg tttggctgct ttggaggata agagaaattc
    24841 actcagcaaa gaaaagtatg ataaagaaag ctctttagct ctgttagagg gaaatctagt
    24901 ccaaaataat caaaaactca atcgtttaga agctgaattg ctggctttct cagacgatcc
    24961 tgatcagatg attgagctct tacgtgaacg ctttgtagct cttttacaag aagaagcgga
    25021 tgtctcaaac cagttgaccc gtattgagaa tgagttggaa aatagtcgtc agctttctca
    25081 aaaacaagca gatcaactag aaaagctgaa agagcaattg gctatagcta aagagaaggc
    25141 tagtcagcaa aaggaagagc ttgaaactgc caaggagcag gttcagaaat tattggctga
    25201 ctaccaagct attgccaagg agcaagagga gcagaaaact tcctatcaag ctcaacaaag
    25261 ccaactcttt gaccgtctgg ataatctcaa aaacaagcag gccagagctc aaagtttgga
    25321 aaatatcctg agaaatcata gtaactttta tgcaggtgtt aagagtgttc tccaagaaaa
    25381 agatcgccta ggtgggatta ttggtgcagt cagtgagcat ctgacctttg atgtttatta
    25441 tcaaactgcc ctagagattg ccttaggggc aagtagccag catatcatcg tagaagatga
    25501 agagtcggca accaaggcta ttgacttcct taaacggaac agagccggtc gtgcaacctt
    25561 tcttccttta accactatca aggcgcgtac gatttctagt cagaaccaag atgctatcgc
    25621 tgtaagccca ggtttccttg ggatggcaga tgagttggtg acttttgata ctagactgga
    25681 agccattttc aagaacttgc tagctacgac ggctatcttt gataccgtag aacatgcgcg
    25741 tgcagcagct cgccaagttc gttatcaggt tcgtatggtg acattggatg ggacagaatt
    25801 acgcacgggt ggttcttacg caggtggagc caatcgtcag aacaacagta ttttcatcaa
    25861 gccagaactg gagcaattac aaaaagaaat tgctgaagaa gaagcaagtt tgcgttcaga
    25921 tgaagtgagt ttgaagaact tgcaagatga gctagctaga ttgacagaaa gattagaagc
    25981 catcaaatct cagggagagc aggctcgtat tcaggagcaa ggcttgtccc tcgcctatca
    26041 gcagaccagt cagcaagttg aagaactgga aactctttgg aaactccaag aagaggaaat
    26101 agatcgtctt tccgagggag attggcaagc ggataaggaa aaatgccaag agcgtcttgc
    26161 tgcaatcgcc agtgacaagc aaaatctgga agctgagatt gaagagatta agtctaacaa
    26221 aaatgccatc caagaacgct atcaaaactt gcaggaagag ctagcgcaag ctcgtttgct
    26281 taagacagaa ctgcaagggc aaaaacgtta tgaagttgct gatattgaac gcttaggcaa
    26341 ggaattggac aatcttgatt ttgaacaaga agaaatccag cgccttcttc aagaaaaggt
    26401 tgataatctt gagaaggttg atacagaatt gctcagtcaa caggcggaag aatccaaaac
    26461 tcagaaaaca aatctccaac aaggtttgat tcgccagcag tttgagttgg atgatataga
    26521 aggtcaactg gatgatattg ccagtcattt ggatcaggct cgccagcaga atgaggagtg
    26581 gattcgcaag caaacacgtg ctgaagccaa gaaagaaaag gtcagcgaac gcttgcgcca
    26641 tctacaaagt caattaacag accagtacca gattagctat actgaagctc tagaaaaagc
    26701 gcatgaattg gaaaacctca atctggcaga gcaagaagtt aaggatttag agaaggctat
    26761 tcgctcactg ggtcctgtca atatagaagc tattgaccag tacgaagaag ttcacaaccg
    26821 tctggacttt ctaaatagtc agcgagatga tattttgtca gcgaaaaatc tgctccttga
    26881 aaccattaca gagatgaatg atgaggttaa ggaacgcttt aaatcaacct ttgaggccat
    26941 tcgtgagtcc tttaaagtga ccttcaagca gatgtttggc ggaggtcagg cagacttgat
    27001 attgactgag ggcgaccttt taacagctgg tgtggagatt tctgttcaac ctccaggtaa
    27061 gaaaatccag tcgcttaacc tcatgagtgg tggtgaaaaa gctctatcgg ctcttgcctt
    27121 gctcttctcc attattcgtg tcaagactat cccatttgtc atcttggatg aggtagaggc
    27181 tgcgctggac gaagccaatg ttaaacgttt tggggattac ctcaaccgct ttgacaagga
    27241 cagccagttc atcgtcgtaa cccatcgtaa gggaaccatg gcagcggctg attctatcta
    27301 tggagtgacc atgcaagaat cgggggtctc aaaaattgtt tcggttaagt taaaagattt
    27361 agaaagtatt gaaggatgac aattaaacta gtagcaacgg atatggacgg aaccttccta
    27421 gatgggaatg ggcgctttga tatggatcgc ctcaagtctc tcttggcttc ctataaggaa
    27481 aaagggattt actttgcggt ggcttcgggt cggggatttc tgtctctgga aaaattattt
    27541 gctggtgttc gtgatgacat tattttcatc gcggaaaatg gcagtttggt agagtatcaa
    27601 ggtcaggact tgtatgaagc gactatgtct cgtgactttt atctggcaac ttttgaaaag
    27661 ctgaaaacgt caccttatgt agatatcaat aaactgctct tgacgggtaa gaagggttca
    27721 tatgttctag atacggttga tgagacctat ttgaaagtga gtcagcatta taatgaaaat
    27781 atccaaaaag tagcgagttt ggaagatatc acagatgaca ttttcaaatt tacaaccaac
    27841 ttcacagaag aaacgctaga agctggtgaa gcttgggtca atgataatgt ccctggtgtc
    27901 aaggctatga caactggctt tgaatctatt gatattgttc tggactatgt cgataagggt
    27961 gtagctattg ttgaattagc taaaaaactt ggtatcacaa tggatcaggt catggctttt
    28021 ggagacaatc ttaatgactt acatatgatg caggttgtgg gacatcctgt agctcctgaa
    28081 aatgcacgac ctgaaatttt agaattagca aagactgtga ttggtcacca taaggaacgg
    28141 tcggttatag cttatatgga gggcttataa tggcagatat aaaattgatt gcattggact
    28201 tggacgggac cttgctgact actgataaaa ggctgacgga tcgtaccaag gaaaccttga
    28261 aagctgcgcg tgatcgtggt atcaaggtcg tattgacaac tggtcgtccc ttaaaagcta
    28321 tggatttctt tctccatgag ctagggactg acggtcagga agatgagtat accattactt
    28381 ttaatggtgg tttggttcag aaaaatacag gtgaaatcct tgataagaca gtcttttcat
    28441 atgatgatgt ggcacgcttg tatgagaaaa cagagaaatt atcactgcca cttgatgcca
    28501 tctcagaagg aacagtttat caaatccaat cggaccaaga aagtctttat gccaaattca
    28561 atccagcttt gacttttgtt ccagttgact ttgaagacct gtctagtcaa atgacctaca
    28621 acaaatgcgt gactgccttt gctcaagaac ccttggatgc agccattcag aagatttctc
    28681 cagaattgtt tgaccaatat gaaatcttta aatcacgtga aatgttgcta gagtggtcac
    28741 caaagaatgt tcataaagca acaggtttgg caaaactaat cagccatctc ggaatcaacc
    28801 aaagccaagt tatggcctgt ggtgacgagg ccaatgacct ttctatgatt gaatgggcag
    28861 gtcttggtgt tgctatgcaa aacgctgttc ctgaagtaaa ggcagccgca aatgtagtaa
    28921 tgccgatgac caacgatgag gaagctgtcg cctgggctat cgaagaatat gtgctaaagg
    28981 agaactaaga tatgggattg tttgaccgtc tattcggaaa aaaagaagaa cctaaaatcg
    29041 aagaagttgt aaaagaagct ctggaaaatc ttgatttgtc tgaagatgtt gatcctacct
    29101 tcacagaagt tgaggaagtt cctcaggaag aagcagaggt tgaaattgtt gaacaagctg
    29161 tgttccaaga ggaggaaatc caagacacag ttgaagaaag tcaggattca gagccagctg
    29221 taggggtttc tcaagaagaa atagaagaat taccaaactc agaagaatta ccagaggaag
    29281 agaagcttga gcacgaagga actgtagaag aaaataattc tgaagttctt gaaccagaaa
    29341 ggcctcaaac agaagaaact gttcaggaaa aatatgaccg cagtctcaag aagactcgta
    29401 cgggcttcgg tgctcgcttg aacgccttct ttgctaactt ccgctctgtt gacgaagaat
    29461 ttttcgagga actggaagaa ctgctgatta tgagtgatgt tggtgtccaa gtcgcttcta
    29521 acttaacgga ggaactacgt tacgaagcca agcttgaaaa tgccaagaaa cctgatgcac
    29581 ttcgtcgtgt catcattgag aaattggttg agctttatga aaaggatggt agctacgatg
    29641 aaagcatcca cttccaagat aacttgacag ttatgctctt tgttggtgtg aatggtgttg
    29701 ggaaaacaac ttctattgga aaactagccc accgctacaa acgaactggt aagaaggtca
    29761 tgctggttgc agcagatacc ttccgtgcgg gtgcagtagc tcagctagct gaatggggcc
    29821 gacgagtaga tgttccagta gtaactggac ctgaaaaagc tgatccagcc agcgtggtct
    29881 ttgatggtat ggaacgtgcc gtggctgaag gtatcgatat tctcatgatt gatactgctg
    29941 gtcgtctgca aaataaggat aaccttatgg ctgagttgga aaagattggt cgtattatca
    30001 aacgtgttgt gccagaagca ccacatgaaa ccttcttggc acttgatgca tcaacaggtc
    30061 aaaatgccct agtacaggcc aaagaatttt cgaaaatcac acctttaacg ggaattgttt
    30121 tgactaagat tgatggaact gctcgaggag gtgtggttct agccattcgt gaagaactca
    30181 atattcctgt aaaattgatt ggttttggtg aaaaaatcga tgatattgga gagtttaact
    30241 cagaaaactt tatgaaaggt ctcttggaag gcttaatcta atcagaagca aaaatcctgc
    30301 aaggtacaaa cttgcaggat ttttttattc gaaacgacca tcttgacgat aggcgatatc
    30361 tggttgccaa gtccatttgg catcgaattt ttcaagtagg tcaaagctgg cttgaggtcc
    30421 catgcttcca gctttatagt catgaagtgg ggcaccattt tcggcccaga gctcttcaat
    30481 acggtcaatc aacttccatg acgcaccaac ctcatcccag tggctaaagt tagttgagtt
    30541 gttatttagg acatcataaa tcaatttctc gtatggttct ggagaagcac cagttgcagt
    30601 cgcgtctgta cgataatcaa gtgagttagg agccaagtta aattcttctc ctacttgctt
    30661 cccatttagg ctaagagaga agccttctgt tggttgaata tagatggtca aaatatttgg
    30721 agcaagtggt tctccaaaga tagaatccat ttgtttaaag acgatgttga catgagttcc
    30781 tttttcagtc agtcgtttac ctgtacggaa aaagaaagga acaccacgga atcgatcgct
    30841 gtctacaaag aaggcaccag atgtaaaggt ttcagttgtt gattctggat tcacatttgg
    30901 ttcgctacga taagagatgt atttcatgcc atcaatctta ccagagcggt attgtccacg
    30961 gataaagtgt tctttgagtt cttcatcagt tggatgatag aggtttttaa agaccttaat
    31021 cttttcagca cgaatctcgt cttttgtgaa gcttgctggt ttgtccatgg cgaggagcga
    31081 aagaagttgt agagtgtggt tttggaccat gtcacggagg gcaccggatt ggtcatagta
    31141 gccaccacgt tcttctacac ccaagcgctc cgcaaaggta atttgaacat tgtcgataaa
    31201 atccttgttc caaacgtttt caaaaatcaa gtttgcaaag cgaactgcaa agatgctttg
    31261 gatcatttcc ttgccaagat aatggtcgat acggaaaatt tgttcttcgt caaatgttgc
    31321 taggagttcg tcattcaact tgcttgcagt tgcgtaatct gtaccaaatg gtttttcaac
    31381 gatcaagcgc tcaaaacctt tgccatcgac aatgttttca gatttgaggt gtttggcaat
    31441 ggttccaaag aactgaggtg ccatagacaa gaagaagagc ttattgtgtt cagcttggta
    31501 tttttcatta agctcagctt gtaattgacg caaagcaata taatgttccg aatcattgac
    31561 atcatggctt tgatagtaga agtggctagc aaattcttgg gcttgctcgg tactatctgc
    31621 caaatcaagg atggactcga caactacaga ttcaaaatat tccttactcc aaggtctacg
    31681 ggcagttcca ataacggcaa agtgcttgga aagattgccg gatttatata gtctaaaaag
    31741 ggaagggtag agcttgcgtt tagccaggtc tccactcgca ccgaaaattg taacaataac
    31801 cttagatgac atctagctac ctaatttcta tttttattcc tagtcttgct aggtatgagg
    31861 aaacctcatt tcataaactt aattctaaca taattttccg aaaaatcaaa aattccaata
    31921 cgaggtagaa aaactgcaag gaaatcctta cagtttgagt ttagacgttt aagaccttat
    31981 ctaagaactc tttcagacga gggtgttgtg ggttatcaaa gatttggtca ggtgttccgt
    32041 cttcaaggaa ctcgccatct gcagtaaaga taacgcggtt ggcaacctga cgagcaaatc
    32101 ccatctcatg ggttacgata atcatggtca tgccttgctc agccaattcc ttcataacgt
    32161 taagtacgtc tccaaccatc tcagggtcaa gggcagaagt tggttcatcg aagagcatga
    32221 tgtctggatt cattgctagg ccacgagcga tggccacacg ttgtttttga ccacctgata
    32281 ggctatctgg attggcatta gctttatctg ctagtccaac cttttcaagc aactccattc
    32341 ccaattcctc agcttcttcc ttagtcatca acttgtgctc aataggagca aaggtgatgt
    32401 tgtccaatac agacatatga gggaagaggt tgaagtgttg gaataccatg ccgatatttt
    32461 cacggacgtg gtcaacattg gttgtttttt cagttaaatc atagccgttc acagtgatgt
    32521 gaccgctagt gacttcttct aaaagattga ggctacggag gaaagttgac ttaccagaac
    32581 ctgaaggacc gatgatacaa acaacatctc cttcatagaa cttagtcgta attcctttta
    32641 ggacttcatt ttttccatag tgcttgtgta aatcatttac atcaattttt aattttgcca
    32701 ttaacgaatc ctcttttcta agcgtttcgc tagtctagtc aaaagtgtga taattacaag
    32761 atagaagata gcaaggattg catacatctt gaaactttgg tagttacgag caatgataat
    32821 cttaccagtt tggaagagtt caaccaaacc gatagcagat acgatagttg tatctttaag
    32881 agcgataacg aattggttga caaagtttgg caacatcaat ttagttgctt gtggcaagat
    32941 aatcttacgc atggtttttc cataagagat acccaagctt cggctggctt ccatttggcc
    33001 aactggaacg gcctgaatac caccacgaac gatttcagcg atataagcag ccgcattgag
    33061 tgagagggca attgttccag ctacaaagtc gttaattggg ctttgttggc ctgtgataga
    33121 ctcgatgaag tttggaattc cccagaagat gaaggctgca agaatcatca atggaatacc
    33181 acgaataacg tcaacgaaaa tctcagagat gacgcgaaga gatttgtatg ggctaacgct
    33241 aaacataccg aagataattc cgatgacaat ggcaatagca aatgagataa gagctagagc
    33301 aagagtgata ccaagaccgc taaggagttg tttgtaattg ttttgaagca agccccagag
    33361 cgttgtttcg tcaacagtac ttgttgaagc agttgaagat tcgctagcta ggtatttgtc
    33421 aagaatcttt tggaattcac cgtttgcttt aaggtttgca agtccgttgt tgaacatttc
    33481 aatcagttct ggatttgctc cttttttaac ggcaaaggct gtttcaccga ttggagttcc
    33541 agagattgga gttttcaatt tttgaccttg gctgatagaa tatttgagaa caggttcatc
    33601 atccataacg gcatcaatgg caccagtatt taaactgtca tacattgaag aaccatcagc
    33661 aaaggttttg attttgtagc cgtatttgct ttgattttct gttaggaagg tttgagaagc
    33721 agttccgttt ttaacaccga ctgtctttcc ttttagatct tcataagaag caatattgct
    33781 tgattctttg acaccaagaa tggtattagc agtgtagtat gattctgaga agtcaaaagt
    33841 tgccttacga gcatctgtga cagacatacc agcgatgata ccatcggctt gaccagcttg
    33901 gacagcactg atagcagcat caaaaccagg gttggtgatt tcaatttcaa aaccttggtc
    33961 tttagcgatt gccttaatca attccatatc aataccagtg tattggttgc ttgaattttg
    34021 gaaaacaaaa ggtgcaaaag aagaatcgct ggcaatgata tatttagcct taacaggaat
    34081 ggcttttaat cctgcgagag tagttgtagt tggcactgct gaagatgatg aagcagtcca
    34141 tttcttgata attttatcaa gactaccatc ttttttcatt tcagacaagg cttggttaaa
    34201 ttcagtaacc aggtgctcgt atttacttcc ttttttcaca ccgaaagcaa aacttcctac
    34261 agcttcacca tccatttcaa tatggaggtc ttgaccttgg ttaatggcat attcgataac
    34321 aggtttgtca tccatcatgg catcgatggc accagcactc aagctgttgt tcattaaatc
    34381 accagtgtca aatgttttaa tagtaaagcc gtatttatct ttgattgttt caaggaaacg
    34441 ttgagcggca gttccgtttt taacaccaac ggttttgcca gttaattggt cgtacttgct
    34501 aattttgtgt gactttgtag tagcaatgac aacttttgta tcatagtaag tatcagacat
    34561 ggtgaagact ttttcacgtt ctttagtctt tgtcatccct gccatgatag cgtcggcttg
    34621 cccagcttga accgcattga ctgctgcgtc aaatccagga taggacatct gaatgttcca
    34681 gcctttaatc tcagcgactt tgttaataat gtcaacatca attcctttat aagtttgatc
    34741 tgaatcttta aactcaaaag gtgcataggc ggtatcagaa acaatcttaa tcgtttctgc
    34801 tttggcaata cctaatgaga aaattgggaa taaaattagc aaaaatgcta gaaatttttt
    34861 cttcattttt agtctccttt tccgaatatt ctctcattat atcagaaaaa gtaaaaaaag
    34921 gcaaattttt atatttttcg tgtcagaaaa tataacatcg attttttcct ttccttgaat
    34981 tgctattaaa aagtgctata ataatagtat atatagaaga aaagaggacg gggatatgaa
    35041 gaacaaaaga atatttaaag acttccaagc ttcaaaaatg agtttaaaca tttacacaag
    35101 ccccttgtta gcctttgttt ttgtcttcat aggagagttt gtggctttta ctttgtatgg
    35161 tattggcttg ttagctctca tcggacttgc tagaaatttt ggagaggctg gtcaaaatct
    35221 tgcaagctac ttgcagacct tgcatcagag cttgacggat aaaacaagtg actttcgttt
    35281 aattttagga ttactggcct ttggttttat tcttaacact gtgttcagat ggacaagaaa
    35341 agttgagaaa agacctattc gaaccttggg attttataga gagaatttcc tcagcaatct
    35401 tctgaaagga tttagtctag gtctggcact ttttcttctg accttgttag gtttggtggt
    35461 cttaggtcaa tatcgtttgg aatccattca cttgaatcct tattctcttg cctttgtcgt
    35521 ctttactatc ccattttgga ttttacaggg gacagcagaa gaagtggtgg cccgtgcttg
    35581 gctacttcct caattggcct caagaaccaa tctaaaacta gctattctta tatctagcct
    35641 gttctttacc ctgcttcata tgggcaattc tggcctcacc cctctatctc tagtaaatct
    35701 ctttttattc ggagttgcca tggctcttta ccttctcaaa actgatacag tttggggtgt
    35761 tgcaggtatt catggtgctt ggaattttgc tcagggtaat ctctttggga ttttagttag
    35821 tggtcaaccg tcaggaacgt ctctgatgac ctttttacca caaggcaatc aagattggct
    35881 atcaggtggt tcttttggca tagaaggttc cattatgaca agtctggtat tactactgct
    35941 gattgtctat cttgccaata aattaaagaa agaaaatgaa aggatgtgac ttcggtccgt
    36001 ccttttcttc gtgaaaatac tataagtatg ctaaaatagg aatagcacat ggagagagga
    36061 ttcttatgat caatcacatt acagataatc aatttaaact agtatcaaaa tatcaaccat
    36121 caggagatca accccaagct atcgagcagt tggtggataa cattgagggg ggagaaaaag
    36181 ctcagattct gatgggggcg actggaacag ggaagaccta tactatgagt caggtcattt
    36241 ctaaagtcaa taaaccaact ctggttattg cccacaataa aactctggct ggtcagctct
    36301 atggggagtt taaggaattt ttccctgaaa atgcagttga gtatttcgta tcctactatg
    36361 attattacca gccagaggcc tatgtccctt ctagcgatac ctatattgag aaggatagtt
    36421 ctgtcaatga cgagattgac aagcttcgcc actcagctac ctcagccctt ttggagcgta
    36481 atgatgttat tgtcgtggcc tcagtctctt gtatctatgg tttgggttcg cccaaggaat
    36541 acgctgatag tgtcgttagt ctccgtcctg gtctagagat ttctcgtgat aaactcttga
    36601 atgacttggt cgatattcag tttgaacgta atgatattga tttccaacgc ggaagatttc
    36661 gcgttcgtgg ggatgtggta gagattttcc cagcttcccg agatgaacat gcctttcgag
    36721 tagaattttt tggagacgaa attgaccgta tccgtgaggt tgaggctctg acaggtcagg
    36781 tattgggaga ggtggatcat ttggcgattt tcccagctac tcactttgtg accaatgacg
    36841 accatatgga agttgccgtt gccaagattc aagcagaatt agaagagcag ttagctgtct
    36901 ttgagaagga aggtaaattg cttgaagccc agcgcttgaa acaacggaca gagtacgata
    36961 tcgaaatgct gcgcgagatg ggctatacaa atggggttga aaattattct cgccacatgg
    37021 atggacggag cgaaggagag cctccttata cgcttctcga ctttttccca gatgattttt
    37081 tgattatgat tgacgagagt catatgacta tgggacaaat aaaaggcatg tacaatggag
    37141 accgttcgcg taaggaaatg ctagtaaatt atggtttccg tttaccgtct gccttggaca
    37201 atcgtcctct ccgtcgtgag gagtttgaaa gccatgtgca tcagattgtt tacgtatcag
    37261 cgacacctgg tgactatgaa aatgaacaga ctgagacggt gattgagcaa atcattcgac
    37321 cgacagggct tttggatcct gaggtggaag tccgtccgac tatgggacag attgatgatc
    37381 tcttaggtga aatcaatgcc cgtgttgaaa agaatgaacg aacctttatc accaccttga
    37441 ccaagaaaat ggcagaggac ttgaccgact atttcaagga aatgggcatc aaggtcaagt
    37501 acatgcactc ggatatcaag accttggaac ggacggagat tatccgtgat ctccgcttgg
    37561 gtgtctttga tgtcttggtt ggaatcaatc tccttcgtga agggattgac gttcctgagg
    37621 ttagcttggt tgccattctc gatgctgaca aggaaggttt ccttcgtaac gagcgtggac
    37681 tcatccagac cattgggcgt gccgcccgta acagtgaagg tcatgtcatc atgtatgcag
    37741 atacggttac ccagtctatg caacgtgcta tcgatgaaac tgcccgccgt cggaaaattc
    37801 agatggccta taatgaagag catggtatcg taccacagac aatcaagaaa gaaatccgtg
    37861 acctgattgc cgtgaccaag gcagttgcta aggaagagga caaggaagtc gacatcaata
    37921 gcctcaacaa acaagagcgc aaagaactcg tcaagaaact agaaaaacaa atgcaagaag
    37981 ccgtcgaagt gcttgacttt gaattggcgg ctcagatccg tgatatgatg ttggaagtca
    38041 aggccttgga ttaggggaat tagtatgatt tatttaagaa agttaaagaa agaagatttg
    38101 atgtctttat gggaaatggc ttattcacag cttaatccag tttggaaaca gtatgatgct
    38161 ccctattatg atgattatca gtatttttca aattttaaag aattcgaact acaaaaatca
    38221 gaatccattt taagcaactc aaatcgcctt ggtatttttg ttgatgataa actagttggg
    38281 actgtttcgc gttattgggt atgtaaagaa acaagatgga tggaattggg aattggtatt
    38341 tatgataaaa aattctggaa cactggtatt gggaaagttg ctatgttgca gtggatagat
    38401 aggacgtttc aggattactt ggagttggag catctggttt tgacaacttg gtcaggaaat
    38461 cttggtatga tgaaacttgc tgaaaaatta agaatgaaaa aagaagctca tattccaaaa
    38521 gttcgttatt atcaaggtaa atattttgat agtattaaat atggtatttt gagagaagac
    38581 tgggagaaaa taaatgacgg ttattatcaa atcaatggaa actcctgaag agatagaagg
    38641 caaatccctc gttcactggc aaacgtggag agagtcttat gatgaccttt tgcctgcgga
    38701 atttcaggat acaatgacat tagaaagatg tcgattcttt agtcaaaagt atccagaaaa
    38761 tacattgatt gcgatggatg gcgtgaaggt ggttggtttt atcagttatg gcaattttcg
    38821 tgatgagact attcaagctg gtgaaattat tgctttatat gttttaaaag actattatgg
    38881 aaaaggtatc gcacaaaagt taatgaaagc agctttgact gctcttaatc atttttctga
    38941 aattttctta tgggtattga aagataacaa gcgcgccatt gctttctatc aaaaaatggg
    39001 ttttactttt gatggacaag aaaaaatact tgaacttgga aagcctataa aggaaaaacg
    39061 aatggtgttc tattctaaat aattttaaaa aagtaaaaga taatatctct ggtagtaagt
    39121 ctgaaaattt aataaattag aaagcgagta aatttatgtc ccgttcccaa ttaacaattt
    39181 taacaaatat ctgtctgatt gaagacctcg aaactcagcg cgtggtgatg cagtatcgcg
    39241 cccctgaaaa caatcgctgg tctggttatg cctttcctgg aggtcatgta gaaaatgatg
    39301 aggcttttgc ggagtctgtc attcgtgaaa tctacgaaga aacagggttg actatccaaa
    39361 atcctcaact tgtcggcatt aaaaattggc cactagatac aggtgggcgc tatattgtca
    39421 tttgttataa ggcgactgag ttctctggta cccttcaatc ttcagaagag ggagaagttt
    39481 cttgggtgca aaaagaccag attccaaact taaatctggc ctatgatatg ctaccattga
    39541 tggaaatgat ggaagctccc gacaagtcag agtttttcta tcctcgccgt acagaagacg
    39601 attgggaaaa gaaaatcttc tagtctttta ctaaataacc tagctgatcc aaggcctcct
    39661 cgatatagtg gaggtcttgt tgtgtttcgg cttcgactag gtggtaatgg atgccatctg
    39721 tcaattcaga tagaggtcta aagtcagaat gctcgacttg ttctagaaaa tgttgcacat
    39781 ctctgcgaca agacagttta agcaaggttt caatttctcc ataaacggga tggtcaatca
    39841 aggtattctg gacatgccca ccattatcga caatagcaag gagttcctga ccgatttctt
    39901 caacttcatg tttcactttg aaaagtttgt gaacataagg attggtatca atttgcttat
    39961 agatgtagcc acgattggtg gataggatag gagcgccatc ggctctcaaa attgcaatgt
    40021 cctgcacaat gacctgacgt gtgacatgaa aatgttccgc caaactttgg ccattaaggg
    40081 ctttaggagc ttctttcaag agttggagca gggcttgttt gcgatctttt gtcatagctt
    40141 ttccttttaa cggcgttttc gaagcacttt atagacagct agtgctaatg tatagtctac
    40201 catactatgg ataattgtgc caaatccaac tagtacaaat agaacataga acatattttc
    40261 tacattggta cccgaagttg cgtaaaaaag gacacaggct aatacttcag caagggcatg
    40321 aacaacagcc aaaacaaaat tgaaaaccca ggaagatttt ggtttatcta gggtatcggg
    40381 gaatttttgt aggtaaagag ctcctaaagc accaaaagat atatgggaaa aagcccgaaa
    40441 aacgataacc atgggatagc cagccatcaa aaatccaaaa ctagaggcta ggatgacaaa
    40501 aactgccatc aagggcgaca agaacatggc tataaaaata gcgatgtggc tccccaaagt
    40561 ataggaagca ggtggaatga caatcttgaa aggcataaca attggaatca aaatcgcaat
    40621 agccgttaaa agggctgtca ttgtcataaa ttgtgtcttt ttccgtgtat tcacaagaat
    40681 ctccttttta actgcatata cactagtatg gtacaataaa ccagacaata aagcaagaat
    40741 ttacttgggt ttatagatca ttttttagtt aaaagttata gtagatggaa actagaatag
    40801 tccacctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgtcc
    40861 tgttcttatt tcgttttact atagtaaaga tttcattaaa aagaaactgt atagagcaaa
    40921 atctccacct tcaggtttga aagcggagat tgtttttatt ttttcaaggt ttgtagtcgt
    40981 ggaacaatgg ctagggttag aattgcagaa atgaccaatt cagcaattga atttgttgag
    41041 ataacggttg ccagaagaag ttggatattt ccattataaa catttccaaa taggaagaag
    41101 attcctccaa ggacaaagat agtatttgtc aaggaaccga gggctccagc taaaatcaga
    41161 ccagtcttgt ttttcatcag tttatagact aagtaaggag ttaaaccaat caaaatacgt
    41221 gggacgatgg caatgatagc tgagtagatg tttccgtttg gtacgaaggg agagaagagg
    41281 tagcttgtcg gtagaatcgt aatcgtgtta accgtcaagc taagtaatcc catcaaaaat
    41341 ccaagtgtaa ccccaactcg tggaccataa ataatgctgg caataatgac aggaatatga
    41401 acaatggtcg gtttgattgg aaatggaaaa aggttaaaga taagtgagct cagaaagtgt
    41461 atcacgagca tggtagcaaa aaagatagca atgggtgcaa tattagagcg ttttttcatc
    41521 gatagtttcc tttattcttt ctaaaataat tgtgaggtca gctaaagctc ctcgtccgtg
    41581 gtctccacaa gctagtaggg attccttagg agcaatcagc tgatagccgt aggtttctaa
    41641 tgttttcaga ttattctgag ttactggatg gtcatacatt tttgtattca tagcaggagc
    41701 tattagtttg ggaatatgac ttggtagggc tagagctgta ctggttacca tgttgtccgc
    41761 aaatccgtga gctagttttg caatagtgtt agcagttgca ggtaccacga taaataaatc
    41821 tgcttttttt ccaagttcga tatgattgac ctgatcagga tagggttcct tcatgacatc
    41881 caagtggaca ggattctgtg agagtacctg tagtgtcaaa ggttggataa actctgtagc
    41941 agcctgagtc attaagacag tgacttgatg gccttgtttt tttagagaac tgactaaatc
    42001 tgccgactta taagaggcga ttgaacccgt tacagccaag agaatgtttg ccatagtttt
    42061 cctttctaag aatgataggc ttgaattttt tcaaggagga gttctgcaat ttcttcttta
    42121 gtctggactg tttgaagctg atttttctca acaaatatag ctcggtgctg atctgctgaa
    42181 atttgagtca ggtcattcgc gatgattaaa tctgcttgat tcttgataag actttttcgt
    42241 gcaatgtcaa ccagatgatc ttcggtaaca tcaaccagca gtttgaaacc aatcagatga
    42301 atagtgggat tccattcctt gactagggat atgattttgg gtgtcttttt aaggaacaaa
    42361 acctgaacct catcagttga agaaatcttg gcctgatgat tctgcttgct taaaaattct
    42421 tttagattgg agctagcctg aacttcctca agccctgtca tataaacagg agtgtagtca
    42481 gaaacagcca ttgagtggat caagacctga taatcctgaa cacgttcttg catttctatt
    42541 agaaggttct tggtattggt aatttctcga atacttaggt taggatgagg ctctggcttc
    42601 agagctcgtt ttgtcgtaat taaacaaact tcatgccctg cagaaagcaa agtctctgtg
    42661 ataattttcc ccaagtgacc tgtagaatgg ttagtgatag agcggacgct atcgatagct
    42721 tcactggtac cgcccgatgt aactaaaatt ttcatagcac tattgtacac aaaaataagc
    42781 ggtaagtaaa atgaaagtga taaatttttg gtaaaaacga agatttacta tagtttcaaa
    42841 ctataaagcc atataaaatt taagaaagga ctctaaaatc cttaaaaaca gagatattta
    42901 cgaacgttta gagagtttta ggatgttaaa aatcttgttt tgtgatataa tgaattatca
    42961 tataagaggt tagaggaatt ttgaatgaaa acagatattg aaatcgcaca gagtattgag
    43021 ttgaagccaa ttgttgatgt tgtagagaaa cttggtattt cttatgacga tttggagttg
    43081 tacggaaagt acaaggctaa actcagcttt gataaaattc gtgcagttga gagcaatcca
    43141 gtcggtaaat tgatcttggt tactgccatc aacccaacac ctgcaggtga aggaaagtcg
    43201 acgcttacca ttggtcttgc ggatgccttg aacaagattg gcaagaaaac catgattgct
    43261 atccgcgaac cgtctcttgg tccagtcatg gggatcaagg gtggtgctgc tggtggtggg
    43321 tatgcacaag ttctgccaat ggaagacatc aacctccact ttactggaga tatgcatgct
    43381 attacaactg ccaacaatgc cctttctgcc ttgattgaca accacttgca ccaagggaat
    43441 gagctggaaa ttgatcaacg tcgtatcctc tggaaacgcg ttgtggactt gaacgaccgt
    43501 gcgctccgcc atgtgactgt tggtcttggt ggtcctctaa acggtattcc acgtgaggat
    43561 ggttttgata ttacagttgc ttcagaaatc atggcaattc tttgcttggc aacggacatc
    43621 gaggacttga aacgtcgttt ggcgaatatc gttattggtt atcgctatga ccgtacgcct
    43681 gtttctgtag gtgatttgca ggttgagggt gccttagctt tgattttgaa ggatgctatt
    43741 aagccaaact tggttcagac aatttacggt acacctgcct ttgtacacgg tggtccattt
    43801 gccaatatcg ctcatggctg taactctgtt ttggcgacga caacagccct tcacttggct
    43861 gattacactg ttactgaagc tggttttggt gcggaccttg gtgctgagaa attccttgat
    43921 atcaagacac caaacttgcc aacatctcca gatgcagttg tcattgtcgc aacccttcgt
    43981 gcccttaaga tgaatggtgg tgtggctaaa gacgctctga ctgaagaaaa tgtagaggca
    44041 gttcgtgcag gttttgctaa cttgaaacgc cacgttgaaa atatccgtaa gttcggtatt
    44101 ccagcagttg tagctattaa cgaatttgta tctgatacag aagctgaaat tgcagtctta
    44161 aaagaactct gtgcctcaat cgatgtacca gttgaattgg ctagtgtctg ggctgatgga
    44221 gcagaaggtg gagtagcact tgccgaaaca gttgttaaga caattgctga aaatccagct
    44281 aactataaac gtttgtacga taatgccctt tctgtccaag aaaagattga aaaaattgtc
    44341 actgaaatct atcgtggtag caaagtgaac tttgagaaga aagctcaaac acaaattgct
    44401 caaatcgttc aaaacggttg ggacaaattg ccaatctgta tggctaaaac tcaatacagt
    44461 ttctcagaca atccaaatgc gcttggagca ccagaaaact ttgaaattac cattcgtgaa
    44521 ttggtaccaa aattaggtgc aggcttcatc gttgccttaa ctggtgatgt tatgaccatg
    44581 ccaggtcttc caaaacgtcc agcagctctc aacatggatg ttgaaagcga tggaactgta
    44641 ctaggcttgt tctagtggat tgaaattgac tttaagtgag tttggaaata atatccaagc
    44701 tcattttttc tcagactgca agcagttcat caataagatt tatactcttc gaaaatctct
    44761 tcaaactacg tcagcttcac cttgccgtag gtatatgata ctgactctgt cagtt
//
LOCUS       DAVLCS010000013        42318 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLCS010000013 DAVLCS010000000
VERSION     DAVLCS010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42318
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.013"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(47..529)
                     /locus_tag="VXC78_000828"
     CDS             complement(47..529)
                     /locus_tag="VXC78_000828"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV0582940.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(624..2108)
                     /locus_tag="VXC78_000829"
     CDS             complement(624..2108)
                     /locus_tag="VXC78_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV0582941.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFLNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            2261..3871
                     /locus_tag="VXC78_000830"
     CDS             2261..3871
                     /locus_tag="VXC78_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV0582942.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGAKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKSVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVEMTD"
     gene            complement(4015..5412)
                     /locus_tag="VXC78_000831"
                     /pseudo
     CDS             complement(4015..5412)
                     /locus_tag="VXC78_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            5588..7033
                     /locus_tag="VXC78_000832"
     CDS             5588..7033
                     /locus_tag="VXC78_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0582943.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLMSVTAPTGTDNENIQKLLSDIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEHPDYASKIKKIYTKGFTKKVEAP
                     KTSKDQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVYNDQ
                     DFTSLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDHDRGRNQQKVIAAILQKLTSS
                     EALKNYSRIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGMGRTDLPSY
                     AMPDSNLYMMEINDSSLASVKTAIQDVLEGR"
     gene            7035..7766
                     /gene="cps4B"
                     /locus_tag="VXC78_000833"
     CDS             7035..7766
                     /gene="cps4B"
                     /locus_tag="VXC78_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEV0582944.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTSDVLDKLEKNRIPTLNNS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELINMGCYT
                     QVNSSHVLKSKLFGERYKFMKKRAQYFLERDLVHIIASDMHNVDSRPPHMAEAYDLVS
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            7775..8467
                     /locus_tag="VXC78_000834"
     CDS             7775..8467
                     /locus_tag="VXC78_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEV0582945.1"
                     /translation="MKEQNTIEIDVFQLLKTLWKHKLIILLVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQNVLEKVATNLKLD
                     IPAKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIIAVTRVSDVT
                     TLEEARPAMTPSSPNVRRNTLVGFLGGAAVTVITVLLIELLDTRVKRPEDVEDVLQMP
                     LLGVVPDFDKMK"
     gene            8477..9166
                     /locus_tag="VXC78_000835"
     CDS             8477..9166
                     /locus_tag="VXC78_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV0582946.1"
                     /translation="MPTLEISQAKLELVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     AGEGKTTTSTNIAWAFARAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIVVDTAPVGVVI
                     DAAIIMQKCDASILVTKAGETKRRDLQKAKEQLEQTGKSCLGVVLNKLDTSVEKYGSY
                     GSYGNYRKQKK"
     gene            9181..10542
                     /locus_tag="VXC78_000836"
     CDS             9181..10542
                     /locus_tag="VXC78_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0582947.1"
                     /translation="MSEKLAKPSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYIL
                     HYFVFYISDYGRNFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LLLHVFLVYVLNPFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESDDVVGEL
                     VAVSVLDKPDFQHDDLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDWARNKQICEMAGLNVVTFSTTFYKTSHVIAKRVIDIVGSLVGLILCG
                     LVSIVLVPLIRKDGGSAFFAQTRIGKNGRHFTFYKFRSMCVDAEEKKRELMEQNTMQG
                     GMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQK
                     RRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDGWTIWKDIEILLKTVKVVLMKD
                     GAK"
     gene            10548..11291
                     /locus_tag="VXC78_000837"
     CDS             10548..11291
                     /locus_tag="VXC78_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HEV0582948.1"
                     /translation="MNERIQILGITIDPLTMKETVDAVEQYVLKKHPLHLMGVNADKI
                     NQCYEDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMKHLLELSNEKG
                     YSVYFFGAKEDVLQDMLKIFEERYPALNVVGYRNGYFSPEDEKHIQEDIKEKKPDFVF
                     VGITSPKKEYIIQSFMDNGINAVFMGVGGSFDVLSGHIKRAPLWMQNAHLEWLFRVAN
                     EPKRLFKRYFVGNVSFIRKVLRAKRGYKL"
     gene            11288..12112
                     /locus_tag="VXC78_000838"
     CDS             11288..12112
                     /locus_tag="VXC78_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HEV0582949.1"
                     /translation="MNQTEIVKLIQKVELDAIKEFQKICKENNIDFFLRGGSVLGAVK
                     YDGFIPWDDDMDIAVPREGYDKLPGIFKDRIIAGKYQVLAYQYCDTLHCYFPRLFLLE
                     DERKRLGLPRNTNLGLHLIDIIPLDGAPNHSFLRKLYFGKVYWYRFLASLGTTYVGDH
                     VDMHSAKQKLIIGFFKKLGFAKLFPQNYVYRRLDNLYKKYGWKKQKYAGTINASLFAK
                     EVMPVEIWGEGVEKPFEDAFFKVPTEYDRYLKRLYGENYLHEEPSDDEKKSHLGGQ"
     gene            12114..12992
                     /locus_tag="VXC78_000839"
     CDS             12114..12992
                     /locus_tag="VXC78_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0582950.1"
                     /translation="MFCYIILHYKVLEETISCVKSIKEGNSNTKQIVIIDNFSNNGTG
                     EKLQELYESDSEIDVLINHENAGFARGNNVAYQFAKEKYKPDFMVIMNNDIEIETEEF
                     EKIVTDIYRKEKFHLLGPDIFSTTYQLHQNPKRLTHYTYEEVKALNEKFKKGSQVSLA
                     LKIKCWLKSSKVLRTAIYQNRRKKKSVDYRKQVENPILHGSFIVYSRDFIEKEEYAFN
                     PNTFFYYETEILDYEAELKGYKRIYTPKIKVLHHQNVATNQVYTNLVEKTLFSNKCNF
                     ESTSYFLKLMKENEGV"
     gene            12993..14327
                     /locus_tag="VXC78_000840"
     CDS             12993..14327
                     /locus_tag="VXC78_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEV0582951.1"
                     /translation="MTYLFLLCLTLFLLTFFYFFAFNQDLIAPPVVMSVMFLISSVFA
                     LINVQNWNIEYSGLAYLLIISGIIVFSMPLLALNSPILNTKIKVTDRLIDIQFWKIAL
                     TIIVDLIILYLYRREIHNLALSHGYTGSNFQWFFRNATSYEGELTVRTSIRVLIRIID
                     VSAYIFGYTFINNFFIYSHKRSKDLLLLVPFLIFISKTLLSGGRLDIIKILIAYVVMA
                     YIQQKRKVGWDKVISHKYMRLGFVGLIAGIPTFYYSLFLSGRSTTRTVFESISTYLGG
                     SIQHFNQYIQNPIGVAEVFGDESFVAIMNILGNLGFVNYNSTVHLEFRQLGITMGNVY
                     TFFRRPWHDFGLVGMYIFSFVVGVFFAIFYLKLRKSRAGFKLDIHTIIYSYFFYWIFL
                     SSIEQYSFTTISLFTLVFIVLVYLMAFFYWNLDFHRGKLVIKLSDTSIKSEN"
     gene            14355..15779
                     /locus_tag="VXC78_000841"
     CDS             14355..15779
                     /locus_tag="VXC78_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582952.1"
                     /translation="MNSKIKNILTNFSYVISSNLLTVLTSSLVVLIFPKLMGVTEYSY
                     WQLYIFYLTYIGFFHLGWIDGIYLKYGGLEYNNLDRKQFYSQMILFSSFLMIISLLLF
                     GLNVLAVTDSNARYIYNMTIISMIITNLRTLYVYVLQMTNRLKDSSIILLSDRVLYVL
                     LLFLFIVFGWHEYKVMILADILGRSFSLILSFWICKDIVFQPLSKFIFNIKESFDNIR
                     VGINLMLSNIASSLIIGIVRLGIQWNWNIETFGKVSLTLSVSNLLMTFINAIGLVVFP
                     LLRRTKAENLPKIYSNLRNVLMLIMFAILLIYYPLKIVLDLWLPAYQDALIFMTLIFP
                     MSVYEGKMALVINTYLKALRMERDILRVNALVMLISMGVTLVTTYLLNSLELTVVSIV
                     VLLALRSIIAELILSKKLDVSVKKDIVLEFLLTLVFISSSWYLPIGLAVIVYTIAYGL
                     YLYLKHEDIKTYLAYFKASKKTSN"
     gene            15844..16932
                     /gene="wecB"
                     /locus_tag="VXC78_000842"
     CDS             15844..16932
                     /gene="wecB"
                     /locus_tag="VXC78_000842"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HEV0582953.1"
                     /translation="MKKIMLVFGTRPEAIKMCPLVNELKKHEDMETIVCVTGQHKEMV
                     SPVLDLFGVVPDYDLEIMKANQTLFSITTSILEKIKPVLEKEQPDIVLVHGDTTTTYA
                     AALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIATYHFAPTELAKENLLKE
                     GRENVYVTGNTVIDALTTTVQEDYTHTHLDLNANNRLILLTAHRRENLGEPMRHMFRA
                     VKRVLNEYEDVKVIYPIHKNPLVRETAAEIFGDTERIQIIEPLDVLDFHNFMNQSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEETIYQNFKLLLDDSG
                     EYKKMSQASNPYGNGDASQQIVQILRGI"
     gene            17095..17964
                     /gene="rfbA"
                     /locus_tag="VXC78_000843"
     CDS             17095..17964
                     /gene="rfbA"
                     /locus_tag="VXC78_000843"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV0582954.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFLIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKQIKPSARGELEITDVNKAYLNRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEISYRMGYISREDVLELAQPLKKN
                     EYGQYLLRLIGEA"
     gene            17965..18558
                     /locus_tag="VXC78_000844"
     CDS             17965..18558
                     /locus_tag="VXC78_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV0582955.1"
                     /translation="MSDNFFGKTLVVRKIDAIPGLLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAAGKLQNNVSFSRKNVLRGLHAEPWDKYISVADDGKVLGSWVDLREG
                     ETFGNVYQTEIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPALGIEWENLAEAEVSEADKHHPLLRDVKPLTKDEL"
     gene            18570..19616
                     /gene="rfbB"
                     /locus_tag="VXC78_000845"
     CDS             18570..19616
                     /gene="rfbB"
                     /locus_tag="VXC78_000845"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV0582956.1"
                     /translation="MTEYKKIIVTGGAGFIGSNFVHYVYNNFPDVHVTVLDKLTYAGN
                     RANIEEILGDRVELVVGDIADAALVDKLAAEADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGLGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQPAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKETIKWYTDNQDWWKSEKE
                     AVEANYAKTQQVIK"
     gene            complement(19678..20532)
                     /gene="rfbD"
                     /locus_tag="VXC78_000846"
     CDS             complement(19678..20532)
                     /gene="rfbD"
                     /locus_tag="VXC78_000846"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV0582957.1"
                     /translation="MILITGANGQLGTELRYLLDERNVDYVAVDVTEMDITNSEMVEK
                     VFAEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTENVAKASEKYGAILVYISTD
                     YVFDGKKPVGQEWEVDDIPDPQTEYGRTKRMGEELVENLTSQHYIIRTAWVFGNYGKN
                     FVFTMQSLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYVTENQKEYGYYHLSNDAAEDT
                     TWYDFASEILKDSDVEVVPVDSSKFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALKE
                     FYKQEVRK"
     gene            20778..22760
                     /locus_tag="VXC78_000847"
     CDS             20778..22760
                     /locus_tag="VXC78_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0582958.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKAEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            23060..28363
                     /locus_tag="VXC78_000848"
     CDS             23060..28363
                     /locus_tag="VXC78_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0582959.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSQVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGSKTEEELLALEKEKPAE
                     EKPKEDKPAVAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGNYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMEALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSIVSDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTSLFLASVSLALSALFVVKTKKD"
     gene            complement(28530..30689)
                     /locus_tag="VXC78_000849"
     CDS             complement(28530..30689)
                     /locus_tag="VXC78_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HEV0582960.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(30686..31282)
                     /gene="recU"
                     /locus_tag="VXC78_000850"
     CDS             complement(30686..31282)
                     /gene="recU"
                     /locus_tag="VXC78_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV0582961.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            31348..31875
                     /locus_tag="VXC78_000851"
     CDS             31348..31875
                     /locus_tag="VXC78_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV0582962.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFENHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            31945..32274
                     /gene="gpsB"
                     /locus_tag="VXC78_000852"
     CDS             31945..32274
                     /gene="gpsB"
                     /locus_tag="VXC78_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV0582963.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            32295..32675
                     /gene="rnpB"
                     /locus_tag="VXC78_000853"
     ncRNA           32295..32675
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VXC78_000853"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            32760..33917
                     /locus_tag="VXC78_000854"
     CDS             32760..33917
                     /locus_tag="VXC78_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV0582964.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDARVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            33930..35324
                     /gene="mapZ"
                     /locus_tag="VXC78_000855"
     CDS             33930..35324
                     /gene="mapZ"
                     /locus_tag="VXC78_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV0582965.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLEDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPQPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            35400..36824
                     /gene="gndA"
                     /locus_tag="VXC78_000856"
     CDS             35400..36824
                     /gene="gndA"
                     /locus_tag="VXC78_000856"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV0582966.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELVNSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            36836..37525
                     /locus_tag="VXC78_000857"
     CDS             36836..37525
                     /locus_tag="VXC78_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0582967.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            37623..38651
                     /gene="cbpC"
                     /locus_tag="VXC78_000858"
     CDS             37623..38651
                     /gene="cbpC"
                     /locus_tag="VXC78_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV0582968.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQE
                     KWYYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWI
                     YEEGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGK
                     MLTDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRS
                     SGAMATGWYQDGSTWYYLDPSNGDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYN
                     FASSGEWI"
     gene            38669..39667
                     /gene="cbpJ"
                     /locus_tag="VXC78_000859"
     CDS             38669..39667
                     /gene="cbpJ"
                     /locus_tag="VXC78_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEV0582969.1"
                     /translation="MKILKKMMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWRTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYIGGERRAGWINDASAWYYLDPATGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(39785..41017)
                     /locus_tag="VXC78_000860"
     CDS             complement(39785..41017)
                     /locus_tag="VXC78_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0582970.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(41028..41648)
                     /locus_tag="VXC78_000861"
     CDS             complement(41028..41648)
                     /locus_tag="VXC78_000861"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582971.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKVDLFDFGIGSMGVYWCLLNNKFPFDVQT"
     gene            complement(41548..41886)
                     /locus_tag="VXC78_000862"
     CDS             complement(41548..41886)
                     /locus_tag="VXC78_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
                     /protein_id="HEV0582972.1"
                     /translation="MTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANV
                     TAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLKTFIHNSIWGNLSLFPTK
                     RYSQRKHFRL"
BASE COUNT        12888 a         7462 c         9322 g        12646 t
ORIGIN      
        1 acgtacggtg gtgtgagagg ggctagagat tatcccctac tcgattttaa atcacatgac
       61 gttcaaaggc atcatctgaa atcccttgtt ccaagatgag ttttgcccat tctttagcag
      121 agaagaggct gtggtccttg tagtttccgc aagattcgat ggttgtccct gggacatctt
      181 cccaagtagt agtttcagcg atttccttga gcgaatcctt gataacagct gcgattttag
      241 cactggtgtg acgtccccac ataatcatgt ggaagcctgt gcggcaacca aatggtgaac
      301 agtcaatcat gccgtcaatg cgggtacgga tgagtttggc taagaggtgc tcgatagtgt
      361 gaaggccggc agtagggata gagtcttcgt ttggttgcac caagcgaata tcataattgg
      421 agatgatgtc tccttttggt cctgtttctt ccccaatcaa gcgaacatag ggtgctttga
      481 caatggtgtg gtcaagttca aaactttcga caataacttc ttttgacatg gtaaatcctt
      541 tcagttttct tctctcatta tatcataaag gttgctcctg agacagagag aaaacctctc
      601 cgaggctgga gaggttgaaa tctttactta cgatataagc ggtcgtattg gtagtatggg
      661 tcaaaggtta cgttgatacc cagtttacga aggacattct tgtcttcatc agtcaagatg
      721 atggttgagt gggcttcgct tcctttgagg ttgccgagtt cttccatagc gcgggcagca
      781 tcaggatttt ctgtagctgt gatagcaagt gcaatcagga tttcatttga atgaaggcgt
      841 ggattgcggc taccgagatg atcgatttta agaccttgga ttggcttaac aacttccggc
      901 tcgattaatt ttacttcttt agcgatgtca gctgattttt tgatggcgtt gatcaaggca
      961 gcggctgtag ggccaaagag ttctgagttc ttaccagtga cgatttcccc atttggcaat
     1021 tcaaaggcta gggctggtcc accagtttct tctgcttttt ggcgcgcaac gacagcaacc
     1081 ttacggtctg caggtgtgat accgaggtcg ttcatgagca actcaatttt cttgacggca
     1141 gcttcgccaa ctttttcagc tttgaagtca agaactgttt gatagtaacg gcggatgatt
     1201 tcttgtttag aagcttcgac agcagcctcg tcatctgtaa tagcgaaacc aaccatgttg
     1261 acacccatat ctgtcggtga agcgtatggt gattttccga gaatacgttc caacatgcgc
     1321 ttgagcactg ggaagatttc gatatcacgg ttgtagttga cagtggtttc tccataggtt
     1381 tgaagatgga aggggtcaat catgttgaca tcatcaaggt cagctgtggc agcttcataa
     1441 gccaagttaa ctggatgatg aaggggaaga ttccaaacag ggaaggtttc aaatttagcg
     1501 tagccagact tgatgccatt gatttggtcg tggtacatat tggacataca cgttgccaat
     1561 tttccagaac cgggtccagg agcggttacg acaatcaagt tgcgactggt tttgatgtag
     1621 tcgtttttgc ccatgccttc tggggaaatg atgtgatcca tatccgtcgg atatcctttg
     1681 attggataat gaagataaga atcaattccg tttttctcaa gttggttgag gaaggcatct
     1741 gcagcgggtt ggccagcgta ttgtgtaatg acaacggaac caacaaaaat ccctaattca
     1801 ttgaatttgt caatcaaacg aagaacttct tggtcataag aaatgcccaa gtcgccacgt
     1861 gctttggaat gttcaatgtt gctagcatta atggcaatca caacctcaac ctgctctttc
     1921 aattcttgca agagcttgat tttgttgtca ggttcataac caggaaggac acgagcagcg
     1981 tggaaatctt ctaacatttt accgccaaac tctaagtaga gcttgccgtc aaattggtta
     2041 atgcgttcca aaatatggtc gcgttgtaaa ttcaaatatt gttcagaact aaaagcttgt
     2101 tttttcattt ttttacctct gacctctatt ataataaaaa attggaagtt aggaaactac
     2161 ggagctaaaa aagaaattaa aaagattaag caaacgcttg cacaaaattt taaaaagtgt
     2221 tatcatatac tatagattat gaaaataatg aggtaaacag atgcaagaaa aatggtggca
     2281 taatgccgta gtctatcaag tctatccaaa gagttttatg gatagtaatg gagatggagt
     2341 tggtgatttg ccaggtatta ccagtaagtt ggactatcta gctaagttag gaatcacagc
     2401 gatttggctt tctcccgttt atgacagccc tatggatgat aatggctacg atattgctga
     2461 ttatcaagcg attgcaacga tttttggaac catggaggat atggatcaac tgattgcgga
     2521 agctaagaag cgtgacattc gtatcatcat ggacttggtg gttaatcata cctcagatga
     2581 acatgcttgg tttgtcgaag cctgtgaaaa tactgatagc cctgagcgag actactatat
     2641 ctggcgcgat gaacccaatg acctagattc tatctttagt gggtctgctt gggaatacga
     2701 tgaaaagtca ggtcaatact atctccactt tttcagcaag aaacagccgg atctcaactg
     2761 ggaaaatgaa aaacttcgcc agaaaattta tgagatgatg aacttctgga ttgataaagg
     2821 tattggtggt ttccgtatgg atgttattga catgattggc aaaattcctg acgagaaggt
     2881 agtcaataat ggtcctatgc tccatcccta tctcaaggaa atgaatcagg cgacctttgg
     2941 agctaaggat ctcttgacag taggggagac ttggggagca acgccagaga ttgccaagct
     3001 ctactctgat ccaaaggggc aagaattgtc tatggtcttc cagtttgaac atatcggtct
     3061 tcagtatcag gaaggtcaac ctaaatggca ctatcaaaaa gagctgaata tcgctaagtt
     3121 aaaagaaatc ttcaacaaat ggcagacaga gttaggagtt gaggacggct ggaattccct
     3181 cttctggaac aaccatgacc tccctcgtat tgtctcaatc tggggaaatg accaagaata
     3241 ccgcgaaaaa tctgccaaag cctttgcaat cttacttcat ctcatgagag gaactcctta
     3301 tatctaccaa ggtgaggaga ttgggatgac caactatccg tttgaaacac tggatcaagt
     3361 agaagatatt gaatccctca actatgcgcg tgaggctctt gaaaaaagtg ttccgattga
     3421 agaaatcatg gacagtatcc gtgttattgg acgtgacaat gcccgtaccc ctatgcaatg
     3481 ggacgagagc aaaaacgctg gtttctcaac aggtcaacct tggttggcgg ttaatccaaa
     3541 ttacgagatg atcaatgtcc aagaagcgct ggcaaatcca gattctattt tctataccta
     3601 tcagaaactg gtccaaattc gcaaggagaa tagctggcta attcgagctg actttgaatt
     3661 gcttgatacg gctgataagg tctttgctta tatacgtaag gatggcgacc gtcgcttcct
     3721 agttgtggct aacttgtcca atgaagagca agacttgaca gtagaaggaa aagtcaaatc
     3781 tgtcttgatt gaaaacaccc tagctcaaga agtctttgaa aaacaaatct tagttccatg
     3841 ggatgctttc tgtgtggaaa tgactgacta gaatgagcaa acctcaagtt tttgaagctt
     3901 gaggtttttt actatagtgg attgaaacta gaatagtgca cctctgcttc taaaacattg
     3961 ttagaaatcg atttgactgt cctgatcgat ttgtcctatt cttatttcat tttgctatac
     4021 ttgtagttga ggagaattaa gctcctcact agtaaactct tcataatcct ttttattttt
     4081 atgaagatat tgtttgaaag atgtgagttt ccacggatgg gtttgtggag ggatatactt
     4141 gcgtctttct ttttttgttc tggttcttgt tcaaagtttt tcgaatagag ttcatgattt
     4201 agtagctcct ttgtgtgata gattttgtca gcgatattga ggtagatgtc tccgtcaaat
     4261 gcttttataa ctaatgcttt cgtctttctg atgaaataga cttcttttcc ttgttcggta
     4321 gggatatagt aacgattttg gaatcggata tggtgtccac tatcgacgac tctctccgcc
     4381 agtctagcca gaatgagatt cctttcagag gggttaggaa cctcctcgaa gacagagagt
     4441 tttgtcttgt ttccaaactg ttcattaaag gtttgaatgt aggaaagcag gaaggtattg
     4501 gcttcttcca aggtatgaat attgttttgt tccagttcga taggcaggcg agattgtagt
     4561 gtctgattga gtctttcgac tctcccttta gcttgaggga tagaggttgt ctcaaggaga
     4621 atccctagtt ggtgacaggc gtatccaaac tgtgtatggg tatcgtcctc cattttctta
     4681 gagttggagg cttgataggt aaagaccgtt ctcttatctg ttttaatttg aaggggaatg
     4741 ccgtgattgg ctaagatttg ttcgaggaca tgatagtaag cattcaagtt ctcttgttta
     4801 tcaaaataag cgcctaggat attgccagaa gcatcatcaa tggctaagtg taagttagat
     4861 gtttgggctc caaactaggc atgaggactg gcatccattt gaatgagttc accagcaaat
     4921 ttctttctgg gtctactagg atgtactttt ttagggtctt caaggaagtt ttcagccgtc
     4981 ggtaagattg gattgtctag gggttgattc aggttcagtt tagcttgttt tcttactctc
     5041 ttctttgtct ttctatggga cttaggcgac aggatatttt tcttatagag tatttttcta
     5101 acagtagtat cagagagctg aattccttct tcttcagcta gcaattcaca gaaatgaagg
     5161 acatttggtt tatatgtttc ataggagagg tattttttta ggagacgttc tttgatttca
     5221 tcagggattg catgttttgg ttttcgattt ctgtttccgt gtctgaaggc ttctttgtcc
     5281 tttcagttga taggctagta gcagacgatt gatttgtctt tcagaaagat tgagctcgac
     5341 acaggctcgt ttctttgttt tctttccttg ggctatagct tttatcacaa gatatttttt
     5401 cgtttcattc atattcagtt ggatcctttt catatgacta ttctaccaaa tgggacattt
     5461 tcacgttcga tttactaaag acattatcac attcgaatta cacaagatgc agatagtaaa
     5521 aaaaaatgta gacattaccg taaaaaagtg atataatcgt atgatgttca aggtataggt
     5581 gttaatcatg agtagacgtt ttaaaaaatc acgttcacag aaagtgaagc gaagtgttaa
     5641 tatcgttttg ctgactattt atttattgtt agtttgtttt ttattgttct taatctttaa
     5701 gtacaatatc cttgctttta gatatcttaa cctagtggta actgcgttag tcctactagt
     5761 tgccttggta gggctactct tgattatcta taaaaaagct gaaaagttta ctatttttct
     5821 gttggtgttc tctatccttg tcagctctgt gtcgctcttt gcagtacagc agtttgtggg
     5881 actgaccaat cgtttaaatg cgacttctaa ttactcagaa tattcgatca gtgttgctgt
     5941 tttagcagat agtgagattg agaatgttac gcaactgatg agtgtgacag caccgactgg
     6001 gactgataat gaaaacattc aaaaactact atctgatatc aaatcaagtc agaataccga
     6061 tttgacggtc aatcagagtt cgtcttactt ggcagcttat aagagtttga ttgcaggaga
     6121 gactaaggcc attgtcttaa atagtgtctt tgaaaatatc atcgaatcgg agcatccaga
     6181 ttacgcatcg aagataaaaa agatttatac caagggattc actaaaaaag tagaagctcc
     6241 taagacgtct aaggatcagt ctttcaatat ctatgttagt ggaattgata cttatggtcc
     6301 gattagttcg gtgtcgcgtt cagatgtcaa tatcctgatg actgtcaatc gagataccaa
     6361 gaaaattctc ttgaccacaa cgccacgtga tgcttatgta ccaatcgcag atggtgggaa
     6421 taatcaaaaa gataaattga cccatgcggg catctatgga gttgattcgt ccatccacac
     6481 tttagaaaat ctctatggag tggatatcaa ttactatgtg cgattgaact tcacttcttt
     6541 cttgaaattg atcgatttgt tgggtggggt agatgtttat aatgaccaag attttacatc
     6601 tctacacggg aagttccatt tcccagttgg aaatgtccac ttagattctg agcaggctct
     6661 gggatttgtt cgtgagcgct attccctagc ggatggtgat catgaccgcg ggcgcaatca
     6721 acaaaaggtg attgcggcca tccttcaaaa attaacttcg agcgaagcgc tgaaaaatta
     6781 tagtaggatc attgatagct tgcaagattc tatccaaaca aacatgccac ttgagaccat
     6841 gataaacttg gtcaatgctc agttagaaag tggtggaacg tacaaagtga attcgcaaga
     6901 cttgaagggt atgggacgga cggatcttcc ttcctatgcg atgccagata gtaacctcta
     6961 tatgatggaa attaacgaca gtagccttgc atctgtcaaa actgctattc aggatgtgtt
     7021 ggagggcaga tgaaatgatt gatattcatt cgcacatcgt ctttgatgta gatgatggtc
     7081 ccaagtcaag agaggaaagc aaggctctct tggcagaatc ctacaggcag ggggtgcgaa
     7141 ccattgtctc tacctctcac cgtcgcaagg gcatgtttga aactccggaa gagaagatag
     7201 cagaaaactt tcttcaggtt cgggaaatag ctaaggaagt ggcgagtgac ttggtcattg
     7261 cttacggggc tgaaatttac tacacatcag atgttttgga taagctggaa aaaaatcgga
     7321 ttccgaccct caataatagt cgttatgcct tgatagagtt tagtatgaac accccttatc
     7381 gcgatattca tagtgccttg agtaaaatat tgatgttggg aattactcca gtcattgccc
     7441 acattgagcg ctatgatgca cttgaaaata atgaaaaacg cgttcgagag ctgatcaata
     7501 tgggctgtta cacgcaagta aatagttcac atgtcctcaa atccaaactt tttggagaac
     7561 gttataaatt catgaaaaaa agagctcagt attttttgga gcgtgacttg gttcatatca
     7621 ttgcaagtga tatgcataat gtggacagca gacctcccca tatggcagaa gcatatgacc
     7681 ttgtttccca aaaatacgga gaagcgaagg ctcaggaact ttttatagat aatcctcgaa
     7741 aaattgtaat ggatcaacta atttaggaga aatgatgaaa gaacaaaaca cgatagaaat
     7801 cgatgtattt caattactta aaaccttgtg gaaacacaag ctaataattt tattagtggc
     7861 acttgtgaca ggggcgggag cttttgcata tagcactttt attgttaagc cagaatatac
     7921 aagcaccacg cgtatttacg tagtcaaccg taatcaagga gataagccgg gactgacgaa
     7981 tcaggacttg caggcaggaa cttatctggt aaaagactac cgcgaaatta tcctttcgca
     8041 aaatgtattg gaaaaggtag cgacaaattt gaaattggat attccagcaa aaacgttaac
     8101 tagcaaagtg caagtgactg taccagccga cactcgtatc gtctcaatct ctgtcaagga
     8161 taaacaacca gaggaagcca gtcgcattgc taattctcta cgagaagttg ctgcagaaaa
     8221 gatcatcgct gtaacgcgag tatctgatgt aacgacgctt gaagaagcgc gaccggctat
     8281 gactccctct tctccaaatg ttcgacgcaa caccttagtt ggttttcttg gaggagccgc
     8341 cgtaacagta attactgttc ttttgattga gttgctcgat acccgtgtaa aacgtcctga
     8401 agatgttgaa gatgtactgc aaatgccact tctaggagtc gttccagatt ttgataaaat
     8461 gaaataggag gaagttatgc caacgttaga aatctcacag gcgaaattag aacttgtgaa
     8521 aaaggcagag gaatattata atgctttgtg cacgaaccta cagttaagtg gagatgattt
     8581 gaaagtattt tctatcactt ctgtgaaagc aggagaagga aaaacaacga cttccaccaa
     8641 tatcgcttgg gcttttgcgc gtgcaggtta caaaacgctt ctgattgatg cagacatgcg
     8701 taactccgtt atgtcaggtg tctttaaatc aagggaaagg attactggac taacagaatt
     8761 tctatcaggg acaacagacc tgtcacaggg gctttgcgat accaatattg agaatctctt
     8821 tgtgattcag gctggctctg tgtcaccaaa tccgacagcc cttcttcaaa gtaagaattt
     8881 cagtacaatg cttgaaacct tgcgtaaata ttttgactat atcgtcgtag acactgcccc
     8941 tgtcggtgtc gtgattgatg cggctatcat tatgcagaaa tgtgatgctt ctattttagt
     9001 gacgaaggca ggtgaaacaa aacgacggga tcttcaaaaa gcgaaagaac agttggaaca
     9061 aactgggaag tcgtgtttag gagttgtgtt gaataaactc gatacttcag tagagaaata
     9121 cggttcttat gggagttatg ggaattacag gaaacagaaa aaataggttg agggatagaa
     9181 atgagtgaaa aactagcaaa gccttcagta gccatagtcc agagttttct tgttatttta
     9241 ttgacttatc tacttagcgc tgtgagagaa acagagattg tttcaacaac agctattgta
     9301 ctttatatcc tccactattt tgtcttttat atcagtgatt atggacggaa tttctttaaa
     9361 aggggatatt tgattgaact tgtccagaca ttgaaatata tcctattctt tgcgctagcg
     9421 attagtattt ctaatttttt cttagaagat cgatttagta tttccagaag aggcatgatt
     9481 tacttcctct tattacatgt tttcttagtc tatgtgctaa acccatttat caagtggtat
     9541 tggaagcggg cttatcccaa ctttaaagga agtaagaaga ttctcctact tacagcaact
     9601 tctcgtgttg aaaaggtact ggatagacta atagaatcag atgatgttgt tggggagttg
     9661 gtagccgtca gtgttttaga taaaccagat tttcagcatg atgatttaaa ggttgtagca
     9721 gagggggaga tagtaaattt tgcgactcat gaggtggtcg atgaagtctt tatcaatctt
     9781 ccaagtgaaa aatacaatat tggagagctt gtctctcagt ttgaaacgat gggaattgat
     9841 gtaacagtca atctaaatgc tttcgattgg gcacgtaaca agcaaatttg tgagatggca
     9901 ggactaaatg ttgtgacttt ttctacaaca ttttataaga ctagccatgt gattgctaag
     9961 cgggttattg atattgtcgg ttccctggta ggtttgatat tatgtggtct agtcagtatt
    10021 gtgctggttc ctttgattcg aaaggatggg ggttctgctt tttttgctca gacgcgtata
    10081 ggaaaaaatg gccgccattt tactttttat aagtttcgct ctatgtgtgt ggatgctgag
    10141 gagaaaaaaa gagaactcat ggaacaaaat accatgcagg gtggaatgtt taaggtggac
    10201 gatgatcctc gtatcacgaa aattggtcat tttatacgga agacgagctt ggacgagcta
    10261 ccacagtttt ataatgttct aaagggagat atgagtttgg taggtacacg accaccaaca
    10321 gtggacgagt atgagcacta taccccagaa caaaaacgtc gcctaagttt taaacctggc
    10381 ataacaggtt tatggcaggt cagcggacga agtgaaatca aaaatttcga tgaagttgtc
    10441 aaattagatg tggcctatat tgatggttgg acaatctgga aagatattga aattttattg
    10501 aagacagtta aggttgtatt gatgaaggat ggagcgaaat agttcatatg aatgagagaa
    10561 ttcaaatatt aggaattact atagatccat taacgatgaa agaaacagtg gatgctgttg
    10621 aacagtatgt tttaaagaag caccctttgc acttgatggg agttaacgcg gataaaatta
    10681 atcagtgcta tgaagatgag aaaatcaaaa aaatcgttaa tgaatcagga ataattaatg
    10741 ccgacggtgc ttcagtagtt ttagcgagta agtttttagg aacaccagtt cctgagcgag
    10801 ttgctggaat agacttgatg aaacatttac tagagttgtc taatgaaaaa ggatactcgg
    10861 tctacttttt tggagcaaaa gaagacgttt tacaagatat gttaaaaatt tttgaagaaa
    10921 gatatccagc tctaaatgtt gttggctata gaaatggata tttttcgcct gaagatgaaa
    10981 aacatattca ggaagatatt aaagagaaaa aaccagattt tgtgtttgta ggaattactt
    11041 ctcctaagaa agaatatatt atccaatcat tcatggataa tggaattaat gctgtgttta
    11101 tgggggttgg tggaagtttt gatgtactat cagggcatat caaacgagct ccattatgga
    11161 tgcaaaatgc tcacctagag tggttgtttc gtgtggcaaa tgagcctaaa cgtctcttta
    11221 agcgttattt tgtagggaat gtttcattta taagaaaagt tttaagagcg aaaaggggat
    11281 ataaactttg aaccaaacag aaatagttaa attgattcag aaagttgaat tggatgctat
    11341 aaaagagttt caaaaaattt gtaaagagaa caatatagat ttcttccttc gtggggggag
    11401 tgtacttggg gcagtcaaat atgatggctt tattccatgg gatgatgaca tggatattgc
    11461 tgtgcctcgt gaaggctacg ataaacttcc aggtatcttt aaggatagaa ttatcgcagg
    11521 caaatatcag gttcttgctt atcaatattg cgatacttta cattgctact ttcctcgctt
    11581 attcctttta gaagatgaaa gaaaacgttt gggattgcca cgaaatacca atttaggttt
    11641 gcatttgatt gatatcattc ctttggatgg tgccccaaat cattcatttt taagaaagct
    11701 ttacttcggt aaagtatact ggtatcgttt tttagcaagt ttaggaacta cctatgttgg
    11761 agaccatgtg gatatgcatt ccgctaagca aaaactaatc attggtttct ttaaaaagct
    11821 aggatttgca aaactattcc ctcaaaatta tgtgtacaga cgcttggata atctctataa
    11881 aaagtatggt tggaaaaagc agaagtatgc tgggacaatt aatgcatctc tgtttgccaa
    11941 agaagtcatg ccagtagaga tttggggaga aggagtagag aagccttttg aggatgcctt
    12001 ctttaaagtt cccacggagt atgaccgcta tctgaaaaga ctttacggag aaaactatct
    12061 tcacgaagag cctagtgatg atgaaaagaa atcgcattta ggaggacaat aatttgtttt
    12121 gttatattat tttgcattac aaagtcttag aggaaactat ttcttgtgtt aaatcaataa
    12181 aagaaggcaa ttccaataca aagcagatcg ttattattga taatttttct aataacggta
    12241 cgggtgaaaa actacaagag ctgtatgagt cagattcaga gattgatgtc ttgattaacc
    12301 atgaaaatgc tggtttcgct cgaggtaata atgtagcata tcagtttgct aaggaaaagt
    12361 acaaacctga ttttatggtt atcatgaata atgatattga gatagaaaca gaagagtttg
    12421 aaaaaatcgt gacagatatc tatcggaagg aaaaattcca tttgttagga ccagatatct
    12481 tttcgacgac gtatcagctt caccaaaacc caaaacggtt gacgcattat acttatgaag
    12541 aggttaaggc tctcaatgaa aaatttaaga aagggagcca agttagtcta gcattaaaaa
    12601 ttaaatgttg gttgaagtct agtaaagttc ttcggacagc aatctatcaa aataggcgta
    12661 aaaagaaatc agtagactat agaaaacagg tagaaaaccc aattcttcat ggttcgttta
    12721 ttgtatattc tagagatttt attgagaaag aggagtatgc ttttaatccc aataccttct
    12781 tctattatga aacagagata ttagattatg aagctgagtt aaaaggatat aagagaattt
    12841 atacaccgaa gattaaggtc ttgcaccatc aaaatgttgc aaccaatcaa gtctatacaa
    12901 acttagtaga aaaaaccttg ttttcaaaca aatgcaactt tgaatccact agttattttt
    12961 tgaagttgat gaaagaaaac gagggtgtgt aaatgactta tttattttta ctctgcctga
    13021 ccttattctt attaactttc ttctattttt ttgctttcaa tcaagatttg atagctccgc
    13081 cagttgtcat gtctgttatg tttctcatta gttctgtatt tgcccttatt aatgtgcaaa
    13141 actggaatat tgagtatagt ggtttagctt atcttttgat tattagtggc attattgttt
    13201 tttcaatgcc tctcttggct cttaattcgc ctattctaaa taccaagatt aaagtgacgg
    13261 atcggctcat tgatatccaa ttctggaaaa tagctcttac tattatagtt gacctcatta
    13321 ttctatatct ttataggaga gagattcata atcttgcact tagccatggt tatacgggtt
    13381 caaattttca gtggttcttt agaaatgcta ccagttatga aggtgagcta acagtgcgaa
    13441 cttcgattcg ggtcctcatt cgtatcattg acgtatctgc ttatattttt ggatatactt
    13501 ttattaataa tttcttcatt tatagtcata aacgctctaa agatttactg ctcttagttc
    13561 cattcttgat ttttatttct aaaaccttat tatctggggg tagattggat attataaaaa
    13621 ttttaattgc gtatgttgta atggcctata ttcagcaaaa acgaaaagtt ggctgggata
    13681 aggtcatctc ccataaatat atgagacttg gttttgtagg cttgatagct gggattccta
    13741 ccttttacta ttctttattc ttatctggac gttctacgac tagaactgta tttgaaagta
    13801 tttcaaccta tttaggaggt tcgattcagc attttaatca gtatattcaa aatcctattg
    13861 gagtagctga ggtttttggc gatgagtcat ttgtagctat tatgaatatt ttgggtaatc
    13921 ttggctttgt caattacaat agtaccgttc acttagaatt tcggcagtta gggattacta
    13981 tgggtaacgt ttatactttc tttagaagac cctggcatga ctttgggtta gtcggtatgt
    14041 atatcttttc ctttgttgtc ggtgtgtttt ttgctatttt ttatttgaaa ttaagaaaga
    14101 gccgtgctgg ttttaaattg gatattcata caattattta ctcttatttc ttttattgga
    14161 tttttttatc gtccattgag caatactcgt ttacaacaat cagtttgttt acacttgtat
    14221 ttatagtctt ggtttaccta atggctttct tctattggaa tttggatttc cacagaggaa
    14281 aactagtaat taaactctct gacacaagta ttaaatcgga aaactgaaaa caataaaaat
    14341 agagaggata gttgatgaat agcaaaatta aaaatatact aactaatttc tcttatgtca
    14401 tttcttcaaa tcttttgaca gtcttgacct cttccttggt tgtcttaatt ttccccaaat
    14461 taatgggggt aacagagtac agttactggc aactttatat tttttatctg acctatatcg
    14521 gttttttcca cttgggttgg attgatggga tttatcttaa atatggtggc ttagaatata
    14581 ataatttaga tagaaaacag ttttattctc agatgattct attttctagc ttcttaatga
    14641 ttatctcctt gctattgttt ggtttaaatg tattagctgt aacagattcg aatgcacgat
    14701 atatttataa tatgactatt ataagtatga taatcacaaa tttaagaacg ctctacgtgt
    14761 atgttttgca gatgacaaac cgcttgaagg atagttccat cattctactc agtgatcgcg
    14821 ttttatatgt gctcctttta ttcctgttta ttgtatttgg ttggcatgaa tacaaggtta
    14881 tgattttggc agatattcta ggtcgatcat tttctctcat actttccttc tggatttgta
    14941 aagatattgt gtttcagcct ttgtcaaaat tcatctttaa tataaaagag tcttttgata
    15001 atatccgagt tggtatcaat ttaatgttat ccaacatcgc aagtagtttg attatcggta
    15061 ttgttcgtct aggaatccaa tggaactgga atatcgaaac attcgggaaa gtatctctga
    15121 ccttgagtgt ttccaatcta ttgatgactt tcattaatgc cattggacta gtcgtctttc
    15181 cgctattaag acgaacaaaa gcagaaaact tacctaagat ttattctaat ttaagaaacg
    15241 ttttgatgct tatcatgttc gcgattttgc tcatttacta tcctttaaaa attgtattag
    15301 acctctggtt gccagcctat caagatgcct tgattttcat gacccttatt ttccctatgt
    15361 cagtctatga agggaaaatg gcattggtca ttaatactta cttaaaggca ttaagaatgg
    15421 aaagagatat ccttagagtc aatgccttag taatgttgat cagtatggga gtgaccctgg
    15481 ttacaacata cctgttaaat agtttggagc tgactgttgt atcgatagtt gttttgctag
    15541 ctttgagaag tatcatagcc gaattaattc tgtctaaaaa actggatgtt tcggttaaga
    15601 aggatattgt attagaattt cttttgacgc ttgtctttat ttcttcaagt tggtatttgc
    15661 cgattgggct ggcagtaatt gtctacacaa tagcctacgg tttatatctc tatttgaaac
    15721 acgaagatat caaaacctat ttagcttact ttaaagctag taaaaaaaca tcaaattaaa
    15781 aaattatata atgattaagt ggtagattct atttctaccg ttttagatat tcgggaggta
    15841 atgatgaaaa aaattatgtt agtattcggt acacgtccgg aagccatcaa aatgtgtcca
    15901 ttagtcaatg agttgaaaaa acacgaagat atggaaacaa ttgtgtgtgt tactggacaa
    15961 cacaaagaga tggttagtcc tgttttagat ttatttggtg ttgtaccaga ttatgattta
    16021 gaaattatga aggctaacca aaccttgttc tctatcacaa ctagtatctt ggaaaagata
    16081 aaaccagttt tagagaagga acaaccagat attgtcctag ttcacggtga cactacgaca
    16141 acttatgcag cagccttggc agcattctat ttgggaatta aagtaggaca tgttgaagct
    16201 ggtttgcgaa cgtacaattt acaaagtcca tttcctgaag aatttaacag gcaatcgaca
    16261 tcaatcattg caacttacca ttttgctcca actgagttgg ctaaagaaaa tctcttaaaa
    16321 gaaggtagag agaatgttta tgtgactgga aatactgtca ttgatgctct tacaactact
    16381 gttcaagagg attatacaca cactcattta gatttaaacg ctaacaatcg tctcatctta
    16441 ttgactgctc atagacgcga aaatctcggc gaaccgatga gacatatgtt tagagcagtt
    16501 aaacgagtat tgaatgaata cgaagatgtt aaagtcattt atccaattca taagaatcct
    16561 ttggtacgtg aaacagctgc agagatcttt ggagatacag aacggattca aattattgaa
    16621 cctttggatg ttcttgattt ccacaacttc atgaaccaaa gttatatgat tttaacagat
    16681 tctggcggag ttcaggaaga agcaccttct ttaggaaaac ctgtattggt tatgcgcgat
    16741 actactgaaa gacctgaagg agtagcggca ggaaccttga aattagtagg aactgacgaa
    16801 gaaacaattt atcaaaactt caaactactt ctagatgatt ctggagaata caaaaaaatg
    16861 agtcaggcta gcaatccata cggtaatggt gatgctagtc aacagattgt tcagattttg
    16921 cgtgggattt aagaagattc tctaaaagag tctaagagga atccactcca caaacataaa
    16981 actcttatgc tatcatttat gattgagata gactcataac ttaatatttt tatcctaaga
    17041 aaattcgttc atattcaata tgaatgaaaa acaacgaaga aaggttattt cattatgaaa
    17101 ggtattattc ttgcaggcgg ctcaggtacc cgcctgtacc cacttactcg ggctgcgtca
    17161 aaacagctga tgccggttta tgataaacct atgatttatt atccgttgtc gacattaatg
    17221 ttggctggaa ttaaagatat tttgattatc tcaactcctc aagatttgcc ccgttttaag
    17281 gacttgctct tggatggttc cgaatttggg atcaagcttt cctatgcgga acaacctagt
    17341 cccgatggac ttgctcaggc ttttcttatc ggtgaagaat ttatcggtga cgatagcgtt
    17401 gccttgattt taggcgacaa tatctaccat ggtcctggtc tgagcacaat gcttcaaaaa
    17461 gcagccaaga aagagaaagg tgcgactgtt tttggctacc aagtgaagga tccagagcgt
    17521 tttggtgtgg ttgagtttga tacagacatg aatgctattt ctatagaaga aaaaccggag
    17581 tatcctcgct ccaactatgc agtgacagga ctgtatttct atgataatga tgttgtggag
    17641 attgctaaac agatcaaacc tagtgctcgt ggcgagttag aaattacaga cgttaacaag
    17701 gcttacctaa atcgtggtga cctttctgtt gagctgatgg ggcgtggttt tgcctggttg
    17761 gatacgggaa cccatgaaag cttgctagaa gcttctcagt atattgaaac ggttcagcgt
    17821 atgcagaacg ttcaagtggc aaatctagaa gaaatttcct atcgtatggg ctacattagt
    17881 cgtgaagacg tgctggaatt ggctcagcct cttaagaaaa atgaatacgg acaatatttg
    17941 ctccgtttga ttggagaagc atagatgtca gataattttt ttggaaagac acttgtggta
    18001 cgcaagattg atgctatacc aggactgcta gagtttgaca ttcccgttca tggagacaat
    18061 cgtggttggt ttaaggaaaa tttccagaag gaaaagatgc taccgcttgg ttttcctgaa
    18121 agcttctttg ctgcagggaa actgcaaaat aacgtcagct tttctcgcaa aaatgttctt
    18181 cgaggactcc atgctgaacc ttgggacaag tatatctctg ttgcagacga tgggaaggtt
    18241 ttaggatctt gggtagattt gcgtgaaggc gagacctttg gaaatgttta ccagacagag
    18301 attgatgcta gcaagggaat ttttgtccct cgtggcgtag ccaacggttt tcaagtcctc
    18361 tcagatacag tttcctatag ctatctggtc aatgactact gggctcttga actcaaaccc
    18421 aaatatgcct ttgttaacta tgctgaccca gcattgggaa ttgagtggga aaacctagcg
    18481 gaagctgagg tttcagaggc agacaaacac catcctctat taagggatgt caaaccactt
    18541 acgaaagacg agttgtaaaa ggaaacatta tgactgaata caaaaaaatt atcgtgacag
    18601 gtggagctgg ttttatcggt tctaactttg tccactatgt ttacaataac tttccagatg
    18661 tccatgtgac agtgctggac aagctgactt atgcaggtaa tcgtgccaat atcgaggaaa
    18721 ttttaggcga ccgtgttgag ttggttgttg gagatattgc tgatgcagcc ttggtagaca
    18781 agttggcggc tgaagcggat gctatcgttc actatgcggc agaaagccac aatgataact
    18841 cgctcaatga cccgagtcca tttatccaca ccaactttat cggaacttac acacttttag
    18901 aagcggctcg taaatacgac attcgtttcc accatgtatc gactgatgaa gtctatggtg
    18961 acctgcctct gcgtgaagat ttgccaggtc atggggaagg cctaggtgag aaatttaccg
    19021 ctgaaaccaa gtacaatcca agctcgcctt actcatcaac caaggctgct tcagacttga
    19081 tcgttaaagc ttgggtgcgc tcatttggtg ttaaagcaac gatttctaac tgttcaaaca
    19141 actatggtcc ataccagcat atcgagaagt tcattccgcg ccagattacg aatatcttga
    19201 gcggtatcaa gccaaaactc tacggagaag gtaagaatgt gcgtgactgg attcacacca
    19261 atgaccattc atcaggcgtt tggacgattc tgaccaaggg tcaaatcggt gaaacttact
    19321 tgatcggtgc tgacggtgag aagaacaaca aggaagtgtt agagctcatt ctcaaggaga
    19381 tggggcaacc cgctgacgct tatgaccatg tgaccgatcg agctggtcac gacttgcgtt
    19441 atgcgattga tgctagcaag ctccgtgatg agttggggtg gaagccagag tttaccaact
    19501 ttgaagcagg cctcaaagag accatcaagt ggtacacaga taaccaagac tggtggaaat
    19561 ctgaaaaaga agcagtagag gctaactatg ctaaaacgca acaagtgatt aaataataag
    19621 atactaaaaa agcaagagac ctcgaggtct cttgcttttc tagtatgtag taagctttta
    19681 ttttcttact tcttgtttat aaaactcttt aagggcatct tgccaggttg ggatgacgaa
    19741 acctgttgcc tttgcctttg ccaaactcat agttgagttg agaggtcgtt tagccttagc
    19801 ggggaacttg ctagagtcta ctggcactac ttcaacatca ctgtccttaa gaatctcgct
    19861 agcaaagtca taccaagtgg tgtcttcagc tgcgtcattt gataagtgat agtagccata
    19921 ctctttttga ttttcagtca cataggtcat gaattcggcc aaggtccgtg tccaagttgg
    19981 gcgaccgtat tggtcgttga ccactgtgag cgttttatgg gttttggcta ggctttgcat
    20041 ggtaaagaca aagttttttc cataatttcc aaaaacccaa gcagtacgaa tgatgtaatg
    20101 ctgtgacgta aggttttcaa caagttcttc tcccattcgc ttggtacgtc cgtactctgt
    20161 ttgcggatca ggtatgtcat cgacttccca ctcttgtcct actggtttct ttccatcaaa
    20221 gacgtagtct gttgagatat agaccagaat agctccgtat ttctcagagg ccttggctac
    20281 attttcagtt ccagttacgt tgatggcaaa atccagttct ttcccttcat cttcggctgc
    20341 atcaacagca gtgtaggctg cacaatgata gactagagtt ggcttaacct cagcaaagac
    20401 tttttcaacc atttcagaat tagtgatatc catttcggtc acatccactg caacatagtc
    20461 cacatttcgc tcatctagta aataacgtag ttcggtacca agttgaccat ttgcacctgt
    20521 aattaagatc atatttttct ccttgatagt tcttatactt aattatatca aaaatataga
    20581 aaaatcggtt tttagtgaac ccttttttgg tataaacttt gttagtgaag cgcaagagag
    20641 ccgaatagtt attactttag aatatcctta aaagtatttt tcagaattta ccaaattaat
    20701 taaaaaattc agaaaattat attgacatct ctctgaaaag agtctataat agagagaaag
    20761 ttttaaagga gaagatgatg aaaagttcaa aactatttgc ccttgcgggt gtaaccttat
    20821 tggcggcgac tactttagct gcatgctctg gatcaggttc aagcactaaa gctgagaaga
    20881 cattctcata catttatgag acagaccctg ataacctcaa ctatttgaca actgctaagg
    20941 ctgcgacagc aaatattacc agtaacgtgg ttgatggttt gctagaaaat gatcgctacg
    21001 ggaactttgt gccgtctatg gctgaggatt ggtctgtatc caaggatgga ttgacttaca
    21061 cttatactat ccgtaaggat gcaaaatggt atacttctga aggtgaagaa tacgcggcag
    21121 tcaaagctca agactttgta acaggattaa aatatgctgc tgataaaaaa tcagatgctc
    21181 tttaccttgt tcaagaatca atcaaagggt tggatgccta tgtaaaaggg gaaatcaaag
    21241 atttctcaca agtaggaatt aaggctctgg atgaacagac agttcagtac actttgaaca
    21301 aaccagaaag cttctggaat tctaagacaa ccatgggtgt gcttgcgcca gttaatgaag
    21361 agtttttgaa ttcaaaagga gatgattttg ccaaagctac ggatccaagt agtctcttgt
    21421 ataacggtcc ttatttgttg aaatccattg tgaccaaatc ctctgttgaa tttgcgaaaa
    21481 atccgaacta ctgggataag gacaatgtgc atgttgacaa agttaaattg tcattctggg
    21541 atggtcaaga taccagcaaa cctgcagaaa actttaaaga tggtagcctt acagcagctc
    21601 gtctctatcc aacaagtgca agtttcgcag aacttgagaa gagtatgaag gacaatattg
    21661 tctatactca acaagactct attacgtatc tagttggtac aaatattgac cgtcagtcct
    21721 ataaatacac atctaagacc agcgacgaac aaaaggcatc gactaaaaag gctctcttaa
    21781 acaaggattt ccgtcaggct attgcctttg gatttgaccg tacagcctat gcctctcagt
    21841 tgaatggaca aactggagca agtaaaatct tgcgtaatct ctttgtgcca ccaacatttg
    21901 ttcaagcaga tggtaaaaac tttggcgata tggtcaaaga gaaattggtc acttatgggg
    21961 atgaatggaa ggatgttaat cttgcagatt ctcaggatgg tctttacaat ccagaaaaag
    22021 ccaaggctga atttgctaaa gctaaatcag ccttacaagc agaaggtgtg actttcccaa
    22081 ttcatttgga tatgccagtt gaccagacag caactacaaa agttcagcgc gtccaatcta
    22141 tgaaacaatc cttggaagca actttaggag ctgataatgt cattattgat atccaacaac
    22201 tacaaaaaga cgaagtaaac aatattacat attttgctga aaatgctgct ggcgaagact
    22261 gggatttatc agataatgtc ggttggggtc cagactttgc cgatccatca acctaccttg
    22321 atatcatcaa accatctgta ggagaaagta ctaaaacata tttagggttt gactcagggg
    22381 aagataatgt agctgctaaa aaagtaggtc tatatgacta cgaaaaattg gttactgagg
    22441 ctggtgatga ggctacagat gttgctaaac gctatgataa atacgctgca gcccaagctt
    22501 ggttgacaga tagtgctttg attattccaa ctacatctcg tacagggcgt ccaatcttgt
    22561 ctaagatggt accatttaca ataccatttg cattgtcagg aaataaaggt acaagtgaac
    22621 cagtcttata taaatacttg gaacttcaag acaaggcagt cactgtagat gaataccaaa
    22681 aagctcagga aaaatggatg aaagaaaaag aagagtctaa taaaaaggct caagaagatc
    22741 tcgcaaaaca tgtgaaataa ctgttgcaaa atataagaaa ggatttagta tttctcttga
    22801 atgctgaatc cttttttaca tttgtaaaga aagattctaa atgtactgac ccccaaaagt
    22861 tggagcctct ttttgtcaga atagagaaaa tttttgttaa ttttacttgt ttcctattgc
    22921 tttctcagtt attatttgtt atattaaaag tataattatt tttatttatc agggttaagc
    22981 attgcacttt cagaggaagg agtatttttt aaaaagaaaa tgtaaacgct tgctcaaaaa
    23041 tgaaaggatt tagaagttta tgaataaagg attatttgaa aaacgttgta aatatagtat
    23101 tcggaaattt tcattaggtg ttgcttctgt tatgattgga gctgcattct ttgggacaag
    23161 tcaggttctt gcagatagcg tgcagtctgg ttccacggcg aacttaccag ctgatttagc
    23221 tactgctctt gcaacagcaa aagagaatga tgggcgtgat tttgaagcgc ctaaggtggg
    23281 agaagaccaa ggttctccag aagttacaga tggatctaag acagaagaag aactattagc
    23341 acttgaaaaa gaaaaaccgg ctgaagaaaa accaaaagag gataaacctg cagttgctaa
    23401 acctgaaacg cctaagacgg taacccctga atggcaaacg gtagagaaaa aagaacaaca
    23461 gggaacagtc actatccgag aagaaaaagg tgtccgctac aaccaactat cctcaactgc
    23521 tcaaaatgat aacgcaggta aaccagccct gtttgaaaag aagggcttga ccgttgatgc
    23581 caatggaaat gcaactgttg atttaacctt caaagatgat tctgaaaagg gcaaatcacg
    23641 ctttggtgtc ttcttgaaat ttaaagatac caataataat gtttttgtcg gttatgacaa
    23701 ggatggctgg ttctgggagt ataaatctcc aacaactagc acttggtata gaggtagtcg
    23761 tgttgctgct cctgaaacag gatcaacaaa ccgtctctct atcactctca agtcagacgg
    23821 tcagctaaat gccagcaata acgatgtcaa tctctttgac acagtgactc taccagctgc
    23881 ggtcaatgac catcttaaaa atgagaagaa gatccttctc aaggcgggct cttatggcaa
    23941 tgaccgtacg gttgtcagcg ttaaaacaga caatcaagaa ggcgtaaaag cggatgatac
    24001 tcctgcccag aaagaaacag gtccggttgt tgacgatagc aaggtgactt atgatacgat
    24061 ccagtctaag gtacttaagg cagtaattga ccaagccttc cctcgtgtca aggaatacac
    24121 cttgaatgga catactttgc caggacaggt gcaacagttc aaccaagtct ttatcaataa
    24181 ccaccgaatc acccctgaag tcacttataa gaaaatcaat gagacaacag cagagtactt
    24241 gatgaagctt cgcgatgatg ctcacttaat caatgcggaa atgacagtac gcttgcaagt
    24301 tgtggacaat caattgcact ttgatgtgac caagattgtc aaccacaatc aagtcactcc
    24361 aggtcaaaag attgatgacg aaagaaaact actttcttct attagtttcc tcggcaatgc
    24421 tttagtctct gtttctagtg atcaaactgg tgctaagttt gatggggcaa ccatgtcaaa
    24481 caatacgcat gtcagcggag atgatcatat cgatgtaacc aatccaatga aggatttggc
    24541 taagggttac atgtatggat ttgtttctac agataagctt gctgctggtg tttggagtaa
    24601 ctctcaaaac agctatggtg gtggttcgaa tgactggact cgtttgacag cttataaaga
    24661 aacagtcgga aatgccaact atgtaggaat ccacagctct gaatggcaat gggaaaaagc
    24721 ttataagggc attgttttcc cagaatacac gaaggaactt ccaagtgcta aggttgttat
    24781 cactgaagat gccaatgcag acaagaacgt tgattggcaa gatggtgcca ttgcttatcg
    24841 tagcattatg aacaatcctc aaggttggga aaaagttaag gatatcacag cttaccgtat
    24901 cgcgatgaac tttggttctc aagcacaaaa tccattcctt atgaccttgg atggtatcaa
    24961 gaaaatcaat ctccatacag atggtcttgg gcaaggtgtt ctccttaaag gatatggtag
    25021 cgaaggccat gactctggtc acttgaacta tgctgatatt ggtaagcgta tcggtggtgt
    25081 cgaagacttc aagaccctaa ttgagaaggc taagaaatat ggagctcatc taggtatcca
    25141 cgttaacgct tcagaaactt atcctgagtc taaatacttc aatgaaaaaa ttctccgtaa
    25201 gaatccagat ggaagctata gctatggttg gaactggcta gatcaaggta tcaacattga
    25261 tgctgcctat gacctagctc atggtcgttt ggcacgttgg gaagatttga agaaaaaact
    25321 tggtgacggt ctcgacttta tctatgtgga cgtttggggt aatggtcaat caggtgataa
    25381 cggtgcctgg gctacccacg ttcttgctaa agaaattaac aaacaaggct ggcgctttgc
    25441 gatcgagtgg ggccatggtg gtgagtacga ctctaccttc catcactggg cagctgactt
    25501 gacctacggt ggctacacca ataaaggtat caacagtgcc atcacccgct ttatccgtaa
    25561 ccaccaaaaa gatgcttggg tagggaacta cagaagttat ggtggtgcag ccaactatcc
    25621 actgctaggt ggctacagca tgaaagactt tgaaggctgg caaggaagaa gtgactacaa
    25681 tggctatgtg actaacctct ttgctcatga cgtcatgact aagtacttcc aacacttcac
    25741 tgtaagtaaa tgggaaaatg gtacaccggt gactatgacc gataacggta gcacctataa
    25801 atggactcca gaaatgcgag tggagttggt agatgctgac aataataaag tagttgtaac
    25861 tcgtaagtca aatgatgtca atagcccaca atatcgcgaa cgtacagtaa cgctcaacgg
    25921 acgtgtcatc caagatggtt cagcttactt gactccttgg aactgggatg caaatggtaa
    25981 gaaactttct actgagaagg aaaagatgta ctacttcaat acgcaggccg gtacaacaac
    26041 ttggaccctt ccaagcgatt gggcaaagag caaggtttac ctttacaagc taactgacca
    26101 aggtaagaca gaagagcaag aactaactgt aaaagatggt aaaattaccc tagatcttct
    26161 agcaaatcaa ccatacgttc tctatcgttc gaaacaaacc aatcctgaaa tgtcatggag
    26221 tgaaggcatg cacatctatg accaaggatt taatagcggt accttgaaac attggaccat
    26281 ttcaggcgat gcttctaagg cagaaattgt caagtctcaa ggggcaaacg atatgcttcg
    26341 tattcaagga aacaaagaaa aagttagtct cactcagaaa ttaactggct tgaaaccaaa
    26401 taccaagtat gccgtttatg tcggtgtcga taaccgtagt aatgccaagg cgagcatcac
    26461 tgtaaacact ggtgaaaaag aagtgactac ttataccaat aagtctctcg ccctcaacta
    26521 tgttaaggcc tacgcccaca atacacgtcg taacaatgct acagttgacg atacaagtta
    26581 cttccaaaac atgtacgcct tctttacaac tggatcggac gtatcaaatg ttactctgac
    26641 attgagtcgt gaagctggtg atcaagcaac ttactttgat gaaattcgta cctttgaaaa
    26701 caattcaagc atgtacggag acaagcatga tacaggtaaa ggcaccttca agcaagactt
    26761 tgaaaatgtt gctcagggta tcttcccatt tgtagtgggt ggtgtcgaag gtgtcgaaga
    26821 caaccgcact cacttgtctg aaaaacacga tccatataca caacgtggtt ggaatggtaa
    26881 gaaagtcgat gatgttatcg aaggaaattg gtcactcaag acaaatggac tagtgagtcg
    26941 tcgtaacttg gtttaccaaa ccatcccaca aaacttccgc tttgaagctg gtaagaccta
    27001 ccgtgtaacc tttgaatacg aagcaggatc agacaatacc tatgcttttg tagtcggtaa
    27061 gggagaattc caatcaggtc gtcgtggtac tcaagcaagc aacttggaaa tgcatgaatt
    27121 gccaaatact tggacagatt ctaagaaagc caagaaggta accttccttg tgacaggtgc
    27181 agaaacaggg gatacttggg taggtatcta ctcaactggc aatgcaagta atactcgtag
    27241 tgattctggt ggaaatgcca acttccgtgg ttataacgac ttcatgatgg ataatcttca
    27301 aatcgaagaa attaccctaa caggtaagat gttgacagaa aatgctctga agaactactt
    27361 gccaacggtt gccatgacta actacaccaa agagtctatg gaggctttga aagaggcggt
    27421 ctttaacctc agtcaggccg atgatgatat cagtgtggaa gaagcgcgtg cagagattgc
    27481 caagattgaa gccttgaaga atgctttggt tcagaagaaa acggctttgg tagcagatga
    27541 ctttgcaagt cttacagctc ctgctcaggc tcaagaaggt cttgcaaatg cctttgatgg
    27601 aaacttatct agtttatggc atacatcatg gggcggagga gatgtaggca agcctgcaac
    27661 catggtcttg aaagaaccaa ctgaaatcac tggacttcgt tacgttccac gtggatcagg
    27721 ttcaaatggt aacttgcgtg atgtgaaact tgttgtgaca gatgagtctg gcaaggagca
    27781 tacctttact gcaactgatt ggccagataa caataagcca aaagacattg attttggtaa
    27841 gacaattaag gctaagaaaa ttgtccttac aggtactaag acttacggag atggtggcga
    27901 taaataccaa tctgcagcgg aactcatctt tactcgtcca caggtagcag aaacacctct
    27961 tgacttgtca ggctatgaag cagctttggc taaagctcag aaattaacag acaaagacaa
    28021 tcaagaggaa gtagctagtg ttcaggcaag catgaaatat gcgacggata accatctctt
    28081 gacggaaaga atggtggaat actttgcaga ttatctcaac caattaaaag attctgctac
    28141 gaaaccagat gctccaactg tagagaaacc tgagtttaaa cttagctcta tagtttccga
    28201 tcaaggtaag acgccagatt ataagcaaga aatagctaga ccagaaacac ctgaacaaat
    28261 cttgccagca acaggtgaga gtcaatctga cacatccctc ttcctagcaa gtgttagtct
    28321 agccctatct gctctctttg tagtaaaaac gaagaaagac tagtatttag taaaacctct
    28381 taacaagatt acggaagcag tctctatctt ttccaatgag gtttatagta cagaaaaagc
    28441 ctgagaagat gtcttctcag gcttttgtta agcacataaa tacaatagtg ctatgacaaa
    28501 atcacccaga aaaatctggg tgataaatgt tatggttgtg ctggttgagg attctgattt
    28561 tgttgatcag gggttgtatt tgattgttgc gtattattgt taggattggt agtcgtacta
    28621 ttatttgtgc ttggagtggt tgagctagac tgtgaagttg aactatctga tgatgagctt
    28681 gaactttcag ttgatggggg ttgttgtgga gcaggtgagt tccacgtaga acgagcacca
    28741 tttttaaata cgaattctcc atttctgtag agcccctctg gtatattcca atcttctgga
    28801 ttgcttcctt cagacaggta ggtcatcata gagcggtaaa ctttggcagc gaccgtaagg
    28861 ccattgccta caagtggtgt cagacggtta gaatagcctg tccatacagc cattgaatat
    28921 ttacgcgtat agccagcaaa tagttcatca ggtgctacaa attgagaggt cttgatgtgg
    28981 ttttcaattt cctcgtctgt atagttagag gttcctgttt taccagcctg agggagccaa
    29041 gcaagatagg catttcgtcc agttccataa gtcaagactg ttttcatcat gtcggtcatc
    29101 atataggctg tcgtttcttt catggcacga gttccgacat tagagaactc tttttcactc
    29161 ccatcactaa agacgacttt atggatatac attggtttat agtaagttcc accatttgca
    29221 aaggcagcgt aagcagcagc catcttttca ctacttgctc catatttttt gtctgattcg
    29281 gttgtgttac ttgaaatggc atttgagtag tgaatacttg ggtagtcgat tccgagacca
    29341 tttaggaaag tcttggcgcg gttgagtccg accttgttta gagtttccac ggctgggacg
    29401 tttcgcgatt gttgcagggc gtattgcaag gtgatgttgc caaagtagcc cctatcccag
    29461 ttataaacag gagtatttgt cccagggtaa ttatagggct catcgtgaac gatagtagca
    29521 gttgaatcgt agacaccgta ctccaaggca ggagcatagt ctgtgatcgg tttcatagtt
    29581 gatccccagt cgcggtttgt ttctactgct tggttaattc cgaaggaaac attacttgac
    29641 tgatggcgtg ctcctagctg ggcaatgact ttaccgttag aaacatcaac aatggtagaa
    29701 gcgacttgca attcatcgtc tggataggca acgtattcgt ctgtattgta aatatcccac
    29761 agatgttttt gagcttcttg gtctacattt gtgtagacat ccatcccagt tgtgagcagg
    29821 ttatagcctg tttcttcttc aacttgattg atgacttcct tgaggtaatt atccatgtaa
    29881 gcagggtaat tacttgctga tttgagactt tgtagtccat cagtaattgg tgtattgact
    29941 gctttctcat actgttcagc agagatgtag ccttgatttt tcatttcaga taagaccaag
    30001 tttcggcggt cttgggctgc ttctggatgt gaataggggt catattggtt tggtgcctga
    30061 ggcattccag ccagcaaggc taactgaggt aaacttaaat tattgaggtc tttaccatag
    30121 tagttttgag ctgctgtctg cattccatag ttcccattag acatgtagac cttatttata
    30181 tagtaggtca agatttcttg cttggttgct ttttgttcta actgaatcgc taaccaagct
    30241 tcctgagcct tacgagaaat agtctggtcg gaagtcgaag ttgaaaagta agtcaactta
    30301 atcaactgtt gggtgagagt tgatccacct tggagggaat tgctttgcag attgcgcaag
    30361 aaagctccca ggatacggat ggtatcaatc cccctgtggt cgaagaagcg atggtcttcg
    30421 atagaaacga ttgccttaac caaatctgtg ggaatatcat tagcttgggc attgacgcgg
    30481 cgttcagaac ccaagtcagc aatgagttga tttttattgt cgtagatttt actagaagtt
    30541 gttgcaacta gtttactctc ggataggcta ggagccttgc taacgtagta gaaaaaaact
    30601 cctccgccta agacaatggc tgcgataacc aagcttaaga agctaatgct cagatacttg
    30661 attaggcgca gaatcgttgg tttgttcatc ttgttttacc acctaataaa tgttctttga
    30721 taacattgag ataaggaatt tgagggaagg caccagcctt gatttcatat ccatattctc
    30781 gaatatattc aagtggcatt gatttttgtc ccttatcttg atgatagaag cgaatcaaat
    30841 cgaatgccgg caataagtag gtttcttgct gagaagaaaa gtgaagaagg acaaagcaga
    30901 ttccttgttg ggcaaggact tgttccatat gctgaatctg atgtggatga aaatttttca
    30961 tcggaatcgc acgtttttgt tttgtttcct tgacttcaaa gtcgatgtaa tatccattat
    31021 aaacgccaga atagtccgtc gttgaagctt gtcgaaaata ggcttcaaca atcttggcac
    31081 gacttcgttg tggatagtcc acttgtacga tttgaatagg agttggtttc ttatgtataa
    31141 cagccaagcc ctgagacaaa tagtagtcgt tggtagcatt gatcatcttt tcaaaagaca
    31201 ttcctcgatt tgcgaaattt ttgggttgag aaagagatgt ttgccttttt tgtgatgaaa
    31261 ctttatgtgg atagttgacc ataattctcc ttattggtac aataacatca ctttattata
    31321 ccataatttg cacagaaagg gttaaaaatg gctacagctt tggttttagg ctattctgct
    31381 tttgatttgg gtttattttc tgataaggat cctcgtctta aattgattaa aaaagcgata
    31441 cgtaaagatt tagaggctat ggcagcagat ggggtgtctt ggcttgtgtt tacaggaagt
    31501 ttgggttttg aatattgggt tttagaggtt gctcaggaga tgaaaaccga atacggtttc
    31561 cagttggcca ccatttttgc ttttgaaaac catggggaaa attggaatga aggcaatcag
    31621 atgaaactga gtcgctttaa gcaggtagac tttgtcaaat atgcttatcc tcgttatgaa
    31681 cacaaggggc agttaagaga ttatcagcag tttttgctgg aaaacacgac tagttcctat
    31741 cttttttatg atgaagaaaa tgaaacaaaa ctagcttatt tttaccaaaa gatgaaaaat
    31801 caagaggact attttataaa gagattaaca tttgatgaat taaatgaact tgctgaaaat
    31861 ttttccgaaa attgaagctt tgaccttgat ttttgtttgc ctttttttat ataataatac
    31921 tagcaagcga gaatggagag agacatggca agtattattt tttcagcgaa agatattttt
    31981 gaacaagagt ttggacgtga agtccgtggc tataataaag tagaagttga cgagttttta
    32041 gacgatgtca tcaaggacta tgaaacctat gctgccttgg tcaagtcact tcgtcaggaa
    32101 attgcggatt tgaaggaaga attaactcgt aaaccgaaac cttcaccagt tcaagcagaa
    32161 ccccttgaag cggcaattac aagttctatg acgaattttg atattttgaa acgcctgaat
    32221 agattggaaa aagaagtttt tggtaaacaa attttagata actcagattt ttaagtagtt
    32281 atttgagatg tgcaattttt ggataatcgc gtgaggagaa ttgcttctca tgaggaaagt
    32341 ccatgctagc acaggctgtg atgcctgtag tgtttgtgct aggcgaaacc ataagcctag
    32401 ggacgaggaa tcgttacggc agttgaaatg gctaagtcct tggataggcc agagtaggct
    32461 tgaaagtgcc acagtgacgg agtctttctg gaaacagaga gagtggaacg cggtaaaccc
    32521 ctcaagctag caacccaaat tttggtcggg gcatggagta cgcggaaacg aacgtagtat
    32581 tctgactgct atcagctaga gctgttagtg gtagacagat gattatcgaa ggaagtggtc
    32641 ctagtcactt ctggaacaaa acatggctta tagaaaattg catataggtt ggggctgaga
    32701 aattttctca acctcatttt ttaaagtgga catatagaaa ggtcttgcaa gactgtaaca
    32761 tgaaaaaaga atttaattta attgcaactg tggcagcagg gcttgaggct gtcgttggtc
    32821 gtgaagtgcg agagttgggc tacgattgtc aggttgaaaa tggacgtgtt cgttttcaag
    32881 gagacgtgag agctattatc gaaaccaacc tttggcttcg ggcagcagat cgtatcaaaa
    32941 ttatcgtagg aacgttccca gctaagactt ttgaagagct atttcaggga gttttcgctt
    33001 tagattggga aaattattta ccacttggag ctcggttccc gatttcaaaa gctaaatgtg
    33061 ttaagtccaa acttcacaat gagcctagtg ttcaggctat ttctaagaaa gctgttgtca
    33121 agaaattgca gaaacactat gctcgcccag aaggggttcc tctgatggag aatggcccag
    33181 agtttaagat tgaggtctct attctcaaag atgtggcaac tgtcatgatt gatacgaccg
    33241 ggtctagcct ctttaaacgt ggttatcgta ccgaaaaagg tggcgctcct atcaaggaaa
    33301 atatggcagc agccatttta caactttcta actggtaccc agacaagcct ttgattgatc
    33361 cgacctgtgg ttcggggact ttctgtattg aggcagttat gattgctaga aagatggcgc
    33421 caggtcttcg tcgctctttt gcatttgagg aatggaactg gatcagcgat cgcttgattc
    33481 aagaagtgcg cacagaagcg gctaaaaaag tagaacgtaa gcttgagttg gatatcatgg
    33541 gctgtgatat tgatgctcgc atggtggaaa ttgctaaggc caatgctcag gcagctggtg
    33601 ttgcaggaga tattactttt aagcagatgc gcgtgcagga tttacgttcc gataaaatca
    33661 atggagtaat catttccaat ccgccttatg gtgaacgttt gtcagatgat gcaagggtga
    33721 ccaagctcta tgctgagatg gggcaagtat ttgcaccgct gaaaacttgg agcaaattta
    33781 tcctgactag tgatgaagct tttgaaagca agtatggtag ccaagcagat aagaagcgta
    33841 agttatacaa cggaaccttg aaagtggatc tatatcaata ttttggtcag cgtgtcaaac
    33901 ggcaagaggt aaaatagaaa gggatactca tgagtaaaaa aagacgaaat cgtcataaaa
    33961 aagaaggtca agaaccgcaa tttgattttg atgaagcaaa agagctaaca gttggtcaag
    34021 ctattcgtaa aaatgaagaa gtggaagcag gagtcttgcc tgaggattcc attttggaca
    34081 agtatgttaa gcaacacaga gatgaaattg aggcggataa gtttgcgact cgtcaataca
    34141 aaaaagagga gttcgttgaa actcagagtc tggatgattt aattcaagag atgcgtgagg
    34201 ctgtagagaa gtcagaagct tcttcggagg aagttccatc ttctgaagac atcttactac
    34261 ccttgcctct ggacgatgag gagcaaggct tggatcctct attgctagag gatgaaaatc
    34321 caacagaaat gactgaagaa gtggaagagg agcaaaacct ttctcgtctg gatcaagagg
    34381 actcagaaaa gaaaagtaaa aaaggcttta ttttgaccgt tttggcgctt gtatcagtaa
    34441 ttatttgtgt cagtgcttat tatgtctacc gtcaagtggc tcgttcgacc aaggaaattg
    34501 aaacttctca atcaactaca gccaatcaat cggatgtgga tgattttaat acactttatg
    34561 acgcctttta cacaaatagc aataaaacgg ctttgaaaaa tagccagttt gataaactga
    34621 gtcaactcaa aaccttgctt gataaactgg aaggtagtcg tgaacatacg cttgccaaat
    34681 ctaaatatga tagtctagca acgcaaatca aggctattca agatgtcaat gctcaatttg
    34741 agaaaccagc tattgtggat ggtgtgttgg ataccaatgc caaagccaaa tcggatgcta
    34801 aatttacgga tattaaaact ggaaatacgg agcttgataa agtgctagat aaggctatca
    34861 gtcttggtaa gagccagcaa acaagtactt ctagctcaag ttcaagtcaa actagcagct
    34921 caagctctag tcaagcaagt tcaaatacga ctagtgagcc acaaccaagt agttcaaatg
    34981 agactagaag tagtcgcagt gaagtcaata tgggtctctc gagtgcaggg gttgctgttc
    35041 aaagaagtgc cagtcgtgtt gcctataatc agtctgctat tgatgatagt aataactctg
    35101 cctgggattt tgcggatggt gtcttggaac aaattctagc gacttcacgt tcacgtggct
    35161 atatcactgg agaccaatat atccttgaac gtgtcaatat cgttaacggc aatggttatt
    35221 acaacctcta taagccagat ggaacctatc tctttaccct taactgtaag acaggctact
    35281 ttgtcggaaa tggcgctggt catgcggatg acttggacta ctaagcagtc gttacaaaat
    35341 tctttctttt caaaagtaaa aatgataaaa taaaacaaat gaaacaagag gagtgtcaaa
    35401 tgacaaaagc taactttggt gtcgtaggta tggccgtaat gggtcgtaac cttgccctta
    35461 atattgaatc acgtggttac acagttgcta tctacaaccg tagtaaagaa aaaacggaag
    35521 atgtgattgc ttgccatcct gaaaagaatt ttgtaccaag ctatgacgtt gaaagttttg
    35581 taaactcaat cgaaaaacct cgtcgtatca tgctgatggt tcaagctgga cctggtacag
    35641 atgctactat ccaagccctt cttccacacc ttgacaaggg tgatatcttg attgacggag
    35701 gaaacacttt ctacaaagat accatccgtc gtaatgaaga attggtaaac tcaggtatca
    35761 actttatcgg tactggagtt tctggtggtg aaaaaggtgc ccttgaaggt ccttctatca
    35821 tgcctggtgg acaaaaagag gcctacgaat tggttgcgga tgttcttgaa gaaatctcag
    35881 ctaaagcacc agaagatggc aaaccatgtg tgacttacat cggccctgat ggagctggtc
    35941 actatgtgaa aatggttcac aatggtattg agtacggtga tatgcaattg atcgcagaaa
    36001 gctatgactt gatgcaacac ttgctaggcc tttctgcaga ggatatggct gaaatcttta
    36061 ctgagtggaa caagggtgaa ttagacagct atttgatcga aatcacagct gatatcttga
    36121 gccgtaaaga cgatgaaggc caagatggac caatcgtaga ctacatcctt gatgctgcag
    36181 gtaacaaggg aactggtaaa tggactagcc aatcatctct tgaccttggt gtaccattgt
    36241 cactgattac tgagtcagtg tttgcacgct acatttcaac ttacaaagaa gaacgtgtac
    36301 atgctagcaa ggtgcttcca aaaccagctg ccttcaactt tgaaggagac aaggctgaat
    36361 tgattgaaaa aatccgtcaa gccctttact tctcaaaaat catttcatac gcacaaggat
    36421 ttgctcaatt gcgtgtagcc tctaaagaaa acaactggaa cttgccattt gcagatatcg
    36481 catctatctg gcgtgatggc tgtatcatcc gttctcgttt cttgcaaaag attacagatg
    36541 cttacaaccg cgatgcagat cttgccaacc ttcttttgga cgagtacttc ttggatgtta
    36601 ctgctaagta ccaacaagca gtacgtgata tcgtagctct tgcggttcaa gctggtgtgc
    36661 cagtgccaac tttctcagca gctattactt actttgatag ctaccgttca gctgaccttc
    36721 cagctaactt gatccaagca caacgtgact actttggtgc tcacacttac caacgtaaag
    36781 acaaagaagg aaccttccac tactcttggt atgacgaaaa ataagtaggt cagccatggg
    36841 gaaacggatt ttattacttg agaaagaacg aaatctagct cattttttaa gtttggaact
    36901 ccagaaagag cagtatcggg ttgatctggt agaggagggg caaaaagccc tctccatggc
    36961 tcttcagaca gactatgatt tgatgttatt gaacgttaat ctgggagata tgatggctca
    37021 ggattttgca gaaaaattga gccgaactaa acctgcctca gtcatcatga ttttagatca
    37081 ttgggaagac ttgcaagaag agctggaagt tgttcagcgt tttgcagttt catacatcta
    37141 taagccagtc cttatcgaaa atctggtagc gcgtatttcg gcgatcttcc gaggtcggga
    37201 cttcattgat caacactgca gtctgatgaa agttccaagg acctaccgca atcttaggat
    37261 agatgttgaa catcacacgg tttatcgtgg tgaagagatg attgctctga cccgccgtga
    37321 gtatgacctt ttggcgacac ttatgggaag caagaaagta ttgactcgtg agcaattgtt
    37381 ggaaagtgtt tggaagtatg aaagtgcgac cgagacaaat atcgtagatg tctatatccg
    37441 ctatctacgg agcaagcttg atgttaaagg acaaaaaagc tacattaaaa ctgtgcgtgg
    37501 tgttggatat accatgcaag aatagaaaag cagttgcagt tgtgtaactg cttttttgag
    37561 gagtttttat atattgacat gcagtcgggt ctttgctaca atcgttttag gaggatatat
    37621 agatgaaact tttgaaaaaa atgatgcaag ttctactagc agtctttttc tttggtttgc
    37681 tagggaccag tacagtattt gcagatgatt ctgaaggatg gcagtttgtc caagaaaacg
    37741 gaagaaccta ctacaaaaag ggggacctca aagaaaccta ctggcgagtg attgatggta
    37801 agtactatta ttttgattct ctatctggag agatggttgt cggttggcaa tacttagaaa
    37861 ttcctggaac aggttatcgt gatgatttat ttgataatcg tccagtcttc gaaattggcc
    37921 ttcaggagaa gtggtactat tttggacaag atggtgcttt gctagaacaa acagataaac
    37981 aagtactaga ggcaaaaacg tctgaaaata caggaaaagt atacggtgaa caatatcctc
    38041 tatctgctga aaagagaact tattattttg ataataatta tgctgtaaag acaggctgga
    38101 tttatgaaga gggtcattgg tattatttaa ataagctagg aaattttggc gatgattctt
    38161 acaatccact accaattggt gaagttgcta agggttggac tcaagatttt catgttacta
    38221 ttgacattga tagaagcaaa cctgctccat ggtactacct agatgcttca ggtaagatgc
    38281 ttacagattg gcaaaaagta aacggaaaat ggtattattt tggctcctct ggttctatgg
    38341 caacaggttg gaaatatgta cgaggcaaat ggtattactt agataataaa aatggtgata
    38401 tgaaaacagg atggcaatac cttggtaaca agtggtacta tcttcgttca tcaggagcaa
    38461 tggcaactgg ctggtatcaa gatggttcaa cttggtacta tttagatcct tctaatggag
    38521 atatgaaaat aggttggaca aaagtaaatg gaaaatggta ttatctcaat tcaaatggag
    38581 caatggttac aggtagtcaa actatcgatg gtaaagttta taatttcgcc tcatccggtg
    38641 agtggattta atattggagg gtatatagat gaaaattttg aaaaaaatga tgcaagctgg
    38701 actaacagta attttctttg gtttgctagc tacgaataca gtatttgcag ataactctga
    38761 aggatggcag tttgtccaag aaaacggtag aacctattac aaaaaggggg acctcaaaga
    38821 aacctactgg cgagtgattg atggtaagta ctattatttt gattctctat ctggagagat
    38881 ggttgtcggc tggcaatata tcccgtttcc atctaaaggt agtacaattg gtccttaccc
    38941 aaatggtatc agattagaag gttttccaaa gtcagagtgg tactacttcg ataaaaatgg
    39001 agtgctacaa gagtttgttg gttggagaac attagagatt aaaactaaag acagtgttgg
    39061 aagaaagtac ggggaaaaac gtgaagattc agaagataaa gaagagaaac gttattacac
    39121 gaactattac tttaatcaaa atcattcttt agagacaggt tggctttatg atcagtctaa
    39181 ctggtattat ctagctaaaa cagaaattaa tggagaaaac tatattggtg gtgaaagacg
    39241 tgcaggttgg ataaatgatg cttcagcttg gtactaccta gatccagcaa ctggtattat
    39301 gcaaacaggt tggcaatatc taggtaataa gtggtactac ctccgttcct caggagcaat
    39361 ggccactggc tggtatcagg aaggtaccac ttggtattat ttagaccacc caaatggcga
    39421 tatgaaaaca ggttggcaaa accttgggaa caaatggtac tatctccgtt catcaggagc
    39481 tatggcaact ggttggtatc aagatggttc aacttggtac tacctaaatg caggtaatgg
    39541 agacatgaag acaggttggt tccaggtcaa tggcaactgg tactatgctt atagctcagg
    39601 tgctttggca gtgaatacga ccgtagatgg ctattctgtc aactataatg gcgaatgggt
    39661 tcggtaatga cagggcgctt ataattatat tagaacactc gcttaatcaa agaagtgact
    39721 ttgttgtact tgacctgacg attggggaga ttaaaagcat gtgaaatcta cacatgcttt
    39781 ttcgttagtt atgagtgttg aacttgacta accattgaca aaagataaga gcaatcaaaa
    39841 taagatacaa aaatatcaat gctaactgca ccgaaacgcc cgatgctatg gatagggcta
    39901 atagggagag cagggacggg gcgagaatgt ctactgtgct cagagcagag cccaccgtcc
    39961 ccatcttgtc actggggata tgggcaaaga cagctgcttg taggcgaggg ctgagaatgc
    40021 cgataatcgt agaactgatg aaactggtca cgaaaattac gatataggct tgacaaagga
    40081 tactagttat tagagccaat agggaaatct cacagaaaac caagaggtgc gtgaaacgga
    40141 tatttttaaa tagattactg ctggtcatat tgccaaggat agctccacaa gacatgatga
    40201 tggagagcag ggcgaagagt tgcccaatgc tcagttgtgc tagtgtctgt tggatgaagc
    40261 ggagggcaat cagccgaggg gacacatcca agatggcaat catactggtc gtcagaaaca
    40321 gtagtatgac ggtatctttt aacctcagga gcacagccag cgactgttta agatgttgaa
    40381 aatatttctt aaaactcagt gctgtatgtg acatttcaat ccttttttca acctcataca
    40441 aggtatgtcg aataacatac aggcccaaaa aggcaatgac aaaagtcaga gtgttgataa
    40501 gggaaatagt ttgaatactt ataacattga taaggaatgc accagccaga ttggcgacaa
    40561 tgcggacaac cctcatcaga gactgcctga accccatggc atcatgcagg tcgtccttaa
    40621 ttacactgat gtagagggcg ttcatcatgt aggcagacag gtagctcaag gtgtcagaga
    40681 tgaggttgat gatgacaatc ataatgactg aaactaatga aaagggcgac aagacgagaa
    40741 atactgtcaa aatagcgtag agcaggattt tgattttggc aatacagagt gcgtgtttga
    40801 ctctattttc ttgaaaatct cctagaatcc cgagaaagag ttgcgatagt aggggaacca
    40861 tctctgaaat ggaaatcagt aaaattgcta gcggagcgaa attgtactga gccacataat
    40921 tgataatggc gaggtagaaa atactgtcgc cgaatgatga aaaacagctg tttagcagca
    40981 actgtctata tatgttgttt gtccaaaata atttcatact tttctcctta tgtctgcaca
    41041 tcgaatggga atttattatt taatagacac caatataccc ccatgcttcc tattccgaag
    41101 tcaaacaaat ctactttacc actatctcct tgaaacatca gtaaaccgtg atcatctcgt
    41161 tcagaacatg ctaaaattac ctgttggatt tttttcatca gtaatttgtt ttgattgtag
    41221 acagtggttt gtagtaagct agttattccg tggcaatatc ctgtcatcat ttttagatga
    41281 tggttaaaaa caaattcttg atatttacta ataatatctt tgtttccgtc acaatcgtac
    41341 atacaaagat ataagattat tccggaaatt ccttcgcacc aagaaagttg taaatttcct
    41401 aaattttcag tattagaagt aactttttct aataattttt ttaattcagc atggaatgta
    41461 tggagatcat tatagaacat agaaggttct aagactttag aataggcaaa taaagcatat
    41521 gcaattccac aatatccatg agcaaagcta tagtctaaaa tgctttcttt ggctgtatct
    41581 ctttgtagga aataatgata aatttcccca tatactattg tggatgaaag ttttaagagt
    41641 attgtcattg gtaaattgat agtattttat taatgataat aggacaccag attttcccaa
    41701 tgcaaagtct atttcctcta gagtatcata attctctatt aatttcttag cggtgacgtt
    41761 tgctaattgt agatagtatt gatttttact gatagaaaat aaatgtagga gtaaccatag
    41821 atagcctgca tcaccaaata gcagtgagta ttgatattca tatgtgtgtg tcgttctaat
    41881 tgtcactgcc ttcttgatga tagagagtat tttagaatcc agttctgggg ggtacaattt
    41941 atttagagga aacagtagtc cagctattcc gtgttggaat gataaattac ttacgaaatt
    42001 tccaaattct gttgaagaag tgatccttcc ttcagaattt acagttttat ctagtaaaaa
    42061 tcgtagaaca ctattacatt ctgttttgta atcatattta tgttcctcta tttttttaat
    42121 tttgactaaa ttatttgttt gacttaaatt tagtagatat tgtaaccaaa atagttgctc
    42181 atctgtgagc tgaccttgag tatgtgatag ttctagtaat tgaataggat cctttaggta
    42241 gattcaatca atctataaca caacaacata ataatacttt taggataact tgtcaaatat
    42301 tatagtaaaa tgaaataa
//
LOCUS       DAVLCS010000014        41866 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLCS010000014 DAVLCS010000000
VERSION     DAVLCS010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41866
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.014"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            658..1140
                     /locus_tag="VXC78_000863"
     CDS             658..1140
                     /locus_tag="VXC78_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEV0582973.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            1137..1733
                     /locus_tag="VXC78_000864"
     CDS             1137..1733
                     /locus_tag="VXC78_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0582974.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            1714..2205
                     /locus_tag="VXC78_000865"
     CDS             1714..2205
                     /locus_tag="VXC78_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0582975.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            2585..4738
                     /locus_tag="VXC78_000866"
     CDS             2585..4738
                     /locus_tag="VXC78_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0582976.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            4751..6100
                     /locus_tag="VXC78_000867"
     CDS             4751..6100
                     /locus_tag="VXC78_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV0582977.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            6270..6977
                     /locus_tag="VXC78_000868"
     CDS             6270..6977
                     /locus_tag="VXC78_000868"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0582978.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            7034..10759
                     /locus_tag="VXC78_000869"
     CDS             7034..10759
                     /locus_tag="VXC78_000869"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV0582979.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVVSDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            10852..12294
                     /locus_tag="VXC78_000870"
     CDS             10852..12294
                     /locus_tag="VXC78_000870"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV0582980.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            12513..13535
                     /locus_tag="VXC78_000871"
     CDS             12513..13535
                     /locus_tag="VXC78_000871"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV0582981.1"
                     /translation="MANKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIAGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            13532..14077
                     /gene="purN"
                     /locus_tag="VXC78_000872"
     CDS             13532..14077
                     /gene="purN"
                     /locus_tag="VXC78_000872"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV0582982.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            14161..14670
                     /locus_tag="VXC78_000873"
     CDS             14161..14670
                     /locus_tag="VXC78_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0582983.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            14695..16242
                     /gene="purH"
                     /locus_tag="VXC78_000874"
     CDS             14695..16242
                     /gene="purH"
                     /locus_tag="VXC78_000874"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV0582984.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            16364..17626
                     /gene="purD"
                     /locus_tag="VXC78_000875"
     CDS             16364..17626
                     /gene="purD"
                     /locus_tag="VXC78_000875"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV0582985.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTAIYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQLILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            18029..18517
                     /gene="purE"
                     /locus_tag="VXC78_000876"
     CDS             18029..18517
                     /gene="purE"
                     /locus_tag="VXC78_000876"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV0582986.1"
                     /translation="MKPVISIIMGSKSDWATMQKTTEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            18504..19595
                     /gene="purK"
                     /locus_tag="VXC78_000877"
     CDS             18504..19595
                     /gene="purK"
                     /locus_tag="VXC78_000877"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV0582987.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            19605..19832
                     /locus_tag="VXC78_000878"
                     /pseudo
     CDS             19605..19832
                     /locus_tag="VXC78_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
     gene            19895..21193
                     /gene="purB"
                     /locus_tag="VXC78_000879"
     CDS             19895..21193
                     /gene="purB"
                     /locus_tag="VXC78_000879"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV0582988.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(21248..25186)
                     /gene="strH"
                     /locus_tag="VXC78_000880"
     CDS             complement(21248..25186)
                     /gene="strH"
                     /locus_tag="VXC78_000880"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0582989.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMDFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQEEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(25501..26217)
                     /locus_tag="VXC78_000881"
     CDS             complement(25501..26217)
                     /locus_tag="VXC78_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0582990.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            26565..28352
                     /locus_tag="VXC78_000882"
     CDS             26565..28352
                     /locus_tag="VXC78_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV0582991.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            28349..28825
                     /locus_tag="VXC78_000883"
     CDS             28349..28825
                     /locus_tag="VXC78_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0582992.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            28853..29758
                     /locus_tag="VXC78_000884"
     CDS             28853..29758
                     /locus_tag="VXC78_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0582993.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            29745..30560
                     /locus_tag="VXC78_000885"
     CDS             29745..30560
                     /locus_tag="VXC78_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0582994.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            30567..30971
                     /locus_tag="VXC78_000886"
     CDS             30567..30971
                     /locus_tag="VXC78_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0582995.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            31270..32436
                     /locus_tag="VXC78_000887"
     CDS             31270..32436
                     /locus_tag="VXC78_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV0582996.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESLATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            32552..33589
                     /locus_tag="VXC78_000888"
     CDS             32552..33589
                     /locus_tag="VXC78_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV0582997.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            33797..34651
                     /locus_tag="VXC78_000889"
     CDS             33797..34651
                     /locus_tag="VXC78_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0582998.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            34788..35045
                     /locus_tag="VXC78_000890"
     CDS             34788..35045
                     /locus_tag="VXC78_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV0582999.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(35087..35449)
                     /locus_tag="VXC78_000891"
     CDS             complement(35087..35449)
                     /locus_tag="VXC78_000891"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583000.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDGTDEVSSKHCFEVVDRTDEVS
                     NHIYGKVKLTWFEEIFEEYKSLHNKTHITKVLMNCTPKVRQKKSNFWGSVHSTPDTMR
                     FFNFRDFLQLLLTHIKLF"
     gene            complement(35503..35799)
                     /locus_tag="VXC78_000892"
     CDS             complement(35503..35799)
                     /locus_tag="VXC78_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0583001.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(35789..35950)
                     /locus_tag="VXC78_000893"
     CDS             complement(35789..35950)
                     /locus_tag="VXC78_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV0583002.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            36020..36784
                     /locus_tag="VXC78_000894"
     CDS             36020..36784
                     /locus_tag="VXC78_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV0583003.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(37024..37176)
                     /locus_tag="VXC78_000895"
     CDS             complement(37024..37176)
                     /locus_tag="VXC78_000895"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583004.1"
                     /translation="MRTKASLRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTAR"
     gene            37394..38773
                     /locus_tag="VXC78_000896"
     CDS             37394..38773
                     /locus_tag="VXC78_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0583005.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            38787..39452
                     /locus_tag="VXC78_000897"
     CDS             38787..39452
                     /locus_tag="VXC78_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV0583006.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            39566..39661
                     /locus_tag="VXC78_000898"
                     /pseudo
     CDS             39566..39661
                     /locus_tag="VXC78_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            39807..40345
                     /locus_tag="VXC78_000899"
                     /pseudo
     CDS             39807..40345
                     /locus_tag="VXC78_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            40412..40822
                     /locus_tag="VXC78_000900"
     CDS             40412..40822
                     /locus_tag="VXC78_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV0583007.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            40938..>41866
                     /gene="pavB"
                     /locus_tag="VXC78_000901"
     CDS             40938..>41866
                     /gene="pavB"
                     /locus_tag="VXC78_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV0583008.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASLAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNV"
BASE COUNT        11642 a         7977 c         9589 g        12658 t
ORIGIN      
        1 taatttatgt catactactc aattatttta ttttagtcat ggggatatta gataatcatg
       61 cgagtaattt ctattttaaa agcagtcgaa tgagtcaaaa aagatttcgt agcagtctat
      121 ttatattgct tcgtttttgt tggttaaata aagggttaac tttttctttt attttgatta
      181 gtattcttct ttcctatcta ttctattttg gtatatgatg acgatgttat caattgatga
      241 cacaaaaata ccaatattat ttctttatac ctcaatatat attacattaa tggaggcaat
      301 aatagggaat cataaatcct caattggggt agatctagct ttacttcaat tatctgctct
      361 taatcattct aaaatgaatt tcttttttaa gaatgcacaa ctaatgatgt tgacgcattt
      421 aatctctttc ttacaatttt cattgttgtt atgtttgatt ccggtgacaa gttatagtaa
      481 tgatataaaa agtattttgt tgaatttgtt attgattcca ttcaattatt ttatagccta
      541 tgtctattat aagaaagctc tatttttaat taaaggtaca gttagtttat tgagatggag
      601 ttttctggtt ttatattgtt ttctgataat atttgtaatt ttagtagggg gcattagatg
      661 agaaaaagtg gttttctgat ttactatgtg ttattttgta tagtctgttt tttactaggt
      721 ttacttttaa gctttatatt aaaaaatgag acttttgcta ctatacctcc gaaactggaa
      781 ttacaattta cattgacagt tttacaggca aattctacaa attttttgct atatctattc
      841 tgttttccga tttcgccctt attgcaactt tttgatttgc tatctttagg aatacaattg
      901 ggtatatctg gtcagatgat tggaatagta gctacaataa aaggaatatt acctcatgct
      961 cttattgaaa taccgaattt tatttggtat caaggtatga gtcagtatct tttataccga
     1021 ttattgaagg ataggggaat taaaaatata cttatttata taaaaagtaa tttaaaatgg
     1081 tatatcattt cttatctttt attaatttta gcagcgttga tagagggaat taaattatga
     1141 aaattgaaaa tgaatctaaa agttatgata aatgtatatt gaaaaatata tcactagaga
     1201 ttgataaggg aatttacaga gttgaaggag agaatggttc aggaaagagc acccttctac
     1261 aacttttagc tgggctagag acttttgata gtggtttaaa gaattgtgtc tccaaagatg
     1321 tactatacct tgataccaat cagcttgggg ttgttccatt tactatagaa gaaaatttgc
     1381 agttgttgtg tgattctttt caaatccatc tatcatttga ggataaagaa caaattaata
     1441 ctttttttga taataaaatc ggagataact atatgacagc atctactgga acaaaattca
     1501 aattaggctt atccttaatt tttgctaaaa attgggatta tatttttatt gatgagactt
     1561 tatcaacagt ggatgcaaga agtattgata tgattgctaa acgcttaatt tccatgaaag
     1621 aaagctctac tattatatat gtatctcata atttattgaa tcaagaattg attagcaaat
     1681 ctcaaaggat tttaatagag gaaggacggg tttatgaaat ttcaaacaaa taatagttta
     1741 tacaaattaa tgaatctgat tatttatctt tttcttttat atttgtttat tgatttactg
     1801 atgaagtcgg gaattttaga tgaacaaatt gataaattat ctgaactatc taatcttttt
     1861 acaattaaaa tagaaacaat attgacagtg atttctgttg ttttcacatt tatagcaact
     1921 cttattgaat atggattttc tctctttctg attacattat tttttgataa gaataagagg
     1981 aactttggag atattctttt atctaaaaat ataaccttaa gttttagcat tttactttgt
     2041 tatttattta atccatcgga tataaagttt gcctatttca gcgtattgac agtattacta
     2101 attgggataa caaattatgc gagatttaaa aatttaagat tgacagtagt gttttctgta
     2161 ccatttttat ttaatgctat aatgtctatt ataaatagtt tttagaaata ctaaaatttt
     2221 tttctttact taataatgat atgaaatcat ttcggttttg ttaacttgta attcttatat
     2281 tttctaggta gaacgtttgt tctgcctatt tttttatcca aaaagtgcag ttgggaggga
     2341 gataggctca tttgggaagg aagtccagtt tttgtttagt gattggggta agatagttgt
     2401 tatcagatga gtttatactc ttcgaaaatc aaattcaaac cacgtcaacg tcgccttgcc
     2461 gtatatatgt gactgacttc gtcagtccta tctacaacct caaaacagtg ttttgagcag
     2521 cctgcggcta gtttcctagt ttgctctttg attttcattg agtattaggg aaaaggagat
     2581 gaatatgaaa tttgggaaac gtcactatcg tccgcaagtg gatcagatgg actgcggtgt
     2641 agcttcatta gccatggttt ttggctacta tggtagttat tattttttgg ctcacttgcg
     2701 agaattggct aagacgacca tggatgggac gacggctttg ggcttggtca aggtggcaga
     2761 ggagattggt tttgagacgc gagccattaa ggcggatatg acgctttttg acttgccgga
     2821 tttgactttt ccttttgttg cccatgtgct taaggaaggg aaattgctcc actactatgt
     2881 ggtgactggg caggataagg atagcattca tattgccgat ccagatcccg gggtgaagtt
     2941 gactaaactg ccacgtgagc gttttgagga agaatggaca ggagtgactc tttttatggc
     3001 acctagtcca gactataagc ctcataagga acaaaaaaat ggtctgctct cttttatccc
     3061 tatattagtg aagcagcgtg gcttgattgc caatatcgtt ttggcaacac tcttggtaac
     3121 cgtgattaac attgtgggtt cttattatct gcagtctatc attgatacct atgtgccaga
     3181 tcagatgcgt tcgacactag ggattatttc tattgggcta gtcatcgtct acatcctcca
     3241 gcaaatcttg tcttacgctc aggagtatct cttgcttgtt ttggggcaac gcttgtcgat
     3301 tgacgtgatt ttgtcctata tcaagcatgt ttttcacctc cctatgtcct tctttgcgac
     3361 acgcaggaca ggggagatcg tgtctcgttt tacagatgct aacagtatca tcgatgcgct
     3421 ggcttcgacc atcctttcga ttttcctaga tgtgtcaacg gttgtcatta tttctcttgt
     3481 tctattttca caaaatacca atctcttttt catgacttta ttggcgcttc ctatctacac
     3541 agtgattatc tttgccttta tgaagccgtt tgaaaagatg aatcgggata ccatggaagc
     3601 caatgcggtt ctgtcttctt ctatcattga ggacatcaac ggtattgaga ctatcaagtc
     3661 cttgaccagt gaaagtcagc gttaccaaaa aattgacaag gaatttgtgg attatctgaa
     3721 gaaatccttt acctatagtc gagcagagag tcagcaaaag gctctgaaaa aggttgccca
     3781 tctcttgctt aatgtcggca ttctctggat gggggctgtt ctggtcatgg atggcaagat
     3841 gagtttgggg cagttgatta cctataatac cttgctggtt tactttacca atcctttgga
     3901 aaatatcatc aatctgcaaa ccaagcttca gacagcgcag gttgccaata accgtctaaa
     3961 tgaagtgtat ctagtagctt ctgagtttga ggagaagaaa acagttgagg atttgagctt
     4021 gatgaaggga gatatgacct tcaagcaggt tcattacaag tatggctatg gtcgagacgt
     4081 cttgtcggat atcaatttaa ccgttcccca agggtctaag gtggcttttg tggggatttc
     4141 agggtcaggt aagacgactt tggccaagat gatggttaat ttttacgacc caagtcaagg
     4201 ggagattagt ctgggtggtg tcaatctcaa tcagattgat aaaaaagccc tgcgccagta
     4261 catcaactat ctgcctcaac agccctatgt ctttaacgga acgattttgg agaatcttct
     4321 tttgggagcc aaggagggga cgacacagga agatatctta cgggcggtcg aattggcaga
     4381 gattcgagag gatatcgagc gcatgccact gaattatcag acagaattga cttcggatgg
     4441 ggcagggatt tcaggtggtc aacgtcagag aatcgctttg gcgcgtgctc tcttgacaga
     4501 tgcgccggtc ttgattttgg atgaggcgac tagcagtttg gatattttga cagagaagcg
     4561 gattgtcgat aatctcattg ctttggacaa gaccttgatt ttcattgctc accgcttgac
     4621 tattgctgag cggacagaga aggtggttgt cttggatcag ggcaagattg tcgaagaagg
     4681 aaagcatgct gatttgcttg cacagggagg cttttacgcc catttggtca atagctagaa
     4741 agaggagagg atgaaaccag aatttttaga aagtgcggag ttttataatc gtcgttacca
     4801 taatttttcc agtagtgtga ttgtacccat ggcccttctg ctcgtgtttt tacttggctt
     4861 tgcaactgtt gcagagaagg agatgagttt gtccactaga gctactgtcg aacccagtcg
     4921 tatccttgca aatatccagt caactagcaa caatcgtatt cttgtcaatc atttggaaga
     4981 aaataagctg gttaagaagg gggatctttt ggttcaatac caagaagggg cagagggtgt
     5041 ccaagcggag tcctatgcca gtcagttgga catgctaaag gatcaaaaaa agcaattgga
     5101 gtatctgcaa aagagcctgc aagaagggga gaaccacttt ccagaggagg ataagtttgg
     5161 ctaccaagcc acctttcgcg actacatcag tcaagcaggc agtcttaggg ctagtacatc
     5221 gcaacaaaat gagaccatcg cgtcccagaa tgcagcagct agccaaaccc aagccgaaat
     5281 cggcaacctc atcagtcaaa cagaggctaa aattcgcgat taccagacag ctaagtcagc
     5341 tattgaaaca ggtacttcct tggccggtca gaatctagcc tactctcttt accagtccta
     5401 caagtctcag ggcgaggaaa atccccaaac taaggttcag gcagttgcac aggttgaagc
     5461 acagatttct cagttagaat ctagtcttgc tacttaccgt gtccagtatg caggttcagg
     5521 tacccagcaa gcctatgcgt cagggttaag cagtcaattg gaatccctta aatcccaaca
     5581 cttggcaaag gttggtcagg aattgaccct tctagcccag aaaatcttgg aggcagagtc
     5641 aggtaagaag gtacagggaa atcttttaga caaggggaaa attacggcaa gtgaggatgg
     5701 ggtgcttcat cttaatcctg agaccagtga ttctagcatg gttgcagaag gtgccctact
     5761 agcccaactt tatccatctt tggaaagaga agggaaagcc aaactcacag cctatctaag
     5821 ttcaaaagat gtagcaagaa tcaaggtcgg tgattctgtt cgctatacta cgactcatga
     5881 tgccgggaat caactttttc tagattctac tattacaagt attgatgcga cagctactaa
     5941 gactgagaaa gggaatttct ttaaaatcga ggcggagact aatctaactt cggagcaggc
     6001 tgaaaaactt aggtacgggg tggaaggccg tctacagatg attacgggca agaaaagtta
     6061 tctacgttat tatttggatc aatttttgaa caaagagtaa tgttcgtgtt tttagagtta
     6121 aataattttt aaactgtgag aaagattctt cttgcagttt tttctttaca atttttgaaa
     6181 aacatctgct atttattcgg ttaaattctt gtgttttttg gttttttgtg gtaaaatgtg
     6241 ctcaagtaat acgaaaggcg aactttaaaa tgtcaaaaca attgatctat tcgggaaaag
     6301 ctaaagatat ctatacaact gaggatgaaa atcttattat ttcaacttac aaggaccagg
     6361 cgactgcttt caatggtgtc aagaaggagc agattgcagg taagggagtc ttgaataatc
     6421 agatttcatc ttttattttt gagaaattaa atgcggctgg tgtggcgact cactttgtgg
     6481 agaaactttc agacacggaa caactcaata aaaaggttaa gattattcct ttggaagtcg
     6541 tgctccgcaa ctatactgct ggttcctttt caaaacgttt tggtgtggat gagggaatcg
     6601 ccttggagac tccgattgtc gaattttact acaaaaatga tgatttggat gatccattta
     6661 tcaatgatga gcatgtgaaa ttcctacaga ttgcggatga ccagcagatt gcctacttga
     6721 aggaagaaac gcgtcgtatc aatgaactat tgaaagtctg gtttgctgag attgggctta
     6781 aattgattga ctttaagcta gagttcggtt ttgacaagga tggcaagatt atcttggcag
     6841 acgaattttc accagataac tgccgcttgt gggatgctga tggcaaccac atggataagg
     6901 atgttttccg tagaggattg ggagaactaa ccgacgttta tgagattgtt tgggaaaagt
     6961 tgcagggttt aaaataacaa cctcaaggct gtttgggaat attgcaagag ctgaaataaa
     7021 ggaataagaa ttgatggata aacgtatttt tgttgaaaaa aaggctgatt ttcaggtcaa
     7081 gtcagagagt ttggttagag agctccagca caacttggga ctgtcaagct tgaaaagtat
     7141 tcgtattgtg caagtatatg atgtatttga cttggttgag gacttgtttg cacctgcaga
     7201 gaagcacatt ttctctgagc aggtaaccga ccatgtttta gatgaagtat ctgtgcaggc
     7261 ggatcttgct aactatgctt tctttgccat tgaaagtcta ccagggcagt ttgaccagcg
     7321 tgcagcttcg tcacaggaag ccttgctttt gttgggaagt tcgagtgacg tgacagtcaa
     7381 cacagcccaa ctttacttgg tgaataaaga tattgatgcg actgagttgg aagctgtcaa
     7441 aaactacctg ctcaatccag ttgattctcg tttcaaggat atcacgatag ggattgccaa
     7501 gcaggagttt tcagagtcag acaagaccat tccaaaattg cctttctttg aaagctatac
     7561 agcagaagac tttgctcgct acaaggccga acaagggatg gccatggaag tggatgattt
     7621 gctctttatc caagactact ttaagtcaat cgggcgcgtg ccaactgaga ctgaactcaa
     7681 ggttttggac acttactggt ctgaccactg ccgtcatacg acttttgaga cagagttgaa
     7741 acacatcgac ttttcagctt ctaaatttca aaagcaattg cagtcaacct atgacaagta
     7801 tattgccatg cgcgaggaat taggtcggtc tgaaaaacca caaaccttga tggatatggc
     7861 gactattttc ggtcgttatg agcgtgctaa tggacgattg gatgatatgg aagtctctga
     7921 cgaaatcaat gcctgctcag ttgaaattga agtggacgtt gatggtgtca aggaaccttg
     7981 gctcctcatg tttaaaaacg aaacccacaa ccatccaaca gaaattgagc catttggtgg
     8041 agcggctacc tgtatcggtg gagctattcg tgatccgttg tcaggccgtt cctatgttta
     8101 ccaagccatg cgtatttcag gtgctggtga tattacagca ccgatttcgg aaactcgtgc
     8161 tgggaaattg ccacaacaag tcatttctaa aacagcaact catggttatt cttcatatgg
     8221 taaccagatt gggcttgcca caacctacgt tcgtgaatac ttccacccag gctttgtagc
     8281 taaacgtatg gaacttggtg ccgttgttgg tgcggctccc aagggcaatg ttgtccgtga
     8341 aaaacctgaa gcaggtgatg tgatcatcct tctcggaggt aaaacaggtc gtgatggtgt
     8401 cggtggtgcg acgggctctt ctaaggttca aacagttgag tctgtagaga ctgctggtgc
     8461 tgaggttcaa aaaggaaatg ccatcgaaga acgcaagatt cagcgcctct tccgtaatgg
     8521 caatgtcact cgtctgatca agaagtccaa tgactttggg gcaggcggtg tctgtgtggc
     8581 tatcggtgaa ttggcagacg gtcttgaaat cgacctcaac aaggtgcctc ttaaatacca
     8641 gggcttgaat ggtacagaaa ttgccatctc tgaatcacaa gaacggatgg cggtcgtggt
     8701 tcgtcctgaa gatgtggata ccttcgttgc cgaatgtaac aaagaaaata ttgatgctgt
     8761 tgtggtggcg acagtaactg aaaaaccaaa tcttgtcatg cactggaatg gtgagacaat
     8821 cgttgacttg gagcgtcgtt tccttgacac caatggtgtg cgcgtggttg tcgatgccaa
     8881 agttgtggac aaggatgtca aactcccaga agagcgtcaa acatctgctg aaacactgga
     8941 atcagatacc cttacggttc tatctgacct caaccatgca agtcaaaaag gattacagac
     9001 tatctttgac tgctctgttg gacgctcaac ggttaatcac ccacttggtg gtcgttacca
     9061 actcacacca actgaggcat ctgtgcagaa attgccagtt caacacggtg tgactcatac
     9121 tgcgtcggtc attgctcaag gtttcaaccc atatgtagct gaatggtctc cataccacgg
     9181 tgctgcttat gcggttatcg aagcaactgc tcgtttggtg gctgctggtg ccaactggtc
     9241 taaggctcgt ttctcttacc aagaatattt cgagcggatg gacaagcaag cagagcgttt
     9301 tggtcagcca gtagccgccc ttctaggctc tattgaagca caaattcagc ttggcttgcc
     9361 atctatcggt ggtaaggact ccatgtctgg tacctttgaa gaattgaccg ttccgccaac
     9421 cttggttgcc tttggggtga cgacggcaga tagccgtaag gtgctctctc cagaatttaa
     9481 agctgttggg gaaaatatct actacatccc aggtcaagcc ctctctgcag agattgattt
     9541 tgacttgatt aagaaaaatt ttgctcagtt tgaagcaagc caagctgacc ataaagtgac
     9601 atctgcatca gctgtcaaat acggtggtgt agttgaaagt ttggctcttg ctacctttgg
     9661 aaactatatt ggtgcagagg tgaccttgcc tgaacttaaa acagctttga cagctcaatt
     9721 aggcggcttt gtcttcacat ctcctgaaga aattgctgga gtagagaaga ttggacaaac
     9781 gaaagcagac tttacactga ctgtcaacgg tgtgaagcta gatggacaca agcttgacag
     9841 tgcatttcaa gggacattgg aagaagttta cccaacagaa tttacccaag cgaaagaact
     9901 agaagaagta ccagctgtgg tatcagatgt tgtgattaaa gccaaagaaa aggttgaaaa
     9961 acctgtggtt tacatcccag tctttccagg aaccaactca gaatatgatt cagctaaggc
    10021 cttcgaaaaa gaaggtgcag aggtcaattt ggtgccattc gtgaccttga atgaagaagc
    10081 tattgtcaag tcagttgaaa ctatggttga caatatcgac aagactaata ttctcttctt
    10141 tgccggtgga ttctcggctg cggatgaacc agatggttca gctaagttta tcgtcaatat
    10201 cctgcttaat gaaaaagtgc gtgtggctat tgatagcttt atcgcccgtg gtggcttgat
    10261 tatcggtatt tgtaatggat tccaagcctt agtcaaatcg ggtctcctac catacggaaa
    10321 ctttgaagat gctaacagta ctagtccaac cctcttctac aatgatgcca accaacacgt
    10381 ggccaagatg gtggaaactc gtattgccaa taccaactca ccatggttgg ctggtgtgca
    10441 agtgggcgat atccacgcta ttcctgtttc gcacggtgaa gggaagtttg tcgtgacggc
    10501 tgaggaattt gcagagctcc gtgacaatgg acaaattttc agccaatacg ttgactttaa
    10561 cggtaaacca agtatggatt ctaagtacaa tccgaatggt tctgtccatg ccatcgaagg
    10621 aattaccagc aagaatggtc aaatcatcgg taagatgggc cactcagaac gttatgagga
    10681 tggtcttttc caaaatatcc caggcaataa agaccaacac ctgttcgcat cagcggttaa
    10741 acatttcact ggaaaataag acttacagat tttctaatag atagtatcag taatgtaaaa
    10801 gtcatgtaaa tctagctctt gatgattaca aatgaaaatt aggtataaaa aatgacatac
    10861 gaagtaaaat ctcttaatga agaatgtggt gttttcggta tttggggaca tccagatgct
    10921 gctaagttga cctattttgg actccacagt cttcaacacc gtggtcagga gggggcagga
    10981 atcctctcca atgatcaagg acaactgaag cgccatcgtg acatggggct tttatcagaa
    11041 gttttcagaa atccagccaa tttggataaa ttgacaggag ctggtgcgat tgggcatgtg
    11101 cgttatgcga ctgctggcga agcttctgtt gataacatcc aacccttcct cttccgtttt
    11161 cacgatatgc agtttggttt ggctcataat ggaaatctga ccaatgcagc ctctctcaag
    11221 aaagaactgg aacaaagagg agcaattttc agcgcgactt cggactctga aatcttggct
    11281 cacctcattc gtcgcagtca taatcctagc ctgatgggca aaatcaagga agcgctcagt
    11341 cttgtcaaag gtggttttgc ctatatcttg ctgtttgagg acaagttgat tgcggctctt
    11401 gaccctaatg gctttcgtcc gctttctatc gggaaaatgg ccaacggagc ggtggttgtt
    11461 tcctctgaaa cctgtgcttt tgaggtcatt ggtgccgagt ggatttgtga tttgaagcca
    11521 ggtgagattg tgatcattga tgacgagggc attcagtatg acagctatac agatgatacc
    11581 cagttggcga tttgttctat ggagtatatc tactttgccc gccctgattc taatatccac
    11641 ggtgtcaatg tccatacggc acgtaagaga atgggagcgc aattggcgcg agaatttaag
    11701 catgaggcag atattgtagt tggtgtgccc aattcttccc taagcgcggc tatgggattt
    11761 gcggaagaat caggcttacc aaatgaaatg ggtctgatca aaaaccaata cacccagcga
    11821 acttttatcc aaccgactca agaattgcgg gagcaaggag tgcggatgaa actgtctgct
    11881 gtttcgggtg ttgtcaaagg caaacgtgtg gtcatggtgg atgattccat tgtacgtgga
    11941 acaacctctc gtcgtatcgt tcagctcttg aaagaagcgg gtgcgactga ggttcacgtt
    12001 gccattggaa gtcctgcact agcgtatcca tgtttctacg ggattgatat ccagacccgt
    12061 caggagctga ttgcagccaa tcatacggtc gaagaaactc gccaaatcat tggtgcggac
    12121 agtctgactt atctttcaat tgatggcttg attgagtcga ttggtatcga aacagatgcg
    12181 ccgaacggtg gtctctgtgt cgcttacttt gacggtgact acccaacgcc tctctatgac
    12241 tacgaagaag actatcgtag aagtttggaa gaaaagacca gtttttacaa gtaggcgaca
    12301 gattctccat taaagaaaag gaaaaaacaa atgacaaata aaaatgcata tgcctcacgt
    12361 ctcactactg actaaaggct taagcattta gtcagtagac gctttgtcct ataggatcaa
    12421 agctagagcc ctgactagta tttttagata aaaagatggt ttatctaaaa atacgtcgca
    12481 gtctttctca aaaaaagaaa aggaaaaata aaatggcaaa taaaaatgcg tacgctcaat
    12541 ctggtgtgga tgttgaagcg ggttatgaag ttgttgaacg gattaaaaag cacgtggctc
    12601 gtacggagcg tgcaggtgtc atgggagctc ttggtggctt tggtggtatg tttgaccttt
    12661 ccaagactgg ggttaaagaa cccgtcttga tttcagggac tgacggtgtc ggaaccaagc
    12721 tcatgttggc tatcaagtac gacaagcacg ataccatcgg gcaggactgt gtggccatgt
    12781 gtgtcaacga catcattgct gcaggtgcgg aacccctcta ttttctcgac tacgtagcga
    12841 cagggaagaa tgaaccagct aagctagaac aagtggttgc tggtgtggca gaaggttgtg
    12901 tgcaggctgg tgctgccctc atcgctgggg aaacggctga aatgccgggc atgtacggcg
    12961 aagacgacta tgacttggct ggttttgcgg tcggtgtggc tgaaaaatct caaatcattg
    13021 acggttcaaa ggtggtagag ggagatgttc ttctcggact tgcttcaagt gggattcact
    13081 caaatggtta ctctttggtt cgtcgtgtct ttgcggatta cacaggtgag gaagtcctac
    13141 cagaattgga aggcaagaaa cttaaggaag ttctacttga gccgactcgt atctatgtca
    13201 aggctgtctt gccgctcatc aaagaagagt tggtcaacgg cattgcccac atcacaggtg
    13261 gtggctttat cgaaaatgtc cctcgtatgt ttgcagatga cctagctgct gaaattgatg
    13321 aaagcaaagt tccagtgctt ccaattttca aagcccttga aaaatatggt cagattaaac
    13381 acgaagaaat gtttgaaatc ttcaatatgg gtgtgggact tatgttggcg gtcagccctg
    13441 aaaatgtaga gcgtgtaaaa gaattgttgg atgaagcagt ctatgaaatt ggtcgcatcg
    13501 tcaagaaaga aaacgaaagt gtcattatca aatgaaaaaa atagcggttt ttgcctctgg
    13561 taatggctca aattttcagg tgattgccga agaatttcca gtggagtttg tcttttcaga
    13621 ccatcgtgat gcctatgtgc ttgagcgtgc aaagcagctc ggcgttctgt cctatgcttt
    13681 tgaactcaag gagtttgaga gcaagacaga ctacgaagca gcccttgtcg aactcttgga
    13741 agaacaccag attgacttgg tttgcctagc aggctacatg aaaatcgttg gaccaacctt
    13801 attgtcggct tatgaaggtc ggattgtcaa cattcatcca gcctacttgc cagaatttcc
    13861 aggagctcat gggattgagg atgcttggaa tgctggcgtg ggtcagtctg gtgtgaccat
    13921 tcactgggtg gattcgggtg tggatacagg ccaggtcatc aaacaggttc gtgtgccacg
    13981 actagctgat gataccattg acagatttga agctcgcatc catgaagcag agtacaggtt
    14041 gtatccggaa gtagtgaagg ctctatttac agattgactt tttgatgatt catatgatat
    14101 ctttgatttt aaattggagt cagtgtttgt tgaagacggc ttcaaacgga ggtatttgta
    14161 atgttagaat ctaaaaaaac aactcgatat gtattttatg tctatctgat gttattaact
    14221 tggggaatct tatttaagtt tgaaacaaat cctgaattta tagcattttt cttagctcca
    14281 aggtatatca attggattcc attttcagaa ccactaatag tcgatggaaa aattgttttt
    14341 gctgaaatgt tatttaatct gatttccttt attccattag gtgtttgttt ccctttgata
    14401 aaaactaatt tatctagttt aagaatagtc gggacaggtt tcttgattag tttattgttt
    14461 gagtgcttac agtatatttt agcaataggt ataacagata taacggattt gactttaaat
    14521 acgctaggtg tctgtgtagg cttactgatt tatcaaattt ttataagagt gttcaaatca
    14581 cagactagaa aatggatcaa tatcttaggt atgcttagcc ttggttttgc ttatcttgtt
    14641 ttactgttac tgcatttaat tggtgtttaa ctaatgatta aaaaggagaa tataatgact
    14701 aaacgcgtct taatcagcgt ctcagacaaa gcgggcattg ttgaatttgc ccaagaactc
    14761 aaaaaacttg gttgggagat tatctcaaca ggtggaacta aggttgccct tgataatgct
    14821 ggggtggata ccattgctat cgatgatgtt actggtttcc cagaaatgat ggacggtcgt
    14881 gtgaagaccc tccacccaaa tatccacgga gggcttctcg ctcgtcgtga cttggatagc
    14941 cacttggaag cggctaagga caacaagatt gagctcattg accttgtggt ggtcaacctt
    15001 tacccattta aggaaactat ccttaaacca gatgtgactt atgctgatgc agttgaaaat
    15061 atcgatattg gtgggccgtc tatgcttcgt tcagcagcga aaaatcatgc cagtgttaca
    15121 gttgtggtag atcctgctga ctacgctgtg gttttggacg aattggcagc aaacggcgaa
    15181 acctcttatg aaactcgcca acgtttagca gccaaagtat ttcgtcacac agcggcttat
    15241 gacgccttga ttgcagaata cttcacagct caagtgggtg aaagcaagcc tgaaaaactc
    15301 actttgactt atgacctcaa gcaaccaatg cgttacggtg agaatcctca acaagacgcg
    15361 gacttttacc agaaagcttt gcctacagac tactccattg cttcagccaa acagctcaac
    15421 gggaaagaat tgtcatttaa taatatccgt gatgcagatg ctgctatccg tatcatccgt
    15481 gacttcaaag atagtccaac cgttgtggct ctcaaacaca tgaatccatg tggaattggt
    15541 caagctgatg acatcgagac tgcttgggac tacgcttatg agtctgaccc agtgtctatc
    15601 tttggtggga ttgtcgtcct caaccgtgag gtggatgctg cgacagctga gaagatgcac
    15661 ggcgttttcc tcgaaatcat cattgcacca agctatacgg atgaagcgct agccattttg
    15721 atcaataaaa agaaaaactt gcgtatcctt gccttgccat ttaatgctca agaggctagc
    15781 gaagtggaag cagaatacac aggtgtagtc ggtggacttc tcgtgcaaaa tcaagacgtg
    15841 gtcaaggaaa gcccagctga ctggcaagtg gtgactaaac gtcagccaac tgagacagaa
    15901 gcgactgctc ttgagttcgc ttggaaggct atcaagtacg tcaaatcaaa tggtattatc
    15961 gtgaccaacg accacatgac acttggtgtt ggtccaggtc aaaccaaccg tgtggcttct
    16021 gttcgccttg ccattgacca agccaaagat cgtctggacg gggcggtcct tgcttcagat
    16081 gccttcttcc catttgcgga taacgtggaa gaaatcgcca aagcaggaat taaggccatc
    16141 atccagcccg gtggctctgt ccgtgaccaa gaatccatcg aagcagcgga taaatacggc
    16201 ttgactatgg tctttacagg tgtgagacat tttagacatt aagaagataa aagggaagaa
    16261 aacagtttct ttcctttttt ggcttaaaat gctaactgaa acaagattaa aacgaacttt
    16321 tttgatataa tgttggtaaa taattcgcaa aagaggttga ggaatgaaac tgcttgttgt
    16381 cggttctggt ggtcgtgagc atgcgattgc taaaaagtta cttgaatcaa aagacgtgga
    16441 aaaagtcttt gtagctcctg ggaatgatgg gatgactctg gatggtttgg aattggtaaa
    16501 tatctctatt tccgaacatt ctaaattgat tgacttcgca aagaccaatg atgttgcttg
    16561 gacctttatc ggtccagatg atgcccttgc tgctggcatc gtggatgatt ttaaccaagc
    16621 tggacttaag gcctttggtc cgactagggc tgcagcggag ctggagtggt ccaaggattt
    16681 cgccaaggaa atcatggtca aatacggcgt tccgacagca atatatggca cattttcaga
    16741 tttcgaggaa gccaaggcct atatcgaaaa gcatggtgcg cctatcgtag tcaaggcgga
    16801 tggcttggca cttgggaagg gtgtcgtcgt tgctgagacg gttgagcaag cggtcgaagc
    16861 cgctcatgag atgcttttgg acaataaatt tggtgactca ggtgcgcgcg tggttattga
    16921 ggaattcctt gaaggcgagg aattttcact ctttgccttt gtcaatggtg ataagttcta
    16981 catcatgcca acggctcagg accacaaacg tgcctatgat ggcgacaaag ggcctaacac
    17041 gggtggtatg ggtgcctatg cgccagttcc acacttacca cagagtgtag ttgatacagc
    17101 ggttgacacc attgtcaagc cagttctaga aggggtgatt aaagaaggtc gtccttatct
    17161 gggagttctt tacgcagggc ttatcctgac agctgatgga ccgaaggtca tcgagttcaa
    17221 cgctcggttc ggagatccag aaactcagct tatcttgcct cgcttaacct ctgactttgc
    17281 tcaaaatatc acagatatcc tggatagcaa ggagccaaat atcacgtgga cggacaaggg
    17341 tgtgactctg ggtgtggttg tcgcatccaa gggctacccg ctagattatt caaagggtgt
    17401 tgagttgcca gtcaaaaccg atggcgacat cattacctac tatgcagggg ctaagtttgc
    17461 ggaaaatagc agagcactgc tctcaaacgg cggacgagtt tatatgctcg ttaccacagc
    17521 agataccgtc aaagaagccc aagccagcat ctaccaagaa ctatcccaac aaaaaataga
    17581 aggactcttc taccgaacag atatcggaag caaggcaatt aagtaaagat ataagaataa
    17641 cgcgccgtag tcgccaaaca cgataatggt cgtcgtggtg aaaagaccag aacagtgaat
    17701 gttctggtca gggggaaact tggagaccgt aggctcaaag tttaggaatg aaaccgaagg
    17761 tttgcttccg cctccatcac ctaagaccat tatcaaaaag aaaaataaaa attcacaaaa
    17821 tacgttaatg gtcgtatggt ttgcgagcgt tagcgagcta atatagaata atcaccgccg
    17881 ttgtgaaaga acgattggat gacaatccaa tcgttcaggg aaattggaag accttgggtt
    17941 tccaatttag gcatgagaca cctttggtgg ttgctgccgt ccctcacaag ctaaggtgat
    18001 tgttgaaaaa gaggaaaaag gagaagaaat gaaaccagta atttccatca tcatgggctc
    18061 aaaatccgac tgggcaacca tgcaaaaaac aacagaagtc ctagaccgct tcggtgtagc
    18121 ctacgaaaag aaagttgttt ccgcacaccg tacaccagac ctcatgttca aacatgcaga
    18181 agaagcccgt agtcgtggca tcaagatcat catcgcaggt gctggtggcg cagcgcattt
    18241 gccaggcatg gtagctgcca aaacaaccct tccagtcatt ggtgtgccag tcaagtctcg
    18301 tgctcttagt ggagtggatt cactctattc tatcgttcag atgccgggtg gggtgcctgt
    18361 tgcgaccatg gctatcggtg aagctggagc gactaacgca gctctctttg ccctccgtct
    18421 cctctctgta gaagataagt ccattgcgga tgcacttgcc aactttgctg aagaacaagg
    18481 aaaaatcgca gaggagtcgt caaatgagct catctaaaac aatcggaatt atcggtggcg
    18541 gtcaactggg tcagatgatg gccatttctg ctatctacat gggccacaag gttatcgcgc
    18601 tggatcctgc ggcggattgc ccggcctctc gcgtggcgga aatcattgtg gcaccttata
    18661 acgatgtgga cgccctccgt cagttggcag accgttgcga tgtcctcact tacgagtttg
    18721 aaaatgtcga cgctgacggt ttggatgccg ttatcaagga tggacaactc cctcaaggaa
    18781 cagatctgct ccgcatttcg caaaatcgta tttttgaaaa ggactttttg tcaaacaagg
    18841 ctcaagtcac tgtggcaccc tacaaggtcg tgacttctag cctagacttg gcagatatcg
    18901 acttgtcgaa aaactatgtc ctcaagactg cgactggtgg ctacgatggt catggacaaa
    18961 aggttattcg ttcagaagca gacttggaag cagcctatgc gctagcagac tcagcagact
    19021 gcgtcttgga agaatttgtc aactttgacc ttgagatttc tgtcatcgtg tcaggaaatg
    19081 gcaaggaggt gacgtttttc ccagttcagg aaaatatcca ccgcaacaat atcctgtcta
    19141 agaccatcgt accagcccgc atttctgaaa gtctagtaga caaggctaaa gctatggcag
    19201 tgcgaatcgc agaacaactc aacttgtctg gaactctctg tgtggaaatg tttgcgactg
    19261 atgatgacgt tattgtcaat gaaatcgccc cacgaccaca taactctggg cactattcta
    19321 ttgaagcctg tgatttctct cagtttgaca cccatattct cggtgttctc ggagcaccat
    19381 taccagtcat caaactccat gcgccagccg ttatgcttaa tgtcctcggt cagcatgtcg
    19441 aggctgctga gcaatatgtg acagaaaatt caagcgccca cctccacatg tatggtaaaa
    19501 tagaagcgaa gcacaaccgc aagatgggac atgtgacctt gtttagtgat gtaccggata
    19561 gtgtggatga gcttggggaa gggattgatt tttaggacaa gtctatgata caaattatcg
    19621 ttaatacatt tattgaaaag gataagactg gagcagttgt tgaagtgttg tatgccagtg
    19681 ctgaccaaga taaggtacaa gctaaatatg aagaactagc tgcataatac cccgaaaatt
    19741 atttagctat ctatgatgta ccgctggata cggatttgaa tacactagat cattacccgt
    19801 ctgtgtttat tgaaaaagag gagtttgagt agaaatcttg gtttacctag atagcttatt
    19861 cccaacagct taagaagaaa ggaaaaatta acacatgatc aaccgttact ctcgccctga
    19921 gatggcgaat atttggagtg aagaaaataa ataccgtgct tggcttgagg tggaaatcct
    19981 ctctgacgag gcatgggctg agttggggga aatccctaag gaagatgtgg ctttgattcg
    20041 caagaaggcg gactttgaca tcgaccgtat tttggaaatt gagcaggaga cgcgccacga
    20101 tgtggtggct ttcacgcgtg cggtttctga gactcttggt gaagagcgca agtgggttca
    20161 ctatgggtta acttctaccg acgtggtgga tactgcttat ggttacctct acaagcaggc
    20221 caacgacatc atccgtcgtg accttgaaaa cttcactaat atcatcgctg acaaggccaa
    20281 ggagcacaag ttcaccatca tgatggggcg tactcatggt gtgcacgctg agccgacaac
    20341 ctttggtctt aaattggcaa cttggtacag cgaaatgaaa cgcaatatcg agcgtttcga
    20401 gcatgcagct gctggtgtag aagctggtaa gatttctggt gcggttggga actttgccaa
    20461 tatcccacca tttgtagagg agtatgtctg cgataaactt ggcatccgtg cccaagaaat
    20521 ctctacacaa gtccttcctc gtgaccttca cgctgagtac tttgcggttc ttgccagcat
    20581 tgcgacttca atcgaacgta tggcgactga gattcgtggt ctacaaaaat ctgagcaacg
    20641 cgaagtagaa gagttctttg ctaaagggca aaaagggtct tcagcaatgc ctcacaaacg
    20701 caacccaatc ggttctgaaa atatgactgg tctggcgcgt gtcattcgtg gtcacatgat
    20761 tacggcttat gaaaacgtcg ctctctggca cgaacgcgat atttctcact catcagctga
    20821 gcgtatcatc acaccagata cgaccatttt gattgactac atgctcaacc gttttggaaa
    20881 tatcgtcaag aacttgacag tcttcccaga aaatatgatc cgaaacatga actcgacttt
    20941 tggtcttatc tttagccaac gggctatgtt gacattgatt gaaaaaggca tgacccgtga
    21001 gcaagcctat gacttggtgc aaccaaaaac agcctactct tgggacaacc aagtagactt
    21061 taaaccactt cttgaggcag attcagaagt aacatcacgt ctcactcaag aagaaatcga
    21121 tgaaatcttc aacccagttt attacaccaa acgagtggat gatatctttg aacgtcttgg
    21181 actaggtgat taattaaaaa ataaacagcg agcttcaatc tcgctgttta ttttttatcg
    21241 aaaagactta gtcttctttt cttttagtga gtccataggc tgctagtgtg gacatgagtc
    21301 ctgcgactac tagtcctgca gaatcgtgag ttcctgtttc aggaagtttt ttctctgtta
    21361 ccacaggagc tggatcttga ggaagagctt tgctttcctc agcaggagca gttgatggag
    21421 ctggttggct tgggatttct agttttggtt tttcttcagc aatagcggct tgtccgtttt
    21481 catcgcctac atgtgttacc atagttccga cttcgactat ttgagtaacg gcttcctgtg
    21541 ctacgacact atttacaagt gttttcactt ccttaccatc ggcagaagtg ctcacagagt
    21601 agaagttgct acgatgtcca ttgacgccct tagtaatgac ttgtgttttt cctttgagta
    21661 agagtggatt ttcacgagtc actgtggtaa atggaatttc ttctttttgg atatccagtc
    21721 taggttttac ctcagtagtt ggtgcaagac cactttcatc acccttgtga gttacaggag
    21781 cgccaacttc aaccacttgg tttataactt ctttggttac ctggctatca aggactgttt
    21841 ctgttgtttt tccattttca gtgagtacag agatgtaatg agttcgttca cctttgactc
    21901 ctgctgtgat aatattttct tgaccagctg ggaggttagg attttctttc ttgataactt
    21961 caaatggaat ttcttcagtt cttgtgatga gttctggtct ggtttcaaca ttggcagcca
    22021 cttcattttc atctaggctt cctgaatgag ttgcagctgg tttgaggcct tgaagagcgg
    22081 cttttaggtt ggctacaagt gtgtcaagct cagcttgttt attacggttg aggttgtaat
    22141 ttagagctgt tttagctgcg tcaagggcct caagactttc tttactatat ccttctaagt
    22201 ttgtaggaat tttagctaat tcttcgcgga gagcattata attagcacgg aagtagtctt
    22261 tgttgtggtc tgcaaaggca gtcatgagtt caaagatttc ctcttccttg tattcagcgc
    22321 ttggtctatc tgcccagatt gaaagcatac ttccgactgt tggaagatct acttcaggat
    22381 atttggtaga agctagttga ttgaatggaa ctttaccaga attttcaact gcttttgaaa
    22441 gagggtaagc ttcctcttgt ttgtgattgc ctataacata ataccagtca ccgttggtat
    22501 tcaagaattt atagcctttg cttgctaggt attgaggtga tgcgaggtta tatccccacc
    22561 agcctttaga ccagtaagaa atcaagacat ctttgtcaaa ctgaacatcg tccttgtctt
    22621 catagtagaa gccatcgttg aaggccattg gttgaagccc tctttctttg gccatagctg
    22681 cgagggtgtt ggcatattcg gcaaatttgc catagagttg ataccacttg aggtagtacc
    22741 agccttgggc actagtcgca tcgttggcgt attcgtcagt accaaagttg aaaatctttg
    22801 ttttacctgc aaagaagtcc atgtatttac cgatgagggc ttttacaaag tccatcgctt
    22861 cttcgttttt caagtccata gttgtttttg aaactttatc aaagtgggct tgaggatttt
    22921 taatacctaa tttttccatg gcaaccagca tagcatccat gtgacctgga ctgttaatag
    22981 ctgggatgag accgatgtcc ttagatttag cgtattcaat tagctctgtc acttctgcct
    23041 gtgttagtgc agtaccgttt ggatcgtcgt agtaagcttt agttccttcg ataatagctt
    23101 ttttaacgtc atcactagca taggtttttc cgttggcagt aatggtcata tcattgagta
    23161 gaaagcgaag tccgtcattt cctagaagga gatggacatc agaatatccg agctcactgg
    23221 ccttgtctac gatgcgtttg agctggttca gagtaaagta tttgcgtcca gcatcgattg
    23281 agattacctt gtttttggca agtttttcaa cctcacgttt agcttcttct tctttttgag
    23341 cttcaggcgt gagggtcaag ttgttgacag tttcttgaag tttagcaatg gcttgatcaa
    23401 tcgtatcttg ttgggcacgg ctaaggttgc tatcgagaga gcgaatagct ttttcagctt
    23461 cttttacggc cgcgacgctt tctgcagtat aacggttcag gtcttttggt acctcgttaa
    23521 gtgcttgctc tgcagattca taatcagctg cgaagtattc agcgttggca tttgcaaaat
    23581 gacgcatgag tttgaagagg cgtgatggtg aataacgtgc agatggagtg tcagcccaag
    23641 cagctaccat accaccgatg attgggatat cagctccttc tgtttttggt acagaagtga
    23701 ttggtgtgtt tttaatacca ttgagcccct gatcgagatt gtaccagcct tggccatcag
    23761 cgtttcgtcc aagaacgtag taccaagcat cattggtatt aaggatttgg tgaccttttt
    23821 cagctagtag tttagaagaa gcgacatcgt agcctcccca accaccagtc cacatagaaa
    23881 cgatgatgtc tttgtcaaaa ctaccaaagc ttgtgtcgct attgtagtag ataccgtcgt
    23941 taaaggccat tggtttgaga ccgtgcgatt ttacaatacg agcgaggtca ttggcgtagg
    24001 caataaattt ttcatagcct tttacagggt agccttcgtt tggatagtat ttatcagctt
    24061 gaagcacact ccaaccttta gcatctgtcg catcattggc atattcatca agtccgatgt
    24121 tgaagatttc agtctttttc gcgaaataag cagcatactt gtcgataagg gcttttgtaa
    24181 aagcgacagc ttgttcgttg tcaagatcga cagtacgggc tgatttcttc ccaaaatagc
    24241 taaagttagg gttttggatt cccaattctt tcatggcatt gagaatcgca tccatgtgtc
    24301 caggactatt tactgtcgga atgagaccga tacctttatc tttggcatag ttaatcagat
    24361 ctgtcatttg actttctgtt aagtgattgc cgtttggatc gttgtaataa tcatttgtac
    24421 ctttttcaat ggcgcgtttg acatcgtcac tggcataggt cttgccgtta gctgtgatgc
    24481 tcatatcgtc caacatgaaa cggagtccat catttccgac taataggtgt aaatcagtgt
    24541 agccataatg tttcgcttta tcgatgattt ccttgagctg ttctggtgag aaatatttac
    24601 gtccagcatc aatagaaaca attttctttt tcgctagttt ttcatttaca gttgcagcac
    24661 gttcctttcc tgcctctgtt tccggtttgt cagcctctgc tttcgcttca tcttttttag
    24721 ctggtttatc cttgtcagtc ttgtctgtat ttgactcttt agaatcaacc tctttcgctt
    24781 cttccttttt agggctagct tcttctgcct ttttattagc agtttctttt tcagcagaag
    24841 ttggagttac cacttctgct ttatcactag gagttgaact aacttcctct tgtggttttt
    24901 cttctgtttt tggaagacta gctaccttat cagtagctgg agtttctgtt tctacagttt
    24961 ttggagcttc tggttgaagc actgctttag gtgtttcctc agtccgattt tcggatgatt
    25021 gaggggaatc agaaaccgta tggatggtcg gttggttttc tgtagtagta ggagtaactc
    25081 catcggctgc aacagtctgt gcttggaagg caaatccaat tagaacagaa gctgctccta
    25141 cagcgtattt acgaatagaa aaacgctgtt gtttttcatg tttcattgca aaacctcctg
    25201 attgcattgt tatattgata gcgattatat aaatcaacgc ccttatttta tttcttatat
    25261 taacgagagt caagaggaga tgacaaaaaa ctataataag tataaaaaaa tataaaattt
    25321 aaacttaaga tttcagattg gtcggaaaaa atgcatatat atatctagta taatttttgg
    25381 ttctatttct ataaaatatt ccacaaatta tagaatcttc caaaaatagg taagcgctac
    25441 ctttttggtg tggtataata agcatagaaa aagcccaagc gattagctca ggttttcttc
    25501 ttagtgatca cggtcacatg agataaattt aatcttgtag taatcagatc gtttgtaagt
    25561 ttcactgtat tctaaaactt ggccagttga ttcgagtttg gtgattttag tttgtaggac
    25621 agtagggaat tgttcatcga ctccgaggac tgaagccgca tgttctggag ttggaaagac
    25681 tatttcgttg atttcttcaa agtgttcatc attcatgtga atgtggtagt ctaacttgaa
    25741 acgattatag atagaactat agtattcaag gtttggataa tttgcgttga tatattgttc
    25801 tgggatgtag gatgtatggt agatataaac gacaccgttt gattcgcgga tacgttcaat
    25861 cttgtagtag aattgatcgc cgcgtagacc caatttttcc aagtaaacaa gcttgtttcc
    25921 gcgttcaatt gaaagaacag ttaccttatc atctttagca ttgaagagct caatatctga
    25981 aaactctaca agcttgtgtt tgcgtgcacg tgaaacgaag gttccttttc cttgttggcg
    26041 gacaatatag ccatctttgg caaggtcgtt taaggcgcga acaactgtga tagagctgac
    26101 atcgtacatt gaaatgagtt ctgcttcagt gtaaaattta tctccactgc taaactgccc
    26161 agagatgatt ttatttttta attcgtcttt tatgtattga tatttgggaa ttgccatatt
    26221 tttacctcta ttttccttct ccatagaaaa ttttaccata aaagcgaaaa aaatagtagt
    26281 cttttgaata aaaaattaga ataatagttt gaaaaattaa gcgatatagg gattgctcat
    26341 attttatcaa tgcattctat acaaaattat tttaggtcct atattccgaa tttaaagagc
    26401 gtttgaaatg ggtctaaaaa tgtttgaaac taattgaatg tgtgtataat agtaaaaatg
    26461 cagtaaatat cccgacaatt tctattgaca attcaaacag attggtttat aattaatata
    26521 acaacaaatg aaagcgcaaa ctttcgcggt cggaaggtag ttttatgaca cgatttgaga
    26581 tacgagatga tttctatctc gatggaaaat catttaagat tttatctggt gccattcatt
    26641 attttaggat tcctccagag gattggtatc attcgctcta taacttgaag gctcttggtt
    26701 ttaatacggt agagacttat gttgcttgga atttacacga gcctcgtgaa ggtgagtttc
    26761 attttgaagg tgatctggat ttagagaaat ttctccaaat agcgcaggat ttgggtctct
    26821 acgcaattgt gcgtccgtct ccatttatct gtgcggaatg ggaattcggt ggcttaccag
    26881 cttggctctt gaccaagaac atgcgaattc gctcatccga cccagcatat atcgaggcag
    26941 ttggtcgcta ctatgatcag ttattgccaa gactggtgcc tcgtttgttg aacaatggtg
    27001 gcaatattct catgatgcag gttgaaaatg agtatggttc ttacggagaa gataaggctt
    27061 acctgagagc gattcgacag ctaatggaag agtgtggcgt aacctgtccc ctctttacat
    27121 cagatggtcc atggcgagct actctgaaag ctggaacctt aattgaagag gacctctttg
    27181 taacaggaaa ctttggttct aaggcacctt acaacttttc gcagatgcag gaattctttg
    27241 atgaacatgg taagaaatgg ccactcatgt gtatggagtt ctgggatggt tggttcaatc
    27301 gctggaaaga accgattatc acacgggatc ctaaggaatt ggcagatgca gttcgagagg
    27361 ttttggaaca aggctctatc aatctttaca tgttccacgg tggtacaaac tttggtttca
    27421 tgaatggttg ctcagctcga ggaactttgg acctgccaca agttacatct tatgattacg
    27481 atgcccttct ggatgaagaa ggaaatccaa ctgctaaata tcttgcagtc aagaagatga
    27541 tggcaacaca tttttcagag tatccgcagt tggaaccact ctacaaagag agtatggagt
    27601 tggatgctat tccactagtt gaaaaagttt ctttgtttga aaccttagat agcttgtcaa
    27661 gtcctgtaga aagtctctat cctcaaaaga tggaggagct gggacaaagt tatggctacc
    27721 tactttatcg aacagaaaca aactgggatg cagaagaaga aagacttcgt atcattgatg
    27781 gtcgagatag ggcccagctg tatgtcgatg gtcagtgggt taaaactcaa tatcagacag
    27841 agattgggga agatattttt tatcaaggta aaaagaaagg gctatctagg ttagatatct
    27901 tgatagaaaa tatggggcgt gtcaactatg ggcataagtt cttagcggat acgcaacgta
    27961 agggaattcg gacaggggtc tgtaaggatc tgcatttctt actaaactgg aaacactatc
    28021 cactcccact agacaatcct gagaaaattg atttttcaaa aggatggact caaggacaac
    28081 cagcctttta cgcttatgac tttacagtcg aagagccaaa agatacttac ctagacttgt
    28141 ctgagtttgg taagggagtt gcctttgtca atgggcagaa tctaggacgt ttttggaacg
    28201 ttggcccaac tctctcactt tatatccctc atagctatct caaggaaggt gccaaccgta
    28261 tcattatctt tgaaacagaa ggtcaatata aagaagagat tcatttaact cgtaaaccta
    28321 cactaaaaca tataaagggg gaaaacttat gacaattgta ggatgccgta ttgatggacg
    28381 tttgatccac ggacaagtag ccaatctttg ggctggaaaa ctaaatgttt cacgcattat
    28441 ggttgtagac gacgaagttg tcaacaacga tattgaaaag agtggtttga aacttgcgac
    28501 accaccaggt gtgaaattga gtattttgcc agttgagaaa gctgcagcca atattcttgc
    28561 tggtaaatac gatagccaac gtctctttat cgtggctcgt aaaccagacc gcttccttgg
    28621 tttggtagaa gcaggtgtac cacttgaaac ccttaatgtt gggaatatgt ctcaaacacc
    28681 agaaactcgt tctattacac gttctatcaa cgtagtagac aaggatgtgg aagacttcca
    28741 caaactggca gaaaaaggtg ttaaacttac tgctcagatg gttccaaatg atccaatttc
    28801 agactttttg agcttattaa aataggaaaa aaatttttag gaggtcattg ttatgataca
    28861 atggtggcaa attttacttc tcactttgta ctcagcttat caaatctgtg atgagttgac
    28921 gatcgtttca tctgcaggtt cccctgtatt tgctggtttc attactggtt taatcatggg
    28981 agatgtgact actggtttac ttatcggtgg taacttgcaa ctgttcgttc ttggggttgg
    29041 taccttcggt ggtgcttctc gtatcgacgc aacttctggt gcggttcttg cgacagcctt
    29101 ctctgtttca caaggaattg atgcaccgct tgccattact acaatcgctg taccagtagc
    29161 agctctcttg acttacttcg acgttcttgg tcgtatgact actaccttct tcgctcaccg
    29221 tgtggatgct gcaatcgaac gctttgacta taaaggtatt gaacgcaact acttgcttgg
    29281 tgcgattccg tgggctctat ctcgtgccct tccagtcttc tttgcccttg cttttggtgg
    29341 tgcctttgta caatcagtag tagacttcgt tgaagcctac aaatgggttg cagatggctt
    29401 gacacttgca ggacgtatgc ttccaggtct tggatttgca atcttgcttc gttaccttcc
    29461 agttaaacgt aaccttcact accttgctat gggatttggt ttgacagcta tgttgactgt
    29521 tctttactca tatgtaacag gtcttggtgg cgctgttgct ggtatcgtag gtactcttcc
    29581 tgctgaagtt gctgaaaaaa ttggtttcgt gaacaacttc aaaggtttgt ctatgattgg
    29641 tatttctatc gtaggtattt tccttgcagt gcttcacttc aaaaatagcc aaaaagtagc
    29701 tgtagcagca ccttctacac catcagaaag tggggaaatc gaagatgacg aattctaatt
    29761 acaaacttac aaaagaagat tttaatcaaa tcaacaaacg tagcttgttt actttccaat
    29821 taggttggaa ctacgaacgt atgcaagctt ctggttacct ttacatgatc ttgcctcagt
    29881 tgcgtaaaat gtatggtgat ggaactcctg aattgaaaga aatgatgaaa gttcatactc
    29941 aattcttcaa tacttcacca ttcttccata ccattatcgc tggttttgac cttgccatgg
    30001 aagaaaaaga tggtgtaggt tcaaaagacg ccgttaacgg tatcaagaca ggtttgatgg
    30061 gaccattcgc tcctcttggg gatacaatct ttggttcact tgtacctgct atcatggggt
    30121 cagtcgcagc aactatggct atcgctggcc aaccttgggg gatcttcctt tggattgcag
    30181 ttgcagtagc gtatgacatc ttccgttgga aacagttgga atttgcttac aaagaagggg
    30241 ttaaccttat caacaacatg caaagtacct tgacagcttt gattgacgct gcatctgtac
    30301 ttggtgtctt catgatgggt gctcttgtag caacagtgat taactttgaa atttcttaca
    30361 agttgccaat cggtgaaaag atgattgatt tccaagacat cttgaaccaa atcttcccac
    30421 gtttgcttcc agcaatcttt actgccttta tcttctggtt gcttggtaag aaaggtatga
    30481 actctactaa agctatcggt attattatcg tacttgcttt ggctctttct gcccttggtc
    30541 actttgcact tggaatgtaa ttccttatga ctaaatcatt aattttggtg agccatggtc
    30601 gcttctgtga ggagcttaga ggtagcacag aaatgattat gggcccacaa gacaacattt
    30661 acacagtagc tcttcttcca gaagatggcc cagaagaatt tactgctaaa tttgaagctg
    30721 ttattgaagg attggatgat ttcctagtct ttgcggatct tctcggtggg acaccttgta
    30781 atgtggtgag tcgcttgatc atggaaggtc gtgatattga cctttacgca gggatgaatc
    30841 ttccaatggt gattgaattt atcaatgcga gccttacagg cgcagatgcg gactacaaga
    30901 gccgtgctgc agaaagcatt gtgaaagtta atgacctgtt agcgggcttc gatgatgacg
    30961 aagatgaata atactcttcg aaaatctctt caaactacgt caacgtcgcc ttgccgtagg
    31021 tatatgttac tgacttcgtc agtcttatcc ggcaacctca aaacggtgtt ttgagctgac
    31081 ttcgtcagtc ttatccggca acctcaaagc agtgctttga gcagcctgcg gctagtttcc
    31141 tacagatttt agttggaact cgattcaatt catgtgacaa cgtgaaaatc gttagagcat
    31201 tttatataga atatacatgg gaatgtagct tactcccatt cccatattta atagaaaaag
    31261 aggaactcaa tgctacatta tacaaaagaa gacttgctcg aattgggtgc agaaatcact
    31321 acgcgtgaaa tctaccaaca gcctgatgta tggagagaag cttttgaatt ttatcaagca
    31381 aaacgtgaag aaattgcagc cttcctacaa gaaatcgctg ataaacatga ctatattaag
    31441 gttatcttga caggtgctgg gacttctgct tatgtgggag ataccttgct accttatttt
    31501 aaggaagtct atgacgaacg caaatggaat ttcaatgcta ttgcgacaac agatatcgtt
    31561 gccaatccag caacctattt gaaaaaagat gtggcaactg tccttgtgtc ttttgctcgt
    31621 agtgggaatt cgcctgaaag tttggcgact gttgatttgg ccaaatcctt ggtggatgag
    31681 ctttatcaag tgacgattac ttgtgcagca gatggtaaat tggctcttca agctcacggt
    31741 gatgatcgta atctcttgct cttgcaacca gctgtctcta atgatgctgg atttgccatg
    31801 acttctagct ttacgtctat gatgttgaca actctcttgg tctttgatcc tacagaattt
    31861 gctgttaagt ctgaacgttt tgaagttgta tctagtcttg cccgtaaagt tttagacaag
    31921 gcagaagatg tcaaagagct cgttgattta gactttaacc gtgtcatcta tctaggcgct
    31981 ggtcctttct ttggacttgc tcatgaagct cagctcaaga ttttggaatt aactgctggt
    32041 caagttgcga ccatgtatga aagcccagtt ggcttccgtc acggtccaaa atctcttatc
    32101 aacgacaata cagttgtttt ggtctttggt acaacgacag actacactcg taagtacgac
    32161 ttggacttgg ttcgtgaagt tgctggtgac cagattgctc gtcgtgttgt gcttttgagt
    32221 gatcaagctt ttggtcttga aaatgtcaaa gaagtggccc ttggttgtgg cggtgtcttg
    32281 aatgatattt accgtgtctt cccttacatc gtttatgccc aactctttgc tttattgact
    32341 tcactcaagg tagaaaataa accagataca ccgtctccta caggtacagt aaaccgtgta
    32401 gtacaaggtg tcataattca cgaatatcaa aagtaagaca gtgtttatga attcttgaca
    32461 agaggatttg taaattatca gataaaccat agattgtcag tacgctttct atggtttgtt
    32521 tgcttgagag aaatagtaaa aggagaacag aatgaaagca tacacagagc gtgtatttgg
    32581 aaatgttgag ggtgaggatg tcttggccta tcgatttgag acagacggtg gctaccaact
    32641 tgaggttatg acttatggtg cgactatctt gcgctatgtc gcacctgaca aggctggaaa
    32701 ttttgccaat gttatcttgg gatttgatga ctttgatagt tatgtaggca atagtcccaa
    32761 gcatggagca agtgtaggtc ctgtagcggg tcgtattgca ggtgcgacct ttgagctcaa
    32821 tggtaagacc tatgaccttg aggttaataa tgctagcaac tgtaatcaca gtggttcaac
    32881 tggttgggat tccagcttgt ttgaagttga agaagtaagc gatcatggct tgactctcta
    32941 cacagagcgt acagatggga caggagggtt ccctggaaat ctcaagattt ggatcagtta
    33001 tcacttggaa gaaactggtg cctatgaaat cagctacaag gtaacgaccg atcaggatac
    33061 gctggtcaat ccaaccaacc acagctattt caacttgtct ggtgatttca cgcagacgat
    33121 tgaccgtcat gtcttccaac taaacacaga gggcatttac tcaatcgctc ctgacggtgt
    33181 tcctgccaaa actccagaag ccaaccgtga tgtggtcaaa cacgtctaca atggtacctt
    33241 gttgaaggat atctttgcag aagaagatga gcaaatccag ctggcatcag gtttggatca
    33301 tccatttgcc cttcctgcag gccatgacaa tgctggattc ctttatgacc aaaattcagg
    33361 tcgcttcctg cttttcaaga cagaagctcc ttgctttgtg gtctacacag caaactttgt
    33421 ggatgaaagt gtcatcatag gaggtcagcc aatgctacag cacaatggga ttgctcttga
    33481 agcgcaagct ttaccagatg ccattcacag tgaccttaaa ggccaagtca ttcttaaagc
    33541 tggtcaaacc ttcaccagta agacacgtta tgaacttgtt gtgaaataaa aaaagctggt
    33601 caaaaagtct ttaaaattaa aataacgcat attgtcaggt gatgaaaagt ttgataatat
    33661 gcgttttatt atgaaatgat ttactttata ttatcctgaa atggtgttat ttttgagtta
    33721 tctggcttga ctttcttgat ggaaattata taatagttgt aacaataata attacaacta
    33781 gaaaagagga ccatttatga cctatgaata caagagtcac atttatttgg cagagacagc
    33841 tttaaatgta aaggatttgg ccagtcaaac agccttttat cagcaagtta ttggtttaga
    33901 aatcttatct caaactgaga cagagtccat tctaggcctt ggtggaaaag tcttggtaca
    33961 gctgattcaa gcacaagaga gcggagaagt gagggaatat tatggtcttt accatttggc
    34021 cattctcttg cccacacgca aggctttagc tgatgtcttg aaacacctga cagatttaca
    34081 aattcctctt gtcggcggtg cagaccatgg ttacagtgaa gctatttact tggaagattt
    34141 ggagggaaat ggcattgaac tctatcgaga taagccagtt tccacatggg atattcgaga
    34201 agatggacgc attatcggag tgacggaggc tcttgcggcg caggacattt atgagttggg
    34261 ggaaagagta gagcccttta tcctggcaga aggtacaaga atggggcata ttcatctttc
    34321 cgtcaaggat agtcgaaagt ccagccagtt ttatcaaaag gtgttagggc tagagaataa
    34381 attcagtgtg cctggcgcta gttggattgc ggctggagat taccatcatc atttagcagt
    34441 taacgaatgg ggaggaaaag gtctggcttc gcgtaagcaa ggcttaccag gtttagccta
    34501 ctatgtcatc gaagtcgcac ataaaaaaga actgttaacg attgcccaac gagcacaaga
    34561 agttgacgca ccaatcaaat ggatgacatc gatccaattg gaaatcacag actcagatgg
    34621 catcgtgacc cgtattcgtt tagcaaggta aaattaggaa tttttaataa gttataagta
    34681 ttgctagttt gctttttgaa cggtctttgg taacagaact gcgtgagaat tttgacaaag
    34741 aagctgatta gagatataat gaagaaaaat cgagcaagga aaaagaactg acaaattcaa
    34801 agtatattac ttgtttgaaa cgttcagagg gccagttgtg tgggattcaa aagatgattg
    34861 aaggagatcg tgactgtgct gatattgtga cgcaactgac agcagtgaaa tctagtgtag
    34921 agcgcgtgat tgagatgata attaccgaaa atcttactga atgtatcaat cagcccctag
    34981 atgattctga agctcaaaag gaacgcctag aaaaggctat ccgatacttg attaaacgga
    35041 aataaatgaa tgttttgaga cgatatgtgc aaaggtctat taactattag aatagtttaa
    35101 tgtgagtcaa aagaagttgt aaaaaatctc taaaattaaa aaaacgcata gtatcaggtg
    35161 ttgaatgtac tgacccccaa aagttagatt ttttctgtct aacttttggg gtgcagttca
    35221 taagaacctt ggtaatatgc gttttattat gtagagactt atactcttcg aaaatctctt
    35281 caaaccacgt cagcttcacc ttgccgtaga tatggttact gacttcgtca gttctatcca
    35341 caacctcaaa acagtgtttt gagctgactt cgtcagttcc atccacaacc ttaaaacagt
    35401 gttttgagca gcctgcggct aacttcctag tttgcacttt gattttcatt gagtattact
    35461 tcatcttttc ctgaaattga gtttttgccc aactcctctt gattattcta cttgaccggg
    35521 ccaagcattc ataccacctt ctacgttggt aacggtgagg ccttgggagc tgagaaactg
    35581 gcaggtagat gcagagcgga ctcctccttg acaaatgaca tagtattcat ggtcaggttt
    35641 gagttctttg tagccttgct ctaaggtact taatggaaga tttttggcac ctggtgcatg
    35701 tcctgcttgg aattcatgtg cttcacggac atcgataagt tctagatttt cattttggta
    35761 ttttccataa aagtcagcca tgctgatact agtttccata ttctactcct tctgggttaa
    35821 ccattttgta tagtgaataa gcgccgtcaa ggttttgggc ggtaaatcct gcttgcttga
    35881 ggataggctc tgcgatatag ctgcgcaaac cactgtggca gctgacgatg taggcttgtt
    35941 ttttgtccag ttcatcagtt tcctccttga cactttgtca gtttttgata caatagtaca
    36001 aaattagagg aggcaggcta tgattcagaa acatgcgatt cctattttag agtttgatga
    36061 caatcctcag gcggttatca tgcccaatca cgaggggctg gacttgcagt tgccaaagaa
    36121 gtgtgtttat gcatttttag gtgaggagat tgaccgctat gcaagggaag taggggcgga
    36181 ttgtgtcggc gaattcgttt ctgctaccaa gacctatcca gtctatgtca tcaactacaa
    36241 gggtgaggag gtctgtctgg ctcaggctcc tgttggctcc gctccagcag cccagtttat
    36301 ggattggttg attggctatg gtgtggagca gattatctct actgggacct gtggtgtcct
    36361 agctgatata gaggaaaatg cctttctagt ccctgttcgc gctttgcgag atgagggagc
    36421 cagttaccac tatgtggcac cttgtcgtta tatggaaatg cagccagagg ctattgctgc
    36481 tattgaggaa gttttggaag acagagggat tccttatgaa gaagtcatga cctggacgac
    36541 agacggtttt taccgagaaa cggctgaaaa ggtggcttat cgtaaggaag aaggctgtgc
    36601 tgttgtggag atggagtgtt ctgctcttgc ggcagtagct caattgcgtg gggttctctg
    36661 gggtgaattg ttgttcacag cagattctct agcggacttg gaccagtacg acagtcgtga
    36721 ctggggctcg gaagctttta ataaggcgct agaactgagt ttagcaagtg ttcaccacct
    36781 ttagttgtac tggcaaagga tttgttttat cataaaatgt ctagctcata cttttcaaaa
    36841 atatgtttaa acgaggtcac cttcctcttg tcctaggcat gttgaggttg ggaaaaatct
    36901 ttaaaatcag aaaaacgtat catatcaggt gatgaaaatt ttgatactat gcgttttatg
    36961 ttggtaagat ttagagtgag atgaaatgat actcttcgaa aatctcttca aaccaggtca
    37021 gcttcacctt gccgtataga tgttactgac ttcgtcagtt ctatctgcaa cctcaaaaca
    37081 gtgttttgag ctgacttcgt cagttctatc cacaacctca aaacagtgtt ttgagcaacc
    37141 tgtgactagc tttctaagcg atgccttggt tctcattgcc tataatcaaa aagagaaatt
    37201 ttctcctgaa aagcatatag agtagctggc gttaaaagct cctgtcttgc ttttttgacc
    37261 tatagtcaca tctatcaagt attgttcttg cctaagctat caataaaaag gtggcatttt
    37321 ttaggcttgg tgttagtgaa ttttgcctta tcctatctaa gtcatttcga gctttttatg
    37381 gtacaatgga aacatgttat tcaaattatc taaggaaaaa atagagctag gcttatctcg
    37441 tttatcgcca gcccgtcgta tttttttgag ttttgccttg gtcattttac taggctctct
    37501 tcttttgagc ttgccctttg tccaagttga aagctcacga gcgacttatt ttgatcatct
    37561 tttcactgct gtctctgcag tctgtgtgac aggtctctca acccttccag tagctcacac
    37621 ctataatata tggggccaaa taatctgttt gctcttgatt cagatcggtg gtctagggct
    37681 catgaccttt attggggttt tctatatcca gagcaagcaa aagcttagtc ttcgtagccg
    37741 tgcaactatt caggatagtt ttagttatgg agaaactcga tctttgagaa agtttgtcta
    37801 ttctattttt ctcacgacct ttttggttga gagcttggga gctattttgc ttagttttcg
    37861 ccttattcct caacttggct ggggacgtgg tctttttagt tccatttttc tagcgatctc
    37921 agccttctgt aatgccggtt ttgataattt agggagcacc agtttatttg cttttcagac
    37981 cgatttactg gtcaatctgg tgattgcagg cttgattatt acaggcggcc ttggttttat
    38041 ggtctggttt gatttggctg gtcatgtagg aagaaagaaa aaaggacgtc tgcactttca
    38101 tacgaagctt gtactattgt tgactatagg tttgttgtta tttggaacgg caactactct
    38161 ctttcttgag tggaacaatg ctggaacgat tggcaatctc cctgttgccg ataaggtttt
    38221 agttagcttt tttcaaacag tgacgatgcg aacagctggc ttttctacga tagattatac
    38281 tcaggctcat cctgtgactc ttttgattta tatcttacag atgtttctag gtggggcacc
    38341 tggaggaaca gctgggggac tcaagattac gacatttttt gtcctcttgg tctttgcacg
    38401 aagtgagctt ctaggcttgc ctcatgccaa tgttgcgaga cgaacgattg cgccgcgaac
    38461 ggttcaaaaa tcctttagtg tctttattat ctttttgatg agcttcttga taggattgat
    38521 tctgctaggg ataacagcca aaggcaatcc tccctttatc cacctcatat ttgaaaccat
    38581 ttcagctctt agtacagttg gtgtaacggc aaatctgact cctgaccttg ggaaattggc
    38641 tctcagtgtt atcatgccac ttatgtttat gggacgaatt ggtcccttga ccttgtttgt
    38701 tagcttggca gattaccatc cagaaaagaa agatatgatt cactatatga aagcagatat
    38761 tagtattggt taagaaagga aagagcatgt cagatcgtac gattggaatt ttgggcttgg
    38821 gaatttttgg gagcagtgtc ctagctgccc tagccaagca ggatatgaat attatcgcta
    38881 ttgatgacca cgcagagcgc atcaatcagt ttgagccagt tttggcgcgt ggagtgattg
    38941 gtgacatcac agatgaagaa ttattgagat cagcagggat tgatacctgc gataccgttg
    39001 tagtcgcgac aggtgaaaat ctggagtcga gtgtgcttgc ggttatgcac tgtaagagtt
    39061 tgggggtacc gactgttatt gctaaggtca aaagtcagac cgctaagaaa gtgctagaaa
    39121 agattggagc tgactcggtt atctcgccag agtatgaaat gggacagtct ctagcacaga
    39181 ccattctttt ccataatagt gttgatgtct ttcagttgga taaaaatgtg tctatcgtgg
    39241 agatgaaaat tcctcagtct tgggcaggtc aaagtctgag taaattagac ctccgtggca
    39301 aatacaatct gaatattttg ggtttccgag agcaggaaaa ttccccattg gatgttgaat
    39361 ttggaccaga tgacctcttg aaagcagata cctatatttt ggcagtcatc aacaaccagt
    39421 atttggatac cctagtagca ttgaattcgt aaagagggat gacccctctt ttttgatgcc
    39481 caagatggca aatagagaca gaagcccctt gtcttctagt aaaagttctt caaaggctgg
    39541 actttatggt aaaatagaag gaagtgacaa gagagagtaa tactcaatga aaatcaaaga
    39601 tcaaactagg aaactagctg cgggctgctc aaaacactgt tttgaggttg tggatagaac
    39661 tgacgaagtc agctcaaaac actgttttga ggttgcagat agaactgacg aagtcagtaa
    39721 catctatacg gcaaggcgac gttgacgcgg tttgaagaga ttttcgaaga gtataagaaa
    39781 aaatcagttc cctaaaggag cagattatga agttattgtc tatcgctatt tctagctata
    39841 atgcagcagc ctatcttcat tactgtgtgg agtcgctagt gattggtggt gagcaagttg
    39901 ggattttgat tatcaatgac gggtctcagg accagactca ggaaatcgct gagtgtttag
    39961 ctagcaagta tcctaatatc gttagagcca tctatcagga aaataaagga catggcggtg
    40021 tggtcaatcg cggcttggca gaggcttctg ggcgctattt taaagtagtt gacagtgatg
    40081 actggtggat cctcgtgcct acttgaaaat tcttgaaacc ttgcaggaac ttgagagcaa
    40141 gggtcaagag atggatgtct ttgtgaccaa ttttgtctat gaaaaggaag gtcagtctcg
    40201 taagaagagt atgagttacg agtcagtctt gcctgttcgg cagatttttg gctgggacca
    40261 ggtcggaaat ttctccaaag gccagtatat catgatgcac tcgctgattt atcggacagc
    40321 tttgttgcgt gctagccagt tctaactgcc tgaacatact ttttatgtcg ataatctctt
    40381 tgtctttacg ccccttcagc aggtcaagac catgtactat ctgcctgtcg atttctatcg
    40441 ttatttgatt gggcgtgagg accagtctgt caatgagcaa gtgatgatta agtgcattga
    40501 ccagcaactc aaggtcaatc gactcttggt agaccagctt gatttgtccc aagtgagtca
    40561 tcccaaaatg cgagaatatc tgctgaatca tattgaaatc acgacggtga tttccagtac
    40621 cctgctcaac cgatctgaaa cagcggagca tctggcaaaa aaacgccaat tgtggaccta
    40681 tattcagcag aaaaatccag aagtctttca ggctattcgt aagaccatgt tgagccgttt
    40741 gaccaaacat tctgtcttgc cagatcgcaa actgtccaat gtcgtctatc aaatcaccaa
    40801 atctgtttat ggatttaatt aatataagtg ttttataaga gggatttaag aaaaatttta
    40861 actttttctt agtccttttt aatttcagga gattatacta gagtcatcaa ataaagaaag
    40921 actctaagga gaatcctatg aaattcaatc caaatcaaag atatactcgt tggtctattc
    40981 gccgtctcag tgtcggtgtt gcctcagttg ttgtggctag tggcttcttt gtcctagttg
    41041 gtcagccaag ttctgtacgt gccgatgtgg tcaatccgac cccaggtcaa gtcttacctg
    41101 aagagacatc gggaacgaaa gagggtgact tatcagaaaa accaggagac accgttctca
    41161 ctcaagcgaa acctgagggc gttactggaa atacgaattc acttccgaca cctacagaaa
    41221 gaactgaagt gagcgaggaa acaaactctt ctagtctgga tacacttttt gaaaaagatg
    41281 aagaagctca aaaaaatcca gagctaacag atgtcttaaa agaaactgta gatacagctg
    41341 atgtggatgg gacacaagca agtctagcag aaactactcc tgaacaagta aaaggtggag
    41401 tgaaagaaaa tacaaaagac agcatcgatg ttcctgctgc ttatcttgaa aaagctgaag
    41461 ggaaaggtcc tttcactgcc ggtgtaaacc aagtaattcc ttatgaacta ttcgctggtg
    41521 atggtatgtt aactcgtcta ttactaaaag cttcggataa tgctccttgg tctgacaatg
    41581 gtactgctaa aaatcctgct ttacctcctc ttgaaggatt aacaaaaggg aaatacttct
    41641 atgaagtaga cttaaatggc aatactgttg gtaaacaagg tcaagcttta attgatcaac
    41701 ttcgcgctaa tggtactcaa acttataaag ctactgttaa agtttacgga aataaagacg
    41761 gtaaagctga cttgactaat ctagttgcta ctaaaaatgt agacatcaac atcaatggat
    41821 tagttgctaa agaaactgtc gaaaaagctg ttaaagataa cgttaa
//
LOCUS       DAVLCS010000015        40329 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLCS010000015 DAVLCS010000000
VERSION     DAVLCS010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.015"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(<1..255)
                     /locus_tag="VXC78_000902"
     CDS             complement(<1..255)
                     /locus_tag="VXC78_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583009.1"
                     /translation="MKILNIELANVEQTDLGFEHWVDVTYQVPILKNEYTVKLLLLME
                     CRIEDQEVIEYLVSTWKYRDLVLHSVKMYEIEKSESFTILD"
     gene            complement(510..1466)
                     /locus_tag="VXC78_000903"
     CDS             complement(510..1466)
                     /locus_tag="VXC78_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0583010.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNTESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDLEGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     SWKKYTDGNWYWFDNSGEMATGWKKIAEKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFVQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(1470..1802)
                     /locus_tag="VXC78_000904"
     CDS             complement(1470..1802)
                     /locus_tag="VXC78_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0583011.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            complement(1806..2105)
                     /locus_tag="VXC78_000905"
     CDS             complement(1806..2105)
                     /locus_tag="VXC78_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583012.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHAVGDIQKEMVRMNDRMEEIEKGE"
     gene            complement(2115..2465)
                     /locus_tag="VXC78_000906"
     CDS             complement(2115..2465)
                     /locus_tag="VXC78_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583013.1"
                     /translation="MAETNQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTGEPKE"
     gene            complement(2468..2671)
                     /locus_tag="VXC78_000907"
     CDS             complement(2468..2671)
                     /locus_tag="VXC78_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583014.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITNNILSIQLDEQREGNQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            complement(2652..4034)
                     /locus_tag="VXC78_000908"
                     /pseudo
     CDS             complement(2652..4034)
                     /locus_tag="VXC78_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            complement(7278..9149)
                     /locus_tag="VXC78_000909"
                     /pseudo
     CDS             complement(7278..9149)
                     /locus_tag="VXC78_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
     gene            complement(9154..9504)
                     /locus_tag="VXC78_000910"
     CDS             complement(9154..9504)
                     /locus_tag="VXC78_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583015.1"
                     /translation="MAQLTINGVAVKPPKSFKVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSEFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            complement(9513..13118)
                     /locus_tag="VXC78_000911"
     CDS             complement(9513..13118)
                     /locus_tag="VXC78_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583016.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEAARYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKRFSNGQSWDQLDFQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSIATIGLGIGVFLAESIANG
                     LGRQKERIIKALVALFDNIGNIAEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKDFEKVVVTNAPKISSIFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVAPAINSIANAFNGLIDIIQILWEGSWKPFAEFLSNTFGISIETVADL
                     LGGIILEALKLLADTIKLVADGFTAFSDWCKENKEIISTIASVIGTLATVWQGIKFLS
                     WAEQAGGLAGAFELLSSKVSFIVSGIKNLGLALKALTFDKLVSFGETIYLNALYAKDF
                     VVNSGKTIAQLGKTALELGKSALAWTAHTAKMGLATAAEFAHSVAAGVATAATWAFNA
                     ALAVLTSPITLVIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICRAIGEF
                     FSGLWTKLQEIFEPIGQWFGEKFQQAWDAIVNIFTPIGSWFGQRWADVTSALANIGAW
                     FTDMFQKAWTGLTNIFSKLGLWFGERWADVTSVLANVSSWFGNMFTSAYNAVKNAFSS
                     IGGFFSGVWSTVQSIFVNAGQKVGSAVGGAFRSAVNGVLGTIENVVNGFIGMINGVIG
                     MINKIPGVSLGGIGYVSLPRLARGGIVDSPTIAMIGEAGKEAVVPLENTGFIQTLGRV
                     VSSAVVNAMAGISPQGGFSGDGDIVIQIAGHEFGRVAIQEINKEHERAGQTLLKI"
     gene            complement(13105..13455)
                     /locus_tag="VXC78_000912"
     CDS             complement(13105..13455)
                     /locus_tag="VXC78_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583017.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKVFEFWEYAPELFVEEQQAVEQERQRQALLLHKERMRDFAE
                     RHNRKRKEEVNGNS"
     gene            complement(13494..13874)
                     /locus_tag="VXC78_000913"
     CDS             complement(13494..13874)
                     /locus_tag="VXC78_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583018.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVVQ"
     gene            complement(13879..14292)
                     /locus_tag="VXC78_000914"
     CDS             complement(13879..14292)
                     /locus_tag="VXC78_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0583019.1"
                     /translation="MLANGITLSYSKTKGSYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYELGIGDVGELEYKFSYNNSSATAPYRVLRKAADDKEKLYFEQAYPDGTKVTFEG
                     QVSVKLGGGGVNAVIDFTLKIALQSELEFADGVGG"
     gene            complement(14298..14666)
                     /locus_tag="VXC78_000915"
     CDS             complement(14298..14666)
                     /locus_tag="VXC78_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583020.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDKEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            complement(14663..15178)
                     /locus_tag="VXC78_000916"
     CDS             complement(14663..15178)
                     /locus_tag="VXC78_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV0583021.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNAAIKVVQADAR
                     RLVPVNDGELITSIKTRAKMDGDRAIGEVYTNLKYAPYVEFGTGPKGQASHSGISPEV
                     SVTYKSHPWYVHEDQINVGSYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIQ"
     gene            complement(15153..15491)
                     /locus_tag="VXC78_000917"
     CDS             complement(15153..15491)
                     /locus_tag="VXC78_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583022.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            complement(15472..15783)
                     /locus_tag="VXC78_000918"
     CDS             complement(15472..15783)
                     /locus_tag="VXC78_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV0583023.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            complement(15785..15973)
                     /locus_tag="VXC78_000919"
     CDS             complement(15785..15973)
                     /locus_tag="VXC78_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583024.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVT
                     ISDVLEKILPEPEFLEED"
     gene            complement(15963..16145)
                     /locus_tag="VXC78_000920"
     CDS             complement(15963..16145)
                     /locus_tag="VXC78_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEV0583025.1"
                     /translation="MSLLLRRHYIQEEQVNQYSDLENKTLEELKDLAKEAGVAGAYKL
                     TKAEIVEVLEELKSEI"
     gene            complement(16157..17002)
                     /locus_tag="VXC78_000921"
     CDS             complement(16157..17002)
                     /locus_tag="VXC78_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEV0583026.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDATKLKTAVAKEWIKGSELGANMVVSGTFGEVDGVQIVRSKKVDEGKGFLV
                     KVSPSQTQTDDANKYGAFVILLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGGA"
     gene            complement(17009..17593)
                     /locus_tag="VXC78_000922"
     CDS             complement(17009..17593)
                     /locus_tag="VXC78_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEV0583027.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPV
                     DSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            complement(17810..18061)
                     /locus_tag="VXC78_000923"
     CDS             complement(17810..18061)
                     /locus_tag="VXC78_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583028.1"
                     /translation="MLEKAKQLASQEFSRLSGREIKAEDCFVVWFSKTLQNWKALVST
                     NAITSSEPCGNYAEITHNGDKKETYVDVYAKVSNRAIKD"
     gene            complement(18063..18308)
                     /locus_tag="VXC78_000924"
     CDS             complement(18063..18308)
                     /locus_tag="VXC78_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583029.1"
                     /translation="MKYRKKPVVVEAVQWNGNNHKEVIDFAENKIWFDALGNIWIATL
                     EGDMVAKKGDYIIKGVQGEYYPCKLDIFAETYEKTEE"
     gene            complement(18351..18764)
                     /locus_tag="VXC78_000925"
     CDS             complement(18351..18764)
                     /locus_tag="VXC78_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0583030.1"
                     /translation="MIDIALAIAKKAHAGQVDKAGVDYIQHPLYVASQVNTEQEKAVA
                     LLHDVIEDSDITAADLFASGLSNEVVTAVQILTKKKGQSYQEYLGKVKSNNLARVVKL
                     ADLKHNSDLSRLKSVTNTDYERVKKYKNAIHYLST"
     gene            complement(18761..18970)
                     /locus_tag="VXC78_000926"
     CDS             complement(18761..18970)
                     /locus_tag="VXC78_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583031.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSMDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            complement(18972..20609)
                     /locus_tag="VXC78_000927"
     CDS             complement(18972..20609)
                     /locus_tag="VXC78_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEV0583032.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEI
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPENEIKHLQSFSWVGDGSTYSTDIWKNTGKLTSSIKDELLISLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLSYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKVEYVPADM
                     TYKEWYSKYVAKDGEKVYNQDTREAKAKFYSEQLLSKISGVEPKITSDMQRIAGENKL
                     AGLEFRKKTVESLSRKITTDSQAENISLSKATSKINDALRYTTIFDPDTFAKEYLKMK
                     QKLIAEGYKIVKVKNTWLVDGPYKGVNTVVEKDGINFEMQYHTQESFDLKNDSLHELY
                     EKYRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            complement(20518..21987)
                     /locus_tag="VXC78_000928"
     CDS             complement(20518..21987)
                     /locus_tag="VXC78_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0583033.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHNTESSHLKKLKSYYM
                     GEHAILKHTRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            complement(21999..23297)
                     /locus_tag="VXC78_000929"
     CDS             complement(21999..23297)
                     /locus_tag="VXC78_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV0583034.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWRSRSLYRVVKGSRGSK
                     KSKTTALNYVVRLLKYSWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAELRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            complement(23275..23715)
                     /locus_tag="VXC78_000930"
     CDS             complement(23275..23715)
                     /locus_tag="VXC78_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV0583035.1"
                     /translation="MSGLRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHK
                     LLKNPKIKSYIDERLKQLDSEKIADQQEVLGYLTSVMRGETQEQTLISIGELGQTITD
                     IDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            complement(24020..24102)
                     /locus_tag="VXC78_000931"
     tRNA            complement(24020..24102)
                     /locus_tag="VXC78_000931"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24069..24071),aa:Tyr,seq:gta)
     gene            complement(24183..24587)
                     /locus_tag="VXC78_000932"
     CDS             complement(24183..24587)
                     /locus_tag="VXC78_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0583036.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            complement(24660..25031)
                     /locus_tag="VXC78_000933"
     CDS             complement(24660..25031)
                     /locus_tag="VXC78_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583037.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFKH"
     gene            complement(25028..25465)
                     /locus_tag="VXC78_000934"
     CDS             complement(25028..25465)
                     /locus_tag="VXC78_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583038.1"
                     /translation="MTPRYRAWIKTEKRMFFSDDILAIDYENKEIVTQQVYFENGLPD
                     DRDIYCYDFDEIELMQSTGLKDKNGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIG
                     IVKQLEGSWVIDTGSDAVCLWTEIEENEIIGNIYENKEFGGRK"
     gene            complement(25477..25899)
                     /locus_tag="VXC78_000935"
     CDS             complement(25477..25899)
                     /locus_tag="VXC78_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583039.1"
                     /translation="MTETIKLPDYYEPDWKNARYGSLEELKELLLFKRIVKWDKDFLL
                     LEDGTKVTIEMSESDCCASAGGEFQDVSLDAVITNIEIGEPEEIPDHWGTGYKNKVTI
                     FHNQNPVAIANCEAEHNGYYYSVCSLVIGDIHFPVVNA"
     gene            complement(25896..26156)
                     /locus_tag="VXC78_000936"
     CDS             complement(25896..26156)
                     /locus_tag="VXC78_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEV0583040.1"
                     /translation="MKRFIAIWILLSAGLNIWQSIYIKKLEEKRPIVVYKADNAGAEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYDKVKVGDEVLL"
     gene            complement(26314..26802)
                     /locus_tag="VXC78_000937"
     CDS             complement(26314..26802)
                     /locus_tag="VXC78_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0583041.1"
                     /translation="MNKQELIEKYKKLEGVWNAEGAELARQIFLQDLEQLDKPKPVKV
                     PQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPEWFYENNIEKFCLAWLDGYEVEKE
                     KRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEDANFGWVFDCPGIEIEE
                     VE"
     gene            complement(26804..27121)
                     /locus_tag="VXC78_000938"
     CDS             complement(26804..27121)
                     /locus_tag="VXC78_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583042.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWIGYSPSMAQVVIAVYLIY
                     GGN"
     gene            complement(27146..27328)
                     /locus_tag="VXC78_000939"
     CDS             complement(27146..27328)
                     /locus_tag="VXC78_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583043.1"
                     /translation="MADYALYQGDVFVTLGTLAQISSETGITERMLKYYTYTSHQRRH
                     PNGRAVIKIEEEDNEN"
     gene            complement(27344..27775)
                     /locus_tag="VXC78_000940"
     CDS             complement(27344..27775)
                     /locus_tag="VXC78_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEV0583044.1"
                     /translation="MKLTLNIEPKPQSRPRFARRGSFTTTYEDKDMKTWRNHCQLLIA
                     NQYMGQPILEGALRARLRFYIKPPQYISKVKKNQQALLDEIIPVGKKPDIDNYEKALY
                     DSMSGIVFQDDGQIALHDVGKFYSLNPRIEVEIEVMKSLSI"
     gene            complement(27772..28101)
                     /locus_tag="VXC78_000941"
     CDS             complement(27772..28101)
                     /locus_tag="VXC78_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583045.1"
                     /translation="MASKINATERIAIIIDKQKIEVVTTLNYDMSISFDNKDTAPTLD
                     DNGDLFEPVYKCKVKAIPKNDVFFTSLTRVKSNIKTLQEVKKFFEFVNENRENLFEMA
                     GFKGALE"
     gene            complement(28115..28324)
                     /locus_tag="VXC78_000942"
     CDS             complement(28115..28324)
                     /locus_tag="VXC78_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583046.1"
                     /translation="MEWTDWVDWKPETKTDIKTKIENDGYTFPHYDKKNNGVKYVIST
                     LDIKRDCLRLGVPFEDVYPLQTTLF"
     gene            complement(28326..29021)
                     /locus_tag="VXC78_000943"
     CDS             complement(28326..29021)
                     /locus_tag="VXC78_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0583047.1"
                     /translation="MEIDKIIKKDVLEFMETIPDNKIDLIVTDPPYLINYKTNWRKEK
                     HKFSNVIKNDNNPELIKEYIKECYRILKDDTAIYIFCSFDKVDFFKKEIEKYFSVKNI
                     IIWRKNNHTAGDLEAQFGKQYEMIILANKGRKKFNGERLTDVWDFKRVSSDKLLHQNQ
                     KPIELIKRCIVKHSDVGDTVFDGFMGSGTTALAALETDRHFIGTEIDEYYFGIAEERI
                     KNHNAQLSLFDEV"
     gene            complement(29034..29450)
                     /gene="ssb"
                     /locus_tag="VXC78_000944"
     CDS             complement(29034..29450)
                     /gene="ssb"
                     /locus_tag="VXC78_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0583048.1"
                     /translation="MINNVTLVGRLVAPPDLRKTPNNVSSLQGTLAVNRNFKNENGER
                     EADFINFQAWRGTADIIAQYCSKGSLIGLTGRLQVRSYEKDGQRRYVTEVIAESVALL
                     ESRNSQHGQGNSFQNGNSSPFTDPNPFDLPNDGLPF"
     gene            complement(29545..29880)
                     /locus_tag="VXC78_000945"
     CDS             complement(29545..29880)
                     /locus_tag="VXC78_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein Cse60"
                     /protein_id="HEV0583049.1"
                     /translation="MIKTVFFSCDYPHHEAIDDQINSWLAENPGIKLIDIKFQSNVSA
                     VADSGVSAEYWHTSALIIYKVPSENNISSINSNGLGFIISCEKCGSLSIIKGKDVGQN
                     VCYECKGEK"
     gene            complement(29873..30196)
                     /locus_tag="VXC78_000946"
     CDS             complement(29873..30196)
                     /locus_tag="VXC78_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583050.1"
                     /translation="MDIRKISDSVAIYSDGKKLQVIHNLGDEFILDFNVGEDSVWNLN
                     GQVVEIIDMIEPVFKVFSFCSKSGEGMQRLKHAIVHFEIFEQYIRDNQEDLMIWWHNP
                     GGEYD"
     gene            complement(30364..31404)
                     /locus_tag="VXC78_000947"
     CDS             complement(30364..31404)
                     /locus_tag="VXC78_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEV0583051.1"
                     /translation="MQELQVKVTQAQVEIIDREKFEQNINEVVAKYQNYTVTAATIKD
                     DKQTLADLRKLDKQVSDERIRNKKVLSEPADEFDKYVKNAIQPLKDIITKIAGDVKEF
                     EEHQKAVRIDTVKGYLANKSAEYMLDPRLFDEKALEYVKASDFMADGVTLKKATMKSL
                     DDMVTFEFQKQQEFEKAKSAISGLCAEYGMTDSPYIRQLKDLTLAEVFEQIKTDYEFE
                     KQKEELRQDLERAERSNQELLAAQQTKQQEQAPKSTETPNFDPETGKILDGGQILQNE
                     PNALRGAENDLKRYAQKMTLEVYFVDTAEKDCFKAGLSKLGFDFKKNYQVSGYQRIDP
                     LTQAELNEQCGW"
     gene            complement(31414..32178)
                     /gene="bet"
                     /locus_tag="VXC78_000948"
     CDS             complement(31414..32178)
                     /gene="bet"
                     /locus_tag="VXC78_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HEV0583052.1"
                     /translation="MTNNQLATQIKRDITTDPSLLTGADIKKYFDPQNLLTEKQVGQA
                     LALCKGRNLNPFANEVYIVAYQNNSGTEFSLIVSKEAFMKRAERCEGYDGFEAGITVM
                     RNGEMIEIEGSLKLPEDILIGGWAVVYRKDRSHRYKVTVDFNEYVKTDRNGNPRSTWK
                     SMPATMIRKTALVQTLREAFPDELGNMYTDIDGGDTFDAIKDVTPQESREDVVARKMA
                     QIDQFNKEQEANHADPEPTQNEDPIQGELLDGELEY"
     gene            complement(32190..32420)
                     /locus_tag="VXC78_000949"
     CDS             complement(32190..32420)
                     /locus_tag="VXC78_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583053.1"
                     /translation="MTQMTNKGKSFIRAEISEKQKEYIRLLAELRGVTTQELLGQVVE
                     RFIDRNLQLIQDYKNELDDLNSKSRRRIDMNT"
     gene            complement(32540..32683)
                     /locus_tag="VXC78_000950"
     CDS             complement(32540..32683)
                     /locus_tag="VXC78_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583054.1"
                     /translation="MTKIEIENRVWLLANHEEKNELLDLGLTSKARYVKRVLELGKVY
                     AHV"
     gene            complement(32670..32930)
                     /locus_tag="VXC78_000951"
     CDS             complement(32670..32930)
                     /locus_tag="VXC78_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583055.1"
                     /translation="MFKALKTIKKIKQLQKEMHDVSLAFLALQDVGLMPETERSKAKA
                     QTMHDVSHMLKDVLGGKSVDEAMKRLNSEVKIEEVEQEDDKD"
     gene            complement(32943..33197)
                     /locus_tag="VXC78_000952"
     CDS             complement(32943..33197)
                     /locus_tag="VXC78_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583056.1"
                     /translation="MYIISIYVKNTETGNEDFSLIGRDFLPTGHQDYIARVFETKEEA
                     IDYLKSISYIASGVHGNDWVYQNEKLPEIESRCRIWKVGE"
     gene            complement(33198..33419)
                     /locus_tag="VXC78_000953"
     CDS             complement(33198..33419)
                     /locus_tag="VXC78_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583057.1"
                     /translation="MKLLTKLKLRLEVVLKAVNLDWREVAVELMTDLFEERKRRFAFE
                     QENYDLKQELAAYKYKENFDIKARLQGEV"
     gene            complement(33419..33580)
                     /locus_tag="VXC78_000954"
     CDS             complement(33419..33580)
                     /locus_tag="VXC78_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583058.1"
                     /translation="MKRKKEQWKPRIVNIMADGSQVDDLTGYVIPAGHSYYDIILGMN
                     KQSNEEGVA"
     gene            complement(33645..33788)
                     /locus_tag="VXC78_000955"
     CDS             complement(33645..33788)
                     /locus_tag="VXC78_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583059.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     KTV"
     gene            33906..34130
                     /locus_tag="VXC78_000956"
     CDS             33906..34130
                     /locus_tag="VXC78_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015990842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583060.1"
                     /translation="MSKLSRKPNHHVKKLTWSDLDNILISAFTESATDHPSAVIRLSD
                     YEMSKSEIIEEAIAQGYTVIDNSDDFLEFE"
     gene            complement(34441..34707)
                     /locus_tag="VXC78_000957"
     CDS             complement(34441..34707)
                     /locus_tag="VXC78_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0583061.1"
                     /translation="MMVVLANHPNWQVYPDEIAKRKGVSRDTVDSYFKILEKNGYLRI
                     VKKGMGRGKGVRVFRFFSDVKISDFQFEIMKQRLNESISKLSTG"
     gene            complement(34872..35060)
                     /locus_tag="VXC78_000958"
     CDS             complement(34872..35060)
                     /locus_tag="VXC78_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0583062.1"
                     /translation="MQGERLRKWREKEKMSQEELAEKSNVSRTTIHLIESGQSSTVKI
                     RTLQKLAVVFNKQVKDFF"
     gene            complement(35113..35274)
                     /locus_tag="VXC78_000959"
     CDS             complement(35113..35274)
                     /locus_tag="VXC78_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583063.1"
                     /translation="MRPIGYRLNVEVSGIEELKEACKEVSKKAEELQEAIDRLSIIEF
                     ELKAKPVND"
     gene            35321..36127
                     /locus_tag="VXC78_000960"
     CDS             35321..36127
                     /locus_tag="VXC78_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02391 family protein"
                     /protein_id="HEV0583064.1"
                     /translation="MLSIDTQFVDTISKILSDYVSHSEITRMGEVLGYPQNDQNSGLN
                     KHHRVHNIMSDILNKTQDKSNIKLVIEYICNPLRYIDTVSDFENLRLKLNVVLSLKGL
                     TISDDGHVVITTASQTLVEAKKRFESLEHMLRTLNVHPNVLKFCTQELLQENYFHAVF
                     EASKGIFHRIRLLTGSSLDSASLIDQCFKTKEPIMIINGNKLQTLDEQSEYKGLKNLL
                     LTIAHLYRNSKAHKLKYYNPDSVHDALTALTLMSLAHNLLDNCTNTRRLD"
     gene            complement(36062..36355)
                     /locus_tag="VXC78_000961"
     CDS             complement(36062..36355)
                     /locus_tag="VXC78_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583065.1"
                     /translation="MEKLAEVTQEETEKILTYDEIVLLKPITHLHKSIFRQTEYLSEQ
                     LTERLHHLEDYNSPIDEETIRLAEVTIEFYNLLIKSPSISTVVKEIVSEGHKS"
     gene            36598..37047
                     /locus_tag="VXC78_000962"
     CDS             36598..37047
                     /locus_tag="VXC78_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583066.1"
                     /translation="MNNFSFIETLAIAAIPAFVSGMWSYIAAKGNSKHEIDKINIAHS
                     QELENVENQFKQDMEKMQKQHSQELYSLQQTHELRLLELEKVSQLDTQTDQGLKINDL
                     IFKAISGEISADVAIKNISTLSHFANKQQPSDLQKQFMKKLSKKNHK"
     gene            complement(37038..37205)
                     /locus_tag="VXC78_000963"
     CDS             complement(37038..37205)
                     /locus_tag="VXC78_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583067.1"
                     /translation="MNESFLTILGISMIASFITNLIAYLAGKHHLKKKIKNHKMWFDS
                     EIERIKKKYHL"
     gene            complement(37280..37555)
                     /locus_tag="VXC78_000964"
     CDS             complement(37280..37555)
                     /locus_tag="VXC78_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015973618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583068.1"
                     /translation="MNTLNEKAINIFKAVAKETLIQGTYEENFLYSQLETFSTNCRQF
                     TFGWTELADEIERQERYLLDSGFTQEEIDDIRFDAAFAGMLDKMNVA"
     gene            37710..38498
                     /locus_tag="VXC78_000965"
     CDS             37710..38498
                     /locus_tag="VXC78_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0583069.1"
                     /translation="MKLGELLKSYRTEHKLSMDAFCELSDLTKGYISMLEKNEHPKSK
                     KPIVPSYDTIEKIAKGMQISTEDLIDMLDDDQEIQINATPALLSKSPIQTIYDELEPP
                     RQGKVLNYAKRQLDEQENEEETKINEVSENIIRLDDYRQTTYRRVTGVVSAGSGSIQD
                     DDLDMEVSFYEDEIPDDYDAIAYVVGNSMEPKIKNGDYLFIKNTQQVDYNTIGIFQVD
                     GANYVKKLRQGYLESLNPDYEDIHLDESNDIRTIGEVVSVYREK"
     gene            38500..38700
                     /locus_tag="VXC78_000966"
     CDS             38500..38700
                     /locus_tag="VXC78_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583070.1"
                     /translation="MSNESRPMEVIKHNLDCKCHRRREWIRVNDKWHAIEFSVDDPNE
                     PPMTEEEKANVALILQQHLSKE"
     gene            38882..40327
                     /locus_tag="VXC78_000967"
     CDS             38882..40327
                     /locus_tag="VXC78_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0583071.1"
                     /translation="MITTNKVAIYVRVSTTNQVEEGYSIDEQKDKLSSYCDIKDWNVY
                     KVYTDGGFSGSNTDRPALESLIKDAKKRKFDTVLVYKLDRLSRSQKDTLHLIEDVFIK
                     NGIEFLSLQENFDTSTPFGKAMIGLLSVFAQLEREQIKERMQLGKLGRAKSGKSMMWA
                     KTSYGYDYHKETGTVTINPAQALTIKFIFESYLRGRSITKLRDDLNEKYPKHVPWSYR
                     AVRTILDNPVYCGFNQYKGEIYPGNHEPIISKEEYDKTQSELKIRQRTAAENVNPRPF
                     QAKYILSGIAQCGYCGAPLKIMLGVKRKDGSRLKKYECHQRHPRTLRGVTTYNDNKKC
                     DSGFYYKDKLEASVLKEISKLQDDADYLDKIFSGDNAETIDRESYKKQIEELSKKLSR
                     LNDLYIDDRITLEELQSKSAEFISMRATLETELENDPALRKNKRKADMRKLLNAEKVF
                     SMDYESQKVLVRRLINKVKVTAEDIVINWKI"
BASE COUNT        10896 a         9242 c         7109 g        13082 t
ORIGIN      
        1 atcaaggata gtaaaactct cactcttttc tatctcatac atctttaccg aatgcaacac
       61 gagatcacga tacttccaag tgctgaccag atactcaata acctcttggt cctctatcct
      121 gcattccata agtaataata gtttgaccgt gtattcattc ttcaaaatcg gaacctgata
      181 agtcacatct acccaatgct caaaacctaa gtctgtctgc tctacatttg ctagttcaat
      241 atttaaaatc ttcattttta ttcctcctac ttatctattc gtaaaagaag ataaaaagtt
      301 atgaaaaaat cattactttt ttaattcaga cagtactttc agagcaattt tgttaaaaca
      361 aaattggcaa ccaagcgatt taatactatt tgttgacgcc aacaagtcaa ttttcagaca
      421 aacaaaaaaa ccgcaagcct gagcctgcgg tgaaagaaca atttagaaag tttcctttct
      481 atttatttaa ctgtaatcaa gccatctggt tatttaactg taatcaagcc atctggctct
      541 actgtgaact ctggcttgtc tgccagtgtt ccgtctggtt tgaggtagta ccagcctgtt
      601 ccgtctgcgg actggacgaa ggcgtttgat accatagcgc cttctttagc gtctaagtag
      661 taccatgtgt ccttgtactt gacccagcct gtcttcatgg caccttcttc gttgaaatag
      721 taccacttct cagcaatttt cttccagcct gtagccattt cgcctgagtt gtcaaaccag
      781 taccagttgc cgtctgtgta cttcttccag ctgtctgaaa gcatatagcc tgagccatcg
      841 aaataatacc aggtaccgtt gattttctca aacttatctt ttggataaga gccgtctgag
      901 tgtacgtacc agtagccagt gccatttttc tgccagcctg ttgcagcgct caagccgttt
      961 tcgatgtctt gcttaaactg ctcacggcta atgccccaac ttgcaagata tggatatgga
     1021 tccacatggt ctgagtggtt gtttggttgg ttattggtac agtattcatg cgtcttgata
     1081 ccttccaagt cgtctgtatc aagagtcttc ggcaaacctg cttcatctgc tagattgcgt
     1141 aagagttcga tataaaggcg gtagtccgtc atgaactctt ctttagttga atggctttca
     1201 atcagttcaa ccgctgcgta actctcagta ttccaaccgc ccccaacatc ccaacttccg
     1261 ttgttcacag gacctacttg catgacacgg ccatttccga caacatgtga aaagaaccct
     1321 agttcagggt cctttctata gtggtaatca gcctcatttt gagctgttga gttacggttg
     1381 cctgttgaat gggcgtgtac ttgtcgataa ggctgcaccc caacctgtgg caagcctgta
     1441 cgtagtctgt ttctatcgat atccattccc tatcgtcctt tccatgcgtc attcatctgc
     1501 ttcactgctg actctacgaa ggtgtctaag tctttgtcag tcatgctaat attgtatttt
     1561 gtaagctcag cacggacttt agcgcgagcc tgtgccagtt tttcatctcc cttgtagcca
     1621 gtttcagcag ctacttgctc aacggcattt actgcatttt tggccaagat ttcaacgatt
     1681 ttgatggtct tttctccacc tttttgaacc aggtagtcct tgactgcctt gactgcgata
     1741 ccagccaaaa taacaaggat gctgattgct ccattagtaa tgatttcagt aatttgttgc
     1801 atttgttatt ctcctttttc gatttcttcc atgcggtcgt tcatgcgaac catttctttt
     1861 tgaatgtctc cgaccgcgtg agtgattgtg gttaattctg tagtggtctt ttctaggtga
     1921 gtcatcaaac gctcttctcg tctattagag tcggcctttg attgctcgtg caaatccata
     1981 atcttcttct ctcgcttgtc cgaagtcttg ataagatatc gaatgataat aaagaaaagc
     2041 aagataaaca aaatcgccca agctacctga ctttgagcga ttttttcagc ttcttcaatt
     2101 ggcatacaca cctcctattc tttaggttct cccgttggat ccgtccagtc aggattgccc
     2161 tctgcatcaa atttcatgat atagaattca tgattcaaca gaacggcgac gttgattgtt
     2221 gcgattgtac caccccactg gttgaacgcc caaacggttt caacatcctt gagttggcga
     2281 cggccattta cgatcacagg acgtttttga acatcacgat acatatagaa gtcatcgctt
     2341 acattcttgc aacgaatgaa ctctccattt tctttcatgt agcgcaaagc actcgcaaga
     2401 tcaaatggtt ctgtgatttt tgtaaggtct agtaagttat ctgtgttttg atttgtttct
     2461 gccatgtcta ttctcctttg tctgctggtt tagtttgttc atcaagcaga gcttccagct
     2521 catccactcg tgcttgaagt ctttgattcc cttccctttg ctcatccaac tgaatactca
     2581 agatattatt tgtaatcatc gaatttgttg aagttgttga catttcacta attgtcattt
     2641 gtaaggcttg gttaagctgt tctgtgttca ttttctaagt tctccaatct gtgtgttcgt
     2701 tttctatttt caagagcaag ctcctgaatt gctttaaagt gcgatattgg tcaacatgtt
     2761 gttattcatg ctattgtttt ctccattttt tctatttttt gatttaattc ttgaatagcc
     2821 ttgattaagt aaggaactaa agcggtatag tcaatatgca gatagccatc tggattctca
     2881 ggatctcgtg agacaattct tggaacgatg gtttcagcct cttgagctat tagaccaatc
     2941 tcctcatgtt tcttattttc gatgaaatca aatgcaacca ttcttaatct gttgattttg
     3001 tccaaggctt tcacagctgt atctgtgatg ttctctttta agcgtctgtc tgatttttgt
     3061 tccatccaat acttcacgct accgctaccg acctgattcc accaaacaac cgcattcctt
     3121 ccgcctttgg gattccaacc atcaccaagc acatctttac ttccaagttc gataccattt
     3181 gaaaacacag gagaacgaga aaaagtagta ttcccataga agtttgctct cgatgaattc
     3241 gaaaaatcca cttgatcata aaaaccgact tcattcctac agtacatttt cccatcagta
     3301 ttgacgttcc atgctttagg tccggcatag ttccaattat ttccccagtt cgcccagaag
     3361 gctgtccgga ctccatgccc ggcaccattc cccataccaa cagagaactg attgacacct
     3421 gaaatccagc gaccgccacc ctggtcaaat tgaccaagtg tgaatccacc aattcggcct
     3481 tgataggctt ctaggaaggt tgagctagaa atgacggact caaccttaat agagaagata
     3541 cgtttagatg tcagtcggtc aataaaagca tcttttgcag ttaattttct aataagcgca
     3601 tcgtcaactt tcaacttctc agcagttacc gcttcagctt ctaatatcgt agtcgtgacc
     3661 gaaccagctt caaaattggc cgttttgagc ttatcaacca tggcagactt gatgactgct
     3721 ctgtcaatca gggtctctcc agtgatgtgg gtcaatttcc caactaagcg gttatgtcca
     3781 ttggcgccaa gattgattcc agagatgata tctccagccg agttgatgtt ttcaactacc
     3841 catgagccag ctagttgagt catttttgtt tgcgttgctt caagcttctt attcgcatct
     3901 gcgactgcat cttctggatg tggttgccat gttctagatt tataaccttt gtacaagtca
     3961 acttctgtaa tatacaaatc agctgttcct gatgatgagc cattgttatc aaaacgaatg
     4021 taagcattat ccatttctcc ggaattaaaa gttactgaga catcttcgca tctagaggta
     4081 gatagtttct tgctgctaac aactttctta acgattgtga atccatcgct ctcgcctgct
     4141 cttcgtccca aaatataaac atcatagctt gctagagcac tgttgttaaa tcctctaaaa
     4201 ttcagtacat agtcagtatt tcgttcaaga ttaaaacggt gactatacaa aaagttttcg
     4261 tttttagttg cattacttaa acgcataagg tctttctgcc cgttgtgata aaagctatgc
     4321 ttaaccaatc ttcctaaatt ttgagttgag ccccattcat tcgtaccatt tttaaaatca
     4381 ctattcttaa tgaggttagg gccgcttaca ctatatttcc caacctcaac ctgaaacagt
     4441 tgattggtca gagccatgcg agcaacctta tccgcaattc cattttcagt attgcccaaa
     4501 atccgctcgt aaagtttact ggtttcctta acacgctgga agtcagtagt ctctactttt
     4561 cgcactagtt gattggtcac attcgcaaat tgactatcag cattcgcttt gtttgcagaa
     4621 acctgatcag atattctacc catttgtcgt tcagcattat ccttgtttgt agcgacctga
     4681 gtctttaaat ttgaaatctg attatctgcg ccttgtttat tactgtttat ccgatttgaa
     4741 agatttgaaa tctgagtagt ggttccttgc tcactgcttg taagtctatt tgaaaggcca
     4801 ctgatttgac cgcccacatc ttgcttataa gtagttatct gacttgaaat atccgtgaac
     4861 ttaccatcta cagattgacg atagctagcg atttgactag cgatgtcttt attcgcacta
     4921 gttttaacag cttcaatcct ttgattgata cccttaacat cttcttgata agtagcctta
     4981 ccaacgaaat cacgattgac cagctcacgg actgctgtcg cttgtctcgc gctctcctca
     5041 cgagtatagc gctgtagggc ttcctgtcgc tgaccgtctt tatttacata ttcctgaata
     5101 gctgataagt cggttcgcaa gccctgagct gtccgctcaa aggtagcctt agcttcagta
     5161 atgagaccat cagcgtcctc aggcgcagga ctccagtccg tcgccacact accgatttca
     5221 accttgattc ctgttaccca agctgtaccg cttgtagcac cttcaagatt gaatcgcaat
     5281 gatgtcttca attgatcaaa atttgttttt tcagagtagt cataagtgaa tgtaatatat
     5341 ttccaatctg ccgaaccttt atacatacca agcgtagcat aatctggacc actctgtact
     5401 ccggtctcac tattttttct aaaaagataa tgtttgaagc aattaaatac attccaaaaa
     5461 tttcgacctt ggactacatt ttcgtacttg atccaagcgc taaaagtaac tttttggtac
     5521 aaccttgagc tgaaatctgg ttcaaggttg aacgttaaag tagagttgtt ctctagccta
     5581 tagcattctt tttgacctgt gacgtggttt tcaggtaatt tttcaattac tgccccaact
     5641 gtccgggatt ttatccatag attccgccca ccgactttca tcttcgaaaa ttcttcacga
     5701 attttcccag cttcagccac gacaagagtc ttatctgcct tgtccttggt tgcgttcaag
     5761 atttcctgac ggatagagcc agctcgcacc tcaaattcag cctgactcaa cttctgattt
     5821 agtttgttct gcgtgtctgt ctcaagactc ttcacggact gtctaatatt ctcagcagtc
     5881 acgttgagtg agctgatatc cgcttttgtt ctgagacctt cagtcagacg attcacacca
     5941 gcttcgagcg agttggctcg ttgtttgaag gtcgattcta ctgttgaaat ctgaccttct
     6001 atatcttcag gagcttctga ataagaagta tctacatcgc ttatttcaaa cttcggcatc
     6061 caaatccaaa cggttccttc ctggttgaaa ttgaacaacc attcatttgt ggtctgcttg
     6121 gattcgtttg tccaaccttt tggaatatgg acaacatatc gcttaatttc tgtcgacaat
     6181 gtcacatttc cagttttata tccgatattc cctaatcgag ttcttagcat tattccattt
     6241 ttatttgcct tagcataaaa actaatggtt acatcttgat tagtcgtact tccgggaatt
     6301 actttcccga attgacccag agctggataa gtaaccttgg gattacctcc atcacggcca
     6361 gatggattca aacctataat tttaagagcc ttgtgtccaa gatacttact ttcgctatcg
     6421 atagtagccg tatatgtact cgttgtccaa attcctgttt ttgaaatatc ctgcttgaat
     6481 agtgagttca agaatagatt tcgaccggat gcctgcacac tcgctatctt actagagagc
     6541 tcctcagctg tctgcgtgag ttctgacttg ctggctttat ccttggttgc attcaggatt
     6601 tcctgacgga tagagccagc tcgcacctca aattcagcct gactcaactt ctgatttagt
     6661 ttgttctgcg tgtctgtctc aaggctcttc acagattgcc ggatattttc agcagtcaca
     6721 ttgagtgagc tgatatcggc tttagttcta agcccttcag tcagacggct tacaccagcg
     6781 tcgagtgaat cagcacgctg cttaaagttg gattcgacta ctgagacacg gtcttcttgg
     6841 tcttcatacg ctggttgata ggctggaaaa taattaccaa ccgataacat agcgttctca
     6901 atgacgacct gcagaccagc aggaaatcca taattagtac caaaacgaat gaacacatta
     6961 ttagtctgat agtcctcaga agaactagac aagtcaatcg taaactcaaa atgttggcgt
     7021 tcgacagttc cacctttaaa aattaagttt ctgtaggcat accatggatg agcactaaaa
     7081 tgcaccatag caggcatgtc atttgctagg gcgacaggga aagtcacatc aaaagatatg
     7141 cgaacataat cacgcttgaa cctgtcactg ttcttccaga aatcaggaac tatgaatgtt
     7201 cgatagtcgt ataccgcttg acctcctgtt gtgaacgttc ttgaacgtga attcctgaag
     7261 taattccgtg aactacctgc ctgcacactc gcaatccgac tagccagctc ctcagctgtt
     7321 tgcgtgagtt ctgacttgct ggctttacca ttggccaagt tggtcagttc tgacagtcta
     7381 cgagtcgtcg tctcctcata cgtcgcttgc gctgacttca caccagccag ttcattctta
     7441 gtccgactaa gtacttcaac ttgcttggca atctcagctt cagcctgtgc ttgcttcggt
     7501 cgaatatcgt ttgcgatagt tcgttttaga acatccaagt cacctgacaa agccgtctga
     7561 gcgctcgtag tctgcgactt aaacgcttca agtctagcaa cagaatccag ctcaatccgc
     7621 ttcgcttcct gtgcaagcag ggtacttgcg ccagccagtt cttttttggt ctgaacaagt
     7681 gcttcaactt gcttggcaat ctcagcttca acctgtgctt gcttcggtcg aatatcattc
     7741 acgatagtcc gtttcagagc gtccaagtca cctgacagag ccgtttgtgc gctcgtagtc
     7801 tgcgacttaa acgcttcaag tctagcgaca gaatccagcc caatccgctt cgcttcctga
     7861 gcgagtaagc tgcttgcgcc agcatttcgc aaagcttcct cagccttgcg cttagtttct
     7921 ttcaatggcc cgttgtcaaa gctattaaat cgctgattga tagtgtcaga cagttctctc
     7981 ttgacttctt cagctctggc tttggccagt tctacttgat cgttaaagtc ttttttgatt
     8041 ttgtcgacct tttggtcaaa atctttatct gttgcttcaa tctgcgcttg gattttcgct
     8101 tcaatgccac cttgttgctt aatatgcttg gtaatcgtac cctcgtaaga atactgagta
     8161 tcgtttccag ccttactatc tgcgctgata cgccctctca gaccaccttt aaaagtaaag
     8221 ctctgactta acacgggaac tttaaaagtc tctttcttgt tggtctgaat ggttacccac
     8281 tgcccaacct caagtaacaa atgtccttgg tagttgagat tatacggata gtaagttagg
     8341 tttttcagtt tgtaatacag gtcatttaaa gcgctctggg tcatgaagac attgtccagt
     8401 tccaaagacc gacctgtctt cataccgacc gtcagagact tcttgtccgt cttacaagtg
     8461 ataccagcta tctgatactc aatctcactc ttggtcaagc catgcaagaa gtaactgtca
     8521 gcgttgatcg tgatattgga ctcagtcaaa tcacggattt ccatcttgcc ttctctgttg
     8581 aagaaacaag acatcccaat catctgagtc atagcgctca gcatatccct aaaggaaagt
     8641 ttcttgccct caggaacttg ctcaatatga taacgcatcg cgctgattcc gaaatagtca
     8701 ttcgctaact caatgcctgt tttcaggcag atttcctgaa taacctctcg tacttcagct
     8761 gggaaatgca aatccgtcac gtactcacga ttgagcttaa acataccgtc cataagttca
     8821 agtgtggttg tgttgcggtt tcggtcaatc tcaatatcgt tgatgaagta ttcccccatc
     8881 ttgacccact ggtaggtatc cccaaccagt agaccaatct cagggtgcag ggtatccagc
     8941 ttattgaacg tggtaatgat actggtaaag gtaattttac cgctaccagc gcaggttcca
     9001 ccaggcttat aagtatcgcc cttgatgtag ccatactcaa aactagcctc tttgatatcc
     9061 cgtgaagcat aatctccaac acggatagcc agcgtcctgt ttttggcaaa catggctctg
     9121 tcaaattgtc gtctagttaa agcgtccatt ttcttacctc tctaccagat taaatttagc
     9181 gccagaccaa ggtttaaact tctcagtaaa ggtatagcta ggagctgtcc tatcaccgac
     9241 atagaaagtc tttgtgactt ggccatccat ggggtctgga taagacacct caaaaaattc
     9301 agatgataca gcatgtaaaa gctgacttat ttctccctga gtcatcatac cccattcaca
     9361 gtctagtttg cgtttggtcg tgatacggtc acgcaccatg tcgccattgg cattacgccc
     9421 tgtctctcca tcgatatctt gaataccgac tttaaaagat ttgggaggct tcacagccac
     9481 cccattgatt gtcaattgtg ccatttaacc tcctaaatct tgagcaaggt ttgacctgct
     9541 cgttcatgtt ccttgttgat ttcttggata gctacccgtc cgaactcatg gcctgcgatt
     9601 tgaataacga tgtcgccgtc accagaaaaa ccaccttgtg gactaatacc agccatggca
     9661 tttactaccg cactgctgac aactcgccca agggtttgga taaagcctgt attttcaagt
     9721 ggtacgaccg cttctttacc agcttcacca atcatggcga ttgttgggct atcgacgata
     9781 ccaccacggg caagacgagg taggctcaca tatccaatac caccaaggga tacgccaggt
     9841 attttgttaa tcatgccaat aacaccattg atcatgccga tgaagccatt gactacattt
     9901 tcaatagtcc caagaacacc attgactgca cttctgaaag ccccacctac agcgctacca
     9961 accttttgtc cagcattgac aaatatgctt tgaaccgttg accatacacc gctgaagaag
    10021 ccaccaattg aactaaacgc gttcttgact gcattataag cactagtaaa catattccca
    10081 aaccaagaag atacattcgc aagaacactt gtaacatctg cccatctctc gccaaaccat
    10141 aaacctagtt tgctaaagat gtttgttaga ccagtccatg ctttttggaa catgtcagta
    10201 aaccatgccc cgatattagc caaggcacta gtcacatccg cccaacgttg tccaaaccat
    10261 gagccgattg gtgtgaagat attaacgata gcatcccatg cttgctggaa cttctcgcca
    10321 aaccattgac ctattggctc aaagatttct tgtagttttg tccatagacc actgaaaaat
    10381 tcgccaatag ctcgacaaat accactaata aaatcacata gtccttgcca tgcagtttta
    10441 gcaaactcaa caacagtgtc ccagttttgg tagagcaaga caccaatagc aattaaggct
    10501 gcaatagcag caataactaa ggttattgga cttgtcaaaa ctgctaacgc tgcattaaaa
    10561 gcccatgttg cagctgtagc gactcctgct gccacagaat gtgcaaattc cgccgcggtt
    10621 gctaatccca ttttcgctgt atgagcagtc catgctagag ctgatttacc aagttctaaa
    10681 gcagttttcc ctagctgtgc aattgtttta cctgaattga caacaaaatc ttttgcatac
    10741 aacgcattca aatagatggt ttctccgaag ctgaccaatt tatcaaatgt caaagctttc
    10801 aaagctagtc caagattttt aattccgcta acaataaagg aaaccttact acttaataat
    10861 tcgaatgccc ctgcaagtcc tccagcttgt tcagcccaag acaagaactt aattccttgc
    10921 cacacggttg caagcgtacc aatcacacta gcgattgtgg agataatctc tttattttct
    10981 ttacaccaat ctgaaaaagc agtaaaacca tcggctacta gcttgattgt atcagctagt
    11041 aacttcaatg cctctagtat gataccgcct agtaaatcag cgacggtttc aatacttatg
    11101 ccgaatgtgt tagacaagaa ctctgcaaaa ggcttccaac ttccttccca aagtatttga
    11161 ataatgtcaa ttagcccatt aaaagcatta gcaatagagt taatagcagg ggctacatgt
    11221 tcatcataaa cacgacttaa gccatcgcca aatttgttaa cagacctttc aatgctctca
    11281 aatacaggcg caacagtatc taataaactt tggaagattg atgaaatttt aggagcgttt
    11341 gtcacaacga ctttttcaaa atctttaaac aaacttcctg ctaatttact accaacttca
    11401 acaatggtag atgtcaaact caacagagtt gacacaatag cgctaccgat acgaaccgca
    11461 ccagttgagg taatgacgtc gtagaaagca ctagaaaagt cctgagcgat gtttcctact
    11521 gcctcggcaa tgttaccaat attatcaaac aaagcgacta gcgccttgat aatgcgttct
    11581 ttttgccttc caaggccatt ggcaatactt tcggcaagga aaacaccgat acctagcccg
    11641 atagtagcta ttgagcctgt cacttgccct aaagcataag caattttctc agccattcgg
    11701 ttaaaggcat tcacaaccct tgggtcagtg gcgatttctc ccattgtctt agctatttgg
    11761 tctaaggcag tcttaatgcg ttttatacct tctggtctaa atgctgcatc aaaacctttc
    11821 ttgaagaggt caaacaaccc tttgagctta tctccaagac catcaaaaat gctcttgaat
    11881 ttgttgtcca tgtcggtcaa ctcgacttct ggcaagatgt ctttgaaagg tccgccaccg
    11941 cctccctttc ctttaccacc tttgccaccg cctccagacc cgcctgcgtc gtcatctttt
    12001 ggtttttgca agatgttaat ctcatcaaat cccaaaagac ctagcaactc tttagcggcc
    12061 ttcttagcgt ttttggcgga gtctccaaga ttgtcagcaa gtcctcctgc tgaatctcca
    12121 gcgtcgtcta ctgcgtcagc aaggtctcct gctccgcctg cagcatcctt catggcgtta
    12181 cccatgtctc caactgctcc accaacacca tctttcactg ttgctttctt gttgaacatc
    12241 aaagcgataa actcagcgag tttagcagta acgttcttta agaccatagc aaaagagttc
    12301 aagacaggca taatggcatt gataatcggt aacatagagt taccaaggtt caatgctgcg
    12361 tccttcatta gcgacttaaa cagactgata cgaccattta cagaattaga caaggtatct
    12421 ccatacttgg ctgtagcttg ctccaggata gccataagac ggatttgttg ctgggtttga
    12481 aagtcgagtt ggtcccaact ttgaccattt gagaaacgtt taaaagcttc agtggactta
    12541 atcatagcca cattgacgtt gattcctagg tcctcaattg cttcggtgtt ccctagtaga
    12601 cctgagcgaa tccgctccat aacgtctgta atcgtgcgcc ctgaaccttc agcaaccact
    12661 gccgatgtct gcaacatctt agcagtatag gcgcttagct tattggtatc tttgataaat
    12721 ccagaaaaca ggttggagta aaccgcaccg tacctggccg cttcacctac acccatattc
    12781 attgcatttg cgttatcgtt aacccatttt aagaaagatt gcgaactctc gcccatctga
    12841 cgcttgattt ggttcataga cgctgacact tcaagagctg tctgcgttga atacatccca
    12901 acatcaagta atttcttacc aaggattgca aaaccagcga acttagccag cttgccaaac
    12961 gcactaccga tagagttcga ctgttcacga actttggcag tggcattttt cacttggtca
    13021 gatgttcctt tgacctgatt ctcgacttct ttcatcttct tcctgaaagg cgctatctca
    13081 gcgtcaatca tgaccttcaa ttcatcaaga gttgccattc acttcctcct ttcttttgcg
    13141 attgtgtctc tctgcaaaat cacgcatccg ttccttatgc aacaaaagcg cttgtctctg
    13201 tcgttcctgt tctactgctt gctgttcttc tacaaacaac tcaggcgcat attcccagaa
    13261 ctcaaaaacc ttggcatcct tggacaataa caaagaaacg tggttggata tcatctgcga
    13321 aagtctgtat gagtcaataa tcttctcttt acgctcttgg attttgacac ggttgtagct
    13381 ttctatcatt tccctgattt caagcaccgt caaatcccaa aaatcaagag gcttacctcc
    13441 gatgtccaaa aacattgggt aaagtctctc aataatctgc gttaccgtta agattactgg
    13501 actactgtca ttttcttctt ggaagttttc ttgtccttgc ttcctcgtgg agtaaaaccc
    13561 gatacttcaa agagtggcat taacacctct gtcatgaatg ttgtttggtc tccaccattg
    13621 tccacgtatt catcgtataa atcatagaca tcctcaagag aatacccatg ttcatactgc
    13681 tgcaaggcgc cgtgaactaa caacaacata actttcaaag gtggcaaagt gaactcttcg
    13741 cctgcttcag gcatgaaaat cttcagcaag ttcatgccga ttttttcttc cacagttgca
    13801 gcttgatgag atgtcaaacg tagcttcaac tctttttcgt cagtaacttt ccaagttgtg
    13861 tattttaacg ccatttaatt aacctccaac accatctgca aattccaact ctgactgtaa
    13921 agcaatttta agggtgaaat cgataacggc attgacaccg ccaccgccaa gttttacgga
    13981 tacttgacct tcaaatgtga ccttagtacc gtctggataa gcttgttcga agtagagttt
    14041 ttccttgtcg tctgctgcct tacgcaatac acggtaagga gcagttgcgc ttgaattatt
    14101 ataagagaac ttgtactcaa gttctcctac gtccccaata ccaagctcgt acttcttcac
    14161 cgtatcttca agagtagtat tttctacttt ttcgagttca ataccaaact ctggcacttc
    14221 tttcaatcca acaagcttag tatagctacc ttttgttttg ctataagaaa gcgtaattcc
    14281 atttgctaac atatatttta attctccatt ctaaattgaa aaacaagctc tgaatctaag
    14341 tcaacgacac cttcaaaacg catgacctta tgtctcaaat gagacgggtc tggcacgtct
    14401 tggcagtcgg ttcttcgcaa acctaaagac tcaaaaatct gattgatttt aacagctaac
    14461 tcactagtgc tggtatcatc aaaaatatcc accttatagc ggatagagga tttttgttcc
    14521 ttgtcgtcaa accaatcacc tggcttgttt tgttcttcta aaaaaataac gactgggaaa
    14581 gtctcccaat cgctaggata agtatcggtc acattatctg caaccttttg caattcttta
    14641 taaataacag gcttgatatt gatcattgta tttgttctct tatctttcta cggacataat
    14701 tcgaaatatt cttagacaca cgctcttgat tgtctctcaa agctggataa agataaggct
    14761 gagcaggttg accatacatc ttgtaaaact ccccaatctt ttgaaagtgg taagatccta
    14821 cattgatttg gtcttcatgc acataccaag gatgagactt gtaagtcacg ctgacctctg
    14881 gagagatacc agaatggcta gcctgaccct taggtcccgt tccaaactca acgtaaggag
    14941 cgtatttaag gttggtgtaa acttcgccta tagccctatc tccgtccatt tttgctctgg
    15001 ttttgatact agttataagt tctccatcat tcactggtac gagtcttctt gcatcagctt
    15061 ggacaacttt tatagcagca ttgtgtaccg cacgtaagac gatatcctcg ccagtttttt
    15121 tactagctaa ccgtctacat ttagctataa gcctatctgc ccctagtagc cctgacacgc
    15181 tctaactcca aaacttgatg atgtgtgtag acctttttag aaataaccct atgagtcact
    15241 tccgtctgac tatcgataca cacaccatct tttactttga tagtagctga cttgttggca
    15301 tttgcgttca aaatatcatt gacacgctcg ccatacaatt cagattgtag cttgctacta
    15361 gctggccaca attcaaggcg gactgtctca gcttccttgg catacccttc tttcgcgaca
    15421 ccttcctcag tgacagtctt ttcaaaccgt cgcattggat agggtttcag tctactctgc
    15481 ttcaaaaaca tgacctgcca cccttgctag cctgtgcatg cgtattcgct gtagaagacc
    15541 cgtagatagg ccgttttctc cgtagactac tgctatacca ccctcggttc tagaatgctc
    15601 tccttccgct cctgagcggt tgtggagctc gatagcaacc tcaggtatca aaagacttaa
    15661 agcaggtgtc aaagatgtgc gattagtctc tgacaagata agatttgtag ccctcgtttg
    15721 gagcaacatg agaagctgag tatcttcttc gcctgttaat ttcttcagca actctataga
    15781 catatcaatc ctcttctaag aactcaggtt cagggaggat tttctcaaga acgtctgaga
    15841 tagtgacacc gttgctggca atattgtcag ccagctcagc atagcgctcc tcagtaatct
    15901 caagttcctc tcctgccagt cgtttcacat ttgattccca atcatagaaa tcttgtttga
    15961 ttttaaattt cactttttag ttcctccaaa acttctacaa tttcggcttt tgtcaactta
    16021 taagcgcctg ctacacctgc ttctttcgct agatccttca actcttctag agttttattc
    16081 tctaaatcag aatactggtt aacctgctct tcttgaatat aatgacgtcg tagcaataaa
    16141 ctcatatcgt cacctcttac gcgccaccga attttacaac tcgtgtaggg tcgtaaaggt
    16201 aaacgccgta gtgttcatca cctgtgatta cggtagtctt cttcaagata tcgcggtctg
    16261 tttcgatagc cacatcacgt ttaagcaaga taacaaaagc tccatatttg ttagcgtcgt
    16321 ctgtctgagt ttgacttggt gacactttaa caaggaagcc tttaccttca tcaacttttt
    16381 tagagcgcac gatttgcaca ccatcaactt caccgaaggt tccagaaaca accatatttg
    16441 ctccaagctc tgaaccttta atccattctt ttgctactgc agtttttagc ttagtagcat
    16501 ctttagggtt gatgatagca acatactgtg catcttcttc gtcctcaaag atatctagag
    16561 ctttatcgat tgcctcaaga gttgttggag tttctgtaat atgttgtgtt gcagttttag
    16621 ctaccgctac caaatcatta tcgatcttgt tggcaatagc taaaccaagc tggtaagtcg
    16681 cttgacctag tgggtcacca agacctgaca aaagagactc atcggtaatt tcataacctt
    16741 tacctgcttt tttgatggtc atagtagtct ttttagtagt caattggtct ggcgtaattg
    16801 cttggccttc ttcaatttca gtagcgtctc ctgcatactc ccatgctggc actgttaaag
    16861 tgctacctgg ttgaccttca agctttgtct ctacatacgc tagcggtgta aatttaatca
    16921 atttaggtaa tttagcggct accatatccg ccattacttc tggattaacc atagtggcta
    16981 atttagtttg tcctgctgtc attttctatt atcctttcaa tttcttataa agctctgggt
    17041 tcttttgata gagctcattt cgactctgat aacccatacg agcaaattct tcttttgtga
    17101 taccgtcact atcgactggc gcttgtttca ttggagctcc gccttttagt ttttcttgaa
    17161 cgcctttttg cacggcttgc tcccatgatt tctgcaatac agcgacagac tgcgataccg
    17221 tctctgcgct tgtcaaatca actacattta ctaactcaac aggtaagtca cgttcactta
    17281 gcattgcttt agcttctgcg gtcaattcct tgcgagcaat agccttctca cggtcagcta
    17341 gttcttgctc acgctgatcc aactgatatt tttgtttctc gtcagcgttc atcttggcaa
    17401 gtttcttagc ttcgttttcc ttggcttctt gctcagcttc ccatttagag cgttcggcag
    17461 atagcatctt accgatttca gcacgagtga aagttcgttc gtgcttttct tcctgcactg
    17521 aatcaacatt tccttgagtg tcgacagtct cagttgattc agtagataca gttgcattga
    17581 tttcttctga cataattgtc ctccagcgat tacgtcgcca ctcgataatc tcgttttacg
    17641 tccggcgacg gaacagtaca gcttttaatg tcatcggtac agtttggaca atataaaaac
    17701 cgtacggggt tccatacggt tagggcataa gaaaaccgcc tcgatttcga tgcggtttat
    17761 agcaatttat agcagtctat tcctgcaagt caagatgttg gatcacctcc taatctttaa
    17821 tggcacgatt tgaaactttg gcgtaaacat ccacataagt ctctttctta tctccgttat
    17881 gcgtgatttc tgcataattt ccacaaggtt cgcttgatgt aattgcgttc gtactaacaa
    17941 gagctttcca gttttgcagg gtcttgctaa accaaactac aaagcagtct tctgctttga
    18001 tttcacgacc tgataagcgt gaaaattctt gcgatgccaa ttgttttgct ttttctaaca
    18061 ttttattcct ccgttttttc atatgtttct gcaaaaatat ccagcttgca tggataatat
    18121 tctccttgca cgcctttgat aatataatcc ccttttttag ctaccatatc accttcaagt
    18181 gtagcaatcc atatattccc aagtgcatca aaccaaatct tattttctgc aaagtcaatt
    18241 acctctttat ggttattgcc gttccactgc acagcctcga ccactactgg ttttttacgg
    18301 tatttcattc ctcactcctt tctgggtacg aaaaaagcac ttagatctct ctaggtgctt
    18361 aagtagtgaa ttgcattttt atatttttta acacgctcgt agtctgtatt ggtaacagat
    18421 ttcaaacgtg ataaatctga gttatgtttc aaatctgcaa gttttacaac tcttgctaaa
    18481 ttatttgatt ttactttccc aagatattct tgataacttt gacctttttt ctttgtcaaa
    18541 atttgtaccg ctgtaacaac ttcatttgac aagccagacg cgaataaatc ggcagcagtt
    18601 atatcgctat cctcaatcac atcatgtaaa agagcgacag ctttttcttg ttcagtgttg
    18661 acttgactgg ccacatagag aggatgctgt atgtaatcaa cacccgcttt atctacctgc
    18721 cctgcatgtg cttttttagc gatagccaag gcaatatcaa tcatgccgct accatcctgt
    18781 caatataagt aaatgcatca ttttctgaaa tttcttcaaa atccgtaaag tcattaaaaa
    18841 agattttatt aaaccaatcc atgctattaa cccacttttt ttcaatgtca aaaacttgca
    18901 tgacaccatc aatcaaacga agtacttgag cattgttcgt cgttgtgcgg tagtatttaa
    18961 tatctttcat atcacttcac cctctctata tttttaggaa tctcaagccc attgcttaaa
    19021 tcaagcattt ccttaaataa tttcatgcgt tctagatcag atgtattcgt atcacgatac
    19081 ttctcataga gttcatgtaa tgaatcattt tttaagtcga aactttcctg agtatgatac
    19141 tgcatttcaa agttgatacc atctttttca acgactgtat tcacaccttt gtatggtcca
    19201 tctactagcc aagtgttttt tacttttaca attttataac cttctgcgat aagcttctgt
    19261 ttcatcttca aatactcttt tgcgaaagta tcgggatcga aaatagttgt ataccgcaaa
    19321 gcatcgttaa ttttacttgt agcctttgat aaacttatat tttcagcttg gctatctgtt
    19381 gtaattttac gtgataatga ctcaactgtt ttcttcctaa attcaagacc tgccaatttg
    19441 ttttctcctg cgatacgttg catatcactt gtaatttttg gctcaactcc tgaaattttg
    19501 gacaatagtt gttcgctata aaatttcgcc ttggcttctc ttgtatcttg attatacacc
    19561 ttttccccgt ctttcgcaac atacttgcta taccactctt tataagtcat atcggcaggc
    19621 acgtactcaa ctttacctgt ctctggattc cttgctctgc gcttcaactt gctgtagtct
    19681 gcgtcctcat cgtatccgac agtagtagac ctacaccaag ggtgcatagg cggacaattg
    19741 acaccaggga cagccttatc cctatcatag acctgattgt catgctcctg acaaatgcgt
    19801 gatgtacgct tgtctaagac ggccacaaag atatactttt ctatgtctgc ttcttcatag
    19861 ctgagtagct ccatctggtt atgaaaaaag gcggattctg ttcgaaccaa acgccttgca
    19921 tcgttctgac ctacattgaa cctctcagca attgcttgtg cagtttctcg tgtatctctg
    19981 cctgtcatga ggctaatgag gagttcatct tttatgctgg aagtaagttt tcctgtattc
    20041 ttccagatgt ctgttgagta cgtacttcca tctcctaccc aactaaaaga ctgtagatgt
    20101 ttaatctcgt tctcaggaag cccagaaaag ccatatgcta gtcctgtctg ctgttgtagg
    20161 tcaaaggtag ccttgtagta actatccttc atcaggtcgc tataaaaggc atctgagcct
    20221 gtcttctccg aatgatagat agattcacgc atacgatcta aatcgtcgct caaacgctct
    20281 aggcgcttca tgcggaaaga ataagctggg ctgtctaagt cagctagtaa tctttggatg
    20341 ttcgggtcat tcggtctcgc ttcaagtact ttacgaagtt cattcagatt tttcttgtct
    20401 ttcatgttct tcaagacttg tctagcttct acctgactca gaccataatc acgttggaat
    20461 ttatcgaaaa tcttattgat ttccttatcc aagtaagtct tagcttcctg atagacctta
    20521 tcgaactggt ctgcctgctt ttcggccttg tccatctgct ggtaaatcag attggctttc
    20581 ctcttcgccc aatactcctg attcttcatc ctctacctcg tcttcgggtt tcgtgttgtc
    20641 tttgttgaac atcggcatgt cttccatgtt cttctttttc tcttcttcca aggcttccag
    20701 ctcagcgtca gggtcttcca caaacggcaa gagagaaata agctgtctat tggtcacttt
    20761 gccttccaaa ttgttcacaa tctgagagat ttctaataag ttcttaggca aaccacgact
    20821 gaattgtgga acgattgaat gagactctaa agcaatctgc ttcatgccta agtaatgagc
    20881 aaaaatcgca atacgctgac gcaatcctcg cttatagttc gcttccttgg tcttagtaat
    20941 catctcaagg cccatcagct taaattccat ggctacgcct gatgtattcc ctgcgaaatt
    21001 ctcatcagtc aaattaggca catggctaaa tgtgtagatg tcctctttaa gagctgtacg
    21061 caagatttca gtagcacttt cgtccagcgt attcttcaag aactcagccc ttgcactatc
    21121 gcccggcaat tccaaaagac cttcttcaga aagaatcttc attgctacct tagcgtcttc
    21181 tggagtgtct gctaactgcg tgccatacaa gacaagtata gactctacag cctgttcctt
    21241 atcattgaca cgattcccca tcaaggaatt ataagcgtct atcaagctaa tttgttgctc
    21301 gtagtcgcca atcgcaaagt gattattgcg atactcgata attgggattt gaccaaggtt
    21361 gtgaggtgtt gcctcctcgc tctgagttgt tcctgaatct gtacttctca gcaccatgtg
    21421 atagtgcaga ttttcggtaa agacctcagc ctggtgcttg gtagtgtctt tcgtatcgtc
    21481 ttttacttca tagtaataga ccgcaaacaa aggcttccgc tcaatactat catcgtagac
    21541 catgaaagta ttctccggat caatactagt tgaatccaac tcagtcatac cctctttagc
    21601 atagatgtac tcgtaagcac ggccgtagat agccatattt agtgcgttct gcgcatccac
    21661 ttggtcaatc tcagcaccat caaaggctgt aagtagttca tcaatatcac cgtcagcagt
    21721 attgttatac ttgataggat tgcccataaa atagcccgta gccgtgtctg cgatatcctt
    21781 ggcatgatta gctaccgtct tgtaattggg tgcgttcacg ttgcgtctcg tgtgttttaa
    21841 gatagcatgc tcgcccatgt agtagctttt aagcttcttc aaatgtgaac tttcagtgtt
    21901 atgtatcgtt atcaatttgt aaatcaggtc tttcttcaaa gaaccctcat catatccatc
    21961 ccgtggatag gttaaatatt ggtacatgtc tttcctctct atagaccata atcagaacgt
    22021 ctgcggacgg ttgctttccc accttcgata cattgaaggc tgtaacgcaa agcgtccatc
    22081 aagtggttgt ttttatcctc tggtttattc aaccagttgc cttctttatc tcgctggtag
    22141 cagtaactat aaaattcatc catgatgttt ttacaatctg gatgcacata aatagcgtat
    22201 ccttgcaatt tggatacacc tgccataata ctatccttac ctttccgact ctcttttatt
    22261 ctagatatgc catgttctga cctgagctct tcaatcagtc gtaattcagc gctatcagca
    22321 atgatttgtg agcgatgata acctttgtcc tttatcatct tcgcaacttc tttggttatc
    22381 aatccgactt tatacgcctc atcaaagaca taaatctctt tcgtcgtgtc atttatcaac
    22441 gaacaacaca aagcagttgg atcatgagta aaaccaaagt caagaccgat acataactta
    22501 ttagctgaat cttgtagtaa ttcatcttta ttgaaatcct tgacagtcac gttttcgtag
    22561 attaaacctt cagcaactcc ccattcgcca tcacaaacga ttctagcacg tctggggttc
    22621 gtatgataca aatcctcata gcgtttgata tcgacttcat caagccactc attgcatttg
    22681 taagtggttg tagtagcgaa tgtgtcagcc cgtctcgtct cttcatcgaa gaatacacgc
    22741 ttgagccaat gcctctcatt ccacgggtta aatgtgactg tgatttgttt aaagaaatca
    22801 ggtacatcta agctaccacg gatagactca acaaccgtgc tgaacttgtc ttcagtctca
    22861 atttgatatg cttcctcgaa ccatgcccaa caaagactgc cgacatcgac cgtgatagat
    22921 gtgattttga gttcatcatc caaaccacgg aataggattt tttgaccagt cgcttttatg
    22981 gttatttcag gcaaagactc attgaattta aacaaatgag tcacccccaa cacattacac
    23041 gcccatttaa aatccgtata agttgattgc ttatttgtat tcgaatacct acgaataaca
    23101 agcaagttgg cccaggaata tttcaaaaga cggacaacat agtttaaagc ggttgtcttg
    23161 gacttcttcg aaccacggga ccctttgact acacgataaa gacttcttga gcgccagaac
    23221 tgtccgtacc cagctcctac tgtcttaggt aagtcaacga caatatcgtt ttgcttaatc
    23281 tggtatgtct gactcatttg caaacaccac cgttccagaa acatccgcct ctaccttatc
    23341 cgtccaaagc ctatgccgtt taccaagaag ttcagccgcc ttgattctat ctttagctcc
    23401 tacatctata tccgtaatcg tctgccctag ttctccaatg cttatcaagg tctgttcttg
    23461 cgtctctcct cgcatgactg aagttagata acctaagacc tcttgctgat ccgcaatctt
    23521 ttcagaatca agctgtttca gtcgttcatc tatatagctt ttaatcttag gattctttag
    23581 taacttatgt ccttcaacgc ctgccactct atcactagaa acacgataac ctgctttctt
    23641 ataggcttcc gtcgcattac ctgagatgat gtactcatct gcaaatctct tttgttttat
    23701 tctcaatcca ctcaattttc catcaccacc tttcaaacaa tcaaaaaagc cacacgatgt
    23761 gcgaccttct tgcaaggcga ctactacctt gcgtgcgtat taaattttga cttctttttt
    23821 attttttgta gtctttaaaa cctctgaggg aatcaaaccc tctagcttat aacttatccg
    23881 gaatataatt agctacgcaa tcatgcgagg tccagtcgct tccgcaacca tttttaagtt
    23941 aatgagtgat aggagttaat gagtgatatg tgaatcccca cccagaagat ttaactcatt
    24001 ctgggacaca aacactcaaa ggagagggga ggacttgaac ctccaaggcc attacagccc
    24061 cctgacatta caggtaacca tctaccaatt ctgagacctc tcttttcaat tcttgatact
    24121 accattctaa cagattttta gaaccgtgct gttccaaaaa gtcccataag ctcactatga
    24181 ggttagataa cttcttccaa agctaagacc gcctcatttt ttaacctgta gtaggttgta
    24241 cgactcatat tcaaatcata acaaacgcta tcagcggtgc ctttgttgat gtaagtcatt
    24301 cttaatactg ccctgtactt tggattttta agcctattga tcattctacc taattcaagt
    24361 tttctgttaa tgacctcttt agtatcctgc tctatagcct ctttcatcac taccaactga
    24421 gtatagacat catcaacttt tctagtctgt ccaccttgga ctttaacctc ggaccattta
    24481 gggcttgaga gcaaacctgc ctcaagctcg ttaatttcgt ctatacggct ttggatgtcc
    24541 atgtccagat cctgcaactc tttcaagagc tctttagcct tgttcactct ctgtctcctt
    24601 tgtgatataa tagtctttgc gagaactatt agctgaggca gagagtgtct tggctttttt
    24661 taatgcttaa attcgttgac caggtcccgg ataaagaact tccaatcaga ttctctaaac
    24721 gtcaagaaac gatctgtagt aaaatttcta agtcttttat agaaaagcat ctttagttgg
    24781 attgactcac caacactcag taaaataccg gggaagcgat gtactgaatg cactctattt
    24841 ccgtatccag aaatatctaa atgtattaac gtttctggat atatgcgccc catactagct
    24901 tcaactccga actcaacctt aacttcttct acaattggaa cttcgtcaaa aattggtcgt
    24961 gcagaaaata ttggcgacgg cgtttcttgt ttttttcttc ttcctgaata tggatattta
    25021 caaggtctca tttgcgtcct ccaaactcct tattttcata gatgttgccg atgatttcat
    25081 tttcttcaat ttcagtccat aaacatactg cgtcactgcc cgtatcaatt acccaagaac
    25141 cctcaagctg cttaacaatc cctataaatt ccttgtcata ctcatagaaa ccgccaattt
    25201 cgtcagctct acccaaaaat ctagtagttc gtacaatatc gccttcaaag atttccttgc
    25261 cgttcttgtc tttgagtcct gttgattgca tgagttcgat ttcgtcaaaa tcataacaat
    25321 agatatctct atcgtctggt aaaccattct caaaataaac ttgttgtgtc actatttctt
    25381 tgttttcgta gtcaatagca agaatgtcat ctgaaaaaaa catacgtttt tctgttttta
    25441 tccacgctct atatcttggt gtcatgttaa atcctcctaa gcattaacaa ctggaaaatg
    25501 aatatcacca atcactaaag agcatacgct gtaataatag ccgttatgct ctgcttcaca
    25561 attggcaata gctacagggt tctgattatg gaagatagtt actttgtttt tataaccagt
    25621 tccccaatgg tcggggattt cttccggttc tccaatttca atattagtaa tcacagcgtc
    25681 aagtgataca tcttggaact ccccacctgc tgaggcacag caatcacttt cagacatttc
    25741 aatagtgacc tttgtgccgt cttcaagcag caaaaagtcc ttatcccatt tcacaatacg
    25801 cttaaagagc aacaattctt taagctcttc caacgacccg taccttgcat ttttccaatc
    25861 aggctcataa tagtctggta gtttaatagt ttctgtcata gtaacacctc atccccaact
    25921 ttcactttat cgtacacgtc cttcgtaacc acgaacaccc cgtagtcacg aatggtaagc
    25981 gtatatagct tgccatgccg tcctttctcg acgactttac cgaatatctc agcgcctgcg
    26041 ttatcagctt tatagacgac aatcgggcgc ttttcttcta actttttaat gtagatactc
    26101 tgccagatat tcaatccagc agatagcaga atccagatag ctatgaatcg tttcaattta
    26161 tgacctcctc cttcaattta agctcaatct ctaagtaaaa gctttgatca ggtatctcca
    26221 gtatcgctgt agtggtttta ccatcagaac caacgataat ttctccgatt gccaaaacta
    26281 agtctccaat tgtgctattt agcgtaaggc tcatcactcc acctcctcaa tctcaatccc
    26341 tggacaatca aacacccagc cgaagtttgc gtcttctagt tctttttgag tacctttata
    26401 attcctagct gttatatctt gactaaaata aagagtactc cctgattgcg atttgaccaa
    26461 aggctgccta ttttttaaag tcaccaaata ccgcttctct ttttcaacct cgtagccgtc
    26521 aagccaagca agacagaatt tttcgatgtt attttcgtaa aaccactcag gaactttctt
    26581 atcataatga tcttcaatta ctctcattgc accgtaaaca tgaaaattgt ttttcttttt
    26641 aaattctata tattccgcca cacactgcgg aactttgact ggttttggtt tatctagttg
    26701 ttccaagtct tgcagaaaaa tttgacgagc tagttctgct ccttcagcat tccatacacc
    26761 ctcaagtttt ttatatttct caatcaattc ctgcttattc atcttagttt cctccataaa
    26821 tcaaataaac tgcaataact acctgagcca tgcttggcga atagccaatc caatcatcaa
    26881 actccttaga ttttggcaac caacccttag tagctcccaa atcatagtct gtaggctttt
    26941 catcagcaaa gatgcattcc atcgctccca taaacgtcat accatcttct gccatttccc
    27001 aaaaatagtc cgcccggtct ttcaccgctt gtggtaaatc ttgcttggga ggttgcggct
    27061 tcccgtcttc taccgtccag ttgtatactt cattaacttt ttgctttaac tcttccatca
    27121 tcttccaact tcttcacttt ccgtcttaat tctcattatc ttcctcctca attttaataa
    27181 cggccctacc gtttgggtgt cgtctttggt gtgatgtgta agtgtaatac tttaacatcc
    27241 tttcagtaat tcctgtctcg ctactgatct gcgctaatgt tccaagcgta acaaacacat
    27301 caccttgata taatgcgtag tcagccatct gctcctcatt tcttcaaata ctcagggatt
    27361 tcatgacctc aatctcaacc tctatccgtg gatttagact gtagaacttg cctacatcat
    27421 gtagcgctat ctgaccgtcg tcctggaaga cgatccctga catgctgtca tatagcgctt
    27481 tttcgtagtt atctatgtca ggctttttgc ctactggtat aatttcatcc aggagggcct
    27541 gttggttctt cttgacttta gaaatgtact gaggaggttt gatataaaat ctaagccgtg
    27601 ccctcaaagc tccctcaagg ataggctgac ccatgtactg attagcaatg agcagctggc
    27661 aatgattgcg ccatgttttc atatccttgt cttcgtaagt tgtggtaaaa ctcccacgtc
    27721 ttgcaaacct tggccgtgat tgaggtttag gctcaatgtt cagggtcaat ttcattcaag
    27781 agccccctta aatcctgcca tctcaaagag attttctctg ttttcgttta cgaactcaaa
    27841 gaatttttta acctcttgta gcgtcttgat gttgctcttg actcgtgtta atgaggtgaa
    27901 aaatacatca tttttgggaa ttgccttaac tttgcacttg tagaccggtt caaaaaggtc
    27961 accattgtca tctagtgtag gagccgtgtc tttgttatca aagctaatgc tcatatcata
    28021 gtttagagtc gtaacgacct ctattttttg tttatcaatg atgatagcaa tacgttctgt
    28081 cgcattgatt ttacttgcca tgttctttct cctgttaaaa aagtgtcgtt tgcaaagggt
    28141 acacatcttc aaacggtact ccaagtctta gacagtctcg tttgatgtcc agtgtagaga
    28201 tgacgtactt gacgccgttg tttttcttgt catagtgtgg aaaagtgtac ccgtcatttt
    28261 caattttggt tttaatgtcc gttttggttt caggtttcca atccacccaa tccgtccact
    28321 ccatctcata cctcatcaaa taaacttaat tgagcgttgt ggttttttat ccgctcctct
    28381 gctataccaa aataatattc atctatttca gttcctataa aatgcctatc cgtttctaac
    28441 gctgctaatg ctgtcgtacc gcttcccatg aaaccatcaa aaacagtatc cccaacatca
    28501 gaatgtttaa caatacatcg ttttatcaat tcaataggtt tttgattttg atggagtagt
    28561 ttatctgaac ttactctctt gaaatcccaa acatctgtca gtcgctcacc gttgaatttc
    28621 ttccgtcctt tgtttgccaa tataatcatc tcgtactgtt ttccaaactg cgcctctaaa
    28681 tcgccagcgg tatgattatt ttttcgccat ataataatat tttttactga aaaatacttt
    28741 tcaatttctt ttttaaaaaa atcaaccttg tcaaatgaac agaatatata aatagccgta
    28801 tcatctttta aaattcgata acactctttt atatactctt ttatcaattc aggattgtta
    28861 tcatttttga taacatttga aaatttatgc ttttctttcc gccaatttgt tttataattt
    28921 atcaaataag gcgggtctgt tacgattaaa tcaattttat tatcaggaat tgtttccata
    28981 aattccaaga catctttttt tataatctta tctatttcca ctaactgtcc ctcctaaaac
    29041 ggcaaaccgt catttgggag gtcaaagggg ttaggatcgg taaaaggtga gctattccca
    29101 ttttggaaac tgttgccttg tccgtgctga ctgttgcgac tctctagcag agctacactc
    29161 tcagcgatta cttcagtcac atatcgacgc tgaccgtctt tctcgtaaga cctaacttgt
    29221 aagcgccctg tgaggccaat aagtgagccc ttgctgcaat actgagcaat gatgtcagct
    29281 gtacctctcc aagcttgaaa attgataaaa tcagcctcac gctctccatt ttcgtttttg
    29341 aaattgcgat tgactgcaag cgtgccctgt aaactagata cattattagg cgtttttcgt
    29401 agatcaggag gcgctacaag cctcccaacc agtgtgacgt tattgatcat ctgatttgtc
    29461 cccctctagt gctacgctct cccaagagat accctaaaaa catccatagg atagccatcc
    29521 caatctcttt gataaaatca ttcattattt ctctcctttg cattcataac atacattttg
    29581 acctacatct tttcccttga ttattgataa gctaccacat ttctcacagc tgattatgaa
    29641 acctaaacca tttgaattaa tactgcttat attgttctct gagggaactt tgtaaataat
    29701 caatgcggat gtatgccaat attcagcact gactccactg tcagcgacag cagacacatt
    29761 tgattgaaat ttgatgtcaa tcaacttaat gcctggattt tcggcaagcc agctatttat
    29821 ttggtcgtca atcgcctcat gatgtggata atcacatgaa aaaaatacgg ttttaatcat
    29881 attcccctcc tggattgtgc caccagatca tcaggtcttc ctgattatct ctgatgtact
    29941 gctcaaatat ttcaaagtgg acgatagcat gttttaagcg ttgcataccc tctccagatt
    30001 ttgagcaaaa gctgaaaact ttaaagacag gctcaatcat gtcaataatt tctacgactt
    30061 ggccattgag gttccagacg ctatcctctc ccacattgaa atcaaggata aactcatccc
    30121 ctaggttgtg gataacctgc aatttcttgc cgtccgagta gatggctacg ctgtcagata
    30181 tttttctgat gtccatggtt accctcccca ttgactctgg agaaatatcc caagattttt
    30241 ctatctccaa tttccttttt tcgccataca gagtcgctaa taggtcctct atttttccta
    30301 ttaactcatc aggcacccca tattcagcca attcttctga aattttttca atttctgtca
    30361 tacttaccac ccacattgtt catttagctc agcctgagtt aatggatcga tacgttgata
    30421 accgctgact tgatagttct ttttaaaatc aaatccgagt ttacttagac cagccttgaa
    30481 acagtctttt tcggctgtgt ctacaaaata cacctctaaa gtcatttttt gggcatatcg
    30541 ttttaggtca ttttcagccc ctctaagagc gttaggctca ttttggagga tttgtccacc
    30601 gtccaagatt ttgcccgttt ctgggtcaaa atttggggtt tccgttgatt ttggagcctg
    30661 ttcttgctgt ttggtttgtt gggctgctaa aagctcctga ttagatcgct ctgctcgttc
    30721 tagatcctgt ctgagttctt ccttttgctt ttcaaactca taatcagttt tgatttgttc
    30781 aaagacttca gcaagagtca agtctttcag ctgtctaatg taaggtgagt cagtcatgcc
    30841 gtactcagca cataaccctg aaatagctga cttggctttt tcaaattctt gttgtttctg
    30901 aaattcaaat gtgaccatgt catcaagtga cttcatagtg gcttttttaa gcgtcacgcc
    30961 atctgccata aaatcgctag ctttgacata ctcaagggcc ttttcatcaa agagacgagg
    31021 atccagcatg tactcagctg atttgttggc taggtagcct ttgactgtgt caattcggac
    31081 agccttttga tgttcttcaa actctttgac atcaccagca attttggtaa tgatgtcttt
    31141 tagaggctgg atggcattct tgacatactt gtcaaattca tcagctggtt cagataagac
    31201 tttcttattc ctgatccgtt catcagaaac ctgcttgtct aattttcgta gatcggcaag
    31261 tgtctgcttg tcatccttga tagttgcagc cgtaaccgtg taattttgat actttgctac
    31321 aacctcattg atattctgct caaatttctc acggtcaatg atttcaacct gtgcttgtgt
    31381 tacttttacc tgtaattctt gcatgttgtc ctcctaatat tcaagttcac cgtctagcaa
    31441 ctcgccctgg attggatcct cattttgagt aggttcagga tctgcatgat ttgcctcttg
    31501 ctctttgttg aattgatcaa tctgagccat cttgcgtgct acgacatcct cacggctctc
    31561 ttgaggtgtg acgtctttga ttgcgtcaaa tgtatctcca ccatcgatgt ctgtatacat
    31621 gttcccaagt tcgtcaggga aagcctctct aagagtctgc actagagctg tttttctgat
    31681 catagtggct ggcattgatt tccaagtgct ccgtggattg ccatttctgt ctgttttgac
    31741 atactcatta aagtcaactg tgaccttata tctgtgtgaa cggtctttac gatagacaac
    31801 ggcccaacca cctattagaa tgtcctcagg taatttaaga gagccctcaa tctctatcat
    31861 ttctccattt ctcatgacag taattccagc ctcaaaacca tcatatccct cacaacgttc
    31921 agcacgtttc ataaatgcct cttttgagac aatcaagctg aactctgtgc cgctattgtt
    31981 ttgataggct acaatgtaga cctcgttagc aaatgggtta agattgcgac ctttacacaa
    32041 ggctagagcc tgacctactt gtttttcagt cagtaggttt tgtgggtcaa aatacttttt
    32101 gatgtctgcc ccagtcaata aacttggatc agtagtgatg tcacgtttta tctgtgttgc
    32161 taattgatta ttagtcatct tgttttctcc tatgtgttca tgtcaattct gcgtctagac
    32221 ttactattta agtcatctaa ttcatttttg taatcttgaa taagttgcaa attccggtca
    32281 atgaagcgtt ctacaacttg acctagaagt tcttgtgttg tcacgcctct caattcagca
    32341 agaagtctga tatattcttt ttgtttttca gagatctctg ctcttatgaa cgactttcct
    32401 ttattggtca tctgcgtcat ttttttctcc tttaggctag caatctccta catagatcca
    32461 ttgaccagcg ctgaaaatcc aatcagctgg gtcaagttct tctcgttctt caggcggttg
    32521 cattatatct ctgtcataat taaacatgag catacacctt cccaagctcc agaactcgtt
    32581 tcacatatct agccttggat gttagcccaa gatccagcaa ttcgtttttt tcttcatgat
    32641 tggccaaaag ccagacacgg ttttcaattt caatctttgt catcttcctg ctccacctct
    32701 tcaattttca cttcgctatt tagacgtttc atggcttcat ctaccgactt gccgcccagg
    32761 acgtccttga gcatgtggct tacatcgtgc attgtttgag ccttcgcctt gcttctttca
    32821 gtctctggca tcaatccgac atcttgtaga gccagaaagg ctaaactgac atcgtgcatt
    32881 tctttctgaa gctgtttgat ttttttgatt gtttttagtg ctttaaacat attgttctcc
    32941 ttttattctc ctactttcca aattcggcaa cgtgactcaa tttctggtag tttttcattt
    33001 tgataaaccc aatcgttacc atgaacacct gatgcgatgt aagatataga ttttaagtaa
    33061 tcaatcgctt cttcttttgt ttcaaaaact cttgcaatat agtcttggtg ccccgtcggt
    33121 aagaaatcac gtccaatcaa actgaaatcc tcgtttccag tttcagtatt cttgacataa
    33181 atcgatataa tgtacatcta cacttctcct tgcagtctag ccttgatatc aaagttttct
    33241 ttgtacttgt aggcagcaag ctcttgtttc aaatcgtagt tttcttgctc gaaagcaaag
    33301 cgacgtttgc gctcctcaaa taggtcggtc atgagttcga ccgctacctc tcgccagtca
    33361 aggttgactg ctttaagaac tacttcaagt ctgagtttta acttggtaag taatttcatt
    33421 aagctacgcc ctcctcgtta gattgcttgt tcatgcctaa aataatgtca tagtaggaat
    33481 gaccagcagg gatgacatag cctgtcaaat catcaacttg agagccatct gccatgatgt
    33541 ttacaattct tggtttccat tgctcttttt ttctcttcat gttataatta cctcgaatac
    33601 ttttgttgag cgcctgattg ccgtcaggtg ctttttgttg tcttctagac tgtcttactt
    33661 tccatcgccc tgagttctat ctcatggctg acttgtttca atagcttctc acacgctatt
    33721 ttagcttctc tgtacgttgt agattcgctg atgaagtagt cagcaagttc tatgatttta
    33781 tcttccattc aacctcctat atcagtcttg agactgatgt aattccttcc taaattgcta
    33841 taatactctt gactaggacc tctcactgtt ttagtcaaaa tttcaataga aaggaggaaa
    33901 attatatgag taaacttagc agaaaaccaa accaccatgt taaaaaactt acttggtcag
    33961 accttgataa cattctgata tctgctttta cagagtcagc gactgatcat cctagtgcag
    34021 taatccgatt atctgattat gagatgtcta aatccgaaat tatcgaagaa gcaattgcac
    34081 aaggttacac agttattgac aattctgatg acttcttaga gtttgaatag cgtgggtcaa
    34141 atatgatatg ttagtactat ttgcttcaac atatcttttt aatttagcaa tctgttcatc
    34201 ggattgcctt ttctttcttc ctgaatacgg atattttctt ggtctcattt cctcacctcc
    34261 tttgtattta ttttttctac cctctctttt atttatttag agaagtagga ctggttgtct
    34321 tttaatattt attgttattt aatacttgtt gttagttaat atttattagt gcctaaattt
    34381 tctgatttgt aaaatacaga tttgtaaaat acagatttgt aaaaatcgga aatgtaaatt
    34441 ctaacctgtg gataacttag atatactttc attcaatctc tgtttcatga tttcaaattg
    34501 aaaatcggat atttttacat ctgagaaaaa tctgaaaaca cgaactcctt taccacgtcc
    34561 catgcctttt ttaacaattc gtaggtagcc atttttttct aatattttga agtagctatc
    34621 aactgtgtct cgactaacac cttttcgttt agctatttca tctggataga cttgccaatt
    34681 tgggtggtta gctaggacaa ccatcataat accaacagct gtaaagtcca gttttgggtc
    34741 attgataaaa ctattactaa cagcagtata attttcagtc gcattcttga aagataaatt
    34801 gacaatctaa atttttaaag tctgtcatac gctctccttt ctttttttgt ttaatttgtt
    34861 aaacattttc tttaaaaaaa atctttcact tgcttattaa aaactactgc taatttttga
    34921 agtgttcgaa ttttcactgt tgacgactga cctgattcaa ttaagtgtat tgttgttcga
    34981 gaaacatttg acttctctgc aagttcctct tgagacattt tctctttttc acgccatttt
    35041 cttaaacgtt ctccttgcac gcactcaccc ccttgtgtta atagttgccc tgtcgtttct
    35101 agatagattg ttctaatcat tgacaggctt ggcttttaat tcaaattcaa taatactaag
    35161 tcgatcgatt gcttcttgca attcttcggc tttttttgat acttctttac aggcttcctt
    35221 tagttcttca atacccgaaa cttcaacatt aagccgatat cctattggtc tcatttcttt
    35281 ctcctttttg atataatgtt taataaaaac gaggtttgct atgttaagta ttgatacaca
    35341 atttgtagat acaatcagta aaatactatc tgattatgtt tcacattctg aaatcacaag
    35401 gatgggagaa gttttaggat atccccaaaa cgaccagaac tctggactca ataaacacca
    35461 tagagttcac aatatcatgt ctgatatact caacaaaaca caagataaat caaatatcaa
    35521 acttgtaatt gagtatatct gcaatccttt gaggtacatc gatacggttt cagattttga
    35581 aaacttaaga ttaaaactaa atgtcgttct ttccctaaaa ggccttacca tatcagatga
    35641 cggacatgta gttattacta ctgcttcaca aactttagtt gaggcaaaga aacgatttga
    35701 atcacttgaa catatgttga gaacattaaa tgttcatcca aatgttttaa aattctgcac
    35761 ccaggaactc ttacaagaaa attattttca tgctgtattt gaagcaagta aaggaatctt
    35821 tcaccgcatt cgtttgctaa ccggttcgtc tctggactca gcaagtctaa tagaccaatg
    35881 ttttaaaacc aaagaaccca tcatgattat caacggaaat aaattacaaa ctctcgacga
    35941 acaaagtgaa tataaaggat tgaagaattt acttctgaca atcgcacatc tttatcgtaa
    36001 ttccaaagca cataaactta aatactacaa tccagatagc gttcatgatg ccttaactgc
    36061 cttaactctt atgtccctcg ctcacaatct ccttgacaac tgtactaata ctaggagact
    36121 tgattagtag attataaaat tctatagtca cctcagctaa tctaattgtt tcttcatcta
    36181 tgggactatt gtagtcctca aggtgatgaa gcctttcagt caactgctct gataagtatt
    36241 ctgtttgcct aaagatagat ttatgaagat gagtaattgg ttttagcaac acgatttcat
    36301 cataagttaa tattttttca gtctcctctt gagttacttc tgctaatttt tccataccag
    36361 aaatatcaac attaacatgc ggctgttcca ttatcgttcc ccctcgtctt actttccagc
    36421 gccctgagtt ctatctcatg actgacttga agaaatagct tctcacacgc tattttagct
    36481 tctctgtacg ttgtgttttc gctgatgaag taatcagcaa gttcaatgat tttatcttcc
    36541 aattctaact acctttcaaa tgtggtataa tcaaaataaa acgattggag aaatcttatg
    36601 aataatttta gttttataga aacacttgcg atcgctgcca tacctgcctt tgtttctggc
    36661 atgtggtctt acatcgctgc taaaggaaac agcaagcatg aaattgataa aattaacatt
    36721 gcacactcac aagagcttga aaatgtcgaa aatcaattta aacaagatat ggaaaaaatg
    36781 caaaagcaac actcacaaga actttattcg ctgcaacaaa ctcacgaatt aagattactt
    36841 gaacttgaaa aagtatctca actagacact caaaccgacc aaggattaaa gataaatgac
    36901 ctaattttta aagctatttc aggagaaata tctgcagatg tagcaataaa aaatataagc
    36961 actcttagtc atttcgcgaa caagcaacaa ccttccgatc ttcaaaaaca atttatgaaa
    37021 aaattatcca agaaaaatca caaatgatac tttttcttga tacgctctat ctcagaatca
    37081 aaccacattt tgtggttttt aattttcttt ttcagatgat gcttaccagc taagtaagca
    37141 attaaattcg tgataaaact agcaatcatt gatatgccta gtatcgtaag aaaagattca
    37201 ttcatcgttc tactcctttc tctctttttt cgctctatga gcaacaacct gccaaggatt
    37261 cgaaccttgg tgataccaat caggctacat tcattttatc aagcattcct gcgaacgctg
    37321 catcgaaacg aatgtcatcg atttcctctt gagtgaaacc agaatcgaga aggtaacgct
    37381 cttggcgttc aatctcatct gctaactctg tccatccaaa agtgaattga cggcagttag
    37441 tactgaatgt ttcaagttgg ctgtagagga agttttcctc gtaagtgcct tggattaaag
    37501 tttccttagc tactgcttta aagatgttga ttgctttctc gtttaatgtg ttcatggtgt
    37561 ttccctccgg tttgtttttg ttatttcctt aagcttgatt atagtttaac acgttaaaca
    37621 caaaatgtca agtgtgttaa acaaaaaaat ttactttttt tatttaaaga tgtataatgg
    37681 attaaacaat atatagaaag gggttttaaa tgaagttagg agaattgcta aaatcatata
    37741 gaacagagca taaattatca atggatgctt tttgtgaatt atctgattta acaaaaggat
    37801 atatttctat gcttgaaaaa aatgaacatc cgaaatcgaa aaagcccatt gtcccatctt
    37861 atgacacaat agaaaaaatt gctaaaggaa tgcaaatttc tacagaagat ttaattgata
    37921 tgcttgatga tgatcaagaa attcaaatca acgctactcc agctcttctt tcaaaatccc
    37981 caatccaaac catctacgac gaactagaac cacctagaca gggcaaagtc ctgaattatg
    38041 caaagaggca actggacgag caggaaaacg aagaagaaac gaagataaac gaagtatcgg
    38101 agaacatcat cagactggac gactacagac agactactta ccgacgtgtt actggggttg
    38161 tctctgctgg tagtggttcg atacaggacg acgatttaga tatggaggtt tcgttctatg
    38221 aggatgaaat cccagacgac tacgacgcta tcgcttatgt cgtcggcaac tctatggagc
    38281 caaagataaa gaatggtgac tatcttttta taaagaatac ccaacaggtt gattataaca
    38341 ctatcggcat cttccaagta gacggcgcta actatgttaa gaaactgcgt cagggatatc
    38401 tggaaagctt gaatccagat tatgaggata tacacctaga cgaaagcaac gacatccgaa
    38461 ctattgggga agttgtcagt gtgtataggg agaaataaca tgagtaacga aagtagaccg
    38521 atggaagtga ttaaacacaa cctagattgc aaatgccaca gacgaagaga gtggattaga
    38581 gtaaatgata aatggcatgc tatcgagttt tcggtagacg atccaaacga acctcctatg
    38641 acagaggaag agaaagccaa cgtggcctta attcttcaac aacacttatc gaaagaataa
    38701 aaccaactgt ttccaaaatg gaaataattg caaacaaaaa aagccccacg ctctcaaaac
    38761 tttggcgagt ctgagcgtga ggcatgtgac aggaaaagat tttcatggag ataacctctc
    38821 atgatgtctt ttcttgtacc cattttatca ttttttagga aattttgaaa gaggtactac
    38881 tatgataaca acaaataaag tagctatata tgtcagggta tcgacgacaa accaggttga
    38941 ggagggatac tctatagatg agcaaaaaga caagctctct agctactgcg acattaaaga
    39001 ctggaatgta tacaaagtat atactgatgg aggtttctca ggatccaaca ctgacagacc
    39061 agcgctagaa agtcttatca aagacgctaa aaaaagaaaa tttgacacag ttctagtcta
    39121 taagctggac cgtcttagcc gtagtcaaaa agacacgctt cacttgattg aggatgtatt
    39181 catcaagaat gggattgaat ttctgagctt gcaggagaac tttgacacct ctactccttt
    39241 tggtaaggct atgattggac tcttgagcgt ctttgctcag ctagaaaggg agcaaatcaa
    39301 ggaacgcatg caacttggca agctaggacg tgccaaatct ggtaaatcca tgatgtgggc
    39361 taagacatcc tatggttacg attaccacaa agagacaggc acagtgacca tcaatccagc
    39421 tcaggctctg accattaagt ttatctttga gagttacctg agagggagat ctattactaa
    39481 gttgagagat gatctaaatg agaaataccc aaagcatgtg ccttggagct atcgggcggt
    39541 cagaaccata ctcgataacc ctgtctattg tggtttcaat cagtataagg gagaaattta
    39601 tccaggtaat catgagccga ttatttcaaa agaggaatac gataagactc aatctgagct
    39661 aaaaataaga caaagaacag cagcagagaa tgtcaatcct agaccattcc aagctaagta
    39721 cattttatcc ggtatcgccc aatgtggata ttgtggcgct cctttaaaaa ttatgttagg
    39781 cgtaaagagg aaagatggga gcaggttaaa aaaatatgaa tgccatcaaa ggcacccacg
    39841 aacgctgaga ggcgttacta cctacaacga caataaaaag tgtgactcag gattttacta
    39901 caaagacaag ctagaggcct ctgtgctaaa agaaataagc aagctacaag atgacgctga
    39961 ttacctggac aaaatatttt caggagacaa tgctgagacc atagaccgtg agagctataa
    40021 gaaacaaata gaggagctat caaagaaact gagcagactt aacgatctat acatagatga
    40081 ccgcattacc cttgaagaat tacagagcaa gtcagccgaa tttataagca tgagggctac
    40141 tcttgagact gaactggaaa acgatccagc actcaggaag aacaaaagaa aggctgatat
    40201 gaggaaactg ctaaacgctg agaaagtctt ttcaatggac tacgaaagtc aaaaggtgct
    40261 tgttagaagg cttataaaca aggttaaggt gacagctgag gacattgtta tcaattggaa
    40321 aatataaat
//
LOCUS       DAVLCS010000016        39634 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLCS010000016 DAVLCS010000000
VERSION     DAVLCS010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.016"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(293..1390)
                     /locus_tag="VXC78_000968"
     CDS             complement(293..1390)
                     /locus_tag="VXC78_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV0583072.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARESDLPEGIHVLGFTEKGRQHLKYLKGQVSLVSRIGKEPWDV
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
     gene            complement(1400..2146)
                     /locus_tag="VXC78_000969"
     CDS             complement(1400..2146)
                     /locus_tag="VXC78_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0583073.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(2249..2602)
                     /gene="rsfS"
                     /locus_tag="VXC78_000970"
     CDS             complement(2249..2602)
                     /gene="rsfS"
                     /locus_tag="VXC78_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV0583074.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(2615..3115)
                     /locus_tag="VXC78_000971"
     CDS             complement(2615..3115)
                     /locus_tag="VXC78_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0583075.1"
                     /translation="MKMAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKIAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(3116..3709)
                     /gene="yqeK"
                     /locus_tag="VXC78_000972"
     CDS             complement(3116..3709)
                     /gene="yqeK"
                     /locus_tag="VXC78_000972"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV0583076.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPGLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVVYVADYIEHNRSFPGVDVAREVASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(3709..4338)
                     /locus_tag="VXC78_000973"
     CDS             complement(3709..4338)
                     /locus_tag="VXC78_000973"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV0583077.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLVPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(4390..4701)
                     /gene="yhbY"
                     /locus_tag="VXC78_000974"
     CDS             complement(4390..4701)
                     /gene="yhbY"
                     /locus_tag="VXC78_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV0583078.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(4915..6021)
                     /gene="yqeH"
                     /locus_tag="VXC78_000975"
     CDS             complement(4915..6021)
                     /gene="yqeH"
                     /locus_tag="VXC78_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV0583079.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAYEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            complement(6024..6614)
                     /locus_tag="VXC78_000976"
     CDS             complement(6024..6614)
                     /locus_tag="VXC78_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV0583080.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(6566..7474)
                     /locus_tag="VXC78_000977"
     CDS             complement(6566..7474)
                     /locus_tag="VXC78_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0583081.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFV
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(7531..8091)
                     /locus_tag="VXC78_000978"
     CDS             complement(7531..8091)
                     /locus_tag="VXC78_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV0583082.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            8230..9445
                     /gene="sstT"
                     /locus_tag="VXC78_000979"
                     /pseudo
     CDS             8230..9445
                     /gene="sstT"
                     /locus_tag="VXC78_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            9513..10466
                     /locus_tag="VXC78_000980"
     CDS             9513..10466
                     /locus_tag="VXC78_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0583083.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(10564..10641)
                     /locus_tag="VXC78_000981"
                     /pseudo
     CDS             complement(10564..10641)
                     /locus_tag="VXC78_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(10702..10926)
                     /locus_tag="VXC78_000982"
     CDS             complement(10702..10926)
                     /locus_tag="VXC78_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HEV0583084.1"
                     /translation="MIEILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            complement(10931..11110)
                     /gene="asp4"
                     /locus_tag="VXC78_000983"
     CDS             complement(10931..11110)
                     /gene="asp4"
                     /locus_tag="VXC78_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HEV0583085.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(11112..12449)
                     /gene="gtfB"
                     /locus_tag="VXC78_000984"
     CDS             complement(11112..12449)
                     /gene="gtfB"
                     /locus_tag="VXC78_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HEV0583086.1"
                     /translation="MIELYDRYSHESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIAGALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQETMQTVLGG"
     gene            complement(12442..13953)
                     /gene="gtfA"
                     /locus_tag="VXC78_000985"
     CDS             complement(12442..13953)
                     /gene="gtfA"
                     /locus_tag="VXC78_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HEV0583087.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEVQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLRDIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(13965..16337)
                     /gene="secA2"
                     /locus_tag="VXC78_000986"
     CDS             complement(13965..16337)
                     /gene="secA2"
                     /locus_tag="VXC78_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HEV0583088.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(16330..16770)
                     /gene="asp3"
                     /locus_tag="VXC78_000987"
     CDS             complement(16330..16770)
                     /gene="asp3"
                     /locus_tag="VXC78_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HEV0583089.1"
                     /translation="MIITQRQSIHWGEVGGTYMYGTTVSYYPDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKVKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(16767..18302)
                     /gene="asp2"
                     /locus_tag="VXC78_000988"
     CDS             complement(16767..18302)
                     /gene="asp2"
                     /locus_tag="VXC78_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HEV0583090.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKALREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(18286..19866)
                     /gene="asp1"
                     /locus_tag="VXC78_000989"
     CDS             complement(18286..19866)
                     /gene="asp1"
                     /locus_tag="VXC78_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HEV0583091.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFGPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLADVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(19876..21093)
                     /gene="secY2"
                     /locus_tag="VXC78_000990"
     CDS             complement(19876..21093)
                     /gene="secY2"
                     /locus_tag="VXC78_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HEV0583092.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     RMYLTLLIAVIQSLAVSLSLPVQSSYSVILVALMNTLLLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSIVLNIPQDVIETFKLVYIPTGIVVLLVFMTIIFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYSYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMVGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVIMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYRPLI"
     gene            complement(21150..22058)
                     /locus_tag="VXC78_000991"
     CDS             complement(21150..22058)
                     /locus_tag="VXC78_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0583093.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGGAAQAKNMGISVAKGEYITIVDSDDIVKENMI
                     ETLYQQVQEKDADVVIGNYYNYDESDGNFYFYVTGKDFCVEELAIQEIMNRQAGDWKF
                     NSSAFILPTFKLIKKELFNEVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRR
                     SGSIMRTEFDLSWARDIVEVFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQL
                     TDTEEYKDICFRLKLFFDAEQRNGKS"
     gene            complement(22058..23254)
                     /locus_tag="VXC78_000992"
     CDS             complement(22058..23254)
                     /locus_tag="VXC78_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV0583094.1"
                     /translation="MRKSIVLAADNVYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNSGVLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(23263..24483)
                     /locus_tag="VXC78_000993"
     CDS             complement(23263..24483)
                     /locus_tag="VXC78_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HEV0583095.1"
                     /translation="MLQDKKSVVFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(24508..25392)
                     /locus_tag="VXC78_000994"
     CDS             complement(24508..25392)
                     /locus_tag="VXC78_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0583096.1"
                     /translation="MKDLISVIVPVYNVEPFISSCLDSLSKQIYQNFEVLLVNDGSTD
                     NSGAICREYADRDSRFHYFEKENAGVADARNFGIERSKGDYITFVDSDDWVTEEYLSI
                     LIETLKEQHSEIVVSTYSTYNESDGLFYIHVFDSDYYVKNYNSKLLMEELPLLERYDM
                     SFLTSWGILFKRELFQEVQFPFGRVCEDIGTNYKLFMQVEKVTYINKVLYWYRVGKEG
                     LSNSYSPKMMRDDCDFRLERIAVLALKGYDVSKYLDQMKFYLKYRHDIAIQRELKENV
                     ETRHLEMLDYLLNGNKYN"
     gene            complement(25389..27842)
                     /locus_tag="VXC78_000995"
     CDS             complement(25389..27842)
                     /locus_tag="VXC78_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HEV0583097.1"
                     /translation="MIKTIVLAGNRNYTRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIASMLGSEIIDVKLPEQTVFQDWKKQAHISSIAYARYFIPDYIQEDTVLYLD
                     CDLLINDKLDSLFEQDVREHYIAAIRDANGQGFNTGVLLINNEKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELGRAYNLQVGHDIVALYNNWQEHLAF
                     NDKPVVIHFTTYRKPWTTLTANRYRDLWWEFHDLEWNQILQHHLGEFELISPLDKEFS
                     CLTLTNSQDLEGIEELVTALPEVVFHIAAWTDMGDKLKKLAVYNNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEVNLMWGLPIPYQNHDLELANQLKHIVGLESDEKLVVCLPDAFDDRFVFTW
                     WATPFWKEHMNVYMDFYKELCKGSWYGSTFISRPYIDYEDKSKAKGQFEKLKSIWENR
                     DILIVEGITSRSGVGNDLFDKVKSVKRIICPSHNAYSVVDNIQEEIMKHAEGRLILCM
                     LGPTAKVLAYHLSRKGYQVLDIGHIDSEYEWMKMGAKTKVKFSHKHTAEYNFDQDIQF
                     IEDETYNSQILVDLSKREV"
     gene            complement(27852..28862)
                     /locus_tag="VXC78_000996"
     CDS             complement(27852..28862)
                     /locus_tag="VXC78_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0583098.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKRTFFAGSLERFPDLQNWSQDTPLRVFSNKGEAGSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTHQNEGESNQYYTLNISHKVSTYLTAGIPVIVPSNLSTAKFIV
                     DQGLGFVANSLEEVHEIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            complement(28891..29481)
                     /locus_tag="VXC78_000997"
     CDS             complement(28891..29481)
                     /locus_tag="VXC78_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEV0583099.1"
                     /translation="MEHDALDRLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDD
                     SLEVIEGKAIMDREGVEEVRNGNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVL
                     LRASRIVYLNRCVYWYRVGLSDTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHI
                     LIYKNRLQRVVAKLEEQNMQFTEIYRRMMEKLSLLP"
     gene            complement(29489..29767)
                     /locus_tag="VXC78_000998"
     CDS             complement(29489..29767)
                     /locus_tag="VXC78_000998"
                     /inference="COORDINATES: protein motif:HMM:NF012745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0583100.1"
                     /translation="MENELISIVVPIYNVENYLRMCLDSIQNQTYQNFECLLINDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGGVHYFCRL"
     gene            complement(29772..30986)
                     /locus_tag="VXC78_000999"
     CDS             complement(29772..30986)
                     /locus_tag="VXC78_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV0583101.1"
                     /translation="MYRKVIALGADIHYLDKVETVIKSVSVHNHEVKFYVFNDDLPSE
                     WFLLMRNRLKVIGSEIINVKKADHNLRDFHLPNAILSYATFFRYFIADEVLEDRVLYL
                     DSDIIVNANLDELFFLDLQGYAIAAVQDFDQDGWLTTFNSGMLLIDAKKWREKKSTQN
                     LLELTAQHHEHVYGDQGVLNIYFGDQWLHLDKEYNFMVGLDQFLHLKGNADWYQSNYY
                     GNYEPKIVHYTTEFKPWTHLTLTRFRKLWWFYYGLNWNDVLLSSDIVKRSFKELVGVP
                     LYHTCIFTNSAAMESLEYLLSELPEVHFTILAHTNFAPSVVDLQRYLNLSLFPNFNSF
                     NMKETLDKMDFYLDINHEGEIVNIIEEVCRRNKPIFSFDNTSHDSKGRSRIFSATEPD
                     KMVDAIRKFLGE"
     gene            complement(31343..32221)
                     /locus_tag="VXC78_001000"
     CDS             complement(31343..32221)
                     /locus_tag="VXC78_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HEV0583102.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLSNICFHIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVACRNFENFHVSSGKLILNNGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLFVKMRV"
     gene            complement(32218..33618)
                     /locus_tag="VXC78_001001"
     CDS             complement(32218..33618)
                     /locus_tag="VXC78_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000543101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV0583103.1"
                     /translation="MHALVDAMSERITLLANMGYPLEKHLAIYRQMLEFSLANGQASG
                     LSDTATYKEFEMKKRLLNQLTVQESSEKKAIVLAANYAYVDQVLTTIRSICYHNRSLR
                     FYLIHSDFPNEWIKQLNKRLEKFDSEIINCRVTSEQISCYKSDISYTVFLRYFIADFV
                     QEDKALYLDCDLVVTKNLDDLFATDLQDYPLAAVRDFGGRAYFGQEIFNAGVLLVNNA
                     FWKKENMTQKLIDLTNEWHDKVDQADQSILNMLFEHKWLELDFDYNHIVIHKQFADYQ
                     LPEGQDYPAIIHYLSHRKPWKDLAAQTYREVWWYYHGLEWTELGQNHHLHPLQRSHIY
                     PIKEPFTCLIYTASDHIEQIETLVQSLPDIQFKIAARVIVSDRLAQMTIYPNVTIFNG
                     IHYLVDVDNELVETSQVLLDINHGEKTEEILDQFANLGKPILSFENTKTYEVGQEAYA
                     VDQVQAMIEKLREISK"
     gene            complement(33665..39592)
                     /locus_tag="VXC78_001002"
     CDS             complement(33665..39592)
                     /locus_tag="VXC78_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HEV0583104.1"
                     /translation="MFFRRQKGEYRETDRVTRFKLIKSGKHWLRASTSLFGLFKVMRG
                     GVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVISGTVATQTKVFTNESAVLEKTV
                     EKTDALATNGTVVLGTISTSNSASSTSLSASESASTSASESASTSASTSASTSASESA
                     STSASTSISASSTVVGSQTAAATEATAKKVEEDRKKPASDYVASVTNVNLQSYAKRRK
                     RSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIAKSETKVYTGKGVDSVYNVPIY
                     YRLTVTNDGLKLTFTYTVTYVDPKTKTLGNISKKMSNGYSIYNTGTSIQTMLTLGSGL
                     GTPSDVKNSITNKNGGQVQYYNTSTMTKRGSRYTWGNGAQMNGWQAKREYGLTSSWTV
                     PITGTDTSFTFTPYAAKTDNIRTNYFNGRGKVVESSTTSQSLSQSKSLSVSASQSASA
                     SASTSASASASTSASASASTSASASTSASASASTSASASASTSASESASTSASASAST
                     SASASASTSASASASTSASASASTSASASASTSASVSASTSASASASTSASASASTSA
                     SESASTSASESASTSASASASTSASASASTSASASASTSASESASTSASASASTSASA
                     SASTSASASASTSASESASTSASASASTSASASASTSASASASISASESASTSASASA
                     STSASASASTSASESASTSASASASTSASASASISASASASTSASESASTSASASAST
                     SASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTST
                     SVSASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASA
                     SASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASA
                     STSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASAST
                     SASASASTSASESASTSASASASTSASESASTSASASASTSASVSASTSASASASTSA
                     SASASTSASESASTSASASASTSASASASTSASASASTSASTSASTSASASASTSASA
                     SASTSASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASA
                     STSASASASTSASASASTSASASASTSASALASTSASASASTSASASASTSASESAST
                     SASASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSA
                     SASASTSASESASTSASASASTSTSASESASTSASASASTSASASASTSASASASTSA
                     SASASTSASTSASTSASESASTSASASASTSASASASASTSASVSASTSASESASTSA
                     SASASTSASVSASTSASESASTSASASASTSASASASTSASSSASTSASESASTSASA
                     SASTSASASASTSASASASTSASASASTSASASASTSASASASISASESASTSASASA
                     STSASASASTSASASASTSASASASTSASASASISASASASTSASASASTSASASAST
                     SASESASTSASASASTSASESASTSASASASTSASASASTSASASASTSASESASTSA
                     SASASTSASASASTSASSSASTSASASASTSASESASTSASESASTSASSSASTSASA
                     SASTSASASASTSASASASTSASTSASTSASASASTSASASASTSASASASTSASASA
                     STSASASASTSASASASTSASESASTSASASASTSASVSASTSASASASTSASASAST
                     SASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSA
                     SESASTSASASASTSASASASTSASESASTSASASASTSASASASTSASESASTSASA
                     SASTSASASASTSASASASESASTSASASTSAGKSRQQLPNTGTEASKSSVLLGALAA
                     VTGLGLFAKRRKRDDEE"
BASE COUNT        11626 a         8691 c         7301 g        12016 t
ORIGIN      
        1 atcttctttt ttattacata atcttaaaca aaagtttatc atggtttata aatataaaaa
       61 tttatttgtc ttttatattc aatttatgat ttttaatata accagttctc ttcattatac
      121 cacaaaataa caagcataaa gcggattcaa agataaagat taaggttcat atactaattt
      181 tctttattga ctttttgtct tctgtattag ggagtttatc attttccaaa aactttatct
      241 tcaatttgtt agctaaaatt tctacaataa aaaagcctac ctttcagtag acttagtttg
      301 tttctattct aatcggcact ctgccaaaat tctgttctgc tatacttgga tttcccaatt
      361 ggtaaatctg gtctgccttt tgagtcatga catcccaagg ttccttgcca attctgctga
      421 ctagactgac ctgccctttc agatatttaa gatgttgcct gcctttttcg gtaaagccaa
      481 ggacatgaat cccttctggc aagtcacttt ctctagcctg caccaagata taggtcaaga
      541 ggcgtctgac acgcgccttg gtgtaacgtt tggtggtcac taactcgacc aattcttcca
      601 cagactgggc tgttttaata gcttctttaa tgcgcacagc catttcttga ttgacctgat
      661 agatggtggt taggtcggga tttgacaaga tttgatagcg gagcaaggga aaatagtctt
      721 cccagatcac cttactggcc tgctcaaata gggcaacaga aggcataaaa cgttctaaga
      781 aatcttggtc cttctgatgt tgacggaggg ctgtcgccga ggcaaagtcc acatctttat
      841 tcacagaatg gtaacctgcc ccctgacgct gaatcggatg cagcttgata tttcgtcctg
      901 caaccgcctt tgcataggcc agagcaagaa catgattggg ggtattacct gaaaaatcaa
      961 gaccagcaaa ttccttccac atagcttggg ttttctgggg ataggaaagg gaatcaggca
     1021 gattttccac aaatttctcc atctcagcac ctttctctgt gtataagtca gcgattttct
     1081 gataatctcg aacttcctct gtcccaaaaa ctagactatc aatgcccaag cgatccaaga
     1141 tatccacagc tccttgacca aagaaatcag ctgcctgaac actgactaaa aagggcaatt
     1201 ccactaccaa gtctgcgcca ttttccagcg ccatctgggc ccttgtccac ttatccacaa
     1261 tagcaggctc tccacgctgc atgaaattcc ctgacatggc aacaattttc agtccctctg
     1321 cctgatccag caggtattta tggccattat gaaaaggatt gaactccgcg ataatacctg
     1381 tgatggtcat gctaatctcc tacttctgcg ccacaaaaaa ccaacgggtg ctagtttctg
     1441 ttggctcctt atcctcaaag tctgcataga gtttgaagga cttgaatcca gcctgttcca
     1501 gcaagatatc ataggtcaag atctcatagg tcctctcctc atgtacttca tcgtggcgac
     1561 taaaggaacc gtcagcctcc ttgataaaga aagtcagctc atgcacgatg gagtgaggaa
     1621 cttcgtcctc atatgtatcc caaagcatgg caaaatcttc cgcattttca tggtaggaat
     1681 agccagggaa tacttcatct gtctggtagg tcgagtgcac gtcaaagatg aaaactccct
     1741 cttcattcag cgcattgtac acgtccttaa agacgtcccc tacttccacc tcatcctgca
     1801 tatagcagat agagtccgaa taacacgtga caaaatcgta tttccctgcc ttggacaaat
     1861 ttagcatatt accttctata aaagcaatct tttgcttggc tgaagttgct ctcttctccg
     1921 caatcttcaa catatccgca ctcaagtcaa gtccagtcac atcaaaacca gcctgagaga
     1981 agcgcactga ttgaattcct gtcccacaag ccaattccaa gagtttcttt ctctccttgg
     2041 tcttaggcaa atgacgcaga gaaaaattcg tccatttgtc gtataaacta tcgtccatga
     2101 ccgcatcata gacagccgca aaggtttcat aagtcgccat aatcatgata ctaagagctc
     2161 catggtaaac accactagcc ctttaccttt ctatcaattt ttctaaaata agcaaagaaa
     2221 cccagttgac tacaactgag ttcatcttct aagcaagagc ttctgaaata tctactgaat
     2281 tcgcctcatg ccatagcttc tctagattat aatgggcacg catttcttct gaaaagatat
     2341 gcacgacaac agcaccgagg tccagtaaga cccagcctcc agctgcatcg ccttcgacat
     2401 ggctaccttt aaagcctgct tgagctactt tttcacggat attagctgcg atagcgtcca
     2461 gctgacggct attcattgag ctagtgatga caaagtagtc cgtcacacta gtcaaatctt
     2521 gtacatcaag tgcgaggata tcctccgcac gtttctcatc agccgctttc acgactagtt
     2581 ctagtaattc tttttcgttc atttaatcct ctttttagaa aatatgtttg taatctagga
     2641 catctgcaaa gcgctcctcc caaatgtcct cataaaattc attaatcgtt tctgctggaa
     2701 tgtcatcccc atcaaaggtt gtgacagcac cttctggaac aataagctga tagccatatt
     2761 caaaggcaat cttgacagag gtatccacac aatattctgt ctgcatacca cataaaacta
     2821 atttttcaat cccctgctta tccaagtatt cttttaagcc agtttctttg aaaatactgt
     2881 tatatttctt ctgaaagacc ttttcagcag gttttcgatt taaaagcgca gataactgcc
     2941 aatcttctga tgtttgagct tcagagttct caatatgttg aacatagata atttcaatat
     3001 tcttgcttct agcctggttt tgtaaataag aaattttttc caatagactt tttgtctgga
     3061 acccagtttc tactaaaaca ttctgaacat caatgattat aaaagccatc ttcatttagt
     3121 tctctttcaa atagtgcaca aaggcgttat aggtttcaag ggtttgggga tagatgggga
     3181 atccctgatg agctagatac tccacggtac gagctgtttc gtaggccacc gccttattga
     3241 gcgatagact tgcaacctca cgcgccacat ctactccagg aaaggatcga ttgtgctcga
     3301 tatagtctgc tacatagaca accttatcta ggtctgtcat ctgaccagca ccgactgtat
     3361 ggacttcaat ggctcgcagg atttctgaat catgcaaatc caaatcttcc tgaattttgt
     3421 aaattccgac cataccatgc cagacattat tgccccagtt tttgaggcca gggtctagct
     3481 ggtaacggtc aatcaagtct agaaattcct gatctgacaa ctttttagca tagtcatgaa
     3541 gaagacctgc tagacttgct ttctcaacat ctacaccaaa gcgctgagct aattccatag
     3601 cggcacgctc cacacctaga caatgggtta gacgtttctc aggtagaagc tctgccattt
     3661 tttccaacaa ggcctcacgg gagcagttga tatagtcttg ataggacatc agtagagccc
     3721 ctccttctcg atgtagtcta gcactggctg aggtaggaga aagttgggtt tccgaccttg
     3781 ggcaatgaag tcccgcacca tgctggacga gatatccatg agcggtacgt ccacccagat
     3841 aactggatag gaagtccctg ccttgtagcg tggacgctga acccccacaa actgaaccat
     3901 gtcaaccagt tcatcaattc ggtaccactt aggcagatag tcaaccatgt cggcgccgat
     3961 gataaagtaa taatccgtat ctggatgttg ctctgtcaag attttcatgg tgtcgtaggt
     4021 gtaggaaata cccttgcgct ccaactcaat ggtttcaatg actaggccgt caatcccctc
     4081 aattgccaac tcaagcatct tgagacgatg gtgttcaggg atggtttcct ttttatcaac
     4141 gtgaggaggt tggtattcag gcacgagaag aacttgatcc agtcccaact gttgccgtac
     4201 ttgatccgca acaatgagat gggcattgtg aacagggtta aaattccccc ctaaaatccc
     4261 aacttgtttg cgttttttct ccttgatttc tggctccaac tctaccttgg taaagggagt
     4321 caatagttcg attgtcatag gctagtcccc tttatttctc tataaaaaca gttatttgga
     4381 gtttcggtct tagatttctt tgactttctt agaaatcttg cgattttctt tcttgctaga
     4441 ttgtttaaac aaaatcaaga tgcgtcctat tttttggact gtatccacac cgatttcttc
     4501 ttccaaaatt tcagctactt cgtggatgtt ttcatctgtg ttttgtaaga gagtaacctt
     4561 gattaattca cgcgcatcaa gagcttgacg gacgctggtt ttgatttggt cgttgagtcc
     4621 atttttcccg atttggatga taggtttgag ggtgtgtgcc tggctgttga ggaaggcacg
     4681 ttgttttgat gttaatgaca taattttctt ccttgttttt tgatagttat tttaggtggt
     4741 gagggacggt cggaactaat tttccaaaga tttcatcttt gaaaaatgga tttcctgacc
     4801 tcacaattga gccttggtct caattgtgcc ccttgccaat ctacagattg gcaatcacac
     4861 cacggcaata actatcgcta tatgagctca ctttgttcgc tcagcgattt tgttttaaat
     4921 aattgctttt cgtgtaacga cggcgacgcc ttctggtgcc cagacggcga cttttgctgt
     4981 gcctgttaca cgaatccagc ctaggcctga gatgactagg tctgtcttat ctttaatggt
     5041 aaagacatgc tggactagcc ttgggaaatc ttctttttcc ttgctatttg gtggtgtcag
     5101 aagagttccc aggtgcttat cgtagaaagc actagctcct tcaagcttgc tacgatggag
     5161 tttgagttca ttatcaaaga aagcagtaaa tccttgcttt tctcctgcta taaagtcaaa
     5221 gcgtcccaaa ccacctaaaa atagggtttg ctcaggatta agctgatagg tcttaggctt
     5281 gatttccttt ttaggactga catacttgag gtttttggcc gtcaagtagt gagccatctg
     5341 gtggcggtgg ataattcccg gcgtatcgta aatataagat ccgtcgtcaa gcggaatctc
     5401 tattttgtcc aaggttgtcc ctgggaagcg tgaagtagtg atgacattct gatcacccgt
     5461 gatttcttgg ataatagcat tgattagagt tgattttcca acgttggtca caccgaccac
     5521 atagacatcg cggcccttac ggtagtgttc aatcttgtca atgacttcct taatggcatg
     5581 tttattttgt gctgaagtta ggaccacatc gactggacga agaccttctt cataggcacg
     5641 tttcatgagc cactggctaa tcttaccaga cttaactgac ttaggaagga tatctttttt
     5701 atttcctacc aagaggacat cattgcccga gacgaaacgt ggtaaacctg ggatgacaga
     5761 tccattaaaa tcaaagatat caatgacatt gaccactaaa gcatcactgt ctcccacctc
     5821 gtgcaagagc ttgaggaaat catcgttcgt caactggaca tctgtgattt cattgtagtg
     5881 gcggagacgg aaacagcgtt ggcaatagac ttcgccagtc tccaaacctt tttcaagtgc
     5941 cgactggggg gtaaaaccaa gaccagcttt atctgtcgtc tgaatggttg ctccacaacc
     6001 aatacagaga atttcttcca tagttaaatt ccttttttat atgtaatcgg tccgtacttt
     6061 tcagtgattt ttctcataac acgacgctca cgagttcggt taatctgcgt tttgattgag
     6121 tcatgttgga ccaagggttt gactaaaatt gaccgaatcc ctgcacggtg ggctgctcgt
     6181 atatctgtca tgagctggtc gccaaccatg actacttcct ttttgtcata gtggaattcc
     6241 ttcatggcac ggtcaatacc aaatgtgaag ggcttcaagg cccagtaaac gtaatcaatc
     6301 ccaaatttct caactgctcg ttgaacgcgt tttttggtgt tatttgacac tacgataatg
     6361 ccaatacccg cgtcccgaag gtcatgtagc cattgcttca tctctggcgt tccatcaggg
     6421 ttgttccaag caatgagggt attatccaaa tcgaccaaaa cagccttgat tccctgcgcc
     6481 tgcaggcttg ggactgtcag atcatagact gcttccacag caaaatctgg tatataattt
     6541 tcaatcgcca ttctggctcc ttttcttaac tttttttcgc aattttcctt agtaacaagg
     6601 ataaaacaat ccacaaacct gcactagcca aactgatata gagccaagca tggggctcat
     6661 ctgttaaagg taagggaaca ttcattccga aaaagcctgt cacgactgcc aaaacagcta
     6721 gcaagactga aatgatagtc aaggttgtca aattgtcatt cagattattg tttagaatat
     6781 tgttgtaaga ggctgaaagc tgctgtaaaa tctgagagat taggtctgtc atggatacca
     6841 gctgatgagc ctcaatcatg gcatcatcaa actgttctct ctcaatctca tcaaaactac
     6901 gatacaaggc atgaccttga atatgctcta acaaaatccg attttgtttg gcagctgccg
     6961 tcagataaac cataccagtc tccaaatcag acaggacaaa gaggtttttc ttggtagttc
     7021 gctggcgcaa gaggtcattg acctcatccc tactcttgtc catctgctca atgacaggat
     7081 agtaggcatt gctgataatt tccagactgg caaagagaaa cttataaatc gaaagcgtgt
     7141 catggctctc cagataacga gtcatctgtt caatgacata ggcgttcttg gtattactaa
     7201 tggtaatcag gcgacgatgc tcgacaataa aggtcatggg aaaagtctca tagtaggcct
     7261 tgtccttttt tacatctagg acattataga taaaggtaac cgtcccactt tcacggtggt
     7321 agtccatgtg ggcgcgctcg tttctatcca gtgcgtattc aatggtttcc ttgtccaaac
     7381 cgtaaatttc agaaaggtct tctagtttat tcaactttcc taggtctagg tctatccagg
     7441 tacaaccatt gcccaactgc ttttctaaaa ccatcttttc tccttattaa actccctcta
     7501 ttgtaccaca aattacttaa aataacaggt ctagtctgtg cgtgagaaat tgctaacaac
     7561 tgtgatattt cggttaggga caaagtgaag ggcttgctcc tcgctacgaa gctgtgtcgt
     7621 acgaattccc acactgacaa ccttacccga tacagtaatc ggtccatttg tcagaacgac
     7681 ctcatctccc acatccagtt gacgttcaaa gaggatgaaa aagccattga tgacatcaga
     7741 cagaaagcct tgggctccca taccaatcgc taccccagca ataccagctc cagccagcaa
     7801 actagaaact ggcaaaccta aaatcgacaa aatgcagtag agtaaaaaga aatatagcgt
     7861 ataattaaac acattttcta gtaaacgtga gatggttttt tggcgtccga catcatgacg
     7921 agacattttt agagaaggtt tgacaattct ctgcaccatg gtatgaagca tttttttagc
     7981 aatataaaat acaatcaaaa gcagtaaaag agaaatgacc ttggttagaa tattctcgat
     8041 aatggttgtc acatctagct tttcaatata agcctgaata aatttttgca tataaaactc
     8101 ctttatttca ttataccata ttttcatcag tctcattctc cataaatatt caaaaaatag
     8161 acagaaaatt cttgattttg tctatcattt atactataat cataatcact acacaaaaag
     8221 gagattatta tgaaaagaat cattcatgct tggaataagg caagccttgt caagcgtatc
     8281 ttgattggta tgctttgtgg ggaatcctag gactgaccct tcctaatctc tcagggattg
     8341 ggctactcga ggatttattc gttggaggtc taaaagctgt tgctcctatc ctagtctttg
     8401 ctctcgttgc caatgccctt tcccaacatc aaaagggaca agatagcaat atgaaaactg
     8461 ttgttttctt gtatatccta tgatagggac tttcgccgct gctcttgtag ctgtactagc
     8521 aagtttcatc gtccctattg aaattaccct aaatagtgcc aatactgaaa ttgcaccacc
     8581 agatgggatt gggcaggtcc tcagcaacct cttgctcaaa ctggttgaca acccagtcaa
     8641 cgccctgctt actgctaact atattggaat cttatcttgg gcagtcattt ttggaatcgc
     8701 tatgagagaa gccagtaaaa atagtaaaga attgctaaaa actatcgctg acgtgacttc
     8761 taaaattgtc gaatggatca tcaatctggc tccatttgga atccttggtc ttgtttttaa
     8821 aaccatttct gacaagggag tcggaagcct tgccaactac ggtattttat tggttccatt
     8881 agtaacgact atgctttttg ttgcccctgt ggtcaaccct ttgattgcct tcttctttat
     8941 gagtatgaga cgcaatcctt accctctagt ttggaactgc ctccgtgtca gcggtgtgac
     9001 agcctttttc actcgtagtt ctgcgactaa cattcctgtc aacatgaaac tctgccatga
     9061 ccttggactc aacccagata cctattctgt ttctatccca ctcggttcta ctatcaatat
     9121 ggctggagta gcgattacca ttaacgtttt gacccttgtt acagttaaca ctcttggaat
     9181 tcctgttgac tttgccacag cctttgtcct cagtgtggta gcagctatct cagcctgtgg
     9241 tgcttcaggt attgccggag gttccctcct tcttatccca gttgcttgta gccttttcgg
     9301 tatttctaac gatattgcca tacaagttgt tggggttggt tttgtgattg gtgtcatcca
     9361 agactcatgt gaaacagccc ttaactcttc tacagatgtc ctctttaccg ccgttgccga
     9421 atacgcagca acccgtaaaa aataactcat caaggcaagc ctgctcatgt cttgtctttt
     9481 acgcttttat tctaacttat taggaaattc ttatgtctat tagccaacgt acgaccaagc
     9541 tcatcttagc tacctgtctt gcctgcctgc ttgcttattt tctcaatctt tcgtcagcag
     9601 tttcggctgg aattatcgct ctcttgagcc tatctgatac gcgtagaagt actttaaaac
     9661 tggctcgcaa tcgtcttttt tctatgcttc tagctctggc tatcggtgtt ctagcttttc
     9721 acttgagcgg atttcatatc tggagtctcg gcctctatct ggccttctac gttcctttag
     9781 cctacaagat gggctgggaa attggcatca caccaagcac ggttttggtt agccatctct
     9841 tggttcaaga gtcaacctct ccagacctcc tagtcaacga attccttctc tttgctattg
     9901 gtacaggatt tgccttgctt gttaatctct atatgccttc acgagaagag gaaatccagc
     9961 actaccacac gctggtggaa gaaaagttaa aagatatcct ccagcgcttc aaatactatt
    10021 tatccagagg agacggacgc aaccgagcac agctggtagc agaattagac acgcttttga
    10081 aagaagccct cagactggtc tatttggatc actctgacca cctctttcac cagaccgact
    10141 accatatcca ctactttgag atgagacaac gacaaagtcg tatcctgaga aacatggccc
    10201 aacagattaa cacttgtcac cttgccgcca gtgaaagcct gatcttagcg caactctttt
    10261 caaaaattgc aggtcaactg agccagacca atcctgcttc tgatttgcta gatgaaattg
    10321 aacgttatct ggaagtcttc cggaaccgca gtctgcccaa gacaagagaa gaatttgaaa
    10381 cccgcgccac ccttcttcaa ctcctacgtg aagccaaaac cttcatccaa gtaaaagttg
    10441 atttttacca aaaatataga cagtaatact cttcaaacta cgtcagcttc accttgccgt
    10501 atatatgtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt ttgagctgac
    10561 ttcgtcagtt ctatctacaa cctcaaaacg gtgttttgag cagcctgcgg ctagcttcct
    10621 agtttgctct ttgattttca ttgagtataa aaaagaaaac ttcagaccaa tccacaaaag
    10681 gtgaatatct gaagttttct tttatttata agtaatcacc ataaaggtta atagtagaac
    10741 aaataaagcc aaactcacca ataaagtgag caccttgacc aaggtgttgc tctgccagta
    10801 gcttggttta ccaatattac tagtggcatc catggaaaat agttgatttt gacggggttg
    10861 tatagttacc aatacaatca aagcaagaga taggataata gctaaaacaa ttagtatttc
    10921 aatcatagat ctacctcaaa attcccagca aagtaaagag caaaccaatc agaatcatca
    10981 aacccagtaa aagtgaaaaa gtcttactaa tcttttcccc tcgggtttct ttttccttct
    11041 tgatgggttt ttgtttcaac tcttccatgc ggccttcaac gtctttgtaa aataaatctt
    11101 cctctgacat gttagcctcc taaaacagtt tgcatggttt cctgatatct caccaagtca
    11161 acataatttg catgttggcc ttgtttgcca agtgcctgac gcatttgatc aacatctgaa
    11221 agggccaatt taatggtctc aaccaaagca gcaacttcac tactttcaaa tagatggtct
    11281 ggagcgatat aaagtctatt gtgcaccgtc tgattaaagc caagaatcaa gagattgtgc
    11341 tcaaaggcct gacgcactgc ctgtagtaac tcattactgt ggtttatatc caagtaaata
    11401 tccgacagtt gatacagctc ctgaatcttc tgtggactag cattctggta aaggaccaca
    11461 ttaggatagc gaagcatgtc taagagctta gaagacatct ctgtcaccgc tgcaatacgg
    11521 aaagtgacat caggcaaggc tcctgcgatt gcttctactt gctcaatctg atctgaattg
    11581 gtcaagatta aggcatctcg tcttaggaaa ttatcacgtt tgaactggta atgataaccc
    11641 aagtgcacaa actgatcatg gtatttctcg tcagttaact ctaaagcgcg ctcataagtc
    11701 gccttatttg gaatgatgat cttcttagta cgcacattat cactttccaa aatcaactgc
    11761 atattacctg gaatggcatc atagagaggt tcctgccata ccaagacatc cgagccagat
    11821 ttatctggat gatggaagga aaccaagaaa ggagtcgcta gagtattaaa gataagctga
    11881 ctggtatcta tttccaaatc ttgcaaaaag aaggtgataa attcaacttt atttgcaaag
    11941 taacgcatgg actgaccagg caaagtcaat aagatatcac ccgtcacatg gttttccagt
    12001 aaaacttgtt ggccattgac atcttggtaa actgtcataa tcggctcgct atctgcgcta
    12061 taagtggttt tagcaaagca agcaccaaag cgattgtagt ggtcaacctg acgtactcga
    12121 ccttctaggt ctttccagtc tacctgttta accaagcgag cctgcattcc atcaacataa
    12181 tgaatgacag ccctctcctg cgtcacatct tcaatacaag cagactgatt atctcctaaa
    12241 atttcccaaa aatctgaaac gggaacttgg ttaaaataga gaggttttcc atcctcgtaa
    12301 cctagataat aggtaaaagg agaaagcaga ccatcaggca gaaaaccatc tgcatcgatg
    12361 accactccaa gttgagaaag accagtagcg actagacttt catgtaaatc tcgactttca
    12421 tgactataac gatcataaag ttcaatcatg gagcacctcc tctactgttt tcttccactt
    12481 ttctaaaatt tctttggtca agaagccttc tgcaatttgg taagaatagg cacgcatagc
    12541 ttccaaacga ttttcttgat acaattgaca aatcttagcg gcataagctt gcttgatttg
    12601 gtcttctaca tggtcagatg aacttggaat caaataacca ttttgcccat cctctataaa
    12661 ggtctgatta ccataaggca catcaaaacc aattagaggt agacctgaac caatagcttc
    12721 catcaaggtc agaccaaatc cttcgctggt agaagccgtt aagtagacct catactggct
    12781 ataaatctgc gaaagttccg catgcccctt gagttggata tagtcctctg cctgatgatt
    12841 tgcaataatg tctctaagca gagaatcttc tccaccacta ccatagatat caaaggttag
    12901 ttccggtaac tccttatgag cttcaatcac agctttcaca agccaatcaa tgtgcttttc
    12961 tttggcaaga cgtgaagccg taatcaatga aaatggtttg cgcccttgac ttgaatctgt
    13021 caaggaatca atactgccta caggaatggt aacaatcttt ggctgatgct gagtatattt
    13081 ggcaaattgc tcttgtagaa cttcattttg tctatcagta gacacgataa agaagtcaac
    13141 cttatctgca ttggtaaact gatagtcata atagttattc caaaggatgt agtcctcatt
    13201 tgtagcattt tcactataat gctccgcatg aacaactacc gctaaatgtg ctgtctgtac
    13261 ttcctcaaac acaacctgac caatgcctgt ctccctatcg agaatgacca aatcagactt
    13321 attcaaattc aaagatttca taaaggcacg cacaaaagct tgctttccat agaaaatctt
    13381 atccttgaaa tgataaactt cttccttccc ttgattcatc aagatatcat agactggagt
    13441 cccgtcttca ttataaaaag ttcgttggta taagactgca acattgtcct tgggagcaaa
    13501 atactcgcta caataacgcg tataagaaaa gtaatccttc cgaatcaggt ttcccttaaa
    13561 aacatactcg gcatgttgaa ccaagtcctt gttctcatca accaaataac aggttacaaa
    13621 cttatcttgg tcaaaaaaga atacacgtaa aaccttgcca tttttttctc tgtgactttc
    13681 ttcaccacca aagtaagcca agacatcatc cactgtcacg ctagtaggtg caattttgat
    13741 atctgtgaaa tgattataaa gccagataac ctgattatca tcaaaaccaa tattggctgt
    13801 taagtgctga atattatcgg ctaaaatcat atctgtaaag ataaacttag aggacagatt
    13861 taatttccga aaaacaccag cacgataggc ttgagcgtat tcaacaccgc tactagccca
    13921 accaattcct aaatttatat tgtaaattgt catattttct cctcttatgg aaaatgagtc
    13981 acgatttcac cttttggagt gacctcaacc agccccatca ggagattacg caccatatcc
    14041 gcacggattt gttctttcat agcttcaaag cccgcgtagg cttcttgata gtactctacg
    14101 attggatttt tctgactagc agattgacca ccgatagcca tggatagctg ttgtagatag
    14161 tctacctgct ctacccagtt gtcatcaatg gctttaagca gtgaaagtcg taaaaactgt
    14221 tcatataagt catgttgatt aagtaattct ttcttttcag aaagttcttt atcaatcacc
    14281 tgcttcataa agctacgaac tgcagttttg tcagttacat ctatataatc tggaacctct
    14341 ttaacatgaa aactaatatt ggtcacaata aagtgaaaca ataattcacg actagcatag
    14401 tgatcagccg ctacctcttc tgtatatctc tcaatgatat ccacaacaac atcctctaag
    14461 tcacgagaac catctattag acgatttctc tctttataga ctatatcccg ttgaatattc
    14521 atactttcag catattctag agtctgacga cgtgccgaac ggccagcact atcactggca
    14581 tgctgagcct tttcgactag tttccggtat ttacgacctt tcaatacttc cggttgagtc
    14641 atatcttgaa cctgatagtc tttgtacttt ttatgcaccc aagatggacc aaatttcttg
    14701 ataacatcat cctctaagga tacaaaaaat ttactcatac caggatctcc ctgacgacca
    14761 gaacggccac gaatttgtag gtcgatccgc tgactttcca tccgctcagt cccaataaca
    14821 atcaagcccc caagctctgc gactccttta ccaagcttga tatccgtacc acgtcctgcc
    14881 atagaggtag ccactgtcac agcccccatc tgacctgact cggagataat ctgagcctca
    14941 cgcgccgcat tattagcatt taggacatta tgggcaatcc cttcacgaaa caagagagac
    15001 gaatagagtt gagacatttc aactgagcct acaaaaacga gtaagggatt tcccttagca
    15061 tggtattgct tgatgtactc caaggatgca tacacttttt caggtaaagt gatatataga
    15121 ttatctggat agtcaatccg ttgtctcgga cgattggttg gaatgcgtac tacagacata
    15181 ttgtaagttt caataaactc tttttccgcg accttacctg tccctgtcat accagatatc
    15241 ttattaaaca tcttaaaaag actctgatag gtgatcgagg ccatagcccg cgtctcagga
    15301 gataatttga catgttcctt ggcttcaata gcctgatgga gacctccttg aagtttagtc
    15361 atttccatta gacgccctgt tcccttatca accagtacca tctcatttcc acgaatgata
    15421 tagtccttat ctttagtaaa gagcttatga gctcgaatcg cataaaccaa atgacgagca
    15481 aaagacgcat gctcttcctt gtataaatta tcaatcccta ggaaattctc agcagacttg
    15541 gcccccttag tagtgagcca aacctcctct ttctcctctt taaagatata atcctctcct
    15601 tcgaccaagg ttgttacaag tgtatcaatg atcgcatagt aattagactg aacacgagga
    15661 gaacccgcaa taatcagagg agtttgtgca ctatcaagca agatatcatc aatttcatca
    15721 ataatcacat agttaaacgg tcgtaaaaac ttaccttctt cattcgaggc taggttatca
    15781 tttagataat caaaacctaa attactattg gttgtgtaga tgatatccga agcatagata
    15841 agcttctttt cttcagcttt catctccttc tttggatctt ccgtaaatgg tacaccaatg
    15901 gtcaatccta gaaaacgata aacttgaccc atttcctcgg catcacgctt tgataaatac
    15961 tcattaggag tcacaaccat cactccttct cctgaaaaag cgttcaaata gacaggcatg
    16021 gtagctgtca aggtcttacc ttcccccgta ttcatctcag caacatttcc atagtgcatg
    16081 acaatagctc ccatgacttg aacatcataa ggaaacatcc ctaaaatccg cttatctgct
    16141 tcacgcacca cagcaaaagc ttcaaccaaa atatcgtcta gactttctcc ctcggaaaga
    16201 cgctgacgaa actctactgt tttagctact aattcttgat ccgaaagaga ggacatcttg
    16261 cctttcaggg cattaatctg ctttaaaatc tttttcactt tcctaagctg gaaatcttga
    16321 cctaaacgtc taaacacttc tgatctcctt gatagaaaaa tgataaaaag ttaaggactc
    16381 aaatccagca cttaaaagag aaacttgata agtataacta tcttctggat aagtaaatat
    16441 gaaatctttc actttttcta cctttttttc taaaatatca ccatagcggt caaaaaaagt
    16501 tatcttggta taaactccat tttcaggctg acaatcaaaa accagtgata gttgatactc
    16561 ctgctttctt tttaataagg gaagctgagg ttgggttcgt gcagcctggt aattgacact
    16621 agaaaaccaa gtctttagaa tctcaccaga tggcaataga ggattataca gacgaacact
    16681 tttgtcaggg taataagata cagttgttcc atacatataa gtcccaccaa cttctcccca
    16741 atgaatagac tgtctctgtg taataatcat cttttctccc ttccaaaacc agtctctaag
    16801 accattctat aaaagtgcaa aaaccaagaa atattggtat ctgtatcatc attatgtcgt
    16861 ccagcagttc ctttagataa aatcttcgca cctgtattac acagataaga cactaattgt
    16921 tcataggctt gtggatccat ttcttcatct ttcatatagg ataaaccaaa ggttgtcttt
    16981 gaaaaatttg cttgtttaaa aattttccaa aaacgctgat ccaactccgt catatcttga
    17041 gaacttgtcc cacctgtatg atgaattaaa caatcaaaag ctaagttaga gacacccggt
    17101 gcgtccaaac gtccacgact agctatagtt cctaaattag ccaagggctt accaactatg
    17161 atggcatggg gttcaaaaga agcaccataa tagagagccg gaaacgttcc catagaaaga
    17221 cctgataaaa tcaaatcctt atgatcaaag cctaaataat caagatagtg agtgatcgta
    17281 tcctttactt ttccctctag ctcatccgtt ccgagataaa aagctccccc ctctaaacgt
    17341 ggatcagaaa ataaaatgaa gggacatcca agagtcttca tcataaagta accctcgaat
    17401 ccttctgcag gtcgataacc tgcaaaatag acagtcaaag gcggtttaaa atcacctgga
    17461 tggaagaaat agtttatttc atcacgcttg gaatcatgta ggatatttcc accaagtaca
    17521 aacttaccaa attgttttcg actccatcgt tggtgaagat tacctagttt gatagttcca
    17581 cgacctcttg cttcaacaga tatcgagaga aagtagtctc cgtctcgact atccataaaa
    17641 agtgcttgct ccaagtcttt ttcagatact attacttctt caaagaaatc atcaacagac
    17701 ccactccaca ttttacggat tactaaacga aagtcacaat tgccttcctt ctcatattca
    17761 agccacaact caatagggag tgttttttgc accataatat tataagccca ataggcaagc
    17821 tgggcaaaat cttgcccaaa ctcaccttcc aaactgacat aatccaatcc ttgataagaa
    17881 atagctcctg taaaatttgg attgacttgt atcgtcggag gaaagagttt atcaccatac
    17941 ccaccgccaa aaagagattt acttaaatca ttgattagtt gttggggact taaaaaatca
    18001 attgcttgtg cacatcgttt ttttagaaaa tccacaacct ctctatcatt tatttgtaga
    18061 ttctggttat aaaataaagt ataaggttca aaatatttta cataggaaaa taagtctctg
    18121 gaatactgac catcttctat taaaactgca tgaaaacggt taatatcctc tttttcaatt
    18181 atttcacgaa gggcttttga tgagtttggg taaaaataat accaactcat attttcaggt
    18241 atgtcatagt gattttccca attggcaagt cctatctgta aaatattaag ttcctttgac
    18301 atttttaacc tcctctatcc atttctctaa ttttccaaga aattgttgtc ctgtgtgctc
    18361 cttaatctta tcaattgaat atatcaagga ctcattccac tccttcaacc tatctgtgta
    18421 ataatgtgca gccttagaaa attctgtaac atctgctaac aaataaccat tttttaaatg
    18481 ttcaacatag acggtttcaa ctaggttgat ttgaggaatt cctgcactaa tcccagcaat
    18541 ctgtgtgtag agatgaggat gtctatttaa atccacaatc aaacggacaa attctagtgt
    18601 ttttatcaaa tctaactcat cattcaagtt aacaaactgt aagcgtaagt cctggtgttg
    18661 attttcttcc agaggatttt ctgcatcacc ataatcaatc gcctttccca gattttcgga
    18721 ttgaatgttt tcttggatga aagactcaac aatcccttca acctcattca tttgctcctg
    18781 actagcagca aaggctccaa aaatcacctc agtatcctta ttttcagcga caaaggacaa
    18841 gacttgaagc agagcttgat tatcaatccc ctgctcaaaa tccagttgaa aataaatgat
    18901 ggattctttc ttagtttggc ttcgtcccaa tcgtaatcgg gtgtcaaaag atgataaatg
    18961 ataacattga tgcattcgtt caggatacaa ctcctgcaac aatcgtaaac tatcctctct
    19021 atccaccaaa atcaaatccg atttttcaaa agttacatct aaatccctaa aggtatcttg
    19081 aggattacgt ccaatgaaca gactcaacag tttaggatta gtactaggta aacgatctag
    19141 taccaactgg tcatgatgag aatgagaagg aagcataaaa atatcctgat ccttcacata
    19201 cgtttgcaga taattctcaa aaaattctgc caccagatct cccatatttt gataggtaag
    19261 cattttaaag cgataaccca aaattggatt gacttctacc tgtcctcctt cttttaaacg
    19321 ctctctaaat tgccaaactc ccttaggatt caaatattct tgataggctg cttgcccatc
    19381 ttcaaaaaaa ataatactcg atataaaccc tcgatcatcc atgatatggt gcatatgtat
    19441 ttgaccattc ggtccaaaat actgtatatc actgatgaaa ccttcaactc catgttcaac
    19501 cttagcaaat ttcttcccat ttttttgaac gataatcgta aagggactat aaataaattc
    19561 acagtcatca tcccactcaa tatctctaat gcttaaaact tgggtatgga gattatgaaa
    19621 atcttgcata acatcaaaaa cggaataagt atccgtttct aacacaccat gtctatataa
    19681 aaaataacgt agatgaggct ggtaagctaa tactaataga cgagaatcta tatcttgctc
    19741 ttgaaagagc cgaatctggt gaaaggtatc atcaaactct agacgaaaat gagaaaaata
    19801 ccatggagtg atatctgcat gccatgttct ttctgaccca taccaagctg gaataaaata
    19861 atacataaaa gtctcctaaa tcaaaggtct ataggtctca tttagcctta aagccttgac
    19921 ctcgtctcta atcgtaaaaa tcatgccccc gaacatcata aataagcctg gaatcattgc
    19981 caatcgtaat aacttttcat caaacaaaac aaaaagcatg ggaccacctg ccataatcac
    20041 attaaagaga ccacctatga ctgagaaacg aaggaccaat cgattaataa atcgactagt
    20101 atccgcacct ggataaatac cataaatgta ttctccagat tttttcatac ggtctgcaat
    20161 ctcttctcca ttcatcgtaa caaaagcaaa aatgatacta aataaaaata agaccgaaat
    20221 ataaacatag acccacaaag gcttcccaac cataaattcc tttgataaag ccgctagccc
    20281 tgaatgatta gggaaaataa atcccaacaa gatgaacaaa taagctggta cactaagaaa
    20341 actcatcaca tacatataag gcatcccacc tgcaggattc aacatgattt cgagataaga
    20401 atagcgttta aatcgattgt gtaagccaat tttattaaca ggaaccaaat agcgagctcg
    20461 atacataagg gcaagcaagt aagaaaatat aatggtcata aaaacaagca agacaacaat
    20521 ccctgtaggg atataaacca gtttaaaagt ttcaataaca tcctgaggga tatttaaaac
    20581 aatgctggat aggaggatta caatagaacc cccaattccc atgctagcat ttaaatctga
    20641 caaccaaaca agaaaaaacg ttcctgctat gagtaacaag gtattcatta gagcaaccaa
    20701 aattaccgag taggaggatt gtactggcaa gctcaagcta actgccaagg attgaatcac
    20761 agcaattagc aaggtcagat acattcttcg acgatcttga atttctatag acgtagatgt
    20821 taaacccaac cgtttagaaa aagaaaacat ctgccataaa atcatggcgg acatccaagg
    20881 ggataatcca acagaaaaaa ttgataaact tcttagattc ccacctgtta gggcggctga
    20941 gaaggctaga taggctgttg aacctcctaa aaaatcttta gtatttaggt caacaaaagg
    21001 gagagtaata cgacttccca atacatagat aaacagtaga aataaggtaa atagtccttt
    21061 ttttactgct attgacgaat aaatcttagt cataaaacac tcccctcacc ttcattgttt
    21121 gtgatatggt aaataacaat tcttttattt caacttttac catttctttg ttctgcatca
    21181 aaaaacaact ttaatctgaa acaaatatct ttatattcct cagtatctgt taattgatgg
    21241 tattctaaag tttgcttata atcttttaaa agattgacaa atcgaatacg cagaacggag
    21301 acatccaaac cagccaagac acaatccgat attttcttag aaaacacttc aacaatatct
    21361 cttgcccagg aaagatcaaa ttccgttctc atgatgcttc ctgaacgtct tctatacaga
    21421 tagagattat cgtttataaa gacgatttta gaggctaaaa gataaaagcg atgcatagtt
    21481 gcttcatcat caaagcggcg accatttgaa aagtgaactt cattgaataa ttctttttta
    21541 atcaacttaa atgtcggcaa tataaaggcc gagctattga atttccaatc tcctgcttga
    21601 cggttcataa tttcttgtat agctaattct tcgacgcaaa aatctttccc tgttacataa
    21661 aaataaaaat tcccgtcact ttcgtcataa ttatagtaat tccctataac aacatctgca
    21721 tccttttctt ggacttgctg ataaagagtt tcaatcatat tttcttttac gatatcatct
    21781 gaatcaacaa tcgtgatgta ctctccctta gctacactaa tccccatatt tttagcttgt
    21841 gctgcccccc cccccttatt ttcttgatgc aatactcgca cacgattatc ttgcatcata
    21901 aaagcatcac aaatttcccc agaattatcc gtagaaccgt catcaactaa aataatttct
    21961 atattttgat aggtttgctt cagaatatgc tcgacacact ccactaaata ttttcccgta
    22021 ttgtatatcg gtaccacaac actaattaat tcactcatta ctctatctct atattcttca
    22081 ttctatccac taaatcatct ggtctctcca cagaaaaaat accgtcatag agtccatcat
    22141 ccatactttt acgtgtgata tcaaaagcga agattttctt gccactttct tgtgcccttg
    22201 taactacatt aaaaacctct ccacctgtat taatatctaa ataaactata gaatcgtcca
    22261 atagccaatc aattctacta tgtaatacat tttgatatac tgttacattc gtatactgtg
    22321 atagagaggt cagctcctca gaacaatcac acggtgcagc caaatgaaaa tgccaatcag
    22381 gtaaccgttg tactaaatac tctaaatgtt ttatatctgc actccatgtc acaagcatca
    22441 cttgtttttt agactgattg cttctttcaa aataatttaa atcggaacgt tgaaaagcaa
    22501 tctctgacca atccaaatct ctataaaccc accataattc acgtagtcta gatatactat
    22561 atgtattcca aggtttatca tgactagcat agtgaacaat tgtaggtgga ttgtcatcta
    22621 gacgttcaca ttcttgagca aggtgataaa tatcaacacc taccatataa ttatatgttt
    22681 tatctaaggc tagccaatta tcctcaaaat aaatatttaa aatactctga tccccaagat
    22741 gaacaacttg attttgctcg gccgctaatt ccaataaact attgacaata gagtgttctt
    22801 tccattttgc aacatccatt aataaaactc cagaattaaa tccagatttt cgtccttcat
    22861 aggcatagac atcatcaaca gcaccaattg aatatccttt gagatctatc tcaaacaaag
    22921 tagctagttc cccagttaca atgatatcgg aatccagata caatacccta tcagattcaa
    22981 ccacttctgt cgcaaaaaat ctaaagtaag aagcataatt tatatgaggt cctgttttat
    23041 agctttcaaa aagttcttta tcaatgtgta cactgcgaat tgtagaattc acaacttcca
    23101 tttttctccc caataattta aaccattcag gagctatatc actgttgaga atataaaaat
    23161 caacatctct attgtgatac aatacagact ttatagtcgt ctctaaagga ataagataga
    23221 cattatctgc cgctaatact attgattttc tcatactgtt ctctacctca tgtaagatct
    23281 gattgctgca accatttttt tcggaatgga gcttggatag ataccttcat atgaaatctc
    23341 agaaagattt tcagagcaag tattgtcgaa agctatcatt ggttttttgt acttaagcac
    23401 aaactcatat gcatcttcta attttcgatc atgattcaaa tccaaataca aatctgaagc
    23461 tattactatt tgttccaata acattggtaa ggaatttgga tatacggtaa cattaggaaa
    23521 acgcgttaaa gctagtagtt catttgccat atttgtataa gcaacaatat gaaaatgaac
    23581 ttctggcaat tgctccgcca aataatcgat tttctcgaca caccaagaat tcgttaaatt
    23641 aacacattgc aacttaaata tttgtgattt actaggatac ttcacactct ttgaaaacca
    23701 ttcatttaaa ataacagacc aatccatcaa agagtattcc caccaaactt ctcttagacg
    23761 tccaacagaa aattgattcc aaggcttatc ctgagaaata tagtgtaaaa ttagtggcag
    23821 tggttcgagc ggaatatcaa aaatgaattg atgtttaaag gctgccgccc cataatcata
    23881 tcctatttga aaattatatt gatcttcaag ggaactatat tgatctttaa acaacatatt
    23941 caaaattgac tggtctcctt cttccacatt ctcatgttct ttttctgtta agtcaatcaa
    24001 tttttgtcga atagtttcag atccccattt tttgttgtta atcaagagaa caccagcatt
    24061 gaagccgact cctgctccaa agcaagaacg agctgctgcc aaataatttt cacctaagtc
    24121 taattcaaac aaatcggtca aatcaccagt cacaatcaaa tcactatcta gatagagaac
    24181 tttatcttct gttacaaaat ctggaataaa atagcgtgca aatgtcatat gattgatatg
    24241 aggtaattta ttagaccaat tcatttgaaa ctgtgagcca attaacttgc agtcaatcaa
    24301 gtcgcccccc atctcttgta aatatattct tatttgacta aaccattcct gaggaatgtc
    24361 ctgatttagc agataaattt tcaaatgact attgtgtcta cagagtgact tcatcgccgt
    24421 ttcgatttgt cgaatataag cgtaatcacc tgcaaatact acagatttct tatcttgtaa
    24481 cattttatcg tctctctatc ttaattttca gttatattta ttaccattca ataaatagtc
    24541 taacatttct aaatgtcttg tttccacatt ctccttaagt tctcgttgaa ttgcaatatc
    24601 atgacgatat ttcaaataga acttcatctg gtctaaatat ttactgacat catatccttt
    24661 tagcgctagc acggcaattc gttctaacct aaaatcacaa tcatcacgca tcatcttcgg
    24721 tgaataagaa ttagaaagtc cttctttccc aaccctatac caatacaaaa ctttattaat
    24781 ataggttact ttctcaacct gcataaataa tttataattg gttcctatat cctcacacac
    24841 ccgaccaaac ggaaactgaa cttcttgaaa taattccctt ttaaatagaa ttccccaaga
    24901 agttaaaaag ctcatatcat acctctctaa taaaggaagt tcttccatta gaagttttga
    24961 attataattt ttcacataat aatcggagtc aaatacgtga atatagaata agccatctga
    25021 ctcattatag gttgaataag ttgaaacaac aatttcagaa tgctgctcct tcaaagtttc
    25081 tataagaatt gataaatact cttcagtaac ccaatcatct gagtctacaa aagtaatata
    25141 atctccttta gatctctcga ttccaaaatt acgtgcatcc gctaccccag cattttcttt
    25201 ttcgaaatag tgaaaacgac tatcacgatc agcatactct cgacatattg ctcctgaatt
    25261 atctgtagag ccatcattta ctaataaaac ttcaaaattt tgataaatct gtttcgataa
    25321 actgtctaag cagctagaaa taaatggttc tacgttataa actggtacta taacacttat
    25381 taaatctttc atacttctct ctttgataaa tcaactaaaa tctgactgtt ataggtttca
    25441 tcctcaatga actgaatatc ttgatcaaaa ttatactctg ctgtatgttt atgtgaaaat
    25501 ttaaccttag ttttagcacc catcttcatc cactcatact cggagtcaat atgcccaata
    25561 tctaagactt ggtaaccctt tcgacttaaa tgataggcta aaacttttgc tgtaggaccc
    25621 agcatacata aaatcagtct tccttcagca tgtttcataa tttcctcttg aatgttatcg
    25681 acaacggaat aagcattatg agatggacaa ataatccgtt tcacagattt gaccttatca
    25741 aataaatcat ttccaacccc agagcgagat gtaatcccct ctacaatcag aatatcccta
    25801 ttctcccaaa tactctttag cttttcaaat tgtccttttg ccttactctt atcttcataa
    25861 tcaatgtatg gacgcgagat aaaggtagag ccataccatg aacccttaca caactcttta
    25921 taaaaatcca tataaacatt catatgttct ttccagaatg gtgtagccca ccaagtaaag
    25981 acaaaacgat cgtcaaaagc atcaggtaaa caaaccacta atttctcgtc actctcaaga
    26041 cccacaatat gttttaattg gttagctaac tctagatcat gattttgata aggtataggc
    26101 aaaccccaca tcaaattgac ttctccgtct ccaaaacgaa ctaaagaaga gttgtgttca
    26161 ataatataat ccaaggtttc atctatccct ttcacctgga ttatatcaag cggtttttct
    26221 agcatatcct tagttatcaa tttttgcaaa tcagccaaca ttcgttcagg atgttcactt
    26281 gaatacaacc tttggccatt attcccattt tgagatttat aaaaggctag tataggttta
    26341 gatagatgag ccatttctgc aacgatatcg gatgttgaag tcagtaggtt gatatctaaa
    26401 taagcatcca tcttctcctt caactcgtct agcttatctc tagaaattgc cggatagagc
    26461 tgaatattag gataacgatt agacaaatca tataattttg gccccatagc tgtccaagca
    26521 gcaacttgaa aaacaacatt tggcaactgt ccagccaagt aatccaattg ttcgatatcc
    26581 tgagaagccg taaacgttaa acaagttaaa cttggaagtt gtcgaaaaca ggtaagatgt
    26641 ccgtttttct taaaatcttt aatcgtatca atcataaagg aaactttccc attttcgaaa
    26701 acgatttgtc ctaactctcc gtgctgagtc gattgaaaag ctagtagcgt tttttcttgt
    26761 tcttgcaaag attttaaaaa gttctcatct gcactaccat gattgatatc caaatataga
    26821 tttgttgact ttttcagctt atctaataca ggaggaacaa tttgtggatg caatctcaca
    26881 ttattatata cagctaattt ttttaattta tctcccatat ccgtccaagc tgcgatatga
    26941 aataccacct caggtagagc tgtaactagc tcttctattc cttctaaatc ttgggaattc
    27001 gttaaggtta agcaagaaaa ttccttatct agaggcgata ttagttcaaa ttctcccaaa
    27061 tgatgttgta aaatctgatt ccactccaaa tcatggaatt cccaccataa atcacgataa
    27121 cgattggctg tcaaggtggt ccagggtttt ctgtaggtcg taaaatgaat caccactggt
    27181 ttatcattaa aagccagatg ttcctgccaa ttgttataca aagccacaat atcatgccct
    27241 acttgtaaat tataagctcg acctagttct aaccaatcat cttgtaagac ctgattaaaa
    27301 atcgtttgat caccattaaa atgctcgaaa cggccttctt caacttcctt cattgtaaca
    27361 atgctctgtt caattagtcg ttcttttaat ttctcttgac gccatttttc attgttgatt
    27421 agtagaacac cagtattaaa accttgacca tttgcatctc taatcgctgc gatataatgt
    27481 tctcttacat cctgctcaaa tagactatct aatttatcat tgataagcaa gtcacaatct
    27541 aaatacaaaa ccgtatcttc ttgtatataa tctgggataa aatacctagc ataggcaatt
    27601 gaactaatgt gagcctgttt tttccaatct tgaaacacag tttgttcagg tagtttaaca
    27661 tcgataatct cactacctaa catgctagct atttttcgtg gctttcgaaa ccaatctggc
    27721 atgatatctt gatttaaaat ataaatctta acatctcgat tgtggtataa aatagatttt
    27781 atggttgttt ctaactgcct ggtgtaatta cgattaccag ctaatacaat tgttttaatc
    27841 atcttgttct cttattcaac tcccaaatgg taaattgcat ctaccaataa ttttttagta
    27901 aaataacctt cttttagcaa ataactaaag gtttttatcc gattcgtcat ttcttgatat
    27961 tcttgtagat tcattttatc aactatctca tgaacttcct ctagactatt cgccacaaag
    28021 cccaagcctt gatctactat aaatttagca gttgataagt tgctcggtac aatcactggg
    28081 ataccagctg ttagataggt actaacctta tgagatatat tcaaggtata gtattggtta
    28141 ctttctccct cattttgatg ggttccccag acaaggccaa atccaccctt tgataattct
    28201 agcaacaatt cctcatcttt tttccatcct tcgatgctga gatttctagc actagaaccg
    28261 gcctcccctt tatttgaaaa tactctcaaa ggcgtatctt gagaccaatt ttgtaagtct
    28321 ggaaaacgct ctaaacttcc agcaaaaaaa gttctttttt taaaagcagg ggtgtataag
    28381 gataaatcat gaggatgatc ccacatccct tgaacaagaa tcttcttagt cgtcaatcct
    28441 tcttccatca ggcgtgtttt cattctctct gacggcacta tcaaaacatc tgatagatta
    28501 tacatgtaca tatagtcttt catgagataa tagttactat caaacatgag gggaacaaca
    28561 tcatggataa agcaaataat tttcacctgc atatccttta gcttatcaaa caagagacga
    28621 tcaaattcaa agccattcca ggttggagac tgaaagacta agatatcacc aatagagata
    28681 ctggccataa taccatccag acgcttattc atttcagaag gactatctga agcaatgttg
    28741 taaaaataaa taccaacctc tctaaatccc agttgactag ctatcttttg aacagcattt
    28801 tgagctaaga taaccgtact atcaccagcc atgccgtata aatttgttaa atgtaatttc
    28861 atattacgct atctcatttt ttattactat ctacggaagt aaagacaatt tttccatcat
    28921 tcttctataa atctctgtga actgcatatt ttgttcttct aattttgcta ctactctttg
    28981 taatctattt ttataaatca aaatatgatt ggtcaagtca tagtctgaac ttgctaaaat
    29041 agctatcttt tcttccctag ccccaatttc atcatacata cgcttttcac tccatgtatt
    29101 cgataaagta tcagataaac caacacggta ccagtaaaca caacgattca aatagactat
    29161 cctcgaagct cttagaagta ccttccatgt ccagtaagta tcctctgcaa tttttcctat
    29221 aggaaatggt aaatcttgta gtaactctct cttgaataac ttcaagacag ctacagtcca
    29281 gttcccattt ctgacttctt cgacaccttc cctatccata attgctttac cttctatcac
    29341 ttctagagaa tcatctggat ccgtaacata agtcatatac acatagcgtg tttcatcata
    29401 agaattataa cgcccgatac taatatctgc gttttccttt ttcaaagcac catataatcg
    29461 gtctaaagca tcatgttcca accaatcatc agagtctaca aaagtaatgt acgccccccc
    29521 ccgaacattc aatacctagg ttacgagctg atgaaagacc gccgtttgct ttctcaaaat
    29581 atttgaaacg agaatctttc tctacaaatt cttcacatat tttggatgaa tgatctggag
    29641 agccatcatt gattaataaa cactcaaaat tttgatacgt ctgattctga atgctatcca
    29701 aacacattct cagataattt tccacattat atattggaac aacaatactg attaactcat
    29761 tctccattga cttattctcc taaaaatttg cgaatagcat ctaccatctt atctggctca
    29821 gttgctgaaa aaatccgact tcttcctttg ctatcatgac tagtattatc aaaactaaag
    29881 attggcttat tgcgcctaca gacttcttct ataatgttga caatctctcc ttcatggtta
    29941 atatcaagat agaaatccat cttatccaag gtttctttca tattaaaaga attaaaattt
    30001 ggaaaaagtg aaagattcag atatctctgt aaatcaacaa cagagggagc aaaatttgta
    30061 tgcgccaaga tcgtaaagtg cacttctggc aattccgata ggagatattc caaggactcc
    30121 attgcggcac tatttgtaaa aatacaagta tgatataagg gaacacccac taactcctta
    30181 aaagagcgtt taacgatatc tgaacttaac aacacatcgt tccagttcaa tccataataa
    30241 aaccaccaga gtttacgaaa acgtgtaagt gttaaatgag tccacggttt gaactctgta
    30301 gtataatgga caatcttagg ctcgtaattt ccataatagt tggattggta ccagtcagca
    30361 ttacctttta aatgtaaaaa ctgatctaaa ccaaccatga aattatactc tttgtccaaa
    30421 tgtagccact ggtcaccgaa atatatattg agaacacctt ggtccccata gacatgttca
    30481 tggtgttgag cagtcaactc tagcaaattt tgtgttgatt ttttttctcg ccattttttt
    30541 gcatcaatca ataacatacc tgaattaaat gttgttaacc aaccatcttg atcaaaatct
    30601 tgaacagctg cgatagcgta tccttgcaaa tccaaaaaaa ataattcatc caaattggca
    30661 ttcacaatga tatccgagtc taagtagagt acccgatctt caagcacttc gtctgctatg
    30721 aaatacctaa agaaagttgc ataggacagg attgcatttg gcaagtggaa atcacgaaga
    30781 ttgtgatctg cttttttgac attaataatc tcagaaccaa taaccttcag acgatttctc
    30841 atcaaaagaa accattcact aggcagatca tcattaaaca cataaaattt cacttcgtga
    30901 ttatgaactg aaactgactt tataacggtt tctaccttat caagataatg aatatcagct
    30961 cctaaagcaa taacttttct atacattctt atctcccgat ttttctattt tataaacaaa
    31021 tcatctattt taccaactga aaaaacgtga tttctacttt tgagatattg attttttact
    31081 tctgtttcat caacaattac agtatccttt tcttcgatga tatcttttca tttctaaatc
    31141 taaatgttga atcaaaaaat cttcaaatca attatgctat gaataagatt tctttcgtgt
    31201 tctgcaaaat ttacaactat ctacttatag attcggcatt atcaaataga ttaaagactc
    31261 accattaaga tatcctctga agtcatgttt ggttttcttc caaccttaga aagtttcatc
    31321 taacttgatt ttatattact cattaaactc tcatctttac aaaaagattt ccattattat
    31381 aaactacact gtttgatgga atatcattgc gtatgagaca acctgctcca ataatggtat
    31441 tatctccaat cgtcactcct tttaaaatcg tgacattact tcctatccag cagtctctgc
    31501 caactctaat cggcgctgta gtccactgcc acttttcaat cttttcagcg gtataaatat
    31561 ggtcgtgatc ataaaaacga acaccctctc ccatcatggt accagctccg atttcaattc
    31621 tttccataca gttaaaacta caagagttgt tgataaaaac accattattc aggattaact
    31681 taccagaaga gacatgaaaa ttttcaaaat ttctacaggc gacattggct cctacaatga
    31741 agtgagcctt atcatcgatt ttaaagacat tccaagtccc atcttgaatg attttctctt
    31801 gatgattggt gcctactctg acttcattca gatagtctct cactctagaa accaatttgt
    31861 ctggtgtact tgatagaaaa acttcctgcc cctgatttcc atggactgta ttgtcaaatg
    31921 caaagacaga ttttccagcc tgtacaaact tggagacaat agcatctact tcttgaaagt
    31981 gattgatatc tagtaaaaag tcacaggtat cgactaaaaa gtttagctgt tcttcatttg
    32041 taatcgttcg gagacggaca ttatagttcg tttctaagct acggattttc tcggaaaatt
    32101 gaacaggtgc tgcaatatga aaacagatat ttgacaagga ttcaaggaga taatccaact
    32161 cttcaatctg atcactaacc gtcaaaatca gagcatctcc tactaaatga tttttcttca
    32221 tttgcttatt tctctcaatt tctcaatcat tgcttgaact tggtcaacag catatgcctc
    32281 ctgacctact tcataggttt tagtattttc aaaggataag ataggcttgc caagattagc
    32341 aaattgatcg agaatttctt ctgtcttttc gccatgatta atatctaaaa gtacttgact
    32401 ggtttctacc aattcattat cgacatctac caaatagtga attccgttaa atatagtcac
    32461 gtttggataa attgtcatct gagccaatcg atcactaact attactctag ctgctatctt
    32521 aaactgaata tcaggcaagg attgaaccaa tgtctcaatt tgttcaatat ggtctgaggc
    32581 agtatagatt agacaagtga aaggttcctt tattggatag atgtgagatc tttgtaatgg
    32641 atgtaaatga tggttttgtc ccaattctgt ccattcaagc ccatgatagt accaccaaac
    32701 ttcacgataa gtttgggccg ccaaatcttt ccacggtttt ctatgggaaa ggtagtgaat
    32761 aatagcagga taatcctgac cctcaggcaa ttgataatca gcaaactgtt tatgaatgac
    32821 aatatgatta taatcaaaat ccaattccag ccatttatgt tcaaaaagca tattcaagat
    32881 gctctgatct gcctgatcca ccttatcatg ccattcattg gttaaatcaa ttaatttttg
    32941 ggtcatattc tcttttttcc aaaaagcatt gtttaccaag agaacaccgg cattaaagat
    33001 ttcttgacca aaataagctc tgcccccaaa atctctaaca gcagccaaag gataatcttg
    33061 taagtctgta gcaaacaagt catccagatt tttcgttaca actagatcac agtccaagta
    33121 gagggccttg tcttcttgca cgaaatcagc tatgaaatag cgtaaaaaga ctgtgtaact
    33181 aatatccgat ttataacatg aaatttgctc agaagttacc cgacaattaa taatttctga
    33241 gtcaaacttc tctaatcgct tatttaattg tttgatccat tcatttggaa aatcgctatg
    33301 aatcaaataa aaacgaagcg agcgattgtg gtaacagata gacctgattg tcgttaaaac
    33361 ttggtctaca taggcataat tcgccgctag gacaatggct ttcttttcac ttgattcttg
    33421 taccgttaac tgatttaaaa gtcttttttt catttcaaac tctttatacg ttgctgtgtc
    33481 agataaacca ctagcttgac cgttggcgag actgaattcc aacatttgac gataaatcgc
    33541 caaatgcttt tctaaagggt aacccatatt agctagtagc gtaatgcgtt cggacatggc
    33601 atcaaccaat gcatgcatcc acttttctgt ccaaactctt gataaactac cttttctaat
    33661 ccgattattc ttcatcatca cgtttacggc gtttcgcaaa caaacccaag ccagtcacag
    33721 ctgccaaagc tccaaggagt acagatgact tggaagcttc tgtacctgta tttggcaatt
    33781 gctgtcttga cttacctgct gaagttgacg cgcttgcgct tgttgatgcc gattcagacg
    33841 ctgaagccga cgcactcgtt gatgctgaag ctgaagcgct tgtcgatgct gaggctgaag
    33901 cactggttga ggccgattca gaggcacttg tacttgctga agctgacgca ctggttgacg
    33961 ctgaggctga ggcagacgtt gatgcggatt cagacgcact tgtacttgct gaagccgaag
    34021 cgcttgtcga tgctgaggct gaagcactgg ttgaggccga ttcagaggca cttgtacttg
    34081 ctgaagccga cgcactcgtt gacgctgaag ctgaggcgct tgtgcttgct gaagctgaag
    34141 cactcgttga cgctgaagct gacgcactcg ttgatgctga agctgaggca cttgtcgatg
    34201 ctgaggctga ggcactcgtt gacgctgaag ctgaggcgct ggtacttgct gaagctgatg
    34261 cactggttga cgctgaagct gaagcactcg ttgatgctga gactgatgca ctggttgacg
    34321 ctgaagctga tgcactggtt gaggccgatt cagaggcact cgttgacgct gaagctgagg
    34381 cgctggtact tgctgaagct gacgcacttg ttgatgctga agccgacgca ctcgttgacg
    34441 ctgaagctga ggcgcttgtg cttgctgaag ctgaagcact cgttgatgct gaggctgatg
    34501 cacttgtgct tgctgatgta cttgcgctgg ttgacgctga agctgaggca ctcgttgacg
    34561 ctgaagctga ggcactcgtt gatgctgagg ctgaggcgct agtacttgct gaggatgagg
    34621 cactggttga tgccgattca gatgcactgg ttgaggccga ttcagacgct gaggtacttg
    34681 ctgaagctga cgcactggta cttgctgagg atgaggcact cgttgatgcg gaagctgacg
    34741 cactggtact tgctgaggct gacgcactgg ttgatgctga ctcagacgca ctcgttgacg
    34801 ctgaagctga cgcactcgtt gacgctgaag ccgaagcact cgttgatgct gaggctgacg
    34861 cactggttga tgcagattca gaagctgatg tgcttgctga ggctgacgca ctcgttgatg
    34921 ctgactcaga cgcactcgtt gacgctgaag ccgaagcact tgttgatgcg gaagctgacg
    34981 cactggtact tgctgaagcc gaggcactta ttgatgctga ggctgaggca ctggttgacg
    35041 ctgaagctga ggcgcttgtc gatgctgagg ctgaagcact tgttgatgct gaagctgagg
    35101 cactagtact tgctgaggct gacgcactcg ttgatgccga ttcagacgct gagatacttg
    35161 ctgaggctga tgcactcgtt gatgctgaag ctgaggcact agtacttgct gaggctgatg
    35221 cactggttga ggctgaggct gaggcgctag tacttgctga agccgacgca ctggtgcttg
    35281 ctgaggctga cgcactggtt gatgcggatt cagatgctga tgtgcttgct gaggatgagg
    35341 cacttgttga tgcggaggct gaggcgctgg tgcttgctga agccgaggca cttgttgatg
    35401 cggattcaga ggcactggtt gacgctgaga ctgaagcact cgttgatgct gaagccgagg
    35461 cacttgttga tgcggattca gatgctgatg tgcttgctga gactgatgcg cttgtgcttg
    35521 ctgaggctga agctgaggca cttgttgatg ctgaggctga cgcactcgtt gatgcagatt
    35581 cagacgcact ggttgatgct gaagttgagg cactagtact tgctgaggct gaggcactgg
    35641 tacttgctga agccgacgca ctcgttgagg ctgaagctga ggcactcgtt gaggctgaag
    35701 ctgaggcact ggttgatgct gattcagacg ctgaggtact tgttgacgct gaggctgagg
    35761 cagacgttga tgctgactca gacgcacttg tacttgctga agctgaggca ctcgttgagg
    35821 ctgaagctga ggcgcttgta cttgctgaag ccgacgcact ggttgacgct gaagccgacg
    35881 cacttgtcga tgctgaggcc gaagcactgg ttgacgctga agccgacgca cttgttgagg
    35941 ccgattcaga cgctgaggtg cttgctgaag ctgaggcact tgttgaggcc gattcagacg
    36001 ctgaggtact tgctgaagct gaggcgcttg ttgatgctga agctgaagca ctcgttgatg
    36061 ctaaggctga ggcactcgtt gatgctgaag ctgaggcgct tgtcgatgct gaagccgatg
    36121 cactcgttga tgctgaagct gaggcgcttg tcgatgctga agccgacgca ctagtacttg
    36181 ctgaagccga cgcgctggtt gatgccgatt cagaagctga ggtgcttgct gaagctgatg
    36241 cactggtact tgcagaggct gaggcgcttg ttgatgcgga agctgacgcg ctggtgcttg
    36301 ctgaagctga ggcactggtg cttgctgaag ctgaggcact agtacttgct gaagctgagg
    36361 cactggttga tgctgaggtt gatgcgctcg ttgaggctga agctgacgcg cttgtacttg
    36421 ctgaggctga tgcactcgtt gatgctgaag ctgaagcgct tgtcgatgct gactcagacg
    36481 cactcgttga cgctgaagct gaggcgcttg tgcttgctga agccgacgca cttgtcgacg
    36541 ctgagactga cgcacttgta cttgcggaag ccgaagcact tgttgatgct gactcagacg
    36601 cacttgtact tgcggaagcc gaagcgcttg tcgatgctga ctcagacgca cttgtacttg
    36661 cggaagccga agcgcttgtc gatgctgagg ctgatgcact ggtgcttgct gaagctgaag
    36721 cgcttgtcga tgctgaggct gaagcacttg ttgatgcgga agccgacgca ctggtgcttg
    36781 ctgaagccga cgcactggtg cttgctgagg ctgacgcact cgttgatgct gactcagacg
    36841 cactcgttga cgctgaagcc gaagcacttg ttgacgctga ggctgaggcg ctagtacttg
    36901 ctgaagcgga cgcactcgtt gatgctgaag ctgaggcact agtacttgct gaggctgatg
    36961 cactggttga ggctgaggct gaggcgctag tacttgctga agccgacgca ctcgttgatg
    37021 cggaagctga cgcactggta cttgctgagg ctgaagcact tgtcgacgct gaagctgaag
    37081 cgcttgtcga tgctgaggct gatgcactgg ttgacgctga agctgaggcg ctggtacttg
    37141 ctgaggctga agcactcgtt gatgcggatt cagaggcact ggttgacgct gagactgaag
    37201 tactcgttga ggctgaagct gaggcactcg ttgaggctga agccgaagca ctcgttgatg
    37261 cggaagccga cgcactcgtt gatgcggaag ctgacgcact tgttgatgct gaagctgaag
    37321 cacttgttga tgctgaagct gaggcacttg tcgatgctga ggctgaggcg cttgtacttg
    37381 ctgaggctga cgcacttgtt gatgcagatt cagaagctga tgtgcttgct gaagctgagg
    37441 cacttattga tgctgaggct gacgcactgg ttgacgctga agctgaggca ctggttgatg
    37501 ctgactcaga tgcactggta cttgctgaag ctgaagcact cgttgatgct gaagccgagg
    37561 cgcttgttga ggccgattca gacgctgaga tacttgctga agctgacgca cttgtcgacg
    37621 ctgaagctga agcgcttgtc gatgctgagg ctgaagcact ggttgatgcc gattcagagg
    37681 cacttgttga cgctgaggcc gaggcgcttg tcgatgctga ggccgaagca cttgttgatg
    37741 cggaagctga cgcactggta cttgctgact ctgatgcact ggttgacgct gaagccgaag
    37801 cactcgttga tgctgaagct gatgcactag tacttgctga ggctgacgca ctcgttgatg
    37861 cagattcaga cgcactggtt gatgcagatt cagacgctga ggtacttgct gaggctgacg
    37921 cactcgttga ggctgaagct gaagcactgg tgcttgctga gactgatgcg ctggtacttg
    37981 ctgaagctga ggcactggtt gatgcggaag ctgaggcact tgtcgatgct gaagccgaag
    38041 cactcgttga cgctgaagcc gacgcactgg tgcttgctga agctgatgca ctcgttgatg
    38101 cagattcaga cgctgatgtg cttgctgagg ctgaagcact ggttgacgct gaagccgacg
    38161 cactggttga agccgacgca ctggtgcttg ctgaagctga ggcgcttgtg cttgctgagg
    38221 ctgacgcact cgttgatgct gaggctgagg cgctttgact agcacttact gagagtgact
    38281 tagactgtga aagtgactga ctggtcgtgc tagattcaac tacctttcct ctaccattga
    38341 agtagttagt tctaatgtta tctgttttag cagcgtaagg ggtaaatgta aaggatgtat
    38401 ccgttccagt aattggtaca gtccaagatg atgttaatcc atattctctc ttagcctgcc
    38461 aaccattcat ttgggcacca tttccccaag tatacctact accccgcttc gtcattgtag
    38521 atgtattata gtattgaacc tgtccaccat ttttgttagt aatggagttc tttacatctg
    38581 aaggggtacc aagaccactg ccaagggtta acattgtttg tattgaagtt cctgtattat
    38641 agatagaata tccattactc atcttttttg atatattacc aagagtcttt gttttaggat
    38701 ccacatacgt aaccgtatag gtaaaggtca gttttaagcc atcatttgtc actgtcaatc
    38761 gatagtaaat tggaacatta tataccgaat ctacaccttt acctgtataa acttttgtct
    38821 cacttttagc aatgtttaga cttgcattaa ttgcaggggc gccatttaca atcgtattgc
    38881 cagaaaaaac agcagctttt atagaagcca gcaattgctc gatggaatcc actgaacgct
    38941 tgcgtcgctt agcataagat tggagattga catttgtaac tgatgctaca taatcactag
    39001 ctggtttctt acgatcttct tcgaccttct tagcagttgc ttctgtagcg gcagctgttt
    39061 gtgatcctac cacagtagat gatgcagaga tacttgtcga agccgatgta cttgctgatt
    39121 ctgatgcact tgtactcgct gaggtcgaag cgctggttga ggctgactca gatgcagatg
    39181 tacttgccga ctctgaagct gacaaactag ttgaactcgc tgaattactt gtagatatcg
    39241 tacctagaac tactgtacca tttgttgcca aagcatccgt tttctctaca gttttttcaa
    39301 gtactgccga ctcatttgta aataccttcg tttgagttgc aacggttcca cttatgacag
    39361 ttcccgcagc aactatcccc ttgaggatat caagcccagt aattgaatga cttactttat
    39421 cttctaccgt ttcggtcatg acctgagtag tatcaacacc accacgcatg accttaaaca
    39481 agccaaaaag agaagtcgag gcccgtagcc aatgcttccc tgatttgatt aatttgaacc
    39541 gagttactcg gtctgtttct ctatattcac ccttctgacg tctaaaaaat attttgaaat
    39601 ttcctttcga gtattatttt catgtatgga tata
//
LOCUS       DAVLCS010000017        36338 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLCS010000017 DAVLCS010000000
VERSION     DAVLCS010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36338
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.017"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(45..893)
                     /locus_tag="VXC78_001003"
     CDS             complement(45..893)
                     /locus_tag="VXC78_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0583105.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSKLTEITIEAEI
                     LVGKAF"
     gene            1045..1323
                     /locus_tag="VXC78_001004"
     CDS             1045..1323
                     /locus_tag="VXC78_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583106.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            1325..3388
                     /locus_tag="VXC78_001005"
     CDS             1325..3388
                     /locus_tag="VXC78_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0583107.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRICVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(3466..4722)
                     /locus_tag="VXC78_001006"
     CDS             complement(3466..4722)
                     /locus_tag="VXC78_001006"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV0583108.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            4864..7329
                     /locus_tag="VXC78_001007"
     CDS             4864..7329
                     /locus_tag="VXC78_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0583109.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKAGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            7394..8305
                     /locus_tag="VXC78_001008"
     CDS             7394..8305
                     /locus_tag="VXC78_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0583110.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            8535..9233
                     /gene="dapD"
                     /locus_tag="VXC78_001009"
     CDS             8535..9233
                     /gene="dapD"
                     /locus_tag="VXC78_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV0583111.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDDQ
                     TQQKTALEDALRTL"
     gene            9301..10431
                     /locus_tag="VXC78_001010"
     CDS             9301..10431
                     /locus_tag="VXC78_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV0583112.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            10443..10982
                     /locus_tag="VXC78_001011"
     CDS             10443..10982
                     /locus_tag="VXC78_001011"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV0583113.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            10966..11643
                     /locus_tag="VXC78_001012"
     CDS             10966..11643
                     /locus_tag="VXC78_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV0583114.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(11715..12614)
                     /gene="galU"
                     /locus_tag="VXC78_001013"
     CDS             complement(11715..12614)
                     /gene="galU"
                     /locus_tag="VXC78_001013"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV0583115.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(12636..13652)
                     /locus_tag="VXC78_001014"
     CDS             complement(12636..13652)
                     /locus_tag="VXC78_001014"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0583116.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            13864..14303
                     /locus_tag="VXC78_001015"
                     /pseudo
     CDS             13864..14303
                     /locus_tag="VXC78_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(14418..14843)
                     /locus_tag="VXC78_001016"
     CDS             complement(14418..14843)
                     /locus_tag="VXC78_001016"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0583117.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(14911..15561)
                     /gene="phoU"
                     /locus_tag="VXC78_001017"
     CDS             complement(14911..15561)
                     /gene="phoU"
                     /locus_tag="VXC78_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0583118.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKTLLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(15576..16328)
                     /gene="pstB"
                     /locus_tag="VXC78_001018"
     CDS             complement(15576..16328)
                     /gene="pstB"
                     /locus_tag="VXC78_001018"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0583119.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(16330..17145)
                     /gene="pstA"
                     /locus_tag="VXC78_001019"
     CDS             complement(16330..17145)
                     /gene="pstA"
                     /locus_tag="VXC78_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0583120.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(17138..18001)
                     /gene="pstC"
                     /locus_tag="VXC78_001020"
     CDS             complement(17138..18001)
                     /gene="pstC"
                     /locus_tag="VXC78_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0583121.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(18119..18994)
                     /locus_tag="VXC78_001021"
     CDS             complement(18119..18994)
                     /locus_tag="VXC78_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEV0583122.1"
                     /translation="MKFKKILTLAAIGLSGFGLVACGNQSATSKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(19161..20492)
                     /locus_tag="VXC78_001022"
     CDS             complement(19161..20492)
                     /locus_tag="VXC78_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV0583123.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(20493..21200)
                     /locus_tag="VXC78_001023"
     CDS             complement(20493..21200)
                     /locus_tag="VXC78_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0583124.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGKQEGDDSDNIADNSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(21284..21769)
                     /locus_tag="VXC78_001024"
     CDS             complement(21284..21769)
                     /locus_tag="VXC78_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0583125.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            21755..22313
                     /locus_tag="VXC78_001025"
                     /pseudo
     CDS             21755..22313
                     /locus_tag="VXC78_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(22628..24319)
                     /locus_tag="VXC78_001026"
     CDS             complement(22628..24319)
                     /locus_tag="VXC78_001026"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV0583126.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            24455..24901
                     /gene="argR"
                     /locus_tag="VXC78_001027"
     CDS             24455..24901
                     /gene="argR"
                     /locus_tag="VXC78_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0583127.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            24952..27486
                     /gene="mutS"
                     /locus_tag="VXC78_001028"
     CDS             24952..27486
                     /gene="mutS"
                     /locus_tag="VXC78_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV0583128.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            27633..29327
                     /gene="patA"
                     /locus_tag="VXC78_001029"
     CDS             27633..29327
                     /gene="patA"
                     /locus_tag="VXC78_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV0583129.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(29657..29920)
                     /locus_tag="VXC78_001030"
                     /pseudo
     CDS             complement(29657..29920)
                     /locus_tag="VXC78_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            30118..31884
                     /gene="patB"
                     /locus_tag="VXC78_001031"
     CDS             30118..31884
                     /gene="patB"
                     /locus_tag="VXC78_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV0583130.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            32023..32712
                     /locus_tag="VXC78_001032"
     CDS             32023..32712
                     /locus_tag="VXC78_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0583131.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            32716..32895
                     /locus_tag="VXC78_001033"
     CDS             32716..32895
                     /locus_tag="VXC78_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583132.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            32882..34231
                     /locus_tag="VXC78_001034"
     CDS             32882..34231
                     /locus_tag="VXC78_001034"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV0583133.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVIIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            34355..35815
                     /locus_tag="VXC78_001035"
     CDS             34355..35815
                     /locus_tag="VXC78_001035"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV0583134.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            35829..36263
                     /locus_tag="VXC78_001036"
     CDS             35829..36263
                     /locus_tag="VXC78_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0583135.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVSELIPYWWGEERASKFNER"
BASE COUNT        10589 a         6957 c         8008 g        10784 t
ORIGIN      
        1 aaccatacgt acggcaaggc gacgttgacg tggtttgaag agtattagaa tgctttccca
       61 accaaaatct ctgcttcgat ggtaatctct gtcagtttgc tccagtcaat tttgctctgg
      121 tcaacgtgaa agaggagagg agtcatactg agtagggctt ggagttgttc tgctgtgata
      181 gtcttagtca gagaggcagt ttgactagat aggatggtaa agtgttcctg gaaatgctcc
      241 ttgatatctt ggttagaata ctccttgttt gtcagctggt cctgtactct ttgacggatt
      301 tctttgaggt gattttcagt tgggataacc tttatcaaga taccgtcttt ggataaaacg
      361 cgacgaaatt ctccatagtt ggcaggtgag aagatatcaa gcagaatatc catgttagcg
      421 tcttttatag gaagtcgtgc caagtcgcca acgaaccaat tgactgccca gttgggttca
      481 cttttagcag cgatttggac tgaatctttg gagatgtcaa aggcatagaa agttttttca
      541 gagtgacttt cttgtagttt gcgagaatag aatccttcac cacaaccgat atccaaaatt
      601 gttgtggtag tttttgagct tgcaagcaag tcagatacag catctaagat agcttggtaa
      661 aagccggctt ctaggatttg ttgacggttt tgaaaatttt ccttgtcata gttagcagat
      721 tgcttgattt gaggtgctag attgacatag ccaaatttcg ccaagtcaaa agaatgacgg
      781 ttgcagcact tgaaattagt ctctaacaga gtcagatttt cttgacagat aggacaggca
      841 aaggcagtcg cagaagcaaa acgctgaagt ttgggcttga gatttgtatt catagtttaa
      901 gtgtatcaaa agaggcaaat gaaagcaact ttaggaataa gtagatggga gattcagtag
      961 aaataaaact aattctccaa tttatagaat gaaattgctt ttatatctaa attgctatat
     1021 aataatgata aggaggaaat aagtatgtta aaagaagtat taaccgttgc aaaagttgcg
     1081 aaaaaatctt cattattttt gggtggtgtc gcatttggta cccttggttt gaaaatctta
     1141 gcaagtaagg aagctaaaaa aggttattct aaagctttgg ctaaggctta caagttgaaa
     1201 gacgagctag atgcatctgt ttctgtcgtg aagcaacatg gagacgatgt cttgcaagat
     1261 gccaaatatt tgtacgagca agagaaaaaa gaagagcaat tagatagcct tataggtgaa
     1321 taatatgtct tttaaagtgc tacatagagg ataccaacat atccgactat catcttcttt
     1381 ttcacttacc ttggatattc aagactatct tcgttccttg gcgagagatg aaaaggggat
     1441 tgagtctatc cagttttaca tggatcaaca gcactttact ctacgcataa aagaaggctt
     1501 ttctgtatta gataatgcag aagccttttt aaaaagaatt gataaaggga aagtttctga
     1561 gttgatgact cttcccattc gtagagaaga gagtgcttat tctattgttt caggtgcagc
     1621 ggttaagcgt gtactttttc gtagttttgt gccgtatcct attcgctata tatggacttg
     1681 ttatcaggct ttgggttata ttagagaagc ctatcaaaca ctagcgcgta aggaactaac
     1741 gatggaagtc ttggactgtt cggctatttt attgtctttg tttatgaacc aatccaagac
     1801 agctagcaat atcatgttta tgcttgattt ggggaatcat ttagatcagt ggtccttgaa
     1861 aaaaactgca acagatttag aacagagtct tcttgcaaaa gagagcgatg tattcctagt
     1921 acagggcgat acagttgtta gtatcaagag ttccgatgtt caaataggag atgtcttgat
     1981 cttatctcaa ggaaatgaaa ttctgtttga tggacaagta gtttcaggtt taggtatggt
     2041 caacgaaagt tccttgacag gagagagttt tccagttgaa aaaagagagt ctgatttggt
     2101 ttgtgcaaat acagtattag aaactggaga gttacgcatt tgtgtaacag ataatcagat
     2161 gaacagccgt attttacagc tgattgagtt gatgaagaaa tctgaagaaa acaagaaaac
     2221 gaaacaacgc tatttcatca agatggcgga taaagtcgtc aaatataatt tcttgggggc
     2281 tgggctgact tacctattga caggttcttt ttctaaggct atttctttcc tattggtcga
     2341 tttctcctgc gctttgaaaa tctctactcc tgtagcttat ttgacagtta tcaaggaagg
     2401 gttgaaccgt gaaatggtga ttaaggatgg agatgttctg gagaaatatc tggaagttga
     2461 tactttcttg tttgataaga caggaacaat cacaactagt tatcctatag ttgaaaaggt
     2521 gttacctttt ggagactata gtgaggaaga tattctcaga atcagtgcct gtcttgagga
     2581 acacatttat catcctattg ctaatgccat cgtcaagcaa gctgagatag agggaattga
     2641 acatgaggaa atgcatggga aactccaata tatcgcaagc aaggggatca aatctcatat
     2701 agatggccaa ccagttctta ttgggaatta tgtcttgatg caggatgagc agattcatat
     2761 cagttcagaa caaaatgctt taattgaaga gtacaagagt cactacaatc tcttattctt
     2821 ggcttatcaa aatgaattga ttggaatgtt ctgcattcat actcctttga gaaaagaagc
     2881 aaaaacagcc ttggataaac ttaaggcaca ggggaaaaaa ttgattctgg caacaggaga
     2941 caccttgatt aggacagagg aattagtcaa agatttgccc tttgatcagg tctatacaga
     3001 cttgaaacct gatgggaaat ttgagttagt agagaaactg cagaaagcag gtcacactat
     3061 tttgatggtt ggagatggat tgaatgactc agcggcttta actctatcag atatcggtgt
     3121 ggtgatgaat gagagtgcag atatttctaa gcagatgagt gatatcttat tgttagataa
     3181 tcgtttggat ttcttccaag agttggattc gttatcatca tctttgcaaa cactcatcaa
     3241 gaaaaatatt caggataccg ttgtcgtaaa tagtagtttg attggctttg gcttatttaa
     3301 ttggttcagt ccttcaaatc tctctatctt acataatcta acaaccttgc gcattgtcct
     3361 gcgtagcctg tctattaaaa atagatagat gagagttatt aacagcaaaa aggagttacc
     3421 tttctcgagg ttaactcctt tgtttataga taaatgttga atagtttagt aagtcaatac
     3481 aaagtatttt ttcttcccac gacggataac agtcagttca ttttctaact tatcagcgtc
     3541 actcaagaca tagtcaaggt cttggatgcg gtcgccgttt acgtagatgg ctccgttttg
     3601 gacgtcttca cgggcttggc gttttgagtt aactatacca gatgagacga gcagttccac
     3661 gatattgttg ttttcgtctg cctgtacttg gtagtttggc acaccacgaa gtccttgttt
     3721 gagctctttg acagaaaggt ttttgatgtt tcctgcaaag agttgctcag tgatgttaag
     3781 tgcttctttg taggcttctt ctccgtgaac aagtgtaaca acttcacgag ccaagacttt
     3841 ttgagccaag cgttcgtgtg gcgctgcttc aaattgttta cgaatatctt caatctcatc
     3901 aagtgacaag aaagtaaaga ttttcaagaa gcgaacagcg tcagcgtcca tcacgttcat
     3961 ccagaattgg tacatttcgt atggagaagt cttttcggga ttgagccaga cggcatttcc
     4021 ttctgattta ccaaattttt taccagttgc atctgtgatt agtggaacag tgataacgtg
     4081 accagtcttg tccgccttac gacgaagcaa ttcggtacca gctgtcatat ttccccactg
     4141 gtcagaacca ccgatttgaa gagtgacatt atggtcttgg ttaaggacga agaagtcgta
     4201 cccttgcatg atttggtaag cgaactcagt gtaagaaatt cctgtttcga tccgtttttt
     4261 aacagattcc ttactcatca tgtagttgac cgtgaagtat tttccaatat cacggaggaa
     4321 gtcaatgaag ctgatgctgc caaaccagtc gtagttgttg accatgacag ccttgttttc
     4381 gccattttca aagtcaagaa aacgagaaag ttgtccttgg atagacttga cccagccatc
     4441 tactgtgtct tttgtttgga gactacgttc agcatctttg aaggacggat ctccgatgag
     4501 acctgtagca ccgccaacga gcgcataagg tttgtgacct gctagttgca agcgacgact
     4561 tgtcaagatt gcgacaaggt ggcctaggtg aaggctgtca gcagttggat cgtagccagt
     4621 ataataagaa acttgacctt cttctagggc tttacgcaaa gcttcttcat cagtcgtttg
     4681 aaatatcaaa ccacgctctt ttagctcatc aaaaatgtgc atgtgtcttt tctccttttt
     4741 aaaattattg tttctaccta ttgtatcaca aacttgggca atagcctagc agaataggga
     4801 agaaagtggc tattttattg aaaatttccc ttttgtggta taatagataa agtgaggaaa
     4861 tccatgcaaa atcaattaaa tgaattaaaa cgaaaaatgc tggaattttt ccagcaaaaa
     4921 caaaaaaata aaaaatcagc tagacctggc aagaaaggtt caagtaccaa aaaatctaaa
     4981 accttagata agtcagccat tttcccagct attttactga gtataaaagc cttatttaac
     5041 ttactctttg tactcggttt tctaggagga atgttgggag ttgggattgc tttggggtac
     5101 ggagtggcct tatttgacaa ggttcgggtg cctcagacag aagaattggt gaatcaggtc
     5161 aaggacatct cttctatttc agagattacc tattcggacg ggacggtgat tgcttccata
     5221 gagagtgatt tgttgcgcac ttctatctca tctgagcaaa tttcggaaaa tctgaagaag
     5281 gctatcattg cgacagaaga tgaacacttt aaagaacata agggtgtagt acccaaggcg
     5341 gtgattcgtg cgaccttggg gaaatttgta ggtttgggtt cctctagtgg gggttcaacc
     5401 ttgacccagc aactaattaa acagcaggtg gttggggatg cgccgacctt ggctcgtaag
     5461 gcggcagaga ttgtggatgc tcttgccttg gaacgcgcca tgaataaaga tgagatttta
     5521 acgacctatc tcaatgtggc tccctttggc cgaaataata agggacagaa tattgcaggg
     5581 gctcggcaag cagctgaggg aattttcggt gtagatgcca gtcagttgac tgttcctcaa
     5641 gcagcatttt tagcaggact tccacagagt cccattactt actctcctta tgaaaatact
     5701 ggggagttga agagtgatga agacctagaa attggcttaa gacgggctaa ggcagttctt
     5761 tacagtatgt atcgtacagg tgcattaagc aaagacgagt attctcagta caaggattat
     5821 gaccttaaac aggacttttt accatcgggc acggttacag gaatttcacg agactattta
     5881 tactttacaa ctttggcaga agctcaagaa cgtatgtatg actatctagc tcagagagac
     5941 aatgtctccg ctaaggagtt gaaaaatgag gcaactcaga agttttatcg agatttggca
     6001 gccaaggaaa ttgaaaatgg tggttataag attactacta ccatagatca gaaaattcat
     6061 tctgccatgc aaagtgcggt tgctgattat ggctatcttt tagacgatgg aacaggtcgt
     6121 gtagaagtag ggaatgtctt gatggacaac caaacaggtg ctattctagg ctttgtaggt
     6181 ggtcgtaatt atcaagaaaa tcaaaataat catgcttttg ataccaaacg ttcgccagct
     6241 tctactacca agcccttgct ggcctacggt attgctattg accagggctt gatgggaagt
     6301 gaaacgattc tatctaacta tccaacaaac tttgctaatg gcaatccgat tatgtatgct
     6361 aatagcaagg gaacaggaat gatgaccttg ggagaagctc tgaactattc atggaatatc
     6421 cctgcttact ggacctatcg tatgctccgt gaaaatggtg ttgatgtcaa gggttatatg
     6481 gaaaagatgg gttacgagat tcctgagtac ggtattgaga gcttgccaat gggtggtggt
     6541 attgaagtca cagttgccca gcataccaat ggctatcaga ccttagctaa taatggagtt
     6601 tatcatcaga agcatgtgat ttcaaagatt gaagcagcag atggtagagt ggtgtatgag
     6661 tatcaggata aaccggttca agtctattca aaagctactg cgacgattat gcagggattg
     6721 ctacgagaag ttctatcttc tcgtgtgaca acaaccttca agtctaacct gacttcttta
     6781 aatcctactc tggctaatgc agattggatt gggaagactg gtacaaccaa ccaagacgaa
     6841 aatatgtggc tcatgctttc gacacctaga ttaaccctag gtggttggat tgggcatgat
     6901 gataatcatt cattgtcacg tagagcaggt tattctaata actctaatta catggctcat
     6961 ctggtaaatg cgattcagca agcttcccca agcatttggg ggaacgagcg ctttgcttta
     7021 gatcctagtg tagtgaaatc ggaagtcttg aaatcaacag gtcaaaaacc agggaaggtt
     7081 tctgttgaag gaaaagaagt agaggtcaca ggttcgactg ttaccagcta ttgggctaat
     7141 aaggcaggag cgccagcgac aagttatcgc tttgctattg gtggaagtga tgcggattat
     7201 cagaatgctt ggtctagtat tgtggggagt ctaccaactc catccagctc cagcagttca
     7261 agtagtagtt ctagcgatag cagtaactca agtactacac gaccttcttc ttcaagggcg
     7321 agacgataat tctctaaatg aagtggccaa tcaatggatt gccacttttt tcttttcgtg
     7381 ttacaataag ggtatgaatc agtatcagaa aaagattgtt aacggaaaaa tttattcgct
     7441 cctatccggc ttaatatggg gaatctgtgg aattttagga gagtacttct ttactcatta
     7501 tcaggtgtct tcgggctgga ttacctctat gcgtttgaca ctggcaggga gtcttgtact
     7561 catttggtct gcaatacaat taaaatcgca agtgctagat atttggcgag acaagaaaaa
     7621 ttacctgccc tttttagcct atgctatttt ggggattttt tcagttcagt attttttcta
     7681 tctctgtgta gaatactcaa atgctacgac agcaactatt ttacagttta ttagccctgt
     7741 ctttatcctc ttttacaatc gcttggttta tcaaaaacga gcgtcaaaaa gcgctgtttt
     7801 ctatgttttg gttgccatgc tgggtgtttg cttgatggca acaaagggag atctctctca
     7861 gttatccatg acgccgctag ctcttataac aggtttgctg agtgccatgg gtgttatgtt
     7921 taatgttatc ttgccccaac cttttgctaa gcgttatggt tttgttccta cggttgggtg
     7981 ggggatgatt ttggcaggtt tgtttagcaa tgtcctctcg ccggtttatc agctttcctt
     8041 tactcttgat atttggagta tcttgatttg cctcattatc gctttctttg gaacggcttt
     8101 tgcttttttc atttccatga aggctgtgtc cttggtttct cctttggtgg ttgccgttat
     8161 cagtgccagt gaacctctct cttctgctct cttgagtgtt ttgttcttag gattagtagt
     8221 ggattggtcc ctccttctag ctatagcctt gattatttta cccatgatat ttttgtctat
     8281 agaagaagcg aaagaaagta gataaaaagt cttttcttaa ttctaaaagt gtgctatact
     8341 agaatagtca ataaaacacg gggagatagt tgtgaagagt gtttttaggt tgtatcggta
     8401 ggggcttgct tttaccgaca gcacgtttta tctcacatcc ctaaaaaatc atacctaaaa
     8461 acagacaaaa aggtttcaaa tttgaggcct tttttggtag aataggtatc attataacga
     8521 accaggaggc acctatgact gctacaaaaa tgaacgctca agaaattatc caatttatcg
     8581 ccaatgctga aaagaaaacc agtgtcaaag taacctttga ggggcaactc gcaactgctg
     8641 tgcctagctc tgttgtcaaa ctaggaaatg tcctattcgg agactggaag gacgtggctc
     8701 cgcttcttga aggtttggta gaaaatcaag attatgttgt cgagcaagat gctcgtaatt
     8761 ctgcagttcc tttgctagat aagcgtgcta tcaacgctcg tatcgagcca ggtgctatta
     8821 tccgtgacca ggtggaaatt ggtgacaatg ctgttatcat gatgggagct gttatcaata
     8881 tcggtgctga aatcggtgct ggaaccatga ttgacatggg tgccatcctt ggtggccgtg
     8941 ccatcgttgg aaaaaatagc cacgttggtg caggtgcagt tttggcaggt gtgattgagc
     9001 cagctagtgc tgaaccagtc cgtgtcggag acaatgttct tatcggtgct aatgcagtgg
     9061 ttatcgaagg agtccaaatc ggtagtggtt cagttgtcgc tgcaggagct atcgttaccc
     9121 aagatgtccc agaaaacgtg gtagtagcag gtgttccagc tcgtatcatc aaagaaattg
     9181 atgaccaaac ccaacaaaaa acagcgctag aggatgcgct tcgtactttg taattgtaaa
     9241 agtaaaaaag aggcggaacc ctttttccag cctctttctg ctatatcgga ggacagatag
     9301 atgttagatt tgattcagac tagacgagct ttacaccaga ttccagagat tggcttggag
     9361 gagttcaaga ctcaggctta tttgctggat gtgattgaga aattgactac gggcaaggat
     9421 tttgttcaaa ttcgtacttg gcggacaggg attttggtct acctgcaggg aagtcagccg
     9481 gagcgaacca ttggttggcg gacagatatt gatggcctgc ctatcgtcga acaaacaggt
     9541 ctaccttttg cttctcaaca ccaaggtcgc atgcatgcct gtggccatga ttttcatatg
     9601 accattgcct taggctgtct tgagcgcgcc cttgaggagc aacccaagaa taatctgctc
     9661 tttctatttc agcctgctga agaaaatgaa gctggtggta tgctcatgta tgaggacggt
     9721 gcttttggag attggttgcc aaaccaattc tatggtctcc atgttcgtcc agatttgaaa
     9781 gtcggccaga ttgcgactaa tactcataca ctctttgcag gaacttgcga ggtgaagatc
     9841 cgtttcaaag gcaaaggtgg ccacgcagct tttcctcatg aagccaatga cgccttggtg
     9901 gcggctagtt actttgtgac ccaagtgcag tcagttgtta gccgcaatgt caacccaatc
     9961 gagggagcag tggtgacctt cggcgttttt caagctggaa ccaccaacaa tgtcatcaca
    10021 gacacagctt ttttacatgg aactattcgt gccttgacac aggacatgag tctcttggtg
    10081 caaaagaggg taaaaacagt tgcagaaggg gttgcagctg cctttgatat ggaagtcgaa
    10141 gtggaactca aacaaggtgg atacctacct gttgagaaca atccagcctt ggcgcgtgaa
    10201 ctgatggact tctttgacga aaaagacgga atcgagttga ttgatatcga acctgctatg
    10261 acaggcgagg actttggtta tctcctttca aaggttgatg gcgtgatgtt ttggctaggt
    10321 atcgatagtc cctacgctct tcatcaccct caaatgagtc ctaaggaaga agtcttagct
    10381 attggggtgg ctgcggtgtc tagtttcctg aaaaagaagg cagcagaata gagggcttgt
    10441 ctatgaaatc ggaattacgc aagcaagtct tgcatgaaat gaaggcttta tctcaagaac
    10501 aaaaacaggc tatagaccaa gctttaaccg agcgaatttt acaacacccc ttttatcaag
    10561 aagccaaggt catcgcaacc tacctctctt tttctcatga gtttcaaacg cgggaactga
    10621 ttgagcaggc gctgaaggac ggcaagaagg ttttaatacc caaaacttat cccaaggggc
    10681 gcatggactt tgtagtctat gatccgcagc agttggtaaa aactgccttt gccttactgg
    10741 agccacaggg agatttggaa gtggtggatg tatctcagat tgatttgatt catgttcctg
    10801 gcctggcttt tacgacggat ggatatcgga ttggatatgg tggaggttat tatgaccgct
    10861 atctggaaca tttttctggt catactttga gtacggttca tccttgtcaa attcaggact
    10921 ttatacctga aaaccatgat attcctgttc aggaggtatt aattgatgaa ggaaatcttt
    10981 gatagacgtt accctgtgac gagtttcttc ctcttagtga cggccttggt atttttacta
    11041 atgttggtca ctgcaggcgg aaactttgac agggcagata cattatttcg atttggagcc
    11101 atgtatgggc cagctattcg cctctttccc gagcaggttt ggcgtctctt gtctgccatt
    11161 tttgttcata ttgggtggga acatttcatt gttaatatgc tttcacttta ttatcttgga
    11221 aggcaggtag aggagatttt cggttctaag cagtttttct ttctctatct tttatcagga
    11281 atgatgggca atctctttgt ttttgtattt agtcctaaat ccttagcagc aggcgcctct
    11341 acctctcttt atgggctatt tgccgcgatt attgttcttc gctatgcaac tcgcaatcct
    11401 tatattcaac agctagggca atcctatctg acactttttg tggttaacat tattggaagt
    11461 gttctgattc caggaatcag cctagcaggc catatcggtg gtgcagttgg tggcgcattt
    11521 ctagcagtta tctttccagt tagaggagaa aaacggatgt ataataccag ccagagatta
    11581 ggagcggtag tcttgttcgt aggactcgcc attttgcttt tctacaaggg aatgggaatg
    11641 tgacgaagtt gaaagaaaat ttgtgtaatg aaaaaagata aggcattttt tgaaccttat
    11701 ctttttattt tattttattc cttctcagtc aattcttttc caagttggat gaggtaattc
    11761 ttcaaatcat ctttgacttg tgggtgtttg agggcgtagt cgatggatgt tttcatgaag
    11821 ccaaacttgt ctccgacatc gtaacgagcc ccattgaact cacgagcaaa tacacgttgt
    11881 gttttattga gggtgtcgat tgcatctgtc agctgaattt catttcctgc acctggagct
    11941 tggttttcga ggatttggaa aatttcaggc gtgaggaggt agcgtccgat aatagcaagg
    12001 tcgctaggag cgtcctctgg agctggtttt tcaacaaagg tttcaacact gtaaagacca
    12061 tcttttcctt cgccttgcgg agcaataacc ccgtaagcag atacttcgtc atgagggact
    12121 ggcatgacag cgatagtaga cgcgtgggta cgctcgtagt catccatgag ttgtttggta
    12181 agtggaacag ccttttcgtc tgtgatatcc atcaagtcat caccaagcat aacgacaaaa
    12241 ggttcatttc cgacgaaagc cttggcttgc aaaacagcat ctccgagacc gcgtggatga
    12301 gtttggcgga taaaatgcag ccgcatgtca gttgttttat caactagctt caaaagatct
    12361 gttttccctt tttctttgag gttatattcc aattcgaagt ttgaatcaaa gtggtcctca
    12421 atagaacgtt ttgatttacc agtgacaact agaatatctt caatacctga tttgagagct
    12481 tcttccacga taaactggat agttggtttg tctacgattg gcaacatttc tttggcaagg
    12541 gccttggttg ctggtaaaaa tcgagttcct agtccagcag cagggatgac tgcctttcta
    12601 acttttgatg tcataaaaat cctttctata gagggttaag accactcatt ttctgcttta
    12661 aattcattgt tcatgatgtc ataaatggca tctttgatat tggttccgtg ataaataact
    12721 tggtaaatag cctgtgtaat gggcatatag actccaagtt cttgggctag ttcataggct
    12781 gctcgagtcg ttgaaattcc ttcgattacc atgcccatat tagcttctat atcagctagg
    12841 gattctcctc gtccgagagc atctccagct ctccagttac gagagtggat ggaagttccc
    12901 gttacgatca aatctcccac accagataag ccgctatagg tcaatggact ggccccgagt
    12961 gctaccccta ggcgggtgat ttctgctaaa cctcgagcga tgatggctgc cttagcatta
    13021 tcaccaaatc caagaccatg taaagctcca gcaccgacag caataatatt tttaagagca
    13081 ccagcagttt caaccccgat aacatccgta ttggtataaa gtcggaagta gtgattacta
    13141 aatagcttct gaacgtattg agctgtttgt aaatctttag aagcagcagt tattaaagtt
    13201 aggtcacgca caatggtctc ttctgcatga ctaggccctg aaacaacgac gatatcacta
    13261 cggagatgtt caggaatttc ttcttcaaga atggttgata atcgtttatg gctatcaggt
    13321 tctaatccct ttgatgcgtg catgatgata accttatggt ccaaggtttg tgcaacttgc
    13381 tgggcaacaa gtcgtgtcac ttttgttggg acaacaaaca aaatcgcatc cacatctttc
    13441 aatgtttctg ctaagtcggt gtaggcaatg atattttcgt ctagaacgac atctttaaag
    13501 tagtgcttat tagtatggtg tgtattaatt tcattgattt gctcgggaag atttccccaa
    13561 atacgtacct cgtgtccatt gtcatttaag acttgtgaaa gggcggttcc ccaagaacca
    13621 ggccccaaga cggcgacggt ttgtttttcc atgatttcct ccttgataga gttctttctc
    13681 ttattctatc atattctagg ggattttgca cttgcattac tggggtatgg tggaaaaata
    13741 cacaaaaacc gagacgaagg gataaactct tagtctttag ttaaagtgag aagaaatctg
    13801 atagatagtt tgattcagta tatgcttata atagaggtaa acaactcagg aggttcttgt
    13861 aggttgcgag agtttggcga aaaaattaaa agattacgtt tggctaaaaa aatcagtcgt
    13921 tcagaatttt gtggtgatga gtctgaatta agtatccgtc aattaattag aattgaaaat
    13981 ggagaatcca gaccaatact aacaaagtta aaatatattg ctgaacgttt ggaggttgaa
    14041 gattacaagt tgatgccaag ttatatagag ttggataagg aatacctaga attgaagtat
    14101 ttcttgatga ggactcctac atacgaagat gaaactatcg cccaaaagaa agagagtgtt
    14161 ttgataagat ttttgaagag tattatgata ggctacctga ggaagaaaga tttatcatcc
    14221 caaattattc atatctggca ctaacgaact acacagttca aaaattacca gaaaagctag
    14281 ttgaaatact gtccttctgg tgattttgct taatttctga tgttcgagac ataattgagg
    14341 agatttgtct tgattttttc ctaaaaaagg gcagactcct cccttggttt gatgctcgat
    14401 ttttaaaata aggtgactta ttctgttagg catgttttcc cctgccctct agctctatat
    14461 ggaacaggga gtatcagatt tatctggcag attgtatcaa ataaggcttg aaactgtttt
    14521 gaataggcat atagacttga gaatttgaga atatgtcgtc tagcagtaga gacatatttt
    14581 ccggcaatat gaaggaagag acgtcgaaaa cgcttgatag tcaaggcctt tacttcatca
    14641 ccagctagct gctttaaaaa gaggtagaga ttataagcca gacagcccat catcatacgt
    14701 acttcattct taatcatggt cgaactatct gtcttatccc caaagaatcc tgctttcctt
    14761 tctttgataa agttttcagc attccctcgt tcacgataga attgaaacag ctcctcacta
    14821 tctacactgc ttaaattggt caaatgaact tttttacaac cataaaaaag agcacttaat
    14881 cgtactcttc tcttttaagg attagttgaa ttaattcaaa tccactagtt ctcctgtttc
    14941 taggtagact aggcgttcac aaatgttagc aatgtaatca gcgaagcgtt ccagatgccc
    15001 tatgatataa aggtattgtg ttccattggg aattgaggtt tcttggtctt tcataagtcc
    15061 aatgatttcc tttgataagg cataataata ttggtcaatc tgttcatctt tttgagcaat
    15121 actaatagct tttgaggctt ggtgcaaagg aaaggcaacc aataaatcgg atagcatgct
    15181 gagggataat ttacccattt ggtgtaactg ttcttcgtca ggggctagtt gattttcttt
    15241 tagttgcaaa acagctttag caatgcctgc catatggtct cccatacgtt caaggtctga
    15301 acaagaagac atgatgctaa tcacaaatcg aaggtcagac acttgtggct gctgcaaggc
    15361 caacaaacgg gcacaggtca attcgatagc gctttgacct tggttgatag catgatcctt
    15421 attgataatt agctctgcca tctccttgtc tttggaggct aaggccagta aggtttttga
    15481 agctgtttca aggacaagtt gccctagtcc taaaaaggat tgttctaatt catgcaattc
    15541 taagtcaaat tgatttctca taggtttttc cttccttatc cgaaccgtcc tgaaatatag
    15601 tcttctgtgc gctgatcttt tggattggta aacacgtcaa cggtgtctcc aaattcgcaa
    15661 atttctcctg ttaagaaaaa agcagtttta tctgaaatac gtgaagcttg ttgcatgtta
    15721 tgggtaacaa tgataatcgt ataatccttt tttagttgct gaatgaggtc ttcaattttt
    15781 aaagtggaga tagggtctaa ggctgaagtc ggctcatcca ttaacagaac atcaggttct
    15841 actgctaaag ctcgcgcaat gcaaaggcgt tgctgctgac cgcctgataa ggacatggca
    15901 ctctttttaa gattatcttt gacttcgtcc caaatggctg ccccttttaa agatttttcc
    15961 actaaggcat ctaattgttt tttgtctcga ataccatgtg tccttggacc ataagccacg
    16021 ttatcataga tagacatggc aaagggatta ggctgttgaa aaaccatccc tacacgcttg
    16081 cgtagctgat taaggttgaa tttgctacta taaatatctt gctcatctaa gaggacttgg
    16141 ccttcaatat ggcaagaagg aaccaaatcg ttcatccgat taagggtttt tagaaaagtt
    16201 gatttgccac aaccagatgg gcctatcaag gcagtaatct gtctttctgg taattgaatc
    16261 gaaatatttt ttaaggcttg aaaatccccg taaaataagt ctaggtgtct gactgaaaat
    16321 gttcccatac taggaagctc ctttcacaag tttccgagat aataagcttg atagagtatt
    16381 tatcattaaa acagtaataa ttaaaatcac gccggtagca taggcttcat tgacatgtag
    16441 cccctcactt gacagcatat acatatgtag ggctagagaa cggcctgaag acatgagact
    16501 acttggcgta ttggtagagg tacctaatgt atacatgagg gcagctgttt caccaacgat
    16561 acggccaata gctagtatca ctccagctaa aatacctggc atggcaactg gtagaacaat
    16621 tctaaaaaca gtccgtaact tacctgcccc aagtccataa cttgcttgac gcatgctatc
    16681 actaacagat aaaagggctt cttctgttga gcgaataatg actggcaaca ccatgataac
    16741 tgaggttaag attcctgata acagagagta ttgaaaacct aagaagacta caaagaagag
    16801 catgccaaac agaccaaaaa caatggaagg aatcccagac aaggtatctg aggccaatcg
    16861 catgatttta acacaaaggg aatctttttt tgtatattcc acaagataaa aaccagcaaa
    16921 aatccctatg ggcaaagcta aaagaagagc accaaaaacc agaataacgg tggaaataat
    16981 cgctggcata agggaaatgt tctcagaagt ataagtccaa gaaaagaggg atagacttag
    17041 atgaggtaag cctttgatga ggataaaacc aatgattaaa aagagagagc caaaggttaa
    17101 agctgaaaaa caataaacga gaagttttag caggtattta ctcataagat gattttcctt
    17161 tcaagtaggc aaagtaggca ttaatcaaga gaataaggaa aaagagaact gctgaggttg
    17221 caataagggc ttccctatgc tgacctgatg cgtaagccat ttccagaaca atattggttg
    17281 ttaaggttct ggttcctgaa aagagtccac ttggaataat tggctggttg cctgccacca
    17341 aaataactgc catggtttca cctactgcgc gaccgattcc taaaataact gctgataaaa
    17401 taccagatct cgcagctggc aagatgacac taaaaatact ccgttcatga ctagctccta
    17461 gagccaagct accagaataa tacgttttgg gaactgttcg gatagcagat tctgacaaac
    17521 tgataatggt tggcaaaatc attattccta atagtaacga agcggttagg acactcatgc
    17581 catttcctaa aaaggttcta atccaaggca ccaataattg taggccgaaa aaaccataaa
    17641 caatagatgg aatggctgcc atcaagttga tagctgattt taagaagcca tagacgggct
    17701 ttggacaata ataaaccata aacaccgatg tcaagatgcc tgttggcacc ccaatcacaa
    17761 tcgctcctaa ggtaattaat aaggaaccaa cgatcattgg taaaatacca tagcttgccg
    17821 gaatgttcgt tggcgaccaa tcactgccta ataaaaaacg ggcaaagccg tagttagcca
    17881 tgaaaggtaa gccattacta aaaataaaga aacagattag caaaatagct acaacagcta
    17941 ctgttgcact catgaaaaaa attgccctaa aaactgcttc tttgaaggct tgttttgtca
    18001 catcttgtcc tttctagtga agaaagtaag ggagatacga cacctcccta cttgccttct
    18061 ttatcttatt gtacgatgaa acgtctgcat ctctttagag atttatggag caaacatttt
    18121 atttaatctt gtcccaggtg gttaatttgc cactaaaaac gtctgcaagt tcagccatac
    18181 tgacttggct tgccttattg tcattattga ccacaacagc aataccgtct aaagcaatag
    18241 catcatgggt gagactctta ccttcttcag gagttaattc cctagaaacc ataccaatat
    18301 cagcggtttt ctccttaaca gcggtaatac ctgctgaaga cccattagag gtaatatcaa
    18361 tcgtaacttc tggattttct tttttataag cttctgctaa tttttccatt aaagaagata
    18421 ctgaagtgga acctacaaca gacaacttgc ctgataagtg ttggcttgta tattctgtgg
    18481 tttcagtttt agcttcaata aatttattat ctgtgaccac ttgttgacct tgtttggagt
    18541 ggataaagct gataaaatct tgacctagct tggaaagatt agaagaccaa acaatgttga
    18601 agggacgttg aagagggtat tcaccatcta aaactgtgtc tcgactagcc ttgacaccat
    18661 caatctctaa agccttgaca gatttcgtta aagatcccaa ggagatgtag ccgatagcat
    18721 tagcattccc ttgaactgct gagagaacac cttctgtact attttgaatc acagctgttt
    18781 tggcagtgtt gtcaattttt ttatcaccgt cttttttgag aatccctgtg atttctgtga
    18841 aggcaccccg tgtcccagag ccattttctc gtgaaatcac ctcaatcgtt cctgaagctg
    18901 actgtttgga agtagctgac tgattgccac aggcaacaag cccaaatcct gataagccaa
    18961 tggctgcaag agtaagtatt tttttgaatt tcataataat cacctttatc tctatgtatt
    19021 tttcttgtgt aggcttacta catttatagt ctaacaagtc tttgtaaagg tttatccctg
    19081 attcatgtaa agattgtgta aagaatcaaa aaaagccact tttgaaaaat ggctgctcct
    19141 aaaaatagct ttaaaaatta ttagtcctgt gcgaaagatt ggttaggaag aaaaatcgtg
    19201 aagcaactgc ctctgccaag ctgactcgtc accgtgactt ggccacctaa taattgactg
    19261 agttctttga caatggcaag gccaagacca gtgccaccag tttgtctgct tcgaccttta
    19321 ttaactcggt aaaaacgttc aaaaatacga tcctgctcta attgactaat accaatccct
    19381 gtatctgata cagaaatctt aatgccttcg ttcacctttt gggtcttgac ctcaattttt
    19441 cccccttgtt cagtgtaacg gatggcattg gataaaagat tgagtaagat ttgggaaagt
    19501 aattgactat ctgatacgag ggtgacatca tctggcacct gcacctttag ctgtaaatcc
    19561 ttcttcttga gctgaggttg caagctttga gtcaaatcct gtacaaattc tgccaaagaa
    19621 agggtcgtcc attgtatagg catttgttga gccttagata aggtaagaag atgctcaaca
    19681 atatgctcaa gacgcaagct ttctttgtaa ataatgtcta gaaagtcatc cttgagcgct
    19741 tcttcttcag ctgacatccc cttaatggtt tcagcaaagc ccttaatcga agtaactggt
    19801 gtcctcaatt catgggaggc atttgagaca aaggctaaat ttaacttttc ataagttcta
    19861 atcgttgtta aatcatatag caagacgagc acagcttcca cagattgggt ggggctaaaa
    19921 acgggaactg ctgtcacttc taaaatcaag tcaccctcat gaaacccact tacttcttgt
    19981 tttaaccttg ttttttgatc aaaggcttgg tgaactaaat tccgaatatc catccgtttg
    20041 aggtcatcaa gtgaacttat gtcgccgtcc acatcgggaa aataatgagg cagagagcga
    20101 ctggataata acatctgacc ttgagcggaa actaaaaacg tccccatggt taggtgcgac
    20161 agaagaacct ccattgtttc ggctaggtcc ttgtattgct gatcctgttg ggagactttg
    20221 gtttttaggc cagacacata ctgagccaaa gactttaagt cttcttgccc tttttctaaa
    20281 aagtattcac tactggtcaa gagaggttgg tgcaaggtct caaaagcaac ttcccatttc
    20341 caaaggcaaa agagccagta gccacctagt cccaaagaaa gggctagaag aaagagaccg
    20401 atgcctttac tgatccaagt taatgccatc cctgcaatca gaatgaggct aacacttaga
    20461 ttgactagcc aaaattgaag gtagcgtttc atctataact ccttgaactt ataaccataa
    20521 ccccgaatgg ttcgaataaa ttgaggggct ttaggattgt cttcaatttt ttccctcaac
    20581 ttaccaatat gaacgtccac caaacgtgtt tcctgcccaa agtcataccc ccagatacgt
    20641 tccaaaagac gctctctagt cagtgtcatg ttgggatgtt tcataagata gagcaagagt
    20701 tcaaattctt ttggggtcaa actcagtaac ttattcgcct tgtagacttc atgacgctca
    20761 gggtatactt tcaaggtccc aaatagccaa gaattgtcag cgatattatc tgaatcatct
    20821 ccttcttgtt ttcctttagt tcgcctgagg acagccttga cacgcgccag taattctcta
    20881 gggctaaaag gcttggtcag gtagtcatca gcccctaatt ccaaggccaa aaccttatca
    20941 aattcatcac ttttcgcaga aaccatcata attggagttt tgacgccttt ggctctcagc
    21001 cgcttacaaa cttctatgcc atctaattgt ggtaacatga tatcaagcaa gataaaatca
    21061 aagggttctg tttctgccaa agctaaggcc ttccgtccat ttgttaccaa ttgagtagaa
    21121 aagccttcct tacttaaatg gtagtcaagc aatttcagaa tgtgttcttc atcatccact
    21181 aataagactt gttttgtcat ctattatctc ctattggtaa cattataaca caattatcag
    21241 aaatcctaac attgctaaat cagattaaat ttgcttatca agactagtat ctggtcaaac
    21301 gctcaatcat ctccttgtgc tctggatagg tcgccagtag atctaccctt tcaaataatt
    21361 caaaatcctc aaattcaaaa ccaggagcaa caagacaaga aaccagagca tcatccttat
    21421 caactgttga tccccaaata gtgcccttag gaacacagta gtgaagttgt tgccctttgg
    21481 atatgtccag gcctaaagtg actgcttcgt agtgaccatc tgctgtaatc atgtgaacag
    21541 taagtgggga ttctgcatga aaataccaga tttcatctgc tgtcaatcgg tgaaaatgtg
    21601 aaggattcgt ttcttctaat aagaaataaa tactggtata aagcgccctt cccttaccag
    21661 caaggtttat agtgtctgaa gctttttttg tttgtctaaa atagccacct tcaacatggg
    21721 gagctaactc tagagttctt atcaagtctt ctttatccgt cggagccaat gggttgaagt
    21781 aactcttgtt caaagtggtt ttacgatttc aagaactcct ctcagttctg aggacacggt
    21841 aatgattgat gcgacggaag tacaaatcaa tcgccctaaa agaagaatta gcgaatgatt
    21901 ctggtaaaaa gaaatgccac gctatgaagg ctcaagcgat tgtcacaagt caagggagaa
    21961 ttgtttcttt ggatatcgct gtgaactatt gtcatgatat gaagttgttc aaaatgagtc
    22021 gcagaaatat cggacaagct ggtaaaatct tggctgacag tggttatcaa gggctcatga
    22081 agatatatcc tcaagcacaa actccacgta aatccagcaa actcaagcca ctaacagttg
    22141 aagatcaagc ctataaccat gcgctatcca aggagagaag caaggtcgag aacatctttg
    22201 ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg aaatcatcgt aaacgcttcg
    22261 gattacgaat gaatttgatt gctggtatta tcaatcatga actaggattc tagttttgca
    22321 ggaagtctat tatttggtta ggtgaattag tgaagcgttt aggcaagtgt ctctggttac
    22381 gacgtcatgg cctctaaatc gattatattt aggggtcatg actagtgaag cagttagcta
    22441 gttcgcatat aagcggctag cgtctaacaa ttaggaactt tagttccaat aactttaaga
    22501 ttacgacgtt ttaggacata aatcgatcat atttatgtcc taaaactagt gaagcgccta
    22561 gccaaagtcc gaataggatt tggcgttagt tacttagatt gctttgcaat caagtaactt
    22621 tggcgattta catcttctct ggcgcttcta ctccaagcaa gcgaagggct tcttttagaa
    22681 cgactgcggt tgcgtagctg agggctagac ggctgtcgcg ttctgggctt tcatccaaga
    22741 tacgtgtatg tgcatagtat ttgttaaagg attgagctag gctaattgca aatttagcaa
    22801 tgatagaagg ttcaaagtta tctgccgcac ggttgataat acgtgggaag tcttgaatga
    22861 gtttaatgat ttcccagctt tcagtatcat tcaagctata gttgccagct gtttctggtt
    22921 tgaaatcggc tttgcgtaag atagattgga tacgagcgta ggcatattga acgtaaggtc
    22981 cagtttcacc ctcgaaggat accatagctt ctaggtcgaa gtcgtatcca tttgtacggt
    23041 cggttttgag gtcatagaat ttaatggctc caaccccaac agcatgtgct acttggtctt
    23101 tgttttctag ttcaggattt ttagcctcga tttggacctt ggcacggcta acagcctctg
    23161 caacagtagg ctctagcaag atgacattcc ctttacgagt agagagcttc ttcccttctt
    23221 ttgtaaccag accaaaagga acgtgggtaa tgtcgtcact ccaatcgtag cccatctctt
    23281 gcaagacagc tttgagctgt ttaaagtggg cagattgttc ttgaccaacg acatagatag
    23341 atttagcaaa ttggtattcg tttttacggt agagggctgc agccaagtca cgtgtgatat
    23401 agagagttgc accatcagac ttcttgatga gggctggatg ttcaattcca tatttctcaa
    23461 gattcacaac ttgggcacct tctgattcaa gaagtagtcc tttttcagaa agaatgtcta
    23521 caactgcatc catcttatca ttgtagaagg cttctccgtt atagctgtca aattcaacct
    23581 tcaattcatt gtaaaggcgg ttaaattcca ctaaactttc atcgcggaac cattgccaaa
    23641 gagcgagagc ttcctcatct ccattttcaa gtttacggaa ccattcgcgc gcttcttcat
    23701 ccaagctagg gtcattttca gcttcagcgt tgatgcggac atagagttta aggagttcat
    23761 cgattggatg agcttttaca gcttcttcgt cgccccattt tttgtaggca acaatcaaca
    23821 tcccaaattg tttaccccag tctcccaaat ggttgacctt gaccgtttga taaccgattt
    23881 tttggaaaat atgtgacaag ctatctccga taacagttga acgcaggtgg ccaatagaaa
    23941 atggtttagc gatattcgga ctagacatgt cgataacaac attttcttgt ttgccaatat
    24001 tttggtcagc atagtgttct ttttcagtgg taacagcttg caatacttga gcagaaatgg
    24061 cagatttatc aaggaaaaag ttaacgtaag gtcctgttgc gacaactttt tcaaaggctt
    24121 ggctgttcat tttttcagcc agttcagccg caatcatttg tggtgcttta cgttcgactt
    24181 ttgcaagaga aaaagcaggg aaagcaatgt ctcccatttc tgagttttta ggggtttcca
    24241 gtaactttaa aatagcctct tggtccaggc tatcaatgat gctagataat tcgctagcaa
    24301 tcaattcttt tgtattcatt aagagctcct ttttggactt ttctactatt ttatcacaat
    24361 tttaaagaaa gaagaaaaaa tttttgaaat ctcctgtttt tttggtataa tatggttata
    24421 aatatagtta taaatatgca cgcaagagga ttttatgaga aaaagagatc gtcatcagtt
    24481 aataaaaaaa atgattactg aggagaaatt aagtacacaa aaagaaattc aagatcggtt
    24541 ggaggcgcac aatgtttgtg tgacgcagac aaccttgtct cgtgatttgc gcgaaatcgg
    24601 cttgaccaag gtcaagaaaa atgatatggt gtattatgta ctagtaaatg agacagaaaa
    24661 gattgatttg gtggaatttt tgtctcatca tttagaaggt gttgcaagag cagagtttac
    24721 cttggtgctt cataccaaat tgggagaagc ctctgttttg gcaaatattg tagatgtaaa
    24781 caaggatgaa tggattttag gaacagttgc tggtgccaat accttattgg ttatttgtcg
    24841 agatcagcac gttgccaaac tcatggaaga tcgtttgcta gatttgatga aagataagta
    24901 aggtcttggg agttgctctc aagacttatt tttgaaaagg agagacagaa aatggcgata
    24961 gaaaagttat cacccggcat gcaacagtat gtggatatta aaaagcaata tccagatgct
    25021 tttttgctct ttcggatggg tgatttttat gaattatttt atgaggatgc ggtcaatgct
    25081 gcgcagattc tggaaatttc cttaacgagt cgcaacaaga atgccgacaa tccgatccct
    25141 atggcgggtg ttccctatca ttctgcccaa cagtatatcg atgtcttgat tgagcagggt
    25201 tataaggtgg ctatcgcaga gcagatggaa gatcctaaac aagcagttgg ggttgttaaa
    25261 cgagaggttg ttcaggtcat tacgccaggg acagtggtcg atagcagtaa gccggacagt
    25321 cagaataatt ttttggtttc catagaccgc gaaggcaatc aatttggcct agcttatatg
    25381 gatttggtga cgggtgactt ttatgtgaca ggtcttttgg atttcacgct ggtttgtggg
    25441 gaaatccgta acctcaaggc tcgagaagtg gtgttgggtt atgacttgtc tgaggaagaa
    25501 gaacaaatcc tcagccgcca gatgaatctg gtactctctt atgaaaaaga aagctttgaa
    25561 gaccttcatt tattggattt gcgattggca acggtggagc aaacggcatc tagtaagctg
    25621 ctccagtatg ttcatcggac tcagatgagg gaattgaacc acctcaaacc tgttatccgc
    25681 tacgaaatta aggatttctt gcagatggat tatgcgacca aggctagtct ggatttggtt
    25741 gagaatgctc gctcaggtaa gaaacaaggc agtcttttct ggcttttgga tgaaaccaaa
    25801 acggctatgg ggatgcgtct cttgcgttct tggattcatc gccccttgat tgataaggaa
    25861 cgaatcgtcc aacgtcaaga agtagtgcag gtctttctcg accatttctt tgagcgtagt
    25921 gacttgacag acagtctcaa gggtgtttat gacattgagc gcttggctag tcgtgtttct
    25981 tttggcaaaa ccaatccaaa ggatctcttg cagttggcga ctaccttgtc tagtgtgcca
    26041 cggattcgtg cgattttaga agggatggag caacctactc tagcctatct catcgcacaa
    26101 ctggatgcaa tccctgagtt ggagagtttg attagcgcag cgattgctcc tgaagctcct
    26161 catgtgatta cagatggggg aattatccgg actggatttg atgagacttt agacaagtat
    26221 cgttgcgttc tcagagaagg gactagctgg attgctgaga ttgaggctaa ggagcgagaa
    26281 aactctggta tcagcacgct caagattgac tacaataaaa aggatggcta ctattttcat
    26341 gtgaccaatt cgcaactagg aaatgtgcca gcccactttt tccgcaaggc gacgctgaaa
    26401 aactcagaac gctttggaac cgaagaatta gcccgtatcg agggagatat gcttgaggcg
    26461 cgtgagaagt cagccaacct cgaatacgaa atatttatgc gcattcgtga agaggtcggc
    26521 aagtacatcc agcgtttaca agctctagcc caaggaattg cgacggttga tgtcttacag
    26581 agtctggcgg ttgtggctga aacccagcat ttgattcgac ctgagtttgg tgacgattca
    26641 caaattgata tccggaaagg gcgccatgct gtcgttgaaa aggttatggg ggctcagacc
    26701 tatattccaa atacgattca gatggcagaa gataccagta ttcaactggt tacagggcca
    26761 aacatgagtg ggaagtctac ctatatgcgt cagttagcca tgacggcggt tatggcccag
    26821 ctgggttcct atgttcctgc tgaaagcgcc catttaccga tttttgatgc gatttttacc
    26881 cgtatcggag cagcagatga cttggtttcg ggtcagtcaa cctttatggt ggagatgatg
    26941 gaggccaata atgccatttc gcatgcgacc aagaactctc tcattctctt tgatgaattg
    27001 ggacgtggaa ctgcaactta tgacgggatg gctcttgctc agtccatcat cgaatatatc
    27061 catgagcaca tcggagctaa gaccctcttt gcgacccact accatgagtt gactagtctg
    27121 gagtctagtt tacaacactt ggtcaatgtc cacgtggcaa ctttggagca ggatgggcag
    27181 gtcaccttcc ttcacaagat tgaaccggga ccagctgata aatcctacgg tatccatgtt
    27241 gccaagattg ctggcttgcc agcagacctt ttagcaaggg cggataagat tttgactcag
    27301 ctagagaatc aaggaacaga gagtcctcct cccatgagac aaactagtgc tgtcactgaa
    27361 cagatttcac tctttgatag ggcagaagag catcctatcc tagcagaatt agctaaactg
    27421 gatgtgtata atatgacacc tatgcaggtt atgaatgtct tagtagagtt aaaacagaaa
    27481 ctataaaacc aagactcact agttaatcta gctgtatcaa ggagacttct ttgacaattc
    27541 tccacttttt tgctagaata acatcacaca aacagaatga aaaggagctg acgcattgtc
    27601 gctccctttt gtctattttt taaggagaaa gtatgctgat tcagaaaata aaaacctaca
    27661 agtggcaggc cttggcttcg ctcctgatga caggcttgat ggttgctagt tcacttctgc
    27721 aaccgcgtta tctgcaggaa gtattagacg ccctccttac tgggaaatat gaagctattt
    27781 atagtatcgg ggcttggttg attggtgtgg ccgtagtcgg tctagttgct ggtggactca
    27841 atgttgtcct cgcagcctat attgcccaag gagtttcatc cgaccttcgg gaggatgcct
    27901 tccgtaaaat tcaaaccttt tcttatgctg atattgaaca atttaatgcg ggaaatctag
    27961 tcgttcgaat gacaaatgat atcaaccaga ttcagaacgt tgtcatgatg accttccaga
    28021 ttcttttcag acttcccctc ttgttcatcg gttcgtttat cctagcggtt caaaccttac
    28081 cttctctgtg gtgggtgatt gttctcatgg tagtcttgat ttttggtttg actgctgtca
    28141 tgatgggaat gatggggcct cgttttgcca agtttcaaac ccttcttgag cgcatcaatg
    28201 ccattgccaa ggaaaattta cgtggcgttc gtgtggtcaa gtcctttgtc caagaaaaag
    28261 agcaatttgc taagtttaca gaggtctcag acgagcttct tggtcaaaac ctttacattg
    28321 gttatgcctt ttcagtagtg gaacccttta tgatgttggt tggttacggg gcggtcttcc
    28381 tctctatttg gctggtcgcg ggaatggttc agtcggatcc gtctgttgtt ggttccatcg
    28441 cttcttttgt taattaccta agccagatta tctttaccat tgttatggtt ggatttttgg
    28501 gaaattctgt cagccgtgcc atgatttcca tgcgtcgtat tcgagaaatt cttgacgcag
    28561 agccagctat gaccttcaag gatatcccag atgaagagtt ggttggaagc cttagctttg
    28621 aaaatgtgac ctttacctat ccaatggaca aggaaccgat gctgaaagat gtgagcttta
    28681 ctattgaacc tggtcaaatg gttggtgtag ttggagcgac tggtgcagga aagtcaacct
    28741 tggctcaatt gattccacgt ctctttgatc cacaggaagg ggctatcaaa atcggaggta
    28801 aggatattcg agaagtgagt gaaggaaccc tgcgtaaaac agtttccatc gttctccaac
    28861 gtgccattct ttttagtgga acgattgcag ataacttgag acaggggaag ggaaatgcta
    28921 ctctatttga aatggagcgc gcagccaata ttgcccaggc tagtgaattc attcatcgta
    28981 tggagaaaac ctttgaaagt ccagttgaag aacggggaac caatttctct ggtggacaaa
    29041 aacaaaggat gtcgattgcg cgtgggattg tcagcaatcc acgtattctg atttttgatg
    29101 attcgacctc agccttggat gccaaatcag agcgcttggt gcaagaagct ttgaataagg
    29161 acttgaaggg gacgacaacc attattattg ctcaaaaaat tagctcggtt gtccatgcag
    29221 acaagatctt ggttctaaat caaggacgat tgattggtca aggcacgcat gcagacttgg
    29281 ttgccaacaa tgccgtttac cgtgaaatct atgaaacaca gaaatgaaag acaaactata
    29341 agaaaagtca atagttttat ctaaactatt tcttatttca atttgatgat ttggcgatga
    29401 ttttagagca cggcaaaaag ctattgaaaa agtccatttt ttcaaaggta atcctgtgtt
    29461 aatttcagaa attacatcac tttttgttcg tcaaatggca gctctttttt aggatataaa
    29521 acagggttcg gataagtttt tttgcaaggt ggatgatggc tacattgtaa tgttttcctt
    29581 gttctaactt agtcttaaga taggccttaa aagcaggtga aaagcgaggg catgctttgg
    29641 cagcttgtat gagtacctac cgcagatgag gggaaccccg tttgaccatt cttcctgcta
    29701 aatcaatctg acctgactga taaatagaag aatccagtcc agcgaaagct tgtaattgag
    29761 caggattatc aaaggcatga atatttcgaa tctcggctaa aatgaccgcc cctaaacgat
    29821 tctcaatccc agtaaccgtc gtgatgaccg agttgaactc agccatcaag tcattgacac
    29881 attttttcgc cttgtcaatg agcctcttgt aatgtttgat gttttcatta caagagataa
    29941 aacgtttatg cgttatcaaa ctcattacca attgaaacaa aaagctgtgg ttagatcctt
    30001 tcggaaattg tcaagcgatt ggaggaaatg aactaatcca cagcggctta ttccaagtat
    30061 accacttggg ctttggcagt agctaactgc gctaaatata atataaggag gagtaaaatg
    30121 aagacagttc aatttttttg gcattatttt aaggtctaca agttctcatt tgtagttgtc
    30181 atcctgatga ttgttctggc gacttttgcc caagccctct ttccagtctt ttctggacaa
    30241 gcggtgacgc agctagccaa tttagttcaa gcttatcaaa atggcaatcc agaacttgta
    30301 tggcaaagcc tatcaggaat catggtcaat cttggcctgc tggttttggt tctatttatc
    30361 tctagtgtaa tatacatgtg tctcatgacg cgcgtgattg cagaatcgac caacgagatg
    30421 cgcaaaggcc tctttggtaa gcttgctcag ttgacggttt ctttctttga ccgtcgacaa
    30481 gatggcgata tcctgtctca ttttaccagt gatttggata atatcctcca agcctttaac
    30541 gaaagcttga ttcaggtcat gagcaatatt gttttataca ttggtctgat tcttgtcatg
    30601 ttttcgagaa atgtgacgct ggctctcatc accattgcca gcaccccatt ggctttcctt
    30661 atgctgattt tcatcgtgaa aatggcacgt aaatacacca acctccagca gaaagaggta
    30721 gggaagctca acgcctatat ggatgagagc atctcaggcc aaaaagccgt gattgtgcaa
    30781 ggaattcaag aggatatgat ggcaggattt cttgaacaaa atgagcgcgt gcgcaaggca
    30841 acctttaaag gaagaatgtt ctcaggaatt cttttccctg tcatgaatgg gatgagcctg
    30901 attaatacag ccatcgtcat ctttgctggt tcggctgtac ttttgaatga taagtctatt
    30961 gaaacaagta cagccctagg tttgattgtt atgtttgcac aattttcaca gcagtactac
    31021 cagcctatta tccaagttgc agcgagttgg ggaagccttc agttggcctt tactggagct
    31081 gaacgaattc aggaaatgtt tgatgcagag gaggaaatcc gacctgaaaa ggctccaacc
    31141 ttcactaagt tgcaagaaag tgttgaaatc agtcatatcg atttttcata cttgcctgat
    31201 aaacctattt tgaaagatgt cagcatttct gcccctaaag gccagatgac agcagttgtt
    31261 gggcctacag gttcaggaaa aacgactatt atgaacctca tcaatcgctt ttatgatgtt
    31321 gatgctggtg gtatttattt tgatggtaaa gacattcgtg gctatgactt agatagtctt
    31381 agaagcaagg tgggaattgt attgcaagat tcggtcttgt ttagcggaac gattcgagac
    31441 aatatccgat ttggtgtgcc agatgctaat caggaaatgg ttgaggtagc agcaaaagca
    31501 acccacattc acgactatat cgaaagtttg cctgataagt acgatactct tattgatgat
    31561 gaccagagca tcttttcaac agggcagaag caattgattt caatcgctcg aaccctgatg
    31621 acagatccag aagttctcat tctcgatgaa gcaacttcaa acgtagatac ggtgacggaa
    31681 agcaagattc agcatgccat ggaggtggtt gtagcaggta gaactagttt cgtcattgcc
    31741 caccgcttga aaaccattct caatgcagat cagattattg tccttaaaga tggagaagtc
    31801 attgaacgtg gtaaccacca tgaacttttg aagctaggtg gcttttattc agaactctat
    31861 cacaatcaat ttgttttcga ataagaaaga agttgtccta tgtgggcagc tttttcttgt
    31921 ccataaaaaa tgtttatcac agccttaaaa aaaacatatt agacgaaagt cattttgagt
    31981 gatatgatag gactatcgtt agtattcgaa aggagaggca tcatggctag aacggttgta
    32041 ggagttgctg caaatctatg tcccgtagac gcagaaggca aaatcattca ttcatctgta
    32101 tcttgtagat tcgcagagat cattcgtcaa gtcggtggtc tccctttagt cattcctgtt
    32161 ggtgatgagt cagttgtacg tgattatgtg gaaatgattg acaaactcat tttgacagga
    32221 ggccaaaatg ttcatcctca gttttatgga gagaaaaaga ccgtcgaaag cgatgattac
    32281 aatctggtcc gtgacgaatt tgaattggca ctcttgaagg aagcgcttcg tcagaataaa
    32341 ccaattatgg caatctgtcg cggtgtccaa cttgtcaatg ttgcctttgg tggaaccctc
    32401 aatcaagaaa tcgaaggtca ctggcaagga ctacctttcg ggacatctca ctctattgag
    32461 acagtagaag gaagcgtggt ggctaagcta tttgggaaag aaagtcaggt caactcagtc
    32521 catcgtcaaa gcattaaaga tttggcacct aatttccgtg taactgctat tgattcaaga
    32581 gaccaaacta ttgaagcgat tgagtctatc gacgagcacc gcattatcgg tttacagtgg
    32641 catccagagt ttctggttaa tgaagaagat ggcaatttag aattatttga gtatttattg
    32701 aatgaactgt aacgattgga acatctggtc gttctttctt ttattttttc aaaattttta
    32761 gaatgtggca ttttacgcaa acgtttgaat tctgataaaa attggagaaa ttcgacaaaa
    32821 aaacttgaaa aaaacgaagg taagcgttat gatagaaaag aagaaatatt ggaggaagaa
    32881 catgtcacat attaaatttg attattcaaa agttttagac aaatttgttg caccacatga
    32941 agtggaatac atgcaatcac aagtaacagc agcagatgaa ttgatccgta aaggaactgg
    33001 tgctggtagc gacttcttgg gatggttgga ccttcctgaa aaatacgacc gcgaagaatt
    33061 tgaccgcatc ttgaaagctg ctgagcaaat caagtcagac agcgatgttt tggttgtgat
    33121 cggtattggt ggatcttacc ttggtgcaaa agcagcaatc gacttcttga atcaccattt
    33181 tgctaacttg caaacaaaag aagaacgcaa agctccacaa atcctttacg caggaaactc
    33241 aatctcatct acttaccttg ctgacttggt agagtatgtt gcagacaaag acttctcagt
    33301 aaacgtaatt tctaaatcag gtacaacaac tgaaccagcg attgctttcc gtgtctttaa
    33361 agaactcttg gttaagaaat acggtcaaga agaagctaac aaacgtatct atgcaacaac
    33421 tgaccgccaa aagggtgctg ttaaggttga agcagacgct aacggttggg gaacatttgt
    33481 tgttccagat gatatcggtg gacgcttctc agtattgaca gccgttggtt tgcttccaat
    33541 cgcagcatca ggagctgaca taaaagctct tatggaaggt gcgaatgcag ctcgcaaaga
    33601 ctacacttca gacaaaatct ctgaaaacga agcttaccaa tacgcagctg ttcgtaacat
    33661 cctttatcgt aaaggctatg caactgagat cttggtaaac tatgagccat cacttcaata
    33721 cttctcagaa tggtggaaac aattggctgg tgaatcagaa ggaaaagacc aaaaaggtat
    33781 ctacccaact tcagccaact tctcaactga cttgcactca cttggtcaat ttatccaaga
    33841 aggaactcgt atcatgtttg aaacagttgt ccgtgttgac aaacctcgta aaaacgtgat
    33901 tattcctact ttggaagaag accttgacgg acttggttac cttcaaggaa aagacgttga
    33961 ctttgtaaac aaaaaagcaa ctgacggtgt tcttcttgcc cacacagatg gtgatgtacc
    34021 aaacatgtat gtgactcttc cagagcaaga cgctttcact cttggttaca ctatctactt
    34081 cttcgaattg gcaattgccc tttcaggtta cttgaatgct atcaacccat ttgaccaacc
    34141 aggtgttgaa gcttataaac gtaacatgtt tgcccttctt ggaaaaccag gatttgaaga
    34201 attgagcaaa gaacttaacg cacgtctata atagaagaaa agagtggttt gcccactctt
    34261 tttactctct ttatccatag aaattggact cagccaagac ttgtgatata atatagaaag
    34321 caaaaaggca gacgcctaga taataggaga aactatgtca aaagatatcc gcgtacgtta
    34381 cgcaccaagt ccaacaggac tactacacat cggaaatgcc cgtacagcat tgtttaacta
    34441 cttgtatgcg cgccatcatg gtggaacatt tctcatccgt atcgaagata ctgaccgtaa
    34501 acgccatgtc gaggatggtg aacgttcaca acttgaaaac cttcgctggt taggcatgga
    34561 ttgggatgaa agtccagaat cacatgagaa ttatcgccag tctgagcgtt tggacttgta
    34621 tcaaaaatac attgaccaac tattagctga aggaaaagcc tataaatctt acgttacaga
    34681 agaagagttg gcagctgaac gtgaacgtca agaagctgct ggtgaaacac ctcgatatat
    34741 caacgaatac cttggtatga gtgaagagga aaaagcggct tatatcgcag aacgtgaagc
    34801 agctggtatc ataccaacag ttcgtttggc tgtcaatgag tcaggtatct acaagtggca
    34861 tgatatggtc aaaggtgata tcgaatttga aggtggcaat atcggcggtg actgggttat
    34921 ccaaaagaaa gacggttacc caacttacaa ctttgccgtt gttatcgatg accacgatat
    34981 gcaaatctct catgttatcc gtggagatga ccatattgct aatacaccaa aacagcttat
    35041 ggtctatgaa gctcttggtt gggaagctcc agagtttggt cacatgacct tgattatcaa
    35101 ctctgagact ggtaagaagt tatctaaacg tgatactaat acacttcaat ttatcgaaga
    35161 ttaccgaaag aaaggttacc ttccagaagc agtctttaac tttattgctc ttcttggttg
    35221 gaacccaggt ggtgaagatg agattttctc tcgtgaagaa ctcattaaac tttttgatga
    35281 aaaccgcctc agcaagtcac cagcagcctt tgatcagaaa aaattagact ggatgagcaa
    35341 tgattatatc aagaatgcag accttgaaac catctttgaa atggcaaaac cattcttaga
    35401 ggaagcaggc cgtttgactg acaaggctga aaaattagtt gagctctata aaccacaaat
    35461 gaaatcagta gatgagatta tcccattgac agatcttttc ttctcagatt tcccagaatt
    35521 gacagaagca gagcgcgaag tcatgacggg tgaaacagtt ccaacagttc ttgaagcatt
    35581 caaagcaaaa cttgaagcga tgacagatga tgaatttgtg acagaaaata tcttcccaca
    35641 aattaaagca gtccaaaaag aaacaggtat taaagggaaa aatcttttca tgcctattcg
    35701 tatcgcagtt tcaggcgaaa tgcatgggcc agaattacca gatacaattt tcttgcttgg
    35761 acgtgaaaaa tcaattcagc atatcgaaaa cattctaaaa gaaatctcta aataaagagg
    35821 atacaataat ggacatctgg gaaaagatgt acgaagaagc acagaaacta tacaatccac
    35881 atgaagtatc agactttgtt tatgccaatc atgttgtagc tgcagtagaa gcaggagatg
    35941 gacaaatatt tacaggattc tgtatggagg gaacctgtgg tgttttccat ctctgcgcag
    36001 aacgggcggc cctcttcaat atgtaccaat tttcaggaca aactaaggtt aagaaagtat
    36061 tagcctttcg agataaacca ccttatggtg gaagttcagc catgccttgc ggtgcttgta
    36121 gagaattcct tttagagctt aatgctgaaa ataaagatgc agaattcatg atggactata
    36181 atataagaaa aacagttaaa gtctcagaac taatccctta ttggtgggga gaagaacgtg
    36241 cttctaagtt taatgagcga tagaagagtc agtataattc tggctctttt tactataagt
    36301 tgaaaaaata aaaaaaatta gaaaaagtag ttgacaaa
//
LOCUS       DAVLCS010000018        36024 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLCS010000018 DAVLCS010000000
VERSION     DAVLCS010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36024
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.018"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            914..1135
                     /locus_tag="VXC78_001037"
     CDS             914..1135
                     /locus_tag="VXC78_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0583136.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            1652..1905
                     /locus_tag="VXC78_001038"
                     /pseudo
     CDS             1652..1905
                     /locus_tag="VXC78_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            2033..3262
                     /locus_tag="VXC78_001039"
     CDS             2033..3262
                     /locus_tag="VXC78_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0583137.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFAGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            3282..5978
                     /gene="ppc"
                     /locus_tag="VXC78_001040"
     CDS             3282..5978
                     /gene="ppc"
                     /locus_tag="VXC78_001040"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0583138.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    6061..6278
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6391..7395
                     /locus_tag="VXC78_001041"
     CDS             6391..7395
                     /locus_tag="VXC78_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0583139.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            7464..8330
                     /locus_tag="VXC78_001042"
     CDS             7464..8330
                     /locus_tag="VXC78_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0583140.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            8327..9085
                     /locus_tag="VXC78_001043"
     CDS             8327..9085
                     /locus_tag="VXC78_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583141.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            9175..10935
                     /gene="dnaG"
                     /locus_tag="VXC78_001044"
     CDS             9175..10935
                     /gene="dnaG"
                     /locus_tag="VXC78_001044"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV0583142.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRAGI
                     ESAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10938..12047
                     /gene="rpoD"
                     /locus_tag="VXC78_001045"
     CDS             10938..12047
                     /gene="rpoD"
                     /locus_tag="VXC78_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV0583143.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            12061..12390
                     /locus_tag="VXC78_001046"
     CDS             12061..12390
                     /locus_tag="VXC78_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0583144.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12424..13548
                     /gene="cpoA"
                     /locus_tag="VXC78_001047"
     CDS             12424..13548
                     /gene="cpoA"
                     /locus_tag="VXC78_001047"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV0583145.1"
                     /translation="MRKFPLFSSSLSFLLLILFKENDIIVVMEKKKLRINMLSSSEKV
                     AGQGVSGAYRELVRLLHRAAKDQLIVTENLPIEADVTHFHTIDFPYYLSTFQKKRSGR
                     KIGYVHFLPATLEGSLKIPFFLKGIVKRYVFSFYNRMEHLVVVNPMFIEDLVAAGIPR
                     EKVTYIPNFVNKEKWHPLPQEEVVRLRTDLGLSDNQFIVVGAGQVQKRKGIDDFIRLA
                     EELPQITFIWAGGFSFGGMTDGYEHYKKIMENPPKNLIFPGIVSPERMRELYALADLF
                     LLPSYNELFPMTILEAASCEAPIMLRDLDLYKVILEGNYRATAGREEMKEAILEYQAN
                     PAVLKDLKEKAKNISREYSEEHLLQIWLDFYEKQAALGRK"
     gene            13564..14889
                     /locus_tag="VXC78_001048"
     CDS             13564..14889
                     /locus_tag="VXC78_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0583146.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14920..15096
                     /locus_tag="VXC78_001049"
     CDS             14920..15096
                     /locus_tag="VXC78_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0583147.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            15155..15289
                     /locus_tag="VXC78_001050"
     CDS             15155..15289
                     /locus_tag="VXC78_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV0583148.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            15353..16663
                     /gene="obgE"
                     /locus_tag="VXC78_001051"
     CDS             15353..16663
                     /gene="obgE"
                     /locus_tag="VXC78_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV0583149.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGGDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            16673..16831
                     /locus_tag="VXC78_001052"
     CDS             16673..16831
                     /locus_tag="VXC78_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583150.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17918..19177
                     /locus_tag="VXC78_001053"
     CDS             17918..19177
                     /locus_tag="VXC78_001053"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0583151.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            19193..19744
                     /locus_tag="VXC78_001054"
     CDS             19193..19744
                     /locus_tag="VXC78_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0583152.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            19737..21014
                     /locus_tag="VXC78_001055"
     CDS             19737..21014
                     /locus_tag="VXC78_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0583153.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            21030..21890
                     /locus_tag="VXC78_001056"
     CDS             21030..21890
                     /locus_tag="VXC78_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV0583154.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            22271..23056
                     /locus_tag="VXC78_001057"
                     /pseudo
     CDS             22271..23056
                     /locus_tag="VXC78_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            23247..25538
                     /gene="pcrA"
                     /locus_tag="VXC78_001058"
     CDS             23247..25538
                     /gene="pcrA"
                     /locus_tag="VXC78_001058"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV0583155.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNNLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            25581..26261
                     /gene="radC"
                     /locus_tag="VXC78_001059"
     CDS             25581..26261
                     /gene="radC"
                     /locus_tag="VXC78_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV0583156.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQVSV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDYVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(26258..26947)
                     /locus_tag="VXC78_001060"
     CDS             complement(26258..26947)
                     /locus_tag="VXC78_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0583157.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYATKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(26965..27606)
                     /locus_tag="VXC78_001061"
     CDS             complement(26965..27606)
                     /locus_tag="VXC78_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV0583158.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(27689..27904)
                     /locus_tag="VXC78_001062"
     CDS             complement(27689..27904)
                     /locus_tag="VXC78_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0583159.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(27912..28259)
                     /locus_tag="VXC78_001063"
     CDS             complement(27912..28259)
                     /locus_tag="VXC78_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV0583160.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(28264..29379)
                     /locus_tag="VXC78_001064"
     CDS             complement(28264..29379)
                     /locus_tag="VXC78_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0583161.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPKNQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(29389..30348)
                     /locus_tag="VXC78_001065"
     CDS             complement(29389..30348)
                     /locus_tag="VXC78_001065"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0583162.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(30461..31030)
                     /locus_tag="VXC78_001066"
     CDS             complement(30461..31030)
                     /locus_tag="VXC78_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV0583163.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            31158..31829
                     /locus_tag="VXC78_001067"
     CDS             31158..31829
                     /locus_tag="VXC78_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV0583164.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            31813..32631
                     /locus_tag="VXC78_001068"
     CDS             31813..32631
                     /locus_tag="VXC78_001068"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV0583165.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            32628..33524
                     /locus_tag="VXC78_001069"
     CDS             32628..33524
                     /locus_tag="VXC78_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0583166.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            33568..34542
                     /gene="pta"
                     /locus_tag="VXC78_001070"
     CDS             33568..34542
                     /gene="pta"
                     /locus_tag="VXC78_001070"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV0583167.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(34803..36024)
                     /locus_tag="VXC78_001071"
                     /pseudo
     CDS             complement(34803..36024)
                     /locus_tag="VXC78_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        10872 a         6404 c         7899 g        10849 t
ORIGIN      
        1 tattttgttt atacaatttt ttctttaatt caattaggtg gtatgggaac tgatatgtta
       61 ttaaccaata taatatttcc caatataatg tcatttcttt tatttttacc tatagctatc
      121 tttatgcaaa tttgctgtat aagatttgat tccattttag caaaggcctt acctaatatt
      181 ttgctgatac ttattgtttt aatcacgttt cagagtgatt ggaatatatt tatacctgca
      241 acttattatt atacagaaat tcagtcaact acaaacttag gtattaaatt attagtttgt
      301 atctggatta tgggatttga atttttcctt cttccaaaac taataaaatt gaaagaacaa
      361 aatctagttt aaatgttgct cgaaaattaa ataattgaat acgattaaca atgaaacaat
      421 acaacgtgag tcatgacttc aaagtaattg attttatgat tctggtttct tacgcttaat
      481 taagcaagtt gtattcactt tatcaaattg ttattactct aaaaagcgtc taacagctat
      541 agagtgtctg tttgcttctc tttactttta ttttaaataa ttcattaacc ttccgtaagt
      601 gcccaataat aaggtgtgtt gaagaagtct gagataaaat agttctcagt cacaaaaaag
      661 ctatagattc ccattggtga acagctccct gtcaagtaga cagtaaaata atataaaatc
      721 ttaagcgacc tgattcctga attccagtgg agtcaggttg ttttttaacc gtctttctta
      781 atattgtctt acctataata gatatgctta tgagatatgt ttaataaatt aattttagtt
      841 caaaatgtcc agttaggaca ctttgaatga tttcttagtt ttatatatta tacttttctc
      901 aggagaaagc tagatgtaca gacgtttgag agatttgagg gaagatcacg atttgaccca
      961 aaaacaaata gctaaaatac tttcgtttac aaactcagct tatgctaaaa ttgaacgggg
     1021 tgagcatacg ttaacagcag atgtattggt aactctctca aacttttacg atgtcagtac
     1081 agactaccta ttggaattga cagattttcc tgataaaatt cgctttagaa aataatctcc
     1141 tcaatttcat agagtgtgaa aatgaggaga ttttttattt gttctttgaa aattaaatag
     1201 tccaaaatgg tactttcctc atttgtggag caaatttgaa tggctcgcca tgataagagc
     1261 gattttaaaa ccatcaataa aatagagcga tactttatat gccatgatac aaatgatata
     1321 caatgatact tctgaccgtt caggctgcca tcgtaaaaga gcagcaagtg aaattcttat
     1381 gatgacttca tcagtcatgc cacgttaaat gtgtgagttt gttagagaaa cgcaattaat
     1441 cctcaaaagg ttccccgaac cttttgagtt ccacagacgc atcacgtgga gtgtgtaagc
     1501 ttgttgctaa aagcgtaaaa accttggaac gaaaggaata atagacttcc tgcgaaacaa
     1561 aaatacaata caataaaact atggatgatg aagcaagtaa acaattaagc gatagccgtt
     1621 tcaagagcct tgtaggtgtt cagcgcacga gatgttagct gtgttaaaaa cagcttatca
     1681 acgcaacgta aacgcgcaaa aggtggacga aaaaccaaat taagcctaga cgatctcctc
     1741 atggtaacta ttcaatacat gcgagaatag cgcacttatg aacaaattgc ggctgatttt
     1801 ggcattcacg aaagcaactt aatccgtcgg agccaatggg ttgaagtaac tcttgttcaa
     1861 aatggtttta cgatttcaaa ttctgcccta attatgaaaa acagtaaaat tcgaaggatt
     1921 gtaaggtaag agtttttttc tttctgaaaa aatggtataa tagcaatcaa aactagaaaa
     1981 taaaacggaa tttggaacag atttgtctgt atcctagtag agtggtgatg ctatgaagat
     2041 tagtaagagg cacttattaa attattccat cttgattccc tacttgcttt tatctatttt
     2101 gggcttgatt gtggtctatt cgaccaccag tgctatttta attgaagaag gcaagagcgc
     2161 cttgcagttg gttcgaaacc aaggaatctt ttggattgtt agtttgatac tgattgcctt
     2221 aatttataaa ttgagactag attttttgag aaatgagcga ctaatcattt tagttatatt
     2281 aatagaaatg cttttattgt tcttggctcg ttttattggt atttccgtaa acggggcata
     2341 cggttggatt tcggttgcag gagtaactat tcagccagct gagtacttaa aaatcattat
     2401 tatttggtat ttagctcacc gattctccaa acagcaagaa gaaatagcta cttatgattt
     2461 tcaagttttg actcaaaatc aatggcttcc ccgtgctttt aatgattggc gattcgttct
     2521 cctagttctg attggaagtt tgggaatttt ccctgattta ggaaatgcga ctattttagt
     2581 cttggtttcc ttgattatgt atacagttag tggaatcgct tatcgctggt tttcaaccat
     2641 tctggcgctc gtatctgccg cttctgtctt tgtcttgacc actatcagcc taatcggtgt
     2701 tgagaccttt tcaaaaattc cagtatttgg ctatgtagcc aagcgcttta gtgccttttt
     2761 taatcctttt gccgatcgtg ctgatgcagg tcaccagtta gctaattctt attttgccat
     2821 ggtcaatggt ggttggtttg gtctaggtct tggaaactcg attgaaaaac gaggttattt
     2881 gccagaagct catacagact ttgtcttttc tatcgtgatt gaagaatttg gctttgctgg
     2941 tgccagtctt attttagctc tcttgttttt catgattttg cggattatct tggtcggtat
     3001 tcgagcggag aatcctttca atgccatggt tgcactcggt gtcggaggga tgatgttggt
     3061 tcaggtattt gtcaatatcg gagggatttc gggcttgatt ccatctacag gagtaacctt
     3121 ccccttctta tcccagggtg gaaatagtct tctagtctta tcagtggcag tagcctttgt
     3181 cttaaatatt gatgccagtg aaaaacgcgc taagttgtac cgagaattgg aaaatcaacc
     3241 aatgaacctt ctgttgaagt aggataaaga aaggatagtt tatgtctctt caaaaattag
     3301 aaaattatag taataaaagt gttgtgcaag aagaagtctt gattctaaca gaattactgg
     3361 aagatattac taaaaatatg cttgccccag agacctttga aaaaataata cagttgaaag
     3421 aattatcaac gcaggaagat tatcaaggtc taaaccgtct agtgactagc ttatcaaatg
     3481 atgaaatggt ctatatttca cgctatttct ctatcttacc tcttttgatc aatatttcag
     3541 aggatgtgga tttagcttat gaaatcaatc atcaaaataa tattgatcag gactatttag
     3601 gtaaattatc tacaacgatt aaattggtag cagaaaagga aaatgccgtt gagatcctag
     3661 aacacttgaa tgttgtccct gttttgacag cccatccaac acaagtgcaa cgcaaaagta
     3721 tgttggattt aacaaatcat attcatagtc ttttgcgtaa ataccgtgat gttaagttgg
     3781 ggttgatcaa taaagataaa tggtacaatg atttgcgtcg ttacatcgaa attatcatgc
     3841 agacagacat gattcgtgag aaaaaattaa aagtgactaa cgaaatcacg aatgctatgg
     3901 aatattataa cagctccttt ttgaaagctg tacctcattt gacgacggag tataagcgct
     3961 tagcgcaagc gcatggtctg aatttaaaac aggctaaacc aatcaccatg ggtatgtgga
     4021 taggtggtga ccgtgatgga aatccatttg ttacagcaga gaccttgaag cagtctgcac
     4081 tcactcaatg tgaagtcatc atgaactact atgataaaaa gatttaccaa ctttatcgtg
     4141 aattttctct ttcaactagc attgtcaacg tcagcaagca agtcagagaa atggctcgtc
     4201 aatccaagga taactcgatt taccgcgaaa aagagcttta ccgtcgtgcc ttgtttgata
     4261 ttcaatcaaa aattcaggca actaaaacct atctgattga ggatgaagaa gttgggactc
     4321 gttatgaaac cgccaatgat ttctacaagg atttgattgc cattcgagat tctctactag
     4381 aaaataaggg tgagtccttg atttcaggtg attttgtgga attattgcag gcagtagaga
     4441 tatttggttt ttacctagca tcaattgata tgcgacaaga ctctagcgtc tatgaagcct
     4501 gtgtggcaga actcttgaaa tcagcaggaa ttcattctcg ttatagcgag ttgagcgaag
     4561 aagaaaagtg tgaccttctc ttgaaagaat tagaagaaga tccccgaatt ctttctgcga
     4621 ctcacgcaga aaaatcagaa ttattagcaa aagaattagc tatttttaag acggctcgtg
     4681 ttttgaaaga taagttggga gatgatgtca tccgtcagac catcatttca catgcaacca
     4741 gcctttctga tatgctagaa ttagctattc tgttaaaaga agtaggactg gtggatacgg
     4801 aaagggcgcg tgttcagatt gttccccttt ttgaaacaat tgaagacttg gatcattcag
     4861 aagaaacaat gagaaaatat ctttctctta gccttgccaa aaaatggatt gactcacgaa
     4921 ataactacca agaaatcatg cttggctact ctgacagtaa taaagatggc ggttacttgt
     4981 catcatgttg gaccctctac aaggctcaac aacaattgac tgctattgga gatgaatttg
     5041 gcgttaaggt taccttcttc catggtcgtg gtggtactgt cggtcgtggt ggtgggccaa
     5101 cctatgaagc cattacatct caaccgctca agtctatcaa ggatcgtatc cgcttgacgg
     5161 agcagggtga agtaattggg aataaatacg gtaacaaaga cgccgcttac tataaccttg
     5221 aaatgctagt atcggcagct attaaccgta tgattactca gaagaagagc gataccaata
     5281 ccccaaatcg ttatgaagcc attatggatc aagtagtgga ccgtagttac gatatctacc
     5341 gtgatttggt ctttggtaat gagcatttct atgattattt cttcgagtca agtccaatca
     5401 aggctatttc aagttttaat attggttctc gtccagccgc tcgtaagact attactgaaa
     5461 tcggtggttt gcgtgccatc ccttgggtat tctcatggtc acagagtcgt gttatgttcc
     5521 ctggatggta cggggttggt tcaagcttca aggaatttat caataaaaat ccagagaata
     5581 ttgctatctt acgagatatg taccaaaatt ggcctttctt ccaatcgctt ctttcaaatg
     5641 ttgatatggt tttgtcaaaa tcaaatatga atattgcttt tgaatatgct aaactttgtg
     5701 aagacgagca agttaaggcc atctatgaga ctattttaaa tgaatggcaa gttactaaga
     5761 acgttatctt ggctattgaa ggacatgacg aactcttagc tgacaatcca tatctaaaag
     5821 ctagtctgga ttaccgtatg ccttacttta atattctcaa ctatattcag ttagagttga
     5881 ttaaacgcca acgtcgtgga gaattgtcca gtgatcaaga acgattgatt catatcacca
     5941 tcaacggaat tgcgacagga ttgcgtaatt caggttgata attttcaaga gtgaatgcta
     6001 aaagtgaata tcaaaaaaat tctaatagac tattgacaag tagtttaaaa atgatataat
     6061 ttaaccattc agaaaagtaa tcatacaaac tttttagaga gtctgtggta gctgaaaaca
     6121 gataagtggc gatgatgaaa attgggctga atgctattta gaatttgaaa ttataaaaat
     6181 tcggtaagca caccttacag tgcatctcgt tattgcgaga ctgagcgata gggaaattcc
     6241 ctataattga ggtggtaccg cgcatcgacg tcctcacaca agttttttgt gtgaggattt
     6301 ttttgatgga ggttagtatg gaaagaaaac gatggcgtcg cttgtttaga taagtgaaat
     6361 atgttaaagg aaataaaaag gagaaacaga atgaaaaata aacgtttaat tggaattatt
     6421 gctgcattag cagtcttagt agcaggaagc ttgatttatt cttcaatgaa taaatcagaa
     6481 gctcagaata ataaggatga gaagaaaata actaagattg gtgtgcttca atttgtgagc
     6541 catccatccc ttgatttgat ttataaaggg atccaagatg gacttgcaga agaaggatat
     6601 aaagatgatc aagttaaaat tgattttatg aactcagaag gtgaccaaag taaggttgcg
     6661 acaatgagta aacaattggt tgcaaatggg aatgaccttg tggttggtat cgcaacacca
     6721 gcagcccaag ggttggctag tgcaacaaaa gacctaccgg ttatcatggc cgctattaca
     6781 gacccaattg gtgctaactt ggttaaagat ttgaaaaaac caggtggcaa cattacaggg
     6841 gtatctgacc acaatccagc tcaacaacaa gttgaactca tcaaggctct gacaccgaat
     6901 gtgaaaacaa tcggagctct ttactcaagt agcgaagaca attcaaaaac acaggtcgaa
     6961 gaatttaagg cttatgctga aaaagcaggt ctgacagtgg aaacatttgc agttccttca
     7021 acaaatgaaa ttgcctcaac tgtcactgtt atgactagca aggtagatgc tatttgggtt
     7081 ccaattgata acaccattgc atcaggattt ccaacggttg tctctagcaa tcaaagttct
     7141 aagaaaccaa tttatcccag tgcgacagct atggtagaag taggtggttt ggcatcagtt
     7201 gtaattgacc aacatgacct tggtgtggca acaggtaaaa tgattgtgca agtcttgaaa
     7261 ggtgcaaaac cagccgatac cccagtcaat gtcttttcaa ctggtaagtc agtcatcaat
     7321 aaaaaaatag cacaagaact aggtattact attcctgagt ctgttctcaa agaagcagga
     7381 caagtcatcg aataaataag gtagggagga ggagactctt cccatttttt aaaaagatga
     7441 atatagaaag gattaaataa aatatgattg tttccattat ttctcaagga tttgtctggg
     7501 ctattctagg tctgggaatc tttatgacat ttaggatttt aaactttcca gatatgacga
     7561 cagaaggttc cttccctctt gggggagctg ttgctgtcac tttgataacc aaaggcgtga
     7621 acccattttt agcgacactt gttgctgtag gagcaggttg tttggctgga atggcagcag
     7681 gccttcttta tacaaaaggg aagatcccaa ccttgctctc agggattttg gtgatgactt
     7741 cttgtcactc aatcatgctc ttgattatgg gacgtgcgaa tttaggcctg cttggaacca
     7801 agcaaattca ggatgttttg ccttttgatt cggatttgaa tcaactcttg acaggtctca
     7861 tctttgtgag tattgttatt gctctcatgc tctttttctt ggacactaaa ctcggacaag
     7921 cctatattgc tacaggggat aatcctgata tggctagaag tttcgggatt catactggac
     7981 gcatggagct catgggcttg gtcttatcaa atggtgtgat tgcccttgca ggtgccctca
     8041 ttgctcagca agaaggttat gccgatgtgt ctcgagggat cggggttatc gttgtggggc
     8101 ttgcaagttt gattattgga gaagttattt tcaagagttt gagcttggca gagcgtttgg
     8161 ttactatcgt tgtaggttct atcgcttatc aatttttagt gtgggcagtt atcgcacttg
     8221 gctttaatac aagttacctt cgtttataca gtgccttgat tttagcagtc tgcctcatga
     8281 ttccaacatt taagcaaaca atcttgaaag gagccaagtt aagcaaatga cagcaattgt
     8341 agaattaaaa aatgcaacca aaatcgttaa aaatggcttt gatgaagaaa agattatttt
     8401 aaatgatgtt tccttagaaa tttttgaacg ggactttatc acgattttgg gcggaaatgg
     8461 tgctggaaaa tcaaccctct ttaacactat agcagggacc ttatcactaa ctagtggaac
     8521 tatccgtatt ttaggtgaag aactcactaa gttttcaccc gagaagcgtg ccaagtacct
     8581 gtctcgtgtc ttccaagatc caaagatggg gacagctccc cgtatgacgg tcgctgaaaa
     8641 tcttttaatc gccaagtttc gtggtgaaaa gcgtggattg ttaccacgac gcttgactag
     8701 ctataaggat gaatttcagg caaccattga aaaagtagga aatggtcttg agaaacactt
     8761 gaatacaccg attgagttct tatcaggtgg acaaagacag gctttgagtc tcttgatggc
     8821 aaccttgaag cgacctgaat tactcctgtt agatgagcat actgctgccc tggatccaaa
     8881 gactagtgtt gctttgatgg aattgacaga tgaatttgtt aagaaagatc agctaacagc
     8941 ccttatgatt actcatcata tggaagatgc tctcaaatac ggcaatcgct tgattgtcat
     9001 gaaagaagga cggattatcc aagatttaaa ccaagaagaa aaagcaaaaa tgaaaatctc
     9061 tgattattat caactctttg aataaagtag ggaaaatgag tgaaatggtt tacttttttt
     9121 ctgaaataaa gtatactata taaagtaaac tatgataaca tggaggtatt gtgtatggtt
     9181 gacaaacaag tcattgaaga aatcaaaaac aatgccaaca ttgtggaagt cataggagat
     9241 gtgatttctt tacaaaaggc aggacggaac tatctagggc tctgtccttt tcatggtgaa
     9301 aaaacacctt ctttcaacgt tgtagaggat aagcagtttt atcactgttt cggttgtggt
     9361 cgctcaggtg atgtctttaa gttcatcgag gagtaccaag gggttccctt tatagaggca
     9421 gtccaaatct taggtcagcg tgttggaatt gaggttgaaa aaccgcttta tagtgagcag
     9481 aagccagcct cacctcacca agctctttat gatatgcacg aagatgcagc caaattttac
     9541 catgcgattc tcatgacaac gactatgggc gaagaggcca gaaattacct ttatcagcgg
     9601 gggttgacag atgaagtgct taaacatttt tggattggtt tagcacctcc agaacgaaac
     9661 tatctctatc aacgtttgtc tgatcagtat cgtgaagagg atttactgga ttcaggcctg
     9721 ttttatctct cggatgccaa tcaatttgta gacacctttc acaatcgcat tatgtttccc
     9781 ctgacaaatg accaaggaaa ggtcattgcc ttctcaggtc gtatctggca aaaaacggat
     9841 tcacaaactt ctaagtataa aaacagccga tcgactgcaa tttttaacaa aagttacgaa
     9901 ttatatcata tggatagggc aaaaaaatct tctggaaaag ctagtgagat ttacttgatg
     9961 gaaggattca tggatgttat tgcagcctat cgggctggaa tcgaaagtgc tgtggcgtcg
    10021 atgggaacgg ccttgagtcg agagcatgtt gagcatctga aaaggttaac caagaaattg
    10081 gttcttgttt acgatggaga taaggctggg caagccgcga cattgaaagc attggatgaa
    10141 attggtgata tgcctgtgca aatcgtcagc atgcctgata acttggatcc tgatgagtat
    10201 ctacaaaaaa atggtccaga agacttggcc tatctattaa cgaaaactcg tattagtccg
    10261 attgagttct acattcatca gtacaaacct gaaaacagtg aaaatctgca ggctcagatt
    10321 gagtttcttg aaaaaatagc tcccttgatt gttcaagaaa agtccatcgc tgctcaaaac
    10381 agctatattc atattttagc tgacagtctg gcgtcctttg attataccca gattgagcag
    10441 attgttaatg agagtcgtca ggtgcaaagg cagaatcgca tggaaggaat ttccagaccg
    10501 acgccaatca ccatgccaat caccaagcag ttatcggcta ttatgagggc agaagcccat
    10561 ctactctatc ggatgatgga atcccctctt gttttgaacg attaccgttt gcgagaagac
    10621 tttgcatttg ctacacctga atttcaggtc ttatatgact tgcttggcca gtatggaaat
    10681 cttcctccag aagttttagc agagcagaca gaggaagttg aaagagcttg gtaccaagtt
    10741 ttagctcagg atttgcctgc tgaaatatcg ccgcaggaac ttagtgaagt agagatgact
    10801 cgaaacaagg ctctcttgaa tcaggacaat atgagaatca aaaagaaggt gcaggaagct
    10861 agccatgtag gagatacaga tacagcccta gaagaattgg aacgtttaat ttcccaaaag
    10921 agaagaatgg agtaataatg gcaacaaaac aaaaagaagt aacaacattt gacgtacagg
    10981 tagcagaatt tatccgtaat cataagcaaa aagggacagc aacagatgat gaaatcaatg
    11041 caagtctggt tattcctttt accttggacg ctgatgggat tgaagatctc ttgcaacgga
    11101 ttcaggatgc aggaatttct atcacagata acgaaggaaa tccaagtgcg cgtgttctta
    11161 gcaatgaaga agaaccagaa ctcagcgatg aggacttgat tgggtcaact tctgctaagg
    11221 tcaatgaccc tgtccgtatg tacttgaaag aaataggggt cgttcctctc ttgaccaatg
    11281 aagaggagaa agagttggca ctggctgttg aagctggtga tatcgaagcc aaacaacgtc
    11341 ttgcggaagc caatcttcgt ttggttgttt ccattgccaa acgctatgtc ggtcgtggta
    11401 tgcagttcct tgacttgatt caagaaggaa atatgggctt gatgaaggcg gttgacaagt
    11461 ttgactattc taaagggttc aagttttcaa cttatgcaac ttggtggatt cgtcaggcta
    11521 tcactcgtgc tattgcggac caagctcgta ccatccgtat cccagttcac atggttgaaa
    11581 ctatcaataa attggttcgt gaacagcgga atctccttca agaattgggg caagatccga
    11641 caccagaaca gattgctgaa cgaatggata tgacacctga taaggttcgt gaaatcttga
    11701 agattgccca agaaccagta tctcttgaaa ctcctatcgg tgaagaggac gatagccacc
    11761 ttggagactt tatcgaagat gaagtgattg aaaatccagt ggattatacg actcgtatcg
    11821 tcttgcgtga gcaattggat gaaatcttag atactcttac agaccgtgaa gaaaatgttc
    11881 tgcgtctacg ttttggacta gatgatggaa aaatgcgcac acttgaagat gtggggaaag
    11941 tctttaacgt aactcgtgag cgtatccgtc agattgaagc aaaggctttg agaaaactac
    12001 gccaaccaag tcgtagcaaa ccgcttcgtg attttattga agactaagag tgaggaaaat
    12061 atggcttata cagaagagca aattgaaaac atcaaaacac ggattttaac agccttggaa
    12121 gaagtcatcg accctgagtt gggaatcgat attgtcaatc ttggtttgat ctatgagatt
    12181 cgttttgacg gtgacacagg gcaaacagag attgacatga ctttgacaac tatgggttgt
    12241 cccttagcag accttttgac agaccagatt tatgatgcta tgatagaggt tccagaagta
    12301 acggatactg aggttaaatt agtctggtat ccagcctgga cagttgaaaa aatgagtcgc
    12361 tatgcccgca ttgccctagg cattaagtaa acatataaaa gcatgtgaga gactgttgga
    12421 aaagtgagga aatttcccct cttttcctct agtctctcct ttcttttgct gattttattc
    12481 aaagaaaatg atataatagt agttatggag aaaaagaaat tacgcatcaa tatgttgagt
    12541 tcaagtgaga aagtagcagg acagggagtt tcaggtgctt accgtgaatt agttcgtctt
    12601 cttcaccgtg ctgccaagga ccaattgatt gttacagaaa atcttccaat cgaggcagat
    12661 gtgactcact ttcatacgat tgattttccc tattatttat caaccttcca aaagaaacgc
    12721 tcagggagaa agattggcta tgtgcatttc ttgccagcta cacttgaggg aagtttgaaa
    12781 attccatttt tcttaaaggg aattgtgaaa cgctatgtat tttcttttta caaccggatg
    12841 gagcacttgg ttgtggtcaa tcctatgttt attgaggatt tggtagcagc tggtattcca
    12901 cgtgaaaaag tgacctatat tcctaacttt gtcaacaagg aaaaatggca tcctctacca
    12961 caagaagagg tagttagact gcgcacagat cttggtctta gtgacaatca gtttatcgta
    13021 gtaggtgctg ggcaagttca gaaacgtaaa gggattgatg actttatccg tctggctgag
    13081 gaattgcctc agattacctt tatctgggct ggtggcttct cttttggtgg tatgacagat
    13141 ggttatgaac actataagaa aattatggaa aatcccccta aaaatttgat ttttccaggc
    13201 attgtatcgc cagagcggat gcgcgaattg tatgctctag cggatctttt cttgttgcct
    13261 agttacaatg agctctttcc tatgactatt ttagaagctg cgagttgtga ggctcctatt
    13321 atgttgcgtg atttagatct ctataaggtg attttggagg gaaattatcg ggcgacagcg
    13381 ggtagagaag agatgaaaga ggctattttg gaatatcaag caaatcctgc tgtcttaaaa
    13441 gatctcaaag aaaaggctaa gaatatttcc agagagtatt ctgaagagca tctgttacaa
    13501 atctggttgg acttttatga gaaacaagcc gctttaggga gaaagtaaaa agtgaggtaa
    13561 tctatgcgaa ttggtttatt tacagatacc tattttcctc aggtttctgg tgttgcgacc
    13621 agtattcgaa ccttgaaaac agaacttgaa aagcagggac atgctgtttt tatctttacg
    13681 acgacagata aggatgtcaa tcgctacgaa gattggcaaa ttatccgcat tccaagtgtt
    13741 cctttctttg cttttaagga tcgtcgcttt gcctaccgag gttttagcaa ggcacttgaa
    13801 attgctaaac agtatcagct agatattatc catactcaga cagaattttc tcttggcctg
    13861 ttggggattt ggattgcgcg tgaattgaaa attccagtca tccataccta tcacacccag
    13921 tatgaagact atgtccatta tattgctaag gggatgttga tccggccgag tatggtcaag
    13981 tatctggtta gaggtttcct gcatgatgtg gatggggtta tttgccctag tgagattgtc
    14041 cgtgacttgc tatctgatta taaggtcaag gttgaaaaac gggtcattcc tactgggatt
    14101 gaattagcca agtttgagcg tccggaaatc aagcaggaaa atttgaaaga actgcgtagt
    14161 aaactaggga ttcaagatgg tgaaaagacg ttgcttagtc tttcgagaat ctcctatgaa
    14221 aaaaatattc aagcagtttt agcagccttt gctgatgttc tgaaagagga agacaaggtt
    14281 aaactggtag tagctgggga tggcccttat ctgaatgacc tcaaagagca agctcagaac
    14341 ctagagattc aagactcagt catctttaca gggatgattg ctcctagtga gacggctctt
    14401 tactataaag cggcggattt cttcatttcg gcatcgacaa gcgaaacgca aggtttgacc
    14461 tacttggaaa gcttagccag tggaacacct gtcattgctc acggaaatcc ttatttgaac
    14521 aacctcatca gtgataaaat gtttggaacc ttgtactatg gagaacatga tttggctggt
    14581 gctattttgg aagccctgat tgcaacacca gacatgaacg agcatacctt atcagagaaa
    14641 ttgtatgaga tttcagctga gaactttggg aaacgagtgc atgagtttta tctggatgcc
    14701 attatttcaa ataacttcca gaaagatttg gctaaagatg atacggtcag tcagcgtatc
    14761 tttaagacag ttttgtatct tcagcaacag gtggttgctg tacctgtaaa aggatctaga
    14821 cgcatgttga aggcttcaaa aacacagttg atcagtatga gagactattg gaaagaccat
    14881 gaagaataga aagaggaaca gctatgaaaa aaacaattaa tgagaagcgg tcgtgataaa
    14941 aagattgcgg gtgtttgtgc tggggtggcc cattatctgg atatggatcc gactatcgtt
    15001 caagtcattt ggggtgttct tacttgctgt tacggagctg gaattgtagc ttacattatt
    15061 ttatggatta tcgcaccagt agcaacagac tattgaaaac tagctcaatt catgctaaga
    15121 taatagaaaa tagaatgtaa cgaaggagag aaaaatggca tttggagata atggaaatcg
    15181 taaaaaaact atgtttgaga aaataacctt gtttatcgtg attatcatgc tagtagcaag
    15241 tttattggga atttttgcaa ctgcaattgg tgccctcagt aatctataaa atagattcaa
    15301 gaaaatttag tgactgggat ttcccagccc ttttttaaag tgagaagaaa taatgagtat
    15361 gtttttagat acagctaaga ttaaggtcaa ggctggtaat ggtggcgatg gtatggttgc
    15421 ctttcgtcgt gaaaaatatg tccctaatgg aggcccttgg ggtggtgatg gtggtcgtgg
    15481 aggcaatgtg gtcttcgttg tagacgaagg actacgtacc ttgatggatt tccgctacaa
    15541 tcgtcatttc aaggctgatt ctggtgaaaa agggatgacc aaagggatgc atggtcgtgg
    15601 tgctgaggac cttagagttc gagtaccaca aggtacgact gttcgtgatg cggagactgg
    15661 caaggtttta acagatttga ttgaacatgg gcaagaattt atcgttgccc acggtggtcg
    15721 tggtggacgt ggaaatattc gtttcgcgac accaaaaaat cctgcaccgg aaatctctga
    15781 aaatggagaa ccaggtcagg aacgtgagtt acaattggaa ctaaaaatct tggcagatgt
    15841 cggtttagta ggattcccat ctgtagggaa gtcaacactt ttaagtgtta ttacctcagc
    15901 taagcctaaa attggtgcct accactttac cactattgta ccaaatttag gtatggttcg
    15961 cacccaatca ggtgaatcct ttgcagtagc cgacttgcca ggtttgattg aaggggctag
    16021 tcaaggtgtt ggtttgggaa ctcagttcct ccgtcacatc gagcgtacac gtgttatcct
    16081 tcacatcatt gatatgtcag ctagcgaagg ccgtgatcca tatgaggact acctagctat
    16141 caataaagag ctggagtctt acaatcttcg cctcatggag cgtccacaga ttattgtagc
    16201 taataagatg gacatgcctg agagtcagga aaatcttgaa gaatttaaga aaaaattgtc
    16261 tgaaaattat gatgaatttg aagagttacc agctatcttc ccaatttctg gattgaccaa
    16321 gcaaggtctg gcaacacttt tagatgctac agctgaattg ttagacaaga caccagaatt
    16381 tttgctctac gacgagtccg atatggaaga agaagcttac tatggatttg acgaagaaga
    16441 aaaagccttt gaaattagtc gtgatgacga tgcgacatgg gtactttctg gtgaaaaact
    16501 catgaaactc tttaatatga ccaactttga tcgtgatgaa tctgtcatga aatttgcccg
    16561 tcagcttcgt ggtatggggg gtgatgaagc ccttcgtgcg cgtggagcta aagatgggga
    16621 tttggtccgc attggtaaat ttgagtttga atttgtagac taggagactg gtatgggaga
    16681 taaaccgata tctttccgag atgcggatgg taattttgtt tccgccgcag acgtttggaa
    16741 tgaaaagaaa ttggaagaac tatttaatcg tctcaatcca aatcgtgcct tgagattggc
    16801 acgaactaaa aaggaaaatc catctcagta aagaagctaa aaaatcccgt gcctcatcag
    16861 acacgggatt ttgtggtacg acaggcatgt atagcaaact gaatctggaa tagcacagca
    16921 tatcttctaa aatattgcta taaattgatt tgaatttcaa aattaaattg ttttattctt
    16981 atttcaattt gttatagtat atctgatgtc aaagttctcg gcgagtcaaa tagtgattcc
    17041 caagcctgac tatcgtgagg tagcggatta aaatggtctg gggatagacc gttttaagtc
    17101 tgatgctgga aataagaatt gtcagaagaa gggatagcga aatcgtggct ctacgaacag
    17161 gaacgtgata ataaggcgta tatagcgaat aagagggcct caaactctaa agtccaaaaa
    17221 ggtagtcgta acctatatgc gtaaatcatg agagtaattg aattcgtact aagattttct
    17281 atttttactg taacctttta acgtcctcat atcttgtata cacgaggaaa gatgtacgac
    17341 ttatcccgtg aggtctatca ctataaagag aaaacgacag atagaagtga tcctgagtca
    17401 cggttatctt taaaatagat tgtctgatag gatgctagcc tgaaaacgtc ttgttcatga
    17461 aatataggac ggtatgtata aaacgcttct gtgaactgag agaaggggga gaagttcttg
    17521 ctaaaattta gttgaacagc cgtattccga tacttagata agagatctag tcttagctcc
    17581 tactcagttt caggggataa aaaaggggca atagcgattc gagaaagatt atactcttcg
    17641 aaaatctctt caaatcacgt caatatcgcc ttgccgtatg tgtaggatac taactacgtc
    17701 agttccatct acaatctcaa aacagtgttt tgagcaacct gcggctagtt tcctagtttg
    17761 atctttgatt tttattgagt attagtaatt cagttactaa ctcgtcaact ctgatttatc
    17821 caataaaatt gaaaaggatg gaaaaaagga taaatttatg atatacttta ttttgaagac
    17881 cttattagaa atcttgaaag agtattgaaa acttagaatg agaaaaattg ttatcaatgg
    17941 tggattacca ctgcaaggtg aaattactat tagtggtgct aaaaatagtg ttgtggcctt
    18001 aattccagct attatattgg ctgatgatgt ggtgactttg gattgtgttc cagatatttc
    18061 ggatgtagcc agtcttgtcg aaatcatgga attaatggga gctactgtta agcgttatga
    18121 cgatgtcttg gagattgatc caagaggtgt tcaaaatatt ccaatgcctt atggtaaaat
    18181 taacagtctt cgtgcatctt actattttta tgggagcctc ttaggccgtt ttggtgaagc
    18241 gacagttggt ctaccgggag gatgtgatct tggtcctcgt ccgattgact tacaccttaa
    18301 ggcgtttgaa gctatgggtg ccactgctag ctacgaggga gataacatga agttatctgc
    18361 taaagataca ggacttcatg gtgcaagtat ttacatggat acggttagtg tgggagcaac
    18421 gattaatacg atgattgctg cggttaaagc aaatggtcgt actattattg aaaatgcagc
    18481 ccgtgaacct gagattattg atgtagctac tctcttgaat aatatgggtg cccatatccg
    18541 tggggcagga actaatatca tcattattga tggtgttgaa agattacatg ggacacgtca
    18601 tcaggtgatt ccagaccgca ttgaagctgg aacatatata tctttagctg ctgcagttgg
    18661 taaaggaatt cgtataaata atgttcttta cgaacacctg gaagggttta ttgctaagtt
    18721 ggaagaaatg ggagtgagaa tgactgtatc tgaagacagc atttttgtcg aggaacagtc
    18781 taatttgaaa gcaatcaata ttaagacagc tccttaccca ggctttgcaa ctgatttgca
    18841 acaaccgctt acccctcttt tactaagagc gaatggtcgt ggtacaattg tcgatacgat
    18901 ttacgaaaaa cgtgtaaatc atgtttttga actagcaaag atggatgcgg atatttcgac
    18961 aacaaatggt catattttgt acacgggtgg acgtgattta cgtggggcca gtgttaaagc
    19021 gaccgactta agagctgggg ctgcactagt cattgctggg cttatggctg aaggtaaaac
    19081 tgaaattacc aatatcgagt ttatcttacg tggttattct gatattatcg aaaaattacg
    19141 taatttagga gcggatatta gacttgttga ggattaaacc gtagaggtgt ttatgaatat
    19201 ttggaccaaa ttagcaatgt tttctttttt tgaaacggat cgcttgtatt tgcgtccttt
    19261 cttttttagt gatagtcagg acttccgcga gatagcttca aatccagaaa atcttcaatt
    19321 tattttccca acgcaggcaa gtctggaaga aagtcaatat gcactggcca attactttat
    19381 gaagtcccct ttgggagtgt gggcaatttg tgaccagaaa aatcaacaaa tgattggttc
    19441 tattaaattt gagaagttag atgaaatcaa aaaagaagct gagcttggct attttttgag
    19501 aaaagatgct tggtcgcaag gatttatgac agaggttgtt agaaaaattt gtcagctttc
    19561 ttttgaggaa tttggcttaa aacaattatt tatcattacc caccttgaaa atgaagctag
    19621 ccaaagagtt gctcttaagt ctggatttag tttgttccgt cagtttaagg gaagtgatcg
    19681 ttacacaaga aaaatgcggg attatcttga atttcggtat gtaaaaggag agttcaatga
    19741 gtaagcatca ggaaattcta agctatttgg aggaattacc agtaggtaaa agggtcagtg
    19801 ttcgtagcat ttcgaatcat ctaggagtta gtgatggaac agcctatcga gctattaaag
    19861 aagctgaaaa ccgtggaatt gtggagaccc gtcctagaag tggaacaatt cgtgttaaat
    19921 cccagaaagt tgctatagag agattaacgt ttgctgaaat tgcagaagtg acttcttctg
    19981 aggttctggc tgggcaagaa ggtttagaga gagagtttag taagttttca attggtgcca
    20041 tgactgaaca aaatatcttg tcttaccttc atgatggggg gctcttgatt gtcggagacc
    20101 gaacccgtat tcagttgcta gccttggaaa atgaaaatgc agttctggtt acagggggat
    20161 ttcaggttca tgatgatgtg cttaaactgg ccaatcaaaa agggattcct gttctaagaa
    20221 gtaagcatga tacctttacc gtcgcgacca tgatcaataa agccttgtca aatgtccaaa
    20281 tcaagactga tattctgaca gttgagaaac tttatcgccc tagtcatgag tatggttttc
    20341 tgagagagac agatacagtt aaagattatt tggacttggt tcgtaagaat cgtagcagcc
    20401 gtttccctgt tatcaatcaa catcaggtcg ttgttggcgt tgtaaccatg agagacgctg
    20461 gtgataaatc accaagcacg acaattgata aggttatgtc tcgtagtcta tttttggttg
    20521 ggttatcgac aaatattgcc aatgtgagtc aacggatgat cgcagaagac tttgaaatgg
    20581 taccagttgt tcgaagcaat caaactttgc ttggcgttgt gacgcgacga gatgtcatgg
    20641 agaagatgag ccgttcccaa gtttcggctc taccaacttt ttctgagcag attggacaaa
    20701 agctctctta tcaccatgat gaagtagtca ttacagtgga accctttatg ctagaaaaaa
    20761 atggagtttt ggctaatggt gtattggcag aaattctgac ccacatgacc caagatttag
    20821 ttgttaatag tggtcgcaat ctcattatcg agcagatgct gatctacttt ttgcaggctg
    20881 ttcagataga tgatatattg cgcattcagg cacggattat tcatcatacg agacggtcag
    20941 ctataattga ttacgatatt tatcatggtc accagattgt ttcaaaagca aatgtgactg
    21001 ttaaaattaa ttagaaacta ggagaaaaga tgataacatt aaaatcagct cgtgaaatcg
    21061 aagctatgga caaggctggt gattttctag caagtattca tataggctta cgtgatttga
    21121 ttaagccagg cgtagatatg tgggaagttg aagaatatgt ccgccgtcgt tgtaaagaag
    21181 aaaatttcct tccacttcag attggggttg acggtgccat gatggactat ccttatgcta
    21241 cctgttgctc tcttaacgat gaagtggctc acgctttccc tcgtcattat atcttgaaag
    21301 atggtgattt gctcaaagtt gatatggttt tgggaggtcc cattgctaaa tctgacctga
    21361 atgtctcaaa attaaacttc aacaatgttg aacaaatgaa aaaatacact cagagctatt
    21421 ctggtggttt agcagactca tgttgggctt atgctgttgg tacaccgtcc gaagaagtca
    21481 aaaacttgat ggatgtaacc aaagaagcta tgtacaaggg tattgagcaa gctgttgttg
    21541 gaaatcgtat cggtgatatc ggtgcggcta ttcaagaata cgctgaaagt cgtggttacg
    21601 gtgtagtgcg tgatttggtt ggtcatggtg ttggcccaac tatgcacgaa gaaccaatgg
    21661 ttcctaacta tggtattgca ggtcgtggac tccgtcttcg tgaaggaatg gtcttaacca
    21721 ttgaaccaat gatcaataca ggcgattggg aaattgatac agatatgaaa actggttggg
    21781 cgcataagac cattgacggt ggattgtcat gtcagtatga acaccaattt gtcattacga
    21841 aagatggacc tgttatcttg actagccaag gtgaagaagg aacttattaa taaaaagtga
    21901 aaagactact ggaagtttat tttgataaaa aatccagtag atcttttcat aataaaacgc
    21961 attgtatcaa gtgttaggag ctgatatcat gcgtttttct gcttttaaga ttttttccaa
    22021 ctctgtttgt aagcgcatca taacaaaggg tctaggattc agggctctcc tcctatatac
    22081 tattagtaaa gtaaaactaa gggaggatat tttagtgtcg cagtctattg ttcctgtaga
    22141 gattccacaa tattgtcgtt ttgattctaa aaagagaaat ggaattctgt ttaacgttcg
    22201 tattgccaat cttaaattta ccttttttag attagactcc ctgcgaaaca aaatatggta
    22261 tagtagttct atgaatgatg aagcaagtaa acaactaact gatgcacgat ttaagcgtct
    22321 tgttggtgtt cagcgcacga cttttgaaga gatattagct gtattaaaaa cagcttatca
    22381 acttaaacac gcaaaaggtg gacgaaaacc taaattaagc ctagaagacc ttcttatggc
    22441 cactcttcac tatgtgcgag aatatcgaac ttatgaagaa attgcggctg attttggtat
    22501 ccacgaaagc aacttactcc gtcggagcca atgggttgaa gtaactcttg ttcaaaggtg
    22561 gtgttacgat ttcaagaact cctctcagct ctgaggacac ggtaatgatt gatgcgacgg
    22621 aagtaaaaat caatcgccct aaaaaagaat tagcgaatca ttctggtaaa aagaaatttc
    22681 acgctatgaa ggctcaagcg attgtcacaa gtcaagggag aattgtttct attgtcatga
    22741 tatgaagttg ttcaaaatga gtcgcagaaa tattggacaa gctggtaaaa tcttggctga
    22801 cagtggttat caagggctca tgaagatata tcctcaagca caaactccac gtaaatccag
    22861 caaactcaag ccactaatag ctgaagataa agcttataac catgcgctat ctaaggagag
    22921 aagcaaggtt gagaacatct ttgccaaagt aaaaacgttt aaaatgtttt caacaaccta
    22981 tcgaagtcat cgtaaacgct tcggattacg aatgaatttg agtgctggta ttatcaatca
    23041 tgaactagga ttctagtttt gcaggaagtc tattgaggta ttgagctagt ttatgaaaaa
    23101 attgggtgaa aagtcgagtg ttttagaaac ccacagtgta gtattctagt ttcaatccac
    23161 tatattttgc tactccccgt aaagtttcta ttttccctga tttctgatat aatagaaata
    23221 ttgacttcaa gagtaaggaa gagaagatga acgcattatt aaatggaatg aatgaccgtc
    23281 aggctgaggc ggtgcaaacg acagaaggtc ccttgctaat catggcaggg gctggttctg
    23341 gaaagactcg tgttttaacc caccgtatcg cttatttgat tgatgaaaag ctggtcaatc
    23401 cttggaatat cttggccatt acctttacca acaaggctgc gcgtgagatg aaagagcgtg
    23461 cttatagcct caatccagct actcaggact gtctgattgc gaccttccac tccatgtgtg
    23521 tgcgtatttt gcgtcgcgat gcggaccata ttggctacaa tcgtaatttt acaattgtgg
    23581 atcctggtga acagcgaacg ctcatgaaac gtattctcaa acagttgaac ttggatccta
    23641 aaaaatggaa tgaacgaact attttgggga ccatttccaa tgctaagaat aatttgattg
    23701 atgatgttgc ttatgctgcc caagctggcg atatgtatac gcaaattgtg gcccagtgtt
    23761 atacagccta tcaaaaagaa cttcgtcagt ccgaatccgt tgactttgat gatttgatta
    23821 tgctgacctt gcgtctcttt gatcaaaatc ctgatgtttt gacctactac cagcaaaaat
    23881 tccaatacat ccacgttgat gagtaccaag ataccaacca cgctcagtac caattggtca
    23941 aactcttggc ttcccgtttt aaaaatatct gtgtggttgg ggatgcggac cagtctatct
    24001 acggttggcg tggtgctgat atgcagaata tcttggactt tgaaaaggat taccccaaag
    24061 ccaaggttgt tttgttggag gaaaattacc gctcaaccaa aaccattctc caagcggcca
    24121 acgaggttat taaaaataat aaaaatcgcc gtcctaaaaa tctctggact caaaacgctg
    24181 atggggagca aatcgtttac tatcgtgctg atgatgagct ggatgaggct gtatttgtag
    24241 ccagaaccat cgatgaactt agtcgcagtc aaaacttcct tcataaggat tttgcagttc
    24301 tctatcggac taatgcccag tcccgtacaa ttgaggaagc cctgctcaag tctaacattc
    24361 cttataccat ggttggcgga accaaattct acagccgtaa ggaaattcgc gatattattg
    24421 cttatctcaa ccttattgct aatttgagtg acaatattag ttttgagcgt attatcaacg
    24481 agcctaaacg tggaattggt ctaggtacag ttgagaaaat ccgtgatttt gcaaatttgc
    24541 aaaatatgtc tatgctggat gcttctgcta atattatgtt gtctggtatc aagggtaagg
    24601 cagcccaatc tatctgggat tttgccaata tgatgcttga tttgcgggag cagctagacc
    24661 acttaagcat tacagagttg gttgagtccg tcctagaaaa aacaggttat gtcgatattc
    24721 ttaacgccca agcgactcta gaaagcaagg cacgggttga aaatatcgaa gagtttcttt
    24781 ctgttacgaa gaactttgat gacaccacgg atgtgacaga agaggaaact ggtctggaca
    24841 aactgagtcg tttcttaaat gacttggctt tgattgccga cacagattca ggtagtcagg
    24901 agacatcaga agtgaccttg atgaccctgc atgctgccaa aggtctcgaa tttccagttg
    24961 tctttttgat tgggatggaa gaaaatgtct ttccacttag tcgtgcgact gaagatccag
    25021 atgaattaga agaagagcgc cgtctagcct atgtaggtat cacgcgtgca gagaaaattc
    25081 tctatctgac caatgccaac tcacgcttgc tttttggtcg taccaattat aaccgtccga
    25141 ctcgttttat taacgaaatc agttcagact tgcttgagta tcaaggtctg gctcgtcctg
    25201 caaatacaag ctttaaggca tcatatagca gtggtagtat ttcctttggt caaggtatga
    25261 gtttggctca ggctcttcaa gaccgtaaac gcggtgctgc cccaaaatca atccagtcaa
    25321 gcggtcttcc atttggtcaa tttacagctg gcgcaaaacc agcatctagc gaggcaaatt
    25381 ggtccattgg tgatattgct ctccacaaga aatggggaga gggaaccgtt ctggaagttt
    25441 caggtagcgg tgctaggcag gaattgaaaa tcaatttccc agaagtaggt ttgaaaaaac
    25501 ttttagccag tgtggctcca attgagaaaa aaatctaatt ttccatcctt ctcacgaata
    25561 ataaagtgag gaggattttt atgtacagta tttcattcca agaagattca ctattaccaa
    25621 gagaaaggct ggccaaggaa ggagttgaag cgcttagtaa ccaagagttg ctagctattt
    25681 tactcaggac aggaacacgt caagttagcg tttttgaaat tgcccaaaaa gtcttgaaca
    25741 atctttcaag cctaacggat ttgaaaaaaa tgaccctgca ggaattgcag agtttgtctg
    25801 gtattgggcg tgttaaggcc atagaattac aagctatgat tgaactgggg catcgtattc
    25861 acaaacacga gactcttgaa atggaaagta ttctcagcag tcaaaagttg gccaagaaga
    25921 tgcagcagga attaggggat aaaaaacaag agcacctggt ggcactctat ctcaatactc
    25981 aaaatcaaat catccatcag cagaccattt ttatcggttc tgtaactcgt agtatcgctg
    26041 aaccgcgaga gattcttcac tatgcaatca agcatatggc gacttctctt atcttggtcc
    26101 acaatcatcc ttcaggagcg gtagcgccta gccaaaatga tgattatgtc actaaacttg
    26161 ttaaagaagc ctgcgaactg atgggaattg ttctcttgga ccatttgatt gtctctcatt
    26221 ctaattactt tagttatcgt gaaaagacag atttaatcta aagttcatta acgacatagt
    26281 caaagagttt cttatctttg ggacgatttt caaaaagaag ttctggatgc cattggacac
    26341 cgagaaaggc gacatcatcc gtactcatga cagcctcaat gataccatct ttaggatcat
    26401 gagccacaac ttttaaattt ggtgctaagt ccttgatgct ctggtggtgg aaggagttga
    26461 tatgagagat ttctccatag atttcttgga gaacggtatc tggttctgtc accaagcgtt
    26521 gagttgtgta ctcaacagaa gaatcctgcc aatggtcttc gatatcttgg tacaaagttc
    26581 cacccatggc aacgttaaag agttgggtac cacggcagac agagaaaatg ggcttttttt
    26641 gtttaatagc ttccttgatg agggccagtt cgaagatatc tctttgaagg tgatagtcat
    26701 cgctatcaat ggttttgggt tcgccataaa attttggatc gacattttgc ccacctgtta
    26761 agatgagctt gtcaatcaaa ctgatatagt ggcaggccat ttcttgatca ccaatcggta
    26821 ggatgatggg aatccctcca gcatctttaa cgccttcaac aaagcctttt gttgcgtagc
    26881 tcatcatgat gtcatcatct ggatgagttt tttcgtttcc tgtaatccca ataactggtt
    26941 ttttcataaa atgattttcg ctttctaatc ctcttttcgc atgaagtaga ggagggtttg
    27001 gagttcactt gtcaaatcga catactgaac gaccacgtct tttggtaaat gcagatggac
    27061 tggtgaaaaa ctgagaattc ctttcacacc agcatcaacc aagagattag caacctcttg
    27121 tgacttgacg ctgggaacag ttaggatagc agtcttcaca tcagcatcct tgattttatc
    27181 cttgatctga gaaatcccgt aaatgggaat cccgtcagga gtttgggtac cgacttcagg
    27241 atggtcgtct aggtcaaagg ccatgataat cttcatcttg ttacgttcgt ggaagcggta
    27301 gtggagaagg gcatggccca tatttccaat accaaccagc atgacattgg taatagagtt
    27361 gtcattgagc aaatcggcaa aaaatgtcat tagttttttg acatcatagc caaaaccacg
    27421 acgaccaagt tcaccaaaat aggaaaaatc acgacgtacg gtcgctgaat caataccgat
    27481 agcctctgca atttgcttag agttggcacg ttcaatcttt tctgcatgaa atctcttaaa
    27541 aattcgatag tagagagaga gtctttttgc tgtagctttt ggaatagcaa actgtttatc
    27601 tttcacaaaa tcacaacctt tctattcttc tattttatag aaacattgtg aaaaaatcaa
    27661 caaaaataag aaaaaactaa gaaaaatctt agttttgatg taaaaaatct gcatgagata
    27721 gaaaacggta gaggtctccg accagcccct gataaacttt tttgccccta aaagtcagag
    27781 aagtcacata aagtgtatct ggtaaggtta cacatcctga caaagtcaac atgagagcct
    27841 catgatcctc atacttgaga gtacgctcta catgatagca gtccttatag gtcagttcaa
    27901 acattttggc tctatctttc cgattttgta aagacaccac gttctaccaa gctatccatg
    27961 aggaagtaga atttttcctg atgaatatgg tggtcttctg atttgaaaat atcaactaga
    28021 cgaaggccaa acttgtcagt gatattgatt ttagcccctg taagttcctt gttaatgatg
    28081 attttgagtt ggaagccttc accgctgttt ggcacttttt ccaaaaggcg agtcagttca
    28141 tagttaccaa ccttagtttc aaaaaaggtg ttatctttga gggtgaattt tttaacagaa
    28201 gggctaagag tgtaatcgta acgacaattt tttaactgaa tgattttttc aaatgccata
    28261 tggctaacct ccgataattt cttttaaggt ttttgcgagg gtttgtaggt cttcaacggt
    28321 attttgtggc gacaaactga tgcgaaggga ttccttcaag cgttctgaat ttgcgccata
    28381 catggcttca agaacatggc tggattggac aacgcctgca gtacaggctg agccagtaga
    28441 gattgaaatt ccagctaaat ctagccgaag gagtaagagg tcatttttct gaccaggaaa
    28501 tccaatattg agaacataag ggagatgatg ttttcctcta ttcaagtaat actgaatgcc
    28561 ctccagctct gccagaaagg cagtttctag attttgtaca tgttgaaaat gttcttcttg
    28621 tttttctagg tcttctttta gggctgcaac catgcctacg atggcaggca gattttcagt
    28681 tcctgcacgt tttttctgtt cctggtctcc gccatgtaga taggaatcaa agtccatgct
    28741 agatgcgtag agaaaaccga ttcccttagg accatggaat ttgtgggcag aagcagtgag
    28801 aaaatcaatg cccaattctt ctgaatgaat tgggatttta ccaatagcct gaactgcatc
    28861 aacatgatag gcagcagggt gttgcttgag tatttggcca atttcagcga tgggcagtag
    28921 gtttcctgtc tcattattgg caaacatggt agaaaccaaa atcgtatcgt cacgtaaagc
    28981 cttttgaatt tgctgggctg tgatttcttg attttttggc tggataatgg ttgcttcaaa
    29041 cccaaagtgt tgaaccaagt aatcaattgt ttcaaggaca gcatggtgct cgatggcagt
    29101 tgtgatgata tgttttcctt gttcttggtg acgaagacag tagccaatga tggtagtatt
    29161 attgccttca gtcccaccag aagtgaaaaa gatatgttga ggttttgtcc ttagtaactg
    29221 ggctagttcc tgacgggctt ctcgcaagag tttgccagct tgacgaccat gaccatgaat
    29281 actagaagga tttccgtggg tttcttgcat aaccttggtc atagctgaaa tagcaactgc
    29341 tgacatagga gtcgttgcag cattgtccaa ataaatcaaa gaatcacctt atttcttttt
    29401 attgtaggca aagagtgggc tgactggttt tctttcgtga atacggacga tagcatcacc
    29461 aattaactca ctagcagtga tgtagcatac atttttagga gttttttctt ttgttgctac
    29521 tgaatcagtc acaagaattt ctttaatatt agtattgtca agaagttcag cagctccctc
    29581 gacgaagaga ccgtggctag aaacagcata aatttctgta gctccttcac gttcaacgat
    29641 tttagaagct tcagagaagg tacgtcctgt atttaaaata tcatcaatca agatagcttt
    29701 cttaccttca acatcaccaa taatataacc ttcgttacga gttgcatcgt cttgagggta
    29761 gtcgataatg gcgataggag catcaagata ttcagccagg ctacgcgcac gtttgacacc
    29821 tgaattttta gggctaacga caacaacatc tgaaccaagc aatcctttat cgcagtaatg
    29881 ttttgcgaat aggggaacag tgaaaagatt atccactgga atatcaaaga aaccttgaac
    29941 ctgaacggca tgcaaatcaa gagtcaggat acgatcaact ccagccttaa ccagcatatt
    30001 ggcaactagt tttgctgtaa gtggctcacg aggacaagca atgcggtctt gacgtgcata
    30061 gccaaaatat ggaaggacaa cgttgatact gtgggcactt gcacgcacac aagcatcgac
    30121 catgattaac aattccatta ggtggttgtt gacagggaaa cttgttgatt ggatgatgta
    30181 aacatcataa ccacggacac tttcttcgat atttacttgg atttctccgt ctgaaaattg
    30241 acgtgatgat agttttccaa gtgggacacc aacagcttgg gcaatttttt gtgcaatctc
    30301 ttggttagag ttgagtgcga aaagtttcat gttttttcta tctgacatta tagaccgtcc
    30361 tctgtaaact ttataaatcc tagttatatt taccttacat atatgaactg ggatttgtgt
    30421 atttttatct tttctatttt accaaaaaat ggagattatt tcagctattt ttcatacttt
    30481 tgacaaatcg aaccaatttt gaaggagctt tttggtagga aatctgattt ttctctaaaa
    30541 attgtcggaa atcctgtttg ccttgctcat gattttccac ttcaagctcc aattcgtaat
    30601 ctgttatatc aaagtatcgg ctctgatcca gtgccatgag accaatagct gttttcattt
    30661 catagcgaag cgttgttaga caaccaagaa cctgccagtt cttactttgg ataccatgtt
    30721 tcgccaattc atccagtact agcccttgag gaagttcttc cttactcaga tagttctcag
    30781 catcttttag ttgtaatttt tggttgtatt ccatgtttcc aacactctgc gggactttga
    30841 gtgtcaactc agcccagtct tcaaaggttc gaatgcgcat agcgactttc ttttctcgca
    30901 gttcaaaatc aggcgtgtcg atgtagtaat ttgtttgaag aacaggagtg acacctgtga
    30961 actggtcttt tagacgattg tattcatctt ttttcaatag tgttttcaat tcaatttcta
    31021 aatgtttcat ttttcttacc tttttttatc gttgaaagcg gatttatggt ataataagca
    31081 ttgtatttat tgtatatgaa tctggagaaa aaatcaaaga tatttttgac ggataatatg
    31141 agaacaaggg agaatatatg accttagaat gggaagaatt tctagatcct tacattcaag
    31201 ctgttggtga gttaaagatt aaacttcgtg gtattcgtaa gcaatatcgt aagcaaaata
    31261 agcattctcc aattgagttt gtgaccggtc gagttaagcc aattgagagc atcaaagaaa
    31321 aaatggctcg tcgtggcatt acttatgcga ccttggaaca cgatttgcag gatattgctg
    31381 gcttacgtgt gatggttcag tttgtagatg acgtcaagga agtagtggat attttgcaca
    31441 agcgtcagga tatgcgaatc atacaggagc gagattacat tactcataga aaagcatcag
    31501 gctatcgttc ctatcatgtg gtagtagaat atacggttga taccatcaat ggagctaaga
    31561 ctattttggc agaaattcaa attcgtactt tggccatgaa tttctgggca acgatagaac
    31621 attctctcaa ctacaagtac caaggggatt tcccagatga gattaagaag cgactggaaa
    31681 ttacagctag aatcgcccat cagttggatg aagaaatggg tgaaattcgt gatgatatcc
    31741 aagaagccca ggcacttttt gatcctttga gtagaaaatt aaatgacggt gtaggaaaca
    31801 gtgacgatac agatgaagaa tacaggtaaa cgaattgatc tgatagccaa tagaaaaccg
    31861 cagagtcaaa gggttttgta tgaattgcga gatcgtttga agagaaatca gtttatactc
    31921 aatgatacca atccggatat tgtcatttcc attggcgggg atggtatgct cttgtcggcc
    31981 tttcataagt acgaaaatca gcttgacaag gtccgcttta tcggtcttca tactggacat
    32041 ttgggcttct atacagatta tcgtgatttt gagttggaca agctagtgac taatttgcag
    32101 ctagatactg gggcaagggt ttcttaccct gttctgaatg tgaaggtctt tcttgaaaat
    32161 ggtgaagtta agattttcag agcactcaac gaagccagca tccgcaggtc tgatcgaacc
    32221 atggtggcag atattgtaat aaatggtgtt ccctttgaac gttttcgtgg agacgggcta
    32281 acagtttcga caccgactgg tagtactgcc tataacaagt ctcttggcgg tgctgtttta
    32341 caccctacca ttgaagcttt gcaattaacg gaaattgcca gccttaataa tcgtgtctat
    32401 cgaacactgg gctcttccat tattgtgcct aagaaggata agattgaact tattccaaca
    32461 agaaacgatt atcatactat ttcggttgac aatagcgttt attctttccg taatattgag
    32521 cgtattgagt atcaaatcga ccatcataag attcactttg tcgcgactcc tagccatacc
    32581 agtttctgga accgtgttaa ggatgccttt atcggtgagg tggatgaatg aggtttgaat
    32641 ttatcgcaga tgaacatgtc aaggttaaga ccttcttaaa aaagcacgag gtttctaagg
    32701 gattgctggc caagattaag tttcgaggtg gagctattct ggtcaataat caaccgcaaa
    32761 atgcaacgta tctattggac gttggagact acgttaccat tgacattccc gctgagaaag
    32821 gctttgaaac cttggaggct attgagcttc cattagatat tctctatgag gatgaccact
    32881 ttctagtctt gaataaaccc tatggagtgg cttctattcc tagtgtcaat cactctaata
    32941 ccattgccaa ttttatcaag ggttactatg tcaagcaaaa ttatgaaaat cagcaggttc
    33001 acattgttac cagactagat agggacactt ctggcttgat gctctttgcc aagcacggtt
    33061 atgcccatgc acgattagac aagcagttgc agaagaaatc tatcgagaaa cgctactttg
    33121 ctttggttaa gggagatgga catttggagc cagaagggga aattattgct ccgattgcgc
    33181 gtgatgaaga ttccattatt accagacgag tggctaaagg cggaaagtat gcccatactt
    33241 catacaagat tgtagcttct tatggaaata ttcacttggt ctatattcac ctgcacactg
    33301 gtcgaaccca tcaaatccga gtccattttt ctcatatcgg ttttcctttg ctgggagatg
    33361 atttgtatgg tggtagtctg gaagatggta ttcaacgtca ggctctgcat tgccattacc
    33421 tatcctttta tcatccattt ttagagcaag acttgcagtt agaaagtccc ttgccggatg
    33481 atttcagtaa ccttattacc cagttatcaa ctaatactct ataaaaactg tctcagagta
    33541 taattattat cttaaaggag aaaactcatg gaagtttttg aaagtctcaa agccaacctt
    33601 gttggtaaaa atgctcgtat cgttctccct gaaggggaag agcctcgtat tcttcaagca
    33661 acaaaacgct tagtaaaaga aacagaagtg attcctgttt tgcttggaaa tcctgaaaaa
    33721 attaaaattt atcttgaaat tgaaggaatc atggatggtt atgaggtcat cgaccctcaa
    33781 cattatcctc aatttgaaga aatggtttct gccttggtgg agcgtcgcaa gggcaaaatg
    33841 actgaagaag atgtacgcaa ggttttggtt gaagatgtca actactttgg tgtgatgttg
    33901 gtttacttgg gcttggttga tggaatggtg tcaggagcga ttcactcaac agcttcaaca
    33961 gttcgcccag ctctacaaat catcaaaact cgtccaaatg taactcgtac ttcaggagcc
    34021 ttcctcatgg ttcgtggtac ggaacgttac ctatttggag actgtgccat taatatcaat
    34081 ccagatgcgg aagccttggc tgaaattgcc atcaactcag caatcacagc taagatgttt
    34141 ggcatcgaac ctaaaattgc catgttgagc tattctacta aaggttcagg gtttggtgaa
    34201 agcgttgata aggtcgttga agcaactaaa attgctcacg acttgcgtcc tgaccttgaa
    34261 atcgatggtg agttgcaatt tgatgcggcc tttgttcccg aaactgcagc tctgaaagct
    34321 ccgggaagca cagtagctgg tcaagcaaat gtcttcatct tcccaggtat cgaggcagga
    34381 aatatcggtt acaagatggc tgaacgcctg ggtggctttg cggctgtagg acctgttttg
    34441 caaggtttaa acaagccagt taatgatctt tctcgtggat gtaatgcaga tgatgtttac
    34501 aagttgaccc tcatcacagc agctcaagca gttcatcaat agtgaaaact ataaagtgat
    34561 atactatgct atactgtagt tatgaaacta tgtacgaaaa gcactgccat taattcctga
    34621 gaactaaatt actgattggt gtcaaaaagg aaaacttcca agcgatgata tcctgtctat
    34681 acacgaccta tagaaatctg taatatacat gtccgtaaaa cgataaattc cctttttgat
    34741 tttaaatgag tatgaaaaga gaattttttg gctctttgtc aactgtagtg ggttgaagtc
    34801 agctaagctc gagaaaggac aaattttgtc ctttcttttt tgatattcag agcgataaaa
    34861 atccgttttt tgaagttttc aaagtttcga aaaccaaagg cattgcgttt gataagtttg
    34921 atgagattat tggtcgcttc caatttggcg tttgaatagg gtagttgaag ggcgttgacg
    34981 attttctctt tgtcctttag aaaggtttta aagacagtct gaaaaagagg atgaacctgc
    35041 tttagattgt cctcaataag cccgaaaaat ttctctggtt ccttattctg gaagtgaaac
    35101 agcaagagct gatagtggtg tttcaagtct tgtgaatagc tcaaaagctt gtttaaaatc
    35161 tctttattgg ttaagtgcat acgaaaagta ggacgataaa aacgtttatc actcagttta
    35221 cggctatcct gttgaatgag tttccagtag cgcttgatag ccttgtattc atgggatttt
    35281 cgatgaaact gattcatgat ttggacatgc acacgactca tagcacggct aagatgttgt
    35341 acaatgtgaa agcgatcaag aacgatttta gcattcggga gtgaaacagt ctgggagact
    35401 gtttcagcct gagcctagaa atttgaaagc gaagctgttt agccaagcca tagtaagggc
    35461 taaacatatc catagtaatg attttgacgc gacatcggac ggctctatcg tagcgaagaa
    35521 agtgatttcg aatgatagct tgtgttcttc cctcaagaac agtgatgata ttgagcttgt
    35581 caaaatcttg cgcaataaag ctcatctcca tctcccgatt gaaacagtca ctccccggac
    35641 tgtttcaacg tcccaagaca taatctcagg cagatttcta aaattacact caaagtggaa
    35701 gtcattgagc ttacgaataa cagttgaagt tgagatgaaa agctgatggg caatatcagt
    35761 catagaaatc ttttcaatta acttttgagc aatcttttgg ttgatgatac gagggatttg
    35821 gtgatttttc ttgacgatag aagtttcagc gaccatcatt tttgaacagt gatagcactt
    35881 gaatcgacgc tttctaagga gaattctagt aggcatacca gtcgtttcaa gataaggaat
    35941 tttagaaggt ttttgaaagt catatttctt caattgattt ccgcactcag ggcaagatgg
    36001 ggcgtcgtag tccagtttgg cgat
//
LOCUS       DAVLCS010000019        35771 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLCS010000019 DAVLCS010000000
VERSION     DAVLCS010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35771
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.019"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(1..459)
                     /locus_tag="VXC78_001072"
                     /pseudo
     CDS             complement(1..459)
                     /locus_tag="VXC78_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            454..708
                     /locus_tag="VXC78_001073"
     CDS             454..708
                     /locus_tag="VXC78_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0583168.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            1052..2386
                     /gene="trmFO"
                     /locus_tag="VXC78_001074"
     CDS             1052..2386
                     /gene="trmFO"
                     /locus_tag="VXC78_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV0583169.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            2470..3207
                     /locus_tag="VXC78_001075"
     CDS             2470..3207
                     /locus_tag="VXC78_001075"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV0583170.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            3216..3773
                     /gene="frr"
                     /locus_tag="VXC78_001076"
     CDS             3216..3773
                     /gene="frr"
                     /locus_tag="VXC78_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV0583171.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3833..4687
                     /gene="cvfB"
                     /locus_tag="VXC78_001077"
     CDS             3833..4687
                     /gene="cvfB"
                     /locus_tag="VXC78_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV0583172.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPVLKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4696..4911
                     /locus_tag="VXC78_001078"
     CDS             4696..4911
                     /locus_tag="VXC78_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV0583173.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4997..5965
                     /locus_tag="VXC78_001079"
     CDS             4997..5965
                     /locus_tag="VXC78_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV0583174.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(5943..6122)
                     /locus_tag="VXC78_001080"
     CDS             complement(5943..6122)
                     /locus_tag="VXC78_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583175.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            6158..6658
                     /locus_tag="VXC78_001081"
     CDS             6158..6658
                     /locus_tag="VXC78_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0583176.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVIDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6661..6921
                     /locus_tag="VXC78_001082"
                     /pseudo
     CDS             6661..6921
                     /locus_tag="VXC78_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(7288..7614)
                     /locus_tag="VXC78_001083"
     CDS             complement(7288..7614)
                     /locus_tag="VXC78_001083"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583177.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(7560..7973)
                     /locus_tag="VXC78_001084"
     CDS             complement(7560..7973)
                     /locus_tag="VXC78_001084"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV0583178.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASMRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(7974..8399)
                     /locus_tag="VXC78_001085"
     CDS             complement(7974..8399)
                     /locus_tag="VXC78_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV0583179.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            8576..9145
                     /locus_tag="VXC78_001086"
     CDS             8576..9145
                     /locus_tag="VXC78_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0583180.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTPETNRAVIELAFEKIGMNKLVALYDKDNSASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            9213..9863
                     /locus_tag="VXC78_001087"
     CDS             9213..9863
                     /locus_tag="VXC78_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV0583181.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            9847..12087
                     /locus_tag="VXC78_001088"
     CDS             9847..12087
                     /locus_tag="VXC78_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV0583182.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPLSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGWNSW
                     KIESVR"
     gene            12229..12453
                     /locus_tag="VXC78_001089"
     CDS             12229..12453
                     /locus_tag="VXC78_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583183.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYYSYSEYPVGSGWNYARYEVINYYTGGY"
     gene            12485..13072
                     /locus_tag="VXC78_001090"
     CDS             12485..13072
                     /locus_tag="VXC78_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583184.1"
                     /translation="MLRLTHVTLKTRQVILQDADFTFKKGRVYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            13076..14257
                     /locus_tag="VXC78_001091"
     CDS             13076..14257
                     /locus_tag="VXC78_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583185.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVVVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFK
                     V"
     misc_feature    14417..14548
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14564..15094
                     /gene="infC"
                     /locus_tag="VXC78_001092"
     CDS             14564..15094
                     /gene="infC"
                     /locus_tag="VXC78_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV0583186.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            15127..15327
                     /gene="rpmI"
                     /locus_tag="VXC78_001093"
     CDS             15127..15327
                     /gene="rpmI"
                     /locus_tag="VXC78_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV0583187.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            15379..15738
                     /gene="rplT"
                     /locus_tag="VXC78_001094"
     CDS             15379..15738
                     /gene="rplT"
                     /locus_tag="VXC78_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV0583188.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15796..16176
                     /locus_tag="VXC78_001095"
     CDS             15796..16176
                     /locus_tag="VXC78_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0583189.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16426..17226
                     /locus_tag="VXC78_001096"
     CDS             16426..17226
                     /locus_tag="VXC78_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV0583190.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            17237..18175
                     /locus_tag="VXC78_001097"
     CDS             17237..18175
                     /locus_tag="VXC78_001097"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV0583191.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            18217..20250
                     /locus_tag="VXC78_001098"
     CDS             18217..20250
                     /locus_tag="VXC78_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEV0583192.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(20311..21966)
                     /gene="pavA"
                     /locus_tag="VXC78_001099"
     CDS             complement(20311..21966)
                     /gene="pavA"
                     /locus_tag="VXC78_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV0583193.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            22071..22568
                     /gene="ybeY"
                     /locus_tag="VXC78_001100"
     CDS             22071..22568
                     /gene="ybeY"
                     /locus_tag="VXC78_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV0583194.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22549..22944
                     /locus_tag="VXC78_001101"
     CDS             22549..22944
                     /locus_tag="VXC78_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV0583195.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22961..23860
                     /gene="era"
                     /locus_tag="VXC78_001102"
     CDS             22961..23860
                     /gene="era"
                     /locus_tag="VXC78_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV0583196.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23909..24733
                     /gene="mutM"
                     /locus_tag="VXC78_001103"
     CDS             23909..24733
                     /gene="mutM"
                     /locus_tag="VXC78_001103"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV0583197.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24733..25338
                     /locus_tag="VXC78_001104"
     CDS             24733..25338
                     /locus_tag="VXC78_001104"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV0583198.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFEQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            25325..26524
                     /locus_tag="VXC78_001105"
     CDS             25325..26524
                     /locus_tag="VXC78_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HEV0583199.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26524..26673
                     /gene="rpmG"
                     /locus_tag="VXC78_001106"
     CDS             26524..26673
                     /gene="rpmG"
                     /locus_tag="VXC78_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0583200.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKEKKVTL
                     HLESK"
     gene            26713..26946
                     /gene="secG"
                     /locus_tag="VXC78_001107"
     CDS             26713..26946
                     /gene="secG"
                     /locus_tag="VXC78_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV0583201.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            27048..29402
                     /gene="rnr"
                     /locus_tag="VXC78_001108"
     CDS             27048..29402
                     /gene="rnr"
                     /locus_tag="VXC78_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV0583202.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIVEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGIGRGSNRRSDKKEDKRKS
                     GRSNDKRKYSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            29365..29832
                     /gene="smpB"
                     /locus_tag="VXC78_001109"
     CDS             29365..29832
                     /gene="smpB"
                     /locus_tag="VXC78_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV0583203.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29848..30708
                     /gene="tehB"
                     /locus_tag="VXC78_001110"
     CDS             29848..30708
                     /gene="tehB"
                     /locus_tag="VXC78_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV0583204.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30781..31734
                     /gene="coiA"
                     /locus_tag="VXC78_001111"
     CDS             30781..31734
                     /gene="coiA"
                     /locus_tag="VXC78_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV0583205.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            31753..33555
                     /gene="pepF"
                     /locus_tag="VXC78_001112"
     CDS             31753..33555
                     /gene="pepF"
                     /locus_tag="VXC78_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0583206.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            33557..34270
                     /locus_tag="VXC78_001113"
     CDS             33557..34270
                     /locus_tag="VXC78_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV0583207.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            34337..35278
                     /gene="prsA"
                     /locus_tag="VXC78_001114"
     CDS             34337..35278
                     /gene="prsA"
                     /locus_tag="VXC78_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV0583208.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(35395..35736)
                     /locus_tag="VXC78_001115"
                     /pseudo
     CDS             complement(35395..35736)
                     /locus_tag="VXC78_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        10748 a         6653 c         8047 g        10323 t
ORIGIN      
        1 acaattctcc cttgacttgt gacaatcgct tgagccttca tagcgtagca tttcttttta
       61 ccagaataat tcgctaattc tttttttagg gcgattgatt tttacttccg tcgcatcaat
      121 aatcattacc gtgtcctcag aactgagagg agttcttgaa atcgtaacac cactttgaac
      181 aagagttact tcaacccatt ggctccgacg gattaagttg ctttcgtgaa taccaaaatc
      241 agccgcaatt tgttcataag ttcgatattc tcgcacatat tgaagagtgg ccataagaag
      301 gtcttctagg cttaatttag gttttcgtcc accttttgcg tgtttaagtt gataagctgt
      361 ttttaataca gctaatatct cttcaaaagt cgtgcgctga acaccaacaa gacgcttaaa
      421 tcgtgcatca gttagttgtt tacttgcttc atcattcata gaactactat accatatttt
      481 gtttcgcagg aagtctattg gaaagtaaga aatattgaag ctgaggcgat tagaagaaat
      541 tgtgagcgtg gtgctatttt ttcaggtaaa ataaaacatc acgaagattc tcagtttaaa
      601 ggagaccact atgttgaatg ttatgctgtt ttagataata cggttatagc aagagataga
      661 ataacagtcc ctatcgatcc gttatgtgga aaagatttta tagagtagca tataattgat
      721 tcttaactgg aatactctct atctctttac atcaagaaaa tgactaaaca gggaagtttg
      781 ccttcttccc tttttttgtt atactagtag aagaaaaaaa tagaaagatt tgtgggagtg
      841 aaaaagtccg ggggactttt tcagcttgag ccaagaaatt cgagagcgag gaaagtctgg
      901 gggacttttt cagcttgagc caagaaattc gagagcgagg aaagtctggg ggactttttc
      961 agcctgagcc aagaaactcg aaatctcgta agtctgattg gctttttcaa tgtgaatctt
     1021 aacttcacac tcccaaagag gtattagtgt cgtgtctcaa tcttatatca atgttatcgg
     1081 tgctggtttg gcaggttctg aagcagctta ccaaatcgca gagcgtggta ttccagttaa
     1141 actttatgaa atgcgtggtg tcaagtctac accccagcat aaaacagaca attttgctga
     1201 gttggtttgt tccaattctt tgcgtgggga tgctttgaca aatgcagttg gtcttctcaa
     1261 ggaagaaatg cgtcgcttgg gttctgttat cttggaatct gctgaggcta cacgtgttcc
     1321 tgccggtgga gcccttgcgg tggatcgtga tggtttctct caaatggtga ccgaaaaagt
     1381 ggtcaaccac cccttgattg aagtggtgcg tgatgaaatt acagaattgc caacagatgt
     1441 tattacagtt gtggcgactg gtcccttgac tagcgatgcc ctggctgaaa agattcatgc
     1501 ccttaataat ggcgatggct tctatttcta cgatgcagca gcgcctatta tcgatgtcaa
     1561 cactatcgat atgagtaagg tctatctcaa atctcgttat gataagggag aagcagccta
     1621 tctcaatgct ccaatgacca agcaagagtt tatggatttc catgaagcct tggtcaatgc
     1681 ggaagaagca ccgctcaatt cttttgaaaa agaaaagtac tttgaaggat gtatgccaat
     1741 cgaagttatg gccaaacgtg gcattaaaac tatgctttat ggccctatga agccagtcgg
     1801 tcttgagtat ccggacgact acacaggacc tcgtgatgga gaatttaaaa caccttatgc
     1861 ggttgtgcaa cttcgtcagg ataatgcagc tggtagccta tacaatattg ttggtttcca
     1921 gacccacctc aaatggggag aacaaaagcg tgtcttccaa atgattccgg gtcttgaaaa
     1981 tgcggagttt gtccgttatg gtgtcatgca tcgcaattct tacatggatt caccaaatct
     2041 tcttgagcag acttaccgtt ccaagaaaca accaaatctc ttctttgctg gtcagatgac
     2101 gggggtggaa ggctatgttg agtcggcggc ttcgggctta gttgcgggaa ttaacgcagc
     2161 tcgtctcttc aaggaagaaa gcgaggttat tttccccgag acgacagcga ttggaagctt
     2221 agctcattac attacccatg ccgacagcaa acatttccaa ccaatgaatg tcaattttgg
     2281 gatcatcaag gagttggaag gcgagcgtat ccgtgataag aaggctcgtt atgaaaaaat
     2341 tgcagagcgt gcccttgccg acttagagga atttttgact gtctaatttt tttgaaagaa
     2401 ttgttcatga tactataaaa atcttagaaa ttgtgataaa ataggtagga tgaaagaagg
     2461 agagtgaaaa tggcgaatcc caagtataaa cgtattttaa tcaagttatc aggtgaagcc
     2521 cttgccggtg aacgtggcgt agggattgat atccaaacag ttcaaacaat cgcaaaagag
     2581 attcaagaag ttcatagctt aggtatcgaa attgcccttg ttattggtgg aggaaatctc
     2641 tggcgtggag aacctgcagc agaagcaggt atggaccgtg ttcaggcaga ttacactgga
     2701 atgcttggga ctgttatgaa tgctcttgtg atggcagatt cattgcaaca agttggggtt
     2761 gatacgcgtg tacaaacagc tattgctatg caacaagtgg cagagcctta tgtccgtgga
     2821 cgtgcccttc gtcaccttga aaaaggccgt atcgttatct ttggtgctgg aattggttca
     2881 ccatacttct cgacagatac aacagcggcc cttcgtgcag ctgaaatcga agcagatgcc
     2941 atcctcatgg ctaaaaatgg cgtcgatggt gtgtacaatg ccgatcctaa gaaggacaag
     3001 acagccgtta agtttgaaga attgacccac cgtgatgtta tcaacaaagg tcttcgtatc
     3061 atggactcaa cagcctcaac cctctcaatg gacaacgaca ttgacttggt tgtcttcaac
     3121 atgaaccaat caggcaacat caaacgtgtt gtatttggtg aaaatatcgg aacaacagtt
     3181 tcaaataata tcgaagaaaa ggaataagaa agaatatggc taacgtaatt attgaaaaag
     3241 ctaaagagag aatgacccag tctcaccaat cacttgctcg tgaatttggt ggtatccgtg
     3301 ctggtcgtgc caatgcaagc ttgcttgacc gtgtacatgt agaatactat ggagtcgaaa
     3361 ctcctcttaa ccaaatcgct tcaattacga ttccagaagc gcgtgttttg ttggtaacac
     3421 catttgacaa gtcttcattg aaagacatcg aacgtgcctt gaacgcttct gatcttggta
     3481 tcacaccggc taatgacggt tctgtgattc gcttggttat cccagctctt acagaagaaa
     3541 ctcgtcgtga ccttgctaaa gaagtgaaga aggtcggcga aaatgctaaa gtggctgtcc
     3601 gcaatatccg tcgcgatgct atggacgaag ctaagaagca agaaaaagca aaagaaatca
     3661 ctgaagacga attgaagact cttgaaaaag atattcaaaa agtaacagac gatgctgtta
     3721 aacacatcga cgacatgact gctaacaaag agaaagaact tttggaagtc taaaaataaa
     3781 cagaaaaact cagttggcat tgctggctga gttttattcg aaagaaggaa atatgaatac
     3841 aaatcttgca agttttatcg ttggactgat catcgatgaa aatgaccgtt tttactttgt
     3901 gcaaaaggat ggtcaaacct atgctcttgc taaggaagag ggccaacata cagtagggga
     3961 tacggtcaaa ggttttgcat acacggatat gaagcaaaaa ctccgcctga caaccttaga
     4021 agtgactgcc actcaggacc aatttggttg gggacgtgtc acagaggttc gtaaggactt
     4081 gggtgtcttt gtggatacag gccttcctga caaggaaatc gttgtgtcac tcgatattct
     4141 ccctgtgctc aaggaactct ggcctaagaa gggcgaccaa ctctacatcc gtcttgaagt
     4201 ggataagaaa gaccgtatct ggggcctctt ggcttatcaa gaagacttcc aacgtctcgc
     4261 tcgtcctgcc tacaacaaca tgcagaacca aaactggcca gccattgttt accgtctcaa
     4321 gctgtcagga acttttgttt acctaccaga aaataatatg cttggtttta ttcatcctag
     4381 cgagcgttac gcagagccac gtttggggca agtattagat gcgcgcgtta ttggtttccg
     4441 tgaagtggac cgcactctga acctctccct caaaccacgc tcctttgaaa tgttggaaaa
     4501 cgatgctcag atgattttga cttatttgga aagtaatggc ggtttcatga ccttaaatga
     4561 taagtcatct ccagacgaca tcaaggcaac ctttggcatt tctaaaggtc agttcaagaa
     4621 agctttaggt ggtcttatga aggctggtaa aatcaagcag gaccagtttg ggacagagtt
     4681 gatttaggga ggcttatgag aaaatcattt tacacttggc tcatgaccga gcgcaatcct
     4741 aaaagtaaca gtcccaaagc aattttggca gacctcgctt ttgaagaggc agcttttcca
     4801 aaacatacag atgattttga tgaggtcagt cgctttttgg aggagcatgc cagtttctct
     4861 tttaacctag gagattttga cagcatttgg caggaatatc tagaacacta gcatttattc
     4921 attgggtttg ggctagtaat ttctccatcc ctctgctata ataaaaagaa ataaaaggat
     4981 tagagaggtt ctttatttga aggaacattc aatagacatt caactgagtc atccagatga
     5041 cctgtttcat ctttttggtt ccaatgaacg ccatcttcgt ttgatggaag aagagcttga
     5101 tgttgtgatt catgctcgta cggagattgt ccaggttttg ggagaagagt ctgcctgtga
     5161 ggaagcccgt caagttattc aggctttgat ggtcttggta aatcgtggga tgaccgttgg
     5221 tacgccagat gtagtcactg cgattagcat ggtcaaaaat gatgaaattg acaagtttgt
     5281 cgccctttac gaagaagaaa ttatcaaaga taatactggg aaacctatcc gtgtcaaaac
     5341 cctagggcaa aagctttatg tggacagtgt caaacagcat gatgtgacct ttggaattgg
     5401 gccagcaggt acagggaaga ccttccttgc agtgaccttg gcagtgactg cccttaaacg
     5461 tgggcaagtc aagcgaatta tcctaactcg tccagcggtg gaagcgggag agagtcttgg
     5521 atttcttccg ggtgatctta aggagaaggt ggatccttac cttcgtcctg tttacgatgc
     5581 cttgtatcag attctgggga aagaccaaac aactcgactc atggagcgtg aaattatcga
     5641 gattgcgccc cttgcctata tgcgtggacg gaccttggat gatgcctttg tcattctcga
     5701 tgaggcgcaa aatacgacca tcatgcagat gaagatgttc ttgactcgtt taggttttca
     5761 ttctaagatg attgtcaatg gagatattag tcagattgac ctgccacgta atgtcaagtc
     5821 cggtttgatt gatgctcaag agaaactcaa gaacatccat cagattgact ttgttcattt
     5881 ttcagccaag gatgtggttc gccatccagt tgtcgctcag attatccgag cctatgaata
     5941 ttctactgaa gttgcacacg actgattttg aggaagtttg cctgcaaaag aatatacttt
     6001 tgagagagga aaatccagtt gtataggcta aaggttttat ccaaaggttt gagacaacga
     6061 ttaggcacga tggaaagaac ttttatgtgg ctgatgacga tcagtgcatc ttcctgtgtc
     6121 ataatcacag ggcacaagaa agtaggaatt tgaaaagatg attgaccaac tatctaagta
     6181 ttacagttgt aggatactaa ctgaaaagga tattccaagt attttatctt tatatgaaag
     6241 taatcctctg tattttcagc attgtccacc agagccaaat tttgcaactg taaaagagga
     6301 catgctttgt ctacctgaag gtaaagctaa ggctgataag ttttttgttg gattttggaa
     6361 tggatctgac cttgtggctg ttatagattt tgtctatgca catcctgatg aggagactgt
     6421 ttttattggt ttgtttatgg ttgatcaagc ctatcagagg aaagggattg gtagtcatat
     6481 tgtgacagaa gcactagctt attttgctaa gaactttcga aaggcacgtt tggcttatgt
     6541 taagggaaat ccgcaatctc agcatttttg ggaaaagcag ggctttaaat caattggatg
     6601 cgaggttaag caagaactct atacggttgt tatcgctgaa cagagcctag aagattagaa
     6661 atggcatcaa gtaagaacta tttggaattt gttttggaac aattatcagg attagatgat
     6721 gtgacttacc gttccatgat tggggagtat attctttact tccgcggcaa gattattggc
     6781 ggcatttatg acgatcgctt tttagttaaa cccgtgcaag cagtcttaga taagattgac
     6841 caatcttctt ttgagtttcc atacaaaggt gccaaagaaa tgatttgagt ggaagaactt
     6901 gataataaga tgtttctata agacctgatt ttagctatgt ataaccaact gccaacgccc
     6961 aaacctaaaa agaaaaagca agggtgaacg aagtaaaaaa gaagtctgct aaggccctgt
     7021 ctttgcacgg gtaaaatttt atatataaaa agaagctggg actaaagagc tcagcttcct
     7081 ttggtttata taattgtcat tacaagacga agtggttggg cgaaactctg ttgactttat
     7141 tcaatttaga gtttcttatg cacaattgag tctggaacga aagtctccag ttgcaaagta
     7201 tacagtacaa taaaccaacg atgtaatagc tgatgacaca aagcacagtg ggtaggactt
     7261 gcgaagtcac ccttttcttt tcaaaattta tactaaatca ttgatatcag tgtagtcacg
     7321 attaagtcct tgagcaactg gtaggctagt caagtaacct tgataagtgg tcacaccttg
     7381 acgcaagcct tcatcttcag agattgcttg tgcgaatcct ttgccagcca aagcttcgat
     7441 ataaggaaga gtgacattgg ttagggcgat ggttgaagtg cgggcaaccg caccagggat
     7501 attggcaacg gcatagtgga gaacaccgtg tttttcatag acgggttcat cgtgcgttgt
     7561 cacacggtca gctgtttcga taacgccacc ttggtcaaca gcaacgtcaa cgatacagag
     7621 cctggacgca tttgtttgac catctcatct gtcaccaatt ccggtgcttt tgcaccaggg
     7681 atgagaatgg ctccaatcac cacatcagca tctctcatac ttgcttcaat gttgaatgaa
     7741 ttagatataa gagtttgaat ttgacttcca aagacttctt ctagaactga gagacgcttg
     7801 gcactaatat ctaaaatagt cacttgagca ccaagaccaa gggcgatgcg ggcagcatgt
     7861 gtaccgacga caccatcacc gatgatagtt acttttcctt ttggaacacc tggtacacca
     7921 ccaggtagaa caccagagcc accagcttgc ttagtaagga agtgagctcc gatttaaaca
     7981 gccatacgac ctgcaacctc actcatagga acgaggagcg gtagttgtcc ttgattgtca
     8041 cgaacagttt cataggcaat tcctgttgtt tttgctgcta acatagcatc tgctaattct
     8101 ggagcagcgg ccatgtgcaa gtaggtgaag agaagaagat cgtcgcgcaa gtaaccgtat
     8161 tcagaactta aaggttcttt tactttcaca accaactctg ctgcccaagc ttcaccagca
     8221 gtagcgacaa tctcagctcc ttgcttttga tagtcagcat cagtaaagcc agaaccgaga
     8281 ccagcatttg tttcgataag gacacgatga ccacgactaa ctaagctatg aacacctgca
     8341 ggtgtgaggg cgacacggtt ttcgttattt ttaatttctt ttgggattcc gattaacatt
     8401 gagataacct acctttcaat tgacggtctt gttttggttg tcacattcca gttcataaat
     8461 caaaaatgtg acggtttcat tgtatatgaa accgcttcaa aaatcaagaa aaacttgtca
     8521 tccaaatttt tttatgctag actagtgaaa atcaagctct aatggaggga aaagtatgga
     8581 atcaatattt gtgaaatttg cccagtatcc gtctatagaa acggagcgtt tattgcttag
     8641 acctgtaact ttggatgatg cggaagcaat gtttgactat gcctcggaca agggtaatac
     8701 acgttacact tttccaacca atcaaagctt ggaagaaacc aagaataaca ttgctcagtt
     8761 ctacttggct aatcccttgg gacgttgggg gattgaatta aaagataacg gcaagtttat
     8821 cggaactatt gacttacaca agattgatcc tgttcttaag aaggcagcta ttggctacat
     8881 tatcaataaa aagtattgga atcaaggatt aacgccagaa accaatcgtg ctgtgattga
     8941 gctagctttt gagaagatag gaatgaataa gttagttgct ttatacgata aggacaattc
     9001 tgcgtcagga aaggtcatgg agaaatcagg catgcgtttt tcccatgcag aaccatatgc
     9061 ttgtatggac cagcatgaaa aaggccgaat cgtgacaaga gttcattatg tcttgaccaa
     9121 ggaagactat tttgcaaata aataagcagt tgaaaagaaa tttttcgact gttttttctt
     9181 cctcttacga ataatctaag agaggagaaa atatggaagc aattatcgag aaaatcaaag
     9241 agtataaaat catcgtcatc tgtactggtc tgggcttgct tgtaggcgga tttttcctgc
     9301 taaagccagc tccacaaaca cctgtaaagg aaacgaattt gcaggctgaa gttgcagctg
     9361 tttccaagga tttggtatcc gaaaaggaag tgaacaagga agagaaggaa gaaccccttg
     9421 aacaagatct aatcacagta gatgtcaaag gtgctgtcaa atcgccaggg atttatgact
     9481 tgcctgtagg tagtcgagtc aatgatgctg ttcagaaggc tggtggcttg acagagcaag
     9541 cagacagcaa gtcgctcaat ctagctcaga aagttagtga tgaggctctg gtttacgttc
     9601 ctactaaggg agaagaagca gttagtcaac agactggttc ggggacagct tcttcaataa
     9661 gcaaggaaaa gaaggtcaat ctcaacaagg ccagtctgga agaactcaag caggtcaagg
     9721 gactgggagg aaaacgagct caggacatta tcgaccatcg tgaggcaaat ggcaagttca
     9781 agtcagtaga cgagctcaag aaggtctctg gcattggtgg caaaacaata gaaaagctta
     9841 aagactatgt tacagtggat taagaatttc tctattcccc taatttacct gagttttcta
     9901 ttactttggc tttattacgc tattttctca gcatcttatc ttgctttgtt gggctttgtt
     9961 tttctgctag tctgtctctt tatccaattt ccgtggaaat ctgctggtaa agttctaata
    10021 atttgcggaa tctttggatt ttggtttgtt tttcaaaatt ggcaacagag tcaagcgagt
    10081 caaaatctgg cggattctgt tgaaagggta cggattttgc ctgatactat taaggttaat
    10141 ggtgatagtc tatcctttcg tggcaagtct aacggtcgtg ctttccaagt ctattataaa
    10201 ctccagtccg aggaggagaa agaagccttt caagctttaa ccgacctgca tgagatagga
    10261 ctagaaggga agctttcgga gccagaaggg cagagaaatt ttggtggctt taattaccaa
    10321 gcctatctga agactcaggg aatttaccag actctcaata tcaaaaaaat ccagtcactt
    10381 caaaagattg gcagttggga tataggagaa aacttgtcca gtttacgtcg aaaggctgtg
    10441 gtttggatta agacgcactt tccagaccct atgcgcaatt acatgacagg actcttgctg
    10501 ggacatctgg acaccgactt tgaggagatg aatgagcttt attccagtct aggaattatc
    10561 cacctctttg ccctatctgg tatgcaggta ggttttttca tgaatggatt taagaaactt
    10621 ctcttgcgat tgggcttgac ccaagaaaag ttgaaatggc tgacttatcc cttttccctt
    10681 atctatgcgg gactaactgg attttcagca tcggttattc gcagtctctt gcaaaagcta
    10741 ctggctcaac atggggttaa gggcttggat aattttgcct tgacggtgct tgtcctcttt
    10801 attgtcatgc caaacttttt cttgacagca ggaggagtct tgtcctgcgc ttatgctttt
    10861 atcctgacca tgaccagcaa agaaggggag gggctcaagg ctgttactag tgaaagtcta
    10921 gtcatctcct tgggcatatt gcccattcta tccttctatt ttgcggaatt tcaacctttg
    10981 tctatccttt tgacctttgt cttttccttt ctatttgact tgaccttctt accgctcttg
    11041 tctattttat ttgtcctttc ctttctctat ccagtcattc agctgaactt tatctttgaa
    11101 tggttggagg gcattattcg cttggtgtca caggtgacaa gtagacctct ggtctttgga
    11161 caacccaatg catggttttt aatcctattg ttaatttcct tggctttggt ctatgatttg
    11221 agaaaaaaca ttaaaaagct aacggtattg tgcttattga ttacagggct ctttctcctg
    11281 accaagcatc cactggaaaa tgaaatcacc atgctggatg tggggcaagg agaaagtatt
    11341 ttcctacggg atgtaactgg gaaaaccatt ctcatagatg taggtggtaa ggcagaatct
    11401 tataagaaaa tcgaaaaatg gcaagaaaaa atgacgacca gcaatgccca gcgaaccttg
    11461 attccctatc tcaaaagtcg aggagtagct aagattgacc agctaatttt gactaacacg
    11521 gacaaggaac atgtcggaga tttgttagag gtgaccaagg ctttccatgt aggggagatt
    11581 ttagtatcaa aaggcagttt gaagcagaag caatttgtgg tagaactaca ggcgactcaa
    11641 acaaaggtgc gtagtatgac agtaggggag aacttgccca tttttggaag tcagttagaa
    11701 gttctatccc caaggaaaat gggagatgga ggacacgatg ataccctagt tctgtatggg
    11761 aaattcttgg ataagcaatt tctcttcacg ggaaatttgg aggagaaagg agagaaggac
    11821 ttgctgaagc actatccaga cttgaaagta aatgttttga aagctagcca acatggcaat
    11881 aaaaaatcat caagtccagc ctttctagaa aaactcaaac cagagcttac tcttatctca
    11941 gttggaaaga gcaatcgaat gaaactcccc catcaggaaa cattgacacg actggaaggt
    12001 atcaatagca aagtttaccg aactgaccag caaggagcta tacggtttaa aggttggaat
    12061 agttggaaaa tcgaaagtgt tcgataggaa agataaatgt tgtagattag tgaaataaac
    12121 taaaaatttg ttgcataata atgataaaaa tggtataatg aaaacgtatt caatactgag
    12181 gatataaaat cattaaaaat tagcaaaaat cgtttaatta gttagtttat gattattggt
    12241 ctttttcagt ccagtatatc tgctgtgaca gtcactaaaa gttacaagta tgattggaat
    12301 acggtttggg aatatagtac taactatcac gaccatcagt atgcttggat tccgtcatgg
    12361 tctcgttatt acagctattc tgagtatcca gttggttctg gctggaacta cgctcgttat
    12421 gaggtcataa actactatac tggaggttat taatccttaa agagtgagaa aaggagggct
    12481 ggatatgtta aggcttactc atgttaccct aaaaacgcga caagtcatct tgcaagatgc
    12541 ggattttacc tttaaaaagg gtagggttta tggtcttctt gctatcaatg gctcgggaaa
    12601 gacgacacta ttccgagcta tgagcaagtt gcttcccctt agtagtggac acatcgcagt
    12661 tcctccttct ttgttttatt atgagagcgt tgaatggctg gatggaaact taagtgggat
    12721 ggactacctt cgtctcataa aaaacatctg gaagtcagac ctaaacttga gagatgaaat
    12781 cgcctactgg gaaatggctg actatatcag tcttcccatc cgcaagtatt ccttaggcat
    12841 gaagcaacgc ttggtgattg ctatgtattt tctcagtcag gccaaatgct ggctcatgga
    12901 tgagattaca aatggcttag acgagtatta tcgacagaag ttttttgata ggctagcaca
    12961 aatcgataga caagaacagc tggttctttt aagttcccac tataaggaag agttggttga
    13021 tatctgcgat agagtagtaa ccattcatca ggggcagata gaagaggttt agtttatgaa
    13081 agatgttagt ctatttttat tgaaaaaagt tttcaaaagt cgtttaaact ggattatctt
    13141 acttttattt gcatctgtac tcggtgttac cttttattta aatagtcaga ctgcaaactc
    13201 acacagcttg gagagcaggt tggaaagtcg cattgcagcc aacgagaggg ctatcaatga
    13261 aaatgaagag aaactctccc aaatgtctga taccagctcg gaggaatacc agtttgctaa
    13321 aaataattta gacgtgcaaa aaaatctttt gacgcgaaag acagaaattc taactttact
    13381 aaaagaaggg cgctggaaag aagcctacta tctgcagtgg caagatgaag agaagaatta
    13441 tgaatttgta tcaaatgacc cgactgctag ctctggctta aaaatggggg ttgaccgcga
    13501 acggaagatt taccaagccc tgtatccctt gaacataaaa gcacatactt tggagtttcc
    13561 gacccacggg attgatcaga ttgtctggat tttagaggtt atcatcccaa gcttgtttgt
    13621 ggttgcgatt atttttatgc taacacaact atttgcagaa agatatcaaa atcatctgga
    13681 cacagctcac ttatatcctg tttcaaaagt gacatttgca atatcctctc ttggagttgt
    13741 agtgggatat gtaactgtgc tgtttatcgg aatctgtggc ttttcttttc tagtgggaag
    13801 tctgataagt ggttttggac agttagatta tccctaccca atttatagct tagtgaatca
    13861 agaagtaact attgggaaaa tacaagatgt attatttcct ggcttgctct tagctttctt
    13921 agcctttatc gtcattgtgg aagtcgtcta cttgattgct tactttttca agcaaaaaat
    13981 gcctgtcctc tttctttcac tcattgggat tgttggctta ttgtttggca tccaaacaat
    14041 tcagcctctt caaaggattg cacatctgat tccctttact tacttgcgtt cagtggagat
    14101 tttatctgga agattatcta agcagattga taatgtcgat ctaaattgga gcatggggat
    14161 ggtcttactt ccttgcctga ttatcctttt gttagtgggg attctattta tcgaaagctg
    14221 gggaagttca cgtaaaaagg aagtttttaa agtttagttt tcctataggg aagctaaaga
    14281 aaaactaaca tagggagaga atcaacttgg ttctctcttt ttgattcgaa aaccaaacca
    14341 aaatacaaac acaaactttt caaaaaataa ctttttatct tgacaagagc tagaaaactt
    14401 ggtatcatat aaaagttgag aaaagcagaa gtgagagctt ctcgccttgt gacattaagt
    14461 tgcctggccc tacggatgaa aagtttcgaa gaaacgctat cataacgtgc gggcttgtat
    14521 atttacaagt ccgctattgt ttttctctaa taaaacaaaa gaggtgaaaa ccatagcaaa
    14581 gcaagactta ttcatcaatg atgagattcg tgtacgtgaa gttcgcttga ttggtcttga
    14641 aggagaacag ctaggtatca agccactcag tgaagcgcaa gctttggctg ataacgctaa
    14701 tgttgaccta gtattgattc aaccccaagc caaaccgcct gttgcaaaaa ttatggacta
    14761 cggtaagttc aaatttgagt accagaagaa gcaaaaagaa caacgtaaaa aacaaagcgt
    14821 tgttactgtg aaagaagttc gtctaagtcc aactattgac aagggtgact ttgatacaaa
    14881 acttcgtaat gcacgtaagt tccttgaaaa aggaaataaa gttaaggtat ctattcgctt
    14941 taagggtcgt atgattaccc ataaagagat tggtgcaaaa gttttagccg agtttgctga
    15001 agcaactcaa gatattgcca tcatcgaaca acgtgctaaa atggatggac gtcaaatgtt
    15061 catgcaattg gcgccagcga ctgacaaaaa ataattgtca gaaagttaaa taaaggagaa
    15121 aaaatcatgc caaaacaaaa aacacaccgc gcatcagcta aacgtttcaa acgtacaggt
    15181 tctggtggac ttaaacgttt ccgtgcttac acttctcacc gtttccacgg aaaaactaag
    15241 aaacaacgtc gtcatcttcg taaagcatct atggtgcatt caggagatta caaacgtatc
    15301 aaagcaatgc ttactcgctt gaaataatag cttgactgta agtaaacaat tctaggaaat
    15361 atttggagga aataaaacat ggcacgtgtt aaaggtggcg ttgtatcacg caaacgtcgt
    15421 aaacgtattc ttaaattagc aaaaggttac tatggagcta aacacatctt gttccgtact
    15481 gcaaaagaac aagtaatgaa ctcttactac tatgcatacc gtgaccgtcg tcagaaaaaa
    15541 cgtgacttcc gcaaattgtg gattactcgt atcaatgcgg cagctcgtat gaacggactt
    15601 tcatactcac aattgatgca tggtttgaaa ttggctgaga ttgaagttaa ccgtaaaatg
    15661 cttgctgact tggctgttaa cgatgcagta gctttcacag ctcttgcaga tgcagctaaa
    15721 gcaaaacttg gtaaataaca actgatgaga ctggaacagg attgtccagt ctttttaaaa
    15781 ataaaggaga aagatatggc ttcaaaaatg ctacacactt gcttacgagt agaaaatctt
    15841 gaaaaatcaa tcgcatttta tcaagatgct tttggtttta aagaattgcg tcgcagagat
    15901 tttccagacc atgccttcac gattgtctat ctaggtcttg agggtgatga ttatgagttg
    15961 gagttgactt ataactacga tcacggtccg tatgtggttg gtgatgggtt tgcccatatc
    16021 gccctcagta cacctgatct tgaggcactt catcaagaac acagtgcaaa aggctatgaa
    16081 gtgactgagc caaatggtct accaggaact acaccaaact attactttgt taaagaccct
    16141 gatggatata aggtcgaagt cattcgtgaa aaataatttc gtgcaagtta agtagaatat
    16201 tcgttttcta cttgactttt tttagctgaa agagtatact aataaaaatt caacctttaa
    16261 ggggagtcca gagagactca caaggtgtca gataaaagaa tagtgcaatt ttctagagga
    16321 gaccttttga gtgtgctctc ttgtgttgta cgattttaac tgaggccttg cactagcaag
    16381 gtcttttctt tatctggtcc ccttaaaatt taaggaggaa aagttatgaa tctcacatgt
    16441 aagaagcgtt tgggtgtcat tcggttggaa accatgaagg tggttgcaca agaggaaatc
    16501 gcgccagcaa tctttgaatt agtcctagaa ggagaaatgg ttgaagccat gcgagcaggc
    16561 caatttcttc atctgcgtgt accagacgat gcccatctct tacgtcgtcc tatttcaatt
    16621 tcgtctattg acaaggcaaa caagcagtgt cacctcattt atcggattga gggagctggg
    16681 actgcaattt tttcaacctt aagtcaggga gacactcttg atgtgatggg gcctcaggga
    16741 aatggttttg acttgtctga ccttgatgag cagaatcagg ttctccttgt tggtggtggg
    16801 attggtgttc cacccttgct tgaggtggcc aaggaattgc atgaacgtgg agtgaaagta
    16861 gtgacagtcc tcggttttgc taataaggat gctgttattt tgaaaacgga attggctcag
    16921 tatggtcagg tctttgtaac gacagatgat ggttcttatg gcatcaaggg aaatgtttcc
    16981 gttgttatca atgatttaga tagtcagttt gatgctgttt actcgtgtgg ggctccagga
    17041 atgatgaagt atatcaatca aacctttgat gatcacccaa gagcctattt atctctggaa
    17101 tctcgtatgg cttgtgggat gggagcttgc tatgcctgtg ttctaaaagt accagaaagc
    17161 gagacggtca gccaacgcgt ctgtgaagat ggtcctgttt tccgcacagg aacagttgta
    17221 ttataaggag aaaattatga ctacaaatcg attacaagtg tctctacctg gtttggattt
    17281 gaaaaatccg attattccag catcaggctg ttttggcttt ggacaagagt atgccaagta
    17341 ctatgattta gaccttttag gttctattat gatcaaggcg acaacccttg aaccacgttt
    17401 tgggaatcca actccaagag tggcagagac gcctgctggt atgctcaatg caattggctt
    17461 gcaaaatcct ggtttagagg ttgttttggc tgaaaagcta ccttggctgg aaagagaata
    17521 tccaaatctt cctattattg ccaatgtagc tggtttttca aaacaagagt atgcagctgt
    17581 ttctcatggg atttccaagg caactaatgt aaaagctatc gagctcaata tttcttgtcc
    17641 caatgttgac cactgtaatc atggactttt gattggtcaa gatccagatt tggcttatga
    17701 tgtggtgaaa gcagctgtgg aagcctcaga agtgccagtt tatgtcaaat taaccccgag
    17761 tgtgaccgat atcgttactg tcgcaaaagc tgcagaagat gcgggagcaa gtggcttgac
    17821 tatgatcaat actctggttg gaatgcgctt tgacctcaaa accagaaaac caatcttggc
    17881 caatggaaca ggtggaatgt caggtccagc agtctttcca gtagccctca aactcatccg
    17941 ccaagtagcc caaacaacag acctgcctat cattggaatg gggggagtgg attcggctga
    18001 agctgcccta gaaatgtatc tggctggggc atctgctatc ggagttggaa cagctaactt
    18061 taccaatcct tatgcctgcc ctgacatcat cgaaaattta ccaaaagtca tggataaata
    18121 cggtattagc agtctggaag aactccgtca ggaagtaaaa gagtctctga ggtaaactgc
    18181 aatcaatctg ttcttgattt tttattagtt tgtaatatga atttaggaga attttggtac
    18241 aataaaataa ataagaacag aggaagaagg ttaatgaaga aagtaagatt tattttttta
    18301 gctctgctat ttttcttagc tagtccagag ggtgcaatgg ctagtgatgg tacttggcaa
    18361 ggaaaacagt atctgaaaga agatggcagt caagcagcga atgagtgggt ttttgatact
    18421 cattatcaat cttggttcta tataaaagca gatgctaact atgctgaaaa tgaatggcta
    18481 aagcaaggtg acgactattt ttacctcaaa tctggtggct atatggccaa atcagaatgg
    18541 gtagaagaca agggagcctt ttattatctt gaccaagatg gaaagatgaa acgaaatgct
    18601 tgggtaggaa cttcctatgt tggtgcaaca ggtgccaaag taatagaaga ctgggtctat
    18661 gattctcaat acgatgcttg gttttatatc aaagcagatg gacagcacgc agagaaagaa
    18721 tggctccaaa ttaaagggaa ggactattat ttcaaatccg gtggttatct actgacaagt
    18781 cagtggatta atcaagctta tgtgaatgct agtggtgcca aagtacagca aggttggctt
    18841 tttgacaaac aataccaatc ttggttttac ataaaagaaa atggaaacta tgctgataaa
    18901 gaatggattt tcgagaatgg tcactattat tatctaaaat ccggtggcta catggcagcc
    18961 aatgaatgga tttgggataa ggaatcttgg ttttacctca agtttgatgg caaaatggct
    19021 gaaaaagaat gggtctacga ttctcatagt caagcctggt actacttcaa atccggtggt
    19081 tacatgacag ccaatgaatg gatttgggat aaggaatctt ggttttatct caaatctgat
    19141 gggaaaatag ctgaaaaaga atgggtctac gattctcata gtcaagcttg gtactacttc
    19201 aaatccggtg gttacatgac agccaatgaa tggatttggg ataaggaatc ttggttttac
    19261 ctcaagtctg atggcaaaat ggctgaaaaa gaatgggtct acgattctca tagtcaagcc
    19321 tggtactact tcaaatctgg tggctacatg gcgaaaaatg agacagtaga tggttatcag
    19381 cttggaagcg atggtaaatg gcttggagga aaagctacaa ataaaaatgc tgcttactat
    19441 caagtagtgc ctgtcacagc caatgtttat gattcagatg gtgaaaagct ttcctatata
    19501 tcgcaaggta gtgtcgtatg gctagataag gatagaaaaa gtgatgacaa gcgcttggct
    19561 attactattt ctggtttgtc aggctatatg aaaacagaag atttacaagc gctagatgct
    19621 agtaaggact ttatccctta ttatgagagt gatggccacc gtttttatca ctatgtggct
    19681 cagaatgcta gtatcccagt agcttctcat ctttctgata tggaagtagg caagaaatat
    19741 tattcggcag atggcctgca ttttgatggt tttaagcttg agaatccctt ccttttcaaa
    19801 gatttaacag aggctacaaa ctacagtgct gaagaattgg ataaggtatt tagtttgcta
    19861 aacattaata atagcctttt ggagaacaag ggcgctactt ttaaggaagc cgaagaacat
    19921 tatcatatca atgcccttta tctccttgcc catagtgccc tagaaagtaa ctggggaaga
    19981 agtaaaattg ccaaagataa gaataatttc tttggcatta cagcctatga tacgacccct
    20041 tacctttctg ccaagacatt tgatgatgtg gataagggaa ttttaggtgc aaccaagtgg
    20101 attaaggaaa attatatcga taggggaaga actttccttg gaaacaaggc ttctggtatg
    20161 aatgtggaat atgcttcaga cccttattgg ggcgaaaaaa ttgctagtgt gatgatgaaa
    20221 atcaatgaga agctaggtgg caaagattag tactataagt gaatatgatt tgagtgaata
    20281 gtaagttaaa aatcctgatt tcaagtaaaa tcaggatttt ttcatggatg caattttttt
    20341 ggagtctggt gtgacgcgga gggtcttttg tcctgtgtaa gtgacaaagc cgggttttcc
    20401 accagttggt ttattgagtt ttttgacttc aatcatatct acctgcacca gattcgacag
    20461 gcgcccttga gagaagtagg cagctaactc tgctgcgtct gtcttgactg catcagatgg
    20521 gtcaagattt cctgagatga caacatggct tccaggaatg tccttagcat ggaaccaaag
    20581 ttcctccttg cgggccattt taaaggtcaa ttcctcattt tgaagattgt ttcgtccgac
    20641 atagatgatg gttttgccat cgcttgctag atattgttct agttttttgc gtttctggat
    20701 tttctcccgt tgtcttctgc ggataaaacc tgtttgaatc aattcttcac ggatttcagc
    20761 gatttcttcc agtccagctt ggttgaggac ggtttctaca ctttccagat agagaatagt
    20821 ggctttggtt tcttcaatca aatcagtcaa gtatttgaca gcttctttga gtttctgata
    20881 ccgtttaaaa tagcgttggg cattctggtt gggagtcaga gccttatcaa gcgcaatcat
    20941 gataggttgg ttggtatagt agttgtctag gataacctgg tcttggtcgt taggcacttg
    21001 gtgtaggaag gttgtcagca attctccttt ttgacgaaat tcttcagcgt tgtctgtcgc
    21061 cagtaactct ttttcctgtt ttttgagttt gtgtcggttt ttctgaagtt cattttcaac
    21121 acgacgaatc agttcactgg cctgctgttt gacgcggtcg cgctcagcct tatccttata
    21181 gtaggtgtcc aacaaatcag aaagatttgc aaaaggctct cccacctgat ttgcaaaagg
    21241 aactggactg aaggaagtct cagtcaagca tggcttggtt tcttgattga aaaaatttcg
    21301 gaaagcggaa agtttttcac taaccagtat cctttccaat tcatttgcag tatcgcgtcc
    21361 cagaccttga aagaggcttt gaagattttt tgctgttagt tcttgggttt gcaggatttc
    21421 aaagagcttt tcatctttga tagtaaaagg attgagagat tctgtacttg gcggagcgat
    21481 ataggtcgat cctggaagta aggtgcggta gctattttgt gaaaaaccga cgtgtttgat
    21541 aacttcgagg attttatgac tgcttttatc gaccagtaga atattactgt gtttccccat
    21601 aatttcaata atcaaggtag cctggatatg gtctccaatc tcgtttttat tggaaactgt
    21661 aatttccaca atacggtcat tttccacttg ctcaatcgac tcaatcaggg ccccctgcaa
    21721 atactttctc aaaaccatga taaaggtaga aggttgagct ggattttcaa aagtcgtttg
    21781 ggtcagctga atgcgtccaa aaactggatg ggcagaaagg agcaggcgat ggctttggcg
    21841 attgctgcgg atttgcaaga ccaactcttg ttcaaaaggc tgattgattt tctggatgcg
    21901 accattcact aattcgcttc gcaattcctc aactatgtgg tgtaaaaaaa atccgtcaaa
    21961 tgacatcgtt ctctccttgt gattgtattc catagtatta tatcaaaaag gtagaataaa
    22021 atcatggaaa tgtggtataa taaagccaag taaagagaaa cgagaagcac atgtatattg
    22081 aaatggtaga tgaaactggt caagtttcaa aagaaatgtt gcaacaaacc caagaaattt
    22141 tggaatttgc agcccaaaaa ttaggaaaag aagacaagga gatggcagtc acttttgtga
    22201 ccaatgagcg tagtcatgaa cttaatctgg agtaccgtga caccgaccgt ccgacagatg
    22261 tcatcagcct tgagtataaa ccagaattgg aaattgcctt tgacgaagag gatttgcttg
    22321 aaaatccaga attggcagag atgatgtctg agtttgatgc ctatattggg gaattgttca
    22381 tctctatcga taaggctcat gagcaggccg aagaatatgg tcacagcttt gagcgtgaga
    22441 tgggcttctt ggcagtacac ggctttttac atattaacgg ctatgatcac tatactccgg
    22501 aagaagaagc ggagatgttc ggtttacaag aagaaatttt gacagcctat ggactcacaa
    22561 gacaataaac gaaaatggaa aaatcgtgac ttgatatcca gtttagaatt tgccatcaca
    22621 gggattttta ctgctatcaa ggaagaacga aatatgcgaa aacatgcagt gacggctcta
    22681 gtggtcatcc ttgcaggttt tgtttttcag gtgtcacgaa tcgaatggct ctttcttcta
    22741 ttgagtattt tcttggtagt agcctttgag attatcaact ctgctattga aaatgtggtg
    22801 gatttggcca gtcactatca cttttccatg ctggctaaaa atgccaagga tatggcggcc
    22861 ggcgcggtat tagtggtttc tctttttgca gccttaacag gcgcattgat ttttctccca
    22921 cgaatctggg atttattatt ttaaacagta agaggaaatt atgactttta aatcaggctt
    22981 tgtagccatt ttaggacgtc ccaatgttgg gaagtcaacc tttttaaatc acgttatggg
    23041 gcaaaagatt gccatcatga gtgacaaggc gcagacaacg cgcaataaaa tcatgggaat
    23101 ttacacgact gataaggagc aaattgtctt tatcgacaca ccagggattc acaaacctaa
    23161 aacagctctc ggagatttca tggttgagtc tgcctacagt acccttcgcg aagtggatac
    23221 cgttcttttc atggtgcctg ctgatgaagc gcgtggtaag ggggacgata tgattatcga
    23281 gcgtctcaag gctgccaagg ttcctgtgat tttggtggtg aataaaatcg ataaggtcca
    23341 tccagaccag ctcttgtctc agattgatga cttccgtaat caaatggact ttaaggaaat
    23401 tgttccaatc tcagcccttc agggaaataa cgtgtctcgt ctagtggata ttttgagtga
    23461 aaatctggat gaaggtttcc aatatttccc gtctgatcaa atcacagatc atccagaacg
    23521 tttcttagtt tcagaaatgg ttcgcgagaa agtcttgcac ctaactcgtg aagagattcc
    23581 gcattctgta gcagtagttg ttgactctat gaaacgagac gaagagacag acaaggttca
    23641 catccgtgca accatcatgg tcgagcgcga tagccaaaaa gggattatca tcggtaaagg
    23701 tggcgctatg cttaagaaaa tcggtagtat ggcccgtcgt gatatcgaac tcatgctagg
    23761 agacaaggtc ttcctagaaa cctgggtcaa ggtcaagaaa aactggcgcg ataaaaagct
    23821 agatttggct gactttggct ataatgaaag agaatactaa gtagaggtag gctcatgcct
    23881 gcttcttgtt tttacagaag gaggacttat gcctgaatta cctgaggttg aaaccgtttg
    23941 tcgtggctta gaaaaattga ttataggaaa gaagatttcg agtatagaaa ttcgctaccc
    24001 caagatgatt aagacggatt tggaagagtt tcaaagggaa ttgcctagtc agattatcga
    24061 gtcaatggga cgtcgtggaa aatatttgct tttttatctg acagacaagg tcttgatttc
    24121 ccatttgcgg atggagggca agtattttta ctatccagac caaggacctg aacgcaagca
    24181 tgcccatgtt ttctttcatt ttgaagatgg tggcacgctt gtttatgagg atgttcgcaa
    24241 gtttggaacc atggaactct tggtgcctga ccttttagac gcctacttta tttctaaaaa
    24301 attaggtcct gaaccaagcg aacaagactt tgatttacag gtctttcaat ctgcccttgc
    24361 caagtccaaa aagcctatca aatcccatct cctagaccag accttggtag ctggacttgg
    24421 caatatttat gtggatgagg ttctctggcg agctcaggtt catccagcta gatcttccca
    24481 gactttgaca gcagaagaag cgacagctat tcatgaccaa accattgctg ttttgagcca
    24541 ggctgttgaa aaaggcggtt ccaccattcg gacttatacc aatgcctttg gggaagatgg
    24601 aagcatgcag gactttcatc aggtctatga taagactggt caagagtgtg tacgctgtgg
    24661 taccatcatt gagaaaattc aactaggcgg acgaggcacc cacttttgtc caaactgtca
    24721 aaggagggac tgatgagaaa aatcatcgga atcactgggg gaattgcctc tggtaagtca
    24781 actgtgacaa attttctaag acagcaaggc tttcaagtag tggatgccga cgcagtcgtc
    24841 caccaactac agaaacctgg tggtcgtctg tttgaggctc tagtacagca ctttgagcaa
    24901 gaaatcattc ttgaaaacgg agaactcaat cgccctctcc tagctagtct catcttttca
    24961 aatcctgaag agcaaaaatg gtcgaagcaa attcaagggg agattatccg tgaggaactg
    25021 gctactttga gagaacagtt ggctcagaca gaagagattt tcttcatgga tattccccta
    25081 ctttttgagc aggactacag cgattggttt gctgagactt ggttggtcta tgtggaccga
    25141 gatgcccaag tagaacgctt aatgaaaagg gaccagttgt ccaaagatga agctgagtct
    25201 cgtctggcag cccagtggcc tttagaaaaa aagaaagatt tggccagcca ggttcttgat
    25261 aataatggca atcagaacca gcttcttaat caagtgcata tccttcttga gggaggtagg
    25321 caagatgaca gagattaact ggaaggataa tctgcgtatt gcctggtttg gtaattttct
    25381 gacaggagcc agtatttctt tggttgtacc ttttatgccc atcttcgtgg aaaatctagg
    25441 tgtagggagt cagcaagtcg ctttttatgc aggcttagca atttctgtct ctgctatttc
    25501 cgcggcgctc ttttctccta tttggggtat tcttgctgac aaatacggcc gaaaacccat
    25561 gatgattcgg gcaggtcttg ctatgactat cactatggga ggcttggcct ttgtcccaaa
    25621 tatctattgg ttaatctttc ttcgtttact aaacggtgta tttgcaggtt ttgttcctaa
    25681 tgcaacggca ctgatagcca gtcaggttcc aaaggagaaa tcaggctctg ccttaggtac
    25741 tttgtctaca ggcgtagttg caggtactct aactggtccc tttattggtg gctttatcgc
    25801 agaattattt ggcattcgta cagttttctt actggttggt agttttctat ttttagctgc
    25861 tattttgact atttgcttta tcaaggaaga ttttcaacca gtagccaagg aaaaggctat
    25921 tccaacaaag gaattattta cctcggttaa atatccctat cttttgctca atctcttttt
    25981 aaccagtttt gtcatacaat tttcagccca atcgatcggc cctattttgg ctctttatgt
    26041 acgcgactta gggcagacag agaatcttct ttttgtctct ggtttgattg tgtccagtat
    26101 gggcttttcc agcatgatga gtgcaggagt catgggcaag ctaggtgaca aggtgggcaa
    26161 tcatcgtctc ttggttgtcg cccagtttta ttcagtcatc atctatctcc tctgtgccaa
    26221 tgcctctagc ccccttcaac taggactcta tcgtttcctc tttggattgg gaaccggtgc
    26281 cttgattccc ggggttaatg ccctactcag caaaatgact cccaaagccg gcatttcgag
    26341 ggtctttgcc ttcaatcagg tattctttta tctgggaggt gttgttggtc ccatggcagg
    26401 ttctgcagta gcaggtcaat ttggctacca tgctgtcttt tatgcgacga gcctttgtgt
    26461 tgcctttagt tgtctcttta acctgattca atttcgaaca ttattaaaag taaaggaaat
    26521 ctagtgcgag taaaaatcaa tctcaaatgc tcctcttgtg gcagtatcaa ttacctaacc
    26581 agtaaaaatt caaaaaccca tccagacaag attgaggttt taaagtattg tcccaaggaa
    26641 aaaaaagtaa ccctacatct tgaatctaag tagattttat ggtaaaataa tagggatttt
    26701 aaggagtttg atatgtataa cctattatta accattttat tagtattatc tgttgtgatt
    26761 gtgattgcaa ttttcatgca accaaccaaa aaccaatcca gcaatgtatt tgatgccagt
    26821 tcaggtgatt tgtttgaacg cagtaaagct cgcggttttg aagctgtaat gcagcgtttg
    26881 acagggattt tagtcttttt ctggctagcc attgccttag cattgacggt attatcaagt
    26941 agataagaaa ataatgggca ggactaggtc tttgcctctt tttattttta aaggatgttt
    27001 gagaaggttt tacagtaaaa gaaaattaaa aaatctagaa agaaaatatg aaagatagaa
    27061 taaaagaata tttacaagac aagggaaagg tgactgttaa tgatttggct caggctttgg
    27121 gaaaagacag ttccaaggat tttcgtgagt tgattaaaac cttgtcctta atggaaagaa
    27181 agcaccaaat tcgttttgaa gaagatggta gtctgacatt agaaattaag aaaaaacatg
    27241 agattaccct caaggggatt tttcatgccc ataaaaatgg ctttggcttt gttagtctgg
    27301 aaggcgagga ggacgacctt tttgtaggga aaaatgatgt caactatgct attgatggtg
    27361 ataccgtcga ggtagtgatt aagaaagtcg ctgaccgcaa taagggaaca gcagcagaag
    27421 ccaaaattat tgatatccta gaacacagtt tgacaacagt tgtcgggcaa atcgttctgg
    27481 atcaggaaaa acctaagtat gctggctata ttcgttcaaa aaatcagaaa atcagtcaac
    27541 cgatttatgt taagaaacca gccctaaaat tagaaggaac agaagttctc aaggtcttta
    27601 tcgataaata cccaagcaag aaacatgatt tctttgtcgc gagtgttctc gatgtggtgg
    27661 gacactcaac ggatgtcgga attgatgttc ttgaggtttt ggaatcaatg gacattgtat
    27721 ccgagtttcc agaagctgtt gttaaggaag cagaaagtgt gcctgatgct ccgtctcaaa
    27781 aggatatgga aggtcgtctg gatctaagag atgaaattac ctttaccatt gacggtgcgg
    27841 atgccaagga cttggacgat gcagtgcata tcaaggctct gaaaaatggc aatctggagc
    27901 ttggggttca catcgcagat gtttcttatt atgtgaccga ggggtctgcc cttgacaagg
    27961 aagcccttaa ccgtgcgact tctgtttacg tgacagaccg agtggtgcca atgcttccag
    28021 aacgactatc aaatggcatc tgctctctca atccccaagt tgaccgcctg acccagtctg
    28081 ctattatgga gattgataaa catggtcgtg tggtcaacta taccattaca caaacagtta
    28141 tcaagaccag ttttcgtatg acctatagcg atgtcaatga tatcctagct ggcgatgaag
    28201 aaaagagaaa agaatatcat aaaattgtac caagtatcga actcatggcc aagcttcatg
    28261 aaactttaga aaacatgcgt gtgaaacgtg gagctctcaa ttttgatacc aatgaagcga
    28321 agattttagt ggataaacaa ggtaagcctg ttgatatcgt tcttcggcag cgtggcattg
    28381 ccgagcggat gattgagtct tttatgttga tggctaatga aacagttgcc gaacatttca
    28441 gcaagttgga tttgcctttt atctatcgaa ttcacgagga gcctaaggct gaaaaggttc
    28501 agaagtttat tgattatgct tcgagttttg gcttgcgcat ttatggaact gccagtgaga
    28561 ttagtcagga ggcacttcaa gacatcatgc gtgctgttga gggagaacct tatgcagatg
    28621 tattgtccat gatgcttctt cgctctatgc agcaggctcg ttattcggag cacaatcacg
    28681 gccactatgg actagctgct gactattata ctcactttac cagtccaatt cgtcgttatc
    28741 cagaccttct tgttcaccgt atgattcggg attacggccg ttctaaggaa atagtagagc
    28801 attttgagca agtgattcca gagattgcga cccagtcttc caaccgtgaa cgtcgtgcca
    28861 tagaagctga gcgtgaagtc gaagccatga aaaaggctga gtatatggaa gaatacgtgg
    28921 gtgaagagta tgatgcagtt gtatcaagta ttgtcaaatt cggtctcttt gtcgaattgc
    28981 caaacacagt tgaaggcttg attcacatca ctaatctacc tgaattttat catttcaatg
    29041 agcgtgattt gactcttcgt ggagaaaaat caggtatcac tttccgagtg ggtcagcaga
    29101 tccgtatccg tgttgaaaga gcggataaaa tgactggaga gattgatttt tcattcgtac
    29161 ctagtgagtt tgatgtgatt gaaaaaggct tgaaacagtc tagtcgtagt ggcatagggc
    29221 gtggttccaa tcgtcgttcg gataagaagg aagacaagag aaaatcagga cgctcaaatg
    29281 ataagcgtaa gtattcacaa aaagacaaga agaaaaaagg aaagaaacct ttttacaagg
    29341 aagtagctaa gaaaggagcc aagcatggca aagggcgagg gaaaggtcgt cgcacaaaat
    29401 aaaaaggcac gccacgacta tacaatcgta gatacgctag aggcagggat ggtcctgact
    29461 ggaactgaaa tcaagagtgt acgagctgct cgaattaatc tcaaggatgg ctttgctcaa
    29521 gtgaaaaatg gagaagtttg gctgagcaat gttcatatcg cgccttacga agagggcaat
    29581 atctggaacc aggaaccaga acgtcgtcgt aaactcctgc tccataaaaa gcaaattcaa
    29641 aaattggaac aagagaccaa agggacagga atgaccttag ttccccttaa ggtctatata
    29701 aaagatggct acgctaagct tcttttagga cttgccaaag ggaagcatga ctatgacaaa
    29761 cgggagtcta tcaaacgtcg tgagcaaaat cgagatatcg cgcgtgtgat gaaagctgtt
    29821 aatcagcgat aaaaagagga attgaaaatg gaaaaattag ttgcctataa acgcatgcct
    29881 ttgtggaata aacaaacaat gcctgaagct gttcagcaaa agcacaatac aaaagttggg
    29941 acttggggga aaattactgt cttgaaggga gctctcaagt ttattgaatt gacagaagaa
    30001 ggggaagttc tagctgaaca cctctttgaa gcaggggcag acaatccaat ggcccaacct
    30061 caagcctggc accgagtgga agctgccaca gatgatgtgg aatggtactt ggaattttat
    30121 tgtaaacctg aggattattt tgctaaaaaa tacaatacca atcctgttca ttcagaggtc
    30181 ctagaggcca tgcagacagt gaaacaaggg aaagctttgg atttgggttg tggtcagggg
    30241 cgtaattctc tttttctagc ccagcaagat tttgatgtga cggctgtaga tcaaaatgga
    30301 ctagctcttg aaatcttgca aagcattgtg gagcaggaag atttggacat gcctgttggc
    30361 ctttacgata tcaattcagc tagcattgaa caagaatatg attttatcgt ttcaacagtt
    30421 gttctcatgt ttctacaagc ggaccgcatt ccagctatta ttcaaaatat gcaggagaaa
    30481 accagtgttg gtggttacaa ccttatcgtt tgtgccatgg acacggagga ttatccttgc
    30541 tcggttaact tcccattcac ctttaaagaa ggagaactgg cagactatta caaggattgg
    30601 gaattggtta agtacaatga aaatccaggc catttgcacc gtcgcgatga gaatggcaat
    30661 cgtattcaac tacgctttgc gaccttacta gctaagaaaa tcaagtaaac atacatgaag
    30721 attaggaatt ttcctgatct tttttctttt ttacgaatga tatagaaaag gagggaattc
    30781 atgtttgttg cgagagatgc taggggagaa ttggtaaatg tgttagagga taaacttgag
    30841 aagcaagcat acacctgccc agcttgtgga ggccagatcc atttgcgtca aggaccaagt
    30901 gtacggacgc attttgccca taaatcctta aaagactgtg attttttctt tgaaaatgaa
    30961 agtccagaac acctggccaa taaggaatcc ctctatcact ggttgaaaaa agagacaaag
    31021 gttcaattag agtacccgct ttcagaactt aaacagattg cggatgtatt tgtaaatggc
    31081 aatctagctc tagaagttca gtgtagtccc ttgcctcaga aagtccttaa agagcgaagt
    31141 gagggctatc gtagtcaggg ttaccaagta ctgtggttgc tgggtcaaaa actgtggctc
    31201 aaggagcgtt tgactcgtct acagcaaggt tttctttatt tcagtcaaaa catgggcttt
    31261 tatgtttggg aattagacaa ggaaaaacaa gttttaagac tcaaatacct gatttaccag
    31321 gatctccgcg gtaaactcca ttatcaaatc aaggaatttt cctatggtca aggtagttta
    31381 ttggaaatat tgcgtcttcc ctataagaga caaaaaatat ctcattttac agtttctgag
    31441 gacaaggaca tctgtcgcta tatccggcaa caactttatt atcaaaatct cttttggatg
    31501 aaagaacaag cagaagccta tcaaaaggga gaaaatatcc tgacttatgg actgaaagaa
    31561 tggtatccac aaattcgacc aatagtgggc aaatttttcc agattgaaca agacttgact
    31621 agctattatc agcactttta tacctattac caaaaaaatc ctcaaaatga ttggcaaaag
    31681 ctttatccac cagcctttta tcagcaatat ttcttgaaaa atatggtaga atagaaagga
    31741 tggaggaatc taatggtatt acaaagaaat gaaataaatg aaaaagatac atgggatcta
    31801 tcaacgatct acccaactga ccaggcttgg gaagaagcct taaaagattt aacagaacaa
    31861 ttggagacag tagcccagta tgaaggccat ctcttggata gtgcggataa cctactagaa
    31921 atcactgaat tttctcttga aatggaacgc cagatagaga agctttacgt ttatgctcat
    31981 atgaagaatg accaggatac acgtgaagct aagtatcaag agtactatgc caaggccatg
    32041 acactctaca gccagttaga ccaagccttt tcattctatg agcctgaatt tatggagatt
    32101 agcgaaaagc agtatgctga ctttttagaa gctcaaccaa agctgcaggt ttatcaacac
    32161 tattttgaca agctcttgca aggcaaggat cacgttcttt cacaacgtga agaagaatta
    32221 ttggctggag ctggagaaat ctttggttca gcaagtgaaa ccttcgctat cttggacaat
    32281 gcggatattg tgttccctta tgtcctagac gatgatggta aagaagttca gctatctcat
    32341 gggacttaca cacgtttgat ggagtctaaa aaacgtgagg ttcgccgtgg tgcctatcaa
    32401 gctctttatg cgacttacga acaattccaa cacacctatg ccaaaacctt gcaaaccaat
    32461 gttaaggtgc aaaattaccg tgctaaagtt cgtaactaca agagtgctcg tcatgcagcc
    32521 ctcgcagcga attttgttcc agaaagtgtt tatgacaatt tggtagcagc agttcgcaag
    32581 catttgccac tcttacatcg ctatcttgag cttcgttcaa aaatcttggg gatttcagat
    32641 ctcaagatgt acgatgtcta cacaccgctt tcatctgttg aatacagttt tacctaccaa
    32701 gaagccttga aaaaagcaga agatgctttg gcagtcttgg gtgaggatta cttgagccgt
    32761 gttaaacgtg ccttcagcga gcgttggatt gatgtttacg aaaatcaagg caagcgttca
    32821 ggtgcctact ctggtggttc ttacgatacc aatgccttta tgcttctcaa ctggcaggac
    32881 aatctggaca atctctttac tcttgttcat gaaacaggtc acagtatgca ttcaagctat
    32941 actcgtgaaa ctcagcctta tgtttacggg gattactcta tctttttggc tgagattgcc
    33001 tcaactacca atgaaaatat cttgacggag aaattattgg aagaagtgga agacgacgca
    33061 acacgctttg ctattctcaa taacttccta gatggtttcc gtggaacagt tttccgccaa
    33121 actcaatttg ctgagtttga acacgccatt caccaagcag atcaaaatgg ggaggtcttg
    33181 acaagcgatt tcctaaataa actctacgca gacttgaacc aagagtatta tggtttgagt
    33241 aaggaagaca atcctgaaat ccaatacgag tgggctcgca ttccacactt ctactataac
    33301 tactatgtat atcaatattc aactggcttt gcggccgcct cagccttggc tgaaaaaatt
    33361 gtccatggta gtcaagaaga ccgtgaccgc tatatcgact acctcaaggc aggtaagtcg
    33421 gactatccac ttaatgtcat gagaaaagct ggtgttgata tggagaagga agactacctc
    33481 aacgatgcct ttgcagtctt tgaacgccgt ttaaatgagt ttgaagccct tgttgaaaaa
    33541 ttaggattgg cataaaatgg ttgaatcgta tagtaagaat gctaaccata acatgcgtcg
    33601 tcctgtcgtc aaagaagaaa ttgtagactt gatgcgtcag cgtcaaaagc aggtcacagg
    33661 tttcttgaaa gaattggaag actttgcccg caaggaaaat attcctatta ttccccatga
    33721 aacggttgct tatttccgtt ttcttatgga aaccatgcag cctaaaaata ttctggaaat
    33781 tgggacggct atcggttttt cagctctctt gatggctgaa catgcgccaa atgctaagat
    33841 tacaactatt gatcgtaatc cagaaatgat tggttttgcc aaggaaaatt ttgcccagtt
    33901 tgacagtcgc aagcaaatca ctctcctaga gggagatgcg gtggatgtct tatctacact
    33961 gacagagtct tatgatttcg tatttatgga ttctgccaag tctaaataca tcgtctttct
    34021 gccagaaatc ctcaaacatt tggaagttgg tggtgtggtt gtcttggatg atatttttca
    34081 aggtggtgat gttgccaagg atattatgga agtccgtcgt ggtcagcgaa ccatttatcg
    34141 aggccttcaa aaattatttg atgcaacctt agacaatcca gaactcaccg caacattagt
    34201 gcctttagga gatggtattc tcatgcttcg taaaaatgta gcagatgttc aactgtctga
    34261 aagcgaatga ttttcagaaa aatttaagaa aaaatagtaa aatagataga gtaacactta
    34321 tctcaaagga gtagacatga agaaaaaatt attggcaggt gccatcacac tattatcagt
    34381 agcaacttta gcagcttgtt cgaaagggtc agaaggagca gaccttatca gcatgaaagg
    34441 ggatgtcatc acagaacatc aattttatga gcaagtgaaa aacaaccctt cagcccaaca
    34501 agtcttgtta aatatgacca tccaaaaagt ttttgaaaaa caatatggct cagagcttga
    34561 tgataaagag gttgatgata ctattgccga agaaaaaaaa caatatggcg aaaactacca
    34621 acgtgtcttg tcacaagcag gtatgactct tgaaacacgt aaagctcaaa ttcgtacaag
    34681 taaattagtt gagttggcag ttaagaaggt agcagaagct gaattgacag atgaagccta
    34741 taagaaagcc tttgatgagt acactccaga tgtaacggct caaatcatcc gtcttaataa
    34801 tgaagataag gccaaagaag ttctcgaaaa agccaaggca gaaggtgctg attttgctca
    34861 attagccaaa gataattcaa ctgatgaaaa aacaaaagaa aatggtggag aaattacctt
    34921 tgattctgct tcaacagaag tacctgagca agtcaaaaaa gccgctttcg ctttagatgt
    34981 ggatggtgtt tctgatgtga ttacagcaac tggcacacaa gcctacagta gccaatatta
    35041 cattgtaaaa ctcactaaga aaacagaaaa atcatctaat attgatgact acaaagaaaa
    35101 attaaaaact gttatcttga ctcaaaaaca aaatgattca acatttgttc aaagcattat
    35161 cggaaaagaa ttgcaagcag ccaatatcaa ggttaaggac caagccttcc aaaatatctt
    35221 tacccaatat atcggtggtg gagattcaag ctcaagcagt agtacatcaa acgaatagtc
    35281 caaatcaatg agtcagggaa aaaactctac ttcaggaaaa aatgaagcaa acattcccac
    35341 aataaaacgc gtagtacaag gtttgtactg acccccaaaa gttagacaaa taatttatcc
    35401 gaaggattta gttctgtatt gcacagggct aagtcctttt agttttacct taattctctt
    35461 gttgttgtaa taatcaatat agtctataat ggcttgttcc aattgattaa gtgatttaaa
    35521 tgttttctca tagccataaa acatttcgga ttttaaaata ccaaagaaag attccatcct
    35581 accgttgtct tggctgtttc ccttgcgtga catagatgct tgaattccct tactctctag
    35641 gaaccgatga taagaatcgt gttggtattg ccagtcttgg tcactatgga gaatcgtatt
    35701 ctcgtagtgc ttctctttga atgcctgttc caacattaac gatcaatcaa tttaatcatg
    35761 tacctaatat t
//
LOCUS       DAVLCS010000020        34715 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLCS010000020 DAVLCS010000000
VERSION     DAVLCS010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34715
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.020"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            777..1229
                     /locus_tag="VXC78_001116"
     CDS             777..1229
                     /locus_tag="VXC78_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0583209.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGEVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1248..2585
                     /locus_tag="VXC78_001117"
     CDS             1248..2585
                     /locus_tag="VXC78_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV0583210.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2664..3548
                     /locus_tag="VXC78_001118"
     CDS             2664..3548
                     /locus_tag="VXC78_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0583211.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3548..4381
                     /locus_tag="VXC78_001119"
     CDS             3548..4381
                     /locus_tag="VXC78_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0583212.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4400..6493
                     /gene="nanB"
                     /locus_tag="VXC78_001120"
     CDS             4400..6493
                     /gene="nanB"
                     /locus_tag="VXC78_001120"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV0583213.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6506..7609
                     /locus_tag="VXC78_001121"
     CDS             6506..7609
                     /locus_tag="VXC78_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0583214.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7783..8481
                     /locus_tag="VXC78_001122"
     CDS             7783..8481
                     /locus_tag="VXC78_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0583215.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8500..10017
                     /locus_tag="VXC78_001123"
     CDS             8500..10017
                     /locus_tag="VXC78_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0583216.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            10142..11470
                     /locus_tag="VXC78_001124"
     CDS             10142..11470
                     /locus_tag="VXC78_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0583217.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11722..12588
                     /locus_tag="VXC78_001125"
     CDS             11722..12588
                     /locus_tag="VXC78_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0583218.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12604..13443
                     /locus_tag="VXC78_001126"
     CDS             12604..13443
                     /locus_tag="VXC78_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0583219.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13715..14167
                     /locus_tag="VXC78_001127"
     CDS             13715..14167
                     /locus_tag="VXC78_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0583220.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14309..14617
                     /locus_tag="VXC78_001128"
     CDS             14309..14617
                     /locus_tag="VXC78_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583221.1"
                     /translation="MDGQGITVDEMAWIIRGIVNALIGRYIKLGTYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFANNIAAAWDAHDKIPNNGRINF
                     "
     gene            14627..14842
                     /locus_tag="VXC78_001129"
     CDS             14627..14842
                     /locus_tag="VXC78_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583222.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFDEHTWSTILIASLFGV
                     YDYKPIDKNRKSPKEKRKNRFVHGRDL"
     gene            14900..15544
                     /locus_tag="VXC78_001130"
     CDS             14900..15544
                     /locus_tag="VXC78_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0583223.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSAFLLFGFGLLAFLQVGVMEKLFAKYE"
     gene            15717..16634
                     /locus_tag="VXC78_001131"
     CDS             15717..16634
                     /locus_tag="VXC78_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV0583224.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEILKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVIEEDRPVVEAAAALIRETKERFL"
     gene            16652..17536
                     /locus_tag="VXC78_001132"
     CDS             16652..17536
                     /locus_tag="VXC78_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0583225.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17552..18403)
                     /locus_tag="VXC78_001133"
     CDS             complement(17552..18403)
                     /locus_tag="VXC78_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0583226.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18603..20660
                     /gene="pbp2b"
                     /locus_tag="VXC78_001134"
     CDS             18603..20660
                     /gene="pbp2b"
                     /locus_tag="VXC78_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV0583227.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKELP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20671..21267
                     /gene="recR"
                     /locus_tag="VXC78_001135"
     CDS             20671..21267
                     /gene="recR"
                     /locus_tag="VXC78_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV0583228.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21443..22486
                     /locus_tag="VXC78_001136"
     CDS             21443..22486
                     /locus_tag="VXC78_001136"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV0583229.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPGLIERLVDL
                     AKESFDKREAHLI"
     gene            22570..23943
                     /locus_tag="VXC78_001137"
     CDS             22570..23943
                     /locus_tag="VXC78_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV0583230.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDTVIFYGQDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            23930..24541
                     /locus_tag="VXC78_001138"
     CDS             23930..24541
                     /locus_tag="VXC78_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0583231.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            24632..25336
                     /locus_tag="VXC78_001139"
     CDS             24632..25336
                     /locus_tag="VXC78_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV0583232.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25555..26928
                     /gene="ftsA"
                     /locus_tag="VXC78_001140"
     CDS             25555..26928
                     /gene="ftsA"
                     /locus_tag="VXC78_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV0583233.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26945..28204
                     /gene="ftsZ"
                     /locus_tag="VXC78_001141"
     CDS             26945..28204
                     /gene="ftsZ"
                     /locus_tag="VXC78_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV0583234.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            28209..28880
                     /locus_tag="VXC78_001142"
     CDS             28209..28880
                     /locus_tag="VXC78_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV0583235.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28890..29429
                     /locus_tag="VXC78_001143"
     CDS             28890..29429
                     /locus_tag="VXC78_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV0583236.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29429..29692
                     /locus_tag="VXC78_001144"
     CDS             29429..29692
                     /locus_tag="VXC78_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV0583237.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29689..30474
                     /locus_tag="VXC78_001145"
     CDS             29689..30474
                     /locus_tag="VXC78_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV0583238.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEYL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30483..31271
                     /gene="divIVA"
                     /locus_tag="VXC78_001146"
     CDS             30483..31271
                     /gene="divIVA"
                     /locus_tag="VXC78_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV0583239.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31619..34411
                     /locus_tag="VXC78_001147"
     CDS             31619..34411
                     /locus_tag="VXC78_001147"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV0583240.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPVGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     ICFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10689 a         6108 c         7527 g        10391 t
ORIGIN      
        1 tcaatatatt atacgactat taaccttatc ttctcctaaa attgactttc ttgttttctt
       61 atcttgtcta ctcgaaacaa gtattgtaag aatttgatta tttttgaaag tacttttaat
      121 atacttgata tagttaaaaa agatttgaaa ctaaattcca aattagaaaa agacttgaaa
      181 tactaaaaaa aaaaagtata ctctaattga aaacggtaac aaaactaatt tagagaatga
      241 aatatagagt atttctctct taaaagtttt tggtgaaacg agatgtagaa aggagattta
      301 gccaaagagt ctattagtgc tagaataata gattagaatt attttagaaa aacgaagtga
      361 gcagcttata aattcaagtc cccaaataga ttcatactag tatcttttgc aaaaaataaa
      421 gggcgatttc cttcatgaat atcaatttca tctataagga aggtagctaa ttgaactaac
      481 ttatttattc tgtttgtcgc tagaaaaatc agacctcctt gtgaagattg aggagatact
      541 gaatgaaaat caaagaagaa actagcaagc tagtagcaga ttgcccaaaa caccgctttg
      601 aggttgtaga taagactgac gtatataatc caaggtgaag cgactgtggt ttgaagagat
      661 tttcaaagag tataggctag agagtagtgt ttttatgtcc ttctagtaga aaatgctaga
      721 cagaagaatg gggaacttgg ataggaaaaa tagattgaga aaggaggtta gaagagatga
      781 ttattacaaa aattagccgt ttaggaactt atgtgggagt aaatccacat tttgcaacat
      841 taatagattt tttagaaaaa acaggactag aaaatttaac agaaggttcg attgctatcg
      901 atggtaatcg attgtttggg aattgcttta cttatctagc agatggtcaa gcaggagcct
      961 tctttgaaac ccaccaaaaa tatttggata ttcatttagt gctggaaaac gaagaagcca
     1021 tggctgtgac gtcgccggaa aatgtaagcg ttacccaaga gtatgatgaa gagaaggata
     1081 ttgaattata cacaggggaa gtggaacagt tagttcattt gagagctggc gaatgcctca
     1141 tcacttttcc agaagattta catcaaccca aggttcgtat aaatgatgaa cctgtgaaaa
     1201 aagttgtctt taaagttgcg atttcttaat gtagaaagag aagaacgatg aaaaaaatga
     1261 gaaagttttt atgtctagct ggaattgcgc tagcggctgt tgccttggta gcttgttcag
     1321 gaaaaaaaga agctacaact agtactgaac caccaacaga attatctggt gagattacaa
     1381 tgtggcactc ctttactcaa ggaccccgtt tagaaagtat tcaaaaatca gcagatgctt
     1441 tcatgcaaaa gcatccaaaa acgaaaatca agattgaaac attttcttgg aatgacttct
     1501 atactaaatg gactacaggt ttagcaaatg gaaatgtgcc agatatcagt acagctcttc
     1561 ctaaccaagt aatggaaatg gtcaactcag atgctttggt tccgctaaat gattctatca
     1621 agcgtattgg acaagataaa tttaacgaaa ctgccttaaa tgaagcaaaa atcggagatg
     1681 attactactc tgttcctctt tattcacatg cacaagtcat gtgggttaga acagatttgt
     1741 taaaagaaca taatattgag gttcctaaaa cttgggatca actctatgaa gcttctaaaa
     1801 aattgaaaga agctggagtt tatggcttgt ctgttccgtt tggaacaaat gacttaatgg
     1861 caacacgttt cttgaacttc tacgtacgta gtggtggagg aagcctctta acaaaagatc
     1921 ttaaagcaga cttgacaagc caacttgctc aagatggtat taaatactgg gttaaattgt
     1981 ataaagaaat ctcacctcaa gattctttga actttaatgt ccttcaacaa gctaccttgt
     2041 tctatcaagg aaaaacagca tttgacttta actctggctt ccatatcgga ggaattaatg
     2101 ccaacagtcc tcaattgatt gattcgattg atgcttatcc tattccaaaa atcaaagagt
     2161 ctgataaaga ccaaggaatt gaaacctcaa acattccaat ggttgtttgg aaaaattcaa
     2221 aacatccaga agttgctaaa gcattcttag aagcacttta taatgaagaa gactacgtta
     2281 aattccttga ttcaactcca gtaggtatgt tgccaactat taaggggatt agcgattctg
     2341 cagcctataa agaaaatgaa actcgtaaga agtttaaaca tgctgaagaa gtaattactg
     2401 aagctgttaa aaaaggtact gctattggtt atgaaaatgg accaagtgta caagctggta
     2461 tgttgactaa ccaacacatt attgaacaaa tgttccaaga tatcattaca aatggaacag
     2521 atcctatgaa agcagcaaaa gaagcagaaa aacaattaaa tgatttattt gaggctgttc
     2581 agtagatgta aaagactaga aaataggtgg gctagtgagc tgaaaagctc tagcccaatc
     2641 ttgtaaaaga agggagaagg agaatggtta aagaacgtaa tttaactcgc tggatatttg
     2701 ttttgccagc tatgattatc gtaggattac tctttgttta tccgtttttc tcgagtattt
     2761 tttatagctt taccaataag catttgatta tgcctaatta taaatttgtt ggtttggcta
     2821 actataaagc tgtgctatca gatcccaact tctttaatgc gttctttaat tcaattaagt
     2881 ggaccgtttt ctcattagtt ggtcaagttt tagtagggtt tgtattggct ttagctcttc
     2941 acagagtacg ccacttcaag aaattatata ggaccttatt gattgttcct tgggcatttc
     3001 ctaccatcgt tattgccttt tcttggcagt ggattctaaa cggggtttat ggctacttac
     3061 ctaatctaat cgtaaaatta ggtttaatgg aacatacacc tgcatttttg acagatagta
     3121 catgggcatt cctatgtttg gtgtttatca acatttggtt tggagcacca atgattatgg
     3181 ttaatgtgct ttcagctttg caaacagtac cagaagaaca atttgaggct gctaagatag
     3241 atggtgcttc aagttggcag gtgttcaagt ttatcgtctt tccacatatt aaagtggttg
     3301 taggacttct agttgttttg agaactgtat ggatctttaa taactttgac attatctacc
     3361 tcattactgg tggtggacca gccaatgcta caacgacgct tccaattttt gcttacaacc
     3421 tgggttgggg aactaaattg ttgggtcgtg cttcagcagt tacagtattg ctctttatct
     3481 tcttggtggc gatttgcttt atctactttg ctatcatcag taagtgggaa aaggagggta
     3541 gaaaataatg aagaagaaat ccagtattta tttagatatt ctctcacatg tacttttagt
     3601 tggtgcgacc atcgttgcaa ttttcccatt ggtatggatt atcatatctt ctgtcaaagg
     3661 gaaaggggaa ttaactcagt atccaacacg attttggcct gaacagttta cattagatta
     3721 tttcactcat gttatcaacg atttgcactt cattgataac attcgaaaca gtttaatcat
     3781 tgccttggct acaaccctca ttgcgattat tatttctgct atggcagcct atggtattgt
     3841 tcgattcttt cctaaattgg gagcaatcat gtcgagacta ctcgtcatta cctatatttt
     3901 cccaccaatt ttgttagcaa ttccctattc aattgccatt gctaaagttg ggttaacaaa
     3961 tagtttattt ggcttgatga tggtttatct atcttttagt gttccatatg cagtttggct
     4021 cttagttgga tttttccaaa cagttccaat tggaattgaa gaagcggcta gaattgatgg
     4081 tgcaaataaa tttgttacgt tttataaagt tgtgctaccg attgtagcac caggtattgt
     4141 agcaacagct atttatacat ttatcaatgc ttggaatgaa ttcctgtatg ccttgatttt
     4201 gattaacaat acaggaaaga tgacagtagc agtagccctt cgttcactta atggttcaga
     4261 aatactagac tggggagata tgatggcagc gtctgttatt gtagttcttc catcaattat
     4321 tttcttctct atcatccaaa ataagattgc aagtggatta tcagaaggat ctgtgaagta
     4381 gacgaaagaa ggaaaaaaaa tgaataaaag aggtctttat tcaaaactag gaatttctgt
     4441 tgtaggcatt agtcttttaa tgggagttcc cactttgatt catgcgaatg aattaaacta
     4501 tggtcaactg tccatatctc ctatttttca aggaggttca tatcaactga acaataagag
     4561 tatagatatc agctctttgt tattagataa attgtctgga gagagtcaga cagtagtaat
     4621 gaaatttaaa gcagatgaac caaactctct tcaagctttg tttggcctat ctaatagtaa
     4681 agcaggcttt aaaaataatt acttttcaat tttcatgaga gattctggtg agataggtgt
     4741 agaaataaga gacgcccaaa agggaataaa ttatttattt tctagaccag cttcattatg
     4801 gggaaagcat aaaggacagg cagttgaaaa tacactagta tttgtatctg attctaaaga
     4861 taaaacatac acaatgtatg ttaatggaat agaagtgttc tctgaaacag ttgatacatt
     4921 tttgccaatt tcaaatataa atggtataga taaggcaaca ctaggagctg ttaatcgtga
     4981 aggtaaggaa cattacctcg caaaaggaag tattgatgaa atcagtctat ttaacaaagc
     5041 aattagtgat caggaagttt caaatattcc cttgtcaaat ccatttcagt taattttcca
     5101 atcaggagat tctactcaag ctaactattt tagaataccg acactatata cattaagtag
     5161 tggaagagtt ctatcaagta ttgatgcacg ttatggtggg actcatgatt ctaaaagtaa
     5221 gattaatatt gccacttctt atagtgatga taatgggaaa acgtggagtg agccaatttt
     5281 tgctatgaag tttaatgact atgaggagca gttagtttac tggccacgag ataataaatt
     5341 aaagaatagt caaattagtg gaagtgcttc attcatagat tcatccattg ttgaagataa
     5401 aaaatctggg aaaacgatat tactagctga tgttatgcct gcgggtattg gaaataataa
     5461 tgcaaataaa gccgactcag gttttaaaga aataaatggt cattattatt taaaactaaa
     5521 gaagaatgga gataacgatt tccgttatac agttagagaa aatggtgtcg tttatgatga
     5581 aacaactaat aaacctacaa attatactat aaatgataag tatgaagttt tggagggagg
     5641 aaagtcttta acagtcgaac aatattcggt tgattttgat agtggctctt taagagaaaa
     5701 acataatgga aaacaggtcc ctatgaatgt tttctacaaa gattcgttat ttaaagtgac
     5761 tcctactaat tatatagcaa tgacaactag tcagaataga ggagagagtt gggaacaatt
     5821 taagttgttg cctccgttct taggagaaaa acataatgga acttacttat gtcccggaca
     5881 aggtttagca ttaaaatcaa gtaacagatt gatttttgca acatatacta gtggagaact
     5941 aacctatctc atttctgatg atagtggtca aacatggaag aaatcctcag cttcaattcc
     6001 gtttaaaaat gcaacagcag aagcacaaat ggttgaactg agagatggtg tgattagaac
     6061 attctttaga accactacag gtaagatagc ttatatgact agtagagatt ctggagaaac
     6121 atggtcgaaa gtttcgtata ttgatggaat ccaacaaact tcatatggca cacaagtatc
     6181 tgcaattaaa tactctcaat taattgatgg aaaagaagca gtcattttga gtacaccaaa
     6241 ttctagaagt ggccgtaagg gaggtcaatt agttgttggt ttagtcaata aagaagatga
     6301 tagtattgat tggaaatacc actatgatat tgatttgcct tcgtatggtt atgcctattc
     6361 tgcgattaca gaattgccaa atcatcacat aggtgtgctg tttgaaaaat atgattcgtg
     6421 gtcgagaaat gaattgcatt taagcaatgt agttcagtat atagatttgg aaattaatga
     6481 tttaacaaaa taaaggagaa aaaacatggt taaatacggt gttgttggag cagggtattt
     6541 tggagctgaa ttggctcgct acatgcaaaa gaatgatgga gcagagatta ctcttctcta
     6601 tgatccagat aatgcagagg cgattgcaga agaattggga gcaaaagtag caagttcctt
     6661 agatgagttg gtttctagcg atgaagtaga ttgtgttatc gtcgcaactc caaataatct
     6721 tcataaggaa ccggttatta aggctgcaca gcatggtaaa aatgttttct gtgaaaaacc
     6781 aattgcgctt tcttatcaag attgtcgcga gatggtagat gcgtgtaaag aaaacaatgt
     6841 aacctttatg gcaggacata ttatgaattt ctttaatggt gttcatcatg caaaagaact
     6901 cattaatcaa ggagttatcg gagacgttct atattgtcat acagctcgta atggttggga
     6961 agaacaacaa ccgtcagtat catggaaaaa aattcgtgaa aaatcaggtg gtcacttgta
     7021 tcaccacatc catgaattgg attgcgttca attccttatg gggggcatgc ctgaaactgt
     7081 aaccatgaca ggtggaaatg tggcccatga aggtgaacat ttcggtgatg aagatgatat
     7141 gatttttgtc aatatggaat tttctaataa gcgttttgcc ttgttagaat ggggttcagc
     7201 ttatcgttgg ggtgaacatt atgtcttaat ccaaggaagc aaaggtgcca tccgcttaga
     7261 cttattcaac tgtaaaggaa ctcttaagct agatgggcaa gaaagctatt tcttgattca
     7321 cgaatcgcaa gaagaagatg atgatcggac tcgtatctat catagtacag agatggatgg
     7381 agcaattgct tatggtaaac caggtaaacg tactccatta tggctatcat ctgtcattga
     7441 taaagaaatg cgctatctgc atgagattat ggaaggagcc ccagtatcag aagaatttgc
     7501 aaaacttttg acaggtgaag ctgccctaga agcaattgct actgcagatg cttgtaccca
     7561 gtctatgttt gaagatcgca aagtaaaatt gtcagaaatt gtaaaataaa ttttggtatt
     7621 ctcctattta taggtcgact tgctcctctg aaagtacttt tagaggagct gtttgacttt
     7681 gctagttttt gaaactgaaa tctattatac tacaaactat tgaaagcgtt ttaattttaa
     7741 ggtataataa tctcatagaa ataaagaaaa ggaggaaaga ggatgccaca gattagcaaa
     7801 gaagccttga ttgagcaaat caaagatgga atcatcgttt cttgtcaggc tcttcctcat
     7861 gaaccgcttt atacagaagc gggaggggtg attcccttgc tggtcaaagc ggctgagcaa
     7921 ggtggagcag tcggtatccg agcaaacagt gttcgcgata tcaaggaaat taaggaagtc
     7981 actaaacttc caatcattgg gattatcaaa cgtgattatc cacctcagga acccttcatc
     8041 acggctacta tgaaagaagt tgatgaattg gcagaactgg acatcgaggt gattgctctg
     8101 gattgtacca agcgtgaacg ctacgatggt ttggaaattc aagagttcat tcgtcaggtt
     8161 aaggagaaat atcctaatca gcttttgatg gctgatacta gtatcttcga agaagggcta
     8221 gcagctgtag aagcaggaat tgactttgtc ggaacaacct tatcaggcta cacatcctac
     8281 agtccaaaag tagacggtcc agattttgaa ttgattaaga aactctgtga tgccggtgta
     8341 gatgtcattg cagaaggaaa aattcataca ccagaacaag ccaaacaaat ccttgaatat
     8401 ggagtgcgag gcatcgttgt tggtggcgcc attactagac caaaagagat tacagaacgc
     8461 ttcgttgcta gtcttaaata agatgtgaga gggagtttta tgtttaaagt tttacaaaaa
     8521 gttggaaaag cttttatgtt acctatagct atacttcctg cagcaggtct acttttgggg
     8581 attggtggtg cactttcaaa cccaaccacg atagcaactt atccaatact agacaatagt
     8641 atttttcaat caatattcca agtaatgagc tctgcaggag aggttgtatt cagtaatttg
     8701 tcactacttc tctgtgtggg attatgtatt ggcttagcga aacgagataa aggaaccgct
     8761 gcgttagcag gagtaactgg ttacttagtt atgactgcaa cgatcaaagc tttggtaaaa
     8821 ctttttatgg cagaaggatc tgcaattgat actggagtta ttggagcatt agttgtcgga
     8881 atagttgccg tatatttgca caaccgatat aacaatattc aattaccttc cgctttagga
     8941 ttctttggag gttcacgctt cgttcctatt gttacatcgt tctcttctat cttgattggc
     9001 tttgtcttct ttgttatttg gccacctttc caacaacttc ttgtttctac aggtggatat
     9061 atttctcagg cgggtccaat tggaactttt ctatatggat ttttaatgag actttctgga
     9121 gcagtaggct tacatcatat aatttaccct atgttttggt atactgaact tggtggtgtt
     9181 gaaactgttg caggacaaac agtggttgga gctcaaaaaa tattttttgc tcaattagcc
     9241 gatccggccc attctggatt atttacagaa ggaacaaggt tttttgcagg tcgtttctca
     9301 acaatgatgt tcggtttacc ggctgcctgt ttagcgatgt accatagtgt tcctaaaaat
     9361 cgtcgtaaaa aatacgcggg tttgtttttt ggagttgctt taacatcttt tattaccggt
     9421 attacagaac caattgaatt tatgtttcta ttcgtcagtc cggttctata tgttgttcac
     9481 gcattccttg atggtgttag cttctttatt gcagacgtct taaatatttc aataggaaac
     9541 acattttcag gaggtgtaat cgatttcact ttatttggaa ttttgcaggg gaacgctaag
     9601 acgaattggg ttcttcagat tccaattgga cttatttgga gtgttttgta ttatattatt
     9661 tttagatggt tcattactca attcaacgtt ctaacgccag gacgaggaga agaagtagat
     9721 tctaaagaaa tttctgaatc cgcagattca acttcaaata ctgcagatta tttaaaacag
     9781 gatagcctac aaattatcag agccttgggt ggatcaaata atatagaaga tgtagatgct
     9841 tgtgtgacac gtttacgtgt agctgtaaaa gaagttaatc aagttgataa agcactttta
     9901 aaacaaattg gtgcagttga tgtcttagaa gtgaagggtg gcattcaagc aatctatgga
     9961 gcaaaagcaa tcttatataa aaatagtatt aatgaaattt taggtgtaga tgattaagta
    10021 cttactgact taataaaaaa cagaggagag tgatggatga gtaggatgaa atgaaatcgt
    10081 atacaagaaa taaagaactc attatccaag ttggatacgc ttattacata ggagaataca
    10141 aatgaaattt agaaaattag cttgtacagt acttgcgggt gctgcggttc ttggtcttgc
    10201 tgcttgtggc aattctggcg gaagtaaaga tgctgccaaa tcaggtggtg acggtgccaa
    10261 aacagaaatc acttggtggg cattcccagt atttacccaa gaaaaaactg gtgacggtgt
    10321 tggaacttat gaaaaatcaa tcatcgaagc gtttgaaaaa gcaaacccag atataaaagt
    10381 gaaattggaa accatcgact tcaagtcagg tcctgaaaaa atcacaacag ccatcgaagc
    10441 aggaacagct ccagacgtac tctttgatgc accaggacgt atcatccaat acggtaaaaa
    10501 cggtaaattg gctgagttga acgacctctt cacagatgaa tttgttaaag atgtcaacaa
    10561 tgaaaacatc gtacaagcaa gtaaagctgg agacaaggct tatatgtatc cgattagttc
    10621 tgccccattc tacatggcaa tgaacaagaa aatgttagaa gatgctggag tagcaaacct
    10681 tgtaaaagaa ggttggacaa ctgatgattt tgaaaaagta ttgaaagcac ttaaagacaa
    10741 gggttacaca ccaggttcat tgttcagttc tggtcaaggg ggagaccaag gaacacgtgc
    10801 ctttatctct aacctttata gcggttctgt aacagatgaa aaagttagca aatatacaac
    10861 tgatgatcct aaattcgtca aaggtcttga aaaagcaact agctggatta aagacaattt
    10921 gatcaataat ggttcacaat ttgacggtgg ggcagatatc caaaactttg ccaacggtca
    10981 aacatcttac acaatccttt gggcaccagc tcaaaatggt atccaagcta aacttttaga
    11041 agcaagtaag gtagaagtgg tagaagtacc attcccatca gacgaaggta agccagctct
    11101 tgaatacctt gtaaacgggt ttgcagtatt caacaataaa gacgacaaga aagtcgctgc
    11161 atctaagaaa ttcatccagt ttatcgcaga tgacaaggag tggggaccta aagacgtagt
    11221 tcgtacaggt gctttcccag tccgtacttc atttggaaaa ctttatgaag acaaacgcat
    11281 ggaaacaatc agcggctgga ctcaatacta ctcaccatac tacaacacta ttgatggatt
    11341 tgctgaaatg agaacacttt ggttcccaat gttgcaatct gtatcaaatg gtgacgaaaa
    11401 accagcggat gctttgaaag ccttcactga aaaagcaaac gaaacaatca aaaaagctat
    11461 gaaacaatag ttcttagtta ttctataaaa agtagttttt taaagaacct aagagtgtat
    11521 accccctttt ccctctacac agatagtgta agaaaagggg gcttttgttt aaaatgtaag
    11581 aaactgtcac gaaattaaaa tgaagttctt acataagcga atcataaaaa atttcatttt
    11641 gattttaaaa cagttcaaga aagtcaaaaa attattctat ttgaaagaga ggtgccgact
    11701 gtgaaagtca ataaaatccg tatgcgggaa acagtgattt cctacgcttt cctagcacca
    11761 gtattattct tctttgtcat ctttgtgttg gctccgatgg tgatgggctt cattacaagt
    11821 ttctttaact actcaatgac taaatttgag tttgtaggct tggataacta tatccgtatg
    11881 tttaaagatc ctgtctttac aaaatctctg attaacacag ttattttggt tattggatct
    11941 gtaccagttg ttgttctatt ctcactcttt gtagcatctc agacctatca tcaaaatgtc
    12001 attgccagat ccttctaccg tttcgtcttc ttccttcctg ttgtaacggg tagtgttgcc
    12061 gtgacagttg tttggaaatg gatttatgac ccactatcag ggattctaaa ctttgtcctt
    12121 aagtccagcc acatcatcag ccaaaacatt tcttggttgg gagataaaaa ctgggcattg
    12181 atggcgatta tgattattct cttgaccact tcagttggtc agcccatcat cctttatatc
    12241 gctgccatgg ggaatattga caattcactg gttgaagcgg cgcgtgttga tggtgcaact
    12301 gagtttcaag ttttttggaa gattaaatgg ccaagccttc ttccaacaac tctttatatt
    12361 gcaatcatca caacaattaa ctcattccag tgtttcgcct tgattcagct tttgacatct
    12421 ggtggtccaa actactcaac aagtaccttg atgtactacc tttacgaaaa agccttccaa
    12481 ttgacagaat acggctatgc caacacaatt ggtgtcttct tggcagtcat gattgctatc
    12541 gtaagctttg ttcaatttaa agtacttgga aacgacgtag aatactaaag aaaggagaca
    12601 gctatgcaat ctacagaaaa aaaaccatta acagccttta ctgttatttc aacaatcatt
    12661 ttgctcttgt tgactgtgct gttcatcttt ccattctact ggattttgac aggggcattc
    12721 aaatcacaac ctgatacaat tgttattcct cctcagtggt tccctaaaat gccaaccatg
    12781 gaaaacttcc aacaactcat ggtgcagaac cctgccttgc aatggatgtg gaactcagta
    12841 tttatctcat tggtaaccat gttcttagtt tgtgcaacct catctctagc aggttatgta
    12901 ttggctaaaa aacgtttcta tggtcaacgc attctatttg ctatctttat cgctgctatg
    12961 gcgcttccaa aacaagttgt ccttgtacca ttggtacgta tcgtcaactt catgggaatc
    13021 cacgatactc tctgggcagt tatcttgcct ttgattggat ggccattcgg tgtcttcctc
    13081 atgaaacaat ttagtgaaaa tattcctaca gagttgcttg aatcagctaa aatcgacggt
    13141 tgtggtgaga ttcgtacctt ctggagtgta gccttcccga ttgtgaaacc agggtttgca
    13201 gcccttgcaa tctttacctt catcaatact tggaatgact acttcatgca attggtaatg
    13261 ttgacttcac gtaacaattt gaccatctca cttggggttg cgaccatgca ggctgaaatg
    13321 gcaaccaact atggtttgat tatggcagga gctgcccttg ctgctgttcc aatcgtcaca
    13381 gtcttccttg tcttccaaaa atccttcaca cagggtatta ctatgggagc ggtcaaagga
    13441 taatactctg cgaaaatctc ttcaaactac gtcagcttca ccttgccata cttaagtatt
    13501 gcctgcggtt agcttcctag tttgttcttc aattttcatt gagtatagga aaatcaatct
    13561 atcaagatac agaagtatat tttatagatt tagagaatat agaggttata agtgtctaca
    13621 aaatggaggg tatgcagtta ctttatgaag ttttgtcaga cacttataaa cttaagaatg
    13681 gttttagtta actatcagaa acgaaggaaa gagtatgatt tttgacgatt tgaaaaacat
    13741 caccttttac aaagggattc atcctaattt agacaaggct atcgactatc tctaccaaca
    13801 tcgtaaggat tctttcgaat taggaaagta tgatattgat ggagataaag tctttctagt
    13861 tgttcaggaa aatgtcctca atcaagctga aaatgatcaa tttgagtatc ataagaacta
    13921 tgcagatttg catttgctgg tagaaggaca tgaatattcg agctacggtt cacgtatcaa
    13981 agacgaggca gtagcattcg acgaagcgag tgacattggc tttgttcatt gtcatgaaca
    14041 ctacccactc ttgttgggtt atcacaattt tgcgattttc ttcccaggtg agccacatca
    14101 gccaaatggt tatgcaggca tggaagaaaa ggttcgaaaa tatctcttta aaattttgat
    14161 tgattaaaaa taggatgaat tgtttttttg taaagctttg ataatactct accatgaaat
    14221 tgatctttgt gaggtagaga aatgagaata aaatatttaa aaattggtat cttcttgtca
    14281 gtctgtgtat gctacaagag ctagtttctt ggatggacag ggaattacag ttgatgagat
    14341 ggcttggata attaggggca ttgtgaatgc attgattggt agatacataa aattaggtac
    14401 ttatgcggct aagtatggta ttagtatggc acgctcgatc ttaagtaggg cagctgcaac
    14461 tgcagcagca agagtaggat tatcgaccaa gatttctgga tggattttac gagtagctgt
    14521 gaatgtagct gatgtatatg gtaattttgc caacaatatt gctgcagctt gggatgcaca
    14581 tgataaaatc cctaacaatg gtcgtataaa cttttaaaat gcgagaatga aagcactttg
    14641 tattttttta ttgaatatgt tagcttggac agtgcttgca atgataattc gtggagggct
    14701 agatggattt gatgagcata cttggagtac tattttaatt gcttcgctgt tcggggtata
    14761 tgattataag cccatagata aaaatagaaa aagtccaaaa gaaaaaagaa aaaatagatt
    14821 tgttcatggt agggatttat gaaagcttta ctgacaaaaa agaaaacagt ttacaaagaa
    14881 aaatgatgga ggagcaaaca tggcacaaaa aggagtaagc cttatcaagg cagcatttga
    14941 tacagacaac tttctcatgc gttttagtga gaaagtcttg gacatcgtga cagccaatct
    15001 tctttttgtc gtctcttgtt tgcccatcgt gacgattgga gtagctaaaa tcagcctcta
    15061 cgagaccatg ttcgaagtta agaagagcag acgggtgcct gtttttaaaa tctatctaag
    15121 atctttcaag caaaatctga aactaggtct tcagctgggt ttaatggagt taggaattgt
    15181 gtttcttacc ctttcagatc tctatctttt ctggggtcaa acagctctgc ccttccaatt
    15241 gctgaaagcc atttgtttag gtattctgat ttttcttact atcgtgatgc tggctagtta
    15301 ccctatcgcg gcacgttatg acctatcttg gaaagaagtg ttacaaaaag ggcttatctt
    15361 ggcaagtttt aactttcctt ggttcttcct catgttagcc attcttgtcc tcattgtgat
    15421 ggttctttat ctgtctgcct tcagtctact cttaggtggc tcagccttcc tactttttgg
    15481 gtttggactt cttgcttttt tacaagtggg agtgatggaa aagctatttg ctaagtatga
    15541 gtaaggggtg caattatttc tgaaactact ttcaaaggct ccaaacgcta ttctataagc
    15601 gagaaactaa aatctaagtg tctataagat attgaaagcc ttttcggtaa agtgtatact
    15661 aaagaagtaa agaaaaatct gctttagcag aaaataaaaa taataggaga aaatctatgt
    15721 cagatttgaa aaaatacgaa ggtgtcattc cagccttcta cgcatgttat gatgatcaag
    15781 gagaagtaag cccagaacgt acgcgtgcct tggttcaata cttcattgat aaaggtgttc
    15841 aaggtcttta tgtcaatggt tcttctggtg aatgtatcta ccaaagcgtt gaagatcgca
    15901 agttgatttt ggaagaagtc atggcggtag ccaaaggtaa attgaccatt attgcccatg
    15961 ttgcttgcaa taatactaaa gatagtatgg aacttgctcg ccatgctgaa agcttgggag
    16021 tagatgctat tgcaacgatt ccaccaattt atttccgctt gccagaatac tcagttgcca
    16081 aatactggaa cgatatcagt tctgcagctc caaacacaga ctacgtgatt tacaacattc
    16141 ctcaattggc aggggttgct ttgactccaa gcctttacac agaaatattg aaaaatcctc
    16201 gtgttatcgg tgtgaagaac tcttctatgc cagttcaaga tatccaaacc tttgtcagcc
    16261 ttggtggaga agaccatatc gtctttaatg gtcctgatga gcagttccta ggtggccgcc
    16321 tcatgggtgc taaggctggt atcggtggta cttatggtgc tatgccagaa ctcttcttga
    16381 aactcaatca gttgattgcg gataaggacc tagaaacagc gcgtgaattg cagtatgcta
    16441 tcaacgcaat cattggtaaa ctcacttctg ctcatggaaa tatgtacggt gtcatcaaag
    16501 aagtcttgaa aatcaatgaa ggcttgaata ttggatctgt tcgttcacca ttgacaccag
    16561 taattgaaga agatcgtcca gttgtagaag cggctgcagc cttgattcgt gaaaccaagg
    16621 agcgcttcct ctaatctaaa aggaggtatt tatgacatac tacgttgcaa ttgatatcgg
    16681 tggaactaac atcaagtatg gtttggttga tcaagagggg caacttcttg aatcacatga
    16741 aatgccaaca gaggcgcata agggtggacc tcatatctta caaaagacca aagatatcgt
    16801 agctagttat ttagaaaaag gcccagtagc aggtgttgcc atatcttctg ctgggatggt
    16861 ggatccggat aagggtgaga ttttctatgc tgggccgcaa atccctaact acgcaggcac
    16921 ccagttcaaa aaggaaatcg aagaaagctt tactattcct tgtgagattg aaaatgatgt
    16981 caactgtgca ggtcttgctg aggcagtatc tggttcaggc aagggagcaa gtgtgacact
    17041 ttgcttgacc attggaaccg gtatcggtgg ttgcttgatt atggatagga aagtcttcca
    17101 tggttttagt aattcagcct gtgaagtcgg gtatatgcat atgcaggatg gagcttttca
    17161 ggatctcgct tctacaacag ctttagtgaa atatgtagct gaagcccatg gagaagatgt
    17221 tgatcagtgg aatggccgac gtatctttaa ggaagctact gaaggaaaca aaatctgcat
    17281 ggaaggtatt gaccgtatgg ttgactatct aggaaaaggt ctggcaaata tttgctacgt
    17341 tgccaatcca gaagtggtca ttcttggtgg tggtatcatg gggcaagagg ctatcctcaa
    17401 acctaagatc cgcacagcct tgaaagaggc tttggtacca agtttagcag aaaaaacacg
    17461 attagaattt gcccatcacc aaaatacagc agggatgttg ggtgcatatt atcattttaa
    17521 gacaaaacaa tcctagtttg gctcagccaa actaggattt tcttacacgt ttttgtctac
    17581 gatagccgtt gagtttttta ttttcccagt agctattaaa gattttttcc ttgctttcgc
    17641 gattgatttc caaaaagtag gcataaatca aatcgataaa gaagagcata ggaagttgag
    17701 cggatattcg ttggatatag gagggttggc tgtgggtggc tacaagaaca gtctctgtat
    17761 aggtctggct atctttattg ggaacacttg taaagagtac agtctttgcc cccatctcct
    17821 tggcatctaa tagactatct aaaatagaag gagttgagcc tgaaagtgag aagcccagta
    17881 ctagacaatt ttcatccatg atgctggttg tccaggcaaa gccgtcttgg tctgtcaaag
    17941 cttcgcagac cacacctaat cgcataaaac gtaatttcat ttcacgggcg acgaggccag
    18001 aactccctgt tccaaagaag tagatacgct cagcatcttc gattagctgg gcaattcgtt
    18061 ctagttggat ttcgtcaatc aagtcttgtg tttgttccct catattgcta taacttctga
    18121 ggactcgttt ggtcagtgga ctgtgcttgg agacttggtt ggcttgattt tctgcctgat
    18181 gttggtattg gaaaataaat tctcggtagc cagtaaagcc acacttttta gcaaagcggg
    18241 tcaaagcagc ttgagaaata tgtaattttt gggtgacttg ttgagaagat aaatcatctg
    18301 taatcgtttc agcttgcaaa aaatagcgag cgatttcttg ctctaggtct gtcatttctt
    18361 caaaatgtga atcaatgata gttgcgatat ctggtttgtc catagggaaa gctcctttac
    18421 atgagtcata ctggaagact agatcaggga atagtcacac ttcattataa cacataatat
    18481 aaggatagat aaataaaaac gcatctctgt tttaaaaacg aaaaaatcga aaaagcttct
    18541 ctcttttcca taattttcta ctcaaattgt ggtacaatta agagtaagat tttaagttag
    18601 aaatgagact gatttgtatg agaaaattta acagccattc gattccgatt cggcttaatt
    18661 tattgttttc aatcgtcatt ttactcttta tgaccattat tggtcgtttg ttgtatatgc
    18721 aggttttgaa caaggatttt tacgaaaaaa agctagcctc agctagtcag accaagatta
    18781 caagcagttc agcccgtggg gaaatttatg atgctagtgg aaaacctttg gtagaaaata
    18841 cgttaaagca ggttgtttcc tttacgcgta gcaataaaat gacggctaca gacttaaaag
    18901 aaacagctaa aaagttactg acttatgtga gcatcagttc tccaaatttg acagaacgcc
    18961 agctggcgga ttactatttg gctgatcctg aaatctataa aaaaacagtg gaagctctcc
    19021 caagcgagaa acgcttggat tcagatggca atcgtctatc tgaatcagaa ctgtataaca
    19081 atgcggtcga tagtgtacaa acgagtcaac taaactatac agaggatgaa aagaaagaaa
    19141 tctatctttt tagtcagtta aatgctgttg gaaactttgc gacaggaacc attgcgacag
    19201 atcctctaaa tgattctcag gtggctgtta ttgcctctat ttcaaaggag ctgcctggca
    19261 ttagtatttc tacttcttgg gatagaaagg ttttggaaac ttccctttct tctatagttg
    19321 ggagtgtatc cagtgaaaaa gctggtctcc cagcggaaga agcagaagcc tatcttaaaa
    19381 aaggctattc tctaaatgat cgtgtaggaa cctcctattt ggaaaagcaa tatgaagaga
    19441 ccttacaagg aaaacgctcg gtaaaagaaa tccatctgga taaatatggc aatatggaaa
    19501 gcgtggatac aattgaggaa ggtagtaagg gaaacaatat caaactgacc attgatttgg
    19561 ccttccaaga tagcgtggat gctttactga aaagttattt caattccgag ctagaaaatg
    19621 gtggagccaa gtattctgaa ggtgtctatg cagtcgccct taacccaaaa acaggtgcgg
    19681 ttttgtctat gtcagggatt aaacatgact tgaaaacggg agagttgacg cctgattcct
    19741 tgggaacggt aaccaatgtc tttgttccag gttcggttgt caaggcggcg accatcagct
    19801 caggttggga aaatggagtc ttgtcaggaa accagacctt gacagaccag tccattgtct
    19861 tccaaggttc agctcccatc aattcttggt atactcaggc ttacggttca ttccctatca
    19921 cagcggtcca agctctggag tattcatcaa atacctatat ggtccaaaca gccttaggtc
    19981 ttatggggca aacctatcaa cccaatatgt ttgtcggcac cagcaatcta gagtctgcta
    20041 tggagaaatt gcgttcaacc tttggcgaat atggcttggg tactgcgaca ggaattgacc
    20101 taccagatga atctactgga tttgttccca aagagtatag ctttgctaat tacattacta
    20161 atgcctttgg gcagtttgat aactatacgc cgatgcagtt ggctcagtat gtagcaacta
    20221 ttgcaaataa tggtgttcgt gtggctcctc gtattgttga aggcatttat ggtaataatg
    20281 ataagggagg actgggtgac ttgattcagc aactgcaacc gacagagatg aataaggtca
    20341 atatatccga ctccgatatg agcatcttgc accaaggttt ttatcaggtt gcccatggta
    20401 ctagtggatt gacaactgga cgtgcctttt caaatggtgc cttggtatcc attagcggaa
    20461 aaacaggtac agccgaaagc tatgtggcag atggtcagca agcaaccaat accaatgcgg
    20521 tggcctatgc cccatctgat aatccccaaa tcgctgtcgc agtggtcttt cctcataata
    20581 ccaatctaac aaatggtgta ggaccttcca ttgcgcgtga cattatcaat ctgtatcaaa
    20641 aataccatcc aatgaactag aaaggaaatt atgctttatc caacacctat tgccaagttg
    20701 attgacagtt attctaagtt accaggtatc gggattaaga cggctacgcg tctggccttt
    20761 tatacgattg ggatgtctgc tgatgatgtc aatgaatttg caaaaaatct cctttctgct
    20821 aagagagaat tgacatattg ttctatttgt ggacgtttga cagacgacga tccttgttct
    20881 atctgtactg atccgactcg tgaccagaca acaattttag ttcttgagga tagtagagat
    20941 gtggcagcca tggaaaatat ccaagaatac catggactct atcatgtcct gcatggcctc
    21001 atttctccta tgaatggtat cagtccggac gatatcaatc tcaagagcct tatgactcgt
    21061 cttatggata gtgaggtttc agaagtgatt gtggcgacta atgctacagc ggatggtgaa
    21121 gcgacttcca tgtatctttc acgtttgctc aagccggctg gtatcaaggt tacgcgtcta
    21181 gcacgaggtc tcgctgtggg agcggacatt gagtatgcgg acgaagtgac actcttacga
    21241 gcgattgaaa atcggacaga gttgtaagtg taggcaaatt tacgaactcc cttcatttat
    21301 aaaaaatcaa agaggctgaa aatcgttcct atcggcctct ttttgtatag tgtgatgagt
    21361 aggatcgggt tcaagtttta aaaaaccaag caaatatgat atactaaaga gcgagtattc
    21421 tagtagaatt aggacaaata atatgaaaca aacgattatt cttttatatg gtggacggag
    21481 tgcggaacgc gaagtctctg tcctttcagc tgagagtgtc atgcgtgcgg tcaattacga
    21541 ccgtttcaca gtcaagactt tctttatcag tcagtcaggt gactttatca aaacacagga
    21601 atttagtcat gctccggggc aagaagaccg tctcatgacc aatgaaacca ttgattggga
    21661 taagaaagtt gcaccaagtg ctatctacga agaaggtgca gtggtctttc cagtccttca
    21721 cgggccaatg ggagaagatg gctctgttca aggattcttg gaagttttga aaatgcctta
    21781 cgttggttgc aacattttgt catcaagtct tgccatggat aaaatcacga ctaagcgtgt
    21841 tctggaatct gctggtattg cccaagttcc ttatgtggct atcgttgaag gcgatgatgt
    21901 gactgctaaa atcgctgaag tggaagaaaa attggcttat ccagtcttca ctaagccgtc
    21961 aaacatgggg tctagtgtcg gtatttctaa gtctgaaaac caagaagaac tccgtcaagc
    22021 cttaaaactt gccttccgat atgacagccg tgtcttggtt gagcaaggag tgaatgcccg
    22081 tgaaattgag gttggcctct tgggtaacta cgatgtcaag agcacgctac ctggagaagt
    22141 tgtcaaggac gttgcctttt atgactacga tgccaagtat attgataaca agattactat
    22201 ggatattcct gccaaaatca gtgatgatgt ggtggctgtc atgcgtcaaa atgcagaaac
    22261 agccttccgt gccattggtg gccttggtct atctcgttgc gatttcttct atacagataa
    22321 gggagagatt tttctcaacg agctcaatac catgccaggt tttacccagt ggtctatgta
    22381 cccactactt tgggacaata tggggatcag ctacccagga ctaatcgagc gtttggttga
    22441 ccttgccaag gaaagctttg acaagcgcga agcgcatttg atataaaatg aaagagaggg
    22501 tagaagccag aaccatcact gcacggtgac tagagttctc ggacttcagc cctttttaaa
    22561 ggagtagaaa tgaaattaac aatccatgaa attgcccaag ttgttggagc caaaaatgat
    22621 atcagtatct ttgaggacac ccagttagaa aaagctgagt ttgatagtcg tttgattgga
    22681 actggagatt tatttgtgcc acttaaaggt gcgcgtgatg gccatgactt tattgaaaca
    22741 gcctttgaaa atggtgcagc agtaaccttg tctgagaaag aggtctcaaa tcatccttac
    22801 attttagtag atgatgtttt gacagccttt caatccctag catcctacta tcttgaaaaa
    22861 acgactgttg atgtctttgc tgttacaggt tcaaatggca agacaacgac taaggatatg
    22921 ttggcgcatt tactgtcaac aagatacaag acctacaaaa cacaaggcaa ttacaataat
    22981 gagattggcc ttccttacac agttctccac atgcctgaag gaacagaaaa gttggtcttg
    23041 gagatgggac aggatcactt gggcgatatt catctcttgt ctgaattggc tcgtccaaaa
    23101 acagccatcg tgaccttggt tggagaagcc catttggcct ttttcaaaga ccgttcagag
    23161 attgctaagg gaaaaatgca aattgcagac ggaatggctt caggttcctt gcttttagcg
    23221 ccggctgacc ctatcgtaga ggactatttg ccaactgata aaaaggtggt tcgttttggg
    23281 caaggggcag agctggaaat tactgacttg gttgagcgca aagatagtct gaccttcaag
    23341 gccaatttct tagagcaagc ccttgatttg ccagtaactg gcaagtacaa tgcgacaaat
    23401 gctatgattg catcctatgt tgccttgcaa gaaggagttt cagaggagca aattcgtttg
    23461 gccttccaag atcttgaatt gacgcgtaac cgtaccgagt ggaagaaagc agccaatgga
    23521 gcagatatcc tgtcagatgt ttacaatgcc aatccaactg ctatgaaact gattttagag
    23581 actttctctg ccattccagc caatgaaggt ggcaagaaaa ttgcagtgtt ggcggatatg
    23641 aaggagcttg gtgaccagtc tgttcaactt cataatcaga tgattttgag cctttctcca
    23701 gatgtgcttg ataccgtgat tttctatgga caagatattg ctcagttggc tcaattggcc
    23761 agtcaaatgt tcccaatcgg ccacgtttac tacttcaaga aaacagaaga ccaggatcaa
    23821 tttgaagacc tagtcaagca ggtcaaggaa agccttggag cccatgacca aatcctgctc
    23881 aaaggctcta actctatgaa tctagccaag ttggtagaaa gtttagaaaa tgaagacaag
    23941 tgattttgtc aagtatttgc aaagaatgat tgccattaca gatactggct taacctttac
    24001 aaaagatccg tttgaccgtg agcgctacga agacttgcga agtctgttat ctgaaatgtt
    24061 gaatcaagca tcagaccttg attccgaaga agtggcagaa gtcttgaagc caacttctgc
    24121 ttatgcgact cccttaatgg acgtccgtgc ttggattgtt gaggatgaga agatttgtct
    24181 ggttagggga caaggagagg atagttgggc tttgccaggt ggctttggtg aagtcggcta
    24241 ttctccaaca gaaaatattc tcaaggaaat tgaagaagaa accggtttta aagccaaagt
    24301 tgaaagactg ctagctgttt ttgataccaa tcgtttccaa ctacagagca aacagtatac
    24361 aaagtttgtt tttggatgta agcttcttga tggacaattc caagaaaatc aagaaattgc
    24421 tgaccttcaa ttttttgcca ttgaccaact gccgaactta tctgaaaaac gcattaccaa
    24481 ggagcaaata gagcttcttt ggcaggttta tcaaggtcat agggggcaat atcttgacta
    24541 agaagatgat tatcgtattt ctaaatccat ttttaacaac tagcatggta taataatatg
    24601 caggaaaatt ttgaattatg aggaagacta gatgaattta tgggatattt tctttacgac
    24661 tcaggcaacc gagccgccca aatttgacct tttttggtat gttagcctat ttacgctctt
    24721 agccttaacc ttttatacag cccatcgcta tcgtgaaaag aaggtttacc aacgattttt
    24781 ccaaatcttg cagactgttc agttaatcct tctttatggt tggtactggg tcaatcatat
    24841 gccactgtca gaaagcctac ccttttacca ttgccgtatg gctatgtttg tggtactctt
    24901 gcttcctggt caatccaaat ataaacaata ctttgcatta ttgggaacat ttgggacatt
    24961 agcagccttt gtttatccag tgccagatgc ttaccctttt ccacatatca ccattctatc
    25021 ctttatcttt ggtcatttag cactcttggg gaactctcta gtttatctat tgagacagta
    25081 taatgcgcga ttgctggatg tgaagggaat ttttctcatg acctttgccc taaatgcctt
    25141 gatttttgtg gtcaatttgg tgacaggtgg cgattacgga tttttgacaa aaccgccatt
    25201 ggttggggat cacggtctag tagctaatta tttacttgtt tcaattgtgc tggtagctac
    25261 tatcagtttg actaagaaaa tcttagaatt ctttttagct caagaagcag aaaaaatgat
    25321 tgcaaaggaa gcttaacaca gagctttctt ttttgctctt agagagtttt tacaagcagc
    25381 ttataaaata agaatttctg aatagacaaa ctcaaaaaat ggctgggaaa tttaggaaaa
    25441 aagcaagcac gattaaattt tttgtgttat aatattttgt gaatagctat gcctatgttt
    25501 agctatggaa taatacgaag tgcgaaactt ggaagataga gaggaagcga tgtaatggct
    25561 agagaaggct tttttacagg tctagatatt ggaacaagct ctgtcaaggt gcttgtggcc
    25621 gagcagagaa atggtgaatt aaatgtaatt ggcgtgagta atgccaaaag taaaggtgta
    25681 aaggatggaa ttattgttga tattgatgca gcagcaactg ctatcaagtc agccatttcc
    25741 caagcggaag aaaaggcagg catttcgatt aaatcagtga atgtcggctt gcctggtaat
    25801 cttttgcagg tagaaccaac tcaggggatg attccagtaa catctgatac taaggaaatt
    25861 acggatcaag atgttgaaaa tgttgtcaaa tcagctttga caaagagtat gacacctgac
    25921 cgtgaagtca ttacctttat tcctgaagaa tttattgtgg atggtttcca agggattcgt
    25981 gacccacgtg gcatgatggg ggttcgcctt gaaatgcgtg gtttgcttta tacaggacct
    26041 cgtactatct tgcacaattt gcgtaagacg gttgagcgtg caggtgttca ggttgaaaat
    26101 gttatcattt caccactagc aatggttcag tctgttttga acgaagggga acgtgaattt
    26161 ggtgctacag tgattgatat gggggcaggt caaacgactg tcgctacaat ccgtaatcaa
    26221 gaactccagt tcacacatat tctccaagaa ggtggagatt atgtaactaa agatatctcc
    26281 aaggttttga aaacctctcg caaattagcg gaaggcttga aactgaatta cggggaagcc
    26341 tatccgcctc ttgcaagcaa agaaaccttc caagtagagg ttattggaga agtagaagca
    26401 gtcgaagtga cggaagccta cttgtcagaa attatttctg cacgaatcaa gcacatcctt
    26461 gaacaaatca agcaagaatt agatagaagg cgtctattgg acctccctgg tggtattgtc
    26521 ttaatcggtg ggaatgccat tttaccaggt atggttgagc ttgctcagga agtctttggc
    26581 gtccgtgtca agctttatgt tccaaatcaa gttggtatcc gtaatccagc ctttgcgcat
    26641 gtgattagtt tatcagaatt tgcgggtcaa ttaacagaag ttaatctttt ggctcaggga
    26701 gcgataaaag gtgagaatga cttaagtcat cagccaatta gttttggtgg gatgctgcaa
    26761 aaaacagctc agtttgtaca atcaacgcct gttcaaccag ctcctgctcc agaagtagag
    26821 ccggtggcgc ctacagaacc aatggcggat ttccaacaag cttcacaaaa taaaccgaaa
    26881 ttagcagatc gtttccgtgg attgatcgga agcatgtttg acgaataaag aggaaaaata
    26941 aattatgaca ttttcatttg atacagctgc tgctcaaggg gcagtgatta aagtaattgg
    27001 tgtcggtgga ggtggtggca atgccatcaa ccgtatggtc gacgaaggtg ttacaggcgt
    27061 agaatttatc gcagcaaaca cagatgtaca agcattgagt agtacaaaag ctgagactgt
    27121 tattcagttg ggacctaaat tgactcgtgg tttgggtgca ggaggtcaac ctgaggttgg
    27181 tcgtaaagcc gctgaagaaa gcgaagaaac actgacggaa gctattagtg gtgccgatat
    27241 ggtcttcatc actgctggta tgggaggagg ctctggaact ggagctgctc ctgttattgc
    27301 tcgtatcgcc aaagatttag gtgcgcttac agttggtgtt gtaacacgtc cctttggttt
    27361 tgaaggaagt aagcgtggac aatttgctgt agaaggaatc aatcaacttc gtgagcatgt
    27421 agacactcta ttgattatct caaacaacaa tttgcttgaa attgttgata agaaaacacc
    27481 gcttttggag gctcttagcg aagcggataa cgttcttcgt caaggtgttc aagggattac
    27541 cgatttgatt accaatccag gattgattaa ccttgacttt gccgatgtga aaacggtaat
    27601 ggcaaacaaa gggaatgctc ttatgggtat tggtatcggt agtggagaag aacgtgtggt
    27661 agaagcggca cgtaaggcaa tctattcacc acttcttgaa acaactattg acggtgctga
    27721 ggatgttatc gtcaacgtta ctggtggtct tgacttaacc ttgattgagg cagaagaggc
    27781 ttcacaaatt gtgaaccagg cagcaggtca aggagtgaac atctggctcg gtacttcaat
    27841 tgatgaaagt atgcgtgatg aaattcgtgt aacagttgtt gcaacgggtg ttcgtcaaga
    27901 ccgcgtagaa aaggttgtgg ctccacaagc tagatctgct actaactacc gtgagacagt
    27961 gaaaccagct cattcacatg gctttgatcg tcattttgat atggcagaaa cagttgaatt
    28021 gccaaaacaa aatccacgtc gtttggaacc aactcaggca tctgcttttg gtgattggga
    28081 tcttcgccgt gaatcgattg ttcgtacaac agattcagtc gtttctccag tcgagcgctt
    28141 tgaagcccca atttcacaag atgaagatga attggataca cctccatttt tcaaaaatcg
    28201 ttaagtaaat gaatgtaaaa gaaaatacag aacttgtttt tcgagaagtt gcagaggcta
    28261 gtctgagtgc tcatcgagag agtggttcgg tctctgtcat tgcagttacc aagtatgtag
    28321 atgtaccgac agcggaagcc ttgcttccgc taggtgtcca tcatatcggt gaaaatcgtg
    28381 tagataagtt tctggaaaaa tatgaagctt taaaagatcg agatgtgact tggcatttga
    28441 ttggtacctt gcaaagacgt aaggtgaaag atgtcattca atacgttgat tatttccatg
    28501 cattggactc agtaaagtta gcaggggaaa ttcaaaaaag aagtgaccga gtcatcaagt
    28561 gtttccttca agtaaatatt tctaaagaag aaagcaaaca cggtttttcg agagaggaac
    28621 tgctggaaat cttgccagag ttagccagac tagataagat tgaatatgtt ggtttaatga
    28681 cgatggcacc ttttgaggct agcagtgagc agttgaaaga gattttcaag gcggcccaag
    28741 atttacaaag agaaattcaa gagaaacaaa ttccaaatat gcctatgacc gagttaagta
    28801 tgggaatgag tcgtgattat aaagaagcga ttcaattcgg ttccactttt gttcgtatag
    28861 gtacatcatt ttttaagtag gagagaacca tgtctttaaa agatagattc gatagattta
    28921 tagattattt tacggaggat gaggattcaa gtctccctta tgaaaaaaga gatgagcctg
    28981 tgtttacttc agtaaattct tcacaggaac cggctctccc aatgaatcaa ccttcacagt
    29041 cggctggcac aaaagagaac aatatcacca gacttcatgc aagacaacag gaattggcaa
    29101 atcagagtca gcgtgcaacg gataaggtca ttatagatgt tcgttatcct agaaaatatg
    29161 aggatgcaac agaaattgtt gatttattgg caggaaacga aagtatcttg attgattttc
    29221 agtatatgac agaggtgcag gctcgtcgtt gtttggacta tttggatgga gcttgtcatg
    29281 ttttagctgg aaatttgaaa aaggtagctt ctaccatgta tttgttgaca ccagtgaacg
    29341 ttattgtaaa tgttgaagat atccgtttac cagatgaaga tcaacagggt gagttcggtt
    29401 ttgatatgaa gcgaaataga gtacgataat gattttttta attcgtatga tttataatgc
    29461 agtggatatt tactccctaa ttttggtagc cttcgctgtc atgtcttggt ttccaggtgc
    29521 ctacgaatcc agtttaggtc gttggattgt agcgttggta aaaccagtgc ttgctccctt
    29581 gcaacgcctg cctttacaga tagcgggtct tgatttatct gtttgggttg cgattgtttt
    29641 ggttcgattt ttaggagaaa acctagtgcg ttttctggcg atgataggat gaataaaggg
    29701 atttatcagc atttctccat agaagatcgt ccatttcttg acaagggaat ggaatggata
    29761 aagaaggtag aagatagcta tgctcctttt ttaactcctt ttatcaatcc tcatcaggag
    29821 aagctattaa agattttggc caaaacctat ggtcttgctt gtagcagtag tggggaattc
    29881 gtctcgagtg agtatgttcg agttttatta tacccagatt atttccaacc agagttttca
    29941 gattttgaaa tatctctcca ggaaattgtg tattccaata aatttgaata tttaacgcat
    30001 gctaagattt tagggacagt catcaatcaa ttagggattg aacggaaact ttttggagat
    30061 atcctagtag atgaagaacg ggcgcagatt atgattaatc agcagtttct tctcctcttt
    30121 caagatggat taaagaaaat tggtcgtata cctgtttcgc tggaggaacg tcctttcacc
    30181 gagaaaatag ataagctaga acagtatcga gaactggatt tatctgtgtc tagttttcga
    30241 ttagatgttc ttttatcaaa tgttttgaaa ctatctagga atcaagcaaa ccagttgatt
    30301 gaaaagaaac ttgtccaagt aaattatcat gtggtagaca aatcagatta cactgttcaa
    30361 gttggagact tgattagtgt gagaaaattt ggtcgcttga gattacttca agataaggga
    30421 caaacgaaaa aagagaagaa aaaaataacc gtccagttat tattaagtaa gtgaggaata
    30481 gaatgccaat tacatcatta gaaataaagg acaagacttt tggaactcga ttcagaggtt
    30541 ttgatccaga agaagtcgat gaatttttag atattgtggt tcgtgattac gaagatcttg
    30601 tgcgtgcgaa tcatgataaa aatttgcgta ttaagagttt agaagagcgt ttgtcttact
    30661 ttgatgaaat aaaagattca ttgagccagt ctgtattgat tgcccaggat acagctgagc
    30721 gagtgaaaca ggcggcgcat gaacgttcaa acaatatcat tcatcaagca gagcaagatg
    30781 cgcaacgctt gttggaagaa gctaaatata aggcaaacga gattcttcgt caagcaactg
    30841 ataatgctaa gaaagtcgct gttgaaacag aagaattgaa gaacaagagc cgtgtcttcc
    30901 accaacgtct caaatctaca attgagagtc agttggctat tgttgaatct tcagattggg
    30961 aagatattct ccgtccaaca gctacttatc ttcaaaccag tgatgaagcc tttaaagaag
    31021 tggttagcga agtacttgga gaaccgattc cagctccaat tgaagaagaa ccaattgata
    31081 tgacacgtca gttctctcaa gcagaaatgg aagaattaca agctcgtatt gaggtagccg
    31141 ataaagaatt gtctgaattt gaagctcaga ttaaacagga agtggaaact ccaactcctg
    31201 tagtgagtcc tcaagttgaa gaagagcctc tgctcatcca gttggcccaa tgtatgaaga
    31261 accagaagta gctccagtgc atccgacagg tccaacacca gctacagaaa ctgttgattc
    31321 agcaccggga tttgaagcac cgcaagaatc tgttacaatt ttataagaaa tattctgaga
    31381 acaatatctt atccttatat tcccagcgag caggagatgg tgtgagtcct gcattcccta
    31441 tcgataagat tatcctctca aactatcaag tctgaatcta gtaagatttg acgttcccca
    31501 cgttacggga taagagggag aaagactaaa actttttccg aataaaggtg gtaccacgat
    31561 tttcgtcctt tttggaagtc gtggttttta atttgttatt atttataaag gagataccat
    31621 gaaactcaaa gacaccctta atcttgggaa aactgaattc ccaatgcgtg caggccttcc
    31681 taccaaagag ccagtttggc aaaaggaatg ggaagatgca aaactttatc aacgtcgtca
    31741 agaattgaac caaggaaaac ctcatttcac cttgcatgat ggccctccat acgctaacgg
    31801 aaatatccac gttggacatg ctatgaacaa gatttcaaaa gatattattg ttcgttctaa
    31861 gtctatgtca ggattttacg caccatttat tcctggttgg gatactcatg gtctgccaat
    31921 cgagcaagta ttgtcaaaac aaggtgtcaa acgtaaagaa atggacttgg ttgagtactt
    31981 gaaactttgc cgtgagtacg ctctttctca agtagataaa caacgtgaag attttaaacg
    32041 tttgggtgtt tctggtgact gggaaaatcc atatgtgacc ttgactcctg actatgaagc
    32101 agctcaaatt cgtgtatttg gtgagatggc taataagggt tatatctacc gtggtgccaa
    32161 gccagtttac tggtcatggt catctgagtc agcccttgct gaagcagaga ttgaatacca
    32221 tgacttggtt tcaacttccc tttactatgc caacaaggta aaagatggca aaggagttct
    32281 agatacagat acttatatcg ttgtctggac aacgactcca tttaccatca cagcttctcg
    32341 tggtttgacg gttggtgcag atattgatta cgttttggtt caacctgttg gtgaagctcg
    32401 taagtttgtc gttgctgctg aattattgac tagcttgtct gagaaatttg gctgggctga
    32461 tgttcaagtt ttggaaactt accgtggcca agaactcaac cacatcgtaa cagaacaccc
    32521 atgggataca gctgtagaag agttggtaat tcttggtgac cacgttacga ctgactctgg
    32581 tacaggtatt gtccatacag cccctggttt tggtgaggac gattacaatg ttggtattgc
    32641 taataatctt gaagtcgcag tgactgttga tgaacgtggt atcatgatga agaatgctgg
    32701 tcctgaattt gaaggtcaat tctatgaaaa ggtagttcca actgttattg aaaaacttgg
    32761 taacctcctt cttgcccaag aagaaatctc tcactcatat ccatttgact ggcgtactaa
    32821 gaaaccaatc atctggcgtg cagttccaca atggtttgcc tcagtttcta aattccgtca
    32881 agaaatcttg gacgaaattg aaaaagtgaa attccactca gaatggggta aagtccgtct
    32941 ttacaatatg atccgtgacc gtggtgactg ggttatctct cgtcaacgtg cttggggtgt
    33001 tccacttcct atcttctacg ctgaagatgg tacagctatc atggtagctg aaactattga
    33061 acacgtagct caactttttg aagaacatgg ttcaagcatt tggtgggaac gtgatgccaa
    33121 agacctcttg ccagaaggat ttactcatcc aggttcacca aacggcgagt tcaaaaaaga
    33181 aactgatatc atggacgttt ggtttgactc aggttcatca tggaatggag tggtggtaaa
    33241 ccgtcctgaa ttgacttacc cagccgacct ttacctagaa ggttctgacc aataccgtgg
    33301 ttggtttaac tcatcactta tcacatctgt tgccaaccat ggcgtagcac cttacaaaca
    33361 aatcttgtca caaggttttg cccttgatgg taaaggtgag aagatgtcta aatctcttgg
    33421 aaataccatt gctccaagcg atgttgaaaa acaattcggt gctgaaatct tgcgtctctg
    33481 ggtaacaagt gttgactcaa gcaatgacgt gcgtatctct atggatattt tgagccaagt
    33541 ttctgaaact taccgtaaga ttcgtaacac tcttcgtttc ttgattgcca atacatctga
    33601 ctttaaccca gctcaagata cagtcgctta cgatgagctt cgttcagttg ataagtacat
    33661 gacgatttgc tttaaccagc ttgtcaagac cattcgtgat gcctatgcag actttgaatt
    33721 cttgacgatc tacaaggcct tggtgaactt tatcaacgtt gacttgtcag ccttctacct
    33781 tgattttgcc aaagatgttg tttacattga aggtgccaaa tcactggaac gccgtcaaat
    33841 gcagactgtc ttctatgaca ttcttgtcaa aatcaccaaa ctcttgacac caatccttcc
    33901 tcatactgcg gaagaaattt ggtcatatct tgagtttgaa acagaagact tcgtccaatt
    33961 gtcagaatta ccagaggctc aaacttttgc taatcaagaa gaaatcttgg atacatgggc
    34021 agccttcatg gacttccgtg gacaagctca aaaagccttg gaagaagctc gtaatgcaaa
    34081 agttatcggt aaatcacttg aagcacactt gacagtttat ccaaatgaag tggtgaaaac
    34141 tctactcgaa gcagtaaaca gcaatgtagc tcaacttttg atcgtgtctg agttgaccat
    34201 cgcagaagga ccagctccgg aagctgccct tagcttcgaa gatgtagcct tcacagttga
    34261 acgtgctgct ggtgaagtat gtgaccgttg ccgtcgtatt gacccaacaa cagcagaacg
    34321 cagctaccag gcagttatct gtgaccactg tgcaagcatc gtagaagaaa actttgcgga
    34381 agcagtcgca gaaggatttg aagagaaata agattgaaaa gtctaggcaa aattcaattt
    34441 gagaagaaaa gacaactaat tttatagtct attaaacgca ttgtatcacg tttttgaaca
    34501 cctgatatga tgcgtttttt atttatttta aaaatttgcg aggtatgact ttttatactc
    34561 aacaagaatc aaagagaaac ttagcaagct aacagtagta agataaaata ggaatttgat
    34621 attagggata agattggtaa atagtgtaat atttttacaa caataaattt atatagttat
    34681 ttctggtttc tgaaaagtat tatattatat tttat
//
LOCUS       DAVLCS010000021        34209 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLCS010000021 DAVLCS010000000
VERSION     DAVLCS010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34209
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.021"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            211..2871
                     /gene="rrgA"
                     /locus_tag="VXC78_001148"
     CDS             211..2871
                     /gene="rrgA"
                     /locus_tag="VXC78_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus tip adhesin RrgA"
                     /protein_id="HEV0583241.1"
                     /translation="MKKVRKIFQKAVAGLCCISQLTAFSSIVALAETPETSPAIGKVV
                     IKETGEGGALLGDAVFELKNNTDGTTVSQRTEAQTGEAIFSNIKPGTYTLTEAQPPVG
                     YKPSTKQWTVEVEKNGRTTVQGEQVENREEALSDQYPQTGTYPDVQTPYQIIKVDGSE
                     KNGQHKALNPNPYERVIPEGTLSKRIYQVNNLDDNQYGIELTVSGKTVYEQKDKSVPL
                     DVVILLDNSNSMSNIRNKNARRAERAGEATRSLIDKITSDPENRVALVTYASTIFDGT
                     EFTVEKGVADKNGKRLNDSLFWNYDQTSFTTNTKDYSYLKLTNDKNDIVELKNKVPTE
                     AEDHDGNRLMYQFGATFTQKALMKADEILTQQARQNSQKVIFHITDGVPTMSYPINFN
                     HATFAPSYQNQLNAFFSKSPNKDGILLSDFITQATSGEHTIVRGDGQSYQMFTDKTVY
                     EKGAPAAFPVKPEKYSEMKAAGYAVIGDPINGGYIWLNWRESILAYPFNSNTAKITNH
                     GDPTRWYYNGNIAPDGYDVFTVGIGINGDPGTDEATATSFMQSISSKPENYTNVTDTT
                     KILEQLNRYFHTIVTEKKSIENGTITDPMGELIDLQLGTDGRFDPADYTLTANDGSRL
                     ENGQAVGGPQNDGGLLKNAKVLYDTTEKRIRVTGLYLGTDEKVTLTYNVRLNDEFVSN
                     KFYDTNGRTTLHPKEVEQNTVRDFPIPKIRDVRKYPEITISKEKKLGDIEFIKVNKND
                     KKPLRDAVFSLQKQHPDYPDIYGAIDQNGTYQNVRTGEDGKLTFKNLSDGKYRLFENS
                     EPAGYKPVQNKPIVAFQIVNGEVRDVTSIVPQDIPAGYEFTNDKHYITNEPIPPKREY
                     PRTGGIGMLPFYLIGCMMMGGVLLYTRKHP"
     gene            3095..5059
                     /locus_tag="VXC78_001149"
     CDS             3095..5059
                     /locus_tag="VXC78_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEV0583242.1"
                     /translation="MKSINKFLTMLAALLLTASSLFSAATVFAAEQKTKTLTVHKLLM
                     TDQELDAWNSDAITTAGYDGSQNFEQFKQLQGVPQGVTEISGVAFELQSYTGPQGKEQ
                     ENLTNDAVWTAVNKGVTTETGVKFDTEVLQGTYRLVEVRKESTYVGPNGKVLTGMKAV
                     PALITLPLVNQNGVVENAHVYPKNSEDKPTATKTFDTAAGFVDPGEKGLAIGTKVPYI
                     VTTTIPKNSTLATAFWSDEMTEGLDYNGDVVVNYNGQPLDNSHYTLEAGHNGFILKLN
                     EKGLEAINGKDAEATITLKYTATLNALAVADVPEANDVTFHYGNNPGHGNTPKPNKPK
                     NGELTITKTWADAKDAPIAGVEVTFDLVNAQTGEVVKVPGHETGIVLNQTNNWTFTAT
                     GLDNNTEYKFVERTIKGYSADYQTITETGKIAVKNWKDENPEPINPEEPRVKTYGKKF
                     VKVDQKDERLKEAQFVVKNEQGKYLALKSAAQQAVNEKAAAEAKQALDAAIAAYTNAA
                     DKNAAQAIVDAAQKTYNDNYRAARFGYVEVERKEDALVLTSNTDGQFQISGLAAGSYT
                     LEETKAPEGFAKLGDVKFEVGAGSWNQGDFNYLKDVQKNDATKVVNKKITIPQTGGIG
                     TIIFAVAGAVIMGIAVYAYVKNNKDEDQLA"
     gene            5106..6287
                     /gene="rrgC"
                     /locus_tag="VXC78_001150"
     CDS             5106..6287
                     /gene="rrgC"
                     /locus_tag="VXC78_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus minor pilin RrgC"
                     /protein_id="HEV0583243.1"
                     /translation="MISRIFFVMALCFSLVWGAHAVQAQEDHTLVLQLENYQEVVSQL
                     PSRDGHRLQVWKLDDSYSYDNRVQIVRDLHSWDENKLSSFKKTSFEMTFLENQIEVSH
                     IPNGLYYVRSIIQTDAVSYPAEFLFEMTDQTVEPLVIVAKKADTVTTKVKLIKVDQDH
                     NRLEGVGFKLVSVARDGSEKEVPLIGEYRYSSSGQVGRTLYTDKNGEIVVTNLPLGTY
                     RFKEVEPLAGYTVTTMDTDVQLVDHQLVTITVVNQKLPRGNVDFMKVDGRTNTSLQGA
                     MFKVMKEENGHYTPVLQNGKEVVVASGKDGRFRVEGLEYGTYYLWELQAPTGYVQLTS
                     PVSFTIGKDTRKELVTVVKNNKRPRIDVPDTGEETLYILMLVAILLFGSGYYLTKKTN
                     N"
     gene            6626..7528
                     /gene="srtC-1"
                     /locus_tag="VXC78_001151"
     CDS             6626..7528
                     /gene="srtC-1"
                     /locus_tag="VXC78_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-1"
                     /protein_id="HEV0583244.1"
                     /translation="MAKTKKQKRNNLLLGVVFFIGMAVMAYPLVSRLYYRVESNQQIA
                     DFDKEKATLDEADIDERMKLAQAFNDSLNNVVSGDPWSEEMKKKGRAEYARMLEIHER
                     MGHVEIPVIDVDLPVYAGTAEEVLQQGAGHLEGTSLPIGGNSTHAVITAHTGLPTAKM
                     FTDLTKLKVGDKFYVHNIKEVMAYQVDQVKVIEPTNFDDLLIVPGHDYVTLLTCTPYM
                     INTHRLLVRGHRIPYVAEVEEEFIAANKLSHLYRYLFYVAVGLIVILLWIIRRLRKKK
                     KQPEKALKALKAARKEVKVEDGQQ"
     gene            7515..8408
                     /gene="srtC-2"
                     /locus_tag="VXC78_001152"
     CDS             7515..8408
                     /gene="srtC-2"
                     /locus_tag="VXC78_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-2"
                     /protein_id="HEV0583245.1"
                     /translation="MDNSRRSRKKGTKKKKHPLILLLIFLVGFAVAIYPLVSRYYYRI
                     ESNEVIKEFDETVSQMDKAELEERWRLAQAFNATLKPSEILDPFTEQEKKKGVSEYAN
                     MLKVHERIGYVEIPAIDQEIPMYVGTSEEILQKGAGLLEGASLPVGGENTHTVVTAHR
                     GLPTAELFSQLDKMKKGDVFYLHVLDQVLAYQVDQILTVEPNDFEPVLIQHGEDYATL
                     LTCTPYMINSHRLLVRGKRIPYTAPIAERNRAVRERGQFWLWLLLAALVMILVLSYGV
                     YRHRRIVKGLEKQLEEHHVKG"
     gene            8395..9246
                     /locus_tag="VXC78_001153"
     CDS             8395..9246
                     /locus_tag="VXC78_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEV0583246.1"
                     /translation="MSKAKLQKLLGYLLMLVALVIPVYCFGQMVLQSLGQVKGHEIFS
                     ESVTADSYQEQLQRSLDYNQRLDSQNRIVDPFLAEGYEVNYQVSDDPDAVYGYLSIPS
                     LEIMEPVYLGADYHHLAMGLAHVDGTPLPVEGKGIRSVIAGHRAEPSHVFFRHLDQLK
                     VGDALYYDNGQEIVEYQMMDTEIILPSEWEKLESVSSKNIMTLITCDPIPTFNKRLLV
                     NFERVAVYQKSDPQTAAVARVAFTKEGQSVSRVATSQWLYRGLVVLAFLGILFVLWKL
                     ARLLRGK"
     gene            complement(9319..10595)
                     /locus_tag="VXC78_001154"
                     /pseudo
     CDS             complement(9319..10595)
                     /locus_tag="VXC78_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(10709..10849)
                     /locus_tag="VXC78_001155"
     CDS             complement(10709..10849)
                     /locus_tag="VXC78_001155"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583247.1"
                     /translation="MKPVFQALNKELIQENLTLTIICVGGYVLEYHGLRATQDVDAFM
                     AL"
     gene            complement(10851..11135)
                     /locus_tag="VXC78_001156"
     CDS             complement(10851..11135)
                     /locus_tag="VXC78_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583248.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(12569..13792)
                     /locus_tag="VXC78_001157"
     CDS             complement(12569..13792)
                     /locus_tag="VXC78_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0583249.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            13960..15282
                     /locus_tag="VXC78_001158"
     CDS             13960..15282
                     /locus_tag="VXC78_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0583250.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDSVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            15284..17170
                     /locus_tag="VXC78_001159"
     CDS             15284..17170
                     /locus_tag="VXC78_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV0583251.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEEKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRTLNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGENWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            17338..17682
                     /locus_tag="VXC78_001160"
     CDS             17338..17682
                     /locus_tag="VXC78_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0583252.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            17692..19104
                     /gene="lacG"
                     /locus_tag="VXC78_001161"
     CDS             17692..19104
                     /gene="lacG"
                     /locus_tag="VXC78_001161"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0583253.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            19174..20853
                     /locus_tag="VXC78_001162"
     CDS             19174..20853
                     /locus_tag="VXC78_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0583254.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSTFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            complement(20979..22418)
                     /locus_tag="VXC78_001163"
     CDS             complement(20979..22418)
                     /locus_tag="VXC78_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0583255.1"
                     /translation="MNKSMIHYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(22422..23771)
                     /gene="trkA"
                     /locus_tag="VXC78_001164"
     CDS             complement(22422..23771)
                     /gene="trkA"
                     /locus_tag="VXC78_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV0583256.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKEVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            23959..24807
                     /locus_tag="VXC78_001165"
     CDS             23959..24807
                     /locus_tag="VXC78_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV0583257.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            24822..25370
                     /locus_tag="VXC78_001166"
     CDS             24822..25370
                     /locus_tag="VXC78_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV0583258.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            25377..25625
                     /locus_tag="VXC78_001167"
     CDS             25377..25625
                     /locus_tag="VXC78_001167"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583259.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVR"
     gene            25736..27418
                     /locus_tag="VXC78_001168"
     CDS             25736..27418
                     /locus_tag="VXC78_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583260.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKKEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLRDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            27403..28233
                     /locus_tag="VXC78_001169"
     CDS             27403..28233
                     /locus_tag="VXC78_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0583261.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGAYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            28426..28929
                     /locus_tag="VXC78_001170"
     CDS             28426..28929
                     /locus_tag="VXC78_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV0583262.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFMSQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      28983..29217
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            29382..29945
                     /locus_tag="VXC78_001171"
     CDS             29382..29945
                     /locus_tag="VXC78_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0583263.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            29959..30585
                     /locus_tag="VXC78_001172"
     CDS             29959..30585
                     /locus_tag="VXC78_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0583264.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            30612..31028
                     /locus_tag="VXC78_001173"
     CDS             30612..31028
                     /locus_tag="VXC78_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583265.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFFGLKSRRRENGFQLGILHYLRIISPL"
     gene            30926..31237
                     /locus_tag="VXC78_001174"
                     /pseudo
     CDS             30926..31237
                     /locus_tag="VXC78_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            31365..31952
                     /locus_tag="VXC78_001175"
     CDS             31365..31952
                     /locus_tag="VXC78_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV0583266.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            32342..33949
                     /locus_tag="VXC78_001176"
     CDS             32342..33949
                     /locus_tag="VXC78_001176"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV0583267.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT        10441 a         5704 c         7587 g        10477 t
ORIGIN      
        1 tatacaagtg tgtcattgcc aggttgagaa gatagctata acgcactttt atacgctttt
       61 gctacgtttg ttagtgaacg gattaactca gtgagataaa ttttatcaga acataagtaa
      121 tccgtttctt cgtgtataca gattgaaagt acctatgaat catagaagga ttaacttgtt
      181 ctatgaataa tgcttaacag ggagacacac atgaaaaaag taagaaagat atttcagaag
      241 gcagttgcag gactgtgctg tatatctcag ttgacagctt tttcttcgat agttgcttta
      301 gcagaaacgc ctgaaaccag tccagcgata ggaaaagtag tgattaagga gacaggcgaa
      361 ggaggagcgc ttctaggaga tgccgtcttt gagttgaaaa acaatacgga tggcacaact
      421 gtttcgcaaa ggacagaggc gcaaacagga gaagcgatat tttcaaacat aaaacctggg
      481 acatacacct tgacagaagc ccaacctcca gttggttata aaccctctac taaacaatgg
      541 actgttgaag ttgagaagaa tggtcggacg actgtccaag gtgaacaggt agaaaatcga
      601 gaagaggctc tatctgacca gtatccacaa acagggactt atccagatgt tcaaacacct
      661 tatcagatta ttaaggtaga tggttcggaa aaaaacggac agcacaaggc gttgaatccg
      721 aatccatatg aacgtgtgat tccagaaggt acactttcaa agagaattta tcaagtgaat
      781 aatttggatg ataaccaata tggaatcgaa ttgacggtta gtgggaaaac agtgtatgaa
      841 caaaaagata agtctgtgcc gctggatgtc gttatcttgc tcgataactc aaatagtatg
      901 agtaacattc gaaacaagaa tgctcgacgt gcggaaagag ctggtgaggc gacacgttct
      961 cttattgata aaattacatc tgatccagaa aatagggtag cgcttgtgac ttatgcttcc
     1021 actatctttg atgggaccga gtttacagta gaaaaagggg tagcagataa aaacggaaaa
     1081 cgattgaatg attctctttt ttggaattat gatcagacga gttttacaac caataccaaa
     1141 gattatagtt atttaaagct gactaatgat aagaatgaca ttgtagaatt aaaaaataag
     1201 gtacctaccg aggcagaaga ccatgatgga aatagattga tgtaccaatt cggtgccact
     1261 tttactcaga aagctttgat gaaggcagat gagattttga cacaacaagc gagacaaaat
     1321 agtcaaaaag tcattttcca tattacggat ggtgtcccaa ctatgtcgta tccgattaat
     1381 tttaatcatg ctacgtttgc tccatcatat caaaatcaac taaatgcatt ttttagtaaa
     1441 tctcctaata aagatggaat actattaagt gattttatta cgcaagcaac tagtggagaa
     1501 catacaattg tacgcggaga tgggcaaagt taccagatgt ttacagataa gacagtttat
     1561 gaaaaaggtg ctcctgcagc tttcccagtt aaacctgaaa aatattctga aatgaaggcg
     1621 gctggttatg cagttatagg cgatccaatt aatggtggat atatttggct taattggaga
     1681 gagagtattc tggcttatcc gtttaattct aatactgcta aaattaccaa tcatggtgac
     1741 cctacaagat ggtactataa cgggaatatt gctcctgatg ggtatgatgt ctttacggta
     1801 ggtattggta ttaacggaga tcctggtacg gatgaagcaa cggctactag ttttatgcaa
     1861 agtatttcta gtaaacctga aaactatacc aatgttactg acacgacaaa aatattggaa
     1921 cagttgaatc gttatttcca caccatcgta actgaaaaga aatcaattga gaatggtacg
     1981 attacagatc cgatgggtga gttaattgat ttgcaattgg gcacagatgg aagatttgat
     2041 ccagcagatt acactttaac tgcaaacgat ggtagtcgct tggagaatgg acaagctgta
     2101 ggtggtccac aaaatgatgg tggtttgtta aaaaatgcaa aagtgctcta tgatacgact
     2161 gagaaaagga ttcgtgtaac aggtctgtac cttggaacgg atgaaaaagt tacgttgacc
     2221 tacaatgttc gtttgaatga tgagtttgta agcaataaat tttatgatac caatggtcga
     2281 acaaccttac atcctaagga agtagaacag aacacagtgc gcgacttccc gattcctaag
     2341 attcgtgatg tgcggaagta tccagaaatc acaatttcaa aagagaaaaa acttggtgac
     2401 attgagttta ttaaggtcaa taaaaatgat aaaaaaccac tgagagatgc ggtctttagt
     2461 cttcaaaaac aacatccgga ttatccagat atttatggag ctattgatca aaatggcact
     2521 tatcaaaatg tgagaacagg tgaagatggt aagttgacct ttaaaaatct gtcagatggg
     2581 aaatatcgat tatttgaaaa ttctgaacca gctggttata aacccgttca aaataagcct
     2641 atcgttgcct tccaaatagt aaatggagaa gtcagagatg tgacttcaat cgttccacaa
     2701 gatataccag cgggttacga gtttacgaat gataagcact atattaccaa tgaacctatt
     2761 cctccaaaga gagaatatcc tcgaactggt ggtatcggaa tgttgccatt ctatctgata
     2821 ggttgcatga tgatgggagg agttctatta tacacacgga aacatccgta aagtgtagaa
     2881 atgataatat ctatgttctg aacgatactt ttaagaagta gcactcaaga agagatttaa
     2941 gtttacttgg tgaaacctgt tttattcgta agtaaactat cattgaaagg ggagatgttt
     3001 tcgaaaactt gcacagaaaa aggattatta ttgtcatgtg taattcatta cattgctcac
     3061 agttgatttt aagagatatg aataaggaga aatcatgaaa tcaatcaaca aatttttaac
     3121 aatgcttgct gccttattac tgacagcgag tagcctgttt tcagctgcaa cagtttttgc
     3181 ggcggaacaa aaaactaaga cacttacagt tcataaatta ttgatgacag atcaagagct
     3241 tgacgcttgg aattctgatg cgattactac tgcaggttat gacggttcgc aaaattttga
     3301 acagttcaaa caacttcaag gtgttccaca aggagtaacc gaaatctctg gtgttgcatt
     3361 cgagttacag agttatacgg gtcctcaagg aaaagaacaa gaaaatttaa cgaatgatgc
     3421 ggtttggact gcggttaata aaggtgtgac gactgaaacg ggtgttaaat ttgatactga
     3481 agttttacaa gggacatatc gtcttgtcga agtacgtaaa gaatcgactt atgtcggtcc
     3541 aaatggtaaa gttttaacag gtatgaaagc tgttcctgct ttaattactc tgccgcttgt
     3601 aaaccaaaat ggtgttgtag aaaatgcaca tgtctatcca aagaattctg aagacaaacc
     3661 tacagcaacg aaaacatttg atactgcagc aggtttcgta gatccaggtg aaaaaggttt
     3721 agcaattggc actaaggtac cgtatattgt tacaacaact attccgaaaa actcaactct
     3781 tgcaacagct ttctggtcag atgaaatgac agaaggtcta gattataatg gtgatgtagt
     3841 tgttaattat aatggtcaac cgcttgataa ttctcattac acattagaag caggtcataa
     3901 tggctttatc ttgaagttaa atgaaaaagg tctggaagca atcaacggta aagatgcaga
     3961 agcaacaatt acgttgaagt atactgcaac tttaaatgct cttgctgttg ctgatgtgcc
     4021 agaagcgaat gatgtaacat tccattatgg aaacaaccca ggtcatggta acactccaaa
     4081 accaaacaaa cctaaaaacg gtgaacttac aattactaaa acatgggctg atgctaaaga
     4141 tgctcctata gcaggtgtag aagtaacttt tgatttggta aatgctcaga caggtgaggt
     4201 cgttaaagta cctggacatg aaacaggtat tgtattgaat caaacaaata attggacatt
     4261 tactgctaca ggtcttgata ataatacaga atataaattt gttgaacgga caattaaggg
     4321 atattctgca gattaccaaa caattactga aacaggaaaa attgctgtta aaaactggaa
     4381 agatgaaaat ccagaaccaa taaatcctga agagccacgt gtaaaaacat atggtaaaaa
     4441 attcgttaag gttgaccaaa aagacgaacg cttaaaagaa gcacaattcg ttgtgaagaa
     4501 tgagcaaggg aaatatcttg cactcaaatc tgcagcacaa caagctgtaa atgagaaagc
     4561 tgccgcagaa gcgaaacaag cgctagatgc agcgatagca gcctatacaa atgctgcaga
     4621 taaaaatgca gcacaagcta tagtagatgc tgcgcaaaaa acatataatg acaattacag
     4681 agcagctaga tttggctatg tagaagtaga gagaaaagaa gatgcgttag ttcttacttc
     4741 taacactgat ggtcaattcc aaatttcagg tcttgctgct ggaagctaca cgttggaaga
     4801 aacaaaagct ccagaaggct ttgcaaaact tggagatgtg aagtttgagg ttggagcagg
     4861 ttcttggaat caaggtgatt tcaattattt aaaagatgtt cagaagaacg acgctacaaa
     4921 agtagtcaac aaaaaaatca cgatccctca aacgggtggt attggtacaa ttatctttgc
     4981 tgtagcgggg gctgtgatta tgggtattgc agtgtacgca tatgttaaaa acaacaaaga
     5041 tgaggatcaa cttgcttaag taagagagaa aggagccatt gatgacaatg cagaaaatgc
     5101 agaaaatgat tagtcgtatc ttctttgtta tggctctgtg tttttctctt gtatggggtg
     5161 cacatgcagt ccaagcgcaa gaagatcaca cgttggtctt gcaattggag aactatcagg
     5221 aggtggttag tcaattgcca tctcgtgatg gtcatcggtt gcaggtatgg aagttggatg
     5281 attcgtattc ctatgataat cgggtgcaaa ttgtgagaga cttgcattcg tgggatgaga
     5341 ataaactttc ttctttcaaa aagacttcgt ttgagatgac cttccttgag aatcagattg
     5401 aagtatctca tattccaaat ggtctttact atgttcgctc tattatccag acggatgcgg
     5461 tttcttatcc agctgaattt ctttttgaaa tgacagatca gacggtagag cctttggtca
     5521 ttgtagcgaa aaaagcagat acggtgacaa caaaggtgaa gctgataaag gtggatcaag
     5581 accacaatcg cttggagggt gtcggcttta aattggtatc agtagcaaga gatggttctg
     5641 aaaaagaggt tcccttgatt ggagaatacc gttacagttc ttctggtcaa gtaggtagaa
     5701 ctctctatac tgataaaaat ggagagattg ttgtgacaaa tcttcctctt gggacctatc
     5761 gtttcaagga ggtggagcca ctggcaggct atactgttac gacgatggat acggatgtcc
     5821 agttggtaga tcatcagctg gtgacgatta cggttgtcaa tcagaaatta ccacgtggca
     5881 atgttgactt tatgaaggtg gatggtagga ccaatacctc tcttcaaggg gcaatgttca
     5941 aagtcatgaa agaagaaaac ggacactata ctcctgttct tcaaaatggt aaggaagtag
     6001 ttgtggcatc agggaaagat ggtcgtttcc gagtggaagg tctagagtat gggacatatt
     6061 atttatggga gctccaagct ccaactggtt atgttcaatt aacatcgcct gtttccttta
     6121 caatcgggaa agatactcgt aaggaactgg taacagtggt taaaaataac aagcgaccac
     6181 ggattgatgt gccagataca ggggaagaaa ccttgtatat cttgatgctt gttgccattt
     6241 tgttgtttgg tagtggctat tatcttacga aaaaaacaaa taactgatat tcaatgtaca
     6301 tcattatgaa aaagatagca ggctgaaggg aagaccagag tactctgagg tgatgttaat
     6361 caggaatcat ggtgatttgg catgaatcac aataacggat atgaggctgg gcagattgtg
     6421 ccagcctcat tgtgggttat tgtttgtaaa acgataggac tggtctggta atcattttag
     6481 gaatggacag gactgggatt ctgatttaaa atggatggtg aatcagaaag aaatgagatt
     6541 ttctcgtttc tcttagcaga taggattgtc tgttaggaaa agcgataaaa tgatgagttt
     6601 gaagttaaag gaatgctgat aaaaaatggc aaaaacaaaa aagcaaaaac gaaacaatct
     6661 cctattagga gtggtatttt tcattggaat ggcggtaatg gcgtatccgc tggtgtctcg
     6721 cttgtattat cgagtggaat caaatcaaca aattgctgac tttgataagg aaaaagcaac
     6781 gttggatgag gctgacattg atgaacgaat gaaattggca caagccttca atgactcttt
     6841 gaataatgta gtgagtggcg atccttggtc ggaagaaatg aagaaaaaag ggcgagcaga
     6901 gtatgcacgt atgttagaaa tccatgagcg gatggggcat gtggaaatcc ccgttattga
     6961 cgtggatttg ccggtttatg ctggtactgc tgaagaggta ttgcagcaag gggctgggca
     7021 tctagaggga acttctctgc cgatcggagg caattcgacc catgcggtga ttacggcaca
     7081 tacaggtttg ccaacagcta agatgtttac ggatttgacc aaacttaaag ttggggataa
     7141 gttttatgtg cacaatatca aggaagtgat ggcctatcaa gtggatcaag taaaggtgat
     7201 tgagccgacg aactttgatg atttattgat tgtaccaggt catgattatg tgaccttgct
     7261 gacttgtacg ccatacatga tcaataccca tcgtctattg gttcgggggc atcggatacc
     7321 gtacgtagca gaggttgagg aagaatttat tgcagcaaac aaactcagtc atctctatcg
     7381 ctacctgttt tatgtggcag ttggtttgat tgtgattctt ttatggatta ttcgacgctt
     7441 gcgcaagaag aaaaaacaac cggaaaaggc tttgaaggcg ctgaaagcag caaggaagga
     7501 agtgaaggtg gaggatggac aacagtagac gttcacgaaa aaaaggcaca aaaaagaaga
     7561 aacatccgct gatccttctt ctgattttct tagtaggatt cgccgttgcg atatatccat
     7621 tggtgtctcg ttattattat cgtattgagt caaacgaggt tattaaagag tttgatgaga
     7681 cggtttccca gatggataag gcagaacttg aggagcgttg gcgcttggct caagccttca
     7741 atgcgacctt gaaaccatct gaaattcttg atccttttac agagcaagag aaaaagaaag
     7801 gcgtctcaga atatgccaat atgctaaagg tccatgagcg gattggctat gtggaaattc
     7861 ctgcgattga tcaggaaatt ccgatgtatg tcggaacgag tgaggaaatt cttcagaagg
     7921 gcgcaggatt gctagaggga gcttcgttac cggttggtgg tgaaaatacc cacacagttg
     7981 tcactgctca tagaggatta ccgacggcag aactgtttag tcaattggat aagatgaaaa
     8041 aaggggatgt cttttatctt cacgttttag accaggtgtt ggcctaccaa gtggatcaga
     8101 ttttgacggt tgagccaaat gactttgagc ctgtcttgat tcaacatggg gaagattatg
     8161 cgaccttgtt gacctgtaca ccgtatatga ttaacagtca tcgtctgttg gtacgtggga
     8221 agcggattcc gtatacggca ccaattgcag agcgaaatcg agcggtgaga gagcgtgggc
     8281 aattctggtt gtggttattg ctagcggcgt tggttatgat tctggtattg agttacgggg
     8341 tgtatcgtca tcgtcgcatt gtcaaagggc tagaaaaaca attggaggag catcatgtca
     8401 aaggctaagc tacagaaatt actagggtat ttgctgatgc tggtagcatt ggtgattcct
     8461 gtttattgtt ttgggcagat ggtgttacag tctttaggac aagtaaaagg tcatgagata
     8521 ttttcagaat ctgtgacggc cgacagttac caagagcaat tgcaacggtc gcttgattac
     8581 aatcaacgct tggattcgca aaatcgtatt gtagatcctt ttttggcgga agggtatgag
     8641 gtaaattacc aagtgtctga cgatcctgat gcagtctacg gctatttgtc gattccgagt
     8701 ttggaaatca tggagccagt ttatctagga gcggattacc atcatttagc aatggggttg
     8761 gcccatgtgg atgggacgcc tcttcctgtt gagggaaaag ggattcgttc agtgattgct
     8821 gggcaccgtg cagaaccaag ccatgtcttt ttccgccatt tggatcagct aaaagttgga
     8881 gatgctcttt attatgataa tggccaggaa attgtagaat atcagatgat ggacacagag
     8941 attattttac cgtcggaatg ggaaaaatta gaatcggtta gctctaaaaa tatcatgacc
     9001 ttgataacct gcgatccgat tcctaccttt aataaacgct tattagtgaa ttttgaacga
     9061 gtcgctgttt atcaaaaatc agatccacaa acagctgcag ttgcgagggt tgcttttacg
     9121 aaagaaggac aatctgtatc gcgtgttgca acctctcaat ggttgtaccg tgggctagtg
     9181 gtactggcat ttctgggaat cctgtttgtt ttgtggaagc tagcacgttt actacgaggg
     9241 aaataaaaag aaatgaaagg aaagctaagg ctgttccttt ttccggctct ttgtcaactg
     9301 tagtgggttg aaaaaaagct aagctcgaga aaggacaaat tttgtccttt cttttttgat
     9361 attcagagcg ataaaaatcc gttttttgaa gttttcaaag tttcgaaaac caaaggcatt
     9421 gcgcttgata agtttgatga gattattggt cgcttccagt ttggcattag aatagtgtag
     9481 ttgaagggcg ttgataatct tttctttatc tttgaggaag gttttaaaga cagtctgaaa
     9541 aataggatga acctgcttaa gattgtcctc aataagtccg aaaaatttct ctggttcctt
     9601 attctggaag tgaaacagca agagctgata gagctgatag tggtgtttca agtcttgtga
     9661 atggctcaaa agcttgtcta aaatctcttt attggttaag tgcatacgaa aagtaggacg
     9721 ataaaatcgc ttatcactca gtctacggct atcctgttga atgagtttcc agtagcgctt
     9781 gatagccttg tattcatggg attttcgatg aaactgattc atgatttgga catgcacacg
     9841 actcatagca cggctaagat gttgtacaat gtgaaagcga tcaagaacga ttttagcaca
     9901 cgggaaaagt tgtctagcta agtcatagta aggactaaac atatccatag taatgatttt
     9961 gacgcgacat cggacggctc tatcatattt aagaaagtga tctcggatga cagcttgtgt
    10021 tctaccttca agaacagtga tgatatcgag cttttcaaaa tcttgcgcaa taaagctcat
    10081 ctccatctcc cgattgaaac agtcactccc cggactgttt caacgtccca ggacataatc
    10141 tcaggaagac gcgaaaaatc atgctcaaag tgagaatcat tgagcttgcg aatgacagtt
    10201 gaagttgaaa tggccagctg atgagcaata tcggtcatag aaatcttctc aatcaacttt
    10261 tgcgcaattt tttggttgat aatacgagga atttgatgat tcttcttgac gatagaagtt
    10321 tcagcgacca tcatttttga acagtgatag cacttgaaac ggcgttttct aaggagaatt
    10381 ctagaaggca taccagttgt ttcgaggtaa gggatcttag acggtttttg aaagtcatat
    10441 ttcttcaatt ggtttccgca ctcagggcaa gatggggcgt cgtagtccag tttggcgatg
    10501 atttccttgt gtgtatcctt attgatgatg tctaaaatct ggatattagg gtctttaatg
    10561 tctagtaatt ttgtgataaa atgtaattgt tccatatgat tctttctaat gagttgtttt
    10621 gtcgcttttc attataggtc atatgggact tttttctaca caaaaatagg ctccataata
    10681 tccatagggg atttacccac tacaaatatt atagagccat aaaagcatca acatcttgtg
    10741 tggcacgtaa accatgatat tctaagacat aaccaccgac acagataatt gttaaagtca
    10801 gattttcctg aattaattcc ttatttaggg cttggaagac cggtttcatt ttatccatgt
    10861 ttgtatttct ccatcaattt ttgaacattg gttaacttag caggtttatt taatgaaatc
    10921 acatatttat gagttggagt atgctcttga aaggcatact tcaagctaat tttttgaaaa
    10981 cgggttagtt ctttggagtc tagcaacttt tctacatctt ggtttgttaa ataagaatag
    11041 tcttcaaaaa taacttttcg caaatagcga aaccaatggc ttgcgttgaa ttgtgattgt
    11101 ttggatgcct gtatcatata atcgtaccaa tccattgtct tcctcctata aaatttagtt
    11161 tatattattg tagtttatat tcaaaaatgt agtttttctt aattagctcg tatctatagg
    11221 atgatactga aaatcttctt gttgctttaa atcacaatcg aaaaattctg tttttcatct
    11281 tagaaaagaa tgtttagaaa tgtaaaatga accttttttc ttatccgaaa accttactaa
    11341 agtatataat ttaggaagtc aatcctgtat gataatgttt gtactatcgt cgagtttttg
    11401 cttgattgcc taacgagata aattttagaa gaattttcgg tgtgatttga caagcttctg
    11461 actggaagga tagttacact agtattgttt attaaaatga gcagatagag aaaatttgga
    11521 atctatttgc ttattatcaa tcgttttttt agcttatttg tcttagattg gtatagaact
    11581 gagctatgga ttaatactct tgtatcttat cctgttccta aatatgttgg tagaaaaatg
    11641 aagcagttgt tacgagtgtc tgtattggaa aaaattttgt ctatagaatt ctttaaatga
    11701 tatgaaggct aggaatgcca aagcactgac atatttcgtt tgaatctcat ccgctctctt
    11761 tacttgtatt tgtagaaatg ctatcagtaa tatattcgcg aacactatga tttacaacag
    11821 tgtggtcgta catctttgta actttattat acaacaacca tttacaggtg taaagttgag
    11881 cagtgtcttt agtaaattta gggatttgtt ttgtcatagt tttgatacct gtattcgttg
    11941 tttcatgagc atttgacgtt tcttttcatg taggcatttc aacaattaga atgatatttt
    12001 tccgaggatg aacttatata ttgtgacttt ttagagttat gatgcctctt gatttgacta
    12061 tcgctatcaa tttcatccac ttttacagtt tcatggtttt atgaaccgaa acatctaggt
    12121 acaggtttta gcatcaattg attgtttttg agccatatga agttgaaacg tggagatgct
    12181 tttcttgtga taacgcccta ttcaaagagg aataaccgtt tttggagaga gttcagtact
    12241 atgtggcgct aaatactata tgtaaaacat atattaaaca agatttaact aaggagaatt
    12301 gtaaaaacaa aaatgagaat ttcatataaa gtttattcta ggagtatgta tcttgaataa
    12361 aaattgttat ttaagttctg ggggttatga tgaatgtttt tataataata aaatgcagct
    12421 agaagaaaag ttattttaat ataaatcact caacatagcg agaaggcggt ttcctatatg
    12481 gaagtcgtct tgttttcata ttgtctaaat acgagatatc tactacaggt tatagttgat
    12541 ttaaacaggt ctatagattt ctaatatatt aaggtgaaat aatatcttgt aatacattgc
    12601 tatgttctat gaaaaaagcg acgatagcta atgcacaagc tcctatactt ccacgatgtt
    12661 tgttgtaagg taaaatttca atttctatat tacgagtaaa gggaacgaag tggagctggt
    12721 cttggatttt atccctgact tcatgagtga aaggttgata attaagcaat tgactgttga
    12781 tatagatttt atcagcagga ttgatgagga ggagatttgc aatagaagtg gctaataaat
    12841 tgactccttt atcaatttgt tgacgtaaag cggagtcgcc taaattataa gccgttaaaa
    12901 gggtgtctaa atgaatgtct ttttcagtct ttacaaggct ttttagtaca gttagttggg
    12961 aatttttaaa taataattgg gcgtgtttga ttaaccaagc atccgaaata tatgtttgta
    13021 aacaaccttt ttttccgcat tcacaatatt gcccattcaa ttcgacaatg gtgtgtccaa
    13081 tttctccgat ataaggattt ttagaggctc ctattttttc ttttgtgaaa aaggaagtgt
    13141 aaatacctaa tccagcgtgt aggaaaataa agttatcggg ggtattgtgt ggattaaaaa
    13201 ggtattgtcc tatagccata caatcgatat tattttttac aataaaagga aaattgaatc
    13261 ttttaattac atttaataaa ttaaaagatt cccatatggg gttgtttgta atgatacttc
    13321 cggagtcttt gttataatgt ccaggtattg ataagccaaa tccaagtaat tttgtttcca
    13381 aagggacgta ctctatagct gtttttatca tattggtaat ggtggaattg atttctgaaa
    13441 taggataatc ttcattcaaa atttctgtct cgaaaagagt tttcccttgt aagtcacata
    13501 gactgagaaa gatacctagg acgtttattt caatacctcc aacaacatac ggaatattat
    13561 ctgtgataga aatagttttt ctacgtcttc cagatccgga aaactcgcta aattcatcac
    13621 cagtttcgta tatgagggac tgttcgctta gctcttttat gatgttagtc gttgttgctg
    13681 gagtaagtcc tgtttcatta acaatatctg tacgggatgt tgctggattt cgatatagaa
    13741 actccagtat agtggctcta ttttgtaaaa aggctgattg ttttgtaatc atttgtttcc
    13801 tcctttggtt tattttatat taaacataag aaaaaatcaa ttaaaattat tattctatac
    13861 aaagaaaaaa atattgtaaa aacaacaaaa aatatattga caacgctttc tgttagtggt
    13921 atatttaatt tataaaaaat aaaaaaagga gttccggtga tgaacaatat tttagcgttt
    13981 ttagaaacaa aagtcgctcc gtttggtgaa aaagttggca accaacggca tttgaaagct
    14041 attcgtgaag gatttatgat ggcaatgcct ttgattttag tcggatcttt atttcttatt
    14101 ctaatcagtt ggcctcaaga ggattttaca aattggctga atagtgttgg attgctaagt
    14161 atcttgacaa ctatgaatca gtcaacagta gcgattatct ccttggtcgc ttgtttcggt
    14221 attgcctaca ggttgtcgga aggatatggt acagatggtc cgtcggcagg gatcatagcc
    14281 ttatccagtt ttgtattgat ggcacctcgt ttttcgagta tggtttatga taaaaatggg
    14341 gagcaggtca agcagttatt tggcggcgca ataccatttt ctagcctgaa tgcatcttct
    14401 ttgtttatgg cgattactat tggattggtt acagcagaga tttatcgtat gtttatccag
    14461 cgcggaatta cgataaaaat gccaagtggt gtcccagatg tggtaagtaa atcattttca
    14521 gctcttttac ctggctttac tacttttgtt ttgtgggctt tggtcttaaa aggtcttgaa
    14581 gcggcaggag ttgcaggagg tctcaacgga ctcctaggtg caattgttgg aacaccgctt
    14641 aagttaattg caggaacgct tccaggtatg attctatgtg ttattgtaaa ctcattcttt
    14701 tggttctgtg gagttaatgg gggacaagtt ttaaatgctt ttgtagactc agtttggtta
    14761 caatttacta cagaaaacca agaagctgtg gctgcaggac aaacactcca acacattatt
    14821 acattaccgt ttaaagattt atttgtattt attggtggcg gtggagcgac tattggtctt
    14881 gcgatttgtc tcttcctatt tagtaagagt cgtgcgaata aaacattagg taagctagct
    14941 attataccgt ctatttttaa tatcaataca gctattctat ttacgtttcc aacagtttta
    15001 aatccgatta tgctgattcc gtttattgct actcctacaa tcaatgcctt gattacctat
    15061 gtatcaatgg ctgtaggatt agtaccctat acaacaggtg taatccttcc gtggacaatg
    15121 ccaccgatta taggaggctt ccttgcaaca ggggctagtt ggcgaggagc tctattacaa
    15181 gttgttttga ttttggtttc tgtagcaatt tattatccat tcttcaaaat tgcagataaa
    15241 cgcaatcttg aaaaagaaaa agctactgtt ggagggaaat aagatggtta tcagagtatt
    15301 tgatcaacag aaaaatactt attctagctt tgccttagag gaattaagtt actatatgaa
    15361 tcgggtcttt aagactaaca tagagcttgt cgaggagaag gaagcggata tttttgtagg
    15421 attagtcaat aaagaggaca gaaaagacca tgttcttatc tcattagaca agggtaaggg
    15481 gagaattgag tctaatacaa ttgtaggttt acttattgga atttaccgaa tgtttcatga
    15541 atttggggtt gtgtatacta gaccagggcg cagacatgac tttgttccag agttacgatt
    15601 tgaagatttt ttagataaac agctatctat agatgaaaca gccagttact atcatagggg
    15661 agtatgtata gagggagcgg attcatttga aaatatacta gatttcattg attggctacc
    15721 taagattggg atgaacagtt ttttcatcca gtttgaaaat ccttactctt ttttgaaacg
    15781 ttggtatgaa catgagttta atccatacct aaataaagaa aaattctcaa atgaattagt
    15841 acaagaattg agtgataggt tggataaaga attgcaaaaa agaggtctta ttcatcatcg
    15901 tgttggtcat ggatggacag gtgaggtttt aggttactct tcaaaatttg gctgggaatc
    15961 aggtcttagt atttcagagg aggagaaacc gtatgtcgct gaaataaacg ggaaacgaga
    16021 attatttaat acggctccga ttttaaccag tctggatttt tcaaatccag atgtggcgga
    16081 taagatggta gaaattatca aggattatgc caagaaaaga cctgatgtta actacttaca
    16141 tgtatggttg tcggatgctc gtaataatat ttgtgaatgc gaaaactgta gacaagaatt
    16201 ggtttcggat cagtatattc gtactctcaa tcaattggat agggctttaa cgagtgaggg
    16261 attagataca aagatttgtt ttctgcttta ccatgagttg ctatgggcgc ctcagaaaga
    16321 aaaattagat aatcctgaac gctttaccat gatgtttgca ccgattacaa gaacatttga
    16381 aatgagttat gcagatgtag attttgacaa ttccatacct acgcctaaac cttatctgcg
    16441 taataaaatt atacttccga attctcttga ggaaaattta tcttatcttt ttgagtggca
    16501 aaaaacattt aaaggagata gtttcgtata tgactatcct ttagggcgtg ctcattatgg
    16561 cgatttaggc tatatgaaaa ttagtcaaac catttacaga gatgtatctt atctttctaa
    16621 cctacatttg aacggttaca tttcgtgtca agaattacgt gccggattcc ctcataattt
    16681 tcctaattat gttatggggg aaatgctctg gaagaagaca agaagttatg aagaattgat
    16741 tgaagaatac ttttctgctt tgtatgggga aaattggcag tctgttgttg aatatttaga
    16801 aaaattatcc agttattcct catgtgatta ttttaatgca attggcagtc gtcaaaatga
    16861 tgttttagcg aatcattatt atatagctta caatctagct gataattttt tgccaattat
    16921 tgaggaaaat atttctaagt tattaaatag tcaaaaggat gaatggaaac agctcagtta
    16981 tcatcgtgaa tatgttgtta agatggcgaa ggctttatat cttcaagcaa ccggaaaaac
    17041 aaggcaagct caagatgaat ggagaaatgt gttgaattat atccgtgggc acgaactgct
    17101 attccaatct aatttggatg tttatcgtgt aattgaagta gcaaaaaatt acgctggttt
    17161 ccacttataa atcataagta tagaaaatga accaaggtat tcagagaaga ttgatcctaa
    17221 atattatgaa atttaaggat ttttaagata tttagggtcg actttctatt tatatcgtag
    17281 cgaagtcatt ttaataatga tgtgtaaaag atggatcaag attgaggagg aagaaagatg
    17341 aaatcaaaag aagaaataaa tatgcttggt tttacaattg tcgcttacgc aggagatgca
    17401 aggtcagatt tgatggatgc tttggcgttt gcgagagatg gatattttga acaggcaaga
    17461 gaattggttg agtctgcaaa cgactcaata gtgtctgccc atcgagaaca gactaattta
    17521 ttagcggagg aggcatctgg agataatttt gaagtgagtt ttatcatgat tcatggtcaa
    17581 gatactttga tgacaacgat gctattgtat gatcaggtca agttttttat tgatgaatat
    17641 gaacgaattc gaaagattga agaacatatt ggtttgcaat gaggattagt catggaaaat
    17701 ttacaggtta aagccttacc gaaggagttt ttattaggag ctgctaccgc tgcttatcaa
    17761 gtagagggtg caactagggt agatggcaaa ggaacaaata tgtgggatgt ttatttgcaa
    17821 gaaaacagtc cgttcttacc agatccagct agtgattttt attatcgtta cgaagaggat
    17881 atagctttgg cggcagaaca tggtttgcag gctttgcgtt tatctatttc ttgggttcgt
    17941 atatttcctg atatagatgg ggagcctaat atattagctg ttcgttatta ccatagagtc
    18001 tttcagtctt gcttaaaaca taatgtgatt ccgtttgttt ctttacatca ttttgattcg
    18061 cctcagaaaa tgttagaaac aggggattgg ttgaatagag agaatattga tcgtttcata
    18121 cgatatgctc gcttttgttt ccaagaattt acagaagtca agcattggtt tacaatcaat
    18181 gaactgatgt ctcttgctgc aggtcaatat ataggaggtc agtttcctcc aaatcatcat
    18241 tttcaattat ctgaagcaat tcaagcgaat cataatatgt tgttggcgca tgctcttgca
    18301 gtcctcgaat ttcatcaatt agggattgag ggaaagatag gttgtattca tgctttaaag
    18361 ccaggctatc ctattgatgg gcaaaaagaa aatattttag cagctaaacg gtatgatgtt
    18421 tataataata aatttctatt agatggaact tttttgggct actacagtga tgacacgctt
    18481 tttcacttga atcaaatatt ggaagctaat aattctagct ttattattga agatggtgat
    18541 ttagaaatta tgaaaagagc tgcacctctt aatacgatgt ttgggatgaa ttattatcgt
    18601 tcagaattta ttcgtgaata caaaggtgaa aatagacaag aatttaattc aacaggaata
    18661 aaaggacagt cttcttttaa attaaatgct ctaggtgaat ttgtaaaaaa gcctggtatt
    18721 ccgacaacag attgggattg gaatatttat cctcaagggt tatttgatat gttgcttcgt
    18781 atcaaagaag aatatcctca acatccggtc atttatttaa ctgaaaatgg tacagccctt
    18841 aaagaggtta agccagaggg cgagaatgat attattgatg acagtaaaag aatccgttat
    18901 attgagcaac atttacacaa agttttagag gctcgagata ggggagtcaa tattcaaggc
    18961 tattttatat ggtctttgca agatcaattt tcttgggcga atggctacaa taagcgatat
    19021 ggtcttttct ttgttgatta tgaaacacag aagagatata ttaagaaaag tgctctttgg
    19081 gtaaaaggat taaaacggaa ttaaggttag cgatttgact gatgtttaat atattttaac
    19141 tatgagctta aattttttac aggaggagtt tttatggata agttagtcgc tgccattgaa
    19201 aagcaacaag ggaaatttga aaaaatttct actaataatt atatgatggc tattaaagat
    19261 ggatttattg ctactatgcc tttaattatg ttttcaagct ttttgatgat tattattatg
    19321 attcctaaaa atttcggagt agagttaccg agtccagcta ttgcctggat gaggaaagtg
    19381 tatatgctaa ccatgggagt tttgggtgtt attgtttcag ggacagttgc aaagtcattg
    19441 gctggaaatg ttaatagaaa aatgcctcct ggaaaggtaa taaatgatac ttctgcaatg
    19501 ttggcggcca tatgtggcta tcttgtatta actgtaacgc ttgtagttga tgagaaaacg
    19561 ggatctacaa gtttgtcgac aaactattta ggatctcaag gattgataac ttcgtttgtc
    19621 agtaccttta ttactgtaaa tgtttaccga ttctgtatta agcgagacat tactattcat
    19681 ttacctaagg aagttcctgg ggctatatca caagctttta gagatatttt tcctttttct
    19741 tttgttttac ttattagtgg tttgttagat attgtatctc ggtttagttt agatgttcct
    19801 tttgcccaag tatttcaaca actattgact cctattttta agggggcaga atcatatcct
    19861 gctatgatgt tgatttggtt tatgtgcgct ttgctttggt ttgttggaat tcatggacca
    19921 tctattgtct tacctgctgt tacagcttta caactgagca atatggaaga gaatgctcaa
    19981 cttcttgcaa atgggcagtt tccttatcat tctttaacgc ctaatttcgg aaattatatc
    20041 gctgctatcg gaggaacggg ggctaccttt gttgtaccat ttattttgat tttctttatg
    20101 cggtctaaac aattaaaatc ggtaggtaaa gctacaatta ctcctgtttt atttgcggtg
    20161 aatgaacctc ttctatttgg tatgccagtt attttgaatc cctatctttt tgtacctttt
    20221 ttgatgactc caccagtgaa tgtatttcta ggaaaggtct ttattgattt ctttggaatg
    20281 aatggatttt atatccagtt accttgggcc tttcctggtc ccttgggatt gttaattgga
    20341 acgaattttc aatctatctc ctttgtattt ttatctttga ttttagttgt cgacatattg
    20401 atttatttgc cattctgtag agcgtatgat agacagttac tgatgaaaga agatgttgca
    20461 agctcaaatg atattatttt agaggaggag acaagtgaaa taatgcctgg tgagttagat
    20521 gaaataaaaa gtaaggagtt gaaagtactg gttctttgtg cagggtctgg aacaagtgcg
    20581 caattagcca atgcaattaa cgagggcgct caattagcag aagttagagt gattgcgaat
    20641 tcaggagcgt acggagctca ttatgatatt atgggtgttt atgatttaat tattctggct
    20701 ccacaagttc ggagttatta tagagagatg aaggtggatg cagaaagatt aggtattcag
    20761 atagttgcta ccagaggaat ggaatatatt catttaacaa agagtccaag taaatcctta
    20821 caatttgtat tggagcatta ccaagctgtg tagtaagttt ttccatcttt tatttgagta
    20881 aggattttgc ttacagatag gcttggattt aaaaacgttc cccctttttt aatataagaa
    20941 tccctctttc acaattgtaa aaagagggat tttgtatttt atctcttaga ccaagttctc
    21001 ttcataaaga gaaggaggat tgggtaaatc tccaagcgcc ctgcaatcat tgcaaaggat
    21061 aggagaattt ttgagatggg actaaagatt gagaaactag aagtggttcc tagaataggc
    21121 ccgatattat tgaaacagct aaagacagcg ctggtcacga ccagaaaatc attgctatct
    21181 aggctgacaa taaagataag cgctagcaaa atcatagcat agatgacaaa gtacttgaga
    21241 atcttatgct gggtatcttt atcaatcacc gtttgattca catggagggt caaaacacgg
    21301 tggggcgata ggattgacaa aatttggttt ttggcaattt ttgaaaggat gaggcctcga
    21361 ataatcttga gtccacctgc agttgatcca gcagagccac cgattgccat gaggaaaagg
    21421 aggataaact gggagaagag gggccagttg gtaatatctc catatccaaa accagttgtt
    21481 gtaatgatgt tggaaacctg gaagaaggtc atttcaaagc tctttgaaaa ccctgggtag
    21541 aggtagaggg tgttgaggct aatcaagcct gtagaaacca gtacaatgac caagtaagcc
    21601 cgaagttctt cgtcaccaaa gaaggccttg atgcgacgga gcatgaggta gtagtagagg
    21661 ttgaaattta ccccaaaaac cagaactccg atactgacca gataggtaat cagtgagctg
    21721 ccatagtggg caattccgtc gttatagacg gtaaagcctc cagttcccgc tgtccccata
    21781 gcaatgacaa aactatcgta gagaggcata ccagctagat aatagatgat gacaaagagg
    21841 gagaagagag ctagataaag gagatagaga atctgggcag tgttttttag tttggataca
    21901 accttgccaa aaacaggacc tggaacctca gccttcatca cctctaggtg gctatttttg
    21961 gcattgtcca taatagcaag tgcaaaaaca agcactccca tccctccaat caagtgggta
    22021 aaacttcgcc agaagaggag ggaacggctg agaaccgaaa cgtcgttcaa aatacttgct
    22081 ccagtagttg taaacccaga actaatttca aaaaaggcat caataaggct ggggatttgc
    22141 ccagaaaaga caaaggggag accaccaaag aaagaccaaa ggatccaaca gagggcaacg
    22201 atcaagactc cctccttggc ataaatccgt tgattttttg gcttctgtaa actccctgaa
    22261 ccgcctaaca atacgagaat ccctatggtt gaaaagaggg ctgtaaagac ttggctcgat
    22321 tcacggtaat agacagcgat agccacagga accaagagga gaacagcttc aatcaaaagt
    22381 aactttgaaa ggaggtaatg aatcatactt ttattcattt cttacctcgc aatcaagtca
    22441 taaatcttgg tgatgtttgg caacaaggtt gttactagga gcttgtctcc aacttccaac
    22501 atatcctccc cagttgggaa aatagtcttg ccctttcgaa taatggctgc aataagaacc
    22561 tcttttttca atttcagttg agaaagaggt ttggcagtca ttttattggc ttccttgata
    22621 tggaattgca gggtttcgat ttggccattg gctagatggt gcatggcttg aaggtctgaa
    22681 tactgggcat taactcgacc acgaataaag tgcataatcg tatctacagc gatgctttta
    22741 ggtgtgatga tacttgaaaa atcaggcgca ttgataatct cgaggagact ggtacgattg
    22801 accttagtaa tatttttctg tacacctacc ctgtcaagga acatagatgt aatcagattt
    22861 tcctcatcga ctcctgttag agtcgcaacg gcatcatagt gttgagcact ttcttccagc
    22921 aggatatctt ttgcggttcc atctccttga acgatgtaga gatttgggaa tttctcgcta
    22981 aagaagctgg cgatttcagg attgatttca atgacttttg tatcgatacg actatctttg
    23041 agaataccaa gtagataata ggcaattcta cctgctccaa cgatgagaag gctcttcacg
    23101 gcgcgtgatt taaaataatt atggaagagt atcatatcga cacggttacc agtgacaaag
    23161 attctatctt tatcctgtac agtcatgtca ccgcttggaa tgataatttg atgatccctc
    23221 tctatcgcac agacaatgac attaccaaat tttttacgaa aatcagaaat gggcatttgg
    23281 caaagaccgc tggtggactt gacgacaaat tccatgaggc taacgcgtcc accagcaaag
    23341 cgttcgacag acagggcgtt ggggaagtca atgatattcg cgatagcgcg ggcagccaag
    23401 agctcaggat taacgataag agaaaaaccg agaatattct tttccttgaa ataagagtta
    23461 gaatattcag ggttccgcac ccgaacgata gtttctttag ctcccatttt cttggctaga
    23521 actgctgcaa tcatgttgac ttcatcgtgc tcagtcaggg cgataaagat atcacaatct
    23581 tggacgctgg cttgctcaag aatggcaaaa tcggccccgt taccaaggat accaatgata
    23641 tcaaagcgac tgacaatatg attgagaaca gcttcgtctt gctcaatcag caaaacatca
    23701 tgcttttctg caaccaagga gcgacagagg gcaaaaccaa cttttccccc tccgacaagg
    23761 ataattttca taataaaacc tactttttca tgatgtaact atcataccct ttttcaagaa
    23821 aaaatgcacc tactagctaa taacaagagc ttttagtgaa aattcgctat aaggtaaaac
    23881 tataccctaa ccaattgaaa tagctattag cgactttctc tgaaatatgg tatgataaag
    23941 gatatacaag gagataaaat gaacaataat ttactggtat tacaatcaga ctttggtctg
    24001 gttgatggtg cggtgtcggc tatgattgga gtggctttag aagagtctcc aaccttaaaa
    24061 atccatcact tgacgcacga tatcacgcct tataatattt ttgaggggag ctatcgtctc
    24121 tttcagacgg tggattactg gcctgaggga acgacgtttg tatcggttgt cgatccaggt
    24181 gtcggttcga aacgtaagag tgtagttgcc aagactgcaa aaaatcaata cattgtcacg
    24241 ccagataatg ggacgctttc ctttatcaag aaacacgttg gcattgtagc cattcgtgag
    24301 atttctgagg tggccaatag gcgtcaaaac acagagcatt cttatacctt ccacggtcgt
    24361 gatgtctatg cctatactgg tgctaaactg gccagtggtc acattacttt tgaggaagta
    24421 gggccagagc tcagtgtgga acagattgta gagcttccag tcgtagcgac catcatagaa
    24481 gatcatctgg tgaagggagc cattgatatt ctggatgtgc gtttcggttc gctttggacc
    24541 tctatcacac gggaagaatt ttacaagctg gaaccagaat ttggtgatcg ttttgaagtg
    24601 accatctatc atgctgatat gctggtttat caaaatcagg ttgtctatgg caaatcattt
    24661 gcagatgtga gaattgggca acccatcctt tacatcaact ctctctatcg tttaggtttg
    24721 gctatcaacc aaggttcctt tgccaaggcc tataatgtag gtgtcggttc atcttggacc
    24781 attgaaataa agaaaataga aggataaaat aggagaatag tatggaaatt aaatttacaa
    24841 ttaaacaagt tgttgctgtc ggaattggcg ctgccctctt tgtcgtcatc gggatgatca
    24901 acattccaac ccctgttcca aatacaagca tccagcttca gtatgcggta caagcgctac
    24961 tttctattat ttttggaccg attatcggtt tgcttgtcgg gttgattggt catgcaatca
    25021 aggactctct tgctggttat ggtctatggt ggacttggat tatcgctagc ggactctttg
    25081 gtttagttgt gggacttttt agaaagtacg ttcgcgtgat caatggtgtt tttgactgga
    25141 aagatattct tatttttaac ctcattcaac tacttgcaaa tgcccttgtt tggggtgtct
    25201 tggcaccact tggagatgtt gtgatttatc aagaagcggc agaaaaagta tttgcacaag
    25261 ggattgttgc gggaattgcc aatggtgtat ctgtagctat tgcaggaact cttctcttac
    25321 ttgcctatgc aggaacccaa actcgtgcag gaagtttgaa aaaggactaa tactcaatga
    25381 aaatcaaaga gcaaactagg aagttagccg caggttgctc aaaacagtgt tttgaaattg
    25441 tggatagaac tgacgaagtc agctcaaaac atggttttga ggttgtagat gaaactgacg
    25501 aagtcagtaa ccatacctac ggcaaggcga agctgacgtg gtttgaagag attttcgaag
    25561 agtataaaat gatggggaag gctgggcaac tagtcttttt cgatgtttat agattagtta
    25621 ggtaagtaag ctaggatagg aatctttttg gcgctaagat tttaagagga gagactgcaa
    25681 gaagggcttg atttatgata aaatagaagt ctaagaagcg aatgaagaga gtaagatgaa
    25741 agaagctata attgagtgga aggatttctc tttccggtat gaaacacaac aagaaccgac
    25801 cttgcaaggg atagacttga ccatttacaa gggagagaaa gtcttaattg ttggaccatc
    25861 tggatcaggt aaatctacct tgggtcagtg tttgaatggg attattccca atatttacaa
    25921 gggtcagaca tatggagaat ttttgataaa gggtcaaaca gcctttgata tgagcatcta
    25981 tgataagtct catctggtta gcacagtttt gcaggataca gatgggcagt ttattggctt
    26041 gtctgtggca gaagatttgg cgtttgctct ggaaaatgat gtgacagccc tagatgagat
    26101 gaaaggtcgt gtttataaat gggctgaaaa gctggacctt cttcctttac tggatcagcg
    26161 ccctcaggat ttgtcaggtg gacaaaagca gcgagtcagt ctggctggtg tcttgattga
    26221 tgaaagtccg attctcttgt ttgatgagcc actcgccaat ctagatccca agtcaggtca
    26281 ggatattatc gaattgattg accagattca taaggaagag gggacgacga ctcttattat
    26341 cgagcaccgt ttggaggatg ttctgcatcg ccctgtggat cggattgtct tgataaacga
    26401 tggtcgtatc ctttttaatg ggagccctga ccagttgctt gcaactgatt tattgactca
    26461 aaatggaatt cgagaacccc tttatctaac gactctccgt caattaggtg tggacttagt
    26521 caagaaagaa cagttagcga atctggataa catgtctatc tcaaaaggtc aggttcagct
    26581 gcagaatgaa ctggcaaaag aaactccaga attgcagtca ctctttaaat tagaggacgt
    26641 gtctttctct tatgatgata gaccgatttt aaaatcccta catttagata ttaaaaaggg
    26701 tgaaaagatt gctattgtcg gaaaaaatgg agcagggaaa tcaactctag ccaaggctat
    26761 aagtagcttt attcagacgg aaggacgcta tctttgggaa aaacaggata taaaaggcga
    26821 ttctgttgca gagcgggcgg aacgagtagg ctatgtgcta caaaatccta atcaaatgat
    26881 ttcaaccaat atgatttttg atgaggtggc tctagggctc cgtttgcgag gtgtggatga
    26941 gaaggaaatt gaaacgagag tctatgaaac cttgaaaatc tgtggacttt atgaattccg
    27001 taattggcct atttctgccc tgtcatttgg tcagaaaaaa cgtgtcacca ttgcttcaat
    27061 tttggtctta ggagctgaaa ttattctcct agatgaaccg actgcaggtc aagatcagaa
    27121 gaactatact gagattatgg aatttctcga agagttacat caaaaagggc ataccattgt
    27181 catgattacc catgatatgc aattgatgct ggattattca gaccgggtcc ttgtcatggt
    27241 ggatggagaa ttgattgccg atactgttcc agccagtctg ttgagagatc ctgagctgtt
    27301 agtaaaagcc aatctaaaag aaacctccat ctttaacttg gctaagaaac tagatgtgga
    27361 tccactggat ttaacggcat tttacaaaga aaggagagag ggatgcaagc taaattaatc
    27421 ggttaccagc atagagatac tgtgattcat cgcttgtcgg gagctgggaa acttctcttt
    27481 ttcattctgg tatcattggc ggccatgatt agctatgata ccagaatgct cttgctgatt
    27541 gccatctttt cagtctttct cctctattta tcagaaattc gctttaaaga tgtttccttt
    27601 gtagccgttt ttgcgacggt atttgccgtt ttaaacgttt tgatggtcta tctcttttct
    27661 cccgagtatg gggttggact ttacggagag agaagtgtga tttggcaggg aatcggtgcc
    27721 tacactctga ccagtcaaga gctcttttat ctgctaaatt tggctattaa gtacctttgc
    27781 actattcctc tggctattat ctttttgatg acaacccacc ctagtcagtt tgcttccagt
    27841 ttaaatcaaa ttggtgtgcc ttacaagatt gcctattctg tcagtctaac cttgcgctat
    27901 attccagatt tgcaggaaga attctttacc atcaagatgt ctcaggaagc gcgtgggatg
    27961 gaattatcca agaaagcttc tcttatgcaa cgaatcaaag gcaatctgct cattattact
    28021 cccttgattt ttagctcgct agaacgcatt gataccattg cgactgccat ggagcttcgc
    28081 cgctttggga aagagaaaaa acgcacatgg tatagttatc aggccttgaa aaaaggagac
    28141 tatattacct tgctcttggc aaccttgttt ttagtagtta gtttactact tatcttgcag
    28201 aatcagggac gattttacaa cccttggaaa tagcttgaaa aaattgaaaa aatcaagtca
    28261 tttctattga caatgattct gaaagtgtta tactaagaaa gtagtttcgc tgatttactt
    28321 caaacctgtt gtgaggtaag ttaacgatgc cttaaccacg ctgtttgctg agcttgactc
    28381 cgggcagtgt ggctattttt ttgcaatggt gaaaggaagc aagtcatgac aaatcacatt
    28441 gtattatttg aacctcaaat tccacaaaat acaggcaata tcgcgcgtac ttgcgctgcg
    28501 accaattctc ccctccacat catcaagcct atgggctttc ctattgatga ccgcaagatg
    28561 aagcgggctg gattggatta ctgggataag ctagagattt atttttacga gagcttagaa
    28621 gatttcatgt ctcagatgaa gggaaaactc tatctgattt cgaaattcgc ggaaaaaatc
    28681 tattctgagg tggatttatc gactgacgag gaccattatt ttctctttgg acgtgaagac
    28741 aagggcttac ctgaagattt tatgcgagaa catcctgaga aggctcttcg tattcccatg
    28801 aatgatgaac atgtccgcag tctcaatgtg tctaataccg tctgcatgat tgtctatgag
    28861 gctcttcgcc agcagaactt tgcaggtctt gaactcgtcc atacctatga agtggataaa
    28921 ttgaaataaa aaatgaaaat gaacaaaatg cttgcgcttg caagcgtttt ttgttatgat
    28981 aaaagagtct tcagggcagg gtgtgattcc cgaccggcgg tgactttaac taggaaatga
    29041 tcttttcctt ttatactttg ttgacaagct ttgcctaacc agaagttatg cctacagctt
    29101 gtcgcctagt ctaaaagaaa aatctctatt tccttctctt taaagaagtc cgcgagcgca
    29161 agctgatgtg gtgagattcc acaaccgaca gtatagtctg gatgggagaa gacgaaagaa
    29221 tagctttgtc tgttttgata gatttatagc cggattgtaa ccacttgctt tgtttttctt
    29281 taatagagta agagggaact tttgggatat aaaaagtgag aatagataga ggaatccttt
    29341 ccaacttctt ctgattttat agaaaattgg aggaacctgt tatgacaaac acacgtcgac
    29401 tttcgaccat tgcaattcta tcagccatct catttgtgct gatgtacttt gactttccgc
    29461 ttttaccagc ggcatctttc ctcaagatcg aatttagtat cttgccagtc cttgtgggtc
    29521 tggtggtcat ggatttgcct gctgctctag gagtgctctt gcttcgctca ctattgaaat
    29581 tgcttcttaa cagccaagga gtgaatactt acattggttt gccgatgaat atcgtagctt
    29641 tgggagtttt tgtcatcgta tttgctttga tttggaaaaa ggaacggaca acccttcgtt
    29701 tcctactagg ctctctagct ggaactgttg gtttaacctt ggccatgttg gttctcaact
    29761 atgtttatgc tgttcctttg tacgctaagt ttgctaactt tgatattgga aaaattttgg
    29821 gactttccaa ctacctaatg accatggtat taccttttaa cttgattgag ggtgtaatct
    29881 tttccgtttc attctggttg ttgtacgtcc ttttgaaacc aaccttaaaa cactatgaaa
    29941 gataaacaaa catttttaat gaagggcagt tttgcccttt tacttttcgt tattcttggc
    30001 tatatggtca aattttaccc tgaaatgttg gtcaattttg accaatcgat tcagactgcc
    30061 attcgaggag acttaccaga ttatttgact attctttttc gagccctcac acgtctgatt
    30121 gatatcccag tgattatcac ttgggttgtc attacagctt ttgtctttta tcgtaagcga
    30181 tggaagatag aaagtttctt catgctggga aatctggctt tggcaggtct tttaatcgtg
    30241 acctttaaaa atatctacca gcgcccacga ccagctattt tacatctggt ggaggagaag
    30301 ggattttcct tcccaagtgg gcattctcta gctgtaacgc tgatggtagg gactttgatt
    30361 gttattctta gtcagcggat taaagatcag gtctggagaa aaatcgtaca aatcgtcctt
    30421 ggcctctacc tagtcagtgt gctggtatca agagtctatc tgggagttca ttacccatca
    30481 gacgtccttg ccagtctctg tgtgggcttg ggagtcctgt ttatcgagtt tcccttttat
    30541 gacaagctcc gcttccaatg gcgatttaaa ggcaaacaga agtgagtatc gaattccctt
    30601 gagagaaaga aatgaaagtc aatatagcag atcttcatcc gactcaacta tatttatcag
    30661 aaaagaagtt gcaagatatt cagatgcttt accagtcggc agaaacaatc caagtcgatc
    30721 caatcagtat tcttgccttt ggagattgtt tgctgattac agatgggcat cacagggctt
    30781 atcaggcttt attggcaggt cgggatacga tttctgctga gtgggataga gatggtggtg
    30841 atgaactata tcatctctat gcgcaagctt gcgaggaaag aaagatttac tctgtttttg
    30901 atttaaaaaa tcatatctta cctctttgga tcggcatggt gagctttttt ggattgaagt
    30961 caaggagaag ggagaatggt ttccaattgg ggatattaca ctatctcagg ataatctccc
    31021 cattgtgatt gggaattccg cttaccaaca tcgaggactt ggaaaaaaga ttctaagtgc
    31081 tttgattgaa ttggctcgag taaaaggatg gaaagaattg agagtcaagg aaatctacac
    31141 ctacaatcat gcttctagga ggtgtttcaa gtcgcttgga tttgtggaaa atggagcaac
    31201 agaaaaagga aggagtttta tattggaatt agtctaatcc tgccactttc tcccccttaa
    31261 cctttgacta ttccgcaaaa ttatcgtaaa ataaagagta aatgataaaa tgaggtcaga
    31321 gtctgttcgc tctggcgata gtagtataaa tgaggagaaa cgctttggaa ttagaagtat
    31381 ttgctgggca agaaaaaagt gaactatcta tgattgaggt agcgcgtgct atcttggaac
    31441 ttcgtggtcg cgatcatgag atgcatttta gcgatcttgt aaacgaaatt caaaactacc
    31501 ttggaacatc aaacagcgat atccgcgaag ctttgccttt gttctacaca gagttgaact
    31561 ttgacggtag cttcatctca cttggggaca acaaatgggg tcttcgttca tggtatggtg
    31621 tggacgaaat cgacgaagaa atcatcgctc ttgaagaaaa tgacgacgat gaagtagcac
    31681 caaaagctaa gaaaaaacgt gtcaatgcct ttatggatgg tgattcagat gccattgact
    31741 acaatgcaga tgatccagaa gacgaagatg catacgaagc agatccagct ctttcatacg
    31801 atgatgaaaa tccagatgat gaaaaaaatg aagtggaagc ttatgatgca gaaatcaacg
    31861 aaatcgctcc agatgacttg ggagaagatg tggatctcaa cgaagacgac gacgagtttt
    31921 cagatgacga tgctgaaacc agcgaggaat aagagttagc tattgacaat tatcctattt
    31981 ttaggtatca tattgtttgg gcacctcttt tagaggtcgg ggctccctag ttcttaggga
    32041 gctatttttg ttttttcaag aagttatctt cttgtatttt atactcaatg aaaatcaaag
    32101 agcaagctag gaaactagcc gtaggctgct caaaacactg ttttgaggtt gtagataaga
    32161 ctgacaaagt caggaacaca tatctacggc aaggcgacgt tgacgcggtt tgaagagatt
    32221 ttcgaagagt attagttgtg aatctggtgc agtcgtccca gattattctt attagtaggg
    32281 tcttgttttc tatatcccct cgtagttaac aagaccttga gcattttaga aagaggaatc
    32341 tatgtctacg aaatatattt ttgtaactgg tggtgtggta tcgtctattg ggaaagggat
    32401 tgtggcagcg agtctaggcc gtctcttgaa aaatcgtggt ctcaaagtaa ccattcaaaa
    32461 gtttgaccct tatatcaata ttgatccggg aaccatgagt ccttaccagc acggggaagt
    32521 ttttgtgaca gatgacggag ctgagacaga tttggacttg ggtcactatg aacgttttat
    32581 cgatatcaat ctcaacaaat attccaacgt gacaactggg aaaatttaca gtgaagttct
    32641 tcgtaaagaa cgccgtggag aataccttgg ggcaactgtt caagtcattc ctcatatcac
    32701 agatgctttg aaagaaaaaa tcaagcgtgc cgctctaacg accgactctg atgtcattat
    32761 cacagaggtt ggtggaacag taggagatat cgagtccttg ccattcctag aggctcttcg
    32821 tcagatgaag gcagatgtgg gtgcggataa tgtcatgtat atccatacaa ccttgcttcc
    32881 ttacctcaag gctgctggtg aaatgaaaac caaaccaacc caacactctg tcaaagaatt
    32941 gcgtggcttg ggaatccaac caaatatgtt ggttattcgt acagaagagc cagctggtca
    33001 aggaattaaa aataaactgg cccagttctg tgatgtggca ccagaagccg ttatcgaatc
    33061 gttggatgtt gaacaccttt accaaattcc actgaacttg caggcacaag ggatggacca
    33121 aattgtttgt gatcatttga aattagacgc accagcagcg gatatgacag aatggtcagc
    33181 catggtggac aaggtcatga acctcaagaa acaagttaag atttcccttg ttggtaagta
    33241 tgtggagttg caagatgcct atatctcagt ggtcgaagcc ttgaaacact ctggctatgt
    33301 caatgatgta gaagttaaaa tcaattgggt caatgccaat gatgtgacag cagagaatgt
    33361 agcagaactc ttgtctgatg cggacgggat catcgtacca ggtggttttg gtcaacgtgg
    33421 tacagaaggg aaaatccaag ccatccgcta tgcgcgtgaa aatgatgttc caatgttggg
    33481 agtctgcttg ggaatgcagt tgacatgtat cgagtttgct cgtcacgttt taggtcttga
    33541 aggtgccaat tctgcagagc ttgcaccaga aacaaaatac cctatcattg atatcatgcg
    33601 tgatcagatt gatattgagg atatgggtgg aacccttcgt ttgggacttt atccgtctaa
    33661 gttgaaacgt ggctctaagg ctgctgctgc ttatcacaat caagaagtgg tgcaacgccg
    33721 tcaccgtcat cgttatgagt ttaataatgc cttccgtgag cagtttgagg cagcaggttt
    33781 tgtcttttca ggagtttctc cagacaatcg tttggtagaa atcgtggaaa ttcctgaaaa
    33841 taaattcttt gtagcttgtc agtatcaccc tgaactgtca agccgtccaa accgaccaga
    33901 agaactctac actgcctttg ttactgcagc ggttgagaac agcaattagc aaaatcagaa
    33961 cctttgagaa aaatctcaga ggttttttgc atacaatgat attgcagtat atctgaggta
    34021 ggagtcctct gtatgtacct gctaccgttg aaattaatag cgactccctc ttgccctgtg
    34081 ctagtgaatg gatttatcag tatattgaaa tgaaataaaa tctgaacaaa ttaattcgga
    34141 aagccaaatc aatttctagc aaagttttag gaactggatt gtatagtgaa ttgaaataag
    34201 atatgaaca
//
LOCUS       DAVLCS010000022        33523 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLCS010000022 DAVLCS010000000
VERSION     DAVLCS010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33523
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.022"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(655..990)
                     /locus_tag="VXC78_001177"
     CDS             complement(655..990)
                     /locus_tag="VXC78_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583268.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(1081..2391)
                     /gene="der"
                     /locus_tag="VXC78_001178"
     CDS             complement(1081..2391)
                     /gene="der"
                     /locus_tag="VXC78_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV0583269.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(2405..3118)
                     /locus_tag="VXC78_001179"
     CDS             complement(2405..3118)
                     /locus_tag="VXC78_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV0583270.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(3115..4011)
                     /gene="dnaI"
                     /locus_tag="VXC78_001180"
     CDS             complement(3115..4011)
                     /gene="dnaI"
                     /locus_tag="VXC78_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV0583271.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(4012..5181)
                     /locus_tag="VXC78_001181"
     CDS             complement(4012..5181)
                     /locus_tag="VXC78_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV0583272.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEYPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(5182..5655)
                     /gene="nrdR"
                     /locus_tag="VXC78_001182"
     CDS             complement(5182..5655)
                     /gene="nrdR"
                     /locus_tag="VXC78_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV0583273.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            5795..6160
                     /locus_tag="VXC78_001183"
     CDS             5795..6160
                     /locus_tag="VXC78_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0583274.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            6165..6860
                     /locus_tag="VXC78_001184"
     CDS             6165..6860
                     /locus_tag="VXC78_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583275.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            6877..7644
                     /locus_tag="VXC78_001185"
     CDS             6877..7644
                     /locus_tag="VXC78_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583276.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(7997..9196)
                     /locus_tag="VXC78_001186"
     CDS             complement(7997..9196)
                     /locus_tag="VXC78_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0583277.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(9193..10086)
                     /locus_tag="VXC78_001187"
     CDS             complement(9193..10086)
                     /locus_tag="VXC78_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583278.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARLGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            10202..10282
                     /locus_tag="VXC78_001188"
                     /pseudo
     CDS             10202..10282
                     /locus_tag="VXC78_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            10767..10980
                     /locus_tag="VXC78_001189"
                     /pseudo
     CDS             10767..10980
                     /locus_tag="VXC78_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11395..12012
                     /locus_tag="VXC78_001190"
     CDS             11395..12012
                     /locus_tag="VXC78_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV0583279.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(12332..13219)
                     /locus_tag="VXC78_001191"
     CDS             complement(12332..13219)
                     /locus_tag="VXC78_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0583280.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(13368..15305)
                     /locus_tag="VXC78_001192"
     CDS             complement(13368..15305)
                     /locus_tag="VXC78_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEV0583281.1"
                     /translation="MDYSKVAAEVIGAVGKDNLVAAAHCATRLRLVLKDEAKVNQAAL
                     DNNADVKGTFSTNGQYQIIIGPGDVNFVYAEIIKKTGLKEVSTDDLKEIANKDKKFNP
                     LMDLIKLLSDIFVPIIPALVAGGLLMALRNFLTSPDLFGPQSIEDMYPAIKGFSAMIQ
                     LMSAAPFMFLPVLVGISAAKRFGANQFLGAAIGMIMTTPDLGGKEAFWDILGFHVTQT
                     NYAYQVIPVLVAVWLLANLEKFFHKKLPSAVDFTFTPLLSVMITGFLTFTVIGPVMLV
                     VSDAITNAIVWLYNTTGAFGMGLFGGTYSLIVMTGLHQSFPAIETQLLSAYNNNGTGF
                     GDYIFVVASMANVAQGAATLAVYFLTKNAKTKGLSSSAAVSAFLGITEPALFGVNLKY
                     KFPFFCALAGSAIGAFVAGLTHVIAVSLGAAGFIGFLSIKAGSIPMYIIAEIMSFVAA
                     FAFTYFYGKTKAASVFADEAATATAETVTEPTVEAPVVEETDTLQNETLVTPIVGDVV
                     ALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLI
                     HVGIDTVSMNGDGFEAKVAQGDKVKVGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYA
                     SVAPVATGSVAKGDAVIEVKI"
     gene            15681..17135
                     /locus_tag="VXC78_001193"
     CDS             15681..17135
                     /locus_tag="VXC78_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0583282.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            17116..18081
                     /locus_tag="VXC78_001194"
     CDS             17116..18081
                     /locus_tag="VXC78_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0583283.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(18116..19390)
                     /locus_tag="VXC78_001195"
     CDS             complement(18116..19390)
                     /locus_tag="VXC78_001195"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV0583284.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(19390..20562)
                     /locus_tag="VXC78_001196"
     CDS             complement(19390..20562)
                     /locus_tag="VXC78_001196"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV0583285.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETKSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(20693..20941)
                     /locus_tag="VXC78_001197"
     CDS             complement(20693..20941)
                     /locus_tag="VXC78_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583286.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIDELSSN"
     gene            complement(21009..21635)
                     /locus_tag="VXC78_001198"
                     /pseudo
     CDS             complement(21009..21635)
                     /locus_tag="VXC78_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(21697..22146)
                     /locus_tag="VXC78_001199"
     CDS             complement(21697..22146)
                     /locus_tag="VXC78_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0583287.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(22148..22906)
                     /locus_tag="VXC78_001200"
     CDS             complement(22148..22906)
                     /locus_tag="VXC78_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0583288.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(23021..25000)
                     /gene="pknB"
                     /locus_tag="VXC78_001201"
     CDS             complement(23021..25000)
                     /gene="pknB"
                     /locus_tag="VXC78_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV0583289.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKAQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(24997..25737)
                     /locus_tag="VXC78_001202"
     CDS             complement(24997..25737)
                     /locus_tag="VXC78_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV0583290.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIVDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(25752..27065)
                     /gene="rsmB"
                     /locus_tag="VXC78_001203"
     CDS             complement(25752..27065)
                     /gene="rsmB"
                     /locus_tag="VXC78_001203"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV0583291.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(27058..27993)
                     /locus_tag="VXC78_001204"
     CDS             complement(27058..27993)
                     /locus_tag="VXC78_001204"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV0583292.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(28006..30402)
                     /locus_tag="VXC78_001205"
     CDS             complement(28006..30402)
                     /locus_tag="VXC78_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV0583293.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(30468..30782)
                     /locus_tag="VXC78_001206"
     CDS             complement(30468..30782)
                     /locus_tag="VXC78_001206"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV0583294.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(30807..31433)
                     /gene="gmk"
                     /locus_tag="VXC78_001207"
     CDS             complement(30807..31433)
                     /gene="gmk"
                     /locus_tag="VXC78_001207"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV0583295.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(31563..33176)
                     /locus_tag="VXC78_001208"
     CDS             complement(31563..33176)
                     /locus_tag="VXC78_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV0583296.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
BASE COUNT         9479 a         7612 c         6430 g        10002 t
ORIGIN      
        1 aattagggga tctaaagcat tttataccaa tgttttataa gttgtattgt attattccat
       61 attcaatcca ctatacaaga tgaatatttc tctcaagttt cataatcaaa ataaaaatga
      121 ctgtatctat agctccataa aaaaatcata gatacagtca ttttttagtt cctacacctt
      181 cctttatgca cacctttaga cttccctagt tcccgtctca agtcaagcat ttttttgaaa
      241 cagatatagt ctaaccagtc actagcaaaa gcgataagta gtaataatag ccaaacaccc
      301 caagacttga tgtctgccac atttctcaag acgatattga acaacaggac cgaaaaaact
      361 gtccaagcca gactaaaaag agcatagagg gtgatgtaaa tccagtaaaa atagtaaaaa
      421 attgagaaaa tcttactatc tctgtttgcc ctttcaatcc agctgaaaaa gtaaaaacag
      481 ggtaataaga ttaccatttt aaacaagtgt tccatcacaa acctcctctt ttaaattgtt
      541 ttctttagtt tcgttctatt aaatgttatt accaatataa accttggaat agcgtgtaat
      601 aaatgatttt agaggtacca taagccacct cctacaaata gaaaccgata taaatcaatg
      661 ccttccaccc ttagacttcc ctagttcctg tctcaagcga aacatttctt tgaaacagga
      721 ataagttaac caattcatac caatagctag cagaataaaa agaaaccaaa tgccccataa
      781 cttgatatct gtcacatttc tcaagacggt attgaaaaac agaactgaaa caactgtcca
      841 agcaaggcta aaaagagaat agaaggggat gtaaaaccag taaaaataat aaaaaattgg
      901 aaaaaactta ctatttctgt tggccttctc aatccagtta tcaaaataaa agtacggtgc
      961 taaaagtaag aatttaaaca aatgttccat caccgacatc accctccttc ttttgatagc
     1021 gttttctatt attttattat atcaaaaaaa tccggaactg tcattccaga ttctactttt
     1081 ttatttgcgt tttcttgcga tgagatgaat cggtgttcct tcaaaaacaa aggccttgcg
     1141 gatttgattt tccaagaaac gcaggtaaga aaagtgcatg agttcttctt cattgacaaa
     1201 gatgacaaag gttggtggtt tggttgccac ttgggtcgca tagaaaatct tgagacgttt
     1261 tcctttgtct gtcggtgttg ggttgatggc aatggcatcc atgatgacat cgttcaagac
     1321 agctgatgga atacgtgtat tttgactttc gctgatttgc ttaatcatct caggaagttt
     1381 gtggagacgt tgcttggtta aagctgatac aaagataatc ggtgcgtaag gcaggtattg
     1441 gaactgctca cggatatctt cttcccagtt tttcatagtg tggttatctt tttcaagcgt
     1501 atcccacttg ttgaccacga taatcatccc tttaccagct tcatgggcaa atcctgcgat
     1561 acgcttgtcg tactcacgaa tgccttcttc cgcattgatg accatcaaga ccacatctga
     1621 acggtcaata gcacgcatgg cacgcataac agagtatttc tcagtatttt cataaacctt
     1681 accagactta cgcataccag ccgtatcaat catggtaaac tcttgaccat ctgtatctgt
     1741 aaagtgggta tcaatggcat cacgagttgt tccagcaaca ggactagcaa taacacggtc
     1801 ttcgcccaag atagcattga tcaagcttga ttttccaacg tttggacgac caatcaggct
     1861 aaacttaatg acatctggat tttcttcttc atattcattt ggaaggtttt ccacaatcgc
     1921 atctagtaca tcccctgtac cgataccatg gacagatgag ataggcagtg gttcacccaa
     1981 accgagggca tagaaatcat agatatcatt tcgcatctca gggttgtcta ccttgttaac
     2041 tgcgaggata actggtttgt gggtcttata aagcttacgg gctacgtatt cgtctgcatc
     2101 ggtaattcct tccttaccgg acacgacaaa gacgataaca tctgcttctt ccatggcaat
     2161 ttctgcctgg tgcttgattt gttccatgaa aggagcatca acatcatcaa ttcctcctgt
     2221 atcaatcatg ctaaaagaac gattgagcca ctcacccgtt gcataaatac ggtcacgtgt
     2281 cactccttcg acatcttcta caatggagat tcgctcacca gcgatccgat taaatagggt
     2341 tgatttccca acattgggac gtcctacaat ggcaatagtt ggtagggcca taatttctca
     2401 ctttctacaa taatttcttc tgttcaagat tttttctagt tgagcttggt tcagcttgac
     2461 caaactgttc tgctagacgc tgactccagc ttgtggtcgc acgcgcccca gcatagtcag
     2521 cctgaacacg gtcataagct tggattgcct cagttgactg ttcttggtat tcttcctcaa
     2581 agacaacatt ctctagtggc agtctcggtt tcatatcatg atgttgattt ggcacaccca
     2641 gtgccatccc aaagacagaa taggtgtagt caggtaggtt aaagagctct gccacttctt
     2701 cagacttgta tcgaaccaaa ccgataatca caccaccata gcccaagctt tcagctgcca
     2761 acaaggcatt ttgtccagca agagctgcat cgaccgaact aatcaagaga ccttccacac
     2821 cttggggttg gaaggtgtcg gtatgaagtc gggctccctt ttctgctcgg ttcaaatctc
     2881 cgacaaagag aaggaaaaca gcagactggc gaatggcttc ttgaggtacc aattcataca
     2941 aggcatcttt cttctcttga cttcgtacca caatcacaga gtaggattgg aaattcttcc
     3001 aagatgatgc catctgggct gctgtcaaaa tctcatttaa gtctacttgg ggaatttctt
     3061 gctctttaaa cctgcgcact gaagtatgag ccttcatcaa tttaatggtt tctgtcatcg
     3121 acggtttact ccttctaaac gagtctcctc agccaaataa cggatgcgtt ccatgacccg
     3181 tctggcttcc caggtttcgt catttccatg tttcactttc gcaaaatgct tctccaaatc
     3241 ttcaaagttg aagttggatg tgaaaaaggt cggtaaattt tcctgcatcc gatattggag
     3301 aatgacctgc aggatttcgt cacgcaccca aacggttgat tgctcggcgc caatatcatc
     3361 taaaatcagg acctcagaca gcttaatctc atccaccaag gtcttaacat tgccatcact
     3421 gatagcattt ttgacatcaa tgacaaagct aggatagtgg aggagagttg atgaaacacc
     3481 acgtttttct gataaatcat gagctaaggc cgccaccatg aaacttttac ccacaccaaa
     3541 gtctccatat aagtaaagac cttttcgaat agctggatat tgctccacga aggctagtag
     3601 cttttcaaaa actggtaagc gccccaaatc atccaagtca acttgagcca aactagcttt
     3661 cttgagactg gctggtagat tgattaactt gagacggttc ttaatagccg cttctttttc
     3721 agccgcgatt agctcaggag tttcttcata tgaaacatct gcatagccat gattcttaac
     3781 caaaatcggc ttgtagcctt tggcaatata atccgtatcc ccacggagaa acttgtcacg
     3841 ctcggtgatg tactgattaa acttggagat actgcgattt aattcctctg gagtcaagga
     3901 ttcttgctgg ataaaagccg caacatcagg gtccttcatg attttctgga ccaaatcttg
     3961 ataataaaaa cggctgggtt gacgtttgag tacgtctccg acactttcca tctaatctcc
     4021 tcctttttct aatcgagcta atagttcttg cttcttacgt tctagttcca gacgagtttc
     4081 ctcgctggtt tcattcttat attcaggatt actccattta ggaacattgg tttttactgg
     4141 ggcagtctga ttctgttttt gtgtttttgc tttctgtcct cgctcacgga tgcgcaagac
     4201 tgccttttct gccgaatgaa tcttttgata ggcatagtca ttggctacct tcatggcata
     4261 tttctcattg atatttgccg aatcgacctt attaaaggtc aataaaagaa tgatattgat
     4321 gacttcgtcc agcaagccca agccagccat ctgttgcaag agttctcttt ctgtttgggt
     4381 aatggttccc ttgcgtgttt gcttgatttc tgccaagaac tgcagggcag ttttactttt
     4441 ggcttctttg ataatggttg tttccttaag actaaagtca gaggaaactg gtttttgagc
     4501 aattttttca cgcatgcgtt tggttgaaat aacctgagaa acagctgttg acttggccaa
     4561 ttgataggtt tcaaaccaag tccatttctt ctcctcggca atagcaaaga ggtttaagac
     4621 atcggactgc tcatccgcaa aacgaagtcc atctcgagcc atcagctggc gaaaatgttc
     4681 caagtcaaaa tcattggcca ctttcttctt gagaccaagg tcttcttgac tgcctagttc
     4741 tgccaattct ggaaagactt gattgagtga gacaggtatt tcttcaccat cagcactttc
     4801 aactttcaaa tcctccacag cagagtcgcc aatctttttc tctaagagtc tgcgataaac
     4861 aggatactcc aagaagtctt gactagatag aggagcatgg agggctagct gataaacatc
     4921 ccccttttga tagagggtca agagattaaa agcagataag attttcaatg attttatcag
     4981 tctatccatc ccaaagttga gatgattgag gatacttgaa aaaagatatt cctttctacc
     5041 attatcccaa aaactgattg tataaagata aaggctcagt gcctcctgac cgataatcgg
     5101 gaggtagcac tgtaccagag atgaggtatc ttgcgacacc cgattattct ttagataaga
     5161 aaaacggtca attggcttca tttatctttc ctttttcttt ttagaggact gggtgatttg
     5221 ttggagcaag ctctctaact cactgacatc cttaaaacta cgatagacac tagcaaaacg
     5281 tacataggta atctcgtcca attcagccaa ctcctccatg acgagtgaac caatgtcctc
     5341 actttgaatt tcattttcat ttcgaccacg gagtttctgt tcgatacgat tgactaccat
     5401 gttgatttca tcacttgaca caggacgttt ctgggctgag cggataatcc cattaaagat
     5461 tttatctctg gagaattgtt cccgtgtgcc atctttttta acaaccacta aggttctttc
     5521 ttctactcgt tcgtaggttg taaaacggtg ttggcactcg tcgcactctc gtcttctacg
     5581 aatggtgttc ccttcttctg cttggcgact atcgataaca cttgacttgg tagccccaca
     5641 ttttggacaa cgcatccttt ccctccttat cgttttcttt tcattatacc attttttaag
     5701 cgattcccaa aacaattctt ctttttgctt gacaagtttt ttgttttgtt gtattattta
     5761 attaagacaa aagggtaaga gaaaggagac taagatgtcc tggacatttg acaacaaaaa
     5821 acccatctat ttacagatta tggagaaaat caagcttcag attgtttccc atacactgga
     5881 acccaatcaa caacttccaa ccgtgaggga gctagctagt gaggctggtg tcaatcccaa
     5941 taccatccaa agagccttat cagaccttga acgagaagga tttgtctaca gcaagcgaac
     6001 aactggacga tttgtgacta aggataagga gctaatcgct cagtcacgca aacaattatc
     6061 agaagaagaa ttggaacact tcgtttcctc catgacccat tttggctatg aaaaagaaga
     6121 actaccaggc gtagtcagtg attatattaa aggagtttaa gcctatgtca ttactagcat
     6181 ttgaaaatgt atccaaatca tatggagcaa caccagccct tgaaaatgtt tctcttgaca
     6241 ttccagctgg aaaaattgtc ggccttcttg ggccaaacgg ctcaggaaaa acaaccctga
     6301 ttaaactaat taatggcctc ttacaaccag atcaaggacg tgtcctcatc aacgacatgg
     6361 acccaagccc agcaaccaag gccgttgtag cttatttgcc tgatacgacc tatctcaatg
     6421 agcaaatgaa ggtcaaagaa gccctaacct acttcaagac cttctataaa gatttcaatc
     6481 ttgaacgcgc ccatcatcta cttgcagacc tgggcattga tgaaaatagt cgtctcaaga
     6541 aactatcaaa aggaaacaaa gaaaaggttc aactgatttt ggttatgagc cgtgatgctc
     6601 gtctctatgt tttggatgaa cccattggtg gggtggatcc agcagcccgt gcttatatcc
     6661 tcaataccat tatcaacaac tactcaccaa cttctaccgt tttgatttct acccacttga
     6721 tttctgatat cgagccaatc ttggatgaaa ttgtcttcct aaaagacgga aaagtcgtcc
     6781 gtcaaggaaa tgtagatgat attcgctacg agtcaggtga atccattgac caactcttcc
     6841 gtcaggaatt taaggcctaa gcaaaggaga ttatttatgt tttggaattt agttcactac
     6901 gaatttaaaa atgttaacaa gtggtattta gccctctacg cagccgtgct agtcctttct
     6961 gccctcatcg gaatacagac acaaggcttt aaaaatctac cttaccaaga aagtcaggct
     7021 actatgctac tttttctagc tacagtcttt ggtggcttga tgcttacact tgcgatttca
     7081 accattttct tgattattaa acgcttcaaa ggtagtgtct acgaccgaca aggctatctg
     7141 actttgacct tgccagtttc tgaacaccat atcatcacag ccaaactaat cggtgccttt
     7201 atctggtcat tgattagcac cgctgtattg gctctaagtg ctgttattat tctggcttta
     7261 acagctccag aatggattcc tctttcttat gtgattacat ttgtagaaac acatctccct
     7321 cagatctttc ttacaggtat atccttccta ctaaatacca tttcaggaat cctctgcatc
     7381 tacctggcta tttccattgg acagcttttc aatgaatacc gtacagcact cgctgttgca
     7441 gcctacattg gtatccaaat cgtcattgga tttattgaac ttttcttcaa tcttagttcc
     7501 aatttctatg tcaattcact ggtaggactc aatgaccatt tctatatggg agcaggtata
     7561 gccattgtta aagaactcat attcatagct atcttttatc tcggaaccta ctacatcttg
     7621 agaaataagg ttaatttgct ttaaataatt tttacctaga tatgtaacat actcatagaa
     7681 caaaagagac caggcaaaaa gtctttaaaa ttagaaaacg catagtatca agtgttaaaa
     7741 atccttgata ttatgcgttt tttgtgagct gacttatttc ctttcgctat atcgcaaaat
     7801 gaaataagaa cggaacgatg ggattttgga attcaaatca atttataaga atgttttaga
     7861 agtaatatta tcctattcca gattcagttc actatacaat tgagttttca agcaacctgt
     7921 ttacataatg tgtacataat taggttcgtg attccaccct tttcaccttt aaaaacctcg
     7981 ctttcgcaag gctcttctat ttataagata aggcacgttt aaaggttttc caaatcccta
     8041 aatcatccgt ttgaagaacg agactagcat acatgcgtcc gataaatcct gttgctacca
     8101 ccgcaaaaat cactgtaata gcaagtgaaa tccatgcttc tgctcccccc gcatagccat
     8161 taatcgttcg aaacggcata aagaaggtcg aaataaaggg aatataagaa ccaatcttca
     8221 agaggagatt gtcaccagct gcacctagag ctgtcactcc aaaaaaacca cccataatca
     8281 aaatcatcaa aggcgacaag gctttccctg agtcctcagg acgagaaacc atagatccta
     8341 ggaaggctgc caagactacg tacatgaaaa gactgatcaa aataaagagc aaggtattca
     8401 gtgagatagc atctcccaag tgatccaaaa taccagactg agccaagaat ggcaaatctt
     8461 taaagagcaa aacggcagcc agaccaccta caacatagat cccaatatgc gttaaaatca
     8521 ctagaaacag agccatcatc cgcgcataga aatagtgact tgcccttatg ctagaaaaaa
     8581 cgacttccat aattttggtg cctttttcac tggcaacttc ctgagctgtt acacccgcat
     8641 aggtaatcag aatcatataa agaaagaatc ctaaggcacc tgctgcaatt gtttgaataa
     8701 actttttatt ttccttggct tcatcaatct tttctgtgaa ttgaattgtc tgcgctaagc
     8761 gtttttcctg ctcttgagac aaggaagcag ttgaacgatt aagctgattt tgcagttcat
     8821 tgagtgtacc tgtaacctca aatttaattc cattttcaag cgatgtttcg ccatgataaa
     8881 ctgcctttag aacactatct tcttgatcaa tggtcaaata accttttaat ttttcttctt
     8941 taattgcttc tttggcactt gcttcgtctt tatagtcgaa gttaacacca tttacattct
     9001 tcagtccttc tgctacagat ggcactgttg tcactactgc cactttatta tttttagcca
     9061 tagaagaacc ttggatatgc ccaattccta cagagattcc taaaaagagg aacggcgaaa
     9121 tcaccataaa gaagaaactc catgactcga catgtcgaag ataggtttcc ttgattacaa
     9181 cccacatatt tctcatactt ccactcctga ttctagttta aagatttcat cgatagttgg
     9241 cgcttgttgg tcaaatgttg cgatatattg accttgagtc aagattggga agagttccct
     9301 tccagcgctc tcatcctcca aaatcaattt ccaactgcct tgtttggtca agctcacctg
     9361 tttgacatga ggaagatttt ccaattcttc cttgcttcgt tcacttgaaa caaagagacg
     9421 cgttttcccg tattgattgc ggacatcctg aactggtccg tgcaagacca cacggccatc
     9481 tcggatcatc agaatatcgt cacaaagttc ctcaacattg gtcatgacat ggtcagaaaa
     9541 gataatggtt gctccgcgct ctttttcctg aaaaatgact tgtttgagca attctgtatt
     9601 aactgggtcc aatccactaa aaggctcatc caagataatc aggtctggtt catgaatcag
     9661 agtaataatg agctgaatct tctgctgatt tccttttgac agactcttga ttttatctgt
     9721 cagctttcct ttcacttcca acctcttcat ccattgaggg agtttttctt tgacttcttt
     9781 ggcatccatg ccttttagag tcgccaagta gcgaacttgt tcaagaactg tcaatttagg
     9841 catgagactg cgttcttcag gcagataacc aatccgagca taggtctcct gacgaatatc
     9901 ctgaccatcc agaccgattt ctccctgata ttctaggaat ttcaaaatac tatggaaaat
     9961 cgttgttttt ccagcaccat tttttccgac tagtcccaaa atacgaccta gtcgcgcttg
    10021 aaagtcaata ccaaacaaaa cttgcttgga gccaaaactt ttctctagac ttcttacttc
    10081 tagcatcttt cacctccgaa atttcttgca ctcattatac tcctttttga tagcctttac
    10141 aatgtttttg tccattttta gaagactatt gctgtgtaaa atatggcctg gagcactttt
    10201 atactcaatg aaaagcaaag agcgaactag gaagctagcc gtaggctgct caaagtacag
    10261 ctttgaggtt gcagataaaa ctgacgaagt cagctcaaaa cactgttttg aggttgtgga
    10321 tagaactgac gaagtcagta actatatcta cggcaaggcg aagctaacgt ggtttgaaga
    10381 gattttcgaa gagtattagt gataaatcca ttatacagta gcaaactcaa tttatacctt
    10441 ccgctcctca actgtctatt tttaatcctg aattgttatt tgagtaactc ctttttcctc
    10501 ataaagtttt cttcctctaa aacttctgga aaaaagcgaa tagtttcaga caacattttt
    10561 ataagaaaca agttcatctg tcatttcaag aaggagtaat cctttatcta ctaatggacg
    10621 gaacggaatt caaccgcttg tccgatatat tttctaagga ttatatagta aaatgaaata
    10681 aaaacaggac aaatagatcg ggacagtcaa atcgatttct aacaatgttt tagaagtaga
    10741 tgtatactat tctagtttca atctgctata tctattatgc acacccctat aggatctaat
    10801 gaaaatcaca acaggctcat tcatagatgg ttacctcagg aaactaagaa aacgactaca
    10861 aaggaagtcg cattcatcga aaagtggatt aacaactatc ctaaaaaatg cttgaactac
    10921 aagtccccca gagaagactt ctggatgact aacttgaact tgaaatttag caataattaa
    10981 ttcaccatct aactatattt agtaattatt tcagaactga ttaatattaa aattaactaa
    11041 caattcaaag gattcatact agccataaat tacgtccatc agagagagac tcttactact
    11101 tttatatttt agtctttctg gcttcaggat acatataaac tttagggaaa atgactattc
    11161 gaaagcgcga atgcctcaaa attatctcag ataagctatt cgaaacttag aatgctttta
    11221 aatttatgga attgcgatta ttcgaaacct agaatgcata taacctttag ttgacagacc
    11281 tattctaagt ctcgaagggc tatttacttt ctattcctta tcaaaaaaga ctcattcccc
    11341 ctttctcctc caaaatatgg tatagtagaa atatactatc tatgaggagt ttacatgtca
    11401 caggataaac aaatgaaagc tgtttctccc cttctgcagc gagttatcaa tatctcatcg
    11461 attgtcggtg gggttgggag tttgattttc tgtatttggg cttatcaggc tgggatttta
    11521 caatccaagg aaaccctctc tgcctttatc cagcaggcag gcatctgggg tccacctctc
    11581 tttatctttt tacagatttt acagactgtc gtccctatca ttccaggggc cttgacctcg
    11641 gtggctgggg tctttatcta cgggcacatc atcgggacta tctacaacta tatcggcatc
    11701 gtgattggct gtgccattat cttttatctg gtgcgcctat acggagctgc ctttgtccag
    11761 tctgtcgtca gcaagcgcac ctacgacaag tacatcggct ggctagataa gggcaatcgt
    11821 tttgaccgct tctttatttt tatgatgatt tggcccatta gcccagctga ctttctctgt
    11881 atgctggctg ccctgaccaa gatgagtttc aagcgctaca tgactatcat cattctgacc
    11941 aaacccttta ccctcgtggt ttatacctac ggtctgacct atattattga ctttttctgg
    12001 caaatgcttt gacacgtaaa aaatccgttt ggtttcccaa gtggattttt aaagcgtaga
    12061 ttaactatag cttgatacta aatatacttt ggtatggaaa tcatgcatat ttttcgatag
    12121 tgaggcgagg acttacctag ccttcccgcc gtgatagaaa cacctgaaat ctaatggttt
    12181 caggtattcg gaaactttga gcctagtgtc tcaaagttta ggtatggaat ttcgaagaaa
    12241 gtcgctaccg tccgtaatca cttaaggaaa ggctcaaaaa tattgttttc aaccacaaaa
    12301 tccgtttggt ttcccaagcg gattttgtgc tttattttga aacttctttt gcaagaacaa
    12361 agttcccaag tgtggcagaa ccatttcctg cgactgctgg cgtcacgata tagtcacgca
    12421 catctggtac tggtaggtaa ccattaagaa gagatgtaaa tttctcacgg acacggtcca
    12481 gcatatgttg ttgagccatg acccctccac caaagacaat cacgtctggg cggaaagtca
    12541 ctgtcgcatt aaccgcagct tgagcgatat agtaggcttg aacatcccaa acagggttgt
    12601 tgagttcaat agtttcccca cgtacacctg tacgagcttc caaacttgga ccagctgcat
    12661 aaccttctag acatccctta tggaaaggac aaacaccctt aaactctttt tcaatatcca
    12721 ttgggtgtct agcaacataa taatgaccca tttcagggtg acccacacca ccgataaact
    12781 caccacgttg gatgacgcct gcaccgatac ctgtaccgat tgtgtagtaa accaagtttt
    12841 cgatacgacc accagcattg ttacgggcaa ccatttcacc gtaagcagag ctgtttacgt
    12901 ctgttgtgaa gtacattggc acgtttaggg cgcgacgaag ggcaccaagc aagtccacat
    12961 ttgcccagtt tggttttgga gtcgtcgtga taaagccata agtttttgag tttttgtcaa
    13021 tatcaatcgg cccaaatgaa ccaactgcaa gaccagcaag gttatcgaat tttgagaaga
    13081 actcaatggt tttatcgatt gtttcgattg gagttgttgt tggaaattgt gttttttcta
    13141 caacgttaaa gttttcatca ccgacagcac agacaaactt tgtaccgccc gcttccaagc
    13201 ttccatataa ttttgtcatg ataaacctct tgtttttatt ttctttatta tagcatactt
    13261 cgaaagtcta aatgtctcta ttttttagat tttcctctgt aaatcttact atctaataaa
    13321 aacgaacaaa catgtcattt gttcgttttc acattagaga ggattgatta gattttcact
    13381 tcgatcacag catccccctt cgcaactgaa cctgttgcga ctggagctac tgaagcgtag
    13441 tcagctgtat ttgtaacgat aaccattgtt gtatcatcaa gtccagctgc agcgattttg
    13501 tttgagtcaa atgttccaag aacatcgcca actttcacct tatcaccttg agcaactttt
    13561 gcttcaaaac cgtcaccgtt catagataca gtgtcaatac caacgtgaat caaaacttca
    13621 gcaccatttc ttgttttcaa accaaaagcg tgccctgttg gaaaggcaat tgaaacttca
    13681 gcatcagctg gtgcatagac cacgccttgg cttggtttca cagcgatacc ttgtcccata
    13741 gctccacttg agaagactgg gtcattgaca tcagcaagag cgacaacatc accaacgata
    13801 ggagttacaa gtgtttcatt ttgaagagta tcagtctctt ccactactgg tgcttctact
    13861 gtaggttctg taactgtttc tgcggttgct gtggcagctt catcagcaaa gacactagct
    13921 gcttttgttt tcccgtagaa ataagtgaaa gcaaaggcgg caacaaagga cataatttcc
    13981 gcaattatat acatagggat tgaaccagcc ttaatagaaa ggaatccaat aaatccagcc
    14041 gctcccaatg aaactgcaat aacgtgagtt aaacctgcta caaaggcacc aattgctgaa
    14101 ccagcaaggg cgcagaagaa tgggaatttg tatttcaagt ttaccccaaa gagagcaggt
    14161 tctgtaatac caaggaaggc agaaacagca gccgaactgg acaatccttt tgttttagca
    14221 ttttttgtca agaagtagac tgcaagagta gccgcacctt gtgctacgtt tgccattgaa
    14281 gcaacaacaa agatgtagtc tccaaatcca gtaccgttat tattgtatgc agacaacaat
    14341 tgtgtttcga ttgctgggaa tgattggtga agacccgtca taacgattaa tgagtaagtt
    14401 ccaccaaata gccccatacc aaaggcacct gttgtgttgt acaaccatac aatcgcattt
    14461 gtaatcgcat cagacacaac caacataaca ggaccgataa ctgtaaaggt aaggaatcct
    14521 gtaatcatca ctgataaaag cggtgtaaaa gtgaagtcaa ctgcagatgg caatttcttg
    14581 tggaagaatt tttctaaatt agctaacaac cagactgcaa caaggactgg aataacctga
    14641 taagcatagt ttgtttgtgt aacatggaaa cctaagatgt cccagaaggc ttctttacca
    14701 cccaaatctg gagtggtcat aatcataccg attgccgcac caaggaattg gtttgctcca
    14761 aagcgcttgg ctgctgaaat accaaccaaa acagggagga acataaatgg agcagcagac
    14821 atcaattgaa tcatagctga gaagcctttg atagcaggat acatatcttc aattgattga
    14881 ggtccaaaca aatctggtga tgtcaagaag ttccgtaaag ccatcaagag accacctgca
    14941 actaaggcag ggataatagg aacaaaaatg tctgacaaaa gtttaatcaa gtccatcaat
    15001 ggattgaact ttttgtcttt attagcaatc tctttcaaat catctgtcga aacttctttc
    15061 aaaccagttt tcttaataat ttccgcatat acgaagttaa catcaccagg accaatgata
    15121 atttgatatt gtccgttagt gctaaaagtc cccttgacat ccgcattatt atccagagct
    15181 gcttgattca cttttgcttc gtctttcaat accaagcgaa gacgtgtcgc acagtgagct
    15241 gcagctacaa gattatcctt accgacagcc ccaatgacct cggcagcaac tttactataa
    15301 tccatagcaa aaatctcctt atataacatt ttgttcttgt ttgaaagcga ttttattcgc
    15361 ccttacgact attattttat catgttttaa aaatatgtca agcgttttgc agaaaaaata
    15421 ttctatccac ttagtgggca agttttagat tgattgtttt tgactgtttc atcaggaatt
    15481 ccttgaaaaa taagtttgaa accttggtta aaaagtcttt tatttcatta tctttcacat
    15541 tttcgtaaaa atttgattga tttcctgtat gtattttatg ataatcgttt gacagttttt
    15601 cctctttttt aacataaaag gcttgcattt tttatcgaaa acagttacta ttaaaagtga
    15661 taagattttt ggaggaatga atggaatgga caactgagcg tcgttacaga ctttatcaag
    15721 attggacgca agaagaaatt caacatataa aggaaaatat ggcacaatct ccatggcata
    15781 ctcattacca tgttgagcca aaaacaggac ttctcaacga cccaaatggc ttttcttact
    15841 ttgatggcaa gtggatcctc ttttaccaga attttccttt tggtgcagcc cacggtttga
    15901 aatcttgggc acagctagaa agtgatgatt tggttcactt taaagaaact ggaatcaaag
    15961 ttttaccaga tactccatta gatagccacg gtgcctactc tggttctgcc atgcaatttg
    16021 gcgataactt attcctattt tatacaggaa atgttcgcga tgaaaactgg atccgtcacc
    16081 cataccagat cggtgctttg atggacaagg agggtaagat tacaaagatt gacaagatct
    16141 tgattgacca gccagcagac tctactgacc acttccgcga tccacaaatt tttaacttta
    16201 aaggtcaata ctatgctgtc gtcggtggac aggacttgga gaaaaaaggc ttcgtccgtc
    16261 tctacaaggc tgtcaataac gactacacaa actggcaagc agttggcgac cttgactttg
    16321 ctaacgaccg tactgcctac atgatggaat gtcctaatct ggtctttgta gaggaacatc
    16381 ctgtccttct ctactgtcca caaggattgg ataagaaagt tctagactac gataatatct
    16441 ttccaaatat gtataagatt ggggcttcct ttgaccctaa aaatgccaaa atggtagatg
    16501 tgtctcaact tcaaaacatg gattacggtt tcgaagccta tgcaactcaa gccttcaacg
    16561 ctcctgatgg gcgtgctcta gcagttagct ggcttggttt gccagatgtt tcttacccat
    16621 ctgaccgttt tgaccaccaa ggaaccttct ctttggtcaa ggaactcact atcaaagacg
    16681 acaagctcta ccagtatcca gtcgctgcta ttaaggacct tcgtgcttct gaagaagcct
    16741 tctcaaaccg ttcccaaacc aagaacactt acgaacttga actcaacttg gaagctaata
    16801 gccagagcga gattgtctta cttgctgata aagaaggtaa gggactttca atcaactttg
    16861 accttgtaaa cggtcaagtg acagtggatc gtagccaggc tggagaacag tatgcccaag
    16921 aatttgggac aactcgttct tgccctatcg agaatcaggc tactactgct acaatcttca
    16981 tcgataactc tgtctttgaa attttcatca ataaaggaga aaaagtattt tctggtcgtg
    17041 tcttcccaca tgcggaccaa aatggtatcc tgatcaaatc tggaaaccca actggaactt
    17101 actatgaatt agattatggt cgcaaaacta actgatgtcg ccaaacttgc aggcgtcagt
    17161 cctactaccg tttctcgggt tatcaataaa aaaggatatc tatctgagaa aaccatccaa
    17221 aaagtcaatg aagccatgag agaattaggc tataaaccca acaacctggc tcgtagtctg
    17281 caaggaaaat cagctaagtt aatcggcttg attttcccca atatttccaa tgttttctat
    17341 gcagaattga ttgataaatt ggaacaccaa ctcttcaaaa atggttacaa gaccatcatc
    17401 tgcaacagtg aacatgattc tgagaaggaa cgcgaataca tcgaaatgtt ggaagccaat
    17461 caggtagacg gcatcatttc tggtagtcac aacctaggaa tcgaagacta caatcgtgtg
    17521 acagcgccga ttatttcctt tgaccgaaac ctatcgccag acatccctgt tgtctcctct
    17581 gacaactatg ctggtggggt tcttgctgcc caaaccttgg tcaagacagg tgcccagtct
    17641 atcatcatga ttacagggaa tgacaattcc aattcgccaa ccggactgcg ccacgctggt
    17701 tttgcatccg tactcccaaa agctcctatt atcaatgttt ccagtgactt ttctcccgtc
    17761 agaaaagaaa tggaaatcaa gaatatcttg acccgggaaa aaccagatgc catttttgct
    17821 tcggatgatt tgacagctat tctggtcatt aaaatcgctc aagaattggg catttctgtc
    17881 ccaaaagagc tcaaggtcat cggctatgat gggacctact ttatcgaaaa ttactaccct
    17941 caattggcta ctatcaagca acctttggaa gagattgctt gtctcactat tgatcttctc
    18001 ttgcaaaaga ttgaaggcaa ggaagtcgcc acaactggtt acttcttacc agttacgcta
    18061 ttaccaggaa aaagtattta aacacaagaa aactcagacc gattcgtctg agtttttatg
    18121 atcttaaatt ttcgagatag cgctgggctg tctctaggtt aaaggtttta tctgagatga
    18181 ggcgctctac taggggagca acttcagatt cactagcccc agctaggaga gctagggatt
    18241 tggcctgtag tttcatgtgg ccttgctgga tgcccgtact taccaaggct ttgagggctg
    18301 caaaattttg agcaagaccg atggacacga taatctgggc taattctctg gcagaaggat
    18361 ttcctagtag atcatgactg agagctacac gtgggttgag gccgatagag ccacccttag
    18421 tcgctacagg catgggcagg gtcatctcac cgaccaattc ttctctttca aggtccagcg
    18481 tccagcagct aagaccttga tagcgtccat ctcgactggc aaaggcatgg gccccagctt
    18541 cgatggcacg ccagtcatta ccagtggcaa tcaaaatcgc atcaatacca ttaaaaattc
    18601 ctttattatg agtagcagct cggtaaggat cagcctgcgc aaactgacta gccaacgcaa
    18661 ttttctccgc aatctctcgt ccttgatcct tttggcggct caagtagcga aaggcgatgc
    18721 gacagcttgc agtcaccaga gaatcagtcg cgtagttgga caggattccc atgagactct
    18781 gtccctgact gagttcttct aagactggtt tcaaggcttc cagcatggtg ttgagcatat
    18841 tggcacccat ggcttcctgg gtatcgacat gaatataaac aacgagaaag tctggttcgc
    18901 cttttatctg ctcgacatgc agatcacgcg ccccacctcc acgtttaacg atagaaggat
    18961 aggcttgatt ggcaagctcc aagagctccg ctttcttgct ggcaatcttc tcttgcgcta
    19021 gtttaggatt agcaacttga taaagggcta cctgcccaat catctggcgc tgatggactt
    19081 gtgcagtaaa accacctgca cgcttgatga ttttgctggc atagctggcc gccgcaacca
    19141 cagagggttc ttctgtcaca tagggaacgg tgtattcctg accgttgaca agtacctccg
    19201 gaaccagcga ataaggcaga gaaaaagttc ccaccacatt ctcactcagc tggtctgcca
    19261 cagtcacact catctgttca tccttctcca gactagcttg tctctcagga ctaaggagcg
    19321 cctgagcttt tagcagctcg aggcgctctt ggtatgattt tttagaaaat ccattccaac
    19381 ttatcttcat tatttttcaa ccttgctata acggcgttgg tggtcaagaa tttcaaccaa
    19441 ggcaaaatct tgattttcat agccagcaaa ctgggcagat tttgtttcat ccaagtttac
    19501 ttcctcaaaa aagacctttt catagtctgc aacggatagg gcagttcgtt ggttgagctt
    19561 gttcaagcgg tctttatcca aataagcttc atatccttca accaattcac cactgaagaa
    19621 ctcagccaca gctccacttc cgtaactata aagggcgatt ttatccccag ctttcaagct
    19681 atctgtattt tccaagagag acaaaagtcc aaggaaaagt gaacctgtgt agatattccc
    19741 caccttttga ctgtagagaa tagactggtc aaaatgcttt tgtaagaggt cttttttctc
    19801 ttgaggcagg ctcttatcca tgattttttt caagcctttt agcgctaatt taggataagg
    19861 caagtggaaa caaacagccg caaaatcatc cagagtaagc tggtagcgtt tttgatattc
    19921 aagccaagtc gttttcaaac tatccaagta ttgttgggta gaataaacac catttacata
    19981 aggagttgtc gagtaatttg gtcgccagaa atccatgatg tcacgggtct gagctacatt
    20041 gtcattatta aaggccatca tgcgtggatt ttgtgtaatc aacatagcta cacttccagc
    20101 accttgagtt ggttctcccg gagtttcaat accatatttg gcaatatcac tggcaatgac
    20161 caataccttg gactccggag aattttccac atgcaatttg gcataatgga gggcagctgt
    20221 cgccccatag caggcttctt taatctcgaa actacgagca aagggctgga tgcccagcaa
    20281 gccatgcaca aagacggccg cagccttact ctggtcaatt cctgactcgg tagccacaat
    20341 gaccatgtca acttcttgtc tttcttgctc agttaaaata gagtcactag cactggccgc
    20401 caaggtcacg atgtcctcag ttaggggcgc aatactcaat tccttgagta agagtccttt
    20461 acttaatttt tcagggtcaa ttcccctcgc ttctgctaag tcttgtaatt tcaagacata
    20521 ttgactggtc gcaaaaccaa tcttatcaat accgattgtc atatttacct ctgttttatc
    20581 attcatgtaa aaaatcgttc tatactattt tatcacaaat ggcagtaaaa gagagaaaaa
    20641 agacttgatt caccaaatca agcctcttat tggtcatcat tttaaagaat gattagttgc
    20701 tagagagttc atcgatataa gtagctttat aagctccatt cacagttatc agctcctgga
    20761 ggatcaaatt tcctgagtaa gtccttccca tctcatctac aaatttttga taaaactgac
    20821 tggtcggaat ttctctgaca tccttatcaa atgtcttgtc aagtgtttta ctaaccttct
    20881 cagcaatcaa ttgatgctct tgccatccac tttgaaactc tgagcccgaa ctagaaacca
    20941 tgactgggat aaacaacaag gtcagtagac ttacagacaa taaggaaaat agtagacttc
    21001 ctgcaaaact agaatcctag ttcatgattg ataataccaa caatcaaatt cattcgtaat
    21061 ccgaagcgtt tacgatgatt tcgataggtt gttgaaatca ttttaaacgt ttttactttg
    21121 gcaaagatgt tctcaacctt gcttctctcc ttagatagcg catggttaca ggctttatct
    21181 tcagctgtta gcggcttgag tttgctggat ttacgtggag tttgtgcttg aggatatatc
    21241 ttcatgagcc cttgataacc actgtcaacc aagattttac cagcttgtcc gatatttctg
    21301 cgactcattt tgaacaactt catatcatga caatagttca cagcgatatc caaagaaaca
    21361 attctccctt gacttgtgac aatcgcttga ggttccatag aatgacattt ctattttacc
    21421 agaataattg gctagttgat ttttttagga cgatttattt ttacctctgt tgcatccaca
    21481 atcaccgtat tctcagcact aagatgagtt tttgaaatcg taacaccact ttgaacaaga
    21541 gttacttcaa cccattggct ccgacggatt aagttgcttt cgtggatacc aaaatcagcc
    21601 gtaatttctt cataagtgcg gtattctcgc acatatagaa agcgttgtta atttatttat
    21661 ctcatttttc agaaaattct tttatttctg taaagtctac gatactcgat gtgtttttat
    21721 ataatgatac agtctgagaa tcactgttcc gctagccatt ccaatagaga ttaccagagc
    21781 caacatgaca accaaggtcg cacttgccag tgctttatta tagtcccctg tcacaaaaaa
    21841 ggcagttgtt cggtaggaga gataacctgg aaccagcggt gccaaaatgg ccaagataaa
    21901 gaccacagca ggtgtcttat aaagaatact taaaatctgg ctgacacaag aaccaataat
    21961 ggctgcaatg aaggtagcta caatgacatt ggtcggttcc ttgagcaaga gatagattag
    22021 ccagacagtc atgcccaaaa tccctccagg taagagcata gaccgttgca cattgagtac
    22081 gattaaaaaa gtgataatgg caagaaaact tgctactgct tgtaataaaa aggttgttag
    22141 tgtcatatta gttcatcaat accaaggcga cagaagttcc tgcccctaaa gcgagggtaa
    22201 tgagcaggga ttcaaacatc ttactcatac cagagtttat gtggttggtc ataatatcac
    22261 ggaccgcatt ggtcaaggca atgcctggta caaacggcat gaccgcacca gctataatca
    22321 aatctgccgt tgaaggaaaa cctgtgtagc gagcccaaaa ctgggcaatt atcccaaaga
    22381 caaaggctcc agcaaaggct gtcacaaagg gaattcggat aaatttttcc acatagaggg
    22441 aaaaggcaaa accaaataag gtcgccactc ctgccccaag tgcgtcgtag atatttccgc
    22501 taaacataac tgaaaagaaa ggagcactaa aggtcgcagc cagagttacc tgcaacttag
    22561 tatagggaag gggttgagct tgcaaggccg tcaattgctt aaaggctgtt tctaagtcaa
    22621 tctgcccccc aactagctga cgagaaatct ggttcacatc gcagactttt tcgatgttat
    22681 aagaagagga ggtcacgcgc ttcatgcgcg aaatattggt attttcaata gagaaaaaga
    22741 tagcggcagg catggcaagg acattgcaat ccacaatccc ctgcgaatgc gcgattcgaa
    22801 tcatggtatc ttctacacga tggatttctg agccactttt aaggagaata gtccccgcta
    22861 gcataatcac atcaatgacg gcatttaatt cttttgattc ttccatgctt tcctcctttt
    22921 atcaactccc tctattctat cacaaatctg gactcaaaaa aaatctttgc catgaaatca
    22981 tgacaaagat tgattactca ttttgattat ccatctgctt ttaaggagta gctgaagttg
    23041 ttttaggttt gtagattgaa atcttgactc tagtcttatt taggtctacc ttttcacctg
    23101 ctctaggact ttgttcaaca accatgcctt ctacactacc tgcaggcgct gtcgtcactt
    23161 ctacaacttc tatattagct tccttaatcc caacaatttg aatcaaattg ttcttagtaa
    23221 actccaagct ggaaccaatg taactcggca tggcaacact tgtaactttt ttagctactg
    23281 tcaagacaat ttgagtaggt ttactcacat cataagtcgt tccggcacct ggactttgtt
    23341 tcataatcgt tcctggttcg ctttcgctgg actcttcttc ctctatctta atcaaattct
    23401 caggaacctt cttctgcttg agttctgaga ttacttctgt agagttccgt ccaatatagt
    23461 tccctaattg aatcgtcgta gcttttttag ctactgtcaa aacaatttga gttgccttgc
    23521 tcaagtcata ggtcgtacct tctggtagac tttgcttcaa gaccgttcca gcctcactct
    23581 cattcgactc ttcttcctca attttaatca aattatctgg aacttttttc tcttttaatt
    23641 ccgcgataac atcagaagat ttccggccga cataattact aatttggaag gattgtttgc
    23701 ctgatgagac aaccagattg attttcgttc cttcttttcg accagttcca gcgccaggat
    23761 ctgtacggat aatccgccct tcttccacct tttcactagc ctctgtcttc tcctcaccaa
    23821 tctcaaaatt ggcttttttg agcgttgcct tggcctctgc aactgtctga cctgccacat
    23881 ctggaatggc aatggttgca ggagttctgg atagtatcca aataagagaa gctgccacca
    23941 atacaaggct ggccaacaaa atcaggtaac gcatcttaaa tctatgtttt ttcggtgctt
    24001 gtggttggta agtttcctct gtcacagcct ggcttgggtt tttgattgat ttgtgttctg
    24061 tctgcgcttg agccttagga atagatgtca aggtactctg agaaaccttc ggcaaggtct
    24121 tggtatctgc cttgctcgtt tcatcaaaga ttaacttact ttcatttcta cgattgtagg
    24181 acaagctact agacaagtcc acatacatct ctgaaaccga gcggtagcga ttggtcaact
    24241 ttttagcagt cgccttgata ataacatttt ctaaagcctg aggtacagat ggattttctg
    24301 caataacgga cggcaggggt ttctggaaat gctggagggc aatggtcacc gcgctatccc
    24361 cgtcataagg gatatggcct gtcaacatct catagaaaat aatccccatg gcatagatat
    24421 cactctgcac agtcgccttc gaaccacgcg cctgctctgg tgacaagtaa tgaactgagc
    24481 ccaacatcga gttagtctgg gtcagacttg tctctgcaaa ggctacagca atcccaaagt
    24541 ctgtgacctt ggcagtccca tctggtgtca aaaggatatt ttgaggtttc aagtccctgt
    24601 gaacaattcc tcgagtatgg gccaagcgca tagccaagag aatttgtccc atgatacgga
    24661 ctgcttcttc attagaaaga ggataatgtt ccttgatata gcgtttgagg tctagtccag
    24721 caacatactc cattgcaaga tactgttgac cgtcttcctc accaatatct gttatccgaa
    24781 cgatatgagg atggtctaga tctgccatag ctctcgcttc acgctgaaaa cgagctacag
    24841 ctatcgggtc cgtctggtag ttggtcctca gaaccttcac tgccacttct tccccatcta
    24901 agattaagtc tttggctagg tagacatccg ccatgcctcc tcgaccaatc tgtttgacaa
    24961 tccgatagcg tccggcaaaa atcttgccga tttggatcat tctgcatcct cctcgttcat
    25021 agaaacaagg gcaaccgtaa tgttgtctaa acctcctgca ttgttagcaa aacgaacaag
    25081 tgtctccgtt ttatctgcta aaggaatatc actggttaca atatcacgaa tctcactgcc
    25141 tgaaatcatg ttggtcaagc cgtcactatt gagcaagaga tagtcacctg actcaaggat
    25201 aactgtccca aaatcaggct gaatttcatc tttttgccca atagactggg tgataatatt
    25261 tttttgcgga tgagcttctg cctcttctgg tgtcaattga ccagccttga gcaattcatt
    25321 aaccaaggaa tgatcgctcg tcaactgatg gtattcttct ccacgaatca agccgatacg
    25381 cgaatcacca atatgagcat agatagcctg attatcaaca atagcaagga cttccaaagt
    25441 agttcccatg cctctgtaag cttcatcctg accaagctgg tgaatctttt gattttcaat
    25501 ttctaggtaa tgggcgaacc attcacgcac ttcattgact gtatcgatct gggtatcaac
    25561 ccaagctaca cccaggtctg tgaccgccat ttcactagcg atattccctg cacgatgacc
    25621 tcccatccca tcagctaaaa taatcatggt acgtccagct ctattgacat agtggttgac
    25681 atagtcttgg ttatttgttc gtttctgacc aacatctgtt aataatgaaa tttccatgtg
    25741 tcagttcctt cctaatccga tatcttgcga aattgactga tgaagaatcc atcacttcca
    25801 tacaattcag gtgtaatgag gatacagccg tctttcatga tatccttaca ttcatgttct
    25861 agttttacct gctcgaactc gggatgactc tctaaaaagg ccttaacgac ttgaaaattc
    25921 tcctctgaga cgatagtgca ggtgctataa gttattatac cacctttgcc tagtatttga
    25981 caaacactac ctaatatttc taactgaatt tcctgcaagg acgcgaaatc tgccgtttct
    26041 ttattgtatt tgatatctgg ttttcggcgc aaaagaccga ttcctgaaca aggagcatcc
    26101 accaaaatct tatcaaagga atcctggtca aaaaactcat gcacctttct ggcatccaat
    26161 ttttgagttt gaacccgatc tgcaactccc agacgttggg cattttcttg aattaaatcc
    26221 aacttgtggt cgtacaagtc cagagcagta acctgacctg tcgtaagata agaggctata
    26281 tgggctgttt tcccacctgg agccgcacag gcatcaagca ctcgctcatc accttgtaaa
    26341 tcaagcgtcg gagcaaccaa ctgactggac tcgtcttgga tggtaatggc tccatccgca
    26401 aacaaattat gccctgcaaa atgcccctgc tccttaacca gaccagtggt tgctaaaagg
    26461 gaattattcg cctccaacaa ggcttggatt tcctcttttc gacttaggtc tgttacacga
    26521 atactggctt tgtttcgcac taacaggctt tcaaagatgg cttttgctct ctcctctccg
    26581 tattcttcct tgagtttggc aactagccaa actgggagag aataggcaat ggagtcacgc
    26641 ttgttttttc gcttgatgct agcaatatct ggccagcctt cacgcaagat acggcgaagg
    26701 acagcgttga ccaatttttc actgcctttt ttacggagtt tggccaattc cactgcttca
    26761 ttgaccacag catgatctgg aatcttgtcc aaatagcgga gttggtaggc actcatgaga
    26821 agaaggacat agagccagct gtctaactgg tctctgtctt cgataaagtg ggataggtac
    26881 cattccagag tcagtttacg ggctaccgtt ccatagacca gctcggtcac taagcccttg
    26941 tctgctgcca aaagttgact tccctttaga tgcttattta aggcgatatt tgagtatgct
    27001 tggttcacaa aaacatcctc tagcactgct agagctaaac ttctagccgt ttctacttta
    27061 gtcaccaaat cgttctccta cagtcaatgt acgtccaact ccgttgagga aggaagcaat
    27121 gtccatctta ggcttaccag ctggctgcac ttgtttgagg gatagagccc cttcagccgt
    27181 tgcgacaatc aattctttct tgccgataga gagaatctca cctggatttc cctgaccttc
    27241 tactggtagg gcttcataaa tcttaaagcg gtcgccctta aggaaagtat gggcaacagg
    27301 ccaggggttc attccacgaa tttggttaaa gagttgacga ttggttttgt tccagtccag
    27361 tttttcttcc tctggcttta tatttggaga gaaggtaacc tgactcgtat cctgcggttc
    27421 aggtttgata tcaccagcaa tataggcagg cagagtgtcc aaaagcaaat cacgaccaac
    27481 tagcgccaat ttttcaaaca aggtgccaac attgtcctca tctgtgatcg gaatgctgcg
    27541 acgagaaatc atatctcctg catccatttc cttaaccatt tccatgatgg tcacaccagc
    27601 ttcctcatcc ccttgaatca aggcataatg gataggcgca ccaccacggt gtctaggaag
    27661 gagggaggca tgaacgttga cagcaaagtc catgctatca aggagtttgc ttgggagaaa
    27721 ctgcccaaaa gcagcagtca caattccatc tgctcctagc ttcataagat cttccatctc
    27781 tggacttcca gataattttt caggttggta gatagatagt cctgcttcct tggcagcctg
    27841 cttgactggg gtttcttgga taactttttt acgaccaaca gcacggtctg gctgggtcac
    27901 aacggctaga atttcgtaac ggtcatctgt caaaagtcct tttaagactg ttgctgaaaa
    27961 gtcgggggtc cccataaaga ttagttttgt catatcttct ccttcttata aaaattgctg
    28021 cggctcatgg tcaatactga gacggagctc actattttcc cgttcttgag tcaaggccag
    28081 gacctggttg agggtcggcc ccagctcatc ttctaaacgg tatttaatta aaatctggta
    28141 atgatagagg ttgtgggtac gggcaatcgg ttttggcgtt ggccccagaa tgggactggt
    28201 ctctgacaag cctgaccgca aaatgttcat gacttcatag gcacgtttga aaacctcttc
    28261 ttctttcttg tgagaaaggg taataccaat cgtgaaatag taaggtggat agccgagttg
    28321 tcgtctgatt cccatttcat aggcataaaa gccttcgtaa tcttgatcct tggcaaatcg
    28381 aatagcatag tgctgcggat tgtaggactg tatcaagact tgacctgctt tttcagcccg
    28441 acctgctcga cctgccacct gagtcaagag ctggaaggtt ctctcagaag aacggaaatc
    28501 aggcagattc aaggccgtat ccgcatttag aactccgact agggtaacat tgggaaaatc
    28561 caaacccttt gcaatcatct gagtaccaag taaaatatcc gcttcccctc gcccaaactg
    28621 gtcaagcaag gcttggtgac tgcctttctt tcgagtcgta tccacatcca tcctcaaaat
    28681 gcgagcttgg ggaaagagtt ctgctagctc atcataagcc ttctgagttc ccgtcccata
    28741 gtaacgaata ctgcggctct tacagttagg acagacctga ggaatatcct tcgagaaacc
    28801 acaataatgg cagttcatag tcttggtatc catatgcaag gtcagagaaa tatcgcagtt
    28861 gggacaagta tccaccgtcc cacactcccg acacatgaca aagctagaat aaccacggcg
    28921 attgagcatg agaaccacct gctctttttt aaccagacgg tcttggatag cctctagcaa
    28981 aggaggcgta aagtttgacg tctcattttg tccgatatag tctcgaaagt caatcacttg
    29041 aacctcaggg attgtagcca aaggattggc acgttgggtt agacgtaagt gttgatagac
    29101 gcctttgcca gcacgtgccc ggctctctaa gctcggcgtt gcagatccaa gtaccagagt
    29161 tgcttgatta tactgagccc gtaaaatagc tacctctctg gcatggtaac ggggattgct
    29221 gtcctgctta taagccgctt catgctcttc atcaataatc atgacaccca gatttttcag
    29281 aggagcaaag atagcagatc tggcaccaac aacaacttgg gcatcgccac gctccacctt
    29341 gcgccattca tcatactttt cgccattgga taatcctgag tgaagaatgg ctaccttgtc
    29401 cccaaaacgt gctataaaac gctcggtcat ctgaggagtc aaggaaatct caggtaccag
    29461 caaaatagct gtcttaccct tatccagggc accttggata atctgcaagt aaacctcggt
    29521 cttcccactt cctgtaatcc cttgaagtag aaagggaggt tgagaactgc caatagaact
    29581 cacaaccgca tcacgcgcct gtctttgttc tggatttaac tccaaaggtc tacttgcttc
    29641 aattccttca aaataagcag ccgagcgttg aacttccttt tggactatgg taacagcacc
    29701 ttgatccaca aagaagttga cttgctctcg cgagtaggac tctaacaagc tagccaagga
    29761 agcgctctct ggatgagaca gcagataatc tctcagttcc aactttttct tggcacgtgt
    29821 agaaatctca acaccttcta attgggcatg gtcaacctca taccaagact gggtcttgac
    29881 cttcttttga tcgactgcct gatattccag accaagcagg ccttttctag tcaaacgcat
    29941 catttcagct tgcttggcaa ggtctagtga agaaaaggct agcgaatctt ctgaaccaaa
    30001 caggcgtact cgttcttcct gactcaagcc ttccagagga tagagaatct tgtcatagct
    30061 agaattcaga aaccctggaa gcatggcctt gaggatagag attttgtagg agaagacaga
    30121 tttgcgtaac tcctcagcca gccagagttg ttctggcgtg agaacaggag aaaaatccag
    30181 cacctctgca atatctttta aatcttgctc catctcttct ccatctgatt gggacttcaa
    30241 accaagaaca atcccttgaa tcaggcgatt acccttacca aaaggcacat gaacccgcat
    30301 cccaacttcc agcattccct caaattcctc cggaatcctg taactatagg gctggtccgt
    30361 ctgcatcaag ggcacatcta cgataatctt agctagggcc atcttctcac ctcctccttg
    30421 tcagtacatt cttgcaatag aaaaaataag attgagtccc cccaacctta aattttttca
    30481 ccatcttctt tttctttagc aatttgctct ttgattttct tttcttcttc ttctttgcgg
    30541 cgtttttctt cttcgatacg gcgacgcact gcttcacgtt ttccttctgg atctgggtga
    30601 attgtaacgt ttcctgattc gatttcttct aaagcgcgaa gagttgattt ttcagacttg
    30661 aaaccttgag ttgctggggc acctgcttcc aattcgtggg cacgttttgc ttccaagatt
    30721 acgagtgaat attttgaagg aaccttgtcg agcaaggtat caatagaggg ttttaacatc
    30781 atttgcttgt acctattttc taaattttat cgggtagttg gagattttgg taacatctcc
    30841 tgatagtgac caatgacacg atccacacag aagtgttctg cttcaatcac acatttgaca
    30901 cgttcagcag ctaggggcac ctgatcgttg acaatcgcat aatcatactc acgcatgagg
    30961 gcaatttctt ccttggcctt ttcgattcgt tgggcaatca cttctgcact atctgttcca
    31021 cgacctacca agcgatcttg caattcatcc aaatctggtg gtgtcaggaa gataaagaca
    31081 gcatctggaa cctttttctt gacctgaaga gcaccctgaa cttcaatttc aaggaaaaca
    31141 tcgattccct tgtccaaggt ttcattgaca taggtcagag gagttccata gtagttgccg
    31201 acatattctg cgtattccaa catctgtcct tgacgaatca gctcttcaaa ttcttcacga
    31261 gtacggaaga aatagtcaac accgtccact tctccaggac gttgtgcgcg tgtcgtcatc
    31321 gatacagaat attgaaattg gttttcagaa ctctcaaaaa tctctcttct aaccgttcct
    31381 tttccaaccc ctgaaggacc agaaaaaacg attagtaagc ctcggtctgc cattgtgtct
    31441 ccttttagtc aatctgtgaa ataacatttc tctagaataa tggcaaaaag ccagattatc
    31501 ctttacagtc tttctatcta gtgtaacaaa aaagcagtaa tttttcaact gctctttctt
    31561 atttatttag cataatctac tgcacgaagc tcgcgaatca cggttacctt gatatttcct
    31621 ggataatcga gattgttttc aattttctta cgaactttgt gagccaagat tgtgactttg
    31681 tcgtccttga tttttcctgg attgaccatg atacgaattt cacgtcctgc ttgaagggca
    31741 aagctagttt gcactccttc aaagccgtta gcaatttctt ccaaatcatg gagacgcttg
    31801 atgtagcttt caagagactc actacgagca cctggacggg ctgcgctcaa ggcatctgct
    31861 gcagcgacga taactgctat cacgctctca gcttcaacat ctccgtggtg actagcaatc
    31921 gtattcacca caactggggg ttccttgtac ttacgggcca attccatacc gatttcaacg
    31981 tggctacctt caacctcatg gtcaatggct ttcccgatat cgtgaaggaa tccagcacga
    32041 cgggcaagag ccgcattttc accaagttcg ctcgccatga taccagccaa cttagcaacc
    32101 tcaatcgaat ggcgcaaaac attttgtcca tatgaagtac ggaactgcaa acgtcccata
    32161 atcttcatca agtctggatg aaggtttggc gcaccaattt cataggcagc agcctcaccg
    32221 tattcacgaa tcttattgtc aatctcttga cggtttttct caaccaactc ttcgatacga
    32281 gctggatgta tacgaccatc tttgagcaac atttccatag tcatacgggc aatctcacga
    32341 cgaatcggat caaatcctga caaggtcacc acttctggtg tatcgtcgat aatcacatcg
    32401 acccctgtca aactttcaaa ggtacgaatg ttacgacctt cacgaccaat aatgcgtccc
    32461 ttcatagtat cgtctggcag atgaactgtt gagtttgttg actccgctac atattcacca
    32521 gcgatacgtt gcatagcttg aaccaagatg tccttggcca ttttgtcaga acgttccttg
    32581 acctcttgct cagcttcgcg aatgcgactg gcaatctccc tggtcaagtt ttcctctgtc
    32641 tgagccaaga taatatctcg tgcttctgcc tgagacagag caccaatacg ctctagttct
    32701 gcttcttttt gtctttcgac ttcctctaat tgctcttcac gcgcatcaag gtttttcgct
    32761 ctatcagaaa tactttgttc tttttgttca agtgtttgtt ctttactcgt caaattgtcg
    32821 tccttacggt caaggctagt agctctctct gtcaaacgac tttcgatttg tttgagttct
    32881 tgacgttctg atttgaattc agcgtccact tcttcacggt attttctggc ttcttctttg
    32941 gcctccaata gtgcttcttt tttaagagac ttgctttcac gtttagcttc attaacaagt
    33001 aaatccgctt cacgctcagc ttgtccacgt aaattagttg cttcttgttc agcatttaaa
    33061 agcatcaact ccgcagcttc ctgagatgat ttcatcttag ctgagatgct gacatatcca
    33121 atgactaaac caatgatgac ggcaaaaaca gcaatcgcaa gcgacatgat ttccatgttt
    33181 ttacctcatt ttattgttat tccgaatgac atacattctt ttacattcta ccataaaaaa
    33241 gtgattttca caaacctaaa atagaatatg ttttggggaa tttagtctga attttaggat
    33301 tacacttcct tggtttttta aggagataag tcagtgtcgc tatcaaaaag ttccaccgaa
    33361 tttctacaac tatggatttt ctattgttgt gccaaatagt gttccactag attcaaacat
    33421 tttgctttca agtctttgaa aattcacttt aggaaattac agcttatctt caagatcaaa
    33481 tttgtcataa attaactttt tttatttagt tgtatcaatt tat
//
LOCUS       DAVLCS010000023        33410 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLCS010000023 DAVLCS010000000
VERSION     DAVLCS010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33410
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.023"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            <1..413
                     /locus_tag="VXC78_001209"
     CDS             <1..413
                     /locus_tag="VXC78_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0583297.1"
                     /translation="DSRKLSDKRFYRPTFRMYLTNKEILNKLLSYSEDLKHHYQLYNK
                     EPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIK
                     RNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(478..2040)
                     /gene="guaA"
                     /locus_tag="VXC78_001210"
     CDS             complement(478..2040)
                     /gene="guaA"
                     /locus_tag="VXC78_001210"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV0583298.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2182..2880
                     /locus_tag="VXC78_001211"
     CDS             2182..2880
                     /locus_tag="VXC78_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0583299.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(2923..3819)
                     /locus_tag="VXC78_001212"
     CDS             complement(2923..3819)
                     /locus_tag="VXC78_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0583300.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(3828..4763)
                     /locus_tag="VXC78_001213"
     CDS             complement(3828..4763)
                     /locus_tag="VXC78_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV0583301.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4760..5485)
                     /locus_tag="VXC78_001214"
     CDS             complement(4760..5485)
                     /locus_tag="VXC78_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV0583302.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(5569..6204)
                     /locus_tag="VXC78_001215"
     CDS             complement(5569..6204)
                     /locus_tag="VXC78_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV0583303.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(6206..7033)
                     /locus_tag="VXC78_001216"
     CDS             complement(6206..7033)
                     /locus_tag="VXC78_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0583304.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFESNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7055..7195)
                     /locus_tag="VXC78_001217"
     CDS             complement(7055..7195)
                     /locus_tag="VXC78_001217"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583305.1"
                     /translation="MYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEMNEHVGLK
                     WY"
     gene            complement(7241..7390)
                     /locus_tag="VXC78_001218"
     CDS             complement(7241..7390)
                     /locus_tag="VXC78_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583306.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPT"
     gene            complement(7391..7922)
                     /locus_tag="VXC78_001219"
                     /pseudo
     CDS             complement(7391..7922)
                     /locus_tag="VXC78_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            8565..9176
                     /locus_tag="VXC78_001220"
     CDS             8565..9176
                     /locus_tag="VXC78_001220"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0583307.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLKAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9221..9949
                     /gene="rlmB"
                     /locus_tag="VXC78_001221"
     CDS             9221..9949
                     /gene="rlmB"
                     /locus_tag="VXC78_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV0583308.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(9988..10899)
                     /gene="trxB"
                     /locus_tag="VXC78_001222"
     CDS             complement(9988..10899)
                     /gene="trxB"
                     /locus_tag="VXC78_001222"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV0583309.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(10965..11189)
                     /locus_tag="VXC78_001223"
     CDS             complement(10965..11189)
                     /locus_tag="VXC78_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV0583310.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11267..12010)
                     /locus_tag="VXC78_001224"
     CDS             complement(11267..12010)
                     /locus_tag="VXC78_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0583311.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVVQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12010..12810)
                     /locus_tag="VXC78_001225"
     CDS             complement(12010..12810)
                     /locus_tag="VXC78_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0583312.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSVGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(12968..13324)
                     /locus_tag="VXC78_001226"
     CDS             complement(12968..13324)
                     /locus_tag="VXC78_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0583313.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNREAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13318..13848)
                     /locus_tag="VXC78_001227"
     CDS             complement(13318..13848)
                     /locus_tag="VXC78_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV0583314.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGEPQDLSNLLLAPIGTNFEKRVWSYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(13848..14342)
                     /locus_tag="VXC78_001228"
     CDS             complement(13848..14342)
                     /locus_tag="VXC78_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0583315.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14477..14923
                     /locus_tag="VXC78_001229"
     CDS             14477..14923
                     /locus_tag="VXC78_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV0583316.1"
                     /translation="MKTTFSYPKWAEIPNIDPYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            14920..15567
                     /locus_tag="VXC78_001230"
     CDS             14920..15567
                     /locus_tag="VXC78_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV0583317.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     NQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(15588..16169)
                     /gene="pdxT"
                     /locus_tag="VXC78_001231"
     CDS             complement(15588..16169)
                     /gene="pdxT"
                     /locus_tag="VXC78_001231"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV0583318.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16170..17045)
                     /gene="pdxS"
                     /locus_tag="VXC78_001232"
     CDS             complement(16170..17045)
                     /gene="pdxS"
                     /locus_tag="VXC78_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV0583319.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17197..18576)
                     /locus_tag="VXC78_001233"
     CDS             complement(17197..18576)
                     /locus_tag="VXC78_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0583320.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            18870..19793
                     /locus_tag="VXC78_001234"
     CDS             18870..19793
                     /locus_tag="VXC78_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV0583321.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            19853..20458
                     /locus_tag="VXC78_001235"
     CDS             19853..20458
                     /locus_tag="VXC78_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0583322.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20477..21721
                     /locus_tag="VXC78_001236"
     CDS             20477..21721
                     /locus_tag="VXC78_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0583323.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(21944..22201)
                     /locus_tag="VXC78_001237"
     CDS             complement(21944..22201)
                     /locus_tag="VXC78_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV0583324.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22243..24279)
                     /locus_tag="VXC78_001238"
     CDS             complement(22243..24279)
                     /locus_tag="VXC78_001238"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV0583325.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKASLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24491..25408)
                     /gene="glyQ"
                     /locus_tag="VXC78_001239"
     CDS             complement(24491..25408)
                     /gene="glyQ"
                     /locus_tag="VXC78_001239"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV0583326.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(25601..26362)
                     /locus_tag="VXC78_001240"
     CDS             complement(25601..26362)
                     /locus_tag="VXC78_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0583327.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(26635..27477)
                     /locus_tag="VXC78_001241"
     CDS             complement(26635..27477)
                     /locus_tag="VXC78_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV0583328.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERENLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(27591..28982)
                     /locus_tag="VXC78_001242"
     CDS             complement(27591..28982)
                     /locus_tag="VXC78_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV0583329.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTPFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVLENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEHLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(29220..29684)
                     /locus_tag="VXC78_001243"
                     /pseudo
     CDS             complement(29220..29684)
                     /locus_tag="VXC78_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            29838..30815
                     /locus_tag="VXC78_001244"
     CDS             29838..30815
                     /locus_tag="VXC78_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0583330.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSNRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            30812..31894
                     /locus_tag="VXC78_001245"
     CDS             30812..31894
                     /locus_tag="VXC78_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0583331.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     ILRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(31958..32988)
                     /locus_tag="VXC78_001246"
                     /pseudo
     CDS             complement(31958..32988)
                     /locus_tag="VXC78_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         9908 a         7451 c         6022 g        10029 t
ORIGIN      
        1 aggatagccg taaactgagt gataagcgat tttatcgtcc tacttttcgt atgtacttaa
       61 ccaataaaga gattttaaac aagcttttga gctattcaga agacttgaaa caccactatc
      121 agctctataa taaggaacca gagaaatttt tcggactcat tgaggacaat ctaaagcagg
      181 ttcatcctct ttttcagact gtctttaaaa cctttctaaa ggacaaagag aaaatcgtca
      241 acgcccttca actacactat tctaacgcca aattggaagc gaccaataat ctcatcaaac
      301 ttatcaagcg caatgccttt ggttttcgga actttgaaaa cttcaaaaaa cggattttta
      361 tcgctctgaa tatcaaaaaa gaaaggacaa aatttgtcct ttctcgagct tagctgactt
      421 caacccacta cagttgacaa agagcctgat ttcaaagcat tttttgttag tttaaaatta
      481 ttcccactca actgttgcag gtggtttact tgtaatatcg tagacgatac ggttaacatg
      541 atccacttca tttacgatac gtactgagat tttttgaagt acttcccatg gaattttggc
      601 aaaatcagca gtcataccat cgatagaagt gatagcacgg attgcaatcg tgtagtcata
      661 cgtacgaccg tcacccataa caccgactga acgaacgcct gtgttaacag tgaagtattg
      721 ccaaatatcg cggtcaagtc cagctttagc gatttcttca cgaagaatag cgtctgattc
      781 acgaacggtt tcaagtttct cttcagtgat ttcacccatg acacggatag caagtcctgg
      841 tcctgggaat ggttggcgcc atacgatatg gtctggcata ccaagctctg taccaagagc
      901 acgaacttca tccttgtaaa gagtattgag tggttcaatc aattcaaact gcatatcttc
      961 tggaagacca cccacgttgt ggtgtgactt gatagtttga gctgtatccg taccagactc
     1021 gataacatct gtatataaag taccttgagc aaggaatttc acatctttga gcttgcttgc
     1081 ttcgtcatcg aatacataga caaactcgtt accgatgatt ttacgttttt gttcagggtc
     1141 agaaacgcca gcaagtttgt caaggaaacg tttagcagcg tctgctttga caatattcaa
     1201 accaaactta ccaccgagca tgtccataac ttgatcagct tcgcctttac gaagaagacc
     1261 gtggtctacg aagatacaaa tcaattgatc gccaatcgct ttttggagaa gaaccccaac
     1321 gacagatgag tcaacaccac ctgatagacc aagaaggaca cgtttatcac cgacggtttc
     1381 acgaattttt ttgatctgca tgtcaatgaa attatccatt gaccagtcac ctttagcctt
     1441 acaaatgtta agggcaaagt tacgaaggat atcatttccg tatacagaat gacgaacttc
     1501 tgggtggaat tggataccgt aaatgtgttt atctgggttt tcgatggctg cgtatgggca
     1561 gtcagctgat gtacctgtac gaacaaagtc agcaggaatc tcagtaaccg catcaccatg
     1621 gctcatcaaa acagtctgtt catcaggtgt tgattcaaaa agcgctgatg gtgtgtgagt
     1681 tagggttgat tgaccgtatt cacgatttcc agcatcacct gcaggaacaa cttttcctcc
     1741 aagtttatgg gtcaataact gcataccata acagattccc aaaattggaa ttccgagttc
     1801 gaagatttct gggtcaatat caaatgaacc atcttcatat acagaatttg gaccacctga
     1861 tagaataatt cctacaggat tgacttcacg aacttcagca gctgaaattt tatggctttt
     1921 tagttctgaa aaaacaccaa tctcacggat acggcgtgaa atcagctggt tgtactggct
     1981 accatagtcc aatacgatga ttttttctac atcttgcaaa tcagttgaaa tgttgctcat
     2041 ctttttcctt tctcaaaaga aatatctttt ctcaatattc tatcacaaat aagggcgaat
     2101 taccaactaa acaaggcgaa gtttgacttt ttctagttta ttggggtaca atagagaaaa
     2161 gatagaaatg aagtgaaaaa tatgctacct gcttatatga aaatccatga tcagataaaa
     2221 aaggatattg acgagcaccg ttgggctatt ggtgagaggc ttcccagtga aagagattta
     2281 gctgagcagt ttgcggtcag tcgcatgacc ctccgccaag ccgtatctct attagtcgaa
     2341 gaaggcgtct tagagcgccg tgtaggaagc ggcacctttg tttccagtac tcgagtacaa
     2401 gaaaagatgc gagggacaac cagttttact gaaattgtca aatcccaagg taaagttccc
     2461 tctagccagc tcatttccta caaaaaaacc attcccaatg agcaagaagt tgccaagcta
     2521 ggaatttttc caacggacaa tattatccga atggagcggg tccgctatgc cgaccaagtt
     2581 cccctagttt atgaagttgc ttctattcct gaaaaattca ttaaggactt taaaaaagaa
     2641 gaaatcacca gtcatttctt ccaaaccttg caaaaacatg gctatcgtat cggcaaatct
     2701 caacagacca tctatgctcg ccttgctaaa gaaaagattg cccactattt ggaagttgaa
     2761 aaaggacatg ctattcttgg attgacccag gtttcctacc tagaagatgg tactgctttt
     2821 gaatacgtaa aaagtcaata tgtaggcgaa cgctttgaat tttatcttga aaataattag
     2881 attaccacgc aaaaactctc tgtcacggac aaagagtctt ttttattttt ctaagaataa
     2941 atctttcaaa gaaatcaaag ttacagcaaa caatatcatt gccataccaa taaaatcaat
     3001 gggataaaat tgttcattca ttattaagaa ggcaaagaaa accgccgata ttggctcaat
     3061 tgaagccaac aagcttgact tgaccggtcc tatcagactg gctcctttaa ggaaagctgt
     3121 ataggcaaag acagtcccga taaggataat gcctgcaaac gcaaggagaa aatcaagact
     3181 agtcgggata tcggcctgta gaacccctgt aaaaggaagg gcgaccaaac ctgctatgac
     3241 cattcctaca ccaatgacca agctgctccc ccacttttta atcaaggcta tgggtaaaat
     3301 gatatacaga gcataagtca aggcagaaaa gagaccccag aacagaccag caggtgtcat
     3361 ggataactgg tccaactgcc catgtgttgc gatcaggaag gttcctccga tggcgaatat
     3421 gatggaaact atctctccca gtgtcggtgc caccctatcc ttgatacagc tataaattaa
     3481 aattccgaca ggacaaacat actgaagcac cgtcgctgtt cccgcattgg tctcctgaat
     3541 agcagacaga taggcgaatt ggttgagaaa aagaccaatc agagcaaaaa taagaagaga
     3601 cagcaaactc tttctatcct ttaaaaagac cagtatttta tcctttgcag tagcataagc
     3661 caagagcatg agaattccac cagcgattaa aagacgcaag ttggtcaaga ccagagccga
     3721 aattccgtgt gccattaggt attggccact cgttcctgac aacccccaag caataccagc
     3781 cacaactgtt agtaaagtcc cttttaaact atttgacatg tctctcctta ctcttctttg
     3841 cgaatcaagt tcatcacttg attgcggtct aatatccatt gagctctctc gtccttttca
     3901 taggtacgat tcgataggaa aatagtggct tcttgcttct gacgattcca catgataaag
     3961 gtacctgtat agcccgtatg gtctagccaa tctccttcca aattccatgc taaagaacgt
     4021 tccttgtcat ccaaaggaga aaaattttga tttaagtctc ttgcaaaatc atctgctaaa
     4081 tagtgttcta aaaagatttg taaatccttt atagtcgaaa ataaaccagc actcccagca
     4141 tgtctaccca ggagacgagc cttgggatca tgcactatgc ctgcctctac acctctaact
     4201 gttggaacag caagctcaac tggcccaaac ttggtttccg tcattcccca aggtttccag
     4261 acttgatcct ttaaaatcac atccaaatct tgattaaaaa ttctttccaa aataaagccc
     4321 aacagcaaaa aatggacatc cgaataaaga aaggctggct gacttcgtct gttgagatga
     4381 aacatcgctt cctttaattc aggggctgtt aaaagatcac gattaggaat aaaaggatca
     4441 aggtctgttg catgagtcaa gagctggcga atagtgatgt ctggataatc actctcaggt
     4501 aaaaaatcta ttaccagtct atcaatatct aattgaccta tttcccacaa gaaggtacaa
     4561 actgtgccaa ccccaacaac cttgctgaca ctagctaggt cataaactag tcctgcctca
     4621 gtctgcaagc catgctctgg gtcactctgg cctaaataga actctgtcca ttgattgtcc
     4681 ttaaaatacg caaaagaggc tccgggataa attcctgcct cgatttgttc ttctattttt
     4741 ttaataatct tggtccactt catacttctt caaaccacaa ttcaacatta tttctatctt
     4801 tacaaaggaa gaatttttca gacttaggaa taaaatattc agtagactca aacttctggc
     4861 gaagacttgc tatgtctaat tcattgacca agaacttgag catagataag tcccaggtaa
     4921 ccgtattgtc cacagtcaaa tcctgcccct gagctggaat aaaatcaagg gatgccccaa
     4981 tttcagatga ttccaagaaa ctttcgatat cagttgggag atgtaattcc atagaaatct
     5041 caaatttact taaagaaatt gatgccaaat ctgtttgaaa ttcaggcttt tctcctactt
     5101 ctactagact tgctatgtca tcttccgcat gaatcaaaat caaatcatct tctggtgaga
     5161 aaatttcaaa agcgtagcca ttttgacctt tatataatcg atgaatcgaa tctgttttag
     5221 ataagattcc ttcaatttct aagggatttt ccaccttgac aatcaatcta gctagttttt
     5281 ttcttccctc taccttacga gtacgcatac tgggagcttc ttctaaaacc agcttttcaa
     5341 gacccgtttg gtcacctagt gacagaaagg ccgattcttc taacaaggcc ttcattccaa
     5401 gggtttcaat ataaaatgtt tcatttaatt ttctattatt agcttttaaa gtaggaataa
     5461 tccgtacaat ctgatttaca ttcataaatt cctccgtcac tttttatttt aaaggatttt
     5521 agaatttttt acaagatatt atgctcaaat ttaacattat ttagctattt agtaaagata
     5581 gtctttcaag gattttgaca aagcctgata accagcaata ctgaggtgca gtccatcagt
     5641 tgtatattct tttttgagtt ggcctgcttg gtctgtcaaa caatcaaata ctggcacaaa
     5701 ttccacctgc atataggcag atgcaagctc ttgataggct tgattccagt tctgaatttt
     5761 ttcattcgag cggatataga ctgcctgctg gtactcctct ccctcattga caggcaaaat
     5821 ggaaagcaat ttaatctctg tcaatggata atcgcgagca acggattgaa tgatagcttc
     5881 gagattattg agagcctcat tcacaggaac atcctttccg atatcatttg tcccaatcag
     5941 aagaaaaatt ttatctactg ctccaccata tagatgagca tcaaggttct ctagtaacag
     6001 tcctgtctga tagccacgaa ttcctcgatt gacaatcgtc tttgaagtcc caaatagctc
     6061 ctgtagagga taatactcga caatggaatc cccaataaaa agaatgtttg gttctacaac
     6121 agaaatgtga tttaggtgac gatacttagt ttgaattttt tcttgttcct ttaggagcca
     6181 attttctaat aactgtactg ccacttcatt ctcctttttc taaccagttt tccaagactt
     6241 gataaactcc tccttggctg ttggctggtg ctagagcagt cgccacagct ttggctttct
     6301 catcagcatt ttccatcgca taggcaattc cagccatttc aagcatttca acatcatttt
     6361 cactatcacc aaaagccatg atttcttggg atttcaagtc ccagcgcttg agtaattcct
     6421 ccaagcccca tgctttatga atcccagctt ggaggatatc aatgcaacca tagccactgg
     6481 atacagctcg gacacggcca tcaaagagag cattgatttc ttccaaaacc gaactcaaac
     6541 gttcctcacc aacaaccatg ctcatcttga gcacaccacc aaagaggtca gatgttaatt
     6601 catccacaaa ttgcatccgt tggtagaatt tttcaatcat ttctggagtc ataaaacttt
     6661 caagatctgt aaaaatcgta ccttccttga caaaatcacc cttcatcccc gttacaacaa
     6721 actggtcctg acacgctcga cccttgaaat gagtcaaagc cttgttgaca atggcgtcat
     6781 cccatgtctg agcctgaatc aattcattgc tttcaaaaat acgagcgcca ttagcaacaa
     6841 ccagaaccac tcgatccacc aagggactca gtagttgtct catgcggtga atttcattgc
     6901 ccgtcgcaat gacaaaacga atgccccttt gatccaactg atctaaaatc ttttccaatc
     6961 gtgggagatc aagctgacct ctagcatcca gcaaggtccc atccatatct gtcgcaatta
     7021 ccttaatcat catttacttt cctctggatt caagctaata ccacttcaat cccacatgtt
     7081 cattcatttc tttataggct gtatcaattc gttccttagt cgcttcatct aactggtcac
     7141 gatgactgcc atcctctata aaatcttcca aaatataagt ttggtaatga tacaagggat
     7201 atccttctgg tgaaaaggtt ccctttggtg ttcgattgac ctaagtagga tgagctttag
     7261 ctgttccgat agttgttttt ccatccttct tcttgatggt gacatccatg agaacaccac
     7321 gttcagtcca cttagcattc tcttcatctc ccatagattc aatccgttga ttggaaatga
     7381 agttccccat ttaatagaca atgagcttct tatctccatc tttttcaacc gtttcagatg
     7441 gttcaacaac gtgaggatgc cctccaaaga taatatccgc tccccaatcg atcatcttgt
     7501 gataaagagc tttttgttct tcagttggtt ccaatcgata ctcaacaccc atctgaagca
     7561 tgataatggt gatatctgct tccttctctg cccgttcaat ttcagccttc atcttatctt
     7621 cgtttaaatc tgaaagataa cgattatagt cttccttaga aatatactgc tcaattccat
     7681 tgaaaccata ggaataggct aacaatgcaa ccttgatagc attcacttcc ttaatgacca
     7741 gcggagcctg aacacgtggt tcgtgcgtat aaactccgat tggagtgatt ccagctttct
     7801 caataatatc ggccgttgaa ataactccct caagttgaaa taactccctc aagttgcgaa
     7861 tccaaaatat gattatgagc taaatccagc acatgataac ctgcctcctt aatagcatcc
     7921 ataacttcag caggagcatt aaagagaaga taacccgcta aataatgatc cttattaatg
     7981 attccttcaa aatcaccaat agctaaatct gctgcttagt ctccttgctt gagccaagga
     8041 gtcacatact caaaattttc atgaaagtca taggtaccgt cttctttttt agctgaaaag
     8101 aaaagtccat cgtggtagag caaatccccg tgggccataa ttctggcagt tttttcctct
     8161 tcctactcct gagacttttg cttagtcccc tcttgagaaa tagtatctcg tttttgacta
     8221 gtcaagggat tccttggaag ctttcaaaca acaagaccaa gcccttcata aaacgaaaag
     8281 ctaaaccacc ctgatttcga ttttatcttc tttgtatctt cattctccct actttcttat
     8341 gcaagccttt tctttttatt atatcacaga taagtatttc tttcacaatt gaattgaact
     8401 tcccatctat tttctataaa tcctaaatgc cataatgctt tcaattcttg tcattttgtg
     8461 atatcatgta gaggaaatga actaatccac agtggcttat tccaagtata ccacttgggc
     8521 tttggcagta gctaactgca ctaaacataa tataaggaga gaaaatgtct gcaatagaac
     8581 gtattacaaa agctgctcac ttaattgata tgaacgatat tatccgtgaa gggaatccta
     8641 ctctacgcgc gattgctgag gaagtcactt tccccctatc tgaccaggaa atcatcctag
     8701 gcgaaaagat gatgcaattc cttaaacatt cccaagatcc tgtcatggct gaaaaaatgg
     8761 gactccgcgg tggtgttgga ctggctgctc cccagttaga tatctcaaaa cgcattatcg
     8821 ctgttttggt acctaatatt gttgaagaag gcgaaactcc acaggaagcc tacgatttga
     8881 aagccattat gtacaatcca aaaatcgtct ctcactctgt tcaagatgct gctcttggcg
     8941 aaggagaagg ttgcctgtct gttgaccgta acgtgcctgg ctatgttgtt cgccatgccc
     9001 gcgttactgt tgactacttt gacaaagatg gagaaaaaca ccgtatcaaa ctcaaaggct
     9061 acaactccat tgttgttcag catgaaattg accacattaa cggtatcatg ttttacgatc
     9121 gcatcaatga aaaagaccca tttgcagtta aagatggttt actgattctt gaataaagaa
     9181 aatcccgttg caagacgggg ttttgtgtta taatagaggc atgaaaacaa atgatattgt
     9241 ctatggtgtc cacgccgtta ccgaagccct ccttgcaaat acaggaaaca aactctacct
     9301 ccaagaagat ctccgaggta agaatgttga gaaagtcaag gaactagcta cagaaaagaa
     9361 ggtatccatt tcttggacat caaaaaaatc tctctctgag attactgaag gtgctgttca
     9421 tcaaggtttt gttctacgag tgtctgaatt tgcctatagc gagctagatt acatccttgc
     9481 aaaaacacgc caagaagaaa atccacttct attgattcta gatggtctaa ccgatcccca
     9541 taatctgggt tctatcttgc gaacagccga tgcgaccaat gtttcaggtg tcatcattcc
     9601 caagcaccgt gctgtcggag taactcctgt cgttgccaaa acagccacag gtgctattga
     9661 acacgttcca attgcccgag tgaccaacct cagtcaaacc ttagataaac ttaaggatga
     9721 aggtttctgg acctttggaa cggatatgaa cggtactcct tgccacaagt ggaatacaaa
     9781 agggaaaatc gccctcatca ttggaaatga aggaaaaggt atctctagca acatcaaaaa
     9841 acaagtcgat gagatgatta ccattccgat gaatggacat gttcaaagcc ttaatgccag
     9901 tgttgctgcg gccattctca tgtacgaagt tttccgaaat agactataaa aaagtttcca
     9961 gtcatctgat tggaaacttt tttatgatta actatgttct gtaatgaatt tataggcttc
    10021 ttgaccagcg atagctccat ctccaaccgc tgttgttact tggcgaaggt ctttcaagcg
    10081 aacatctcca actgcaaaga taccgtcgac tgcagttttc atgtggttat ctgtcacaat
    10141 ccatcctgcc tgatcttgga tattcaattc tttaacaaaa tcgctaagag ggtccaaacc
    10201 aacatagata aagacaccac cgaaggcttg ttctgtcact tgacctgttt tcacattttc
    10261 aaatacgact gattctactc ggttttcacc cttgatttcc cttactacag aatcccagat
    10321 aaagctgatt ttttcattcg caaaggcgcg atcttgtaaa accttttggg cacgaagttg
    10381 gtcacgacgg tgaacaatgg taacagtctt agcaaaacga gtcaagaaga gggcttcttc
    10441 aacagctgaa tctccaccac caactaccaa taaatcttgg tcacggaaga aagcaccatc
    10501 acacacagca cagtaagaaa caccacgact gttcagttct tcttctccag gcactcccaa
    10561 aggacggtgt ttagaaccag ttgctacgat aactgtacgt gtttcatatg tttggtcatc
    10621 agtcatcact ttcttaaaat caccatggtc ttcgacattt tcaacataac cataaatgtg
    10681 ctccacacca agattttcaa gtggttcaaa catcttttca gccaattcag gtccactaat
    10741 attagcgtat cctgggtaat tttcgatatc agatgtatta ttcatctgac cacctggcag
    10801 accaccttca atcaaagcta cttttagatt gcttcgagca gcatacaagg ccgcagtcat
    10861 ccctgcaggt ccagcaccga taataatagt atcgtacata tagattcctt ctttcttgtt
    10921 gtaactatct ttattctaac tctttcttgt caatcacgca aggattatgc cttgaaaaca
    10981 agaattaaac tcataaccgc aaaggataat actgggacaa ccaagactcc aatcataatc
    11041 atatcataga gatgggcttg gcgagccttg gctgtcttat caactcccga catggctctc
    11101 agaccaatcc aaatccctaa aaaaatcaga acaaggatgg tggtcaagat caaactctcg
    11161 aaatataaag aaaatagttg cagtagcatg atttctctca tttctatctt ttttaaagag
    11221 taaactcagc tagtccaact aactgagttt tcctttatct attatatcaa atataagtcc
    11281 gtttgtaact agcgaagaat tcttttgtcc gctcttcttt aggggtgtgg ataatctcat
    11341 ccggtgttcc agactcgatg attttcccct tatctaagaa gagaatctta tcagccactt
    11401 ggactacaaa ggacatgtca tgactaacca aaatcatggt ttgacctgac ttagcagcat
    11461 ctgcaataga cttttctact tcaccaacca attctgggtc aagggctgaa gttggttcgt
    11521 ctaagagcaa aacatctggt ttcatagcaa gcgcacgcgc tagggcaacc cgttgcttct
    11581 gtccacctga taaatggcga ggataatggt tttcacggtc cgaaagccca accttagcca
    11641 actcttcctt ggcaatctta gtcgcttctt ggtcagataa tttcttgaca acaaccaagc
    11701 cttctttcac attatcaagt gctgttcggc gttcaaacaa attaaactgt tggaaaacca
    11761 tagacaactt acgacgtagg gcaaggattt cttcttgagt gattttagaa aaatcaactg
    11821 aaaaaccatc aatctgaata gagccactgt caggtgtttc aagataattg agactgcgaa
    11881 gaaaggttga ttttccagct cctgaagaac caatcaaggc tacaacttcc cctttttgaa
    11941 tatccaagtc cagatgatcc aagacagtct gtcctgaaaa ggatttgctt aaatttgaaa
    12001 tcttaatcat taacgaaggt ctcctttcac atctgtttgc actgtatcag gtgcagaaat
    12061 agccattttt ctctcgatga aacgaccgag gctttcaatt ccgatattga ccacccaata
    12121 aacaagggca acggagatga agcgttcaaa atagcgataa tcagctccac ctagaatctg
    12181 agcttgggca aagacttcca caacacccac actaaaagct agagatgttc ccttggtcaa
    12241 accgatgagg gaattaatca aggttggagt agctaccacc gctgcattag gaataatcac
    12301 tcgtcgataa acttgcgctc gggtcatacc cagactgcgt gccgcctcaa tctcaccagg
    12361 attaactgag agaatggctg cacgaatggt ttcactagca taagctgcct cattaaaggc
    12421 aaaggcgaca atcgcaaaag ctgcagctgg aatcgcattg atattgagac cagttcccca
    12481 ttgctgattg agggctttca aagccaaagg gattccgtag taggtcaaca tgagttgcac
    12541 caaaatcggt gtccctttta agaaactaac aaagaaggcc tgcaagggat ataaaatctt
    12601 gacacgattg atcttcacaa tggcaaaaag aagcgccaaa accaagccaa aaagggcacc
    12661 accaattgtc aacataattg ttgttggaag ttgttggaca attctaggga ttccatcaaa
    12721 gaccgaacgt aggctaaaca gcttgccatc cggaatcaat tgcatcaagt tttggtacca
    12781 atctgatgct aaaatcgttg taacattcat aaaaacatcc tcttctgata atgattcatt
    12841 ctaccatgct tctgccgtca atgaaattat ttgctacggt cagatacaga ctttgtctac
    12901 ctactagttt atcatacttt gaaacaggga agttatatat tttatctatc aaagagatag
    12961 ataaaaacta tttcagtccc agttcttcat aagattttcg ataaccgatt tgcttaacag
    13021 ttccattttc tactaaaatg ggccgtttta acaacatacc gtcacttgct agcaactcag
    13081 ccgcttctcg gtttgacaaa cttcctacct tatcttttag ccctaattca cggtatttga
    13141 tcccactggt gttgaaaaat tgcttcaatt caaatcctga ggtttctagc caattcaaaa
    13201 tgacttcttg gctaggtgtt tcttccacga tatggacggc tttatagtcc acacctaatt
    13261 gatttaattc ttgttttgct tttttacaag ttgaacattt ggggtattcg ataaattcta
    13321 acatgtgctt ctccttctat tgtttctatc tttaaaatct actccttcat gctccaagag
    13381 ccaagctttc ttttccactc ctgcagcata gcctgtcaga cgcttgcctg ctcccaacac
    13441 acgatgacaa ggtactagga tagaccaagg attgcgtccc actgctccac caattgcttg
    13501 agcagaagcc acttgcaggt cttgagcaat ttgtccatag gtcactgtct gaccataagg
    13561 aattccctgt aaataggacc aaactctctt ttcaaaattc gttccaattg gcgccaagag
    13621 caagttggat aaatcctgag gctcgccttt aaagtaatca tctaagcaag caataactgg
    13681 gtctaaaata ggatgactaa caacttcttc tatcgtttca tctcctagtc ccctctcaaa
    13741 atgcttctgc tcctgaaccc aaattccata caaataatgg tcatcagcta caagtgatag
    13801 aataccaatt ggtgaggagt agagtatttt tacatacttc ttttgcatta tttctttaat
    13861 ttttgatagg ccaagcgttc gccatctact ggcaccttac caacttgttt aaaaccaagt
    13921 ttttcaaaaa tatgttgcat aaccttgttt tcagcatgcg tatctgagcg aaaatcaaga
    13981 taatcaaaac cttcaatcaa gccctctaag aaggtttgag caactccttt tccctgcaca
    14041 tctgctgcca cagcaatacg gtgaaagact agatactctg actctccagc ttgccagttt
    14101 ccctcataaa tagcttcata ggcctcctct ggactcttgg tcacagcagc ataggctagc
    14161 agttctccct cttccaaggc tacgtaggct tgccctgaga taatatcatc gataataaca
    14221 tctgcatttg gatagccatt ttgccactgg tcactaccag catctgctaa acattttttg
    14281 gcatcctcca tcacctgcat gatggcatct acttcatttg gaaaagctaa acgaatttcc
    14341 atcttttttc ctcatttctg actagtttct cccatcatag cataatttaa gtatttctac
    14401 aagcagttaa aacttgactt tgtgtttttg ttattttata atctagttat caaaactata
    14461 taaaaaggag ttgaaaatga aaactacctt ttcctaccca aaatgggcag aaattccaaa
    14521 cattgacccc tatctggacc aggttttgct ctatgtcaat caggtctgcg cccctatctc
    14581 tcctaataaa gacaagggcc taacagcatc tatggtcaac aattatgtga aaaatggtta
    14641 cctgacaaag cctgacaaaa aaaaatacca acgccaacag attgcccgtt tgattgctat
    14701 cacaaccctc aagtctgtat tttctattca agaaatagcc cagacactta atactctaca
    14761 aactcaagca agttcagacc aactctacga tgcttttgtg gactacatga accaaggaat
    14821 tgacccagct aaccctatta tccaaaccag ctgccaaacc gttaaactct atcatcaaac
    14881 tctagactta atcgatcata ctcaagagga ggtaatccaa tgaacactag tcttaaactc
    14941 agcaaacaac tcagttttgg agaggagatt gctaatagcg tgacccatgc tgtgggtgca
    15001 gtcatcatgc ttatcttgct gcctatttca tccatctata gttatgaagc acacggattt
    15061 ttatcctcta tcggcgtttc cattttcgtc atcagtctct ttctcatgtt cctatcatcc
    15121 accatttatc actctatggc ctatggttcg acccacaaat atgttttgcg aatcattgac
    15181 cattctatga tttacgttgc cattgccggc tcatacacgc ccgttgtctt gaccttgatg
    15241 aataactggt ttggctatct gattattgtc atccaatggg gaacgaccat ctttggtatt
    15301 ctctataaaa tctttgctaa aaaggtcaat gagaaattta gccttgctct ttacctgatt
    15361 atgggctggt tggttctggc tatcattcct gccattatca atcaaacgac acccgttttc
    15421 tggagtctca tggtaactgg cggactctgt tatacagttg gagctggatt ttatgccaag
    15481 aaaaaacctt atttccacat gatttggcat ctctttatcc tagctgcgtc cgcacttcaa
    15541 tacatcgcta ttgtttatta catgtaaaaa agttgagaaa ttcaatctca acttttttct
    15601 ttacacatat tgataaagta ctggtgcaag cgcacatcat cagtcaattc tggatgaaaa
    15661 gaacttacca acatattttt ttcttgggct gcaacaattt gattgttcac tgttgctaga
    15721 atttctacac cctcaccaac actactgata atcggaccac ggataaaggt cattggaatc
    15781 ttgccaactc ccttacattc tgcttccgtg tagaaacttc ctaattggcg cccataagca
    15841 ttacgctcga ccaccatatc catagttcct agatgactct ctttctgaga agtgatttcc
    15901 ttagccagca aaattaagcc cgcacaggtc ccaaacactg gtaagccaga tagaatggct
    15961 tctcggatgg gaagtagcat gttctggtca cgtaagagct tgcccatggt tgtagactca
    16021 ccaccaggca aaatcaaacc cgacaagtca ctctgatctt gctgaaaatc atctagattt
    16081 ctgagttcta cactctcgac acctaattga tctagcactt ttgcatgttc tgcaaaggcc
    16141 ccttgcaagg ccaatattcc gattttcatc tattttcctc gttcagccat gagaatttgg
    16201 atttcatttt cattaatacc aaccatggct tctcctaaat cttcagagat ttgagctagg
    16261 atttgaggat tacggaagtt agtcacagcc ttaacaatgg cactcgctcg tttaacagga
    16321 tctcctgact tgaaaatacc tgaaccgaca aagaccccct ctgcccctaa ttgcatcatt
    16381 aacgcagcat ctgctggcgt tgcaacacct ccagcagcga aatttacaac tggcaatttt
    16441 ccatgttcat gaacatattg gaccaattct acagggactt gcaaatcctt ggcagcaaca
    16501 taaagctcgt cctcacgtaa gttttgaatg cggcgaattt cctgattcat catacgcata
    16561 tgacgaacag cttggacgat atcccctgtc cctggttctc ctttggtacg aatcatggaa
    16621 gcaccttcag cgatacgacg caaggcttca cccaaatcct tagcaccaca gacaaaagga
    16681 acttggaatt ctttcttgtc cacatggaaa cggtcatcag ctggagatag aacttcactc
    16741 tcgtcgatat aatcaatttc aatagcctct aaaatctgag cttcaacaaa atgcccgatt
    16801 ctgaccttag ccattactgg aatactaacc gcttcttgga tttccttaat catctttggg
    16861 tcgctcatgc gggaaactcc tccagctgca cgaatatcag ccggaattcg ttccaaggcc
    16921 atcacagctg ccgcaccagc agcttctgcg atacgagcct gttcaggatt ctgcacatcc
    16981 ataataacac cacccttgag catctgtgcc aagtttttat ttagttcata acgattttca
    17041 gtcatttgtt ttatcctcat catttgtatt ggtagctacc ttttcatttt aagtcagaac
    17101 agaatgaagc acaagataaa aaaactataa ttgtatgggg acagattggc taaaaattat
    17161 ctgaccttaa cttaaggcca gatagctcat tcatttctat ttttcagccg taagggcagc
    17221 cattgtgatg tagttgtatg gtttgttgaa gtgtggcaag aagaagaggt ctgtcaatgc
    17281 caatttatca attgtcacat gctcttggat agcaagtgag aacatgtgga ttcccatgct
    17341 aattgcaata tcatgtgaaa ccatttgggc accaagaatt tcacggctat ctttgtcaaa
    17401 gacaatctta attgctactt catggttgtc atgtttcatg aattctggtt tttgaagatc
    17461 gttaaagcct gtttcagttg cgttgtaacc agcagctttc gctttttcaa gagtcaaacc
    17521 agttgaaacc atgtgaagac cgtagattga gataccattt gaaccttgaa caccgattcc
    17581 ttccaattca tgtccacaag cattgtaggc accaacgata ccagtgcgaa cagcatttga
    17641 agcaagagcg atatagcttg tatctttacg agcattgtca taaacagtcg cacagtcacc
    17701 aacagcgtaa acgcctggga tagatgtttc ttgtttcttg tctacaagga aggcaccgtt
    17761 gcggaagagt tcgatcttac catctgcaag ggctgtgttt ggacggaaac caactgcaag
    17821 gataaccata tccacgtcaa agctttcttt gtcagtaatc aagcgttcaa ctttaccgtc
    17881 accttcgatt gctttaacag tttgacctag agccaagcgg atgttgtgat cttccaagtt
    17941 cttcgccatc atttgtgtga agtctttgtc atagtaaccg ttcaagacag tatcaacgat
    18001 atcaacaagg acaacttctt ttccaagacg ttcaaaggct tcagcaagtt caacaccgat
    18061 gtaaccacca ccaacaacgg cgatacggtc gaggtgttgg ctcttgtcag aaagtttatt
    18121 gataacttct tcagcatttt ggtacaattt cacgaattgt acgttttcaa gagttgcttt
    18181 aaattcgcgg tttcctttaa caatttcaac accttcgatt ggtggcaaga ttggtgtaga
    18241 acctgtagcg aaaatcaatt tttcgtatga ttctttgtgc tcttttcctt caacttccgc
    18301 tgtaactact ttgttatcat agtcgattga aagaacaggt gagttcatgt aaactttagc
    18361 acctttagct tccaattttt ctttatcaga atagaacaag ccttcagcac cgtcaatttg
    18421 ttcaccaatc caaagagcca ttccacatcc taggaaagag atgttagagt tttggtcaaa
    18481 tacaacaatt tcgttctcat ttccaaaatt atccaacatg gtattgatac atgctgtacc
    18541 agcgtggtta gcaccgacta caacgatttt actcataaaa atttcctgcc ttcattctaa
    18601 atttacctta ctagtatacc atttaccgtt agcgtttaca aggggggtac tattatttca
    18661 gcatttttta tcaaaaataa ttccccattt atcctgtttt caagcctgat gaattttatg
    18721 agcatatttc ttgacttttt ccaaattttg tttgtgaaaa ttctaacttt atggtattat
    18781 aataacatga aaatgaaatg taagggcttc aatttagatg attatttgat attacaactt
    18841 attttctata agagaaagga gttggtagct tgactcttcg ttcacattct gaacggctaa
    18901 tggggactac tatcactatt tcattagtgg atgagcaagc cgatatcttt ctccaaaaat
    18961 cctttgactt gctcaaagaa cttgaatacc gcttcaacgc caatagtcaa gaatctgagt
    19021 tgatggaaat caattatcaa gcaggaatag cccccgtcac ggttcatcca gacctgtttg
    19081 agctgatttc acttgggtta gagcatagcc tagcgctctc tagccacctc aatatcagca
    19141 ttggtccctt aattcaaacc tggcgtatcg gtttttcaga tgccaaggtc gcgcagcctc
    19201 aagaaattga atcggtgctg cctctaatca atcctcatgg tatcgagtta gattcttcta
    19261 cttctactgt gtttttaaaa cagaaaggaa tgaagatcga tctaggttgt ttagccaaag
    19321 gatacagtgc ggataaggtt gcccaatttc ttaggaaaga gggggtgact tctgccttga
    19381 tcaatctggg agggaatatc ctgaccattg gaaaaaatca ggcaagaggg gataacccat
    19441 ggcaaatcgg gattcaagac ccagccaatc ctaggggaaa tcatttaatg accatccctg
    19501 ttgtcaataa atctgtcgtg acttcaggca tttatgaacg tcacctgacc gtcgatggac
    19561 aagattacca tcacattttt gacagtcaaa caggatatcc tgttgaaacg gaactagcga
    19621 gtctaacaat catctctgat aaatcagtcg atggcgaaat ctggacgact cgactctttg
    19681 gagaaagacc tgcttctatc ctctggcaag tcgaaagttt ggagggcatc gaagtcatcc
    19741 tcatcgataa agaaggccac ctaagctgtt cttcaggaat tcctactcta tagagacaac
    19801 tgtttcaatg gaattttaaa attgtattat gtaaaaagag aaaggaaatc tcatgttaaa
    19861 acttattgct attgttggaa caaattcaaa acgttctaca aaccgtcaat tgcttcaata
    19921 catgcaaaaa cactttgctg acaaagctga aattgaactt gttgaaatca agaccattcc
    19981 tgtcttcaac aaaccagctg acaagcaagt acctgctgaa atattggaaa ttgctgctaa
    20041 aatcgaagag gcagatggcg ttattatcgg tactcctgag tatgatcact ctattccagc
    20101 tgttttgatg agcgctcttg cttggttgtc ttatggtatt tacccacttt tgaacaaacc
    20161 aatcatgatt acaggtgctt cttacggtac gcttggttca tctcgtgccc aattgcaact
    20221 tcgtcaaatc ttgaatgctc ctgaaatcaa ggcaaatgtt cttccagatg aattcttgct
    20281 ctcacactct cttcaagcat ttaacccaag tggcgacttg gttgaccttg atgttatcaa
    20341 gaaattggat gccatctttg atgacttccg tatcttcgtg aagattactg agaaattgcg
    20401 caatgcgcaa gaattgcttc gcaaagatgc tgaagacttt gactgggaaa atttgtaaga
    20461 taggagacca aaaagaatga aatttgttgg acttgttgga tcaaactacg atcaatcata
    20521 taaccgtaag ctcttggaat ttatccgtcg ctacttcaaa ctcaaatttg aattagaagt
    20581 tcttgaaatt gacgaagttc caatgtttaa ccaagatgaa aaatgggatg aaagtttcca
    20641 attacgttat ttatataaca aaattactcg tgcagatggt gttatcattg ctactcctga
    20701 gcataaccac actatctcag cttcactcaa atctgtactt gaatggcttt catacgaagt
    20761 tcatccattt gaaaacaagc ctgttatgat tgtgggtgca tcatactatg accaaggaac
    20821 atcacgtgct caagttcacc ttcgtaaaat ccttgatgct ccaggtgtta atgcctacac
    20881 gcttccaggt aacgaattcc ttcttggtaa agctaaggaa gcttttgata acaacggaaa
    20941 tatcaccaac gaaggcactg ttaaattcct tgaaacttgc ttagataact ttgttaaata
    21001 cgtaggagtc gtttcgaaat tgaaaaaacc aaaaccaatc gaatcagaag acttggattg
    21061 tggaaaacca atcgctacaa ccatcacaga agttgaccct gacgatccag aatgggtaga
    21121 aaaagttgca gcattcactg gtgctgtttc tggtgatacc tatgtcaaat tggaccacgg
    21181 tatcctaaca gttaaccaaa ttgatatgtt cttgaaagct atgccatttg aattgacata
    21241 cgctgacgac aacaaccaat tcctctacta caacaacgct caccaagatc cagacactat
    21301 gttcgctaaa cgtgtaccac ctcaatcagg tagccgtatg tcgactgttc atggttctct
    21361 tccaccagca cgtatgaaga acgtagagtg ggttatcgga acacttcgca acggaaacca
    21421 agaatacgtc cgtacgatcg ttccaggttc tcctgcaggt gttatcaaca ctcacaacta
    21481 ccaagcaatg tactatcctg atggatcata cgctggtatc aatgaaatcg tctttaactt
    21541 ccaaccatgg cttgactggt acctaaaaga gactggtcaa cgtttggtgg gtggtagcgg
    21601 accatttgct cctgctgccg gaggtcatgg agacgccgat gctacttctg gcgcttctga
    21661 ttcaggggat gctggaggcc acggtggtga cgcagacgct acagccggtg caagttacta
    21721 atgatagttt ttaggaacca ttatggttcc ttttttagcg aaaaaagact agcaaacaca
    21781 aactgctagt ctctttgtta tcgtttcatc tatctttgtt aaaagaaaga atacatatac
    21841 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gctgtactta agtacggcaa
    21901 ggtgaagctg acgtggtttg aatttgattt tcgaagagta ttattatgaa tttggatcat
    21961 caagactacg gccatgtaat cctttttcac gttgtacttg gcgtagtttt tctggtgtaa
    22021 catcgtttcc ttcttcgtcc acaattttga ttccttcaat gtggtgacga acagcgcggc
    22081 gataaccttc gatgtactcc tcacgtagtt tggcttgttc cactttttct tctggtgtta
    22141 agccttctgt ttttttcttt ttagcaagct cattgatacg agcaattttt ttcggatcca
    22201 tttcttctcc tctgtaataa gataaagtcc gtttatcaaa ttttatttag tgttaatttg
    22261 gttaaaacaa gcaaacttag ctgctttctt ggttagttgt gacaagattg ccaaacgatt
    22321 ttgacggaca gcctgatctt cagccattac catagtattt tcaaagaaag catcaatgac
    22381 tgggctaagc gcaaagagtt gtttcaattg ctgacttgca ggtcctgata aaacgagtgt
    22441 ttctactgct tctgccaaag ctttttcttg gtcattctca aatagtgctg aatcaaccgt
    22501 agcaacccct tctgccttct cagccaggtt aaaggcacga gaaagtgatt caacagatgg
    22561 tttaaaatct tcttccttgc ttacttctac gagagcactt gctgcttcca acatatctgc
    22621 cacaacaaag tttgaacctg caagaactgc ttctttgata tcttttggag tagagcccat
    22681 catcttatca acacgagcct tgataaagtc cataacctct gctttatttt cataagtcaa
    22741 actgtcaaat ttcaatgcat aaaggctatc aatcagctca tccatagcaa tgtgccaacc
    22801 aaaggcatcc aagatacgaa ccacaccttg agttgcacga cgaagggcat aagggtcatt
    22861 agaacctgat ggaatcaatc ctactgagaa gaaactcaaa atcgtatcca atttgtctgc
    22921 aatggctaga actgcgccga ccttgctctc tggaagttct ccttcagctg atgtaggcat
    22981 gtagtgttca cgaatagcag ctgccaccgc tggagtttca ccagcaagaa gggtgtattt
    23041 ttcacccata attccttgga gttcgtcaaa ttcaccaacc atacctgtca acaagtcaaa
    23101 cttgtaaatg gctgctgcac gagcaaggtc aactgtttca tccactgaca aactagcttt
    23161 ttctgccaaa agtacagtga tttgacccgt acgaatcatg tgttcacgaa gggaaccaat
    23221 cttctcatgg aaggtgacat tgtttaattt ttcaacaaga tctgaaatca ccaatttttg
    23281 gtcttcacgc cagaagaatt ctccgtcttc caagcgggct accaagactt tttcatttcc
    23341 tttgatgaca tttttcaaac gctctgcgtt tccgttacga acagaaatga agtttggcaa
    23401 gagttttcca tcttgatcac gaacaacaaa gtaacgctgg tgttccttca tagaagtcac
    23461 caagacttct tctggaactt caaggtattt agcatcaaaa cttcccatga aggcagttgg
    23521 gtattcaacc aaattcaaga cttcattcag caaatccgca tcaatttcga tacgtacacc
    23581 atgttttgcc tcaatttcct tgatttggtc aacaatcatt tgctcacgtt cacatggatc
    23641 tgcgattaca aactgcttac gaaggtcttc ttcatagctc aatgctgact gaattttggt
    23701 ttctttcccc aagaaacgat ggccacggct cacacgactt cccttgatat caaggaaatc
    23761 caagtcaaac tcttgctcat ccaagagaac agttaaagtg tgaacagggc ggatgtattc
    23821 aaagctattt ccagcccagt gcatgctgac agggaaagtc aatgacttca agacatctac
    23881 aacaccagga acaatggctt caactgattg gccaacttct tccttagtga catagacata
    23941 ttcttcaccc ttaatttcac ggaattcgat atcttcaaca gtcaaacctt tcccacggac
    24001 aaatccttga gctgctttgg tgaagtttcc atcactatcc aaggcaattt tctttgctgg
    24061 tcccttgaaa tcttctgtca aatcagactg tttgtctgat aaaccagtca cacgaacagc
    24121 caaacgacgt ggtgttgaga aggtttgaat ggcttcaaaa gacaggcggt tttccttgag
    24181 gaaggctgcc attttttcgc ctagttgttt ttcacttggt gtgacaacat aggctggtaa
    24241 ttcttcaaga ccgagttcta ctaataagtt ttttgtcatg ttttttctcc gaaaagtatc
    24301 tttttatttt ccagtttgcc ttatgtgatt ggcacgcaag caaccaactt cgttgtttca
    24361 ttgctaaaat tggagccaaa agtctccaat tttgcctagt atccttagtt tcactaagga
    24421 taccttcatc actgcggcaa ctggctcagg gctcactctg ttcgcccatt ttcgtaattt
    24481 gtcactctct ttattctgcg tcttctgcta ggagtttagc tcttgtttct tcatccaaaa
    24541 gtgggtagcc taggcgtttg cgttctgcga caaaggtttt ggctacaaca cgggccaagt
    24601 tacggatacg agcgatatag cctgcacgct ctgttacaga tacggcacca cgcgcgtcaa
    24661 gcagattaaa ggtatgtgaa catttgagaa catagtcata ggcagggtgt accaagcctt
    24721 cttctaatgc acgaccagct tctttttcaa acttatcaaa gttttcaagc aacatttctt
    24781 ggtccgaaat ttcaaatgaa tattttgagt gctcatactc aggctggata aagatttctc
    24841 cgtattttac accatcagcc cactcgatat catagacaga gtctacttct tgaatgtaag
    24901 aagccaagcg ctccaaacca taggtaactt ccgcagtcac agggccagtt gccaatccac
    24961 cgacttgttg gaaataagtg aactgagtga tttccattcc gtcaagccaa acttcccaac
    25021 caagaccagc tgaaccagtt gatgggtttt cccagttgtc ctcaacaaaa cgaatatcgt
    25081 gctccaaagg attgattccc aatttttcca aagactcaag gtaaagttct tggatatttg
    25141 atggagaagg cttcatgacc acctggaatt ggtggtgttg gtagagacgg ttagggtttt
    25201 ccccataacg accgtcagca ggacgacgtg atggctctac ataagctgca ttccatggct
    25261 caggtccgat agcacgaagg aaagtgtaag gactcattgt tcccgcacct ttttcattat
    25321 cataagcctg cataagcata caaccttggt cattccaaaa ttgttgcaaa gtaaggatga
    25381 tttcctggaa agtcaatttc ttagacattg tttactcctt tttatataaa ttacttgcga
    25441 catgagtctg cctcgtcgat catacgaggc aagacgagtt agtactgcgt ctagctcagg
    25501 cactctagtg ctgagcgtgg ggcagtccga ctgtaaggag gtttctgcca ctgacgcagt
    25561 gaaatgtcaa tttcttagac attgtttact cctttagttt ttatatttct ttttcaatta
    25621 atttctgctg aacaaaccaa tctaacaagg gaaaagtttt ttctgtattt gcccataaat
    25681 gataagaatc taagaccgct tgtacactac ctaaattttc taccaactta tctactgtca
    25741 aaaagctgcg ccagtattca taaaaaatac ttgcatagtt cttatcataa gtcgaagaac
    25801 caaaatcatt caatgaatgc caaccatact tcttctgaaa aagttctacg agagattgat
    25861 tacaaatttt ttccgcttga aattcctctt ctgtcaagaa atacttgcga ctaatatatt
    25921 caaccatccc ctcttcgaac cagatataag agtcataacc atcaaaatca tctaaaaaat
    25981 gctccgacca atgagctaac tcatgtccta caatctgtaa gaggaaattt tcagataaag
    26041 aatgatagtg actttctatt gcttgagttt gctgagaaca ctcgtagtcc atcaattgat
    26101 acaaatacaa ctctttccaa acagctaaat caggcgccat aaccattcgt ctattatttg
    26161 tataggctgg aacagcgctt tccctaataa tctgtgtagc agcattaaaa tctgaccaaa
    26221 taacggcttg cggtaaatca cagactgcaa gttcattctt taaaaaagat tgataatctt
    26281 tcaacttttc agtatttctt actacaaaat cacgaaatgt agctagttga ctatcgtctt
    26341 ttacaagata aaggttgtcc acggctctcc tttctttcac acaatagact gaataagcaa
    26401 aagaaccgcg tccgacaatc ctaggttgat ttaacctagg ggcgtcagaa acgcggttcc
    26461 accctaattt attacttcat tgtttttgaa aatactacag aaagcgccag ctcattattt
    26521 tgccctactt ggctcccact atcccaagct cgcttgaaga acgccataag actttctttc
    26581 ctgctgacta ttatatcaaa aattagaata atgtacaatt ctttttatga ttttctagaa
    26641 atccacatca tcaactcgtg gagcacccga ttgaacagca atcgttttta agttttctct
    26701 ctcctcatga ctcagttcaa ttccaaagca atcaagatta gcttgaatac gagaggttgt
    26761 gacagatttt ggaagtggta aaaatccttc tgccaagctc caggccaagg ctatctgagc
    26821 aatcgatttt ccgtgatttg ctgcgatttc ttgcacttgc ttgctatcaa atagttctcc
    26881 ctgaccaaaa ggcccccaag cttccaataa aattcccttt tcacgacagt aagctacgac
    26941 ttgatcttga tacacacctg gcgccaagcg aacttgattg accgcaggaa cgatagttgc
    27001 agtttcaagc aaggcatcca aatgatgggg aagaaaattg ctaacgccga tagcacggat
    27061 tttcccttct tgatagaggt cttccatcgc tctccaaact tccgcattgc gagttttcca
    27121 tgcgtcattt tctctgagcg gttttgggtt cggccaatga atcaaataca aatccaaata
    27181 atccaagccc agtttttcta tagatttttc caaagcttga cgagtttgct cataggtttg
    27241 ctgactattc caaagcttgg tagttacgaa catttcttca cgtggaactc cgctatcttt
    27301 gattgcttga ccaacacttt cttcattctg ataaatcgcc gccgtatcaa tatgacgata
    27361 accagccttc aaggcttcta acactgcatg ataggcttct tctccatcct tagccttaaa
    27421 agttccaaat cccaatactg gaatttctac tccattattt aattgatagg tattcatatg
    27481 cttctccttc tattttattc atcaattata gcataagaca ttttttaagt agtactatct
    27541 tctgtaaaaa ataagtctgt caaatatcta acagacctat tttttcttgc ttattcatca
    27601 cgactatagt acagctcatg agcttttagg cgagtattga gcatctctgg tatggtcaca
    27661 aaggtataac cttgattttt caaatgctca atgacccttg gcaaggcatt gactgtcgga
    27721 ctgtgaatat catgcatcaa aacgatagag ccgttagcta cttgatgctg aatttctgtc
    27781 aaaatagatg cttcattttt actcttccag tccagactat ccacatccca catgataaag
    27841 ctcaaatcca agctattgcg aatatcatct gtaatagcac cataaggtgg acgcatgagt
    27901 ttagaactag aacccagcac tttagttagc acatcctcag tatcagtaat ctgcttttta
    27961 gcttcatcaa gagagagttg cgagagaatc ggatggctcc aactatggtt tccaacaaca
    28021 tgaccttcag attttatcct cttcaccaag tcctcattcc cagaaacatt tttcccaagc
    28081 acaaagaaag tcgctttaat atcatattta gctagggtct ctaatacctg cggggtcgtt
    28141 gctggatttg gaccatcatc aaaggttaga gcgacaactt tttgatattt cttatcaaag
    28201 taagattggt acaaggccgc atctttttcg agtaagtacg aagattggat aacatcaaag
    28261 aaagcagata ctggcaaggc tatctcttct aaattttcaa gcacaggact tggataaagg
    28321 ataatctgac tatccttgta atcaaaattc catgcagaca agtcttggtc agagaagttt
    28381 tttacaatct gctcactctg gtcttgctct atttttttat cctctatgaa gggggtcaac
    28441 tcttttatca gctgttcctt agccttacta gcatctgaaa acagttggtc aagtgtaaaa
    28501 ggttgcccat cttctgttaa gtgaaccttt cctagactgg tcttttcagt ctcttcaacc
    28561 ttaaaagcaa ctaaatcata gatttgtttg gtcacattac gattaacgac tccctttaaa
    28621 cctgactctt cttgctctgt atagtagaaa acaagattgt ccttactttc tagcttgtcc
    28681 ttaacatctt gatttatcaa ctccctaaca gaggaaatca ctttctcccc ttggagagga
    28741 taataggcaa tcacttcggc ttgcccctga cgaaaatgct ccttctgatt tccctcactc
    28801 aattgatcat ctttctcttt tttgagcgat tcaatctttt gctcaaaact tttttgctgg
    28861 tagatcttaa aagcaataaa tccgcctaat aggcaaatag aaattgctaa aataccaatc
    28921 aaagccaata atacatgtct cgttttcccg tgtctgccac gtcctagtct acttttattc
    28981 atatttatat cataacaaat ttgagcaata atttcaatga tacaatttgg caatccacaa
    29041 ttcctctagc aagccaaagc atcttacatc aactccaaca tccgtatctg tagagattat
    29101 gtagttttct atctatggaa tttctagtag attgaagcta gaatagtaga cctatacttc
    29161 taaaacattg ttagaaatcg atttgattgt cctgatcgat ttgtcctgtt cttatttcat
    29221 tttactataa aactatgaga agctaggtca tctgagaagt aattactatc gacaattgcg
    29281 atagcgtata ctggtgcgat gtgtttgtag ctctggtggg tatcaccttc acgttggcga
    29341 attttttcta ggttttgatt aacctgactg cacagataag cccataggcg attgatgaaa
    29401 aaattctgat gatgaacctg aatttcgatg ataacttgga ttccattatc taactccgcc
    29461 aagacgtcta tactagtata gaaatcctgc gctgagtagg gcatggaagg caagacgtga
    29521 atgttacttc cctccaaaat cgtcacattt tttgctggca agtccagcat atcgcggata
    29581 aattgacaag tgatttctgg attgctgaat atttttttag caaccaaatc attagttggg
    29641 ctgatgcccg gatgtctgag aatcctcctt ctattatagc acatttttaa atctaggttt
    29701 gctagattct atgcttctat ctatttattc ggaaaagaaa gctaatagct tatttgaaat
    29761 tttctcctct ctgttggata gtcccgtcta tctatgttat aatgaaagaa ggatttaaaa
    29821 tcggaaaagg agtatttatg ctaaaattag gtgtcatcgg aactggcgct atcagccatc
    29881 atttcataga agcagcccat accagtggag aataccaact ggtcgcaatc tattctagaa
    29941 aactagaaac tgcagcaacc tttgcttctc gctatcagaa tatccaacta ttcgatcaat
    30001 tagaagtctt cttcaaatct tcttttgatt tagtctatat cgccagtcca aactccttac
    30061 attttgctca ggcaaaagct gccttgtctg ctggtaaaca tgttattctc gaaaagccag
    30121 ctgtcactca accacaagaa tggtttgatt tgattcaaac agctgaaaaa aataactgtt
    30181 ttatctttga agcagctcgt aattaccacg agaaagcctt tactactatc aaaaactttt
    30241 tagcagataa gcaagtgtta ggagcagatt tcaactatgc caaatactct tccaagatgc
    30301 ctgacttgtt gactggacaa acaccaaatg tcttttcaaa ccgttttgct ggtggagccc
    30361 tcatggattt ggggatttat cccctctatg ctgctgttcg tctttttgga aaagccaatg
    30421 acgcgactta ccatgctcaa cagcttgaca atagcattga cctaaatgga gatggtatcc
    30481 tcttctaccc agactatcaa gttcacatca aggctggaaa aaacatcact tccaatcttc
    30541 cttgcgagat ttatacaaca gatggaacct tgactctcaa cacgattgag catattcgct
    30601 cagctatttt taccgaccac caaggaaatc aagtccagct tcctatccaa caggctcctc
    30661 atacgatgac tgaggaagtc gctgcatttg cacacatgat ccagcaacca gatctgaatc
    30721 tctaccaaac ttggctgtat gatgcaggct ctgttcatga gctactatat accatgcgcc
    30781 agactgctgg cattagattt gaggcagaaa aatgaaaacc aaactaccga ctgaatggca
    30841 agaactgagt gaccaactcg gtttccaaga attcaccccc attcaaactc aactatttga
    30901 gccccttctt gctggagaaa acctcctagg agtgagccaa accggaactg gtaagaccct
    30961 agcgtatctc ctaccaagtc ttctcagact acaaaagaaa aaagcccaac aactcttgat
    31021 tctagcacca aacacggaac ttgctggaca gatttttgat gtatgtaaaa cgtgggcaga
    31081 agctatcgga ttgactgctc aactcttcct ttcaggttca agtcagaaac gacaaattga
    31141 acgccttaaa aaggggccag aaattctgat tggaactcct ggccgtatct ttgaactcat
    31201 taaacttaaa aaaatcaaga tgatgaatgt ggaaaccatc atcctggatg aatttgacca
    31261 attactagat gattctcaga ttcactttgt agaaaaaatc actcactacg cacctcgtga
    31321 ccaccaactg gtctacatga gtgccacgac caagtttgat caagaaaaga ttgtgccgaa
    31381 tacacgcact attgatctct ctgatcaaaa attggacaat atccagcatt tctacatgca
    31441 ggtagaccaa cgtcatcgag tggatatact acgaaaactg gctcatgtag aggatttccg
    31501 tggtctagtc ttcttcaata gcctgtcaga ccttgggaat gccgaggaaa aactacagta
    31561 tcgtgatata ttggctgttt ccctcgctag tgatgttaat gttaaattta gaaaagtcat
    31621 cttagaaaag tttaaagata accaactaac cctgcttctt gcaactgacc ttttggctcg
    31681 tggaattgat atcgatagcc tagaatgtgt cgtaaacttt gatattccta gagatagcga
    31741 aacctacaca caccgtgctg gccgtactgg ccgtatgggc aaggaaggat atgttattac
    31801 tctcgtcact catccagaag aaatcaaaaa acttaaaaag tttgcaagta tccgagaaat
    31861 tgtcctaaaa aaccaagaac tctatatcaa ataaagcccc attgctctat acacatccag
    31921 tgtatggagc ttttttataa gcaattcaat tttatactca tctgctttca aaaagcattc
    31981 tattccatct ccgattaacg atggacttta tcacctcctt ctccagtcct tgtatgacat
    32041 cttggagttg attcatgaca tcttccaaag ttcgaaaggc tttattctta aatccacgtt
    32101 tacgaatctc tttccacact tgttcaatgg gttcatctct ggtgtgtatg gaggaataaa
    32161 ggtaaaatca atattagtcg gaatctttaa ggtacttgat ttatgccata tagcattgtc
    32221 cataacgagt aaaaaataat catctggata agcttgtgaa agctcttcta aaaagacgtt
    32281 catccactca gtattacatc caccagctat taagaaaaat gattcgcctg tatggggcat
    32341 caacagctcc ataacaatag cgaaattctc gtatatagtg actatggaca tgtggaccta
    32401 ctcctattgg agaccaacaa gatcccagtt tactgattct accgaaacca gcctcatctt
    32461 ggtacatcaa gcgaacctta tgaaaaggtc tactggtttt aaagcgcttt cttgtcttct
    32521 tgaattgaga ttttattttt agacgcgaca atggtttgag cgtctgcttt cttaggatgt
    32581 tctggacgtg gcataatatt tcgccaacca tggtgcttca acagttgata gaaggcatca
    32641 cgtgtgtagg aacgatataa gcctgaaata aggtattgta acaaattctc ctgcctctgt
    32701 agccttcaaa tggcgggcaa gaaaggcttt ctcttcctca actgtcatat atgcatggtt
    32761 acgaccacca cgtgtttctt gaaggagaga gtcgagtccg aactcctcat atttttttac
    32821 atttcgccaa atcgttgttt gattacagtc taaaagatct ataatctctt tataagattt
    32881 gcccatcaga cgaaatagaa cgatttgaag gcgtttatga tatttagctg tacgaaagtc
    32941 ttttaaaagt gttttgatgg tttggatttc ttcttcagtt gatttcatat tactattgta
    33001 taatgctttt tgatttgagt ctagtattat actcttcgaa aatctcttca aaccgcgtca
    33061 gcttcgcctt gtcgtataga tgttactgac ttcgtcagtt ctatctacaa cctaaaaaca
    33121 gtgttttgag cagtctgcag ctaactttct ataacaaaat gaaataagaa caagacaaat
    33181 caatcaagac aatcaaatcg atttctaaca atgttttaga agtagatgtg tactattcta
    33241 gtttcaatat attatagttt gctctttgat tttcattgag tattagttca atatctaaaa
    33301 aaagaggctc tataatattt gtagtgggta aatcccctat agatattatg gagcctattt
    33361 ttgtgtagaa aaaaagtccc atatgaccta taatgaaaag cgacaaaacc
//
LOCUS       DAVLCS010000024        32653 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLCS010000024 DAVLCS010000000
VERSION     DAVLCS010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32653
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.024"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(340..1029)
                     /gene="rplA"
                     /locus_tag="VXC78_001247"
     CDS             complement(340..1029)
                     /gene="rplA"
                     /locus_tag="VXC78_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV0583332.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1237..1662)
                     /gene="rplK"
                     /locus_tag="VXC78_001248"
     CDS             complement(1237..1662)
                     /gene="rplK"
                     /locus_tag="VXC78_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV0583333.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(1785..2501)
                     /locus_tag="VXC78_001249"
     CDS             complement(1785..2501)
                     /locus_tag="VXC78_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV0583334.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2519..2980)
                     /locus_tag="VXC78_001250"
     CDS             complement(2519..2980)
                     /locus_tag="VXC78_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0583335.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(2982..4019)
                     /locus_tag="VXC78_001251"
     CDS             complement(2982..4019)
                     /locus_tag="VXC78_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV0583336.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDTRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSEAVS"
     gene            complement(4117..5442)
                     /gene="brnQ"
                     /locus_tag="VXC78_001252"
     CDS             complement(4117..5442)
                     /gene="brnQ"
                     /locus_tag="VXC78_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV0583337.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5613..5705)
                     /locus_tag="VXC78_001253"
     CDS             complement(5613..5705)
                     /locus_tag="VXC78_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0583338.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5748..5900)
                     /locus_tag="VXC78_001254"
     CDS             complement(5748..5900)
                     /locus_tag="VXC78_001254"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0583339.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(6060..6638)
                     /locus_tag="VXC78_001255"
     CDS             complement(6060..6638)
                     /locus_tag="VXC78_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV0583340.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6692..8092)
                     /gene="pepV"
                     /locus_tag="VXC78_001256"
     CDS             complement(6692..8092)
                     /gene="pepV"
                     /locus_tag="VXC78_001256"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV0583341.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGFKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8105..8710)
                     /locus_tag="VXC78_001257"
     CDS             complement(8105..8710)
                     /locus_tag="VXC78_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV0583342.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            8881..9681
                     /locus_tag="VXC78_001258"
     CDS             8881..9681
                     /locus_tag="VXC78_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0583343.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(9865..10698)
                     /locus_tag="VXC78_001259"
                     /pseudo
     CDS             complement(9865..10698)
                     /locus_tag="VXC78_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
     gene            complement(10688..12535)
                     /gene="uvrC"
                     /locus_tag="VXC78_001260"
     CDS             complement(10688..12535)
                     /gene="uvrC"
                     /locus_tag="VXC78_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV0583344.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEIYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12575..13276)
                     /locus_tag="VXC78_001261"
     CDS             complement(12575..13276)
                     /locus_tag="VXC78_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV0583345.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13355..14587)
                     /gene="murN"
                     /locus_tag="VXC78_001262"
     CDS             complement(13355..14587)
                     /gene="murN"
                     /locus_tag="VXC78_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV0583346.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14592..15812)
                     /gene="murM"
                     /locus_tag="VXC78_001263"
     CDS             complement(14592..15812)
                     /gene="murM"
                     /locus_tag="VXC78_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV0583347.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(15924..16703)
                     /locus_tag="VXC78_001264"
     CDS             complement(15924..16703)
                     /locus_tag="VXC78_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0583348.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYMALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16772..18433)
                     /locus_tag="VXC78_001265"
     CDS             complement(16772..18433)
                     /locus_tag="VXC78_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0583349.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18608..20830)
                     /gene="recJ"
                     /locus_tag="VXC78_001266"
     CDS             complement(18608..20830)
                     /gene="recJ"
                     /locus_tag="VXC78_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV0583350.1"
                     /translation="MITPTYEWQFALQVENADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSIPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPYRDLFIAFGGHAGAAGMTLEVEQLSDLSQILEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEVSFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMMDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21107..21866
                     /locus_tag="VXC78_001267"
                     /pseudo
     CDS             21107..21866
                     /locus_tag="VXC78_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21906..22670
                     /locus_tag="VXC78_001268"
     CDS             21906..22670
                     /locus_tag="VXC78_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0583351.1"
                     /translation="MISLFGLVAAKPVQANTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLTFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22683..23360
                     /locus_tag="VXC78_001269"
     CDS             22683..23360
                     /locus_tag="VXC78_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0583352.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFCIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23370..24029
                     /locus_tag="VXC78_001270"
     CDS             23370..24029
                     /locus_tag="VXC78_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0583353.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKIKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVPVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24325..25515
                     /locus_tag="VXC78_001271"
     CDS             24325..25515
                     /locus_tag="VXC78_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV0583354.1"
                     /translation="MKSIKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKRVHFYYSFRGEENAVYLDLLRDYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCSPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25836..26717)
                     /locus_tag="VXC78_001272"
     CDS             complement(25836..26717)
                     /locus_tag="VXC78_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV0583355.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26858..28186)
                     /gene="vncS"
                     /locus_tag="VXC78_001273"
     CDS             complement(26858..28186)
                     /gene="vncS"
                     /locus_tag="VXC78_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV0583356.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(28183..28839)
                     /gene="vncR"
                     /locus_tag="VXC78_001274"
     CDS             complement(28183..28839)
                     /gene="vncR"
                     /locus_tag="VXC78_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV0583357.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(28888..28971)
                     /gene="pep27"
                     /locus_tag="VXC78_001275"
     CDS             complement(28888..28971)
                     /gene="pep27"
                     /locus_tag="VXC78_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV0583358.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(29151..30530)
                     /gene="vex3"
                     /locus_tag="VXC78_001276"
     CDS             complement(29151..30530)
                     /gene="vex3"
                     /locus_tag="VXC78_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV0583359.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30582..31229)
                     /gene="vex2"
                     /locus_tag="VXC78_001277"
     CDS             complement(30582..31229)
                     /gene="vex2"
                     /locus_tag="VXC78_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV0583360.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31242..32519)
                     /locus_tag="VXC78_001278"
     CDS             complement(31242..32519)
                     /locus_tag="VXC78_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0583361.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9222 a         7490 c         6073 g         9868 t
ORIGIN      
        1 ctctacttct aaaacattgt tagaaatcga tttgactgtc ctgaacgatt cgtcctattc
       61 ttatttcatt ttattataat tgatagtggt cgccccagcc agatacctta tccactatat
      121 aggccttatt atcacgttcc tgttcgtaga gccacgattt cgctatccct tcctctgacg
      181 attcttattt ccagcgtcag acttgggaat cgctattggg ttcaccggta gtaggtgccc
      241 accgaggact tacacctcag atatacgaca tgcccgtcgt acatcaaaaa aagttgagac
      301 atagtgtctt caactttttt acattacttt aactactgat taaagtgagt ttacgtcaac
      361 tttgatacca acaccttgag tagttgtgat agtcaagttt gttacgtaag ttcctttagc
      421 tgtagctggt tttacttttt ggattgtttc gttgaaagct ttaaagtttt caaccaattt
      481 ttcagcttca aatgatactt taccgatgat tgcttgaacg ttacctgcac ggtcagcacg
      541 gtaagtgatt ttaccacctt tagactcttc aactgcttta gcaacatcca ttgttacagt
      601 accagtttta gggtttggca tcaagttacg tggtccaagg acacgtccaa gacgtccaac
      661 aagagccatc atatcaggtg tagcgataac tacgtcgaag tccaaccaac cgtcgttgat
      721 tttagcaaca aggtcatctt caccaacaaa gtctgcacca gcagcttttg cttcttcagc
      781 ttttgcacca cgtgcgaaaa caagaacacg tgaagtttta ccagtaccgt ttggcaatac
      841 cattgctcca cggatttgtt ggtcagcttt tttaacgtcg atgttcaagt tgtaagcaac
      901 ttctacagtt gcatcaaatt ttgcaaagtt agtttctttt gcaagtgcta cagcttcttc
      961 tacactgtat gcttttgtgc tgtcgatttt ctcaagagca gcacgaagtt gtttgctttt
     1021 tttagccatt ttctattctc cttgtaagtg gttcaatcga ttttcatctc ccacgtcact
     1081 tctcgaaatg atgaagtctt gcgggttttc agtctactat ttttctcttc ctacggcctt
     1141 aagctccctt gctgtatcca agtacaagcc tcagtcactt gcctagtatg aaaagcaact
     1201 aatagactgc tgtgagattt tctactgtgt tattgattag tcaacaacag tgaatcccat
     1261 agaacgagca gtaccttcga tcatacgcat tgcagactct acgtttgctg cgttcaaatc
     1321 tggcatctta gtttctgcaa tttcttgtac ttgtgcacga gtaactgtag caactttagt
     1381 tttattaggt gtacctgatc ctttttcaac acctgcagct tttttcaaaa gaacagcagc
     1441 tggtggtgtt ttcgtaacga aagtaaatga tttatcttcg taaactgaga taacaactgg
     1501 aatgatcata ccagcttggt cagctgtacg agcgttgaac tcttttgtga atcccatgat
     1561 gttgatacca gcttgaccaa gagcaggtcc aaccggtgga gctggtgtag ctttaccagc
     1621 agggatttgc aattttacaa gtttttcgac ttttttagcc atttttaaat cctcctttgt
     1681 ggttttggcg gtaattagag atttttacct cccacaagta tgctttacac atacctttcc
     1741 attatacact atttatctaa aaatgcaaga gaaaactttc atttttaatc gacataatcg
     1801 ccgccttcaa agccatagta ctcttccaaa ctgagaccac ttgcagcaat ttctttggct
     1861 tcttttccaa cgtagcggag atgccattct tctgccatgt agccagtctc cttttccttg
     1921 cctttaagat agcgaacaac aaagccatag tcagccgcat ggtccaagag ccactgggct
     1981 gccttttctt cagtaactaa atccccatct gtcccaatca aatcaaaagc aagacccgtc
     2041 tggtgttcac tgtaacctgg gcgtgctgag tagcgatctg ctgcttcctt accatcttga
     2101 ttgacatagt cttggtagag cttagcctga gtttcataac tcctaaaccc actgtattgg
     2161 tcactgattg gatagccctc agcctgcata gctgcgatta gtttgagcaa ctctgccttg
     2221 gctgttggat tttctcctgg attgtaatct tttgacaaag gataacgttt attagctagg
     2281 ataatctcat cgtatttccc ttggatacta taatagctcc ctttattgct aacttctgcc
     2341 tttttctgac tagaagcttg agatttgcta cctacagttc cttccggttg actgctttgc
     2401 tccgtttttt gagtgttttc ttcaactttg gttttttctt gcgaacaagc tgcaagggtc
     2461 aatgctagta aaccagataa aatgacatat ctttttttca tttctttctt cctctctctt
     2521 aggccaaata cttctccaat tcatgagata agattttaat catctcttcc agctctggcg
     2581 attgtacttg gcaatcttct gccgccattt cttcccaggg cacccaccag actgggccac
     2641 ggccattcaa accgtgactc ttcatatcac ctgctcttcg gggaaaaaga tgccaatgag
     2701 cgtgggcatc gccatttcct aggagttcaa tattcatctt ttcagcctca aatgctttgg
     2761 cgactgcttc ttggactaaa ctcatttcct ctaaaaagcg aagttttaca gaagtttcca
     2821 tatgatggag ttctgtgaca tgatcttttg ctaaaaataa ggtatagccc ttaaagtatt
     2881 ggtagtcacc aataacaaca tagcctgttt ctagttcttt tacaaagtag ggattttgcc
     2941 cagctttaat gagttcgatt ctctgacaga ttaagcacat tctatgatac cgcctcgctc
     3001 ttaagataag catcaaccat acgctcagtc gctattactg aatcgatgtg ggtgcgctca
     3061 taagagtgac tggactcaat accagctcca agaagtgcat gcttgacctc tgcacctgct
     3121 gacatcgctg ctgaagcgtc cgatccgtaa aatggataga tgtcgagctt aaatggaata
     3181 tcttgctctt tagccaaggc aaccaagtgt tgacggaagt catagtgata aggacctgaa
     3241 gcatccttga cacagataga tactgtgtac tcatctgtct gctggtcatc tcccatagct
     3301 cccatatcca cagccagata ttctactacc tgagcaggaa tgttagaatt agcaccatgt
     3361 cctacttctt caaaaactga aaaagcaaaa tgagttgtta ctggcaattc aatcttctct
     3421 ttcttataaa tacgaagcag gttgagcaaa atcgctgcgc tgaccttatc atccaaatga
     3481 cgagacttga taaaacctgt atcagtcaca acagttcgtg tatcgaagct gataaaatca
     3541 ccgacctcaa tcccaagagc acgagtttct ttttcattgc ttacttttac atccaaacgc
     3601 acttccatat tgtcctgcgt gcgttctgca gttcctgcat ccttgtagac atggcaagaa
     3661 gtttggtgga tgaggatggt tcctgatacc ttttgacctg tgctagccac atgaacggta
     3721 cagttttcac cttcaatcat gttccaagga aaaccaccga tacggtccaa tttaagacga
     3781 ccatctggtt tgacagcacg aacaatagca cccagcgtat ccacatgggc agtcacatag
     3841 cgatgttgct catcattttg acctttgatg gtcacattga caccaccctt agctgtgcga
     3901 actggctggt aaccaaaacc ttctagagtc ttgactaaat aattcgaaat ttcacgagtg
     3961 aagcccgttg gcgatgcgat ggctgtcagt tctttgatat attctactgt ttgattcatt
     4021 tcttcacctc tttcgctacc tattataaca catttatcat cggataaaaa aagaaaatca
     4081 ctcctgtaga cttggctaca aaagtgattt aagtgattat tccatttcaa aaacatcgct
     4141 ttcttgcttg tttggtagaa ccaatgagag caagattcca acaatggctg gcaccaacca
     4201 tgggagagat gccttggcaa aaggaagaac gctaacaaga tttgcaagaa actcaacctt
     4261 aaacgagctt cctagtacgc ttgcaatggc aataactgta accacagcaa ttgtcaactg
     4321 catacctggt tttgaaaggg caacaaattt gttgacaatg acaatcataa cgatagcaat
     4381 cgtgattggg tacaagataa ccagtactgg aattgagtac ttgataatcg catcaagacc
     4441 caaattggca atagcaaatc caatcaaggt aaaggctgtc gcataaacct tgtagctgat
     4501 ttgtgggaag cgctcattaa agaactcagc tgttgacaca atcaaaccaa cagtcgttgt
     4561 gaagcaggtt acggtaacca tagctgcaag gaagagttga gctgttgagc caaagatttc
     4621 ttgagtggct tgtgacaaga tgtaaacacc tggtgttcca cccttcatcg cttcagctgg
     4681 tactgggaaa tgatttccaa gaaaacctaa accgatgtaa agagcgctga aggcaagggc
     4741 aacaacgata ccaacaaccc aaatagttga aatgtattct ttcttacttg aaaatccaag
     4801 ttgtttcaag gtttgaactg cgattacgct aaaggccact gaagcaaggg cgtccaaggt
     4861 attgtaacct tctaggaaac ctgtaccaaa ggcagaagct tgataagcag ctgaagcagc
     4921 ttgaggactt gttccaccat atttgatagc tcccagaacg accaagataa caatcaaaat
     4981 tgcaaagact ggcgttaaaa cacgtccaat gcggtctaag atttttgatg gattaagcga
     5041 aatcaaatag gctgccgcaa aatacagaac cgtaaataca atcaagccaa gtcctttatt
     5101 tgcatccgac aaaagggggc taatccctac ttcgtaagct gttgtagcag tacgtggggt
     5161 agcaaagaat ggaccgattg acaagtaaag aactgagagg taaagagtcg caaaccaagg
     5221 cgctatcttc gttgaaatct cgtagatata tcctttagga tttagcgttc caataataag
     5281 ggtcaagacg gcgataccaa cgcctgaaaa gacaaaacct gcgatggcag gaagaaaatg
     5341 ttctccagat agagcaccta gagaaggcgg aaaaatcaag ttccccgcac caaaaaatat
     5401 tccaaacagg agcaaacctg ttagggtacc ttttttagcc ataaaaatct ccttcatatt
     5461 tataaaatac tgacctagta taccacgatt aggagtctga aaaaagcatc acgaggcaaa
     5521 tattaaatgt tttcaatttt cttaaaaata agaattatct aaaaataaaa ctctcctacc
     5581 cagtccacac caagtaggag aaatgcaaaa ttttaaagtt cttcaaaggc taacatgcca
     5641 ccctggacat tgataacatt ataaccttgt tctaacagga attggcaagc acgcgccgat
     5701 ctcattccag atttgcaaat aatataatgc aagcgatctt tgtccaatta atcataacta
     5761 tcagccaatt gactaagcgg taggttgtgg gcacattcta aatgaagagc tgcaaactca
     5821 tccacttctc tcacatccac tagagaaagc tggtcgtttt ggtaaagctg gtaaaatgcg
     5881 tcaaaggcta tttctttcat tctttttctt ctaatactct tcgaaaatct cttcaaacca
     5941 cgtcagcgtc gccttaccgt gcgtatgtta ccgacttcgt cagttttatc tgcaacctca
     6001 aagctgtact ttgagcagcc tacgactagc ttcctagttt gctctttgat tttcattgac
     6061 tataaaatgg ttttaattct ttttttcaaa tctggcacta cttctgcctc aaaccaagga
     6121 tttttggcca tccagatttg atttcgtggt gatgggtgaa ctagcggaaa ataggctggc
     6181 agatagtctt tatagtgttt caccctctcc gttaccttcc cactgatttt ctcctgtaaa
     6241 tagtaggctt gggcatattg cccaatcaag agggttaact gaatatcagg caattcctgt
     6301 aagagctgcg gatgccattt ttctgcaaaa cctgtacgag gcggaagatc acccgacttg
     6361 ccatgtcctg gaaagtagaa atccataggc aaaacagcaa aataacctga attgtaaaag
     6421 gtatcttcat ccacacctag ccagtcccgc aagcggtcac cacttttatc tttccagtaa
     6481 aggcctgctt cttgagtttt aagtcccgga gcctgaccga tgatattgat gcgagcagtt
     6541 tttggcgctg caaagagagg ctcaatgcca cgctctgtat agctggcatt ctgtgaatcc
     6601 gccatgatag cctgtttgat tctttcgatt tgagacatct actttccctc caaaaagaag
     6661 tccaagcata agatctcaga cttctatcgt tttatttgat caattcgtaa atagcttcgg
     6721 catagattgc tgctgctcgg aagagatcgt ccaaggcgat aaattcattg gcttggtgca
     6781 tggtatcaat tgagtctggg aacatagcac cataggcaac tccgcgctct aacaagcgac
     6841 caaaggttcc accaccgatg acttgttcat gacctttaaa gccagtttgt ttttcataga
     6901 tattcaacaa ggtttgcaca agtggatctt ccattggcac atagtgaggc gtgtgaccgt
     6961 gttcagacag gctaacagaa acaactggca agttttcaag gattgacttg atttgttctg
     7021 gacttgttcc ttttggatag cggatgttga gggcaatggt attatcagca cttgtttcat
     7081 cgaagcggaa gacgccggca ttcatagaaa gagcacccat cttttcatcc acatgagcaa
     7141 tcttaagatt ttcaccctca tgatcgttca agagaatttt acctgcgatg tcaaggtagt
     7201 ctttggctgg accagcaaag ccaaactgac tgaggaagag ggcaaggtaa gttgcgccat
     7261 tgacacctga agcaggcata gcaccgtggg ctgatttacc aatgatcgtc accttgtatt
     7321 tgccagcttc ttcttggagt tctcctctaa gtttgtgttc tgcaacaaag gcatctagtt
     7381 tagcttgcaa gtcagccaag tcacctgaaa cgactgctgt tgctgattct ggtaccatat
     7441 tttcacgtaa accacctgta aagctgtgaa gacgggcaac acctgtattt tctcctgcaa
     7501 agtggaggta ttccgtgata tttccttttt caccattgat gattggaaat tcagcatctg
     7561 gtgagaaacc gaaatctggt ttggcaagtc ctacgtgctc aaagtagtag tccatgtctg
     7621 cccagcctga ttcttcgtct gttccaacga tgaagcgaac tttcttagaa gttggaagac
     7681 ccaattcttt gatgattttc aaaccatagt aacaagctgt tgtaggaccc ttatcgtccg
     7741 aagccccgcg cgcataaagg cgaccatctt tgatagttgg tgtgtaaggg tctgtgtccc
     7801 aaccgctacc agcaggcacc acatccatat gggcaaagat tccgagaact tcttctccat
     7861 caccaaactc aaaatgtcct gcatagttat caacattctt agttgggtag ccatcgcggt
     7921 ctgcgatttc aaggaatttc tccaaggctt ttactggacc aggcccaaat ggatgctggg
     7981 catcagcctt gctgtcatca cgttctgaat tgatttccaa aaggctaaac aagtcagcca
     8041 agaggtcttc tttgcgtttt tctacttctg ctgtaaaatc aattgctgtc attttttctt
     8101 ctttctatct tttctcgatg atttcatcta ctggcaagcg gtagcttggt tccaattttt
     8161 cgtctgtata acccactgtg atcaagagtt ctgggcggaa acggtcttcg atttccaaaa
     8221 cttcattaac ttttgatttg tcaaaaccaa gaataatgtt agaaccaatt ccttggtctg
     8281 tcaatgcaag aaccaagttc atggcaacca aacctgcatt gagagctagg tagtcgctga
     8341 cttgttgttc attgtagcgt gcaaattcag ctggcaaatt tttcatgaag tattgaagtt
     8401 gttcttctga gaaattgtta gcaccaccaa ctcgggcaat cttacgagcg cgtttggcaa
     8461 ggtctgtatc tgtaaatagg gcaatggtta caggtgctga tgatacctgc tcaaagtttg
     8521 aaccataagc caactttgcc agttcagcat ttttctcacg aacaactaca aatttccaag
     8581 gctggctgtt gtgggcgctt ggcgccaagg ttgcaatttc gatagccgta cgcacatctt
     8641 ttggatcaac aggcttatca gtgaaatgct tggtcgcatg acgtttttta tttaattcaa
     8701 gaaatttcat aatcgatttc cttttctaat tctactgctt ccattctacc ataatttgaa
     8761 agagcttgca gggatttttc atgattaagt ttttctatca cagacataaa agatatatat
     8821 tggtttatca ggaaagtttc tgataaacta gcaagtactt tacatttgaa tggagacagt
     8881 atgaaaaaat ttagcctatt actagctatc ctaccatttt tggttgcctg tgggaatcaa
     8941 gctacaccca aagagactag cgctcaaaag acaatcgtcc ttgctacagc tggcgacgtg
     9001 ccaccatttg actacgaaga taaaggcaat ctgacaggct tcgatatcga agttctaaag
     9061 gcagtagatg aaaaactcag cgactacgag attcaatttc aaagaaccgc ctgggaaagt
     9121 atcttcccag gacttgattc tggtcactat caggctgcgg ccaataattt gagttacaca
     9181 aaagagcgtg ctgaaaaata cctttactcg cttccgattt ccaacaatcc cctcgtcctt
     9241 gtcagcaaca agaaaaatcc tttgacttct cttgaccaga tcgctggtaa aacaacacaa
     9301 gaggataccg gaacttctaa cgctcaattc atcaataact ggaatcagaa acacactgat
     9361 aatcccgcta caattaattt ttctggtgag gatattggta aacgaatcct agaccttgct
     9421 aacggagagt ttgatttcct agtttttgac aaggtatccg ttcaaaagat tatcaaggac
     9481 cgtggtttag acctctcagt cgttgattta ccttctgcag atagccccag caattatatc
     9541 attttctcaa gcgaccaaaa agagtttaaa gagcaatttg ataaagcgct caaagaactc
     9601 tatcaagacg gaacccttga aaaactcagc aatacctatc taggtggttc ttacctccca
     9661 gatcaatctc agttacaata acactcttcg aaaatctctt caaaccacgt cagctttatc
     9721 tgcaacctca aagctgtgct ttgagcaacc tacggctagc ttcctagttt gctctttgat
     9781 tttcatattg agtataagat atattaaaag cgatgggatc agccaatcgc ttttttagtt
     9841 tgcattggtt attttaggaa actcttacaa aaaatcaaaa aaattcttca catcctctac
     9901 atacctatgc ttttctatta agcttgctaa tagttccaga ttgtgcctct gatagttatc
     9961 ttcacgacgt agttcttcat acatttcgat aaagggaaaa cccttggatt tggcaaattc
    10021 taactcagcc tcgtaatcat aagcgacttt acgaaatagg atatttacca attccccatc
    10081 ttcaacctct atcacggcat actgggcacg gtgatttttt aacgcctccc aattaaaata
    10141 gggcatgcca atcgaccctg gattgatgat ttgttgccct tgactaccat aacgaagcaa
    10201 ctacttgtga acatgaccat aaactgccac gtccgtttcc gcatctagca gttggtcaaa
    10261 tttctctgta tcattctcaa ctagcaagtc accaccatag tttttgtcag gtaaattatg
    10321 agagatagaa aagcgcaatc cgtcaatttc tttcttttcc agcaaaggca agcttcgtag
    10381 ccagacaatc gttgcaggat ccattcgctc catcaaatac tgtgtcatac gcaagagctg
    10441 aacttcctgt gggtcttcta agccatattg cccatctaaa gcctcaagga cacaatcatc
    10501 ccaattgcct cgaacacttg ccgtgatagg aagttccttt aacagagcga ccaagtcatt
    10561 tgcacctgga ccagggagga aaatgtctcc catgagccaa tattcactgg ctccttgagt
    10621 tttagcatct gcaatcactg cttctagcgc cgtcgcattg ccatgaacat ctgataaaat
    10681 tgcgatttta tggtttattg tggtttcctt ccgtttggta atctactctt tcttccgcca
    10741 cttgaagcaa gatttctgtt tcctgcgggt tcaacttggt ttgcacagcc tctgctactg
    10801 ctcttggtac tccaacttcg acaatctcat ccacactggc ttccttgatt ttggtcagag
    10861 acttgaagtg cctcatgaga ttttgcttgc gtttaggtcc cagaccatca atcccatcca
    10921 attgagatga gaaagaattt ttggagcgca gttggcggtg gaaggtaatg gcaaagcggt
    10981 ggacctcatc ttgaatgcgt tggaggagga aaaattcctg agaattgcga gacaagtcca
    11041 ccacttccag cggatctcca aagagcaatt catgggtttg gtgcttatca ttcttttgca
    11101 gacctgcaat tggaatatcc aagcccagtt cttcttggat gacttgctta gcaatattga
    11161 cttgaccttg ccccccatca atcacaatca aatctggagg agtcaaagcc tcacgctgta
    11221 ctcgaccata gcgtctgcga atgacctctc gcatactggc atagtcgtct ggcccgacta
    11281 cggtcttgat tttatactta cggtaatcct tcttactagg cttgccgttg acaaagacca
    11341 ccatggctga aacaggacta gttcccatga tgttggagtt atcgaaggac tcgatgcgaa
    11401 ctggggttgg gatttgaagc aagcgtccta gattttcaat agctccttgg gtcttctcga
    11461 cagatttctc tagcaggttg aacttctgct ctaggctaac acgggcattt tttatagcta
    11521 aattgaccag ctgctttttc tctccacgtt gaggcttaag aatcttggaa tccaccaagg
    11581 ccttgacagc ctcttcgtca atatcttgcg gaatcagtac ctcattggga actagatggg
    11641 atttttcttg atagaattgt cctacatagg tcaaaaaatc ctcatctgga tcattgaagt
    11701 aggggaagag attgacatcg cgctcgatga gcttaccctg acggacaaag aaaacctgca
    11761 cacacatcca gcccttatcc acatagtagc caaagacatc gcgattttgg agatccttag
    11821 ccatgacccg ttgcttggtt cgaagcgttc caatagcctg aatcaggtca cggtattccg
    11881 ccgcacgttc aaactccata gtctgggctg ccgctgccat tttgcccttt agctcatcaa
    11941 tgattttgtt atcctgccct ttcagaaaat cagaaacctc ctgggccata gacttgaaat
    12001 aaatctcatc cttcttacag atggtgtggg ccatgcattg accgatatgg taataaaaac
    12061 agaccttaga gggcgggttg gtacacttac gaaaagggaa tatccgatcc agcaaccgct
    12121 tgatttcatt ggctgccccc acatcgggat agggtccaaa ataaagacct ccgtcctttt
    12181 tgacctgacg agtgataatc aagcgtggat agcgctcatt ggtgattttg atgaaaggat
    12241 aggacttgtc atccttgagc atgatattgt acttgggctt gttttccttg atcaggttga
    12301 tttctaggag aagtgcctca atattagact ccgtaacaat aaattcaaaa tccacaattt
    12361 cagacaccag agcctctgtc ttggtatcat gacttccacg aaaataggac cgtactcgat
    12421 tacgcagatt tttagccttt cctacataga taatggtgcc atttttatcc ttatgaatgt
    12481 agcaaccagg gctggtcggc aagagctcta gttttgattt aatcaagttg ttcatagttc
    12541 cattatagca aaaaaagtag ggaaagatag taccctactc actagtctca tatatttttc
    12601 ggaggtttgc aacatcctct tcctggatac cataaaagga acctgctggt tgcatgacag
    12661 acttctcatc tgtatggtcc aagccaatcg catgacctaa ctcatgttct gccgtatgga
    12721 caaggcgttc ataggagtag ccatagtatg gattggacaa ataataatga ttcaaccgca
    12781 ccgttacgga caagaattgc cctgttaaga gattagtttg actttccgcc tctcctgcca
    12841 caggagtgcc tccgtcgttc atctccgtag ccgtaatatc cgccttacta gactcagtca
    12901 cgagttcaaa gttaaaagca ccagtttgat tccagttctg gattgcttct aaataagcct
    12961 cttgaaagcg tgaatccatc tgcggatcca ggtaaatacg agcagaggcc tgtgcccacc
    13021 ttccttcaga atgctggtga ctatctgtct ggcttaactt aggcagttgc cctgttttct
    13081 cccattggtc aatactttgt tgaccaattt ttactgaccg ttctgcttgc tttagcgctc
    13141 cttgaaaatc tccgttcaga taccagagaa gtccgaaagc aagcacacat aagagcacaa
    13201 ctatccaaac cagacgccaa aacaaacgcc acacaaaaga aaagaaagcc cctatcaaac
    13261 gaaaaagcca gcgcatgtct ctccaccttt ctagcaaata agaattattt tactaaaaga
    13321 agctaaaaga aatctaaata ctgacttttt catcttaacg tcctactatt tttttgagta
    13381 actggatagc tttgtatttt aaaggagatg gatggtaacg gaaagtacct gctttgcgta
    13441 caatatagcc attaaaattc tgtttaaaac gcaaaacacc atcacttcca tcaaaaatcc
    13501 cttgaatgcc taggaagttg tatttaggta ttccacgttt tatgctttcc aacataacat
    13561 atttttgaag cagggcaggg gcatagaact tattaaactc agtgtaggaa ccactaaaga
    13621 gataagtcgt ttcctgaggc atataaacaa ataaactccc agctaaaaca atatcttctt
    13681 ctccatattt ttcaatcaag tctcgcgctt ctgcttttcg aacttcaaac gtttcaaatt
    13741 gactagaata ttctctcagt tgattttgtt ttttctcaga atgaggattt ttactcaaat
    13801 caagtcgcaa cttgtccaag ttttcttcta gtttactttg ttcaccttgc aatttgctca
    13861 tatagtccga aaaatttaag cttgctatga gaaactccgc ttgttctcca aaagtatcat
    13921 aaaaatgctc ataatattct aaacttttat cactatattc tctacgttca gaggtttctt
    13981 ttgttatatt cttaaaaatc gatagttctt cacgttttaa ctttttcaac cgaatgccaa
    14041 aggtttcagc ctttttcacc aagggtttac cctttttgct aaaactttta agcaaactct
    14101 tttcagttaa ttcagttaaa tctttatagt ataaccaatc tggttctcca cctgggtaac
    14161 ctgttgttaa gccatcaaat tgataaccta aatcagtcaa accttgaata atactttttt
    14221 tctcagcatc tattggatta ccttggctat caaaagtttg ataagtttca taaggtttta
    14281 caagcaactc taatacacca ttttgcttgg catattcttt taactctgca taaaaaactg
    14341 gaagagcatc ttgttgggta taaattggcc ccgaattgag ttccatatgc agaccaccca
    14401 gcatgggcaa gctataaacc agagctgcaa cttgaatttc tccttcttgt ttcaaagcaa
    14461 gataaacaat tcgagcccct cttttttcta gcaaatcccc catctggaca gattgcataa
    14521 aggaacgaga agaaacctga tcagaataag tctgaaactc ttctttcgtg agtgttgtta
    14581 gtgccatata cttactttct atgttttttt cttaatgttt tacggaaatc aagagcaagt
    14641 cttaacagag gatagagagg atgagtgggc attgtaaatt cacccaagta ttcttcaatc
    14701 gttggattaa atttttcctt aaaatgataa agtccaccat tgagagagtt ttcaacacca
    14761 cctaaatttt gccagaccat acctcgctca aaggcatagc gagccgtttc ataccatgtt
    14821 aaaattggtg cattgtaacg tttaaaatca tcatccatac cagcatatat attaacagag
    14881 gtagtaccaa attccaaact caaagtagcc gctaaaggaa ctctcgcttg acctacatct
    14941 atatattcct gcaagaaggt caattcctct aacaaacgtt ctttttcctt cttctgcgct
    15001 tctacttttg aagttcgagt cgactcagta aacgtctctt ccaaggctct atttttcgct
    15061 aactgttctt ctaattcttg cgaacgttta gaaacatcca aggtggccaa ggtgatatag
    15121 gccttgtcct taaaattatc taacaatttt ttataatagg cttcattcct caaatgaatc
    15181 tcttttcgct tctcagtttt tttcatcaac tccgaaaatg aatctaatag ttccagtcca
    15241 ccatattgaa tctcaagccc tttgtttcgt gctgttcgaa tagcctgttt tgttgacttg
    15301 gaaagtttat cttcttcaaa attttccttg tatattttcg cctgaatacg aggttgaatg
    15361 gtgtctccca tttcctccgt ttttcctgac caccttactc ccatttgttg caaactatca
    15421 ataatagcca gattttcagg aaattctgtc ttttcctgat tgattaaact ttgagatagg
    15481 caaatacttg ggtcaaaagt cacaaaaacc gctctcttac tgcgagcata ggacttaata
    15541 gactgaatgg caaaattcaa gagttcttta tccccataat ccaatatagg tcctcttggg
    15601 atgtaaaaca ttttatagcc tagcggaaga gttctaatca aaatactagc tgtcgccagt
    15661 aatttttctt ccctgtaaac accaaacttc tcatgttgcc aattagactt aacttcctcc
    15721 caagcactac tttgtaatac attggctaat tcatgttctt tgacaaactg atcatattct
    15781 aatgtgggaa tgccaatttg ataacggtac atttcctact ctctttcctc cagtatttta
    15841 ttactattct actactttcg tttgaaaagt ctagtgaaaa catattttat tttagttcta
    15901 ctccccctat gctgaagttc aaactaagtc agtctctctt ctaatttgaa atcaattggt
    15961 agggttgtta aaaaaacttc caattgtttt tcccagtagt accactcgtg agttccagca
    16021 ctatggctat aggtcacatc aaaacctagt tttttgagat ttttcactgc gagattattg
    16081 gcttcgtaca agaaatcctg ttcgccacac cacgcccaaa gtttggtctt tttatccgat
    16141 tttttagcca gactttcaag agaataggga ctagttgtcc agtctctaat ctctccaaaa
    16201 acacctctcc agtaggctgg acttcccaga ttttgacttt caggagaaaa gttttgaaag
    16261 ctgagggcac ctgaaaaact agctgcatga gaaaaacgat ttgtcgtaag agccagtttg
    16321 aagcagccgt agcctcccat agaaagacca gcgataaagg tcttttcacg cttgctagtc
    16381 atattaggga agaagcgttt cagaacctgt ggcaattcct ctgctagagc catgtagtag
    16441 tcaaaaccat actgggtatc ggtgtaccaa ccattgctgg tattgggcat aacaacgatg
    16501 agattagttc ctcgaagcaa gcgttctaca ttggtccgct taagccaact attatgattt
    16561 ccagacatcc cgtgcaaaag gtacaagacg ggaatatctt cacactctgg ttcttccact
    16621 cgattggcat cagggtagag gacattcacc ccccactcca tatccaatac ttgtgagtaa
    16681 tactcgattt tcattactgc catgattttc tccttctatt tttctataag aaaaagccga
    16741 aactcgactt tctctctgtt tatttcaacg attattttgc ttccatgact actggtaaaa
    16801 tagctggacg acgcttggtt tggtcaaaga gatacttggt caaattatct cgaaccttcc
    16861 ctttaagatc tgcccagtca aagtcatctc cttgaagata ctcttctacc gtttggttaa
    16921 tcaattctga actttcacgg agaatatcgc gactcttctt gagataaaca aatccgcgcg
    16981 tatgaacacg agccctagcc acaattttct tctcacgacg gttgactgta atagccacga
    17041 tgaaaattcc atcctctgac aagaccttac ggtcacgaag aacaacattt ccaacatcac
    17101 caatggcatt cccatcaatc aagatatctc ctgctgaaac cgatccagct ggaacaaagt
    17161 ctccattctc gtaagccatg gtcgtcccct ttttaggaat gaagatgcgt tctggcaaca
    17221 tcccaactgc catggcagcc ttagcgtgag catccaactc acgatactcc ccttggacag
    17281 ggaagaggta cttaggttgc aaaagattga tcatcagctg caaatcacgc acatttccgt
    17341 gccctgatac atgtaaactt tgggtaatca atttgacaac cccacctgcc tgataaatca
    17401 tattttccac acgcgcaaca aaggcttctt tagcaataga cggagccgta gcaatataga
    17461 ccaggtcccc atccttgatt tctacataac gatggcgacc aatcgacatc ttacgaagtc
    17521 cattgatagg ttcacccata cgacctgtct caagaataat caactcatgg tcttcaaagc
    17581 gagacatatc tttaggctta atcaagagaa tttcgttggc taaagacaac ttcttaagac
    17641 gaatcgctgt gcggacgata ttttcaatat caaatcctgt caagacgata cgtcgacctg
    17701 ttttatccgc agcgtcaaaa atctgctgaa tacgagaaag attactggaa acagctgcaa
    17761 cgatgatacg accttcccag tcagcaatag tttgggtaat ttcatcccta acttcacttt
    17821 cactagccac ctgaatattg ctgtctgcat tggccgaatc actgaggaga gccaggacgc
    17881 cgtcacgacc aatctctgcc aaacgagcaa aatcagttgc ataagattca ctagccgttt
    17941 ggtcaaattt gaagtcacct gtataaacga tgcttccttc cgatgtcttc aagacaattc
    18001 ccagactctc tggaacggag taagtcgtag ggaagaagga aaccactgtc ccaccaaaat
    18061 caatctccgt attctcatca atgacatgga aatcattaaa tttcttaacg gcatcatttc
    18121 ctttgacaaa gagctttgcc aactcaatgg tcaactcaga cccaaataca ggaactttag
    18181 cctctgccaa gagataaggt agagcaccaa tggcatccgc atgcccgtgg gtcaagaaaa
    18241 ccccagcaat acggtcgcta ttttcaaaaa ggtaatccat gtttggaatc accacatcga
    18301 cccctaattg ttcattttca ggatatttta accctacatt caaaacaaaa atggactctc
    18361 caatttcagc aatgtacata ttttttccat tctcacgcac accaccaagt gttgttaaac
    18421 tgatattact catttttcct ccaaaatctt agtttatctt gattataggg caactctacc
    18481 ctcttattct aaaagttcta atactttcag ccgaatcttt tcctaccatt ataccatttt
    18541 tttgatgatt ttcaaaatga aggtctgttt tcaaaaaaga gttgatttcc caactctttc
    18601 ctaacttcta ctctttttcc atcaaaaaat cataaatttc ttgcaccgta cccagcgcca
    18661 tcatttcttg gtctttaacg gtttgtttga gattttggta aatttgactt tctcctatct
    18721 cccgctttgg cgcctcttta ttgactgtca tcacaccatc ttttatcgtc acaaagccta
    18781 gttcttcaaa tacttgaatc atcttgacca gcaagatttg ttgaatatta agatatgcag
    18841 ccaaatcttt cagcttgtag cgaatatcaa actctgggaa ctggtaaata gtcttgtaca
    18901 atttggcaaa ctgatctcta gtcccataac ctgtcagata ataggccttg tcaatatcat
    18961 ttttgaaata gacagcagag aaatgctgtt cctgaaaaat ggtcttcagc tgagtaatat
    19021 cctctggaat gttttttacg acaacagctt cactagccgc aagatttggc agttctccag
    19081 gaaaatccaa gactggaaca ccttctggca agactgcatt ttttccacga atgttaaaaa
    19141 gttgaacacc ttccactcgc gcatccatca tcatcaactg gagggcagtt tggccgttcc
    19201 attggttgac agacaattta accgctaact ctagattctt ggtttgagaa aactctgtcg
    19261 cccatctgcc ttgaccaaag gctaccactt caaaactcac ctcacccttg gaaattttca
    19321 gctttagatg ggcattacct gcccccatag tacgagcact ttcgacctga aaattcttga
    19381 tataaaaaat aggtttctga ttatccattc caaaaggagc taaacgttca aaacttttga
    19441 ccgtttccaa gctaagtgcc tccaaatcca actcttcatc taggtttaac ttattcttgc
    19501 caccagcatc tgcacctttt tcacgaacat aatcttccaa aatctgagat aaatctgaga
    19561 gttgctcaac ttccagcgtc atacccgctg cacctgcatg acctccaaag gcgatgaaga
    19621 ggtctcgata gggatccaga gcttcaaaaa tatcgaccgc ttccacacta cgagcactgc
    19681 ccttggcacg accgtcttct atattaagaa caatgactgt ctgtcccaat tcttccaata
    19741 aacgaccagc cacgattcct agaaccccag gattccagcc ttccttggcc aagacctgaa
    19801 ccttcttctc aggatccacc atggtcttgg cttcttcata gatagactga acgatttcct
    19861 tgcgctcttc gtttttctgg tgaatcataa gggcaatctc atgcgcttcc tcatcatcaa
    19921 atccagtcaa caaatcaatg gcaggattgg gatcatccaa gcgacccaag gcattcaaac
    19981 gaggagcaat ctggaaacca accgtttctt ctgttacttc gttagcagca atcccagcca
    20041 tgtccagcat ttcttgcaga ccaatgcgct gggtatgacc caacatttcc agaccatatt
    20101 gaactaagat acgattttca tccgtcagac tcaccatatc tgcaatagtt ccaatagcga
    20161 ccaaatcaag caattccact tgcacttctt ctaacagggc acaagccaac ttgaaagcaa
    20221 ctccacaacc agccaaatat ttaaaaggat aatccgcatc tggatgttca ggatggacaa
    20281 tagcataagc atctggcagg gtttcaggta tggaatgatg gtctgtcaca atgacatcta
    20341 ctcccataga ctgagccaat gcaatagcct catgaccagc aaccccattg tccaccgtca
    20401 caatcaagga aattccttct tgctcgataa agtatttata aacactagca ttagggccat
    20461 agccatcggt aaaacgattt ggcaggtaaa ctcggcactc cgcaccaagt tgttccaaac
    20521 tttccttcac aatagaagcc gaagtcatgc catccgcatc atagtctcca taaacgagaa
    20581 tattttcccc ttcttcaata gcctgacgaa tccgctccac tgccttgtcc atatcatgga
    20641 gcagataagc atcatgtaag tcctccaagg aaggttctaa aaacttcttc agactttctt
    20701 ggtcctgaat ccctctctca aacaataacc gagccacctc aggacccagt ccagccttct
    20761 tggctatctt tgtaaaatcc gcattttcta cctgcagggc aaactgccat tcataagtag
    20821 gtgttatcaa aaagacatcc actctttcta agaattctat tgcttcatta taacatgatt
    20881 tagacgtttt ctctatccag attgcttttt tataacattt tatagtatat tgaaactaga
    20941 atagtacacc tctacttcta aaatattgtt agaaatcgat ttgattgtcc cgatcgattt
    21001 ttcctgttct tatatcacta tagtgaattt tttcagatat gatttgacaa gaacattctt
    21061 ttatcgtaga atcatgttat aaaatctaac acaagggaga tctctcatgg ctttagtaga
    21121 atttaaaaac gtcgaaaaat attacggaga ctaccacgca ctccgcaaca tcaatctccg
    21181 ttttgaaaaa aggacaagtt gttgtcctgc ttggaccttc tggctctggg aagtccactc
    21241 ttatccgtac gatcaatggt ttagaggctg ttaacaaagg aagtctccta gtcaatgggc
    21301 accaagttgc tggtgccagc cagaaagatt tggtacctct tcgcaaggaa gtcggcatgg
    21361 tttttcaaca ttttaacctt tatccacaca aaacagtgtt agaaaacgta acacttgcac
    21421 ccattgaagt tctaggaatt gataaaaaag aagctgaaaa aaccgcccaa aaatatctgg
    21481 aatttgtaaa tatgtgggac aagaaagatt cctatcccgc catgctatct ggtggacaaa
    21541 aacagcggat cgccatcgct cgtggtcttg ctatgcatcc ggaactcctc ctctttgatg
    21601 aaccaacatc tgctcttgat cctgagacta tcggagatgt tctagcagtt atgcagaaac
    21661 tggcgcatga tgggatgaac atgatcatcg ttacccacga aatgggcttt gctcgagagg
    21721 ttgcggaccg cattatcttt atggccgacg gagaagtttt agtagatatg acagatgtcg
    21781 atagcttttt tgacaatcca agcgaacctc gtgcccaaca attcctcagc aaaattatca
    21841 accacgaaag tgacaaagtc aaataaggag gcgcctatga aaaaaaattc tttttatcag
    21901 cattattgat tagccttttc ggccttgttg ctgccaaacc agtccaggct aatactagta
    21961 tcgcagacat tcaaaaaaga ggcgaactgg ttgtcggcgt caaacaagac gttcccaatt
    22021 ttggttacaa agatcccaag accggtactt attctggtat cgaaaccgac ttggccaaga
    22081 tggtagctga tgaactcaag gtcaagattc gctatgtgcc ggttacagca caaacccgcg
    22141 gcccccttct agacaatgaa caggtcgata tggatatcgc gacctttacc atcacggacg
    22201 aacgcaaaaa actctacaac tttaccagtc cctactacac agacgcttct ggatttttgg
    22261 tcaataaatc tgccaaaatc aaaaagattg aggacctaaa cggcaaaacc atcggagtcg
    22321 cccaaggctc catcacccaa cgcctgatta ctgaactggg caaaaagaaa ggtctaacct
    22381 ttaaatttgt cgaacttggt tcctacccag aattgattac ttcccttcac gctcatcgta
    22441 ttgatgcctt ttccgttgac cgctctattc tgtctggcta cactagtaaa cgcacagaac
    22501 tactagatga tagtttcaag ccatctgact acggtattgt taccaagaaa tcaaatacag
    22561 agctcaacga ctatcttgat aacttggtta ctaaatggag caaggatggt agtttgcaga
    22621 aactttatga ccgttacaag ctcaaaccat ctagccatac tgcagattaa ggaggacacc
    22681 ccatgacaga tttatcatct tggacagcct attttcagga ttttggacaa tttttcaatg
    22741 gtttcctctt tactcttgcc ctagcgattg gatcctttat cctcgccatg gtcttaggaa
    22801 tcttctttgg tgccatgtca accagtaaac gtccaatttt acgcatttta gctcgcatct
    22861 ttgttgaatt ttaccaaaat actcccctct tggtgcagtt tgttattgtt ttttatggcc
    22921 tacctcttat cagtgaccat atcatcatga ttccaattta ttggacagcc gttctctgcg
    22981 tgggactcta tcacggcgct tatatcgctg aggttattcg ttcagggatt cagtctattc
    23041 ctagtggtca gatggaggcc gccttgtcgc aaggttttac ctatatcagt gccatgcgct
    23101 tgattacctt gcctcaggcc ttctgcatca ttctacctcc attgaccaac caaattgtta
    23161 acctcatcaa gaacacctct actgtagcta tcatctctgg agtagacttg atgtttgtga
    23221 ctaagtcttg gtcggctctc aacggaaact atatcccagc ctttttaggt gctgctcttc
    23281 tctactttgc cctatgcttc cctgttgccc agtttggtcg caagatggag caagccaaca
    23341 aaaaagccta ttcactttag gaggttacta tggaatctat tttagaagtt ttaaccccag
    23401 ataacctagt ctttatcttt aaaggatttg gcttgaccct ctatatttct ctgattgcca
    23461 tcatcctctc tactatcatc ggtacggtgc tagctgtcat gagaaatggc aaaaatccta
    23521 tcttacgcat tatttccagt atttatatcg agtttgtgcg caacgttccc aaccttctct
    23581 ggatttttac tatctttttg gtgttcaaaa taaagtccac accagcaggt attacagcct
    23641 ttactctctt tacatcagca gccttggctg agattattcg aggcggtctc aatgccgtag
    23701 acaagggaca atacgaagca ggaatgtcac aaggcttcac ctcagcccaa atcctctact
    23761 acatcattct cccacaagcc atccgcaaaa tgctaccagc catcatttct cagtttgttc
    23821 ccgtgattaa ggataccagt ctcctctact ctgttatcgc cctacaagaa ctctttggag
    23881 ccagccaaat tctcatgggc cgttatttcg aaccagagca ggtcttcagt ctttacatcc
    23941 tgattgccct catctacttc agctttaacc tagcaatttc tagcctgtct catatgctag
    24001 ccaaacgttg gcaacaagct gcagaataat actcttcgaa aatctcttca aaccacgtct
    24061 gcttcacctt gccgtatata tgttactgac ttcgtcagtt ctatccacaa cctcaaaacg
    24121 gtgttttgag cagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa
    24181 acagccactc tccagttcaa ttggagagtt tttttgatga gagtagatat ttatagacct
    24241 caatttgaca ccatacattt tctatgataa aatgtaacaa atttatttac aacaaatcga
    24301 aatctaaatg aaatggaatt ttctatgaaa tcaatcaaag gactactctt tatcatagct
    24361 agttttatct tgactctttt gacttggatg aacacttctc cccaattcat gattccagga
    24421 ctagctttaa caagcctatc tctgactttt atcctagcca ctcgtctccc actactagaa
    24481 agctggtttc acggtttgga gaaggtctac accgtccaca aattcacagc ctttctctcc
    24541 atcatcctac taatctttca taactttagt atgggcggtt tgtggggctc tcgcttagct
    24601 gctcagtttg gcaatcttgc catctatatc tttgccagca tcatccttgt cgcctattta
    24661 ggcaaataca tccaatacga agcttggcga tggattcacc gcctggttta cctagcctat
    24721 attttaggac tctttcacat ctacatgata atgggcaatc gtctccttac atttaatctt
    24781 ctaagttttc ttgttggtag ctatgccctt ttaggcttac tagctggttt ttatatcatt
    24841 tttctatatc aaaagatttc cttcccctat ctagggaaaa ttacccatct caaacgctta
    24901 aatcacgata ctagagaaat tcaaatccat cttagcagac ctttcaacta tcaatcagga
    24961 caatttgcct ttctaaagat tttccaagaa ggctttgaaa gtgctccgca tcccttttct
    25021 atctcaggag gtcatggtca aactctttac tttactgtta aaaattcagg cgaccatacc
    25081 aagaatatct atgataatct tcaagccggc agcaaagtaa ccctagacag agcttacgga
    25141 cacatgatca tagaagaagg acgagaaaat caggtttgga ttgctggagg tattgggatc
    25201 acccccttca tctcttacat ccgtgaacat cctattttag ataaacgggt tcacttctac
    25261 tatagcttcc gtggagaaga aaatgcagtc taccttgatt tactccgtga ctatgctcag
    25321 aaaaatccca attttgaact ccatctaatc gacagtacga aagacggcta tcttaatttt
    25381 gaacaaaaag aagtgcccga acatgcaacc gtctatatgt gtagtcctat ttctatgatg
    25441 aaggcacttg ccaaacagat taagaaacaa aatccaaaaa cagagcttat ttacgaagga
    25501 ttcaagttca aataagtaat catactctcc tgggaaatcc caggagagtt ttttatagcc
    25561 aaatgaaata agacaggaac gatggaattt tggcattcaa atcaattgat aagactattt
    25621 tatagtggag tgaaatagga tacgaacaaa ttgattagga aaatcaaatg aatttataga
    25681 aatcttttag cagttatgtt atcctattct agtttcaaaa cgctatagaa gcagcattgt
    25741 actagtctag attcagttta ctatactaaa acgagtagct tgaaatcaaa aaacccaccc
    25801 tcacaggcag gttttatctg tattattcag ctagattatg ctttaccttc tgaaccgaat
    25861 acgtcgatac gttcttcaac cgatgcttgg atagctttta caccgtcagc caagaattta
    25921 cgtgggtcga agagtttttt cttgtcgtat tctgcttcgt ttgcttcgta gtcacgagca
    25981 aatttacgag ttgcgttagc gaatgcgatt tggcattctg tgttaacgtt aactttggca
    26041 acaccaagtt tgatagctgc ttggatttgc tcatcaggaa tacctgatcc accgtgcaat
    26101 acgattggga atcctggaag agcttctgtc aatttttgca agtggtcaag gtcaagacct
    26161 tcccagttta ctgggtaagg accgtggatg ttaccgatac cagctgccaa gaagtcgata
    26221 ccagtttcaa ccattgcttt agcgtcttcg attggagcca attcaccttt accgatgatt
    26281 ccgtcttctt caccaccgat agtaccaact tcagcttcta ctgagatacc tttagcgtgt
    26341 gctttttcaa caacttcttt agccaattta aggttttctt caactggaag gtgtgaaccg
    26401 tcaaacatga ttgaagtata accaacttcg atacactcaa gtgcatcttc gtagtgaccg
    26461 tggtcaaggt ggatagctac tggtacagtg atacccattg attcaacaag gttagcgatc
    26521 aagttgcgag caactttgta accacccatg tatttagcag cacccattga agtttggatc
    26581 aaaactggag cttttttagc ttctgctgcg cgcaagatag cttgagtcca ctcaaggttg
    26641 tttgtgttaa atccaccaac tgcataaccg ttgtcacggg ctgcttggac aaatttttct
    26701 gctgaaacga ttgccatttt atcaggcctc ctgtatattt ttatgggtca tcccatttac
    26761 attgttcatt ttatcacttt ttgccaaaaa aatctagttt ttcccgcagt ttcgattgat
    26821 tttcttctaa ctccatctat gtaaaccctt tctctcccta gtcttgggcg acttttggaa
    26881 aagctataaa gaaggttaaa cgattctcct ccatctcgaa acgataagct aatttttcat
    26941 gttctaatag actcttaacc acaaagagcc ccataccaga ccccttgacc ttgcgactgg
    27001 cattgtcaga aaaagactgg gctagttttt cttgttcctc tgagctacag ctattttcga
    27061 taaaaagttc tccttctctt tctccaattc gaactaagcc acctggaaca gagtgcttaa
    27121 tggcattgct gatgagatta gaaagaatca acttcataac tgatgggttt agataagcct
    27181 gctgatgggt caaactattg tctatctgga gctctctttc cttggctagc aaggcataat
    27241 ctttgaccag attttgcgtc atctggagga ggtcaattgt ttccctatca tctcgcaatt
    27301 cctgcacaga agagagggaa agtatctgca gaacatggtg attgagttca tccacaatcc
    27361 ccaaggcaac tcccagatac tggtctctat ccttataacg accgatattc tctctcatat
    27421 tttcgattag gattttcaaa ctagccagcg gtgttttcaa ttcatgagaa gctcctcgta
    27481 ggaattcgac cttcatcttc tccagctgga gaatggcttc attcttttca tgcaagtccg
    27541 caataacagt caagagatgc tggtagaggc tattgatttg ttccttgaga ttacctatct
    27601 catccttaga atccacgcgc aatcgcactt gggaatccag gtccatcatc cgacgggtca
    27661 cccgcttgat ttccaaaatc ggtgcaacaa tagtccgggc gtagatgtag gccaccaaga
    27721 gggaaatcag aaaggaggcc agcaaggtat agggaagaaa ctggagactg atttgctccg
    27781 cttccttttg taaatccatg gaagctagaa actggagaat catagtacca ccgtcttgcg
    27841 ttttcacctc gcgctcctca ataaagagag aggttgtctg gcggtctgtg tccagaggaa
    27901 gactgtcctt gacttctaac ttgtcctcgg tcatctcacc tttgacggtc cccttgatat
    27961 cactagtctg ggaatacaag tctaacactt gctcgatact ctgcctatct ttcccttcta
    28021 gggactgggc aatggctgtt gccttttgac caatggtttc ctgacgatga ctcagataag
    28081 tcgaaggaaa aagaaaataa atagctaaat gaaggcagat aaccagaaca ctaaatatcg
    28141 agaaggtata gataaatatc tttgcaaata aacctgttcg tttcattttc gctccaattt
    28201 ataaccaaca ttgcgcacag tgaggataca atccaagtct agctttttcc gcaattcctt
    28261 gatataaaca tcaataacac ggtcaaaggg aacctcatct gtcgctttcc agacggcatc
    28321 gataatctga gaccgagtca aggcccggcc ttcatttttc actagatagt ccagaatttc
    28381 caactctttg gcattgatag gcacttcttg acctgcgagg cttgcactgt agctttcaaa
    28441 gtccaccttg gtatccttgt aagaaaagat tcgtcctgta tcgtagtagc gcttgaaaat
    28501 cgcgtccacc ctcactttta agagggagag agagaaaggt ttttccagat agccatctgc
    28561 caaagaggca aaggcactca tcttgtattc ctcatcctga aaagctgtca acatcaagac
    28621 aggaacctga ctggttttac gaatctcagc taggacttct aagccgttaa gcttgggcat
    28681 ctggatatcc agtaaaacca gggccacctc atagctagaa aattgctcca gagcttcctg
    28741 accgtccgct gcctcaatag tttcatagcc acaatccgtc aaataatcac tgaccccctc
    28801 acggatcatc tcttcatctt ctacaattaa aattttcata ctttaactgc tctctatttt
    28861 ttatttttct tagaataaat acctactcta ttttctatta tagtctcttg ctggcctttt
    28921 gtctgtaagc aactgatcac tagataaaac gttgtgaaat tcctttctca taaattccat
    28981 aactttagta tattatattt aagcactaaa gtacaaagaa agcaactgaa agcaatgatt
    29041 ttcaccactg ctttcagatt tattttgaat tgttaaatag ctattcctat ccactattct
    29101 tgaatagaaa cacaagatgc aatctttatt ccagactcat tttttcaaat ttattcacca
    29161 tccagcaaga gctcttttgg ttgttttcta aggagattgc ttgaagcaag cgccataacg
    29221 agaaccacta gaaccaaggc aaggacaaaa atgatgataa agtctgatgt ctgaatggaa
    29281 atgtctaggc tcgacaaggt cttgctaaag ccatctactt ctgcaccgcc accaaggtta
    29341 gaggcttgag ccgccttact agcctgtttg gcaacacctg aagtcacatt ggcaaggaca
    29401 gtgtttccaa ttgcacgggc agtgtaatta gctaggaagt aagcagaaac tagagcaggg
    29461 atagcaatca agatagattc ggtgatgaat tgacccaaga tacttgcctg cttgaggccg
    29521 atagagagga gaattcccac ttccttgcga cgggcgttga tccaaaggct gagcaagagg
    29581 gcaaggagga gaactgagaa gctcaagcta ccccagaaga ggaggttggc catcttgtac
    29641 ataccagaga tagattgctc aagagctggg tagttagagg agctcttgac gagtgtgtag
    29701 ctcttccagt tgataccact gatgccattc aactctttca taacatcatc caagttcttg
    29761 tctgctgtta caaagaaggt tgcgtcccca taaatggctg tgtcttctgt gtatccataa
    29821 agttttgcag cagtgtgaat gtctgtaata gctgtgtttt cgtaaagttc ttgtgagtag
    29881 gttactgctg acttattatg accatcaaag agtcccttga ttgtcacttc aactgtttcc
    29941 ttggctcctt tttcattatc tgcatcgtag atattagagt ccagtttaac cttgtcccct
    30001 actttccagc cgtgtttggc tgccaagtcc ttgtgcaaga ggattttatc cttgtcgtcg
    30061 ttggttaagt gctctccttc gactagttta taagaaccag agacaaactt atcttcttta
    30121 gaggagtcat tgacacctgt aatcatcaag ctacttccaa aacgcttggc acgatcagca
    30181 gtgagattct tcttggtttc tggcgtttca atcaggtcat atccagtcaa atctccgata
    30241 gcgttgatac gtttgacata agactcgatg gccttgtttt cggtgatttt tttgatgtct
    30301 tcacccttga tattcccagc accacgaggc gttccttggt tgacgcgacg attgatttgc
    30361 atggagaagc tattggtgat atttttaaag gtctcctgag aagccttggc agtagctccc
    30421 ttgattgaca agccgaccaa actcaagctc gccatgagga gaataatcag gaagatgaca
    30481 atcgatttga aaaacttcct tgtaacatag gcaaatgcgt tgtgtaacat agattccctt
    30541 tctagatttt gttttaatca ttctatcaaa ataagctcaa attatttact agtattgcgc
    30601 gtttcagtca gtttcttatc ctttaattca agtgtaatat ctgacgcttg tgccacttct
    30661 ttactgtgag ttacgacaat cacacattta cctgttttct gggcaagtga tttgagtagt
    30721 tcgacaatat ctccagcagt tttaggatcc agatttcctg ttggctcatc agctagaata
    30781 actggagctt ctgagaccaa actgcgagca atggcaacac gttgctgttg accacctgat
    30841 aactggagaa cattccgctt gatctggctt tcatccaaac caagctcaag aagtgtattc
    30901 ttgcttgcct ttttgttgac caatcggata ttttccagcg gagaaagata atctatcaag
    30961 ttataatttt gaaagaccag ggaaatatgg tgcatgcgat ggtaagaata gcccttctta
    31021 cgaatatcct ctccttgaaa aaggatagaa ccttcaacag gactatctag accagcaagt
    31081 agggacaaga gtgtggattt tcctgctcct gactccccaa taatactgta aaattttccg
    31141 ggttcaaaat tataatcgat ctgatatagg actgcttcag cagtattctt ataacggtag
    31201 gtaacatctt gtaattgtaa taaagtcatg atttctcctt cttaactaat agatgataaa
    31261 atttctttcg gtgattttct aaataagaat aggaaacaaa gggctacaga taagcaacta
    31321 agcagaacta gaaaaacata ggattctgca aaagataaga tactagttga taaactgctt
    31381 gctttggcta gtgtatcttg taagcttgcc tgatctccac ttgctagtag agtttggagt
    31441 aggtaagttg tgattccgtt tcctgcaaca aatgctggaa gcaaagctcc aagagatacc
    31501 aaaactacct ctaaacagaa ttgtaggaag atcgagctct tgccttttcc aagtgcaagt
    31561 aaaatcccca cttcatagac ccgttctctc aaccagagag acaaaaccag aattaaggct
    31621 ccagctcctg ctatcaacat cccataaagg aagatggtca ggaaggtttg gaaagttgca
    31681 actgagtctt tgatttgttc aaaagccttg ttttcctttt cgacttggta gccttgattt
    31741 tccaaggcca agttttctac ctgcttcatg agtccgtcca tttccttagg attttctaca
    31801 tagaagcgtg ctgcactgac ttgagcttca ctattgccca aaagggtttg gctactttca
    31861 tagtctgtaa agacttgatt ttcactgaag tcagaagaca agcctgtgaa tttctcttgt
    31921 tttttaccag aaaagatgcc gataatctca aactctactg tttgtccttt tccagattca
    31981 gactgaccag catccaagcc aatcttgtca tgaagtgaaa gaccgttctt cttagccaat
    32041 tcttcgtgga taaggatttt cttggaatcc cctttttgaa ggtgtcgccc ttcttttaga
    32101 ttgaaagccg aactggtaaa ggttacatcc ttggatgaat cctcaagagc cgttaagcta
    32161 accaagttat tgtctgcagc tgataaatca tcacgctcca cgctctgctc gccagtcact
    32221 gcttccttgt cttttagttt tgcgaccgtc tcaagttcag gagagacatt ttccagcccc
    32281 ttaatcttgc ttacagatgc taggtctgac aacttgaatg tctgaccatt ctctatcttc
    32341 ttaatagaaa aagatgtatt gagtgattta taaagattgc tttctactgt tttgttggac
    32401 ttcatcagag tcaaacaggc tgaaattccg gccaataaga ccaataaaat cagaaataaa
    32461 ataaaacttc tcagtcgctt tctgctgaca taagcccaag atctttggat tggattcatt
    32521 tgtcacctcc atatttgtaa gactattata aaacccaaat atgaaatgtt tatgaaatac
    32581 gaaaaaaaaa tatcgagtag gggataatct ctagcccctc tcacaccacc gtacgtgccg
    32641 ttcggcatac ggc
//
LOCUS       DAVLCS010000025        32087 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLCS010000025 DAVLCS010000000
VERSION     DAVLCS010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32087
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.025"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            5..778
                     /locus_tag="VXC78_001279"
     CDS             5..778
                     /locus_tag="VXC78_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEV0583362.1"
                     /translation="MYYLALIDYPNIQEWELEKIAKFIAYEKLHKRQTSIECADSCLK
                     KEILDYICQHPFLPPFTPTDKRVASTYDLHKRLVTSDYCSHTTTIDAAISIFKTGQLL
                     SAVKAFRRDAEELVLDSRNAASDPIDYFDYVMLGWSNTSSGYRLAMERLLGRAPSEKE
                     LQDKFIPGVSFHFIYTDLIKVTGYIFDGYHVAKIKDMLNLFSELYICIIPTHNKSQFE
                     NIIPTKIQDRVHYLDYAGEDLEEWTKKVYQVVLKQSDKG"
     gene            792..1664
                     /locus_tag="VXC78_001280"
     CDS             792..1664
                     /locus_tag="VXC78_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV0583363.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            1946..2629
                     /gene="rpiA"
                     /locus_tag="VXC78_001281"
     CDS             1946..2629
                     /gene="rpiA"
                     /locus_tag="VXC78_001281"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV0583364.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            2643..3854
                     /locus_tag="VXC78_001282"
     CDS             2643..3854
                     /locus_tag="VXC78_001282"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV0583365.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            3856..4398
                     /locus_tag="VXC78_001283"
     CDS             3856..4398
                     /locus_tag="VXC78_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV0583366.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            4414..5223
                     /locus_tag="VXC78_001284"
     CDS             4414..5223
                     /locus_tag="VXC78_001284"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0583367.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRTYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            5699..6679
                     /locus_tag="VXC78_001285"
     CDS             5699..6679
                     /locus_tag="VXC78_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV0583368.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGCYLAQIAEVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWNAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTP
                     LIHNDRDIVTFTGNSRFKHRSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRF
                     FKKQALPRSSSQPSAEPMENIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHT
                     NFQSKPWWQVDLAKEETIRQINIYNRTDTAQDRLANFDVILLDSSGKELE"
     gene            6704..7216
                     /locus_tag="VXC78_001286"
     CDS             6704..7216
                     /locus_tag="VXC78_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV0583369.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            7874..8584
                     /gene="deoD"
                     /locus_tag="VXC78_001287"
     CDS             7874..8584
                     /gene="deoD"
                     /locus_tag="VXC78_001287"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0583370.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVEYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(8607..9131)
                     /locus_tag="VXC78_001288"
     CDS             complement(8607..9131)
                     /locus_tag="VXC78_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV0583371.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRK
                     LDQFLDKKRKSYNS"
     gene            complement(9184..9420)
                     /locus_tag="VXC78_001289"
     CDS             complement(9184..9420)
                     /locus_tag="VXC78_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV0583372.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(9488..10408)
                     /locus_tag="VXC78_001290"
     CDS             complement(9488..10408)
                     /locus_tag="VXC78_001290"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV0583373.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEIYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            10598..11003
                     /locus_tag="VXC78_001291"
                     /pseudo
     CDS             10598..11003
                     /locus_tag="VXC78_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            11219..11800
                     /locus_tag="VXC78_001292"
     CDS             11219..11800
                     /locus_tag="VXC78_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0583374.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            11797..13074
                     /locus_tag="VXC78_001293"
     CDS             11797..13074
                     /locus_tag="VXC78_001293"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV0583375.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYCPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            13092..13754
                     /gene="deoC"
                     /locus_tag="VXC78_001294"
     CDS             13092..13754
                     /gene="deoC"
                     /locus_tag="VXC78_001294"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV0583376.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGSDFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            13741..14130
                     /locus_tag="VXC78_001295"
     CDS             13741..14130
                     /locus_tag="VXC78_001295"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0583377.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            14220..15272
                     /locus_tag="VXC78_001296"
     CDS             14220..15272
                     /locus_tag="VXC78_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV0583378.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            15416..16951
                     /locus_tag="VXC78_001297"
     CDS             15416..16951
                     /locus_tag="VXC78_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583379.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVVDISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            16944..18002
                     /locus_tag="VXC78_001298"
     CDS             16944..18002
                     /locus_tag="VXC78_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0583380.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            18005..18961
                     /locus_tag="VXC78_001299"
     CDS             18005..18961
                     /locus_tag="VXC78_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0583381.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            19046..20162
                     /locus_tag="VXC78_001300"
                     /pseudo
     CDS             19046..20162
                     /locus_tag="VXC78_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(20205..20846)
                     /gene="plsY"
                     /locus_tag="VXC78_001301"
     CDS             complement(20205..20846)
                     /gene="plsY"
                     /locus_tag="VXC78_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV0583382.1"
                     /translation="MITIILLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            20982..22925
                     /gene="parE"
                     /locus_tag="VXC78_001302"
     CDS             20982..22925
                     /gene="parE"
                     /locus_tag="VXC78_001302"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV0583383.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KVGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRSDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            23345..25816
                     /gene="parC"
                     /locus_tag="VXC78_001303"
     CDS             23345..25816
                     /gene="parC"
                     /locus_tag="VXC78_001303"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV0583384.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            25948..26970
                     /locus_tag="VXC78_001304"
     CDS             25948..26970
                     /locus_tag="VXC78_001304"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV0583385.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            27026..27730
                     /locus_tag="VXC78_001305"
     CDS             27026..27730
                     /locus_tag="VXC78_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0583386.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            27795..28484
                     /locus_tag="VXC78_001306"
     CDS             27795..28484
                     /locus_tag="VXC78_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV0583387.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            28481..29404
                     /locus_tag="VXC78_001307"
     CDS             28481..29404
                     /locus_tag="VXC78_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV0583388.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            29419..30063
                     /gene="pcp"
                     /locus_tag="VXC78_001308"
     CDS             29419..30063
                     /gene="pcp"
                     /locus_tag="VXC78_001308"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0583389.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            30231..30461
                     /locus_tag="VXC78_001309"
     CDS             30231..30461
                     /locus_tag="VXC78_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV0583390.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            30511..30591
                     /locus_tag="VXC78_001310"
     tRNA            30511..30591
                     /locus_tag="VXC78_001310"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30545..30547,aa:Tyr,seq:gta)
     gene            30601..30672
                     /locus_tag="VXC78_001311"
     tRNA            30601..30672
                     /locus_tag="VXC78_001311"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30633..30635,aa:Gln,seq:ttg)
     gene            30834..32036
                     /gene="rpsA"
                     /locus_tag="VXC78_001312"
     CDS             30834..32036
                     /gene="rpsA"
                     /locus_tag="VXC78_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV0583391.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQKFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT         9723 a         5648 c         7295 g         9421 t
ORIGIN      
        1 tggaatatac tacctagcac taattgatta tccaaatatt caagagtggg aattagaaaa
       61 aattgctaaa tttatagctt acgaaaaact tcataaacgt caaacaagta ttgagtgtgc
      121 tgattcttgt ttaaaaaaag aaattttaga ttacatctgt cagcatccct ttctgccacc
      181 atttacccct acagataaaa gagtagcctc gacttatgat ctacataaga ggttagtgac
      241 ttcagactac tgtagtcata ctacgactat agatgcagcg atttctatct ttaaaacagg
      301 tcagctctta tctgctgtga aagcctttag gcgagatgct gaagagttgg ttttggatag
      361 tagaaatgct gcatcggatc cgatagatta ttttgattat gtcatgttag ggtggtcaaa
      421 tacaagttct ggttatcgat tagcgatgga gcgtttatta ggtcgagctc cttcagagaa
      481 agaattacaa gacaagttta ttcctggagt gagttttcat tttatctata cagatttgat
      541 taaagttact ggttatattt ttgatggcta ccatgttgca aaaattaagg acatgttgaa
      601 tttatttagt gagttgtata tttgtattat tccaactcat aataagagcc aatttgaaaa
      661 tattattcca actaaaatac aagatagggt gcattatctt gactatgctg gagaagactt
      721 agaagagtgg actaagaaag tctatcaagt tgttttaaaa caatcagata aaggatagtt
      781 gaggaagaac gatgaaagtg attaatcaaa ccttattaga aaaagttatt attgaacgtt
      841 ctcgttcaag tcataaagga gattatggtc gtctgctgct gcttggtggt acttatcctt
      901 atggaggtgc catcatcatg gctgctttag cagctgtaaa aagcggtgca ggattggtga
      961 ccgttggaac ggacagggaa aatatcccgg ctctgcacag ccatttacct gagcctatgg
     1021 ccttttctct tcaagaccag caattgttaa aagagcaatt ggagaaggca gaagttgtct
     1081 tgctggggcc tggtttacga gacgatgctt ctggagaaaa tctagtaaaa caggtctttg
     1141 ttaatttaag ccaaaatcag attttgattg tagacggagg tgccttgacc attcttgcta
     1201 ggacaagttt gtcatttccc tcaagccagc ttatcctaac tcctcaccaa aaagaatggg
     1261 aaaaattatc tggaattacg attgaaaagc aaaaggaaga tgcaacggct agtgttctga
     1321 cttccttccc tcaaggaaca attttggtgg agaaaggccc agctactcgt atttgggaag
     1381 ttggccaatc tgattattac cagttacagg ttggtggtcc ttatcaggcg actgggggaa
     1441 tgggagatac tctggctggg atgatcgcag gatttgtagg ccaattccga caggccagtc
     1501 tctacgagcg tgtggcagta gcgacccatc ttcattcagc catagcccaa gaactatctc
     1561 aagaaaatta tgtggtctta ccgacggaaa tcagcaggta tcttcccaaa ataatgaaaa
     1621 ttatttgtca acaagagagg gtaagcaaag ataaacttgt ttaaaataga cagataaatc
     1681 tacttccttc tcttaattta tgattcttga aatgcgcctg ctttaaggct aaactagacg
     1741 tatcaaagtt aagagtttgt ttttgtaact ggaaagagat gaacaaatca aatacataaa
     1801 agataaactc atttttattc gtttggtaaa aataaaatgc atatttttaa agaaagattg
     1861 atgaaaaatg tagatttgat gtttttactt gaataaaaag cggtttcata gtaaaataag
     1921 aactgagaat gatggaggta aatcggtgga aaatctgaag aaaatggcag gtatcaaggc
     1981 tgctgagttc gtgagcgatg gaatggtcgt tggacttgga acaggctcga ctgcctatta
     2041 ttttgtcgaa gaaatcggtc gtcgtatcaa ggaagaagga ttgcagatta cagctgtaac
     2101 aacttctagt gtgaccacta aacaggcaga aggccttaat atcccgctca agtctattga
     2161 ccaagtagat tttgtcgatg tgacggttga tggcgcggat gaagtggata gtcagtttaa
     2221 tggaatcaaa ggcggtggtg gtgcccttct catggaaaag gtggtcgcaa caccatcaaa
     2281 agaatacatt tgggtggtgg atgaaagcaa gctggtcgaa aaactaggtg cttttaaatt
     2341 gccagtagaa gtggttcagt atggtgcaga gcaggtcttt cgtcattttg aacgagctgg
     2401 ctacaaacca agtttccgtg aaaaagacgg ccaacgtttt gtgacggata tgcagaattt
     2461 tatcattgac ctcgccttgg atgtcattga aaatccaatt gcttttggac aagaattgga
     2521 ccatgtcgtt ggtgttgtgg agcatggttt attcaaccaa atggtggata aggtaatcgt
     2581 tgctggacga gatggagttc agatttcaac ttcaaaaaaa ggaaaataga agggggcata
     2641 agatgtctaa atttaatcgt attcatttgg tggtactgga ttctgtagga atcggtgcag
     2701 caccagatgc taataacttt gtcaatgcag gggttccaga tggagcttct gacacactgg
     2761 gacacatttc aaaaacagtt ggtttgaatg tcccaaacat ggctaaaata ggtcttggaa
     2821 atattcctcg tgaaactcct cttaagactg tagcagctga aagcaatcca actggatatg
     2881 caacaaaatt agaggaagta tctcttggta aggatactat gactggacac tgggaaatca
     2941 tgggactcaa cattactgag cctttcgata ctttctggaa cggattccca gaagaaatcc
     3001 tgacaaaaat cgaagaattc tcaggacgca aggttattcg tgaagccaac aaaccttatt
     3061 caggaacggc tgttatcgat gattttggac cacgtcagat ggaaactgga gagttgatta
     3121 tctatacttc agctgaccct gttttgcaga ttgctgccca cgaagacatt attcctttgg
     3181 atgaattgta ccgtatctgt gaatacgctc gttcgattac ccttgagcgt cctgcccttc
     3241 ttggtcgcat cattgctcgc ccttatgtag gtgaaccagg taacttcact cgtacggcaa
     3301 accgtcgtga cttggctgta tctccatttt ccccaactgt tttggataaa ttgaatgagg
     3361 ctggtatcga tacttatgct gtgggtaaaa tcaacgatat ctttaacggt gctggtatca
     3421 accatgacat gggtcacaac aagtcaaata gtcatggaat tgatacacta ttgaagacta
     3481 tgggacttgc tgagtttgaa aaaggattct cattcacaaa cctagttgac tttgatgccc
     3541 tttacggcca tcgtcgtaat gctcacggtt accgtgattg cttgcatgag tttgatgaac
     3601 gcttacctga aattatcgca gctatgagag agaatgacct tctcttgatt actgcggacc
     3661 atggaaatga cccaacgtat gcaggaacgg atcacactcg ggaatatatt ccattgttgg
     3721 cctatagccc tgcctttaaa ggaaatggtc tcattccagt aggacatttt gcagatattt
     3781 cagcgactgt tgccgataac tttggtgtgg aaactgctat gattggggaa agtttcttag
     3841 ataaattggt ataagatgac gcgctatgct ttgctggtga gaggtatcaa tgttggtggt
     3901 aagaataagg tcgtcatggc ggagcttcgt caagaattga caaacttggg actggaaaag
     3961 gttgagagct acatcaatag tggcaatatt ttctttactt cgatagattc caaagcccaa
     4021 ttggttgaaa agctagagac tttctttgca gtccattatc catttattca gagcttttct
     4081 ttactgagtc tagaggactt tgaggcggaa cttgaaaatc taccagcttg gtggagcaga
     4141 gacttggcac gaaaagattt tctcttttac actgagggtt tggatgtgga ccaagtcatc
     4201 gcgacagttg aaagtttaga gctgaaagat gaagtgcttt attttggaaa acttgggatt
     4261 ttctggggga aattttctga agaatcctat tctaagactg cctatcataa gtacttgctg
     4321 aaggtgcctt tctaccgcca cattactatt cgtaatgcta aaacctttga caaaattggt
     4381 caaatgctaa aaaaataata aaggagacac acaatgacat ttttaaacaa aatccatgaa
     4441 actgctactt tcctgaaaga aaagggaatt gcagcccctg agttcggtct aatccttgga
     4501 tcaggacttg gagaattggc agaagaaatc gaaaatccag ttgtagtaga ctatgctgag
     4561 attccaaact ggggccgttc aacagtagtc ggtcatgctg gtaaattggt atatggtgaa
     4621 ctggcaggtc gcaaggtctt ggctcttcaa ggtcgtttcc atttctatga agggaatcct
     4681 ctggaagtgg tgactttccc agttcgtgtg atgaaagttc ttggatgtga aggtgttatt
     4741 gtaaccaatg cagctggcgg tatcggattt ggtcctggta ccttgatggc tatctcagac
     4801 catatcaaca tgacggggca aaatccattg atgggtgaaa acttggatga ctttggccca
     4861 cgtttcccag atatgtctag gacctacaca ccagaatacc gtgccactgc ccatgaagtg
     4921 gctaaaaaac ttaatatcaa gcttgatgaa ggtgtctata tcggagttac tggtccgact
     4981 tatgaaacac cagcagaaat tcgttcctat aagacactgg gagcagatgc agttggtatg
     5041 tctacggttc ctgaagttat cgtggcagcc cactctggct tgaaagttct gggaatttca
     5101 tgtatcacta actttgcggc tggtttccaa gaagaactca atcacgaaga agttgtagaa
     5161 gtgactgaac gtgttaaagg tgatttcaaa ggcttgctta aagcgattct tgctgaattg
     5221 taagaaaaaa gatttaaaag ggggagtgcc tctgtctttt caggattgac tgcctatccg
     5281 gattaaagaa gaaacagagg aatactatga gcttcttcct gctcttataa ctgaaagaag
     5341 cggaagaata ggtatgtctg atctgatagc cagcattgtg aaagacaaga ttctaggata
     5401 ctagcattag cttcctagcc aagtagacta gtatgataag gagagatgag aatgaattga
     5461 ctttctgaat ttctcagtct tatcatatat agcacaatga gatttcgctt gagtctgctt
     5521 gtaaataaac gaaaagaaag ataagaaata atgaaaattg gtcaacgaat tatgcgcttt
     5581 ggcataaaaa attaagtatc ggagttgtat ctgttgtagt cggctttgat ttctagctcc
     5641 agctggaatt tcagccaatg aagtaaagca agatgtaaca tctgaagtgg taataggtgt
     5701 gctagattct aaggaggaat tgaaagagtc agaaaatgat gctccaaaac tagaaactcc
     5761 tcttagagag gagccaagac tagctcctca aacgcttccg gaagcaagtg aagttcttga
     5821 aaacaaaagg gaagagtcaa aagtagagat aacagagcca gctcaagcgg atgatatccg
     5881 caaggttgtt ggggaattag ccaaggatat aagtattact aagttgtata tgacaggtca
     5941 ttctcttgga tgctacctag ctcagattgc agaggttgaa gcttaccaaa aatatcctga
     6001 tttttataac catgtattga ggaaagtgac aactttcagt gctcctaaag tgattacttc
     6061 cagaactgtt tggaatgcta agaatggttt ctgggatgtt ggtttggaaa gtcgtaaatt
     6121 agctgttagt ggaaaaatta agcattatgt ggttgataat gacaatgttg tgactccctt
     6181 gattcataat gatcgtgata ttgttacatt tacaggtaat tcacgcttta aacaccgttc
     6241 tcgtggctat tttgaaagtc caatgaatga tattcctaac tttaatattg gtaaacaagc
     6301 taccttggat aaacatggtt atcgtgatcc gaaattggat aaagtgcgat tctttaagaa
     6361 acaggctctg cctcgatctt ctagtcaacc aagcgctgaa ccaatggaaa atattgcctt
     6421 aggaaaacag gttactcaaa gttcgacagc tttcggagga gatgctagaa gagctgtgga
     6481 tggcaaagtc gatggtaact atggtcacaa ttctgtcact catacaaact tccaatctaa
     6541 gccttggtgg caagtagatt tggctaaaga agaaaccatt cgccaaatca atatttacaa
     6601 ccgaacagac actgcccagg atagattggc aaactttgat gtcattcttt tagacagttc
     6661 tggtaaagaa cttgagtgaa aacgtataac atctcctaaa gatgtgtcag cacaaattac
     6721 gattaaccat aaaaaagcgc gctatgttcg gattgagcta gaaggctata atgccctcag
     6781 tcttgcagaa gttgaagttt tccgctttat agctacgaat ggtgaaacgg cgatacaagt
     6841 ttctaagtca gttcaaccaa tcagtcagac tcctgtgaag gataaaacat tgacaattca
     6901 acacagtgga gcttacattg cccgctactc cataacttgg gaagaagttc cagtagataa
     6961 agatggaaac caagttgttc gtagtcattc ttgggaagga aacggtcgca accagactgc
     7021 aggttttgtc ctcaacctcc caatcaaaga aaatatgaga aatctgcgag ttaagattga
     7081 gaaaaagacg ggcctactat ggaatagatg gcaaacaatc tatgaaaaca gaccaatttt
     7141 agctcaaccc caccgtaaaa ttacccattg gggtacgaca ttgaattcca aggtgagtga
     7201 cgatgatgtc ttgtaatctg atggtacaat gatagttagt ttgtctagtt tataagaaag
     7261 tactacctga gcttgaatag gactcaggta gctctctgtg aaagaacaaa attaatactc
     7321 aatgaaaatc aaagagcaaa ctaggaaact agccgcaggt tgctcaaagc actgctttga
     7381 ggttgtagat aagactgacg aagtcagtca catatataat ccaaggcgac gttgacgtgg
     7441 tttgaagaga ttttcgaaga gtataaacag aaaggtagag cgcgtgttct aatttgaaca
     7501 cgagtagaaa acttttctaa aaacaaaaac gaaaggatgg gtaaactgta ttcgctgaac
     7561 tgaatacggg cgactctcct ctaaatcaaa attaagaaag aaaggaattg accccaccct
     7621 aaaagcagtg ggaaaaagat agttggtcta gcgagcatcg ctcactgcgc ccaactccta
     7681 ttttcccttc gctttttgat gggtttggta tctttctcaa tataaaatat aaaataaaga
     7741 aaggtagagc gtgtgttttg atttgaacac gagcggaaaa ctcggaaaat agataatctg
     7801 actgaaaaat caggatttct cgtcaggttc ctaattttca gtcgttttct tctcgctctt
     7861 tgtatcataa attatgtcta tccatattgc tgctcagcag ggtgaaattg ctgataaaat
     7921 tcttcttcct ggggatcctc ttcgtgctaa gtttattgcg gagaatttcc ttggtgatgc
     7981 tgtttgtttt aacgaagtgc gtaacatgtt tggttacact ggtacttaca agggtcaccg
     8041 tgtatctgtc atgggaactg ggatgggaat gccatctatt tcgatttatg cgcgtgagtt
     8101 aatcgtagaa tacggtgtga agaaattgat tcgtgtggga actgcaggtt ctttgaatga
     8161 agaggttcat gttcgtgaat tagttttggc gcaggcggct gcaaccaact caaacatcgt
     8221 tcgtaatgac tggccacagt acgattttcc acaaattgct agctttgatt tgcttgataa
     8281 agcctaccat atcgccaaag aacttggtat gactactcac gttgggaacg ttttgtcatc
     8341 tgatgtcttt tactcaaatt actttgaaaa gaatatcgag cttggtaaat ggggagtcaa
     8401 ggctgtggaa atggaagcag cagctcttta ctatcttgct gcccaatacc atgttgatgc
     8461 gctagctatc atgaccatct ctgatagctt ggtcaatcca gacgaagaca caactgcaga
     8521 agaacgtcaa aataccttca ctgatatgat gaaggttggt ttggaaacct tgattgcaga
     8581 ataattatag ccaaaaagga agccctttat gaattgtagg acttcctttt cttatccaga
     8641 aattgatcta gctttctctg atttcgaaga atagtgactt tatgtgaata ttcttggcaa
     8701 agtttttggt aattttcttt ttgagttttg ctacgcccat cccaaagaat ccatctgata
     8761 aactcccact caaagcgttc agggcaatct gccgccatac tttctctgac ttttccacgg
     8821 tatttaagat aacgcttaaa ggctctaaag agacaggtta atggcgaaaa attgagaaag
     8881 atgatttggt cagcttcttg cattcgttct tggtagtagc accaagaata attaccatcg
     8941 atgacccaag ctttatgctt ggtgagaaag ttttttatct cggttaacat ccattcgcag
     9001 tcactgtctt gccaaccagg ttgaaattgg agtgtgtcca tgtgcagttt tggaatggag
     9061 tagtagttag ataacttttc tgctagagtt gacttaccag aaccagaata tccgataatt
     9121 gcgattttca ttttctacct tttcctattt ggagacaaaa aaacagcctc tatggactgt
     9181 ttcttattta gcaagtttag ctgaaagacg agctttatcg cggcttgctt tgtttttgtg
     9241 aatcaaacct ttagtttctg ctttatcgat agctgagcta gcagcacgga aaagttcttc
     9301 agatgggttt gcttcgaaag cttttatagc agtacgcata gctgattttt gagctgagtt
     9361 cttttcgttt tgtttaacgt tcaattcagc gcgtttgata gctgatttaa tgtttgccaa
     9421 tgttcttacc tccatattta ctaactatac cattatatat gaaaacttac gttttgacaa
     9481 gggaaaatta cttttttaag taaatttcat cgatttcatg gttcttgctt ttatgaagaa
     9541 tcacttctgc acgatttctg gttggttcaa tataattttg cagatttgtg agattgatac
     9601 tgatccagac ctgatgggca aaggactcta cttccccaat cggcatctga gtaaaacgat
     9661 aatagtagct atcagggtcg ttttgggcta ggctcagcat tttcaagaaa cggtccagat
     9721 accaactttc aatatcatcc actccagcat ctacatagat ggaaaagtca aagaagtcag
     9781 tgatatagag acgatcgttt tgtggatttt gaaagacatt gattccctca acaattacaa
     9841 aatcagcagc tttgacactt tgtttctctt cgggtacgat gtcgtaaatt tcatgagaat
     9901 agacaggaat atctacatct tgtccatttt tgatgcggtc caagaagttg agaagagctt
     9961 ccatatcata gctttcagga aatcctttac gatttaaaat cccctgctca atcaaggttt
    10021 gattgggata gagaaaacca tcagttgtaa ccaactcaac cgtagcatct gtaaacgtac
    10081 gggacagtag gatttgaagt aggcgactgg ttgtggattt tccaacggca acactcccag
    10141 aaaccccaat aataaaaggt tgagatttac tttcacgttg gaggaaaatt ccttttgaaa
    10201 aggctaaatc ttccttagtt cgcttgtaaa tctgaatcag atgagccaag gggagataga
    10261 tatctgtaac gtcttggaga ctgatttggt cattaaaact cttgatagat tccaattctt
    10321 cttctgttaa aggaggtgtt gtttttcgat gtaaagattg ccaagtctgg cggctgattt
    10381 tttcaaaatg taaaaattcg ttggtcattt gttttcccct agatattttg tctatcatac
    10441 cataaaaagc taaaaaaata aagcggtttc ttgaatgtgg taagtcaatg gtatataata
    10501 taagtgatca atttattgat gaaataggag gtagattcta ctgatttata agcttataaa
    10561 gggggctttt tagttcacaa cttataggat gtgtactatg aaaatcttaa aatgttacat
    10621 attggaactc tgttttattt taagttttgc tttacctttt ataaaaggag ccaatgcaga
    10681 taatggtaga tgctttgtgg aaacctatta tggttttact tttttgatgg aacatgctat
    10741 tgtaacagct gtctttatct gttcgctctt aattgctttc ttactaaaaa aaacgatggg
    10801 cgaaatggat tgctgctggt agttattgct ttttagtcct atggattgcg acagagggtt
    10861 atttcttcca catgtcacta gaagatttga tacgactttg gacaagtttg gaaatcctga
    10921 cacaaacgta tcagttgggc ttttatctaa atattttgtt aggaattttg ttgatgatta
    10981 agcatttgaa ggttaagcaa tagtaatcaa aatgcgcctg atgatagaca ataaactttt
    11041 tgtttttatc tggactgtga tatttatagt tctaaatggt ttattattta taagtgttga
    11101 aagagattga agaaaatggc ttcgtgactc gctttcttcg gtctttttcg ttttattatc
    11161 aatttgtaaa cgatttacaa tttgagtcaa attatggtaa aatagtgtca tgagtaaaat
    11221 gtattatgca gaaaatcctg acgctgctca cgacattcat gagttgagag tagagttgtt
    11281 gggacaaaaa atgacctttt tgacggatgc gggtgttttt agcaagaaaa tagttgactt
    11341 tggaagtcaa ctcttgctca agtgtctgga tgtcaaccaa ggagagacag tcctagatgt
    11401 aggctgtggt tatggtccat taggtttgtc cttggtcaag gtttacggag ttcaggcgac
    11461 catggttgat attaacactc gtgccctgga tttagctcgg agaaatgctg aaaaaaataa
    11521 tgcaaaagcg acgatatttc aatctaatat ttatgcaaga gttcaagggc gatttgacca
    11581 tgtcatttcc aatcctccta tccgtgcggg caagcaagtc gttcatgaaa tcatcgagaa
    11641 aagtaaagat ttcttggaaa ctggtgggga tttgacaatc gtcatccaga aaaaacaagg
    11701 ggctccaagt gctaagtcca agatggagga tgtgtttggt aattgtgaaa tccttaaaaa
    11761 agacaaagga tactatatcc ttagaagtgt gaaagaatga gagcagttga tttaatccaa
    11821 aaaaaacgag acggtcaaga actgacttca agtgaaattg aatggctgat agaaggctat
    11881 gtgtcaggaa ctgttcctga ttatcagatg tctgcctttg ctatggctgt ttattttaaa
    11941 ggaatgacga ctcgtgaaat ttctgattta acgatgaata tggttaagac tgggcaagag
    12001 tttgacctgt cagccattga tggtgtgaaa gttgacaagc attctactgg tggtgtcggc
    12061 gataaggtaa ccttgatttt agctcctctt gttgctagct tcggtgtgcc tgtagcaaaa
    12121 atgagtggtc gtggtcttgg ccatacaggc ggaacaattg ataaattgga gtccattaag
    12181 ggctatcaag tagaacgtag tcaagaggat tttattcgtc aggttcagga tattggagta
    12241 tctgtcattg ggcaatcaga ccagctggtc aaagcagata agcttctcta tgcccttcgt
    12301 gatgtgaccg caactgtcga cacgattcct ttgattgcga gttcggtgat gagcaagaaa
    12361 attgcggcag gggcggatgc tattttgcta gacgtgactg tcggtgaggg tgccttcatg
    12421 aagacggttg atgaggcgcg tgagttggct caaactatgg tagatcttgg taaggttgtt
    12481 ggacggaaga cagtagcagt gattacggat atgagccagc ctttgggacg agcgattgga
    12541 aatcgtctgg aaatccttga agcattggag attttgcaag gtcaaggacg tcaggatatt
    12601 acccacttta tttgtgaatt ggctcaaatt atgcttggtt tggcaaatgt taacaaaact
    12661 gttgaagaag ttcgccaaca tcttgagaat ggtcaagcac tggctaagtt tgaggaaatg
    12721 gtgcaagccc aaggtggaga cttggaagac ctctattgtc ctgtaaatgt agctcatgtg
    12781 gtggaaatcc ctgctcagga aacgggtgtc atttcagctc ttccagctat ggactttggt
    12841 ctttatgcca tgaggctggg tgctggtcgt gcagttaagt ctgatgcctt ggactatgaa
    12901 acaggaattg tttttgaaaa gaagattgga gactccgttc aaaagggtga aattgttgca
    12961 aaagtataca caaatgaaaa aattccacct caactagtta cagatttcca aaaatgtgtt
    13021 aaaataagtg atgaagtgaa aaaaatccgt gaaattgtag aaatcatctc ctaaatggag
    13081 ggaaaaccga aatgaaatta aataaatata tagatcatac gcttttaaaa caagatgcaa
    13141 agaaaaaaca aattgatagt ttgttgtctg aggctagaga gtatgacttt gccagtgttt
    13201 gcgttaatcc gacctgggtt gaacatgcta aaaaaggact tgaaggcaca gatgttaagg
    13261 tttgcacagt agtaggtttc cccttgggag caacaacttc aactgtgaaa gcttttgaaa
    13321 caaaagaagc tatccaaaat ggggctgatg agattgacat ggtaatcaat gttggggctc
    13381 tcaagtcagg tgatttggcc ttggttgagt cggatattcg tgcagtagtg gaagcaagtg
    13441 gggacaagtt agtgaaagtc attattgaag cttgccttct gacagaccaa gaaaaagttt
    13501 tggcttgcca attagcccaa aaagcaggat ctgactttgt caaaacatct actggctttt
    13561 caactggtgg tgctacgata gcagatgtta gattaatgcg tgaaacagtt ggatctgata
    13621 tgggagtcaa ggctgctggt ggagctcgtt cttatgcaga tgctcttgcc tttgtcgaag
    13681 caggtgcgac ccgtatcgga acgtcagctg gggtagctat tttaaaagga gaattggcag
    13741 atggcgacta ctgagttgat tgaactggca attgaaacca gcaaacatgc ctatgtcccc
    13801 tattctcact ttcctatcgg agcagtttta gtagccaaag acggaagtgt ttacacggga
    13861 gtgaatatcg aaaatgctag ctatcctttg accaattgcg gtgagagaac agctattttt
    13921 aaggctatat ctgaaggcca aagagaattt tcagaattga ttgtctatgg tcaaactgaa
    13981 aaaccgatct cgccatgtgg tgcttgtcgc caagtgatgg ctgaattttt tgaacaagat
    14041 ctaaaagtga ccttagtcgc aaaagataaa tcgacggtcg agatgacggt cggggaatta
    14101 cttccatact cttttacaga cttaaactag tctgagtcgc tctctgagtg gcacggtcct
    14161 tgtggccaac caatccatac ttgcaacatc gttgcacatc ttatttagga ggttcagtaa
    14221 tgaacaagaa acaatggcta ggtcttggcc tagttgcagt ggcagcagtt ggacttgctg
    14281 catgtggtaa ccgctcttct cgtaacgcag cttcatcttc tgatgtgaag acaaaagcag
    14341 caatcgtcac tgatactggt ggtgttgatg acaaatcatt caaccaatca gcttgggaag
    14401 gtttgcaggc ttggggtaaa gaacacaatc tttcaaaaga taacggtttc acttacttcc
    14461 aatcaacaag tgaagctgac tacgctaaca acttgcaaca agcggctgga agttacaacc
    14521 taatcttcgg tgttggtttt gcccttcaca atgcagttga agaagcagct aaagaacaca
    14581 ctgacttgaa ctatgtcttg attgatgatg tgattaaaga ccaaaagaat gttgcgagcg
    14641 taactttcgc tgataatgag tcaggttacc ttgcaggtgt ggctgcagca aaaacaacta
    14701 agacaaaaca agttggtttt gtaggtggta tcgaatctga agttatctct cgttttgaag
    14761 caggattcaa ggctggtgtt gcgtcagtag acccatctat caaagtccaa gttgactacg
    14821 ctggttcatt tggtgatgca gctaaaggta aaacaattgc agccgcacaa tacgcagccg
    14881 gtgcagatat tgtttaccaa gtagctggtg gtacaggtgc aggtgtcttt gcagaggcaa
    14941 aatctctcaa cgaaagccgt cctgaaaatg aaaaagtttg ggttatcggt gttgaccgtg
    15001 accaagaagc agaaggtaaa tacacttcta aagatggcaa agaatcaaac tttgttcttg
    15061 tatctacttt gaaacaagtt ggtacaactg taaaagatat ttctaacaag gcagaaaaag
    15121 gagaattccc tggcggtcaa gtgatcgttt actcattgaa ggataaaggg gttgacttgg
    15181 cagtaacaaa cctttcagaa gaaggtaaaa aagctgtcga agatgcaaaa gctaaaatcc
    15241 ttgatggaag cgtaaaagtt cctgaaaaat aatggatgga agtcatttct taggaagcgg
    15301 ccaagggccg cttttttaag agttgagaca aagtcatttt gtctcagtaa agcttgctac
    15361 tagacaaact agcaagtttt attgaaataa aataagactc tgaaaggaag agcacatggc
    15421 acacgaaaat gtcattgaga tgcgtgatat taccaaggtg tttggtggat ttgttgccaa
    15481 cgacaaaatc aacttgcacc tacgaaaagg tgaaattcat gcacttttag gagaaaatgg
    15541 ggctggtaag tccacgctaa tgaacatgtt agcaggcctt cttgaaccaa ctagtggtga
    15601 aatcgcggtc aacggtcaag ttgtcaatct cgactcccca tctaaagcag ctagcttggg
    15661 aatcgggatg gttcaccagc actttatgtt ggttgaagcc ttcacagtgg ctgaaaacat
    15721 cattttaggt agtgaattga ctaaaaatgg tgtgctagat atcgctggag ctagcaaaga
    15781 aatcaaggct ctttctgaac gttatggctt agctgttgac ccttctgcca aggtagtaga
    15841 tatctcagtt ggagcccaac aacgtgtaga aattttaaaa acactttata ggggggctga
    15901 tatccttatc tttgacgaac caacggctgt tttgactcca tcagaaattg atgagttgat
    15961 ggctattatg aaaaatcttg tcaaagaagg aaaatcaatt atcttgatta cccacaaatt
    16021 ggatgaaatt cgcgcagttt ctgaccgtgt tacagttatc cgtcgtggga aatcaattga
    16081 aaccgttgaa attgcagggg ctaccaatgc tgatttggcg gaaatgatgg taggacgttc
    16141 tgtttccttt aaaacagaga agcaagcctc taaaccaaaa gaagtggttt tgtctatcaa
    16201 agatttggtg gtcaatgaaa accgtggtgt tccagctgtt aaaaatctgt ccttggatgt
    16261 tcgtgctgga gagattgttg gtattgcggg gattgatgga aatggtcagt ctgaactgat
    16321 tcaagccatt acaggtcttc gtaaggttga atctggtagc attgagctaa aaggagattc
    16381 aattgtaggc ttgcacccac gtcagattac agaactaagt gttgggcacg ttccagaaga
    16441 ccgtcaccgt gatggcttga ttttggaaat gatgatatct gaaaatattg cccttcaaac
    16501 ctactataaa gaaccacata gtaaaaatgg aattttgaat tattcaaata ttacttctta
    16561 tgctaaaaag ctgatggaag agtttgatgt tcgcgctgcc agtgaattag ttcctgcagc
    16621 tgcactctca ggaggaaatc aacaaaaagc aattattgct cgtgaaattg atcgagatcc
    16681 tgatctcctt atcgttagcc agccaactcg tgggttggat gtcggtgcca ttgagtatat
    16741 ccacaaacgc ttgattgaag agcgtgataa tggcaaggct gtccttgttg tcagctttga
    16801 attggatgaa attttaaacg tctcagaccg tattgccgtt atccacgatg gtaagattca
    16861 aggtattgta tcaccagaaa caaccaataa acaaggactt ggtgtcttga tggctggtgg
    16921 aaacttggga aaggagaaga gtgatgtcta aaaaattaca acaaatttcg gttcccttga
    16981 tttctgtatt cctaggaatt ttactcggag ccattgtcat gtggatcttc ggttatgatg
    17041 ctatttgggg ctacgaagaa ttgttctata cagcctttgg cagtctgcgt gggattggag
    17101 aaatcttccg tgctatgggt cctctggtct tgattggtct tggttttgcg gttgccagtc
    17161 gagctggttt ctttaacgtc ggacttcctg gtcaggcttt ggcaggttgg attctcagtg
    17221 gttggtttgc cctgtcgcat ccagatatgc cccgtccctt gatgattcta gcaaccatcg
    17281 tgattgcctt gattgctggt gggattgtcg gagcgattcc aggtattctt agggcctatc
    17341 tagggacgtc agaggttatt gtaaccatca tgatgaacta cattgtcttg tatgtaggga
    17401 atgcctttat ccatgctttc cctaaagact tcatgcaaag tacagattcg accattcgtg
    17461 ttggggctaa tgcaacctat cagacacctt ggttggctga gttgactggt aactcacgga
    17521 tgaatattgg tattttcttt gccatcattg ccgttgcagt tatttggttc atgctcaaga
    17581 aaacaactct tggttttgaa atccgtgcag ttggtcttaa tccacatgct tcagaatatg
    17641 ctggtatttc tgccaagcgg actattatcc tatctatgat tatttcaggt gccttggcag
    17701 gtcttggtgg agctgttgaa ggtttgggaa ccttccagaa cgtctatgtt caaggttcgt
    17761 cattagctat cggatttaac ggaatggcgg ttagtttgct tgcggccaac tcaccaattg
    17821 gtatactctt tgcagccttc ctatttggcg ttctccaagt tggggctcct ggtatgaatg
    17881 cggcgcaggt accatctgag cttgtcagca ttgtaacagc gtctattatc ttctttgtca
    17941 gtgttcatta ccttatcgaa cgctttgtca aaccgaaaaa acaagttaaa ggaggtaagt
    18001 aaagatgtct attataacct tgctccccct cttggtgtct tctatgctga tttactcagc
    18061 acctctcatc tttacaagta tcggtggtgt tttctctgaa cgtggtggtg tggtaaacgt
    18121 tggccttgaa ggaattatgg ttatgggtgc cttttctgga gttgtcttta accttgaatt
    18181 tgcagaacaa tttggagcag caactccatg gctatccttg cttgtagcag gattggttgg
    18241 tagtgttttc tctatcatcc acgcagcagc gacggttcat ttccgtgcag accatgttgt
    18301 cagcggtacg gtattgaact tgatggcgcc tgccttggct gttttcttag ttaaagttct
    18361 ttataacaaa ggacaaaccg acaacctaag tcaaactttt ggacgctttg atttcccagt
    18421 cttggcaaat atcccagtga ttggtgatat cttcttcaag tcaactagtc tacttggtta
    18481 tctggcgatt gccttctcat tccttgcttg gtttattctc tttaagactc aatttggtct
    18541 tcgtctccgc tctgtcggtg aacatcctca agcagcggat accttgggaa tcaacgtcta
    18601 caagatgaga tatttagggg ttattatttc aggttttcta ggtggaattg gcggagcgat
    18661 ttatgcgcaa tcaatctcag ttaacttctc agtgacaact attgttggac ctggatttat
    18721 cgcccttgct gcgatgatct ttgggaaatg gaatccaatc ggtgctatgc tttctagtct
    18781 cttctttgga ctttcacaaa gtttggctgt tatcggttct caattgccgt tcctacaagg
    18841 agtgccagcg gtttatcttc aaattgcacc ttatgttttg acaattcttg tcttagcagc
    18901 cttctttgga aaagcagtcg caccaaaagc agatggtatc aactacatca aatcaaaata
    18961 agcatacaaa aaaacgtcag tccaatgact gaactgcacc ccaaaagtta gacagaaaaa
    19021 atctaacttt tggggtgttt ttattatgaa attaagttat gatgataaag ttcagatcta
    19081 tgaactaaga aagcaaggat atagcttaga gaagctttca aataaatttg ggataaataa
    19141 ttctaatctt aggtatatga ttaaattgat tgatcgttac ggaatagagt tcggcaaaaa
    19201 aggaaaaaat cgttactatt ctcctgattt aaaacaagaa atgattcata aagtctgaca
    19261 tgaaggctgg actaaagata gagtttctct tgaatacggt ctcccaagtc gtacgatact
    19321 tcttaactgg ctagcacaat acaggaaaaa cgggtatact attgttgaga aaacaagagg
    19381 gagagtacct aaaatgggac gtaagccaag aacgagacct gaagagagga cagaattaga
    19441 acgtcttcaa gcagaaaatg agtacctgag agcggagaat gccatcctaa aaaagttaag
    19501 agaactccga ttgaaggagg aaaaagagaa agaagaaaga cagaaattgt tcaagaatta
    19561 atgactgagt tttcgttaga tcttcttcta aaagccatta aactagctcg ttggacctac
    19621 tactatcact tgaaacagct agacaaaaca gataaggacc aagagcttaa agctgaaatt
    19681 caatccattt ttatcgaaca caaaggaaat tatgcttatc gccgggttca tttagaacta
    19741 agaaatcgtg cttatctggt aaatcataaa agagttcaag gcttgataaa agtactcata
    19801 atttagaaca agtacaaaca atgttggaac aggcattcaa agagaagcac tacgagaata
    19861 cgattctcca tagtgaccaa ggctggcaat atcaacacga ttcttatcat cggttcctag
    19921 agagtaaggg aattcaagca tccatgtcac gtaagggtaa cagcccagac aatggtatga
    19981 tggagtcctt ctttgggatt ctgaaatcgg aaatgtttta cggttatgag aagtcgtttc
    20041 agtcgtttaa gcaattggaa caagctattg tagactatat tgattactac aacaacaaac
    20101 gaattaaggt aaaactaaaa ggacttagtc ctgtgcagta cagaactaaa tcctttggat
    20161 aaattatttg tctaactgtt tgggggcagt acagaactgg cgttttattt tttaggatct
    20221 tgatgagtta ggttcaatcc ccaagggacc aaattttcag ttttattttt gatacgagct
    20281 atattgtcct tatgacgaat gataatcaaa ctagcaagtg ctaagataat agcgatgaag
    20341 agagagtcat agttactcag gataaaacca aaaagtggaa agagcagaac cccgataaca
    20401 gccgcgatcg atgctgtgac actagacagt gaaatcatac tgccaagata gagagctcca
    20461 aagaagataa tcgcaaggta gagacagaag ataggcgcaa atccgaaaat cactccagca
    20521 ctggttgcga cagccttacc acctttaaat cctgcaaaga tagggaaggt atggccgata
    20581 acagccaaaa gtccaaagat gagaggagaa acgccttgta gatgaaaaat aatcggaagc
    20641 agcgttgcta gggttccttt gaaaaagtca atcacaaagg ttgccatacc agctttctta
    20701 cctaaaatgc ggaaggtatt ggtcgttcca gtgttaccag aaccatgctc gcgtagattg
    20761 atttgaaaga atacttgtcc aatccagaga ccagatggaa tcgaacccag cagataggct
    20821 aggattaata aaattattgt aatcatactc ctattatatc atgaattggg aaagaaaagc
    20881 agagaatctc tgctgaaatt gtcacatcgg agaaagaaaa attttgcaaa atccttggaa
    20941 aacctgtaga atagtaaaga tgaacgaata ggaggttcct tgtgtcaaaa aaggaaatca
    21001 atattaacaa ttataatgat gatgctattc aggtgctaga agggttggat gcggtccgaa
    21061 aacgtccagg gatgtatatt ggatcgaccg atggcgctgg tcttcatcac ctagtttggg
    21121 aaatcgttga taatgcagtc gatgaagcct tgtctgggtt tggtgatcgt attgatgtaa
    21181 ctatcaataa agacggtagt ctaacggttc aagaccatgg acgtgggatg ccgacaggta
    21241 tgcacgctat gggaattcca actgttgagg ttatctttac cattcttcat gccggaggga
    21301 aattcggtca aggtggctat aagacatcag gtggacttca cggagtgggt tcttccgttg
    21361 ttaacgccct ttctagctgg ttagaagttg aaattacccg tgatggcgca gtttacaagc
    21421 aacgttttga aaatggtgga aaacctgtca cgactttgaa gaaagtcggt acagcaccca
    21481 agtctaaaac aggcaccaaa gttactttta tgcctgacgc gactatcttt tctacgacag
    21541 atttcaagta caataccatt tcagagcgcc ttaatgaatc agcctttctc ttgaaaaatg
    21601 tgaccttgtc tttaacggac aagcgatcag atgaagcgat tgagttccac tatgagaatg
    21661 gagtacaaga ttttgtttct tatctcaacg aagataagga aatcttgacg ccagttcttt
    21721 actttgaagg ggaagacaat ggttttcaag tggaagtagc cctccagtac aatgacggat
    21781 tctcagataa cattctatcc tttgtcaata acgttcgcac caaggacggt ggaacgcacg
    21841 agacaggact caagtctgcc attaccaagg tcatgaatga ctatgcacgt aaaacaggtc
    21901 ttctcaagga aaaagataaa aaccttgaag gttcagacta tcgtgaggga ctagcggccg
    21961 ttctttctat cttagttcct gaagaacact tgcagtttga aggacagacc aaggataaac
    22021 taggaagccc cttagctcgc ccagttgtgg atggaatagt ggctgataag ttgacctttt
    22081 tccttatgga aaatggggaa ttagcttcta acctcatccg caaggctatc aaggcccgtg
    22141 atgctcgtga agcagcacgt aaggcgcgtg atgagagccg aaatgggaag aaaaacaaga
    22201 aagataaggg cttgttgtct gggaaattga ccccagccca atctaagaat cctgctaaga
    22261 atgaactcta tctagttgag ggggactctg ccggtggttc tgccaaacaa ggtcgtgacc
    22321 gcaagttcca ggctattcta cctcttcgtg gtaaggttat caatacagcc aaggccaaga
    22381 tggcggatat cctcaaaaat gaagagatca ataccatgat ttataccatt ggtgcgggtg
    22441 ttggagcaga cttctctatt gaagatgcca actatgataa gatcattatc atgaccgatg
    22501 cggataccga cggtgcccat atccagacct tgctcttgac atttttctac cgttacatgc
    22561 gtccgctagt cgaggcaggt catgtctata ttgccctccc acctctttac aagatgtcca
    22621 aaggtaaagg caagaaagaa gaagtggcct acgcttggac ggacggagaa ctagaagaac
    22681 tacgtaaaca gttcggtaaa ggcgctaccc tccaacgata caaaggactt ggtgagatga
    22741 atgcggacca gctctgggaa acaaccatga acccagaaac acgtaccctc atccgtgtca
    22801 caattgaaga tttagcgcgc gccgaacgtc gcgtcaatgt tctcatggga gataaggtag
    22861 aaccacgccg taaatggatt gaagataatg tcaagtttac gctagaagaa gcgacagtgt
    22921 tttaatgaaa gaaaataata tgttagtaaa ctggaaatta gagtcggatg tgaatgacta
    22981 tgtgaaaaag cagtttgaaa atcttggttt gaaaaaattg cagaattatt aatgaagaat
    23041 cttctatgag tgcttatctc aaagaggcgt ttaagggagc ggctaagaca caaactaaga
    23101 ctaattttgg aaaaccagat tttcatattg aaaaatacaa acaggatagt ttggttactt
    23161 atcgtaactg aacacgggac gaattcccgt aaaatatctt ttactgcata aaaacctact
    23221 ctacattctt tgaaaggagt tgaacacgcc ctagatattg tgtgaaaaag ataaattctc
    23281 ttgtgagttt gcttacttca agaattttct attttcactt ggtattttat gggctttgta
    23341 tcttatgtct aacattcaaa acatgtccct ggaggacatc atgggagagc gctttggtcg
    23401 ctactccaag tacattattc aagaccgggc tttgccagat attcgtgatg ggttgaagcc
    23461 ggttcagcgc cgtattcttt attctatgaa taaggatagc aatacttttg acaagagcta
    23521 ccgtaagtcg gccaagtcag tcgggaacat catggggaat ttccacccac acggggattc
    23581 ttctatctat gatgccatgg ttcgtatgtc acagaactgg aaaaatcgtg agattctagt
    23641 tgaaatgcac ggtaataacg gttctatgga cggagatcct cctgcggcta tgcgttatac
    23701 tgaggcacgt ttgtctgaaa ttgcaggcta ccttcttcag gatatcgaga aaaagacagt
    23761 tccttttgca tggaactttg acgatacgga gaaagaacca acggtcttgc cagcagcctt
    23821 tccaaacctc ttggtcaatg gttcgactgg gatttcggct ggttatgcca cagacattcc
    23881 tccccataat ttagctgagg tcatagatgc tgcagtttac atgattgacc acccaactgc
    23941 aaagattgat aaactcatgg aattcttgcc tggaccagac ttccctacag gggctattat
    24001 tcagggtcgt gatgaaatca agaaagctta tgagactggg aaagggcgcg tggttgttcg
    24061 ttccaagact gaaattgaaa agctaaaagg tggtaaggaa caaatcgtta ttactgagat
    24121 tccttatgaa atcaataagg ccaatctagt caagaaaatc gatgatgttc gtgttaataa
    24181 caaggtagct gggattgctg aggttcgtga tgagtctgac cgtgatggtc ttcgtatcgc
    24241 tatcgaactt aagaaagacg ctaatactga gcttgttctc aactacttat ttaagtacac
    24301 cgacctacaa atcaactaca actttaatat ggtggcgatt gacaatttca cacctcgtca
    24361 ggttgggatt gttccaatcc tgtctagcta catcgctcac cgtcgagaag tgattttggc
    24421 gcgttcacgc tttgacaaag aaaaggctga gaaacgtctc catatcgtcg aaggtttgat
    24481 tcgtgtgatt tcgattttgg atgaagtcat tgctcttatc cgtgcttctg agaataaggc
    24541 ggacgccaag gaaaacctca aagttagcta tgattttacg gaagaacagg ctgaggctat
    24601 cgtaactttg caactgtacc gtttgaccaa taccgatgtg gttgtcttgc aggaagaaga
    24661 agcagagctt cgtgagaaga ttgctatgct ggcggctatt attggtgatg aaaggactat
    24721 gtacaatctc atgaagaaag aacttcgtga ggtcaagaag aaatttgcaa ctcctcgttt
    24781 gagttcttta gaagacactg cgaaagcaat tgagattgat acagctagtc ttatcgctga
    24841 ggaagatacc tacgtcagcg tgaccaaggc aggttacatc aagcgtacca gtccacgttc
    24901 ctttgcggct tccaccttgg aagaaattgg caagcgtgat gatgaccgtt tgatttttgt
    24961 tcaatctgcc aagacaaccc agcacctctt gatgttcaca agtcttggaa atgtcatcta
    25021 cagaccaatc catgagttgg cagatattcg ttggaaggac atcggagagc atctgagcca
    25081 aaccatcaca aactttgaaa cgaatgaaga aatcctttat gtggaagtac tggatcagtt
    25141 tgacgatgcg acaacctact ttgcagcgac tcgccttggt caaatcaaac gggtagagcg
    25201 aaaagaattc actccatggc ggacctatag atctaagtct gtcaagtatg ctaagctcaa
    25261 agacgataca gatcagattg tagcagtggc tccgattaaa ctagatgatg ttgtcttggt
    25321 tagtcaaaat ggttatgccc tgcgtttcaa tatcgaagag gttccggttg tcggtgctaa
    25381 ggcagcaggt gtcaaggcta tgaatttgaa agaagatgat gtcctccaat ctggctttat
    25441 ctgtaatact tcgtccttct acctcttgac ccagcgtgga agcttgaaac gtgtttccat
    25501 tgaggaaatt ctagcaacca gccgtgccaa acgaggatta caggtcttgc gtgagttgaa
    25561 aaacaaaccg catcgtgtct tcttggcagg agcagttgca gagcaaggat ttgttggcga
    25621 tttcttcagt acggaagtgg atgtgaacga ccaaactctg cttgtccaat ccaataaagg
    25681 aacaatctat gaaagccgat tgcaagactt gaacttgtca gaacgcacta gcaatggaag
    25741 cttcatttct gacacgattt cagatgaaga agtttttgac gcttatcttc aggaagtagt
    25801 tactgaagat aaataagtga aatgaagaat cagttctaag agctggtttt tattggagaa
    25861 attttctgaa aattacaaaa tatacttgct attttagaaa aatagtgtag aatataagaa
    25921 ataggttttt agaataagga gtggaatatg acagtaacga ttgattggga aaacctcggt
    25981 ttttcctata tgaaattacc ttatcgctat cttgctcatt tcaaaaatgg acaatgggat
    26041 caaggagagc ttacagagga tgcaactttg catatttcag agtcttctcc aagtcttcac
    26101 tatggacaac aagcatttga aggtttgaaa gcttatcgta ctaaggatgg cagtgttcaa
    26161 ctgttccgtc ctgatgaaaa tgctaaacgc ctgcaacgta catgtgaccg tctcttgatg
    26221 ccacaagttc cgacagacat gtttgtagaa gcttgtaaag cagttgtccg tgcgaatgaa
    26281 gaatacgtac caccatacgg aataggtgga accttatatc ttcgccctct tttgattggt
    26341 gtcggagata ttatcggggt aaaaccggca gaagagtaca ttttcaccat ctttgctatg
    26401 ccagttggaa attactttaa aggtggtttg gtcccaacca acttcttgat tcaggatgag
    26461 tacgaccgtg cagcaccaaa tggtacaggt gcggctaagg ttggtggaaa ctatgctgca
    26521 agtctcttac caggaaaaat ggccaagtca cgtcatttct cagatgttat ctatctggac
    26581 ccatcaactc atacaaagat tgaagaagtc ggatcagcta acttctttgg aattacagct
    26641 gataatgaat ttgtaacacc attgagtcca tctatcttgc catctattac caagtattcc
    26701 ttgctttatt tggcagaaca ccgcttggga ttaactccta ttgagggtga tgttccaatt
    26761 gataatcttg accgttttgt agaggcaggt gcctgtggta cagcagcggt tatttctcca
    26821 attggaggta ttcaacatgg tgatgatttc catgtattct atagtgaaac agaagtaggt
    26881 cctgtgacgc gtaaattata taatgaattg acgggtattc agtttggcga tattgaagcg
    26941 ccagaaggtt ggattgtaaa agtagattaa aataaaccga aggagatttt ttatgaaata
    27001 gaaaaagtgg ctcttaacag caggagtggt cctgagcacg tcagctattt tagtggcttg
    27061 tggaaaaact gataaagaag ccgatgcacc gacaacattt tcttatgtct atgcagtaga
    27121 tccagcatca ttgggctaca gtatagcgac tcgaacatcg acgacagacg ttattggaaa
    27181 tgttattgat ggtttgatgg aaaatgataa atacggcaat gttgctcctt ctcaaaaaga
    27241 ctatgatttg aatagtacag gatgggctcc aagctatcaa gatccagcgt cttacttgaa
    27301 tattatggat ccaaaatctg gttctgccat gaaacacctt ggtattacga aaggaaaaga
    27361 taaggatgtt gtagctaaac ctggtttgga taaatataag aaattgttag aagatgctgt
    27421 ttctgagacc actgacctag agaagagata tgaaaaatat gccaaagctc aagcttggtc
    27481 gacagatagt tcattattga tgccaacagc ttcatctggt ggttctccag ttgtaagtaa
    27541 cgtagtacca ttctcaaaac catactcaca agttggtatt aagggggatc catatatctt
    27601 taaaggaatg aaattgcaaa aagatattgt tacaacaaaa gaatataacg aggtttttaa
    27661 aaaatggcaa aaagaaaaat tggaatccaa tagcaaatac caaaaagaac tagaaaaaca
    27721 cattaaataa ggaatggtat tgatcttgat aaaattttaa aaatactgtc attttgaata
    27781 taaaggagtt tgatatggag tggattagat taataggaat agcaatcatt gttgtgggtt
    27841 ttattttaaa atttgataca attgcaacag tagtcttagc tggtttggtt acagctttag
    27901 tttcaggtgt ttctctcgtt gaatttttgg agattttggg aaaagaattt agcaatcagc
    27961 gagtgctcac gatttttatg gttaccttgc ctcttgtggg gctgtcagaa acctttggac
    28021 tcaagcaacg atcaatcgat ttgattcgaa agattaaagg tctgacagtt ggaaacttct
    28081 atacagttta tttctttatt cgagagttag ctggtttctt ttcaattcgt ctaggaggac
    28141 accctcagtt tgtcagacct ttggttcagc ctatgggaga agcagctgca gagtctcaat
    28201 taggtagaaa gttaacagag gttgaagatg agacaataaa agcgcgtgcg gcagcgaatg
    28261 aaaattttgg aaatttcttt gctcaaaata cgtttgtagg tgctggggga gtcctcttga
    28321 tagggggaac attagatcag ttaggctatg aaagcaatta tgcagggatt gcttctacat
    28381 ctattattgt tgctgttata acacttattg tagtggggat ttacaattat ttatttgata
    28441 aaaaattgat atcaaaaaag actaggggag gagaacaaaa atgacagagt tggcaaagca
    28501 actattagag ttgacctata ttgtgattgg ttgtcaattt ctccatacag cctattgtag
    28561 ttataaagat aaaacaaacc cagttcgact tgggacatct gcattttgga ctctattgtc
    28621 tattacgttt ataggtggtt cctatatgcc aaatatgagt attggtatta ttgtaatcct
    28681 attatcgctg ttaacattgt ttaagcaagt ccgtatcgga accttgccat ccttagatga
    28741 aatgaaagcc aatattgaat ctaacaggtt gaaaaataaa atttttattc cagttatgct
    28801 gatggcaata cttgcgttgg tcttagcgca aatgattcca gaatttagca agatttcgat
    28861 tagccttgcc gccttgtttg ctacaatttc tgttcttgtg attaccaata gtcaccctaa
    28921 gagtctgtta tcagaaaata atcgaatgac tcagcaagtt tcaacaagtg gtattgttcc
    28981 tcaattatta ggggctttgg gggctatttt tactgtagca ggtgttggtg atgttatctc
    29041 tcatctgatt agcggtattg ttccttcaga tagtcgcttt ataggagttt tggcctatgt
    29101 tcttggaatg gttctattca caatgattat gggaaatgct tttgcagcat tcaccgttat
    29161 tacagcaggt gttggagttc cctttgtatt tgctctggga gctaatccaa ttgtggctgg
    29221 tgctcttgcc atgacagcag gttattgtgg gaccttattg accccaatgg ctgctaattt
    29281 taacgctcta ccagcagcat tgatggatat gaaagatcag aatggcgtta taaaggctca
    29341 agcaggtgtt gctctagtaa tgattgttat tcacatattc ttaatgtact ttctcgcatt
    29401 ttagtaaagg aaaataaaat gaaaatattg gttacaggtt ttaatccttt tggaggtgaa
    29461 aagattaatc cagctttgga ggctgtaaaa ttattaccat ctgagattaa tggggctgaa
    29521 gttcgctggg tagaaattcc aacggttttt tataagtcgt cagaagtttt agaggcagaa
    29581 atattacgat atcaaccaga tgctgtactt tgtattggac aagcaggcgg caggaccggc
    29641 ttaacacctg aacgagtggc tattaatcaa gatgatgctc gcatacctga taacgaaggc
    29701 aatcaaccaa ttgatacacc gattcgtatt gatggagcat cggcctattt tagtagttta
    29761 cctatcaaag cgatggtaca agctatcaaa aaacagggac ttccggcagt tgtatccaat
    29821 agtgcaggaa cctttgtttg caatcatttg atgtaccaag ctctttattt agtggataaa
    29881 aaattcccta atatgagagc aggtttcatg catattccat atatgatgga acaagtagta
    29941 aataagccga atactgcagg aatgagtcta tgtgatattg taagaggcat agaggtagct
    30001 attgaagcta ttgtagacta caaagataag gatttgcagt tagtaggcgg tgagactcac
    30061 tgataaccta aaaaggatag tcaattatgc ttgtttacta actattaact atgctaaatc
    30121 aattgaggtt gtttacataa aactctatat cagagaagcc tgatatagag ttttttcttg
    30181 ctagttttag aattttcttg taaaatagaa aaagtgaaga gaggtatgaa atgagcaaga
    30241 aagataaaaa aatcgaaatt caagtagcgg atgccaaagt taatgttggt aaagacagtt
    30301 ttgaaggtta tacattgact atcggtaaaa aagttatcgg agaaattgcc gaattagacg
    30361 gacaatttgc cattataaag aatgggaatg tcgatagttt ttataaaaaa ttggaaaaag
    30421 ctgtggaaat tttgattgaa aattataatt tagcaaaata agtcttgttt ttttgaaatt
    30481 ttcatgatat aatagtccat gttgattgta ggagagatag cgaagaggct aaacgcggcg
    30541 gactgtaaat ccgctccttc gggttcgggg gttcgaatcc ctctctctcc atttcattaa
    30601 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
    30661 cagctacccc agttcttagg taataatcaa gataaaaagc aaaatatctt agggtatttt
    30721 atttttataa ttgaaagacg tgaatgatat gaacatgtcc ttgcgggtgc ttaggaaaaa
    30781 aattataagt atgtcaagtt taagaaaaac ttgattgttg gaggattttt tagatgaacg
    30841 aatttgaaga tttgctaaat agcgttagtc aagttgagac tggtgatgtt gttagtgctg
    30901 aagtattgac agttgatgcg actcaagcta acgttgcaat ctctggaact ggtgttgaag
    30961 gtgtcttgac tcttcgcgaa ttgacaaacg atcgtgatgc agatatcaat gactttgtta
    31021 aagtaggaga agtattggat gttcttgtac ttcgtcaagt agttggtaaa gatactgata
    31081 cagttacata ccttgtatct aaaaaacgcc ttgaagctcg caaagcatgg gacaaacttg
    31141 ttggtcgcga agaagaagtt gttactgtta aaggaacgcg tgccgttaaa ggtggacttt
    31201 cagtagaatt tgaaggtgtt cgtggattta tcccagcttc aatgttggat actcgtttcg
    31261 tacgtaatgc tgagcgtttt gtaggtcaaa aatttgatac taaaatcaaa gaagttaacg
    31321 ctaaagaaaa ccgcttcatc ctttcacgtc gtgaagttgt tgaagcagct actgcagcag
    31381 ctcgcgctga agtattcggt aaattggctg ttggtgatgt tgtaactggt aaagttgctc
    31441 gtatcacaag cttcggcgct ttcgtcgacc ttggtggtgt tgacggattg gttcacttga
    31501 ctgaattgtc acatgaacgt aacgtatcac caaaatcagt tgtaactgtt ggtgaagaaa
    31561 ttgaagtgaa aatccttgat cttaacgaag aagaaggacg tgtatcactt tcacttaaag
    31621 caacagtacc aggaccatgg gatggcgttg agcaaaaatt ggctaaaggt gatgtagtag
    31681 aaggaacagt taaacgtttg actgacttcg gtgcatttgt tgaagtattg ccaggtatcg
    31741 atggacttgt tcacgtatca caaatttcac acaaacggat tgaaaatcca aaagaagctc
    31801 ttaaagttgg tcaagaagtt caagttaaag ttcttgaagt taacgcagat gcagaacgcg
    31861 tgtcactttc tattaaagct cttgaagaac gtccagccca agaagaagga caaaaagaag
    31921 aaaaacgtgc tgctcgtcca cgtcgtccaa gacgtcaaga aaagcgtgat ttcgaacttc
    31981 cagaaacaca aacaggattt tcaatggctg atttgtttgg tgatatcgaa ctttaatcaa
    32041 attgaaaatt cacaaaatcc tttgtttact aaacaaggga tttttct
//
LOCUS       DAVLCS010000026        28496 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLCS010000026 DAVLCS010000000
VERSION     DAVLCS010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28496
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.026"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(254..550)
                     /locus_tag="VXC78_001313"
     CDS             complement(254..550)
                     /locus_tag="VXC78_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEV0583392.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(1081..1974)
                     /locus_tag="VXC78_001314"
                     /pseudo
     CDS             complement(1081..1974)
                     /locus_tag="VXC78_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(2728..2958)
                     /gene="blpU"
                     /locus_tag="VXC78_001315"
     CDS             complement(2728..2958)
                     /gene="blpU"
                     /locus_tag="VXC78_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0583393.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
     gene            complement(3161..3451)
                     /locus_tag="VXC78_001316"
                     /pseudo
     CDS             complement(3161..3451)
                     /locus_tag="VXC78_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(3497..3730)
                     /locus_tag="VXC78_001317"
     CDS             complement(3497..3730)
                     /locus_tag="VXC78_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0583394.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(3736..4728)
                     /gene="plsX"
                     /locus_tag="VXC78_001318"
     CDS             complement(3736..4728)
                     /gene="plsX"
                     /locus_tag="VXC78_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV0583395.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(4725..5495)
                     /gene="recO"
                     /locus_tag="VXC78_001319"
     CDS             complement(4725..5495)
                     /gene="recO"
                     /locus_tag="VXC78_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV0583396.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDDRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(5492..6661)
                     /locus_tag="VXC78_001320"
     CDS             complement(5492..6661)
                     /locus_tag="VXC78_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0583397.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            6810..7820
                     /locus_tag="VXC78_001321"
     CDS             6810..7820
                     /locus_tag="VXC78_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HEV0583398.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(8103..8540)
                     /locus_tag="VXC78_001322"
     CDS             complement(8103..8540)
                     /locus_tag="VXC78_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV0583399.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(8625..11258)
                     /gene="polA"
                     /locus_tag="VXC78_001323"
     CDS             complement(8625..11258)
                     /gene="polA"
                     /locus_tag="VXC78_001323"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV0583400.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEYGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPDIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            11514..11864
                     /locus_tag="VXC78_001324"
     CDS             11514..11864
                     /locus_tag="VXC78_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0583401.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            12079..12195
                     /locus_tag="VXC78_001325"
                     /pseudo
     CDS             12079..12195
                     /locus_tag="VXC78_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            12188..12421
                     /locus_tag="VXC78_001326"
     CDS             12188..12421
                     /locus_tag="VXC78_001326"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583402.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            12548..12829
                     /locus_tag="VXC78_001327"
                     /pseudo
     CDS             12548..12829
                     /locus_tag="VXC78_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(12963..13931)
                     /locus_tag="VXC78_001328"
     CDS             complement(12963..13931)
                     /locus_tag="VXC78_001328"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0583403.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVAVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(14076..14859)
                     /locus_tag="VXC78_001329"
                     /pseudo
     CDS             complement(14076..14859)
                     /locus_tag="VXC78_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(14884..15381)
                     /locus_tag="VXC78_001330"
     CDS             complement(14884..15381)
                     /locus_tag="VXC78_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV0583404.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     AVVEL"
     gene            complement(15454..16815)
                     /gene="radA"
                     /locus_tag="VXC78_001331"
     CDS             complement(15454..16815)
                     /gene="radA"
                     /locus_tag="VXC78_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV0583405.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(16829..17344)
                     /locus_tag="VXC78_001332"
     CDS             complement(16829..17344)
                     /locus_tag="VXC78_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0583406.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(17346..17789)
                     /locus_tag="VXC78_001333"
     CDS             complement(17346..17789)
                     /locus_tag="VXC78_001333"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV0583407.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     DLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            18094..18243
                     /locus_tag="VXC78_001334"
     CDS             18094..18243
                     /locus_tag="VXC78_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583408.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            18385..18564
                     /locus_tag="VXC78_001335"
     CDS             18385..18564
                     /locus_tag="VXC78_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583409.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(18784..19149)
                     /locus_tag="VXC78_001336"
                     /pseudo
     CDS             complement(18784..19149)
                     /locus_tag="VXC78_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            19169..19336
                     /locus_tag="VXC78_001337"
     CDS             19169..19336
                     /locus_tag="VXC78_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HEV0583410.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            complement(19491..19694)
                     /locus_tag="VXC78_001338"
     CDS             complement(19491..19694)
                     /locus_tag="VXC78_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583411.1"
                     /translation="MRPKRYPYSGQKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYEAIHDTSQVTQ"
     gene            complement(19717..19908)
                     /locus_tag="VXC78_001339"
     CDS             complement(19717..19908)
                     /locus_tag="VXC78_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0583412.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            20480..20848
                     /locus_tag="VXC78_001340"
     CDS             20480..20848
                     /locus_tag="VXC78_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0583413.1"
                     /translation="MFETFEKIKELAKKRGKALGQVEEDLGYGRNTLYKIKNSTPNAE
                     RIAEIANYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            20848..21081
                     /locus_tag="VXC78_001341"
     CDS             20848..21081
                     /locus_tag="VXC78_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583414.1"
                     /translation="MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLTREDIA"
     gene            21081..21344
                     /locus_tag="VXC78_001342"
     CDS             21081..21344
                     /locus_tag="VXC78_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0583415.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            21357..21733
                     /locus_tag="VXC78_001343"
                     /pseudo
     CDS             21357..21733
                     /locus_tag="VXC78_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            21750..22820
                     /locus_tag="VXC78_001344"
     CDS             21750..22820
                     /locus_tag="VXC78_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HEV0583416.1"
                     /translation="MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGY
                     DIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYF
                     VTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFD
                     IDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIV
                     KGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEAEEIVEVTDEIITTPAELEVY
                     TVVKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFP
                     VSTPLEVANYANEILEVIKKFS"
     gene            22875..24016
                     /locus_tag="VXC78_001345"
                     /pseudo
     CDS             22875..24016
                     /locus_tag="VXC78_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(24099..24192)
                     /gene="ffs"
                     /locus_tag="VXC78_001346"
     ncRNA           complement(24099..24192)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VXC78_001346"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(24225..24692)
                     /locus_tag="VXC78_001347"
     CDS             complement(24225..24692)
                     /locus_tag="VXC78_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV0583417.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(24893..26179)
                     /locus_tag="VXC78_001348"
     CDS             complement(24893..26179)
                     /locus_tag="VXC78_001348"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV0583418.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(26410..26646)
                     /locus_tag="VXC78_001349"
     CDS             complement(26410..26646)
                     /locus_tag="VXC78_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV0583419.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            26912..27709
                     /locus_tag="VXC78_001350"
                     /pseudo
     CDS             26912..27709
                     /locus_tag="VXC78_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(27744..28496)
                     /locus_tag="VXC78_001351"
                     /pseudo
     CDS             complement(27744..28496)
                     /locus_tag="VXC78_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         9009 a         6448 c         4741 g         8298 t
ORIGIN      
        1 gaaaaatata gtttttcctt atatagaaag tatttatttt tttactttgg ataggcagtt
       61 tcatattata acgattcaaa gtagcgtaat ctactaccaa aaaaagtaaa aataatttcc
      121 cttgaaaagg aagatagctt ttaaaataga ttgacaaact tatgataaca aaaaacaaaa
      181 gggttatccc aataaaatta agataaccta aaatactttc acattctttt ttagaaagta
      241 ttttcatcta gttctaccat agagctgctt tagcagcacc tttctttttc aatatataaa
      301 gaactgttgc tgcaataccc gaaccaatag aacctactcc tgtgattgca cctacaattg
      361 aaattactgc tgtaactgta ctataagcac taatcaaatt gactacagta gcagcagctt
      421 ttgtcgaaat tcctaatgtc ccagccaaca taggaaaaga aacaacacct aagcttaacc
      481 aactaatgac tgctaacatt gctgaaacaa taagaaattt attatgaaat tccattcttt
      541 tagatttcat tttagtgtac tccttttgta tattatgtat gttttattga gagttaattc
      601 gcacatgttg tattcctaac tctcttcaaa tgttcgtcta tattttatac tacttttatt
      661 aacatatcta taataaataa attactacta cattttccta gattatcaaa ttacttttat
      721 atcactaaga ctcaataaaa gataatgtct atttaacttt tatacgatta ctaccttctt
      781 tttagtttac acttcctaca tcataaataa acatactcaa ccctcacaat ctccaaataa
      841 ctcttctata tcattgaaaa ttgagtttca tcctctatac taatgtagga cattccttta
      901 atccaatata agaatacctt gttccattaa tctctacccg atattataga tagaaccaaa
      961 ttcctatact taaaaggaca aataacgttc caaccataat aaacctcctt tctttttgag
     1021 aacgttttct ttataggttt agtatagcaa aaacatgaaa aaaacaacat gacttagaag
     1081 tcaggttgtt gggaaatcta tctgtttttc tgctaaaatt ctctgaacta atacctgatc
     1141 gtctagcaat tctgctagag aaatcgcctt ttcatagaaa ctttctgcct ctaaaatatt
     1201 cttgtctaca aataaagcat attttgcctt tagcaaaaat agatgaggtc ggtaaaaaac
     1261 atgtcttgtt ttagcaataa ttttctcaaa tgtttgaata tatatcagac tatcttctgt
     1321 ctgaatttgg ataaataggc tcagaagaac tttttccatt tgaactaggc tagccttatc
     1381 ttcatattct gaacatagca atactttttg agctaactcc tcaaaatgtt ctttatcttc
     1441 taatcccata gcacaacaaa agaaatacaa ttcaataatc aacaaatcat ttacagaaaa
     1501 atatttcttt tttaataact gctggaaata ttcttccact aaccctaaac cgtaggtcac
     1561 atctgaacta ccataaatat caaaacgagc ttgtgtcaca tccacaatta actgctcttc
     1621 ctcaggcaaa ttctcataat agttttcata tatttcctca agtatagctt cttttcattc
     1681 gattcttccc ttatcagcgt aggtttgaga atgaatcagc tcatctttga gttttaggaa
     1741 tccttttgga atctctataa ccttaacatc cacaatattc tgtaatgata ctccaagttt
     1801 atccgcaatc aataataatt taggaagtgt tgctaaagct tgcccatttt caatacgtgc
     1861 tagctgacga atcgtcaact ctgattcatc accacaaata tctatctgag tttttccaca
     1921 agatcgccta atagttttga ttttataacc aatttcacgt ttcaactcat ccatagtaat
     1981 actccttaag ttgattacaa agatttcttt ttcttcctaa ttcttttgtc aatcatatat
     2041 aaaacgataa gcgaaaacag cggtagaaca atataactct tttcactcat tatcagctga
     2101 aatcccaggg ttgctagtat cttaaagatg aaaatattca tcaaaaatag aaaaacaaat
     2161 actaaaaaat attttaaaac cttcttcatt tcttttcttc aactttccta atttctacac
     2221 ctattttatc gaaaatatat ataaaactcc aaataaacac ttcaactgca ctttttttgg
     2281 caaaaaatag acagaacaaa catcctacct actaaaaata tgatatgaaa ggaaaatgat
     2341 tttttactga caccctaggc aagcttggga caaataaatc attgatagca acatttacga
     2401 catcctattt aaagttcctt caatttctaa tgtccccgct atttctaagc cacctctggt
     2461 atgatctatt cctagtcaga atagataaca ccgttctaaa ttacgattca tagttactcc
     2521 ttttttgact cgttactata agactcctat ttacatgcgc aaaataattt tgattcagat
     2581 tcatcattta tagttttgat tattttttaa cagatttttc tgttttcttc tccgaagact
     2641 ttaaaaattt ttttctaatt aaatcatcca tataaggacc aaatatacca actactaaac
     2701 caataataaa acttttaaaa tccataatta ccaccaacat gtcgctgcat aggccacacc
     2761 tccaagtata gctcctccca cagcaccagt tgctgcacct tgccatgttc ttgttttaat
     2821 tcctagctga agacctcgtg ctgctcctcc tccaacacct gctttggcaa aatctcccca
     2881 attgcatccg ccaccttcaa cgcaagcaag catctcagta tccataattt caaattgtga
     2941 catcgttttt gtattcataa cgaatacctc ttttttattt ttaatatttg tcttgttaca
     3001 aacttgacaa gtttagtata acagtatcta ttaatttttt tcatccaaat cttgaattgg
     3061 catcgaaacg tcttgaatta gcttttttgt ttcaaaatca tctctatttt taaaaaagat
     3121 gttttctaat cactttttta ctattagact tcctgcaaaa ctagaatcct agttcatgat
     3181 tgataatacc agcaatcaaa ttcattcgta atccgaagcg tttacgatga tttcgatagg
     3241 ttgttgaaaa cattttaaac gtttttactt tggcaaagat attctcaacc ttgcttctct
     3301 ccttagatag cgcatgatta caggctttat cttcaactgt tagcggcttg agtttgctgg
     3361 atttacgtgg agtttgtgct tgaggatata tcttcatgag cccttgataa ccactgtcag
     3421 ccaagatttt tccagcttgt ccgatatttc tcatttctaa aaaccatcta cttccgttga
     3481 cttggaactc cgattgctat tttccttgaa tgattttaac cacatctcct acgttttgga
     3541 gttggtcaat ttcttcatcg ctgatttcga tactaaattc atcttccaga gtcaagataa
     3601 actccatcaa gtcaacagaa tccgcatcca aatcgtcttt cagactcaag gattctgtca
     3661 cgacaaagtc ctctccctgt cgctcttgga taatggtcac aatacggtca aaaatttctt
     3721 tttctgtcat ctcttttatt ctcctgaaaa ttcacgcgca gtctgggcaa ccacgtctgt
     3781 ttctagcatg gtacggatct gacgaatcgt actataaaca gccttggcat cgcttgagcc
     3841 atgagtcttg acaacaggtg ccttaacacc aaacaagacc gctccaccaa catctgaata
     3901 attgagctgt tttttcaaac cactgaggct gtccttgaga aggagggcac ctagtttcgc
     3961 tcgaagacca ccacctgtaa tagctgtctt gagcaagccc atgattccca tagctgtccc
     4021 ttcgatggat ttgagcacag cgtttcccgt gaaaccatct gccacaacaa catctgcaac
     4081 gccattcatc aaatcacgcg cttccacgtt tccgataaag ttcaaacttt catcagccgc
     4141 cagtaattca taagtttcct tacgaagcgg gtcgcccttg ctactctctg ttccgttgtt
     4201 gagcaaacca acgcgtggtt gcgcaatgcc acggacattt ttagcataga aggaacctag
     4261 aaccgcatat tgatggaggt gctgggctgt attttctgca ttggcaccaa ggtctagcat
     4321 gtcaaaacct tttccatcaa cggtaggcaa ggtagacatg agtccaggac ggtcgatatt
     4381 cttgatacga cccacgatga agaatcctgc tgccaacaag gcacctgtat tcccagccga
     4441 aaggacagcg tctgcttcac catctttgac agccttggct gccaatacca tactggcatt
     4501 tttcttattc cgaatagctc tcgtaggttc atcatccgaa tcaatcttct catccgtatg
     4561 gataatgctg acgcgctctg tcgctgtcag atattgcttg attttagctt catctccgta
     4621 aagttgaacc tcgatatctg aaaagtcaga tagggcttga ttgacaccct caacgatggc
     4681 ctgaggtgcg taatcgcccc ccatggcatc tactgcgatt tttttcattt cttttcctct
     4741 tttagtaatt gtccccagtc tgctagggaa tcaataaatt tctttgattt taggtgaatc
     4801 ccaacgtact cttcatatag ttgatccata aattggcgta gctcttgctt gattccaggc
     4861 ttgagcgaaa tggtctccaa agtctcaaaa tcaatagctt gaaattgatt gagcagatag
     4921 gggatattgg gattgagatg gcaacgtcta tcatcctcat gataatgctc tggacagaga
     4981 caggctccat atttgaaaga aaagtcaaaa gcctgaccaa cccgatggca gaagacacac
     5041 tcattaaaat tgaggctgat tccaaatcga gtcaaaattt gaatttcaaa aatattggtc
     5101 aaaacctgat aatccaagcc tgcttccatc aactccaaag tcttttgcaa aaaagcaaac
     5161 aagggagcat cctgctgatt gtcctgcaaa ctagcatctg caagagctgc cacataggtc
     5221 gcataggcca tgacaaagag gtcactatta atcttgggaa aagtcatgac ctcatgatag
     5281 tcttcgatgt aactgagtcc gtcatcattg attcgcaaga gaaatcgtgc cagcaccaag
     5341 ggctgaataa caggcgccag cttagactga ccagcgtgtt tgacaaaaaa catgcgtttg
     5401 ccaacctgct ctgtaaaaat tttgacgagc ttgtcatcct cacgaaaatt gcgattgtaa
     5461 agcaccaagc cttgactcgt gatagactga atcatgcttc tctcatgtac tcctcaagtc
     5521 gtttcatggc ttctttgata gtctccatgc tggctgcata agataggcgg acgtagcctt
     5581 ccccgtaacg tccaaaggct gcaccaggga taaaggcaac ggccttcttc tgagcaaaat
     5641 ccttcagaaa agcaaaggag tcttgattgt agcccgctgg aattttagca aaaatataga
     5701 aggcaccgtc tggtttgata atctcaaaac caagagcagt cattttttcg atgatatagt
     5761 cccgacgctg gatatattcc ttcttcatgg gctccgcatc gtttttacca gccgtcaagg
     5821 cttctactgc agcatgttgc gccatggtat ttgcggcagt gaccaagtac tggtgactct
     5881 tgattaactg ggctgtgaag gtcgcaggag cgaaaatcag ccccaaacgc caacctgtca
     5941 tggcatgcga tttagacaaa ccattgataa taatagcctg gtctctcaac atcgttccta
     6001 gagacacatg ggcttcgcct gtgtaggtca attctgagta aacctcatca cagacaacaa
     6061 aaatttcgta cttgcgtaaa acagctgcca aggcctctaa ctgctctcga ctgtaggtaa
     6121 ttcctgtcgg attggctgga tagttgagaa taaccgcctt gagcttatca ccctgctcca
     6181 aaatggcctt ctccaacatc tcaggagtca agacaaaacc attttcagtc gtatcaatct
     6241 caacaatttc tgccccaact aagttaacaa tcggttcata gcctggataa gcaggagctg
     6301 gcaaaagtac cttgtctccc tcttccaaaa tagccgtcaa agtcgcagat aaagcctctg
     6361 tcgccccaat tgtaaccaag atttcatttt caggagcata gtccagttgg tacttttcct
     6421 taacaaagtc actggctgcc tgacgtagag tcagcagacc actcatccct gtatagtagg
     6481 attggttctg atcaatcgct cgcttggccg cctccttgac atggtctggc gttgtaaaat
     6541 caggttcccc caaggtcaaa cgcaagaccc caggaatctc cgaaataacc tggtcaaact
     6601 gacgaatcaa cgaaacttga attttatcta actgtttatt aaagcgctta gttaagtcca
     6661 tagatacctc ctactttcaa aacgtatctc tattatacta caaaagcccc ccgaccgcaa
     6721 aaatacatta gagaatagct ttccactttc tattttactt ttcctgttta taggtctata
     6781 atggtaatag attttatttg gaggttttta tgtcatttct atcaaaaaat ggagcaggta
     6841 tcttggcctg ccttctcatt tccatcctat cttggtactt aggaggattc ttccctgtga
     6901 ttggcgcgcc cgtttttgcc attttcatag gcatgctcct acatcccttt ctctcgtcct
     6961 ataaacaact ggatgctggt ttgaccttta gttccaagaa gttgctccaa tatgccgttg
     7021 tcttgcttgg ttttggtctc aatatctcgc aggtcttcgc agttggccaa tcttcactcc
     7081 ctgtcatcct gtccactatc tcaatagctc tgattattgc ctacctcttc cagcgtttct
     7141 ttgcactgga tacaaaactg gctaccttgg ttggagtagg ttcttctatc tgtgggggtt
     7201 ctgccattgc agcgacagcg cctgttatcc atgctaagga aaaggaagta gcccaagcca
     7261 tttccgttat ctttttcttc aatgtcttgg ctgcgctcat ctttccaacc ctcggcacct
     7321 ggcttcatct atccaatgaa ggcttcgccc tctttgcagg gactgcggtc aacgacactt
     7381 cctctgtaac ggctgccgcc agcgcttggg acagtcttta ccaaagcaat accctcgagt
     7441 ctgcaaccat tgttaaactc acacgtactt tggccattat ccctatcacg ctctttctat
     7501 cctactggca aagtcgccaa caagaaaaca agcaaagcct acaactgaaa aaagtcttcc
     7561 cactttttat cctttacttt atccttgcct ctctcctcac tacactactc acctctctag
     7621 gtgtgtccag tagtttcttt acccctctca aacaactctc taaattcctt attgtcatgg
     7681 ccatgagtgc tatcggtctc aaaaccaatc tggtcgctat ggtcaaatcc agtggaaaat
     7741 ccattgttct tggagccatc tgctggattg ccatcatcct caccactctt ggtatgcaga
     7801 cccttatcgg cattttctaa cactcttcga aaatctcttc aaaccacgtc aacgtcgcct
     7861 tgccgtaggt atatgttact gacttcgtca gttctatcta caacctcaaa acggtgtttt
     7921 gagctgactt cgtcagttct atctacaacc tcaaaacggt gttttgagct gacttcgtca
     7981 gttctatcta caacctcaaa acggtgtttt gagcagcccg cggctagttt cctagtttgc
     8041 tagtgtgctc tttgattttc attgagtata acacaaaagg tagcccatca gctacctttt
     8101 tcttatgctt cctcaatcaa gcgagtatgt tctctcttga tacagcgatt catcacgata
     8161 tcatcacatc caccatcacg caaaatctct ttcgcttcta aactttcaag tcctagctgt
     8221 gcccaaaaaa tcttggcatc agctttgaga aaatcacgcg ccacatcggg cagaaattca
     8281 ctgcgacgat aaacattgac aatatctaca ggaaaaggaa tttcagcgag gctagcataa
     8341 gccttttcac ccaagatttc gccacctgcc gccttgggat tgactgggat gattttatag
     8401 ccccgagcct gcatttcctt tgttactcga ttgctggttg tttcttcacg gtcagacaaa
     8461 cccaccacag caagggtttt actcgttgcg agatactgac gaatcacgcc atcacttgga
     8521 ttgataaatt cttgactcat agaaatcctc ctttttcatc agtatagcac attttgaaaa
     8581 ggtttgcaga attatactac aaaaaaggag gactagcccc ctttttattt agcctcgtac
     8641 caggttgccc cttcattctc atctgcgata agaggaacac tgagttgaat ggcttcttcc
     8701 atggtttgtt tcaccaattt tttcatctct accaattcag atttaggcac ttcaaggacg
     8761 atttcatcgt gcacttgtaa cagcatctta gtctgataac cacctgcaac caaggcttta
     8821 tccagctgaa tcatggcaat cttgagaata tctgctgccg aaccctggat aggtgagttg
     8881 atagcagttc gctccgcaaa accacgaata ttgaagttgc gcgaattgat atctggcaac
     8941 tcacggcgac gcttaaagag ggtctctaca tagcccttat cacgcgcctc ccgcaccact
     9001 tcatccatgt agtttttaat atctggaaaa cgttcaaagt aggtatcaat gtaggctttg
     9061 gcttccttac gactaattcc caaattatta gacaagccaa agtctgaaat cccataaacc
     9121 actccaaagt taactgcctt ggcattgcga cggtcatttg cagtcacatt atcaggacgc
     9181 tcaatgccaa agacccgcat ggctgtcgaa gtatggatat ctgccccctc ttggaaggcc
     9241 ttaatcaagt gctcatcctt agaaatatgc gccaaaacgc gcaattcaat ctgtgaatag
     9301 tcagagctga gtagcacact atcctcccac tctggcacaa aagccttccg aatcaagcgc
     9361 ccttgttcca atcgggcagg aatattttgc aagtttggat ccacactaga caaacgcccg
     9421 gtctgggtca aatcctgcat atagcgagta tgaatctttc catcagccaa aatccagtcc
     9481 tgcaagccaa ttacataagt agattgaatc ttagcaattt gacggtaatc caggattttc
     9541 ttaacaatcg gagcaatagg agcgagacgc tccaacacat ccactgctgt cgaataacct
     9601 gtcttggttt tcttagtgta ttctagagga agtcccaatt tctcaaagag aagcacgccc
     9661 aactgcttag gcgagttgac attaaactcc tcaccagcca gctcgtaaat ctcttgagtc
     9721 agtttttcaa tgacaagctc attttcagcc tgcatctcaa gcaaggtctc tttcttgacc
     9781 acaatcccag caatttccat cttggcaaga acaaaagcca gaggttgctc catatcataa
     9841 agaagctcta attgcccatt ttcgctgagt ttttcaagta aaataggctc tgtttctacc
     9901 aaaacagcaa gtttacaagc taagtgttcc aagaatttct cacgttcagg aatggccttt
     9961 ttaacaccct taccgtagaa agtttcatca tcaaccaagt aagtctgacc ataaagacta
    10021 gcgatggtcg caatttcatt gtcctccaca gtcgaaagga ggtatttagc caaacggatg
    10081 tcaaaagcag gcgcctgcaa atccacacca aaacgttgca aaagaacttt aaccttctta
    10141 aagtcataaa ctctcagaga tgttttttct aagaaatcct tgaaaatcgg gtcttgcaac
    10201 agctcaagct tgtctgtggc atagagctta tcctcacaag accaggcaaa tccaaccaaa
    10261 ttatccgtat ggtaattctc accaaaaagc tcaaagtgga agatagactc ttcactcagc
    10321 atatcttgac tgatttggtc aacaatagta aaatccaaac ccttagccac atcagctgac
    10381 gacacattta aagcctgctt gagctgtttg aatcccatct catcgtaaaa tttcccaaga
    10441 ttttcaacat ctggaccact atagaccaag tcctctaaac caatcgcaat cggtgccttg
    10501 gtatcaatgg tcgctagtgt tttagacaaa aaggcctgtt ccttgtcatt gatgagattt
    10561 tccttcatct tagaagtctt cattccatca atattttcat aaatcccctc aagcgaacca
    10621 tactccagca agagcttaat acccgtcttt tcaccgactt tggtcacccc agggatatta
    10681 tccgacttat cacccatgag cgccttgaga tcgataaact gagctggtgt gaggcccatt
    10741 tcttccatga ggtaatctgg cgtaaaggcc tcaaactcag ccacaccttt cttggaaatt
    10801 tcaaccaccg tatgctcatc cgtcagctga atcaaatcct tgtccccact gacaatggta
    10861 atatcaaaac catcctgctc tgctagctta tccagcgtcc caatgatgtc atccgcctca
    10921 tactgagcca gctcatagtg acgaatcccc atatgatcca gcaactcacg aatgaaagga
    10981 aattgctcac gaaactcatc aggagtcttg gcccgaccac ccttatagtc cgcatacatc
    11041 tctgtccgga aggtcgtctt tcccgcatca aaagccacca aaatatgact cggctcaacc
    11101 cgctccaaca aatgactcaa catcaactga aaaccataaa tcgcattggt atgcaaacca
    11161 gccgcattct taaaacggtc caactgctga tacagcgcaa aaaacgcccg aaaagctaca
    11221 gaagacccat caatcaataa taattttttc ttatccatac acccattata aaggaaagaa
    11281 tcaaaaaata ccattgggaa gagctagagc aagtattttt caaacttttt ccgaataaat
    11341 agatagagcc agagaattta gtaaacctag atttaaaaat gtgctataat ataatatatt
    11401 gaatctataa tagtacacct tgactgctaa aatatttcta taaattaatt tgactttcct
    11461 gatagagtta ttcacatctt atttcaactc actatagaag gaggaatagg aggattctca
    11521 gacatccggg catcagccca actaatgatt tgattgctaa gaaaatattc agcaatccag
    11581 aaatcacttg tcaatttatt cgcgatatgc tggacttgcc agcaaaaaat gtgaccattt
    11641 tggagggaag cgatattcac gtattactct ccatgcctta ctcggtgcag gatttttata
    11701 ccagtataga cgtcttggcg gagttggata acggtactca agtaattatt gagattcaag
    11761 tccatcatca gaattttttc atcaatcact tgtggactta cctgtgcagt caggttaatc
    11821 aaaatcttga aaaaattcgt cagcgagaag gtgatactca ctagagctac aaacacatcg
    11881 ctcctgttta cgccattgct atcgtggata gtaattattt ctcagatgac ctggcttttc
    11941 atagctttag tatgcgcgaa gacacaacag gtgaggtatt ggcgattacc aacaatggac
    12001 aggaaaacca tctggttaag atggcattct tggaattaaa aaatacagag aaaccagcaa
    12061 agacaaggtt cgcaagccat ggttggagtt tttcggcaac aagcccttta cccagcaacc
    12121 gcaacgagcc attagccaag caaatcaact gctggactac aagagctggt ccgaggagga
    12181 caggaaaatg tttagtcaac tacatatgcg agaagaacaa gtcttgttag cacaggacta
    12241 tgccttggaa actgctaggg ctgaaggcct tgaacaagga ctagagcgtg ggaaagttga
    12301 aggaagggca gaaaggaaac tttttgcctt cctagacata gtacgccaag gtcttctgac
    12361 ttctgaggtt gccagccagc aattaggtat gtcagtatct gaatttgagg cactgttgta
    12421 aaatggctcc ataatatcca tagtgggtaa atcccctatg gatattatgg agcctatttt
    12481 gtgtagaaaa aaagtcccat atgacctata atgaaaagcg acaaaacaac tcattagaaa
    12541 gaatcatatg gaacaattac attttatcac aaaattacta gacattaaag accctaatgt
    12601 ccagatttta aacatcatca ataaggatac acacaaggaa atcatcgcca aactggacta
    12661 cgacgcccca tcttgccctg agtgcggaaa ccaattgaag aaatatgact ttcaaaaacc
    12721 ttctaaaatt ccttatcttg aaacgactgg tatacctact agaattctcc ttagaaagcg
    12781 tcgattcaag tgctatcact gttcaaaaat gatggtcgct gaaacttctg atgacgtata
    12841 gtcatatttc ttctcttttt attatatcac agttttaaat ctagctttac tagattcacc
    12901 gctactatcc atttattcgg aaaaaagacg aaaaaacctg agaatcatct caggcttggt
    12961 cattaaattt ttttctcaat atcgaaaagt ggagaaagtg gtcgtttttc atgaatacgt
    13021 acgatagcat cccctaggag atgagcgatt gaaatctgct caatcttatc aatcaaacgc
    13081 tcttctggca gatagatggt atccaaaaca accaatttct taatagctga tttttggata
    13141 ttgtccgtag caggaccaga aagaactggg tgcgtacagc ttgcatagac tgcaacagca
    13201 ccagcttccg caagagcatc tgccgcatga caaatcgttc cagcggtatc aatcatatca
    13261 tcaatcaaga tacaagtctt gccttcaacc ttaccgatga tgttcataac ttcactagta
    13321 ttcatcttat caacgctacg acgtttatca ataatagcga tagatgtttt caaaaattct
    13381 gccaacttac gagcacgagt cacccctcca tggtccgggc tgacaaccac atagtcagaa
    13441 ccaaccatac cacgccgctc aaaataatct gcaattagag gagcacccat caaatgatcc
    13501 acaggaatat caaagaatcc ttgaatttgc gcagcatgca agtcgatggt caataaacga
    13561 tccactccag ctacttcaag catatttgcg acaagttttg aagtgattgg ctcacgcgct
    13621 ctcgcctttc tatcctgacg tgcataccca tagtaaggca tgacaacatt gacagactct
    13681 gcactcgcac gcttcaaagc atctaccata atcaaaattt caagcagatt gtcatttaca
    13741 ggcgaactag ttgattgtaa gataaagacg tgtttcccac ggattgattc ttcaatgttg
    13801 acctgaatct ctccatctga aaattggcga acacttgatt tccccaactc tatcccaatc
    13861 tcctgcgcca cacgttctgc caattcttta ttagaagaaa gggcaaacag ctttaaatca
    13921 gaaaaagaca tgatttcctc cggtatatat gtatcgcttg tgcttttcac aagattttcc
    13981 atctaccatt gtagcgcttt ttgcactatt tttcaatcaa aaataaaaga agggcaccat
    14041 atttgtaccc ttgcatcatt cttttgaaaa atattctagg tcatcaactc attgtgtttc
    14101 tcaacaaagc aataagcatg ataataacca tagagagcaa tagccgtaac cactggaatc
    14161 gctaaaggca actctgtttc caactccaca aaaggagagt taaacaataa gaccctgttt
    14221 cttgccaacc ttctgtcctt tataggctct gtaaagcaag taaacaccta ctacagctag
    14281 acctgaaaaa gtccagtgag aggcaattcc tgagatgata cgctctaaaa ttcgcgaaat
    14341 agtaaagtca aagccctctg gcaaatccgt acgaatataa ccaatatcct caatcatttg
    14401 gaatcccaaa ccggaggcaa ttccaagtaa aaacaaaaat tttaattttc gcacaggaat
    14461 caaagccaaa acaaaaacaa gtggcaataa tttcaagggt tcttctacca aaggagccac
    14521 aatagcactt tcaaaggcat ttaaaaatgg actatctggg aaaagaaccc ccagtaaatc
    14581 atggatataa gtattagcaa aactagacaa ccagcctaaa aggaacatcc ctcccaataa
    14641 agacagaatc aaaaccttct ttggcaattc ccattttttc ccaatacgga agagaaaata
    14701 aagagccgga atcatgtaaa agagagctag aaagatagaa actcccatta gtccatattc
    14761 cgcacctgac ctcgaaccgt ccgtatagta gatggtttca tactgtaaac caatacatag
    14821 caataaaata aaaataaata aaatactgct tttcttcata cactttcttt ctaaatgaag
    14881 tatttataat tctacgactg ccatacttcc tgtatcaaca ttgtaaatgg caccagagat
    14941 aatgacatcg tctggtatta ggggagactc gataagcagt tgcatatcct cgcgtacact
    15001 ctcttctata tcttggaagg gcaagaagtc ctggtctgac acatcgacac ccaattcttc
    15061 cttcaaatac tcctgaaaag gttcattttc aaaggtctga gcaccacagt ctgtatgatg
    15121 caataccaca atttctcttg tccccatttg ttgctgggaa ataactagag aacgaatcat
    15181 atcctcagtc actcgaccac ctgcattccg caaaatatga gcatccccaa gtgccaaacc
    15241 tagagcttgc gcaacgtgca aacgtgagtc catacaggtc acaatggcta ctctggtttt
    15301 aggtttaagt ggcagattta actgcccatg tagggcaaca taagcctgat tggcttgcat
    15361 aaactgttca aaatacgaca cgattccctc cttgaaaatt tgatagtcaa atatttctcc
    15421 tatcttatca tttttaagag aatttgtcac ggattatgca aagacctttt tcaagacttc
    15481 ctgaatcgtt gtcacgccaa tgacctgaat ttccttaggc agagtgattc ctgtcaagga
    15541 attcttaggt acataaatct tagtaaagcc cagtttagca gcttcgttga tgcgttgctc
    15601 aatacgattc acgcgccgaa tctctcctgt caagcccagt tctccgacaa aacattcctg
    15661 aggattagtt ggcttgtctt tgtagctcga agcaatagca actgcaacag ccaagtcaat
    15721 cgcaggttca tccaatttaa caccaccagc agatttgaga taggcatcct gattttgcaa
    15781 gagaagccct gcccgttttt ccaaaacagc cataatcaag ctagcacggt taaaatcaag
    15841 tcctgtcgta gtacgcttgg catttccaaa catggtcggt gttaccaaag cctgaacctc
    15901 cgccaaaatc ggacgcgtcc cttccatggt tacaacgatg gaggaaccag tcgccccatc
    15961 caaacgctct tctaggaaaa cttgactcgg attgagtacc tcaaccaagc cgcccgactg
    16021 catctcaaaa atcccaatct cattagtgga accaaaacga tttttgaccg ctctcaaaat
    16081 acgaaaggtg tggtgacgct ccccttcaaa gtaaagcacc gtatccacca tatgctccaa
    16141 catacgaggc ccagccaagg ttccttcttt ggtcacatga cctacgataa agatggcaat
    16201 gttattggtc ttggccaact gcatgagttc agcggtcact tcacgtacct gagaaacaga
    16261 cccctgcacc cctgaaatct caggagacat gatggtctgg atggaatcaa taatgagaaa
    16321 gtctggctgg atacgctcca cttctgcacg aacactctgc atattggtct ctgcatagag
    16381 ataaaactca ctatcaatat cacctaagcg ctctgcacgt agtttaatct gctgggcaga
    16441 ctcctcccca ctgacataga gaactgtccc cacttgggac aactgggttg agacttgtag
    16501 gagaagagtt gatttcccaa tcccaggatc cccaccgatg aggacgagac ttcctggtac
    16561 cactccgcct ccaagcacac ggttgaattc ctccatctcc gtcttggttc gattgacatt
    16621 gatggaagtc acctcagcta gtttcatggg cttggttttc tcacctgtca aggacacacg
    16681 cgcattcttg acctcggcaa cctcaacctc ttccacaaaa gaagaccaag acccacagtt
    16741 ggggcaacgt cccagatatt taggggaatt atacccacaa ttttgacata caaatgtcgc
    16801 ttttttcttt gcgatgacaa acctctttct atatctctaa ctcacactca atcacttggc
    16861 aaaaatcaat cttctcattt ggcacaaact ggcgcatgag cattcgatga gcaacaacta
    16921 ccacagtctg atgttctcga tacttagaca tacattctag aaaccgagac ttcatttccg
    16981 tagctgtctc atattgaata ggactattag gaagcaactc ccccttgttt tctaaaaaca
    17041 gtcttctagc tgtttcaaag ttttctattc ctgttttata gacctgccat tcatgtaata
    17101 aaggctctac tcttaaagga agacccgtag cacagaccac atacgaagcc gtttctaaag
    17161 ctcttgtgac tgcagaagat acgattattt cagctgacga gagtaaagga tttttgctca
    17221 atttctggac ttgctgccgt cccatctcag acaagggtgc caaatctatc ccaaatccta
    17281 tataagaacg ctcctctaac tcacggtaat ctggctcccc atgacgtaca aagataatct
    17341 tcattctagt gccctgtcga tccaaatcca ccagttcgaa cgccatcagc tgcatctcca
    17401 tctgcaatta agaaagtagc aaaaacagcc tggacaatac gttccccaac ttcaagaaca
    17461 acctcttgat ctgtgatatt cttcatctgc gcaaaaatat gcccttcatt tccaggattt
    17521 ccataataat ccccatcaat gaccccaact gagttaatta aaaccaagcc cttcttacga
    17581 ggatttgaag aacgatcata gaggtagaga acctcagtcg gctgcatata agccttaacc
    17641 cctgtcggaa ccaagtcaat ctctcctggc gcaacaactg tacgcacagc aacctttaag
    17701 tcgtaaccag ccgcatgcgc tgtctcacgc ttgggcaata aattttcatc tgtaaaactc
    17761 gaaaccaatt caaaaccacg aattttcata attttctctt ttctattatc atttattcta
    17821 gattattcta tcttatttat tcggaaaaag cacgaaaaaa agagcacaca acaattatag
    17881 gcgatacgat aatttacact gtttcacaat acgttgaaat ttagagcttt aaagcgaggg
    17941 caaagttgat tttttacatc gttttacaga ggtttacgac acttttgccc cttttttgcc
    18001 cctttgtttt tcaaaaaaac ttcatcaaat cgcttgactt tcacggttta ccgtgatata
    18061 atataatcaa gataaggaaa ggaggtgagg aagttgaaca aagaagattg gcttaggtta
    18121 ctggaaaagg cgatagataa tatccctgaa acggtaactg ctatagcaag tctggtgact
    18181 gcaataacgg tcgcaaggca aaacaaaaag cgtaaaccga aatcccgtca aagaaaaagg
    18241 tgaacgctaa gaggttgggg cgaaagcccc tcacacctct attttatcaa atgaaaagag
    18301 gaaaagcaat ggttagtgca atagctattt ttataattgc ggtcaatgta tatatttatc
    18361 taaaaaataa aaaggacaaa taagatgaga gaagttattc aagaattgtt agacagttcg
    18421 atgtctacat ctgctatttc ccaaggtgct ggagttccat ggactactgt ttctgacctc
    18481 agaaaaggaa aaacaagcat ggacaaaatg gcacttctca cagcagaaaa actttatgaa
    18541 tttgctacaa ctgataagca gtgatttcgg tcactgtttt tatttttgac aaaacaccgt
    18601 ttttgacaat aatcaaaaaa taaaaaggag ctattattaa caaaatggcg tttttggcaa
    18661 taataccctg ccattcctcc tccctattct tcaagaaaac gcttttttga agaatcagag
    18721 caaataaaaa accgcaagcc tgagcctgcg gtgaaagaac aatttagaaa gtttcctttc
    18781 tatttattta actgtaatca agccatctgg ctctactgtg aactctggct tgtctgccag
    18841 tgttccgtct ggtttgaggt agtaccagcc tgttccgtcc gctgactgga taaaggcatt
    18901 tgataccatg gcgccttctt tagcgtctaa gtagtaccaa gtgtccttgt acttgaccca
    18961 gcctgtcttc atggcacctt ctacatcaaa atagtaccac ttgtcagcga ttttcttcca
    19021 gcctgtggcc atttcgcctg attggtcaaa gtagtaccaa ttaccgtctg tgtgcttctt
    19081 ccagcggtct gaaagcatat agcctgagcc atcgaaataa taccagatac cgttgatttt
    19141 ctcaaactta tagaaaggag gagatagtat ggcaaatact ccaataaaac ctggaacaga
    19201 taatcagaaa cctggtcgct atgtagaggt aggacctcgt ggcggaaaag ttactaatgg
    19261 tcataccgca actatcggaa aaggtgatcg gctccctccg acatctgcta aaggcaacgg
    19321 ttggaaaaaa gtctaatctt cgtttgcgta caatcgttca atggttgtac gctttttcca
    19381 tacacaaaag cacattccca aaaaatcaat ttgaatccat gcttcggcgt aatctttccc
    19441 attgctggca tagtgagtta tataatggtg aatcatttta ttccttcctc ctattgagtt
    19501 acttgagaag tatcatgaat ggcttcatag ctaagacgct taaattcttc tgagtctatc
    19561 tgaaaattga taggcttttt ttgtaaacac tcaagaaaac tagtgtttct taaaagtttt
    19621 tcaactaact cagggtctgc ctttacaaag gtggactctt tttgtccact atacggatat
    19681 cgttttggtc tcattttcct actcctcaaa tctttcctac tcaatcccat aatcttcaat
    19741 aacctgaaga atgaaactgt tcgctcgtgg acctttagtc gttccactta gaatgtttgt
    19801 cacttcctgt cgtttaaagc cgtaagcaac cgctagagtt gcttttttaa tgcctttctc
    19861 tttcaagaaa gcaataactc tttcgcgacc gtttgcgata tctggcatat tttctccttt
    19921 ctttttcttt cttctttttc tgctataata taagcagaaa ggagttaacc ttatgacttt
    19981 taaagaatat ttactcaaag caagcaaacg cgacatctac gatgatggta aagattttga
    20041 gaaatcaatt tcagattctc actaatcgag cgtgactttt ttgatatggc aatctcagaa
    20101 atttaccacc agcgctgact accttaatga ctttttcaag gtggtctttt tcttgttcta
    20161 aatttttaag aatacttacc atcagcacgt tcctcctctt tacttatttg taaataagaa
    20221 acaactaaaa atgtaactat ttttctgcat tatacttgac aacttacacc aaatcggcta
    20281 aaattaaagc ataataaaaa caccaataaa tctataaata ccgttcgcca aaacattttt
    20341 ataatttatt tcttagttgt ttttttagtt gtttatcact tacaaaaaac attttacacc
    20401 tttttggata attagtcaac ctttttacac caaatttgtt aaaatttttt tgtgatgtct
    20461 tagaaaggtt gatttaacaa tgtttgagac atttgaaaaa ataaaagaat tggcaaaaaa
    20521 gcgtggaaaa gctcttggac aagtagaaga agacttaggt tatggtagaa atacactcta
    20581 taagataaaa aattctacgc caaacgctga acgtatcgca gaaattgcta attatttcaa
    20641 cgtatccacc gactacctgc tcggacgaac agataaccct gctatcgctg ggagtgatga
    20701 atttgcccaa gtaaacggac aaatcataga cttacgcaaa gcagcagcca acaccatgtt
    20761 atttgacggg aaaccactaa atgaagatga tatcgacttc attacatccg tcctatccgc
    20821 ccacttcaaa agcaaaggag aacgctaatg actatcacta tcaacttcac agaaaaaaat
    20881 tcctacatta cggactacct aaacaaacac ggtatcgaca caacgaccat ggattttgac
    20941 gacttcatgg cactcatgga agatatcgaa gacgcacgag cagccgacca agcctatatg
    21001 gagtatttag ccgacccagc tacttatacc atggatgagg tcttggatga actaggacta
    21061 actcgagagg atattgctta atgtatcggc tagatattga taaaaaagct ctcaagcaac
    21121 ttaaaaaact agatacccca accagaaaac aaatcctatc ctggcttgct aaaaacattg
    21181 aaaacacgac caatccacga caacacggaa aagcactaaa agccaacctt gcaggttact
    21241 ggcgatacag agtagagaat taccgcatca tctgtgatat ccaagacgat aaactagtcg
    21301 tcctagccgt ggaaatcgcc caccgcagag atgtctataa ataacgaagg agaactatga
    21361 cactcgctaa actctgcgaa gaatatcaag tagaactttg tctcttcgac ggttcaaact
    21421 ggcacaatag cggtttctac aatccagaca caaacgtgct cgctattgac cacaacttga
    21481 ctcctgaaca acaaatccaa gtcgccctac acgaacttgg acacaaagac cacacacgct
    21541 cagagcacca gaacgcccgt ctacgctgtg aaaacgaagc tgatatatga tccatcatct
    21601 cgtaaaagac gctctagaaa acttagacga ccccacagag tttgattacc tcaaattcat
    21661 gtcttactac aatctaaaaa ccatgacaaa tgaaatcatg gttaaagaag agtatttagc
    21721 attagtaaat taaaaaaagg agtatcaata tggaaattga taaagtaaaa gccgatttaa
    21781 aacaagtcgg caaacgtgta gcagacctca gccaaagcat tacgaatgaa gaacaaacaa
    21841 agaatgcctt cattatgccg ttcttccaag cgcttggata tgatatcttc aatccacttg
    21901 aatttgtccc ggaatttact gccgacgtgg gcattaaaaa aggcgaaaaa gtcgactatg
    21961 cgatcatttt ggatggcgag cctcaaatcc taattgaatg taaatcaatt acagaaaacc
    22021 ttactaagca cgactctcaa ctattcagat atttcgtaac tactaaatca aaattcggta
    22081 tcttgacaaa tggtagagaa tataaattct ttactgattt agatgagcca aataaaatgg
    22141 acacaactcc attcttaaca atcgatgtga ctgatatcaa agaaaatcaa tttactgaaa
    22201 tcatcaaatt ccacaaagag aattttgata ttgataatat tgtttcatca gcttctgaat
    22261 tgaaatacct caacaatctt aaagcgttcc ttactgaaaa tatcactaca ccgtcagata
    22321 gcttcctcag atatctaact tctgaaatct atgaagggcg tgttactcaa aatatcttaa
    22381 cgacattttc tcccattatt gtgaaagggt ttaatcaatt catcacagag cgagttaatg
    22441 aaaaattaag tgctgcactt aatacaagcg ttgaaaccaa agtaacaacc gatattccaa
    22501 aagttgaagc tgaagctgaa gagattgtcg aagtaactga cgaaattatc acaactcctg
    22561 ctgaattaga agtttatact gttgttaaaa tgcttgctag ggatgtagtt tctccagaac
    22621 gtgtatttta cagagataac cgtagctatt tcaatgtttt ggttgacgat aacatcaaaa
    22681 aatgggtatt acgttatcgt tcaaattcaa aaaaaagcac tatcgaaatc cgtgataaag
    22741 gcatcttccc ggtgtctacc cctctcgaag tcgcaaatta tgccaatgaa attttagaag
    22801 taatcaagaa attctcataa taaaaaaagc cctctttact atacccattt tatcaaaaaa
    22861 gtgaggtaaa atcaatgtgg atggaagaat tgccaaacgg caaatataaa ttttttgaga
    22921 gatacaaaga tccatatact gagaaattaa aaaaagtctc agtaacgatg gagaaaaaaa
    22981 ctccccaagc aagaaatcaa gctgcgattt tacttcagga aaagataaaa caaaagttag
    23041 gagaaaaaca acattctgtt tctaatataa cttttgaaaa actatatgaa gaatttgagg
    23101 agaattggaa acacggcgta aaaaactcaa ccgtctacgc ttcaaagaat gtaaaaaaag
    23161 agattttaaa gcagatagag ggcgactacc tagttagaaa tttgatagac gtttattaca
    23221 aaaagtaata gatcaactat tacaagatgg gagatctcat aactatgttt ctaaaatcaa
    23281 attcaagctc aatcagataa tgaaatttgc tatcagaatg aattatattg atacaaatga
    23341 aatgctattt gttgaaacgc ctagaaaagt aattacatcc gacgaactca gaaagaaaaa
    23401 tacaaaatac ttagaccaaa aagagtttaa gttattcatc caaaatttaa aagacgaggc
    23461 cctatgtgat tatcgaatta caaagtatat ccgaatagct aaagttcttt ttcttactgg
    23521 catgaggtat ggagagctgg cagccttaaa ctacaaggaa gatatagatt tttctaaaaa
    23581 gactattcac atcaagcata catacgattt cagacaaaaa gagagaacta caccaaagac
    23641 aatcaagtcc gatagggtta taacagcacc tcaaaaagtg ttagatatta tcaaagagca
    23701 aataatagag aatgcgacaa atggatttga tacagatttt attttcatca atactctagg
    23761 agaaccaata acaaatgcca gggttatttg tgcattgaaa agacatggtc aaaaaatcgg
    23821 catagaaaaa aacataacta cacatacatt tagacattct cacatatccc tacttgctga
    23881 gctgggcatt cccttgactg ccatcatgga cagagtaggg catagtgact caaagaccac
    23941 actagagatt tattctcacg ttactcaaaa aatggtatca gacatatcta gcaagttaga
    24001 caagataaaa ttttaaattg tgcccctcgt ctgccccttt ttcttataca agacaaacaa
    24061 aaacccctta aagtgttgat tttaaagggt ttttaaagtg cacgaaaaaa gagcacacaa
    24121 ttcaaatcgc ttagggctgc tggattcctc ccctgacccg cttcacgcag aactgttgct
    24181 ccactattta ttatatcaca ttcctattca ttttaaaagc aaaattattt tttccgtcta
    24241 tttctaaaaa aatcctgcat gatagctgcg cattcatctt ccaaaattcc tatttcaacc
    24301 tccacacgat gattgagacg ctcatctgtc aagatatcgt acaaactccc agcagcgcca
    24361 aatttctggt ttttagcccc atagaccaca tttggaatgc gggcaagccc aatcgcccca
    24421 ctacacatga cacaaggttc aatggtcaca aaaagtgtgc aatccagcaa gcgccagctc
    24481 tcctcactca agttcgcatc ctctatagcc ataatttccg catgcataac cgctcgctgt
    24541 aattcctcac gcgcattatg cccacgacca atgatttccc catctttgac aatcacacaa
    24601 ccaattggaa tttcatcgtg ttcaagagca atctcagcct ctctcaaagc ctccctcata
    24661 aagacttctt tttcttcaag cgtataatac atctcttttc tcttttccta cttatcgatt
    24721 ttattattat atcatgaatc ccaacacaaa agaagccacc gaatgcggtg actctatagg
    24781 gagattatta tgaaaaagaa aagtttagga tatttgttac aacaagttag gaggtcttct
    24841 tgtaactgtc tatagtatac ccgacctatc ttaaacaaat cttaaaaatc tcttaggacc
    24901 aaacactttc taaaatattt gtttgttcac gaccaggacc tactgagaaa gtagaaatac
    24961 gaacgccaac caattcactc acacgacgaa catagttacg cgcattctca ggaagatctt
    25021 ccaaattgcg aactccggta atatcttctg accaacctgg caactcttca tagataggct
    25081 tgcaacgttt caattgctca agactagctg gatagtagtc aatacgttga ccgtcaagat
    25141 cataggccac acagattttc acagtatcca aaccgctcaa aacatcaata gagttcaaag
    25201 aaaggttagt aataccagaa acacgacggc tatgacgcat cacaactgag tcaaaccaac
    25261 ctacacgacg tggacgacca gttgttgtac catactcatg acccacttca cggatacgtt
    25321 ctcccacttc atcaaacaac tcagttggga aaggaccatc tcctacacga ctcgtataag
    25381 ctttacatac acctacaacc ttgtcaatct tgcttggacc gacaccagaa ccaattgtca
    25441 caccaccagc tacagggttt gatgacgtaa caaatggata agtaccttgg tcgatatcta
    25501 gcataacacc ttgtgcacct tcaaaaagca cacgtttgcc attatcaagc gcatcattca
    25561 agataacaga tgtatctatc acgtatttct tgatttgttg accatattcg taatattctt
    25621 caaaaatatc atcgaaaaca atcgctttac tgtcatacaa tttttcaaaa agacgattct
    25681 tttcagcaag gttacgttct aaacgctcac ggaaaatatc tttatctaaa agatctgcaa
    25741 tacgaattcc aacacgagca gccttgtcca tataagctgg accaattccc ttaattgtcg
    25801 taccaatctt attgtcgccc ttagcttctt cttgcaagcg atccaactcg atatgataag
    25861 gcaaaataac atgcgcacga tcagaaatac gcaagttatc agttgttaca ccttcctcat
    25921 gaagatagct caactctttt acaagagatt taggatttac aaccatacca ttcccaatga
    25981 cagatatttt ttcagggaag aaaatcccag atggaatcaa gtgcaactta aatttcttac
    26041 cgtcaatcac aatcgtgtga ccagcattat caccaccttg gtaacgtgca atcacttctg
    26101 cattcgctga aaggaagtct gtaatcttcc ctttaccttc atcaccccat tgggtaccta
    26161 caacaacaac tgaagtcata attttgtctg agccctcagg ctcttccttt ctcacataca
    26221 tggcaggact ctcacctgca attatatctt acaatttatt ataataaaaa atcgcctttt
    26281 tatcaagaag aaacaataga aagatttgct atttccaact attaaaaaat gatttagaaa
    26341 aattactagc tatttactat tatctttaca taaaagagta aattagttcg gaaatttact
    26401 aaaattacct caacaagaaa taaaaccccg attcattacc aatttttcaa gatacaaacg
    26461 ataagcaaca cgataatggt aaacgataaa atccctatga caaccaatgc catatctcac
    26521 taaataataa attaaaaatt taaaatgaac atgttcccag tcaaaattat caccaaatgt
    26581 aggaccatac tcttcttcaa tactatcata gaaattagcc atctgctcat aaattttttg
    26641 taacataatc aaatactcct tttctttttt ataaacttat tctaacaaaa aattttacac
    26701 attcactatc aattcctgaa ttgttaaaat accagcctca acaagataaa aataggaaaa
    26761 gttgacaaaa tagaaacaaa tttgctacct aaatttcaaa caattaaagt tctaaaaaga
    26821 ccgccttaaa acttttgggt aaatcctatt agaactataa tatttttata taggtattat
    26881 ggttctgatt ttctagtata aaaaaattca aactagaatt cttcttagaa aaggccgttt
    26941 taagtgctat cattgctcaa aaatggagct cgctgagact tctatcgtca agaagaatca
    27001 tcaaattcct tgtatcatca accaaaagat tgctcaaaag ttaattgaaa agatttctat
    27061 gaccgacatt gatcatcagt tgtctatttc aacttcaact gtcattcgca agatcaataa
    27121 ttttcacttt gagcatgatt tttcgcgtct tcctgagatt atgtcctagg acgttgaaac
    27181 agtccgggga gtgactgttt caatcgggag atggagatga gctttattgc tcaggacttt
    27241 gataaactca atatcataac tgttcttgag agcagaacac aagccatcat ccgaaatccc
    27301 atgaatacaa ggctatcaag cgctactgga agctcattca acaagatagt cagaaactga
    27361 gtgataaacg attttatcgc cctacttttc gtatgcactt gactaataaa gaaattctag
    27421 ataaactttt gagctattcc gaagacttga aacaccacta taatctctat cagctcttgc
    27481 ttttccacct ctgtttcaga ctttgtttaa aaccttcctc aaagataaag agaaaatcgt
    27541 caacgccctt caattacctt attccaacgc caaactggaa gccaccaata atctcatcaa
    27601 acttatcaag cacaatgcct ttggttttag gaactttgaa aacttcaaaa aagaaaggac
    27661 gaaatttgtc ctttctagat cttcgctttc ttcaacccac tacagttgac aaagaaccga
    27721 aaaatgtctc gcctctaata tagtcaattg aaacaagaac aagagaaaag agcctcgtaa
    27781 aaggtattgc aacttggtaa tacctttttg aggttctttt tgatataagc ccatgttttc
    27841 tcaataggat tgtactcagg tgagtaggga ggaagaggta aaagtttatg cccaaactcc
    27901 tcgcataaaa gttctaactt acccattcta tggaatcttg cattatccat aataataacc
    27961 gatggtgtgg ttaatgttgg taagagaaac ttctgaaacc aagcttcaaa aaagtcgctc
    28021 gtcaccatct cttcgtaagt cattggagcg attaactcac catttgttag acctgcaacc
    28081 aaagaaatcc tctgatatct tcttccagat actttacctc ttattaactg accttttaat
    28141 gagcgaccat attctcgata aaaataagta tcgaatcctg tttcatcaat ctaaacaggt
    28201 gctaggtgct ttaaactatt aaaattttta agaaataagg ctactttttc tgggtcttgt
    28261 tcatagtagg tgtggttctt tttttcgagt gtagcccata gctttgagcg catagtggat
    28321 ggtagttgga tgacaggcaa attcagaagc tatttcagtc aaataagcgt ctggattgtc
    28381 agtaagatag tttttaagtc tatctctatc aacctttctt ggttttgttc cttttacttg
    28441 gtggtttagc tctcctgttt tctcttttag ctttaaccag ccataaatgg tattac
//
LOCUS       DAVLCS010000027        25332 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLCS010000027 DAVLCS010000000
VERSION     DAVLCS010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25332
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.027"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(248..466)
                     /locus_tag="VXC78_001352"
     CDS             complement(248..466)
                     /locus_tag="VXC78_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0583420.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(712..990)
                     /locus_tag="VXC78_001353"
     CDS             complement(712..990)
                     /locus_tag="VXC78_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583421.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1204..2835)
                     /gene="rlmD"
                     /locus_tag="VXC78_001354"
     CDS             complement(1204..2835)
                     /gene="rlmD"
                     /locus_tag="VXC78_001354"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0583422.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGLAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2909..3883)
                     /locus_tag="VXC78_001355"
     CDS             complement(2909..3883)
                     /locus_tag="VXC78_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV0583423.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDSDKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3957..4571)
                     /gene="pmp23"
                     /locus_tag="VXC78_001356"
     CDS             complement(3957..4571)
                     /gene="pmp23"
                     /locus_tag="VXC78_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV0583424.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLTLAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4571..5545)
                     /locus_tag="VXC78_001357"
     CDS             complement(4571..5545)
                     /locus_tag="VXC78_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV0583425.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5553..6809)
                     /locus_tag="VXC78_001358"
     CDS             complement(5553..6809)
                     /locus_tag="VXC78_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV0583426.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6871..7302)
                     /locus_tag="VXC78_001359"
     CDS             complement(6871..7302)
                     /locus_tag="VXC78_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0583427.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7304..7906)
                     /locus_tag="VXC78_001360"
     CDS             complement(7304..7906)
                     /locus_tag="VXC78_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV0583428.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7890..8729)
                     /gene="prmC"
                     /locus_tag="VXC78_001361"
     CDS             complement(7890..8729)
                     /gene="prmC"
                     /locus_tag="VXC78_001361"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV0583429.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8729..9808)
                     /gene="prfA"
                     /locus_tag="VXC78_001362"
     CDS             complement(8729..9808)
                     /gene="prfA"
                     /locus_tag="VXC78_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV0583430.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9805..10395)
                     /locus_tag="VXC78_001363"
     CDS             complement(9805..10395)
                     /locus_tag="VXC78_001363"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV0583431.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10518..10700
                     /locus_tag="VXC78_001364"
     CDS             10518..10700
                     /locus_tag="VXC78_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV0583432.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10836..12209
                     /gene="mnmE"
                     /locus_tag="VXC78_001365"
     CDS             10836..12209
                     /gene="mnmE"
                     /locus_tag="VXC78_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV0583433.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIVQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEQLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12256..13191)
                     /gene="dapA"
                     /locus_tag="VXC78_001366"
     CDS             complement(12256..13191)
                     /gene="dapA"
                     /locus_tag="VXC78_001366"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV0583434.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13247..14323)
                     /locus_tag="VXC78_001367"
     CDS             complement(13247..14323)
                     /locus_tag="VXC78_001367"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV0583435.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14909..14981)
                     /locus_tag="VXC78_001368"
     tRNA            complement(14909..14981)
                     /locus_tag="VXC78_001368"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14946..14948),aa:Thr,seq:ggt)
     gene            complement(15081..15590)
                     /locus_tag="VXC78_001369"
     CDS             complement(15081..15590)
                     /locus_tag="VXC78_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV0583436.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15588..15684)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15713..16144
                     /locus_tag="VXC78_001370"
     CDS             15713..16144
                     /locus_tag="VXC78_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV0583437.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            16226..16603
                     /gene="mscL"
                     /locus_tag="VXC78_001371"
     CDS             16226..16603
                     /gene="mscL"
                     /locus_tag="VXC78_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV0583438.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16645..17739)
                     /gene="hemH"
                     /locus_tag="VXC78_001372"
     CDS             complement(16645..17739)
                     /gene="hemH"
                     /locus_tag="VXC78_001372"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV0583439.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVTLVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            17894..19114
                     /gene="pepT"
                     /locus_tag="VXC78_001373"
     CDS             17894..19114
                     /gene="pepT"
                     /locus_tag="VXC78_001373"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV0583440.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVRSL"
     gene            complement(19157..19786)
                     /locus_tag="VXC78_001374"
     CDS             complement(19157..19786)
                     /locus_tag="VXC78_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583441.1"
                     /translation="MSKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVAA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTTGNQEKPVE"
     gene            19751..19972
                     /locus_tag="VXC78_001375"
     CDS             19751..19972
                     /locus_tag="VXC78_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583442.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVFLKQESYNPRLQ
                     GLTEIRNPDKTMSVQDAIRFAQQRGFNML"
     gene            complement(20049..20696)
                     /locus_tag="VXC78_001376"
                     /pseudo
     CDS             complement(20049..20696)
                     /locus_tag="VXC78_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521835.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(20800..21360)
                     /locus_tag="VXC78_001377"
                     /pseudo
     CDS             complement(20800..21360)
                     /locus_tag="VXC78_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(21586..24705)
                     /gene="phtE"
                     /locus_tag="VXC78_001378"
     CDS             complement(21586..24705)
                     /gene="phtE"
                     /locus_tag="VXC78_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV0583443.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLVGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     SEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSETGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(24915..>25332)
                     /locus_tag="VXC78_001379"
     CDS             complement(24915..>25332)
                     /locus_tag="VXC78_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV0583444.1"
                     /translation="KNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDETEIPQVENSVINAKIAEAEALLEKVTDSSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
BASE COUNT         7232 a         5231 c         4610 g         8259 t
ORIGIN      
        1 aactcatcaa taaaaatttg tttgctaata tctctttctt ctgattttgt ttcaaggatt
       61 attgctacat cattcatatt tttaggtaaa taccaaccat ctggcttatc tgaatatccc
      121 ttgaagccta attgattaaa agtagttatt tgaccagtac cttgattgat gttttcttca
      181 acttcattaa agcctatact tctcttgcat aatccctaac ttgatcttct gtccttaaag
      241 tcattttcta ttcctcgtca ctaaaattat cttcaaaact aataatatca ttaggagtgc
      301 aagataaagc cttacatatt ctttctaaat tcttaaatgt aattggttta tcctttccca
      361 tttgtgccat aacatttgtt gtaagtcctg ccatagctat tacatctgtt ttctttagtc
      421 ctttttttgc taactgtatc cataatggtt tatagttaag tgccataata tccctctttt
      481 tttcttcatt aaatttattt aattatagca taaatattga tttcattcaa tcttacattg
      541 atttagtgat ttgttttaga gaatttgttg tgttattccg tccttatttt gccataaatt
      601 gttttaagtg ggacctctta tccttaccat ttttacctcc taattttgag tataaaaaag
      661 acgatagagt ttttaatttc tatcgtctga gatttacata ttaaattttc atcacaaaat
      721 aagactcttt aaagaatctt taaattcatt ggtatgctgc ttacaatatc cattattaaa
      781 atggatattg taagcagcac accaactatt tattttttga gttttaaact ttggtagaag
      841 tcttgaactc cttatattta cataactatt tgcctctata actgttatga cacgaaacca
      901 acaagcaagt tcaagcacct ccatatcttt attcaaatga ggactaagat attcacaaac
      961 tttatcataa acctctttat cttttttcat aaaaggggca tacaacttag caaatttatc
     1021 ctaaaatttt ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat aaaaatgatc
     1081 ctatcaatct ttatattgag cctattttct aattgatacc ttgcaagaaa ggaataatag
     1141 ctgttcctat accaagtagg aatgtaataa atgcagaaag tcatatactg tcattctttt
     1201 ctattaaatc attttgaagt gtctcaaagc atccatgatg gcttcttctt tttcaggtgt
     1261 acactgtgga ataatttgtt tatccttttt agacttgttg taatgttctc gtaattctat
     1321 tccacatttc ttttttatct gtgcaatata taatgtcgaa acttttaatt caaatttatt
     1381 ccaaacatat tctttgattt gagcatatgt tgctttgctc tccgcacttg tcaaatccat
     1441 ctcatccagc tcaatttcaa cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc
     1501 taccgtctcg acgtgatgcg tttgaggaaa tagatccacc ggctggactt tcttcaattc
     1561 atatcccaac tcttggtata gtttaatatc acgcgccatg gttgcgacat tgcaggagat
     1621 ataggcgatg cgatcggctc ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc
     1681 cttgcgtgga ggatcaacca agataacggt tggttgaatc ccatctttaa gccaattctt
     1741 catagcattt tcagctgtgt cacagacata gtgggcgttt gaaatattgt tcagctgagc
     1801 atttttttta ctattctcaa ccgcttctgg aatcagttca acaccgtaga cttctttgac
     1861 atgcttggcg actgataaac caatggttcc aataccagaa taagcatcaa taaccacgtc
     1921 atcttttttt aactctgcaa agtcaatggc tgtttgatag agtttctccg ccatttcagt
     1981 attgacttgg taaaaggcta ggccagcgat ttggaagtca tttcccaaca tctggtccgt
     2041 aatatagtct tgaccataaa gagtgcgcca ctccttacca aaaatcgcat tggtattctg
     2101 gtcgttgata ttttgcatga cagacacaat ctctgggaac tgcttgataa cttgttcaat
     2161 caattggtca acacgaaaaa cttttggacg agttgtcacc aaaacgacca tgatttgtcc
     2221 tgaatagtga ccacgacgca ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc
     2281 ataaggtttt aaatcaaaac gacggagcag gtctcgaaga gctactacga cttggtcaat
     2341 gacaggatcc tggataaaga aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa
     2401 aaatcctgtt tccaagacac cattcactcg acgaacgggc acctgcgcct tattgcgata
     2461 cttgactgga tgttccatac caagcgtttc agcaacttct acatctgcaa ttccagcaat
     2521 cttgtagaga ctgtccttga cttgcttggt tttaaacttg agctgttctg gataagaaag
     2581 gtgtcctaaa tccgcgattc ctgaacgcag gtaagccaaa tctagatctt gattacggtg
     2641 tggtgactgg acaaggtatt tttcaacttt tccaaagcca atctttttat tgaccttgag
     2701 gacacgcatg agaatttttt cactcggtaa agcattctct acaaaaaaga ccaaaccatc
     2761 taccttggca actcctgccc cttcatgggt caaatcaaca atttcaactt ctacaatatc
     2821 atttttcttt aacattcttt tctctttcta ttggccgaca aaaaagacgg caacgttacg
     2881 gttaccatcc attataccat gaaatttctt aagaaccaaa actcttgaag aagttgacaa
     2941 gggcttgcca gagggagctt aagaagttac caccgtcctc tagcgcctta tccgaatcaa
     3001 agttaaggtt gatattttta aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt
     3061 catttaaggt tttagtgaaa tctgcattgc tgaggatatc actctttgag agattcaagg
     3121 caaaattgat gatgatattg atctggtttc ctgttatgac ctgatcaagt ttgtaatttt
     3181 ttaaggtatc ttcaacaatc ttgcggatat cttcttctgt cagatttccc ttgctttctt
     3241 tagctttggc gagtcctgac ttgatatcag ctagggcaac gtttaattta ttagcatcat
     3301 agcctgattt gtccttgttt tcagcattga tatctgacaa agcctttagc tcttcttgag
     3361 ccaaatcttt attggcttgc ggcaccttgg ctccattagc ttctagcgaa tagtagatcc
     3421 cagccaaagc actctcacct gtaactggaa tgggtgctgc tacagtgatt ttggcgtgtt
     3481 ccacacccaa agttacggct gcatttcggt acatatcctg agttacctta gtgatgtttt
     3541 caggtgtttc aatcttgacc tcaagtggcg atttgtcacc tagcttttga atcttggctg
     3601 atgaatacaa ctgtaagcta gagtcattgg ccacattcat gattttagaa taaacatcag
     3661 gtgtcatggt cttgagttct ttggtatctg ttgaggcatt gtagcccagt tttttaagag
     3721 tttgattttt ttggtcttca gatagggaag aacctaggac atattcaggt tggacatagg
     3781 tttcatcgat aactttttga acatctgttg ctgcatggac gctattcata gctgttactg
     3841 cccacaagat cgcagcgcta gtcagaaaga gtttctttct catagggaat ttcctccttt
     3901 acttctttag agtaatatat ctatcttaaa gaaaacttat aacaaaaaca cctggtctag
     3961 ccagatgttg aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta
     4021 gaataataat agtttcctcc atttacatag agttcagcac cgtgaaaaat ggaaatgggg
     4081 tgaatataac tataagtctt tccagtccta ttaccaagca agggggcaac agtctcacga
     4141 gagtactgtt tggctagagt caaggtattt tccttgccat tttgggcgat aaaatcgata
     4201 taggcaggtc caaaattata ggcttgaaca gctgtccaga tatctacacc cttcttctgc
     4261 gccagataga gattgcctgt cagagtttga atgccttgcc gaatgctaga ggcattatca
     4321 ttgatggtgt tggtggaacc acttgcagac tcactagact gcataacatc gccttctttt
     4381 ccttttgttt cagtataaat catagcaagc acaagctctt cgtttgctgg ggtgtctttt
     4441 tcactcaata tttctcgcac catgggttga taggtcatga cttgtttgac atcttgatga
     4501 acgcggtaag ctttatagcc agcaaaaagg aagactgcta gtacaagcac tcttcgaatt
     4561 cgtttaaaca ttatttactt tggatatcct cgatattttt gattaagata gagtaggttc
     4621 cattttcgtt ttggataaac tcaacagact cggcgtcttg atagacgtta ttgggaacga
     4681 tgagctcaat tccatttgat aaggagagtt tttggttttc aaatttcttt aattggcgac
     4741 tggcatcaat ttcatcaaat tgaacaggtt ctggtacggc ttctttgact tggtcaataa
     4801 agctcaaacg agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca
     4861 attcattgct ttcttctagg ttgttgaaaa tagctgattt gaccttggat tgaaattgaa
     4921 aatcatctgt gttaaaagat tcagcaattc tctgggctgt tttttccagt tccttgatag
     4981 attttttagg agaaatctta ggagcgacag caagaagatt atctgaaaaa tagttcaaaa
     5041 aagtcccgtt gtacttgatt cgtttttcaa tcaggtgata cttgcgactc tgaagattga
     5101 ccaccaaggc ctcgtcagca cccgttccaa atccaggcag gttattctga gtcagcttga
     5161 ttggattatc aacttctcct ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga
     5221 aagcgaaatg ttctacacct tctttagaaa attgaacaaa aatcaagtca ttggtcttga
     5281 gattttcaga aatgctaaac tcctctttcc agagattagc cagcgttact gatgtctcca
     5341 acaaatcgtc tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg
     5401 cttcatctga atacacatgt tcaatttttt tacgtaggta ttcttcgatt tttggagtaa
     5461 tattgagaaa cttatctgct aagaacagct cggtatcatc cggactgaac tggtgaataa
     5521 tggctttctt aatataaatg tccataaaag ttttattcct cgtataatgg gaaggcatct
     5581 gtcaattctt tgactgcact tctcacttct tctaatacag cctcattttc tgaattctta
     5641 agggttttaa tgatgagttc agccactttg cgactttctt cttcaccaaa tccacgtgca
     5701 gtaatagctg ctgctccgat acgaatccca cttgtcttga atggtgacaa ggtttcgtaa
     5761 gggattgaat ttttatttag ggtaatattg acttcatcca gcaagttttg agcaactttt
     5821 ccgttttcta caaccttagt cacatcaaca aggaagagat ggttttcagt tccacctgaa
     5881 ataatacgga aatcagggtc ttgcaagaag acatctgcca tagccttgct gttcttaatt
     5941 acattggcag catattcctt gaaggctgga tccaaaactt ctttgaagga aactgcctta
     6001 gccgccacaa catgctctaa aggaccgccc tgaatacctg ggaaaatagc tgaattgatt
     6061 tttttagcaa gttcttcgtc attggtcaaa atcaaaccac cacgaggtcc acgaagggtt
     6121 ttgtgggtcg ttgttgttgt gatatgagcg tatggaactg ggcttggatg aaggccagcc
     6181 gcaaccaaac cagcgatatg ggccatgtcc accatgagct tcgcaccgac agcatctgcg
     6241 atttcacgga attttgaaaa atcgataatt tgagaatatg ctgaagcacc agctacaatc
     6301 agttttggtt ttacttcttg ggcttgtttc aagatagcat caaagtctaa gagttccgtt
     6361 tcaggatcaa cactataaga aacaaagttg taggtttgac cagagaagct aacaggagcc
     6421 ccatgagtca aatgaccacc tgatgccaaa tccattccca taaccgtatc acctggctca
     6481 atcaaggaca tgtaagccgc acagttagct tggcttcctg aatgtggttg gacattggca
     6541 aatttagcac cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac aacgtctact
     6601 acatcagttc caccataata acggcgtcct gggtaaccct cggcatattt atttgtcaag
     6661 atagaccctt gagctgccat aacagccttg gaaactacgt tttccgaagc aattaactcg
     6721 atattatttt gttggcgttc ttcttctttg gcaatagcat tccagagatc agcatcatat
     6781 gctttaaaat catctttgtc aaaaatcata ggtcttctcc tttattgtgt gactagtcca
     6841 ttagtttgat tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc gtttctgcat
     6901 tttatcacaa gtatagccaa ctttttcata aaatgcatga gcacccagac gatgattggc
     6961 agaatttaag cggataaacc cataaccaca tctttttgct tcttcttcca acccttgtag
     7021 taaactttta ccaatacctt gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt
     7081 aaatcctgct ttggaataga gtgattcgta aacttcagcg tggacatatc caagtaagac
     7141 atgattagct gcatcctcat agccaagtag gaaatgatgg gaatcctgag acagtctagc
     7201 tagttggcta gccgtttcct ctggactaaa agtataaccc aaagcctctt ggttgatgtc
     7261 acatatcgct ttcacatctg tttcttgcaa atctcttagc atttcaagcc tcctcaaaag
     7321 aaatctctgg caaccgagca agaatatctt ctcgtttaat tgcgccttgg cgtaagattt
     7381 tcaccttgtc tccagacaaa tccacaatag ttgaatcctg tccagttaga aaagcatcgt
     7441 cttccagacc cagaacctct tggtcaaaat ccttcagaat ttgttcaaag gttacaccac
     7501 ttgcctgacc tgagatattg gcagacggcc caatcaaggg acctgtctct cgaattaaat
     7561 ccagtgtgat agggtgactg ggcatccgaa atccaatagt tgcaaggtca gaatttaccc
     7621 aatagggaac tcggtcattg gcttcgagaa taatggtcaa gggacctggc aaaaaggtct
     7681 ctacaagttt ttgtagataa gttggctgat tcttagaaaa gtgcaagata tcctcgaaag
     7741 aggcgatatt gagattgagt gccttatctc taggacgacg tttgagttgg taaacatggt
     7801 caactgcttt ttcatctaag gccttggcaa aaagaccata aacagtctct gtaggtagaa
     7861 cgacagctcc accattttcc aactcttgtc taatcctgtc catcatcaac cacaaccatc
     7921 ctattttgac caaattggtc tttgagtgtt cgaacttttt tttcaggaag atgttttcta
     7981 aaaagttcgg gaacactttg accttgcttg tatccaattt caaggtaaat cttaccacca
     8041 tccttgagat agtcttttgc atcttccgca attctacagt aaatagctag gccatcctcg
     8101 tctgcaaaga gagctagatg aggctccgaa tgcaaaacat tcaaacctac ctctgactca
     8161 tcttcacgag agatataggg tggattggat acaattatat catatttttc agaaatttct
     8221 gcaaaacaat cagatttttt aaaaaatata ttaagatttt gatcgctagc attctctgat
     8281 gcaagctcta aggcctcttg agaaacatct gctgctgtca ctgaccaatc tggtctattt
     8341 tttgctagag cgagagcaat agctccacta cctgttccaa tatccagaac tgagagattc
     8401 gtctcaagat tttcagttag aataagctcc actaactcct ctgtttctgg acgaggaatc
     8461 aaaacccgtt catccacctt taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac
     8521 tgagctggct tgtgagctgc tagttgctgg taaatatctt ctacaaattg tttttcttcc
     8581 tctgttgtca cctcctgctg gagggcaaaa ataaagtctg taaaagatag atttttcaga
     8641 ctacgataga caaaagagag gctttccgct tcctctcctt gtcttatcaa ctcttcttca
     8701 aaatttgaaa ataattgagc taatttcatt atttgtttaa ttcttctagt ttttgtgttt
     8761 ggtcataaag caccaaggca tccacaactt cgtccaattt accagacaaa atcgtatcta
     8821 gtttttggag ggtcaagccg atacggtggt ctgtgacacg gttttgtggg aagttataag
     8881 ttcggatccg ttctgaacgg tcaccagtac cgattgtcga cttacgctca gcgtcttgtt
     8941 catcctgagc aatctgagca aagtggtcag cgacgcgtgc acggataatc ttcatagcct
     9001 tctcgcggtt cttctgctgg gtacgttctt cctgcatctc aaccttgata ttggttggca
     9061 agtgaacgat acgaacggca gtcgcaacct tattgacgtt ctgtccacca gcaccagagg
     9121 cgtgatagat gtcgacacga aggtcttttg gatcaatgtc gtattcaacc tcttcaactt
     9181 ctggcataac aagaactgtc gctgtcgaag tatgaacacg gccttggctt tctgtcacag
     9241 gaacacgttg cacacggtgg gcacctgatt catacttaag cttagagtat acagactgac
     9301 ctgaaaccat agcaaccact tctttaaaac caccgacacc attcatagag gcttccatga
     9361 cttcaaagcg ccaaccttgg gcttccgcat acttttggta catagttagc aaatctccag
     9421 cgaaaagtgc cgcttcgtct ccaccagctg ctccacggat ttcaaggatg atattcttgt
     9481 catcgtttgg atcctttgga aggagcaaaa ttttcagttt ttcttcatat tcttcttttt
     9541 cagccttggc atctttgagt tcttgcttgg ccatttcttc caagtccgca tctccgcctg
     9601 attccttaat catctcttcg gcatcgacga tattttgaag gacttgttta tactcacggt
     9661 aggctattac ggtgtcacga ttggaagctt cttcttttga aagctccata aaacgcttgg
     9721 tgtctgaaac gacatcaggg tcactcagca attctcctag ttcttcataa cggtcttcta
     9781 cagcttgtag ttgatcatag atgttcattt ttcttcattc tccttattga tttcaggggc
     9841 aaaataatgt ttacggcaaa ccgagatata ggtttcatta ccaccaatct ggatctgttc
     9901 tccatcgtaa acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca
     9961 atactgacag atggtcttga tttcgtcaat cttgtctgct aaaagcaaga gatatttgga
    10021 accttcgaac aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc
    10081 taactcgtcc acaacacgag ctaggtcata aacatggtgg cgtttgagaa actgggcttc
    10141 atcgaccaaa acacagtaag gtttttctgg taggtctcgg atatagccaa agatatccgt
    10201 tgtttcctca atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac
    10261 accgtcacgc gtatccagag ccgaggtcat aatcacaaca ccttttcctt gctcctcgta
    10321 gttataggcc actttgagaa tctcaatcgt tttaccagag ttcatggtcc cataacgata
    10381 gtacaactgt gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt
    10441 atatcataat tttcttaagc tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac
    10501 tagtggagga agctattatg ccatttgtac gcatcgattt atttgaagga cgcacgctcg
    10561 agcaaaagaa agctcttgct aaggaagtaa cggaagcggt tgttcgcaac actggagcac
    10621 ctcaatctgc tgttcatgtc atcatcaacg acatgccaga aggaacttat ttcccacaag
    10681 gggaaatgcg caccaaataa gctagcttaa gcagaattgc ttaggctttt tcaatctcca
    10741 agtagcaccc attgaagaaa tagtctaaat ttgttacaat ttgaaaagag acttggaaaa
    10801 ttccaagaaa agagcaatta attaaaggaa acattatgat tacacgtgaa tttgatacca
    10861 tcgctgctat ctctactcca ctaggtgaag gggctattgg tattgtccgc ctgagcggaa
    10921 cagacagttt tgctattgtg caaaagattt ttaaaggaaa agacttgaac aaggttgcca
    10981 gccacactct caactacggt cacattattg atcctctgac tggtaaagtc atggacgagg
    11041 ttatggttgg ggctatgaag tctccaaaga ccttcactcg tgaggatatt atcgagatta
    11101 acacccacgg tgggattgcg gtgaccaatg aaattctcca gctagctatt cgtgaagggg
    11161 ctcggttggc agaacctggt gaatttacca aacgtgcttt tttaaacggt cgcgtagact
    11221 tgacacaggc agaggctgtg atggatatca tccgtgccaa gactgacaag gccatgaaca
    11281 ttgcggtcaa acaattagac ggctcccttt ctgacctcat taacaatacc cgtcaagaaa
    11341 tcctcaatac acttgcccaa gttgaggtca atatcgacta tcctgaatat gatgatgttg
    11401 aggaagctac tactgccgtt gtccgtgaga agactatgga gtttgagcaa ttgctaacca
    11461 atcttcttag aacagcccgt cgcggcaaaa tccttcgtga aggaatttca acagctatca
    11521 tcggacgtcc caacgttggg aaatccagcc ttctcaacaa cctcttgcgt gaggacaagg
    11581 ctatcgtaac agatatcgct gggacaacac gagatgtcat cgaagagtac gtcaacatca
    11641 atggtgtacc tctcaaattg attgatacag ccggtattcg tgaaacagat gacatagtgg
    11701 aacaaatcgg tgttgagcgt tcgaaaaaag ccctcaagga agccgacttg gttctactag
    11761 tgctaaatgc cagtgaacaa ctgactgcgc aagacagaca acttcttgaa attagccaag
    11821 ataccaatcg cattattcta cttaataaaa ccgacctgcc agaaacgatt gaaacttcga
    11881 aactacctga agacgttatc cgtatttcag tccttaaaaa ccaaaacatc gacaagattg
    11941 aagagcgaat caacaacctc ttctttgaaa atgctggctt ggtcgagcaa gatgctactt
    12001 acttgtcaaa cgcccgtcac atttccctga ttgaaaaagc agttgaaagc ctacaagccg
    12061 ttaatcaagg tcttgagctg gggatgccag ttgatttgct tcaagttgac ttgactcgta
    12121 cttgggaaat cctcggagaa atcactgggg atgctgctcc agatgaactc atcacccaac
    12181 tctttagcca attctgttta ggaaaataag aaaaatccat gatccttcat tcggtcatgg
    12241 attttattgt ctttattagt aatctggtct taagacccct gttacagttg ccttagttgc
    12301 ttcgtagtcg ccatctacga caaccttgat aatgcgtttg gcatcttctt ctggtgctgg
    12361 aacaagaggt agacgagtgg gtccagcttc aaatcccata tagttaagaa ttgccttaac
    12421 tggagcagga cttggataag agaagagagc attaacctta ggaatgaatt tacgctgaat
    12481 tgctgcggct ttcttcatat cgctttctgc aatggcagta aacatctcgt gcatttcatc
    12541 cccatttgta tgagaggcaa cagaaataac cccatccgcc ccaaggttca tggcatggaa
    12601 agcatctcca tcctcacctg tataaatcaa gaactcttca ggcttgtgct caatcaagta
    12661 agccatatta gccaagctag tacattcttt gacaccgata atatttggat ggtcagccaa
    12721 gcgaagcatg gtttctggag tcaattcgac aactacacgc cctggaatgt tatagataat
    12781 aattggtagg tcagaagcat ctgcaatagc cttaaagtgc tgatacatcc cttcttgaga
    12841 aggtttgttg tagtaaggaa caatagcaag cccagctgcg aaaccaccaa attccgctac
    12901 ttctttgaca aactcaatag agtcacgcgt atcattagta cctacacccg caatcaaagg
    12961 aacgcgtcca ttgacaacct tttgtacagc cgcaaacaac tccaactcct catcgtgggt
    13021 caaagttgga ctctcagcag tcgttcctgc gagaagaatt ccatccgtat gatgggccaa
    13081 taaatgctca atcaaggctg gaatagcatc aaagttaatg gaaccatcct catggaaggg
    13141 ggtaataaag gctgtaatga ttttacattc ttttaaatct tgataagaca cgaaaacacc
    13201 tctctatttc aaagaaggag ttcatctgaa ctcctaaacg atatgactat tttaattcaa
    13261 atttcaattc agctgttgga cgaaccaatc cacgttcatg aagagtttca gcaatctgaa
    13321 ctgagttcca agcagcacct ttgagaaggt tatctgaaac aacccacatg tgaattcctt
    13381 tttctgcatc caagtcttta cggatacgac caacaaaggt atcacgtgaa ccaactgcat
    13441 tgatggcttg aggatagatt tgatgaacta catcatcttc aagaacagca cctgggaagg
    13501 atgcgatagc tgctttgact tcttcaattg gagccacttc ctttgtttca atataaactg
    13561 actcagagtg agctgacaag actggaatac gcacacatgt cgcagatact gcaatgctat
    13621 catcttccat aattttctta gtttccttgg tcatcttcat ctcttcgtac gtgtaatcat
    13681 tatcagtgaa gacatcaatt tgtggaagag cgttaaaggc gataggataa tgtttcttgt
    13741 caccacctga aggcaagatt tccgcatgca aatcacgtgg tttcactcca tcattcaaga
    13801 cctcacgaag ttcacgttgt gtctcaagaa ttgctcccat accagcacct gaaacggctt
    13861 gataagttga aacaatgata cggtccaagc cccatttttg gcgaaccggc tcaagagcca
    13921 ccatcatttg gattgttgaa cagttagggc aggcaatgat tccgttgtgg gcatcaagtg
    13981 catgagcatt gacctctgga acaaccaaag gaacatctgg attttgacgg aaataagatg
    14041 tattatccac tactaccacg ccagctttta ctgcgtatgg tgcatactta gctgatgtcg
    14101 aaccacctgc tgaaaagaga gcaatatcaa ctccttcaaa agctgtttca gtcgtttctt
    14161 caatcgtaat atcttgatct ttaaatttca atgacttacc tgctgaacgt gcagaagcaa
    14221 ggtaacggat tttatcgatt ggaagtgttg attcttccaa catttttatc atctgagcac
    14281 cgacagcacc tgtcgcgccg actacagcaa ctgtatatcc cataaataac ctctttcgga
    14341 attttctaaa aatttctata atagaagtat tatactactt tttccatgaa ttgcaaagct
    14401 ttttcatcat tttttggaaa ataaaaatcc ccaatcgcta gactagggat taagaggcat
    14461 cttcatgtga tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc
    14521 ttatgctcaa tagtagcccg aagactacct atcgactcat cgcatctact attctactaa
    14581 agagaatgac ttttgtcaac agacgaaact ctttatactc ttcgaaaatc tcttcaaact
    14641 tcgtcagcgt cgccttgccg tatgtatggt tactgacttc gtcagtttca tctacaacct
    14701 caaaaacatg ttttaagctg acttcgtcag ttctatctac aacctcaaag cagtgctttg
    14761 agcaacctgc ggctagtttc ctagtttact ctttgatttt cattgagtat tagttttatt
    14821 tacacaggtg cataagaaat atattggaaa aattgggggc agacataaca aaaacccttg
    14881 taaatcaagg gcttttctgt ctatttaatg ctaattgccg ggattgaacc ggcgacctca
    14941 tccttaccat ggatgcgctc tgccaactga gctaaatcag cttacttaag aagtatacta
    15001 tattcagaaa aacttgtcaa gtttccttag aaattttcca taggaaaaag ccaggtaaga
    15061 actacctagc ttatcttctt ctatttactt aaatcaattc gacgaccaat tttaccaata
    15121 ataatcgctc caataatcaa tgaagcaaat tcaccgattc ctgttgtaaa ccaagtaagg
    15181 aagaatggta attctgctac aatatttaac tctgcagcga tagtaaacat ggaaattgaa
    15241 aagaggattg aaaagaagaa atgatctttt cgaatcaatc cgttaaagag gtaatccttg
    15301 ctatattttg caaaaagcca aacacctaaa ctgaggaata ctaaggttga accaccacca
    15361 acaaagacat ctagcagtcc gaagctaaag aaattagcaa tcatacaacc gatggtaact
    15421 ccgatgatgt acttaggatt gtaaaaagcc ataaagttca tcatttctga aatacgaaac
    15481 tgataagcac catagctgat ggcatttagg ggcggtgtga cagtcaaaac gacgtagata
    15541 gcagcgacga ttgcaatatc tgcaacatca cgaatagtta attttttcat cttttctcct
    15601 ttggcggtta tccgcgtgta atatgcttgg tgaaagaagc taagcaccaa gggttgattc
    15661 attcaacctt actagtatag cacaatagcc tgctttatgc tatacttaaa gcatgaaaaa
    15721 acctattcaa aaatttttta acaatgaaat cttagcctat ctcttttttg gccttgcgac
    15781 aactctagtt tcgattctct cacgactagt catttatcaa ctaagtcatc aggaactcct
    15841 tgctacggcc ttggcaaata ttatcggtat cttatttgcc tttatcacaa atgatacgat
    15901 tgtatttaag caaaaaaaga aaaatagact tatccgttta gtgaaatttt ctcttgctcg
    15961 cctttctact tttctgttag acttgttttt aacttttctc tttgtaaccc aatttcctca
    16021 catcataggg caattcgtaa ctgaaaacat tgataagata aatgctattg aaacaataat
    16081 tgcacaaata ttcattatta tcatcaatta tatcttgagc aaggtctata tttttagaaa
    16141 ataatgctcc atttatgagc cttttaattg ccttctataa tgatttagga tacaatgaaa
    16201 cacgaaacat tgaaaggaaa acagtatgtt aaaaaatcta aaatcgttct tgcttcgagg
    16261 aaatgttatt gaccttgctg tcggtgttgt cattgcctct gcttttggtg ctatcgttac
    16321 ttcacttgta aacgacatta tcactcctct tattttaaat cccgctttga aagctgctaa
    16381 agtcgaacgt atcgctcaac tttcttggca tggagtcggc tatggtaact ttttaagtgc
    16441 tattatcaat tttatctttg tgggtaccgc cctcttcttt attatcaagg gcattgaaaa
    16501 agcacagaaa ctgactggca taaagaaaga aaaaactgcc gaaaaaaaac caaccgaatt
    16561 ggaagtcctt caagaaataa aagctctcct tgagaaaaaa taatcgatta aaaggatcta
    16621 gcgcaaagct aaatcctttt ttctttactc tttgggtaac ttgcctgctt tttcaagcat
    16681 ttttttgata agataaggca tcttaacatt ctcccgccct tttttctcaa tcagtttttt
    16741 cacaaattct ggcatttgta aatcttcaga ttcagctaaa atgtttttcg tctcgtctga
    16801 aggaactaac tcatcaaagg tctcttcttc tgggagaaat tccttaaact cttgattttc
    16861 attgactcta actgtattga ccaaagcatc aatcaaacga gaatctgtat ttggcattgg
    16921 tggacgatgg tagtttaccc caaattcctg gcataagtca taacattcta catcattgtc
    16981 aaacaagacc tcaatatgct cactgatgaa actaataggt acaaaaatat aatggtctgg
    17041 atgttctgtc tgttctctga gatactccaa aacatctggt ttaatccatg gaataccaat
    17101 atcactctca ctctgccaag tgttggtata ttgttctgaa ctcaagccca gtttttcagc
    17161 gactagcttg ctattttcga aaatttggtc tatataagga tcaccaaagt ccaaggcaaa
    17221 aatgggcaca ctatgggctg aaaagatgac tttaaagctg tcttgcttta cttcttcttt
    17281 taaaatctta gcaatttcat ctgcccaata gtttaagagc gcttcttcct gataccagtc
    17341 cttaatgacc aaaaattgaa tttgtttgct ttctaaaaat ttttcatagc ccatgacaga
    17401 gtagaaagaa taatggggct ccaaaatcaa gcaaatacac tgttcaattc cgtctgcttc
    17461 catttgaccg atcacatctg gaataaaggg actggaaaac ttattagcaa agtagacact
    17521 gtattcattc cccagcctag cttctaccaa ggtaacctct tgacgggtaa ttttttgcag
    17581 aggcgtgcct ccaattcgta cataattatc atagagagtc tgaatctcgt ggtcttgggg
    17641 tctcacccca cgacgaatat ttgtgaaaaa atcagctaca ccttcaaagg taatctcttc
    17701 tggtgaaccg aaggtcatca ttaaaattgc ttttttcatg actgcttcct tgtgatgttt
    17761 ttatcaagtt tattttatca ttaattcatc gataagtaaa cgctaacata gggacattct
    17821 caatcttctg tcttttgttt ttctcttctt tctatgatac aatggaaaaa ataaattcaa
    17881 aaggagtttt tttatgactt atccaaatct cttggaccgc ttcttaacct acgttaaggt
    17941 caacacgcgc tctgatgaac actctactac tactccaagt acacagagtc aggttgactt
    18001 cgcaacaaat gtcctaattc ctgaaatgaa acgtgttgga ctgcaaaatg tttactatct
    18061 accgaatggt tttgctattg gaaccttgcc agccaacgat ccgtctttaa cacgtaagat
    18121 tggttttata tcgcacatgg atactgctga ttttaatgct gaaggagtca atccacaggt
    18181 aattgaaaac tacgatggtg gtgtgattga actagggaat tctggtttca aactcgatcc
    18241 agctgacttc aagagtcttg aaaaatatcc aggacaaacg ctcatcacaa cagatggaac
    18301 aaccttgcta ggtgctgatg acaagtcagg aattgctgaa attatgacag ccattgaata
    18361 tctaactgct catcctgaaa ttaagcactg tgagattcgt gttggttttg gtccagatga
    18421 agaaatcggt gttggtgcca ataaatttga tgcagaagat tttgatgtgg attttgccta
    18481 cactgttgat ggtggtccac taggtgaact tcagtacgag actttctcag ccgctggtgc
    18541 tgaattgcat ttccaaggcc gtaatgtcca ccctggtact gccaaagggc agatggtcaa
    18601 tgcccttcag ctagcaattg attttcataa tcaacttcca gaaaatgacc gacctgagtt
    18661 aactgaaggt taccaaggtt tttaccatct aatggatgtg acaggtagtg ttgaggaggc
    18721 gcgtgcaagc tacatcattc gtgattttga aaaagatgcc tttgaagcgc gtaaagcatc
    18781 catgcaatct atcgctgata agatgaatga agaacttggg agcaaccgtg tcactctcaa
    18841 cttgacagac cagtactaca atatgaaaga agtcattgaa aaagatatga ctccaattac
    18901 cattgctaaa gccgttatgg aagatctagg tatcacgcct attatcgaac caatccgagg
    18961 tggaacagac ggctctaaga tttcctttat gggaatccca actccgaata tctttgcagg
    19021 tggcgaaaat atgcacggac gttttgaata cgttagcctt cagactatgg aacgtgcagt
    19081 tgataccatc attggcatcg tacgtagctt ataaaagcta aaaagacgag gtagctcagc
    19141 tacttcgcct ttctttttat tctactggtt tttcttgatt tccagtagtt gtagaagatt
    19201 ctgttgtttt attttctgaa gttgattcag caggtttaga atctcttgta ttgcttggtt
    19261 tgttttcgtc gctagcagtt tcaatgttag attctgcagt tgcgtttggt tggttctcag
    19321 cactggtgtt atcaccattt gcttcagcat ttcttgctgg acttgtttct tcacttgcgc
    19381 tagcttttga ctggatttga tgattcaaaa ctagaatagc ttttgtcgat tcaagtaaag
    19441 ctgttttgtc tttactctta gcagaaagtt gatctaataa tgcagccacc ttatcaaagt
    19501 ccgcatcaga tccattatta ctttctaaat aagagtgaag cgacatgaga atatcgtaga
    19561 gtttttgata gagtacaagt gtctgaggat cttgctcagc attttccttt tcttgttgaa
    19621 gggcgctagc gatacgagtc aagacatctt ttacctgact gtttacttca tccaagtctg
    19681 catcagcctt gtttgtggca gcttttagat tttctacttc ttctgccaag gattgtctga
    19741 ttccttcttc atggatttgt tccaagagtt gatttgcctt gctcaaaaga ctttctactt
    19801 cttccttgct atctgtcgca gattattggt tgctatctac catgtattcc taaaacagga
    19861 gagttataat ccaagattac aaggccttac agaaataaga aatccagata agacaatgtc
    19921 cgtccaagac gctattcgct tcgcacagca gcgcggattc aatatgcttt aattttaaag
    19981 tttaggtgtc aagacctctt tttagtgtgc ccaaaattta gagaagtaat caatcaacta
    20041 acttttattt ttttcaaact ttcagtaaac tgacctaaag ctaactcaat ctgtctttgt
    20101 tcgataggct tgtctttgta gatgcttctg ctatcagcta gaagttgatc tacttttgcc
    20161 aagactgcct tctcatcaaa agttccaggt ggatagttgg attgcaggga tggaatcttg
    20221 tttttcaaag ccgcttcata tcccttagtt tgaaccttga tgtagtgatt gtggtcgcca
    20281 tgaggaatca caaaaccttc tgaatcttca cttataattc gattggcatc aaaaccatga
    20341 ccatcttctt cctcatggtg gacatgtagt gacggattac ttaatacaga actagaagaa
    20401 cttcctacct cttccgtgtt agagtgtgat gggggattgt taagagatga cttaggaata
    20461 tagtgatagt gatccccatg tcttactata taagcatcac ctgtatctct gacaatatca
    20521 ttagggttaa agacataacc atcatctact gcagaaacac cattattcgg tgtcaccggc
    20581 aaagattgac tgagagctgt agtattccct gataattata cttttgcgac tgctaattca
    20641 cctgccgaca agtcactctc aggaatgaaa tgatagtgac caccatgtgg tactatcgta
    20701 gattgaaata gaatatgagc aaattgataa ggggatttta aagtaatttc taacaatgat
    20761 ttagaaacta tgatgtgcta ttctaaattc aactcactat atataaccat catcggtagt
    20821 ataacgtccc tgtaattttg ctacagatac ttctgcacta gctcctttat cgtctttacc
    20881 atgttcttgt ttttggcgat tgatttcatc ttttgttcgt acattttctg catgagcttg
    20941 atctttaagg taaacataat actttccatc tcccttaata atatatcctc ccttaaccta
    21001 actgacgata tcttgatctt tcggctgata gttgggggct ttcattagta gctcttcact
    21061 aaagagcgca tcaaaaggaa ctttaccatt atagtagtga taatgatcgc catgagaagt
    21121 tacataacct tgatctgtaa tcttaataac aatttgtttt gcttgaattc cttctttttg
    21181 actaacctag tctggagtca aattttcagt cttcttagtg tctttattac tgtttacata
    21241 tgaaacacga tttttatctg tattggcctg ttagctatgt tggttcagag cataaacaca
    21301 cagacttaag gaaaggataa caacagatcc agctgctata tatttctttt taaatttcat
    21361 aattacctca tttctataat tatttatatg atgtcttcat tattaaatga ttaaataaat
    21421 taattaacca gttaattaat tagtaaatat tccacctctt tttaagttgt atgtcaagaa
    21481 attttatata ttaataataa aatgaaattc tcccaaagtc agagttttat ttctaacttt
    21541 tgagagaact tcatttttga ttcagacttt ttctactgct attccttacg ctatgagatc
    21601 agataaattc ttttttatca cttctccact tggcaatctt aattcaatcg ttccatccat
    21661 attgaatata acactatcta agcctaatcc gtaactagct gtaaattttt ctaatttttc
    21721 ttgtacagga tctactgctg gagcttcctc taatgctgga tctaacatag ggtcactccc
    21781 cacattccct tctggattca acattccatt atccgttgag ttttctggtt ttacaggttt
    21841 ttcgtttggt gcctctggta aagaatctgc tggtttattt tctgttggtt ggttctcaac
    21901 tgttccagta gatacttttc cagtttcaga tggtttattt tcaccatttc cttgaggtgc
    21961 ttctcctgta aaatctgcca tattcttttt aatgacttct cccgatggta aatataattc
    22021 aattgttccg tccatattaa acaagacatt ttctagcttc atcccataac tttcagcaaa
    22081 ttttgctact ttttcttgta caggatccac tgtaggaact tcttctaacg ttgaattact
    22141 agtactattc ccagtttcag aaagtttttc tttttctacc ttctcactag tctttggttc
    22201 ttctaccttt tcatcaagtt ttgagttttc ttgtgcttta ttccttttaa attgtggtag
    22261 aatacttggt ttatcagttt gattttcttt ttccaagata ggtacttcca caatataagt
    22321 cgattgattg tccaaataag catttgccat gaaggttaca ggaattttat ttccggccgt
    22381 tctggttgtt ccttggttta atttcggaat cggtaatttg atttcaccaa ctttatagtt
    22441 attttctaaa taagcatttc catgaaattc atcaaacact ctgactaaag catcagttcc
    22501 tttaggcact gcaaattgag ggttcactct taaataagta tcccctgcat ggaaaggata
    22561 gaaaatcgtt tgactggcca ttttgtaagc taaagaggtt ggaactgtaa atgtaccatc
    22621 ataacttact tctggataat cttttgaagc gatagtatac ttaaatgttt gtcctggtaa
    22681 ataaggctga tctaattcaa agtttgcaat attccctact ccttctccaa atactttacc
    22741 agatactttc tccaatactt ttccatctgg tgttattaat tttactagca tattgatacc
    22801 taattttttc tccaattcag gcggaaaact aaaagaaacg cgtttttgac cattggctag
    22861 agtaaagttt tgattattaa acgtactatt ttttaacaaa ttaacaacat tcgttaattc
    22921 ttctccagta taaactttat tcccttcttt tttagcaact ccttcttcgg gtttaaacag
    22981 ttcatagtta ctgtgagaat gaccaattcc aaccggttta tgttcatcaa tcggatctgc
    23041 atgatggtga tctccatgcg gataaataat cgcatttttt tctttattca cgacaatact
    23101 ttcacgtttg acaccatatt gtttcataat gccagcaatt ttttcttcaa tttttttatc
    23161 taaatctttc atttctttgg cattacttgg ataatcctgt tcatgagatg acaaagaatc
    23221 taatccatta tgactagttt taacttcctc taaatgtttt tgcgcagcct taatttgctc
    23281 ttctgtcaag tccttcttga agaaataatg attgtggtct ccgtgactca tgacaaaacc
    23341 tgattcatct tcagagataa tacgattagc atcaaatccg tatccatctt cttcatgttt
    23401 ctcatgtgaa gttcctggat tgattggaag agatggagaa ggtgttgcta gactattgtt
    23461 tggaagagtc ggttgcccaa tttgatttga ttttggaatg taatggaaat gatcaccatg
    23521 tcttacaata taagctgtag ccgtttcttc aacgatatct tttggattaa aaatataacc
    23581 atcagatgct gaagagagct ccttacttgt cgttaaagaa gaaggattgc ttgaaagact
    23641 gcctagacta gacactactt cattaggttt tgcatttgta gaaactgtag aaccagttcc
    23701 actgataggc accattctgg caatcttttc ttctaaggca gaaagcttgc tgtaaggaat
    23761 aaagtggtaa tggtcgccat gcggaatcgc aactccattt ggtgtacgac tgataatctt
    23821 agcagggtca aagaccaggc catctgattc actgtaacgt tgggcgctag gtgaatcata
    23881 gagttccttc aaaagactct ggagattttc agatttattt gctggcttgc tagttgatcc
    23941 ttttgctaca gattgcgtgt tattgtcact agctgttgaa gaatagctta actgactcgg
    24001 ttgcatattt tttccaacca gatgtgcttt agctgctgct aattcactag cagataaatc
    24061 gcttttggga atgtagtgat agtgacctcc atgaggaacg atataagcat tacccgtatc
    24121 ttcgataata tcagctggat taaagacata accatcattt gtcgtatatc gtccctgaga
    24181 ccttgctaca gcaacattag agttaacctt ctcattatct ttgacatgtt cttgtttttg
    24241 acgattgatt tcatctttag ttcgaacatt atcagcatga gctgcatctt tcaggtagac
    24301 ataatatttt ccatcgacct tgatgatata accacccttg acttcattga caatatcagc
    24361 gtctttaagt tgatagtttg gatccttcat caagagttct tcactaaaga gggcatcata
    24421 aggaactttc ccattatagt aatgatagtg gtcaccgtgt gacgttacat agccctgatc
    24481 tgtaattttg attacaattt gctcagcctg aattccttct ttctggctaa cctggtctgg
    24541 tgtcaagttt tcacttttct gacttgactg gctgccatcc acataagaga cacgattatt
    24601 gtccttattt tcctgcgaac gatgctggtt tagtgcatag gcacatagac tcaaggatac
    24661 gataacagct gatccagctg ctatatattt tttactaaat ttcataaatc cctcatttca
    24721 ataaatgatg aagttttttc tcaacttctt ttactttatt aaatagtttt ctaaaccggt
    24781 tatttaacca tttaattaac cagtaaatag tttactattt aaaattactt ttgtcaagtt
    24841 tctgttacgt ttttctaaaa aagagaagta acacgaaagg ttacttctcc ataaaatatg
    24901 ctccattcat tttactactg tatcggagcc ggttgacttt tttttaacaa agccaagaga
    24961 ctatctactt ctgctgaaat agtgttatta tctttcgttc cgagaagaag actacttttt
    25021 agaccagtca atgtctccat agcattttgt ctaatactag aatctgttac tttttctagc
    25081 aaggcctccg cctctgctat cttagcgtta ataacagaat tctctacttg aggaatttca
    25141 gtctcatctg tagtatcttc agcttcttcc tctgtctctt ccgtatcagt gcttggttta
    25201 taaagattat ctgctgaagg atttaaacca gcgtgattct ctttttcatc agattcaggg
    25261 tgagttggct cacttacttc atcatgtccc ttatcttcat caggtttact gtcttggtct
    25321 gccttatttt ta
//
LOCUS       DAVLCS010000028        24140 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLCS010000028 DAVLCS010000000
VERSION     DAVLCS010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24140
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.028"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(55..3231)
                     /gene="carB"
                     /locus_tag="VXC78_001380"
     CDS             complement(55..3231)
                     /gene="carB"
                     /locus_tag="VXC78_001380"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV0583445.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(3543..4622)
                     /gene="carA"
                     /locus_tag="VXC78_001381"
     CDS             complement(3543..4622)
                     /gene="carA"
                     /locus_tag="VXC78_001381"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV0583446.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(4672..5595)
                     /locus_tag="VXC78_001382"
     CDS             complement(4672..5595)
                     /locus_tag="VXC78_001382"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV0583447.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(5614..6135)
                     /gene="pyrR"
                     /locus_tag="VXC78_001383"
     CDS             complement(5614..6135)
                     /gene="pyrR"
                     /locus_tag="VXC78_001383"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV0583448.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(6346..6975)
                     /gene="nth"
                     /locus_tag="VXC78_001384"
     CDS             complement(6346..6975)
                     /gene="nth"
                     /locus_tag="VXC78_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV0583449.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(6975..7517)
                     /locus_tag="VXC78_001385"
     CDS             complement(6975..7517)
                     /locus_tag="VXC78_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV0583450.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            7686..7826
                     /locus_tag="VXC78_001386"
     CDS             7686..7826
                     /locus_tag="VXC78_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blpT protein"
                     /protein_id="HEV0583451.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQVTADDIRLQELLNTTMQELKKQ
                     KS"
     gene            8241..9800
                     /locus_tag="VXC78_001387"
     CDS             8241..9800
                     /locus_tag="VXC78_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0583452.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(9949..10848)
                     /gene="htpX"
                     /locus_tag="VXC78_001388"
     CDS             complement(9949..10848)
                     /gene="htpX"
                     /locus_tag="VXC78_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV0583453.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(10850..11410)
                     /locus_tag="VXC78_001389"
     CDS             complement(10850..11410)
                     /locus_tag="VXC78_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV0583454.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            11504..12217
                     /gene="rsmG"
                     /locus_tag="VXC78_001390"
     CDS             11504..12217
                     /gene="rsmG"
                     /locus_tag="VXC78_001390"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV0583455.1"
                     /translation="MKPETFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12520..13803
                     /locus_tag="VXC78_001391"
     CDS             12520..13803
                     /locus_tag="VXC78_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV0583456.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFIPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(13998..15569)
                     /gene="ffh"
                     /locus_tag="VXC78_001392"
     CDS             complement(13998..15569)
                     /gene="ffh"
                     /locus_tag="VXC78_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV0583457.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15581..15913)
                     /locus_tag="VXC78_001393"
     CDS             complement(15581..15913)
                     /locus_tag="VXC78_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV0583458.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(16004..16381)
                     /locus_tag="VXC78_001394"
     CDS             complement(16004..16381)
                     /locus_tag="VXC78_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV0583459.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            16453..17757
                     /locus_tag="VXC78_001395"
     CDS             16453..17757
                     /locus_tag="VXC78_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0583460.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESQNPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            17770..18576
                     /gene="yidA"
                     /locus_tag="VXC78_001396"
     CDS             17770..18576
                     /gene="yidA"
                     /locus_tag="VXC78_001396"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV0583461.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(18631..18702)
                     /locus_tag="VXC78_001397"
     tRNA            complement(18631..18702)
                     /locus_tag="VXC78_001397"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18667..18669),aa:Arg,seq:cct)
     gene            complement(18744..19091)
                     /gene="rplS"
                     /locus_tag="VXC78_001398"
     CDS             complement(18744..19091)
                     /gene="rplS"
                     /locus_tag="VXC78_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV0583462.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(19210..19539)
                     /gene="crcB"
                     /locus_tag="VXC78_001399"
     CDS             complement(19210..19539)
                     /gene="crcB"
                     /locus_tag="VXC78_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0583463.1"
                     /translation="MVIVYLAIACGFGALVRYLFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(19533..19907)
                     /gene="crcB"
                     /locus_tag="VXC78_001400"
     CDS             complement(19533..19907)
                     /gene="crcB"
                     /locus_tag="VXC78_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0583464.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(19904..20170)
                     /locus_tag="VXC78_001401"
     CDS             complement(19904..20170)
                     /locus_tag="VXC78_001401"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV0583465.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(20286..20729)
                     /locus_tag="VXC78_001402"
     CDS             complement(20286..20729)
                     /locus_tag="VXC78_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV0583466.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            20833..21768
                     /locus_tag="VXC78_001403"
     CDS             20833..21768
                     /locus_tag="VXC78_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV0583467.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            21822..22106
                     /locus_tag="VXC78_001404"
     CDS             21822..22106
                     /locus_tag="VXC78_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV0583468.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(22163..22741)
                     /locus_tag="VXC78_001405"
     CDS             complement(22163..22741)
                     /locus_tag="VXC78_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEV0583469.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSTAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(22716..23729)
                     /gene="efeB"
                     /locus_tag="VXC78_001406"
                     /pseudo
     CDS             complement(22716..23729)
                     /gene="efeB"
                     /locus_tag="VXC78_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
     gene            complement(23732..24140)
                     /locus_tag="VXC78_001407"
                     /pseudo
     CDS             complement(23732..24140)
                     /locus_tag="VXC78_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT         7079 a         5437 c         4619 g         7005 t
ORIGIN      
        1 ttagtattcc tgtgtactgt tctaaattca gtctgctata tcttattttt ctatttaaat
       61 cgcttctgta acaaagctac gactttcaag taccttaagc atggcattag ctgtatctag
      121 cgctgtgaag aggggcaccc cgtgttcaat ggctgaacga cgaatttgct caccatcttc
      181 gtcagcagtt cgttttgttc ctactgtgtt aatgatagct tgaattcttc ctttgcgtac
      241 aaaacttggg atatccttat cgtcatcacc aatcttacca acaggttggg cttgcaagcc
      301 atgactagca aagaaggctg ctgtcccttc tgtcgcaagg attccataac caatgttttg
      361 gaaacgacga gccaagttca aggcttcttc tttggcatca tcagcgatgg taaagacgac
      421 attaccaaaa gttggcaagt gtagataaga agcttcaaag gctttataga gagctttttc
      481 caaagtagca tcagaaccca taacttcacc tgttgacttc atttcaggac cgagcaagct
      541 gtctacctta gctagtttgg taaaggagaa gacaggtgcc ttgatatgaa cacgggtgct
      601 ttcagggtaa agtccatttt ggtagccaag ttctgataaa ctttgaccaa gaatgagctt
      661 ggtcgctact tgagccatag gaatattggt taccttagat aggaatggaa cagtacggct
      721 ggcacgtgga ttgacctcaa taacgtagac tttttcatcc ttgataacaa actggatgtt
      781 catcattcca aggcagtgaa gaccgattgc taagcgtttg gtgtagtctg cgatggtctc
      841 ctgaaccttt tgcgacaagg tttgtggtgg gtaaacagcc attgagtcac ctgagtggac
      901 accagcacgt tcgatatgct ccatgatacc aggaatgagc acatctttac catctgaaat
      961 ggcatcaact tcgcactctt gcccaacgat ataagagtcg acaagaactg ggtgatctgg
     1021 actagcctta acagcagttc gcatgtaaga acgaaggtct tcttcgtttt caacgatttc
     1081 catggcacgt ccaccaagta cataagatgg gcggacaaga actgggaagc caatcttacg
     1141 agctgcaaga gctgcttctt cttcattggt agccgtttgt cctggtggct gtggaatatc
     1201 caattctttg agagcttgct cgaagaggtc acggtcttcg gcacggtcta ggtcagcaac
     1261 ctgtgtacca aggatggtca cacctgcttt tgccaatggc tccgcaaggt tgatggctgt
     1321 ttgaccacca aactgaacga taactccctt tggttgttcc aagtcaatga cgttcataac
     1381 atcttcgaat gtcaatggct caaagtaaag cttatctgat acagagaagt ctgttgaaac
     1441 ggtctctggg tttgagttca tgatgatagc ttcataacca gctgcctgga tagccttaac
     1501 agagtgaacg gttgcgtagt caaactcaac cccttgaccg atacggattg gacctgaacc
     1561 taggacaagt acagattctt tatcagatct gatagattca ttttcccaac cataggttga
     1621 atagaaatat ggcgtttcag agtcgaactc tgccgcacaa gtatctacca tcttataaac
     1681 tggaacaatc ttgttttcca agcgaagttg gcgaacttga tcatcagtcg ttccccagag
     1741 ttcagcaatc ttacggtctg agaaaccatt aagtttggct gttttcaaaa cttctagatc
     1801 ttgtggatga gcacccaatt cttgctcaat ttcaaagata tgcaagagtt tatcaagata
     1861 gaagatatca atttttgtaa gctctgcaat ttcttcaggt gtgtagccac gacgaatggc
     1921 ttctgatacg tagaagagac ggtcatcttg ggctttgaca accttttcaa tcaaggcatc
     1981 atcagaaact gctgcaagtt caggtatttc attgtggtgc accccaattt caagggagcg
     2041 gcaggccttg agaagagatt cctcgatgtt acgaccgatt gccatgactt ctccagtcgc
     2101 cttcatttgt gtaccgagac ggcgttcacc cttttcaaac ttgtcaaatg ggaaacgtgg
     2161 aatcttagca actacgtagt caagggctgg ttcaaacatg gcataggttg aacctgtaac
     2221 tgggtttata acctcatcca aggtcaaacc tactgcaatc ttggcagcca acttagcaat
     2281 cggatatcct gtcgctttag aagcaagggc tgacgaacgt gatacacgag ggtttacttc
     2341 gataacataa tacttgaagc tgttaggatc aagagctagc tgaacattac atccaccttc
     2401 aatcttgagg gcgcgaataa tgctcaagct cgcatcacga agcatttggt tttcatagtc
     2461 tgacatggtt tgcgcagggg caaatacaat ggaatcccct gtgtgaatcc caactgggtc
     2521 aaagttttcc atgttacaaa caaccaaggc attgtcagct gagtcacgca tcacttcgta
     2581 ttcaatttcc ttaaaaccgg caatcgaacg ctcaatcaaa cattgggtaa caggtgacaa
     2641 tttcaaacca ttttcagtga tttcacgcaa ttctttttcg ttggcacaca taccaccacc
     2701 agtaccacca agggtaaagg ctggacgaac gatgactggg tagccaattg tcgctgcaaa
     2761 ggcaactgct tcttctactg tgttaacaat ttcagattct ggaatgggtt gctcaagctc
     2821 ttccatcaat tgtttaaaga ggtcacggtc ctccgcttgg tcaatggcag ataatttggt
     2881 acccagaagt tcaacgccaa gctcgtctag gataccattt ttagataatt ccatggccat
     2941 gttgagacct gtctgaccac cgagtgttgg tagcaaggca tctggacgtt ccttacgaag
     3001 aatacgtgtc acaaactcaa gtgtaatcgg ttcaatgtaa accttgtcag caatttcctt
     3061 gtccgtcatg atggttgcag gatttgagtt aaccaaaaca acctcataac cttcctcttt
     3121 caacgacaag caagcctggg tcccagcgta gtcaaactca gcagcctgac caataataat
     3181 cggaccagaa ccaatcacca taattttttg aatatcagta cgtttaggca tagtttatga
     3241 tacaaagccc gtaaagaaca cagtgaaaat aggaaactcg gcgcagacgc cttcagcgtc
     3301 aagacgatgt ttatcttttt cacacagttc ttagggcgtg ttcacttccg cgaacaatgt
     3361 atcttctcct ttctattcgt cgcctctcag ggcgacatta aataagatac aaaggacgaa
     3421 tagaaagcga ttgaatttta agaaatcaag gaaggattga caatccaagt tggtttctct
     3481 aaattctgag ctttccgtcc gtgttcagtt acataaattc tccgacgagc ttttactcgt
     3541 tcttagtttg attgtttaaa aacttccatc atctcgataa actcgtcaaa taggtagcta
     3601 gcgtcgtgtg gcccaggagc tgcatctggg tggtattgaa cagagaaagc aggttggtat
     3661 ctgtggcgca caccttccac tgacttgtca ttgatttctt cgtgggtaat aatcaagtgc
     3721 tctggcaaat cctcgcggct gactgcataa ccatggttct ggctggtgaa gtctactcgt
     3781 cctgttgcga tttcacgtac cgcatggttg aatccacgat ggccaaactt catcttatag
     3841 gtcttagccc cgtttgccat tgcaaagagt tggtgtccca tacaaatacc aaagattgga
     3901 atttttcctt gtacaccgcg aatcatgtcg agtgcttgtg gaacgtcttc tgggttacct
     3961 ggaccatttg acaacataac tccatcagga ttgagatgga gaatttcttc agccgttgtc
     4021 gaataaggaa caactgtcac gttacagttg cgtttagaaa gttcacgtag gattgagtgc
     4081 ttgagaccaa agtccactag caccacgctc aaaccaactc ctggagctgg ataagacgtt
     4141 ttagtagaaa cctgtttgat attgtctgtc ggtaaaactg ttgcttggag ctggtccgtc
     4201 acatggtcca tactgtcccc aacatgggtc aaggttgcac gcatagtacc atgcttacgg
     4261 ataatcttgg taagagcacg cgtatcaatt cctgaaatcc ctggaatttt cttggctttc
     4321 aaaaattcat ccaaggtcat ttggttgcgc cagttgctag ctctacgcgc ttcttcaaaa
     4381 acaacgactc ccttacaagt tggaataatg gattcataat catcacgatt aataccataa
     4441 tttcctacca aaggataagt aaaggtcaag atttgtccat tataagactg gtctgtaatg
     4501 gattcttggt agccggtcat ccctgtatta aagacgattt cgcctgttac atcaatatct
     4561 gctccgaagg ccttgccttc aaaaactgtg ccatcttcta atactagaat tctttttgtc
     4621 atattttcac ctctcgtgga cgctcactgg cgtcttttaa cgtcttgtgt tttagttggc
     4681 gtttctactc gctagtacgg attctaagat tgccattcga acaaagacac cattggtcat
     4741 ttgttggaca atccgtgatt ttggtgcttc aaccaagtgg tctgctattt ctacatcacg
     4801 attgattgga gctgggtgca tgaggattgc tgtttctttc aaacgatcgt aacgttcttg
     4861 agtcaagcca tgttgggcat ggtagtcttc ttttgaaaat acagctccac tatcatggcg
     4921 ttcgtgttgc acacggagaa acatcatgac atcaacctga tcaatgattt catcaatggt
     4981 tacaaactgt ccatagtctg caaactcttg acttctccat tcctcaggtc cagcgaaaaa
     5041 gagttcagct cccaagcgtt tcaaaatctg catattggat ttggcaacgc gtgagtgatc
     5101 caagtcacct gcaatagcaa ctttaagacc ctcaaagtgg ccaaattcct cataaatggt
     5161 catcaaatca agcaagctct ggctagggtg ttggcccgaa ccatctccac cattgatgat
     5221 ggaagtcgta atcgttggac tagcaatcaa ttctctatag tagtcgacct ctggatggcg
     5281 aatcacacag acatccactc ctaaagcaga cagagtcaaa atggtgtcat aaagtgtctc
     5341 acccttatta accgaactag tcttcacatc aaagtcaagt cgttccaatc caagtttaat
     5401 ctctgcgact tcaaaggact tatgtgtccg tgtagaatcc tcaaagaaga gattggaaac
     5461 aatcggatgg tcttcatagg gaagctgggc tccattttta aactcaattc ctcgcttgat
     5521 caatttcatt acttgatcga cagtgaggtc ttccatggac accacatggt tcaatgcttg
     5581 ttgattttct gacatggcta ctcctttaac tttctaagct tcttcagtaa tcagaactct
     5641 gtcttggtca tcaagttctg tcatctctac gatgatttct tcagaacgac tggttgggat
     5701 attttttcca acgtaatctg gacggattgg caattctcta tgtccacgat cgactagaac
     5761 tgctaaactc acacgcgcag gacgaccatg accgacaata ttatcaatag cagcacggat
     5821 ggtacgacct gtatagagca catcatccac caagataact tcgcggtctg tcacatcgac
     5881 agaaaccaaa gaagtatctt ctccactttt aacatcatca cggaaaggtt tagtatccaa
     5941 ttccacaaca ggaactgaaa gattttctaa ctgcttcaaa cgttcttgga ttcggtgggc
     6001 aataaagaca ccacgagttt taataccagc caagacgatc ttattcaaat ctttgttgcg
     6061 ttcgataatc tcataagtaa tacgcgtaat cgctcgtttg acggtcaatt cgtctacaac
     6121 ttcttttgtt ttcatgacaa acctccaaaa agaaaagtct ccttaaacaa ggagacttga
     6181 aatttatagc caagcgagcc ctactgcaca cagtgtagac ttcacccttc tactttatcg
     6241 cgctccttgc ctgcctcacg ggacaggttt aaaggaatat ttagttatca tttactatag
     6301 cacaaagcat gcttaaaatc aagcaaaaag tttcaatgta gcatcttaca aattgctaaa
     6361 atcatataat tgtgggtact ggtcacactc tggatttttt ggatggcaaa tggctcttcc
     6421 aaaataaatc atggcctgat gggcagctaa ccactgctca ggcggcaaga tatccatgac
     6481 ccgcttttcc acctcaagtg gcgtcgctga ttttttgaca atatcgtggt gtttgcaaat
     6541 acgctccaca tgagtatcca ctgcaaaggc tggaatccca aatcctacac tcatgacaac
     6601 attggctgtc ttgcgaccaa cacctgccaa actctccaat tcttcacgtg tctgagggac
     6661 ttgaccatca aaatcgtcta gtaactgttg ggcacatttt ttaaggaatt tagctttatt
     6721 ccgatacaat cccaagcgag aaatatgtga agcaatctca ctctctgtcg ctacagacat
     6781 agcttggggt gttggaaagg caacaaagag acctggtgtg gccttattta ccgctgcatc
     6841 tgtcgtctgg gctgataaca tgaccgcaac caggagttca aaatgattgg taaaatcaag
     6901 actaggcttg gcatctggga agagggcaat gatttcttct agcacctttc gtgctcgttt
     6961 ttttgacaag accattattc atctccgtca aatagtcctt gtaagccagc aaaaggactg
     7021 ttttcttctt tctttactgc ttgttgagct tggtattctt cctctgtcat gatttgccag
     7081 tcatttcctg agacaaatcc ttgaccagct tcttcttcag ccgtcaagac cttgatagga
     7141 atgtttagca ggatattgtc tgatacactc tcagcaaggt caagcgcccc attttcgatg
     7201 ggcaagacca agtcatcatc taaaacttct tgatctagct ggttagttgc gccttccatg
     7261 aaaacttccg tgactggata agattcaact aactcaactg gctccatact gcgactcgaa
     7321 gcaagaacaa tggtataaga tagttgataa tctaagaaat acatacggtc ttcatattgt
     7381 actttcccaa ctgcaaggat atcttttaca tctaaaattt cttgattacg tgcacgcagg
     7441 tcatcaacta aatctaacgt ttgttcaaag ttcaaacctt cagactgctt acgaatttct
     7501 tgaatattta atttcatact tcctccataa agatttactc tcttgattat accatgaaaa
     7561 ggctacaaat cagcacacca aactttgtaa ttaaaattca aattttaaca tatttactat
     7621 gatagtttta ttttttagtg ctatactata gggaaagagt acatcagatc aaggaggatg
     7681 ctcacatgga agacaagaaa ctcattcaac tcctatccaa gttaaataaa agctaccaaa
     7741 actgtaaaca ggttacggca gatgatattc gactacaaga gctgctaaac actactatgc
     7801 aagagctcaa aaaacagaaa agttgaacaa cagtatctta attaatcttg agaaatttta
     7861 ccaacccacc agtcctctga ttggactggg tagcctaaaa ctaaacaatc aagcacgcac
     7921 tgcttggcga aactatgata aaatccatta cgagtatgtc aaacacgtac taagtctcta
     7981 tggacctgtt tttggatttt agagcataga atttccagtt ttctgttgac aaaatttcct
     8041 taaaggtata atataaagat actaatactc ggaggtaagg gagacatgaa caactaagtc
     8101 tatcaaataa agaaccttta tttagtagat cttgtttttg tctctttttg tgtgctcttt
     8161 tatgctcttt ttctggcatg ttaatagagt ttttttgaca tagactttgg gctctactag
     8221 gtaaagtaga gctttttgtt atgcactatc gacattctag aaagggcaat agtatgataa
     8281 aaatcaatca cctgaccatc acacaaaaca aagatttacg agaccttgtc tctgacctaa
     8341 gcatgaccat acaagacggg gaaaaggtag ctattattgg cgaagaagga aatggtaaat
     8401 caaccttact taaaacttta atgggggaag atttgtctga tttcactatc aagggagaca
     8461 tccaatctga ctatcagtca ctggcctaca ttcctcaaaa acttcccgag gagctgaaaa
     8521 agaaaacttt acacgactac ttctttttag attctattga tttagactac agtatcctct
     8581 atcgtttggc ggaggaattg cattttgata gcaatcgttt cgcaagtgac caagagattg
     8641 gcaatctatc agggggagaa gctttgaaaa ttcagcttat ccatgagtta gccaaaccct
     8701 ttgagattct atttttagat gaaccttcaa atgacctaga ccttgagaca gttgattggc
     8761 taaaaggcca gattcaaaag accaggcaaa ccgttatttt catttcccat gatgaagact
     8821 ttctttctga aacggcagac actattgttc acttgcgact ggtcaaacac cgtaaagaag
     8881 cggaaacgct agtagagcat ttagactatg atagctatag tgagcagaga aaggctaatt
     8941 ttgccaaaca aagtcagcaa gctgctaaca accaaagagc ctacgataaa accatggaaa
     9001 aacatcggag agttaagcaa aatgtagaaa ctgcgcttcg agctaccaaa gatagtactg
     9061 ccggtcgcct attggctaaa aagatgaaaa ctgtcctctc acaagaaaaa cgctacgaaa
     9121 aggcagctca gtccatgact caaaaaccac ttgaagagga acaaatccaa cttttctttt
     9181 cagacatcca accattacca gcttctaaag tcttagtcca actggaaaaa gaaaatttgt
     9241 ccattgacga ccgagttttg gttcaaaaac tacaactaac tgtccgtggc caagaaaaaa
     9301 tcggtattat cgggccaaat ggtgttggga aatcaactct gttagccaag ttacagagac
     9361 ttctgaatga taaaagagag atttcacttg gttttatgcc acaagattac cacaaaaaac
     9421 tgcaattgga tttatcccca atagcctatc tcagtaaaac tggggaaaaa gaggaactac
     9481 agaaaatcca atctcaccta gctagtctca atttcagtta tccagaaatg cagcatcaaa
     9541 ttcgctcctt atctggcgga caacagggaa aactcctgct tttggattta gtcctgcgca
     9601 aaccaaactt tctcctgctg gatgaaccca cacgaaactt ttctcccact tctcaacccc
     9661 aaatcagaaa actctttgcc acttatcctg gcggtctcat cactgtttcg catgaccgtc
     9721 gtttcttaaa agaagtctgc tcgatcatct atcgcatgac agaacacggt ttgaagctag
     9781 ttaatttaga agatttataa atttgcaaca tagcagatag gtggggcaaa aacacaattt
     9841 taggagaaaa agaagtaaat cttcccatag taaaacgcat aatatcaagt tttcacacct
     9901 gatattatgc gtttttcaga ttttaaagac ttttttccag ccttcatttt acatatgttt
     9961 taaacgttca atccgttctg agataggtgg gtgggtataa aagagttttt ggaacccccc
    10021 acctttcttg ggatcattga tataaagggc actgctagca tcatcgacgt ggcgactcat
    10081 aggtttgcta ttgtccaact tatctagggc attaatcatt ccctggggat tgcgagtcag
    10141 ctcgacacta gatgcatctg ccagaaattc cctctgacga gaaatagcga gctgaaccaa
    10201 ggttgcagcg agaggtgcca gtacaatagc tagtagggaa accactagca taatgatttc
    10261 aagaccattt ccatctcggt catcatcact tcgtctgcga cctgctccac cccaccacat
    10321 catacgacct gccatactag aaagcatggt gatagcacta gcaagggcaa ctgcaatagt
    10381 cgaaatacgg atatcataat tacgaatatg actgacttca tgtcccataa cagcttctag
    10441 ttcttcacga ttcatgatag ctagtagacc tgaagtcgca gcaacagccg cattttgagg
    10501 attagaacct gtcgcaaagg catttaaggc tggatcatca atgatgaaaa cacggggcat
    10561 aggaatctga gcgaccagag ccatatcttc cactacatgg tagaggtctg gtgccgtttg
    10621 ctcatccacc tcacgcgctc cattcatgga catgacaatc tctgtcgatt gaaaaatcat
    10681 agacaaagcg tagataaagc cgataatcag tgcgataacc aaaccaccaa gtccagatct
    10741 tataaagaga taaccaaccg cataaccaac aagagctaag agtaggaaaa ataccagcaa
    10801 caaaatccag gtttttcgtt tattgcttgc aatttgatca aacaacatct tagtcaccta
    10861 aaccgctaaa atcaacttta ggaaccgact tttcctcttc aggtgtttga aggaaatctg
    10921 ccgctttaaa tccaaacatt ccagcgataa tattgctcgg gaaagtttct aattttacat
    10981 tgtagttgct gacaacactg ttatagagtt gacgagagta agaaatttta ttttctgtgt
    11041 ttgtcaactc ctcttgcaat ttaacaaagt tagcactagc tttcaaatct ggatagcttt
    11101 ctgcaactgc aaaaatacct gaaacttgac gagtgagggc atcactggct ttcatagctt
    11161 ctgctggtga agtcgctgcc gccacttggt tacgtagttc tgccaccttt tcaagggtag
    11221 aaccttcata tttggcataa ccttttacag tctcaatcaa gtttggcaag aggtcatttc
    11281 gacgtttcaa ctgaacatca atctgactcc aagcctcctt ggtttgcata cgattcttaa
    11341 ccaaaccgtt atagctaaca atcacaaaaa taacaataag agcgataact ccaagaataa
    11401 tccaagtcat gatataagtc ctttctactt ttagattagt accagtatat caaattttta
    11461 atgattgtgg taaaataaga tgatactaaa gaaggaaata actatgaaac cagaaacatt
    11521 ttacaacttg cttgccgagc agaatcttcc actttcggac cagcaaaaag aacaatttga
    11581 acgttatttt gagctcttgg tcgagtggaa tgagaagatt aatttgacgg cgattacgga
    11641 caaggaagaa gtttatctca aacattttta cgattcgatt gcacccattc ttcaaggttt
    11701 gattcccaat gaaactatca aacttcttga tatcggggct ggggcaggat ttcctagtct
    11761 accaatgaaa attctctatc cggagttaga tgtgaccatt attgattcac tcaataagcg
    11821 catcaacttc ctacaactct tggctcaaga actggatttg aacggagttc atttctacca
    11881 cggacgtgcc gaagattttg cccaagacaa gaacttccgt gctcaatatg attttgtaac
    11941 agctcgtgcg gttgcccgta tgcaggtcct atctgaattg actattccct accttaaggt
    12001 tggtggaaaa ctattggcac tcaaggccag caatgcgcct gaggagttgt tagaagctaa
    12061 gaatgccctc aatctccttt ttagtaaggt cgaagacaat ctcagctacg ccctaccaaa
    12121 tagagatccg cgttacatca cagtggtaga aaagaaaaaa gaaacaccaa ataaatatcc
    12181 acgtaaggct ggtatgccaa ataaacgccc gctttaaatt tttaagtaaa aaaatattta
    12241 caaaatcaac ctcgctcttt tatttctagg ctcgggaaaa aatgatttac aaaatcagcc
    12301 tcgctctttt atttctaggc tcgggaaaaa atgatttaca aaatcatttt tttctgctat
    12361 actatcctaa gcaaaggttt ttaatgtcat cccgtgaggt gacgaagacg caaaaatatt
    12421 tgaaactctt taaagtctag attttagaga agtcttactc tgagggccta ttgctgtaaa
    12481 ataatgggct cttttctgat gcccaaaagt gaggtttata tgaaacaaga atcaactgtt
    12541 gatttgttat tagacgttga ccaacgtcct tcggctggaa aaggaattct ccttagcttc
    12601 caacacgttt tcgccatgtt tggtgcgacc atcttggtac cattgatttt gggaatgcct
    12661 gtatctgttg ccctttttgc ttcaggtgtt ggaacactca tctacatgat tgctactggt
    12721 tttaaagttc cagtttatct aggttcttca tttgccttta tcacagctat gtcactggct
    12781 atgaaagaaa tggggggtga tgtatctgct gcccaaacag gggttatctt gactggtttg
    12841 gtctatgtcc ttgttgctac cagcatccga tttgtaggaa caaaatggat tgataaactc
    12901 ttgccaccaa tcattatcgg tcctatgatc atcgttatcg gtcttggact tgcaggttca
    12961 gctgttacca atgcaggtct tgtagcagac ggaaattgga aaaatgctct ggtagccgtt
    13021 gttactttcc taattgctgc ctttatcaat acaaaaggaa aaggcttcct acgaatcatt
    13081 ccattcctct ttgccattat cggtggttac cttttcgcac taactcttgg cttggttgac
    13141 tttataccag ttcttaaagc caactggttc gaaattcctg gtttctactt gccatttagc
    13201 acaggtggtg cctttaaaga gtacaatctt tactttggtc cagaagccat cgctatcttg
    13261 ccaatcgcta tcgtaacaat ttctgaacat atcggagacc atactgtttt gggtcaaatc
    13321 tgtggtcgtc aattcttaaa agaaccaggt cttcaccgta ctcttcttgg tgacggtatc
    13381 gcaacttctg tttctgcctt ccttggtgga ccagccaata caacttacgg agaaaataca
    13441 ggggttatcg gtatgactcg tatcgcttct gtctcagtta tccgtaacgc tgccttcatc
    13501 gcgattgccc tcagcttcct tggtaaattc actgccttga tttcaactat tccaaacgct
    13561 gtacttggtg gtatgtcaat ccttctctat ggggttatcg ccagcaatgg tttgaaagtc
    13621 ttgattaaag aacgtgttga tttcgctcaa atgcgaaacc tcatcatcgc aagtgctatg
    13681 ttggttcttg gacttggagg agctatcctt aaacttggtc cagttacact ttcaggtact
    13741 gccctttcag ccatgacagg aatcatcttg aacttgatct tgccatacga aaataaagac
    13801 taagagtcta aatacaccta atccactcag acagctgagt ggatttttcg tataccataa
    13861 taaaagtgtc ttaacaaaat tattaaaatc aaaaaacgta taatatcaga tattctaaaa
    13921 ccttgatact gtacgtttta tcatagaaat ttttacttta ttttctcatc aaatgagatt
    13981 tgcatcaatc tcttgtctta cttgcgtttc ttcttcgctt tcttcatttt gttagccata
    14041 cgtttcatgg actgtttcat ggcaaattca ccaattttac ctttcaaacc gccaccaaac
    14101 atctggctca tatctggcat tcctgctcct ccgagagctg ataagtcagg cataccgcct
    14161 tgtcccatca ttccttcaag ggcagacata tccattcctc ccatatttgg catattttta
    14221 ggaaggttat ttggattaat ccccatttgc ttcatcattt tattcatatc cccagacata
    14281 acaccctgca tgagctgttt agcctggtta aagtccttga tgaatttatt gacttcgacg
    14341 aatgtatttc cagaaccagc agcaatacga cggcgacggc ttggatttaa caaatctggg
    14401 ttttcacgtt cttcaggtgt catcgaagac acaatcgcac gtttacgagc aatctggcgt
    14461 tcatccacct tcatgttttg aagggctgga ttgttggcca tacctggaat catcttgagc
    14521 aagtcttcca tcggccccat attttgcacc tgatctaatt gatcgatgaa atcattaaaa
    14581 tcaaaggtgt tttcgcgcat cttctcagcc atttcaaggg ctttttgttc atcgtattcc
    14641 tgagaagctt tctcaatcaa agtgagcata tcccccatac caaggatacg gctagacatg
    14701 cggtctgggt ggaaggtttc aatgtccgta atcttttcac ctgtaccagt gaacttgatt
    14761 ggttttccag taatgtgacg aacagacaga gcagcaccac cacgagtatc gccatcaatc
    14821 ttggtaagga tgaccccagt cacttccaac tgagcattaa actcacgcgc aacattggct
    14881 gcttcctgac caatcatagc atcaacgaca agcaagattt catttggttg agccaatgct
    14941 ttcacatcac gaagctcatt catgaggagc tcatcaatct gcaaacgacc cgcagtatca
    15001 atcaagacat agtcgttatg attagtttgg gcttgctcca aaccttgacg tacaatctca
    15061 acagctggta cttctgttcc aagtgcaaag acaggcacat caatctgttg tcccaaggtc
    15121 ttaagctggt caatggcagc tggacgataa atatccgccg caatcatcaa aggacgagca
    15181 ttttcttctt tcttgagttt gttggccaat ttaccagcaa aggttgtttt accagcccct
    15241 tgtaaaccaa ccatcatgat gatggttgga atcttaggtg acttgataat ttctgccgta
    15301 tcagaaccta aaacggctgt cagttcctca tcaacgattt taataatctg ttgcgcagga
    15361 ttaagtgtat caatgacctc atgcccgact gcacgctcac gaactttctt gataaagtcc
    15421 tttacaacag gcaaggcaac gtcggcctcg agcaaggcca agcgaatttc tttggttgcc
    15481 tcttggacat cagattcaga gatttttcct tttttacgta gatttttaaa gacgttctgc
    15541 aaacgttctg ttaaactttc aaatgccatt tttcttcctc ttattctcta ttatcaatgc
    15601 ttgttaaaat ttctatctgc tcctgcagaa agtcatcctt gggatagcgc tccaaaatct
    15661 gatcaaaaat ctgactgcgg acaatatagt ccgagtacat gtgcaatttc atctcataat
    15721 cttccagaat cttttctgtt cgcttgatat tgtcatagac agcctgacga ctgacaccga
    15781 actcctcggc aatttcagca aggctgtaat catcagcgta gtagagctcg atataattca
    15841 tttgcttatc tgtcaaaagc gccgcataaa attcaaagag cgcattcata cgattggttt
    15901 tttcgatttc cataactttt attataccaa aaattagcct aatctaccac actaggaagc
    15961 cgatccaaga agatagatag ctaaatttga aaaagacatg agcctagccc caagtaattt
    16021 ccaattgata gctggcaaag ggatgtccct cttgattttg tagttgataa tctagttcaa
    16081 tcttttgcct atcaacttga taatggctcg tttggatgat aaactcctgc atgcccatag
    16141 gtgtaggaat ataggctaaa ctatcgctat cctttagaaa gcgcataatg gtcttgggat
    16201 tagaaaatcg gctcatcaca agttcttgac catgaaattt aatcactact ttttcctttt
    16261 cctcattata gaaaagcagg tagctataat ctcctttttc atgcacttcc acatcataaa
    16321 gctggtcaat cacttccaac tgctcatcaa actgaattgt atttcgcatc cgaatcttca
    16381 catcaggtcc tctttcttgt ctcttgtcct actattttac caaaaagagc aggattttgc
    16441 tataatggtc atatgaacga aaaagtattc cgtgatccag ttcacaacta catccatgtc
    16501 aataatcaaa tcatctatga cttgattaac acaaaagaat ttcagcgttt gcgccggatc
    16561 aaacaactgg gaacttccag ttataccttc cacggtggag aacacagtcg cttctctcac
    16621 tgtctaggag tctatgagat tgcacgacgt atcacagaaa tttttgaaga aaaatatcct
    16681 gaggaatgga atcctgccga gtctctcttg accatgaccg ctgctctcct acatgacctt
    16741 gggcatggcg cctactccca tacttttgaa catctctttg atacagacca tgaagccatt
    16801 actcaggaga ttattcaaaa tcctgagaca gagattcacc aagtcttgct acaagtagcg
    16861 cccgattttc cagaaaaagt tgccagtgtc atagaccata cctatcctaa taagcaggtc
    16921 gtgcagctca tttctagtca gattgacgca gatcgcatgg actatctctt gcgcgactcc
    16981 tattttacag gagcatccta tggggaattt gacctgactc gcatcctccg agtcattcgt
    17041 cctgtcgaaa atggtatcgc ctttcagcgc aatggcatgc acgccatcga agactacgtc
    17101 ctcagtcgct accagatgta catgcaggtt tatttccacc cagcaacacg cgccatggaa
    17161 gttctcctac agaatcttct caagcgcgcc aaggaactct accctgagga caagaatttc
    17221 tttgcacgaa cttccccaca tctcctgcct ttcttcgaaa aaaatgtgac cttgactgac
    17281 tatctggctc tggatgatgg cgtgatgaat acctacttcc agctttggat gactagtcct
    17341 gacaaaattc ttgcagattt atctcaacgc tttgtcaacc gcaaggtctt taaatccatt
    17401 accttttcac aagaggacca agatcaactt actagcatga gaaaattggt tgaggacatc
    17461 ggctttgatc ccgactacta tactgccatt cataagaact ttgacctccc ttatgatatc
    17521 tatcgtcccg aatctcaaaa tccacggaca cagattgaga ttttacaaaa aaatggagaa
    17581 ctggccgaac tctctagcct gtctcctatc gtccaatccc ttgctggcag tcgccacgga
    17641 gataatcgct tttattttcc aaaagaaatg ttggaccaaa acagcatctt tgcaagcatt
    17701 acccagcaat ttttacactt gattgagaac gatcatttta ccccaaataa aaactagaag
    17761 aggaatttta tgagtattaa actaatcgct gtcgatattg acggaaccct agtcaacagt
    17821 caaaaggaga ttactcctga agtcttttct gccatccaag atgccaaaga agctggtgtc
    17881 aaagtcgtga ttgcaactgg ccgccccatc gcaggtgttg ccaaacttct ggacgacttg
    17941 cagttgagag accaaggtga ctatgtggtg accttcaatg gtgcccttgt ccaagaaact
    18001 gctactggcc atgagattat cagcgaatcc ttgacctatg aggattatct ggatatggaa
    18061 ttcctcagtc gcaagctcgg tgtccacatg catgccatta ccaaggacgg tatctatact
    18121 gcaaatcgca atatcggaac atacactgta cacgaatcaa ccctcgtcag catgcctatc
    18181 ttctaccgta cccctgaaga aatggctggc aaagaaattg ttaaatgtat gtttatcgat
    18241 gaaccagaaa ttctcgatgc tgcgattgaa aaaattccag cagaatttta cgagcgctac
    18301 tccatcaaca aatctgctcc tttctacctc gaactcctta caaagaatgt agacaagggt
    18361 tcagccatta ctcacttggc tgaaaaactc ggattgacca aagatgaaac catggcaatc
    18421 ggtgacgaag aaaatgaccg tgccatgctg gaagtcgttg gaaaccccgt tgtcatggaa
    18481 aatggaaatc cagaaatcaa aaaaatcgcc aaatacatca ctaaaacaaa tgacgaatcc
    18541 ggcgttgccc acgccatccg aacatgggta ctgtaaaagg aaagaataga ctaaaaccgc
    18601 tcagctgagc ggtttttgat gtctaattac tgccccctgc aggaatcgaa cctgcaacta
    18661 ctccttagga gggagttgtt atatccattg aactaaggga gctagataaa aactctgctg
    18721 aaaagcagag ttttttagtc gaattaacga cggatttctt tgatacgagc tgctttacct
    18781 tgaagagcac gcaagtagta caatttcgca cgacgtactt taccgtaacg aacaacttcg
    18841 attttttcaa cacgtggagt gtggattggg aagatacgct caacacctac accgttagag
    18901 attttacgaa ctgtgtagtt ttctgagatt ccagcacctt tacgtgcgat aacaacacct
    18961 tcaaaaatct ggatacgttc acggttacct tcgacaactt tcgcgtgtac acgaacagtg
    19021 tcaccaggac ggaatgatgg gatatctgta cgaagttgac cttcagtcaa gctttggatt
    19081 aatggattca ttttattctc ctatctttgt caatcttgag gaatcttcct cagcggataa
    19141 actgtatttt tgtgcgtcca ttacacacaa gatacagttt accaaatttc taaaaaaaag
    19201 taaagaaatt tatagcaaaa ttcctaaaaa aatcgcaacc aaaccaccta tgtaagtcaa
    19261 agtcaggtaa gaataaaaga ccttcttatc acttagcagt ctttgaagtt cgtcattcaa
    19321 ggtcgaaaaa gttgttaaac cgccacaaaa tcctgttgct agaatagcat atacttcctt
    19381 agactctaca tgattgtaaa atactccaat taaaaaacaa cctaaaagat tagctatgag
    19441 cgttccgagt ggcaatttag aagcttgatt atagcgagaa aataaatagc gcactaaagc
    19501 tccgaaacca caagcaattg caagatagac gattaccatt tcttcctccc tagaaaataa
    19561 gctaagagta ggcctccacc gatgctcaaa agcaaataca ggactaaact aaaataacgc
    19621 cctgtatcaa gcagcttcac agtatcaagc attaggctgg aaaaagttgt taaacctccg
    19681 caaaaacccg tccccagtgc taaaatcaag cccttactag tccccttata gaccagatag
    19741 cccttgacaa gaaaaatcaa gcagaaaatt cccagatagt tgacaaagag agtgccccaa
    19801 ggaaagtctg gactggctgg taaccaggtg gaaactagat atcggacaag tccgcccaac
    19861 atagcagcta gaaaaattcc tagcggataa aattgttctt ttttcatttg atattttgat
    19921 cctgataatc acgcgaacgt ttgagtatgt ccgaaaaagt cgctacaata gtctcctgat
    19981 agcgcttgtc ctctacacga ctcccaacct tttcaaaaat aacttcttct ctcttagtat
    20041 ctaaaatcgg tttacctgaa gctttcttat aagcaaccac cccctcaact aaatgcattc
    20101 gttcttctaa cagtttgaca atttggtcgt cgatttgatc gatttcttga cgaataatat
    20161 ctaaatccat acagtctcct cctttatttg aattattgta tcaaaaagcc atcaattagg
    20221 ctagtaaaat cccaactctc gataagaaaa atgcactgat tgattacatc agcgcacttt
    20281 tatgcttatc ctactttagc aaccaattct tctgcgaatt gttccaagcg ttcaatatct
    20341 tcttcctcgg cagaaagatc aactttaaca cactctgaac ctttttctgc tcctgttgac
    20401 acaaagacac ggtcaaagtc atcaacagcc ttacagaatt catcgtagaa ggtatctcct
    20461 gagccgacca ctccgtagat tttgccattc aagttgagat ctgctaggtc ttcgtagaag
    20521 tccatcatct catctggcaa ttcaccatca ccataagtat aggtcgcaac gatagcgatg
    20581 tctgcttcca agaagtctga agcgtcaaca gttgtacatt catcaacatc aacatccaag
    20641 cccaagtcac gtaatttgtc tgctacaata tctgcaattt cttcggtatt accggtcata
    20701 ctggcaaata caatttttgc taatgccata tcgtcctcct caatttatct ttctccatta
    20761 tatcacatct ttttcatttt aaaaataaaa attcttgtgc tacaatgaaa tgagaaagaa
    20821 ttgaggttat ttatggagat ttgccaacaa attttagaaa aaattaaaga atacgacacc
    20881 attatcattc atcgtcatat gaaaccagac cctgatgcct tgggaagtca ggtgggattg
    20941 aaagccttgc tagaacatca tttcccagaa aaaaccatca aagccgtcgg ttttgatgaa
    21001 ccaactctta cttggatggc tgagatggat cttgttgaag atagagccta ccaaggcgca
    21061 cttgtcatcg tctgtgatac agctaatact gctcgtatcg atgataagcg ctatagtcaa
    21121 ggtgattttc tcattaagat tgaccaccat ccaaatgatg atgtatacgg tgacctgtct
    21181 tgggtcgata ctagttcaag tagcgctagc gagatgatta ccctatttgc ccaaacaacc
    21241 caactagcct tggcagatcg cgatgctgag ttgctctttg caggaattgt cggtgataca
    21301 ggtcgcttcc tctacccttc taccactgca cggactcttc gcctggctgc ttatttgaga
    21361 gaacataact ttgactttgc ggctctcact cgcaaaatgg acactatgag ctacaaaatt
    21421 gctaaactac aaggctacat ctacgaccat ctggaagtgg atgaaaatgg tgctgctcgc
    21481 gttatcctga gtcagaaaat cttgaaacaa tacaatgtaa ccgatgctga aactgcggcc
    21541 attgtaggtg cacctggacg cattgacaga gtgagtctct ggggaatttt tgtcgaacag
    21601 gctgatggcc actaccgagt tcgcttacgc agtaaagtcc atcctatcaa tgaaattgcc
    21661 aaggagcatg atggtggagg ccaccctcta gcaagtggtg ctaattccta tagcctagaa
    21721 gaaaacgaaa tcatctacca aaagttaaaa aacttgctta aaaactgata aaatacttgc
    21781 caaacttttc agaatctgat agactagtat ggtaacaatc tatggctcgc aaagagacca
    21841 tggcagaaag gaaatattgc aaaatgaaaa aagatatcca tccagaatat cgcccagttg
    21901 tcttcatgga cacaactact ggttaccaat tccttagcgg ttcaacaaaa cgctctaacg
    21961 aaacagttga gttcgaaggc gaaacttacc cattgatccg tgtggaaatt tcatcagact
    22021 cacacccatt ctacaccgga cgtcaaaagt tcactcaagc agatggacgc gtggatcgtt
    22081 tcaacaaaaa atacggtctc aaataatgat aagagaacag ttttggctgt tcttttttgt
    22141 ttcttgaaat caactgctgt tttcatgttc cagactcatc tgtaggttcg gtttccatgc
    22201 tactaggcag gaaggaaata gctgtttcaa cacgtccata atgagctgta ctattgtcac
    22261 gaaccacact ttcattgatg gtccaagtgg aattcatttt cttaaaagct tctcggactt
    22321 tttccaaatc tttggaggca atggcctgtt ctaaggtttc aaaacgagga cttagacggt
    22381 ttaccaattt ttccttttcc gcatctaggt caacaggatt ttgttctttt tcaaaagcta
    22441 atagagctga ggaaatttcg gtgagtttgg cttcagtaat atctccagat agagctaact
    22501 tttccttaac aatcttacca acctcagaat ccttattttc tactctttcg aagtctgatg
    22561 ccatcttcgt aacgagtttc tgggtctcag tctgaccacc atttttaacc gttttggatg
    22621 catctgtgat tttcacaaag aaaaaactca agctttcttg ggcacctgct ggggaaagaa
    22681 ttaaaaatga caaagctaaa actagtaacc agcttttagc cttccaataa tttctgacca
    22741 atgtagcctc ctttctccac accaccaaag caagtaaaaa gtccactacc tatgtgagtg
    22801 atgtattcat tcatcttatc agtagcacct aggttagttt gaaccttaac aaagttatca
    22861 ggatccttct ggaaagaaat gaagagcaat cccgtatcaa actgaccagt cttttcatca
    22921 atgccatctg agtaagaata agaacgacgt aaaagtggct tatccacttc tttggccaaa
    22981 caaacatgcg aatcatcagg taagagactc aaatccactt catcaaactc atttttctta
    23041 ccaaaggggg caccgctttc cttgtaacga ccaaaggtat tttcttgttc ttcgagacta
    23101 gtgcggtccc aggtctctaa aaacatctga atccgacgaa ctgccatata agaaccattt
    23161 tccatccagt ccttactatc agcccagata acgcggtcaa agtcttgctc cttggttgga
    23221 tttgctgttc catccttaaa accaaagagg ttccacggag tctccattcg atccccgata
    23281 gctgcaaatc cagactgact ccaacgaagg ggcaccgcat ttctcccctt acggatgaga
    23341 ttgcgaatag cgtgaaaggc aatttgctca tcatctgcac aagcatgaat cacaatatct
    23401 ccaccagtat atttttcacg taattgctcc ttaggaaata gaggtaaatc cctgaacagt
    23461 cgagggcgct tgttttccaa gttcatcctt ttcaagaaac ttgcagatac accaaaagtc
    23521 agcgtcaaac gatgaggatt gagcccaact gtctcaccag tatcgctcgg aggaaagaga
    23581 gcattctgtc catctttttt aaccaattcc ccctcgacca acttggcact ataatccgtc
    23641 caatccttga atagctggat aattttatct ctatccgtcg tatgcaggtc caagacaaca
    23701 aaatagatat tcttttgcat gggcgtacta tttggtacat caagcgaacc ttatgaaaag
    23761 gtctactggt tttaaagcgc tttcttgtct tcttgaattg agattttatt tttagacgcg
    23821 acaatggttt gagcgtctgc tttcctagga tgttctggac gtggtgtaat atttcgccaa
    23881 ccatggcgct tcaacagttg atagaaggca tcacgtgtgt aggaacgacc taactccttt
    23941 ttataagcct gaaataaggc atcaattgta acaaattctc ctgcctctgt agccttcaaa
    24001 tgacgggcaa gaaaggcttt ctcttcctca actgtcatat atgcatggtt acgaccacca
    24061 cgtgtttctt gaaggagaga gtcgagtccg aactcctcat atttttttac atttcgctaa
    24121 atcgttgttt gattacagtc
//
LOCUS       DAVLCS010000029        23336 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLCS010000029 DAVLCS010000000
VERSION     DAVLCS010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.029"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            160..747
                     /locus_tag="VXC78_001408"
     CDS             160..747
                     /locus_tag="VXC78_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV0583470.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            674..2317
                     /locus_tag="VXC78_001409"
     CDS             674..2317
                     /locus_tag="VXC78_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0583471.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2328..3689
                     /locus_tag="VXC78_001410"
     CDS             2328..3689
                     /locus_tag="VXC78_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV0583472.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            3746..3874
                     /gene="blpC"
                     /locus_tag="VXC78_001411"
     CDS             3746..3874
                     /gene="blpC"
                     /locus_tag="VXC78_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV0583473.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(3945..5285)
                     /locus_tag="VXC78_001412"
     CDS             complement(3945..5285)
                     /locus_tag="VXC78_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0583474.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(5299..6036)
                     /locus_tag="VXC78_001413"
                     /pseudo
     CDS             complement(5299..6036)
                     /locus_tag="VXC78_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(6041..6379)
                     /locus_tag="VXC78_001414"
     CDS             complement(6041..6379)
                     /locus_tag="VXC78_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0583475.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            6655..6984
                     /locus_tag="VXC78_001415"
     CDS             6655..6984
                     /locus_tag="VXC78_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0583476.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7152..8201)
                     /locus_tag="VXC78_001416"
     CDS             complement(7152..8201)
                     /locus_tag="VXC78_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0583477.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8198..8929)
                     /locus_tag="VXC78_001417"
     CDS             complement(8198..8929)
                     /locus_tag="VXC78_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583478.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVADPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            8997..9407
                     /locus_tag="VXC78_001418"
     CDS             8997..9407
                     /locus_tag="VXC78_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0583479.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9417..9704
                     /locus_tag="VXC78_001419"
     CDS             9417..9704
                     /locus_tag="VXC78_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583480.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            9866..10060
                     /locus_tag="VXC78_001420"
     CDS             9866..10060
                     /locus_tag="VXC78_001420"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583481.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSNHTHD
                     KPTLTWFEEIFEEYHSPFHN"
     gene            complement(10394..11530)
                     /gene="dnaJ"
                     /locus_tag="VXC78_001421"
     CDS             complement(10394..11530)
                     /gene="dnaJ"
                     /locus_tag="VXC78_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV0583482.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(11932..12288)
                     /locus_tag="VXC78_001422"
     CDS             complement(11932..12288)
                     /locus_tag="VXC78_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV0583483.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(12290..14113)
                     /gene="dnaK"
                     /locus_tag="VXC78_001423"
     CDS             complement(12290..14113)
                     /gene="dnaK"
                     /locus_tag="VXC78_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV0583484.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14593..15117)
                     /gene="grpE"
                     /locus_tag="VXC78_001424"
     CDS             complement(14593..15117)
                     /gene="grpE"
                     /locus_tag="VXC78_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV0583485.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15144..16178)
                     /gene="hrcA"
                     /locus_tag="VXC78_001425"
     CDS             complement(15144..16178)
                     /gene="hrcA"
                     /locus_tag="VXC78_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV0583486.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKTLQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVHLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16346..16852)
                     /locus_tag="VXC78_001426"
     CDS             complement(16346..16852)
                     /locus_tag="VXC78_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV0583487.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCMSLFREDLSMSFFLIFCFICFSDFLSNSWLFQ
                     TKKEIPSR"
     gene            17460..19793
                     /locus_tag="VXC78_001427"
     CDS             17460..19793
                     /locus_tag="VXC78_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0583488.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            19806..21269
                     /locus_tag="VXC78_001428"
     CDS             19806..21269
                     /locus_tag="VXC78_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0583489.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21269..22837
                     /locus_tag="VXC78_001429"
     CDS             21269..22837
                     /locus_tag="VXC78_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0583490.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYGNKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTEIPWVSISDMP
                     ISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATHNEAIISIF
                     PYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNHEEMKRIIF
                     KVDLLFQKVSQLFE"
     gene            complement(22791..>23336)
                     /locus_tag="VXC78_001430"
     CDS             complement(22791..>23336)
                     /locus_tag="VXC78_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0583491.1"
                     /translation="IPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKP
                     LEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVATSLEHIGKFARIDKDYDGVVAGGF
                     IFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAP
                     FEEQELITQKVEKLFEKVNQL"
BASE COUNT         7511 a         4659 c         4273 g         6893 t
ORIGIN      
        1 aggtttttta tttcaagcca cctctaaatg tttaaaaaaa ataatttcta atcacttttt
       61 taccattcag gaagttttaa tgactattca agatttcata aaatatgaac ttagttttat
      121 gacataatag acctatccac tatatgaaag gaattgccaa tgacttctta taaacgtaca
      181 tttgttcctc aaatagatgc gagagactgt ggtgtcgctg ccttagcctc gattgctaaa
      241 ttctatggtt cagatttttc tctagctcac ttgagagaac ttgcaaagac caataaagaa
      301 gggacgactg ctcttggcat tgtaaaagcc gctgatgaaa tgggctttga aacaagacct
      361 gttcaagcag ataaaacgct ctttgacatg agtgatgtcc cctatccatt tatcgttcac
      421 gttaacaaag aaggaaaact ccaacattac tatgttgtct atcaaacaaa gaaagactat
      481 ctgattattg gtgatcctga cccttctgta aaaatcacta aaatgtcaaa agaacgcttt
      541 ttctatgaat ggactggagt agctattttt ctagctacca aacccagcta tcaaccccat
      601 aaagataaaa agaatggtct actaagcaag cttccttcct ctgattttca aacaaaaatc
      661 tctcattgct tacattgttc tctcaagctt attggtcact attatcaata taggtggttc
      721 ttactatctc caaggaatct tggatgaata cattccaaat cagatgaaat caactttagg
      781 aatcatctca gttggtctgg ttatcaccta tatcctccaa caagtcatga gcttctccag
      841 agattatctc ctaaccgttc tgagtcagag attaagtatt gatgtgattt tatcctatat
      901 tcgccatatt tttgaacttc ccatgtcttt ctttgcgaca cgtcgtacag gagaaatcat
      961 ttcacgattc acagatgcta actctattat agatgccttg gcttctacca ttctttctct
     1021 ttttctggat gtttctattc tgattcttgt aggaggcgtc ttactggcac aaaaccctaa
     1081 tctcttcctt ctttctctta tttccattcc tatatacatg ttcatcatct tttcttttat
     1141 gaaacctttc gaaaaaatga accatgatgt catgcaaagt aattctatgg ttagctctgc
     1201 cattatcgaa gatatcaacg ggattgaaac tataaagtcg ctcacgagtg aagaaaatcg
     1261 ctatcaaaat atagacagcg aatttgtaga ttatttggaa aaatccttta agctcagtaa
     1321 atattctatt ttacaaacga gtttaaagca gggaacaaaa ttagttctga atatccttat
     1381 cctatggttt ggcgctcaat tagtcatgtc gagtaaaatt tctatcggtc agctgattac
     1441 ctttaacaca cttttttctt actttacaac tcctatggaa aatattatca acctccaaac
     1501 caaactccaa tctgcgaagg tcgctaataa ccgtttgaac gaagtctatc tagtcgaatc
     1561 tgaatttcaa gttcaagaaa accctgtcca ttcacatttt ttgatgggcg atattgaatt
     1621 tgatgacctt tcttataagt atggttttgg acgagatacc ttaacagata ttaatctcac
     1681 gattaaacaa ggagataagg ttagcctagt tggagttagt ggttctggta aaacaacttt
     1741 agccaaaatg attgtcaatt tctttgaacc ctacaaagga catatttcta tcaatcatca
     1801 ggatattaaa aacattgata aaaaagtctt gcgccgtcat attaattacc taccacaaca
     1861 agcctatatc tttaatggct ctatcttgga aaacttaact ttgggcggta atcatatgat
     1921 tagccaagaa gatattctaa gagcttgtga attagctgaa attcgtcaag acattgaaag
     1981 aatgcctatg ggctatcaaa ctcagctctc tgatggagct ggtctatcag gaggacaaaa
     2041 gcaacgaata gccctcgctc gtgctctttt aactaaagct cctgttttaa tactagacga
     2101 agctactagc ggtcttgatg tcttgactga gaaaaaggtt atagataatc ttatgtctct
     2161 aactgataaa accattctct ttgtagccca tcgtctcagt atagccgaac gaaccaaccg
     2221 tgtcattgtt cttgaccagg ggaaaatcat tgaagttggt agtcaccaag agttaatgca
     2281 ggcgcaaggt ttctaccatc atctattcaa taaataagga gaatgtcatg aatcctaatc
     2341 tttttagaag cgtcgagttt tatcagagac gttaccataa ctatgcgaca gtgttcatta
     2401 tacctctttc attactattt actttcatct tgattttctc ccttgttgcc acaaaagaaa
     2461 ttactgttac ttcccaagga gaaatcgccc ctacaagtgt cattgcctcc attcagtcaa
     2521 ccagtgataa tcctatccta gctaatcatt tagtggcaaa tcaagtagtt gaaaaagggg
     2581 acttactcat caaatactct gaaacaatgg aagaaagtca gaaaactgcc ttagcaactc
     2641 aattacaaag acttgagaag caaaaagaag gacttggaat tttgaaacaa agcttagaaa
     2701 aagcgactga tcttttttct ggcgaggatg aatttggcta ccataatacc tttatgaatt
     2761 ttactaaaca atcccatgat attgaactgg gtatcacaaa gactaacacc gaagtttcaa
     2821 atcaagctaa tctttccaat agcagttcat cagctattga acaagaaatt acaaaagttc
     2881 aacaacaaat tggagaatat caagagttga gagatgctat cataaataac agagcacgct
     2941 taccaactgg caatccgcac cagtcaattt tgaatcgtta tcttgtagcc tcacaaggac
     3001 aaacacaagg aactgcagag gagccatttt tatctcaaat taatcaaagt attgcaggtc
     3061 ttgaatcatc tatcgcaagc ctcaaaattc agcaagctgg tatcggaagt gtagcaactt
     3121 atgataacag tttagcaacc aaaattgaag tactccgcac tcagttttta cagacagcct
     3181 cacagcaaca actaactgtg gagaatcaat taacagaatt aaaagtacaa ctagatcaag
     3241 ccacacagcg tttggaaaac aataccttaa cctccccaag taaaggtatc gttcatctga
     3301 acagcgaatt tgaaggtaaa aatagaattc caactggtac agaaattgct caaatattcc
     3361 ctgtcatcac agatacaaga gaagtactaa tcacttacta cgtatcttct gactatctac
     3421 ctctactaga taaaggacaa actgtaagat taaaactgga gaagattgga aatcacggca
     3481 ccaccatcat cggccaactt cagacaattg atcaaactcc taccagaaca gagcaaggaa
     3541 atctctttaa attaaccgct cttgcaaaac tatctaacga ggatagtaaa ctcatccaat
     3601 atggcttaca aggtcgcgtc actagtgtaa ctacaaagaa aacatatttt gattatttca
     3661 aagataaaat tttaacccat tctgattaat tttcagataa cactctataa ctatttatta
     3721 tcttatcaaa aaggagaatc ataacatgga taagaaacaa aacctaactt catttcaaga
     3781 actaacaact accgaactca accaaattac aggtggagga ttgtgggaag atttattata
     3841 taacattaat agatatgctc attacatcac ataagaactt catcatccaa tacaactata
     3901 aaaaaataag accgagaaac aagtactctc ggtcttattt ttcatcattc tgtatgtatc
     3961 acagtaagta cctgacgaaa gacttgattt tgacaggtgg tatttagact ggtattagga
     4021 tggctttcca caatcttcat gacggtatag agaccaactc ctctctcctc ccctttagaa
     4081 ctggctccaa aggagaagat ttcagaaata tcgatgccct cttctttgat ggagttttcg
     4141 atgataaagg tctcctgtgc tccatttttt aaaaaggcga ttgaaacatg aggttgacta
     4201 gcttccacac tggcttcaat agcattgtca caaaggatag acacaatggt tagaaaatca
     4261 agtagactca tcccctcgac ctgaatctcc tcaggaactt cgacattaaa gacaatgttc
     4321 ttatctctgg cttttaaaaa tttccctgct agaagacttt tgagggcttt atcacgaata
     4381 tttaccaatc tgcccaggtc atatttattg ttctgcaatt tctgactgga atcctttaag
     4441 acggagccat agacctcttt tatctgctcc atatcctcct cttcaatgcc cagacgtaag
     4501 ctagtcaaga ggttggtata atcatgacga aagctccgta cttccttgta aagctcctct
     4561 atatgccgac tatagcgttc catatctcta tagcgcaggg cctgctcttg ttccaatctc
     4621 tcatagagtt tttccttcaa ataggtatcc aatttcttga taacccccat aaaaaagagt
     4681 aggtaaaaga ctaggatgag atggcgaaca gtctttgatt gaatactttg ttcatattca
     4741 aaaaaagaca gactttccat gactagatag tagccaccca ttatccagtt aatctgagtc
     4801 agggactttt gaaaggcttt atcgagaatc tcctttctca agctagtaaa atcgtagtcc
     4861 aaccatttca aaaaagctag agaaatgaag aaattgaaaa ttattataca taacccagta
     4921 aatgagtagc catcatatac ttgcccttgt cccaaaaatg gaagcacaaa ataggagact
     4981 cctctataaa agagattcac caatatcatt ggaaagagac cataaaagaa aaggagtttt
     5041 ttaggaagcc ctctcaataa taagaaagat aagcctatgc cgtacaaggg ttccataaaa
     5101 taagataggt aaacatttcc tactatatag ctaatcatca caaaaacaaa ggccaacagt
     5161 atcttaaaaa gaaaggcctt aaaaatcctc tcgaaagtaa gatcaattcc atccacctta
     5221 aagaagatga caatttctag tccattagta acaagtgtat acaacaatat ccaagcaatg
     5281 ttcataaatt ctcctagctc agtgtaattt attgatggcc tcagacactt ccctgacctt
     5341 ataacgggcg attagacaac ttccaccatt gggaaagaaa agcagttttt ctttcttatc
     5401 caaatgcacc acatttgcag gattgatgag aaaagagcgg tggcactgca agagacgggg
     5461 ctcctgcttg aaaacctcct ctaaactcgc tgtaaattcc agcctgtctg tcttggtata
     5521 gagaataaca cgatgggctc tgggcgacgt ttcgagatag taaacctctt taaaaggata
     5581 ctgaaattgg gcaaattttg atttaaagta aaagcaatct tccgccagac ttttactatc
     5641 ttgactattg gcatagagga gggctgtctc gatccgagat tcaaactcct ctgctgacaa
     5701 ggccttatca atgtagtcca aagcagacac ttggtagcga aaagacaggg gcataaactc
     5761 cgagtgagtc gtcacaaaga caatcagggc ataaggatcc cgatcccgaa tctttctagc
     5821 cacttccagt cccttcatct cttcatttcg aatctcaata tccaaaaaga atagctgatg
     5881 ggcccccttc tcatgcactt cagccagcag ttggtccggc ttgccaaata cctcaaaaga
     5941 gctaggaatg atatgatgtg ctttcaaaag tttctcaatc gtcgtttcaa ttctagtcta
     6001 ttgggaaaaa tcatcctcta aaacaaatat tctcatcttc ttactctccc tctttcaacc
     6061 atttttgacg aatttctcta tagcgacgtc tggcatactt gacagcgtat tgaccttctt
     6121 ctccgagaaa aaggattctt tcttgaaaat caatcgattt taatttatca agattaacca
     6181 aacaatttcg atgacatctc atcaaggttt ccccacattg gttctcaaga ttacttaaat
     6241 tttgaagcat attaaaacta gcttcttctg taacaatctg tacggtatgg gctttagttg
     6301 gatgtgtttg gatatagtag atatcgtcga tgtttacttt atagactgtt ttctgcgtct
     6361 gaataatcat atatttcatt ggattctcct cctaagaaaa gaataacaga aaaggtctag
     6421 cccaagcaca cccaatccta aacagtcttt gaaaactcct aaaaggatta ttttctacaa
     6481 catcatgatg agcttacaac tattttatca taaaattcac tcagcgcaat tcaagacatt
     6541 tcaatgacaa ttaaagattt gaataaaaaa aaagaattaa aagtgataaa ctaacagtat
     6601 caaaacacag ttgccagaag taagactggc acccagatta aaggaggcat tcccatgaca
     6661 gatacagacc ccatcaaaag agctcatact ttgattactg acttaaacaa agcctaccaa
     6721 gcatgcaaac aggcaagcgc tgacgacgtc cgctttcagg agcaattaaa ctctattctt
     6781 ggttttctag ccaaggctga aacagtggat aatcgattct tgattgaact agaaaaattt
     6841 taccagactt ccagtcttct catgggactc agcgctcttg atccagatgc tccaactcgc
     6901 gccgcttggc gggcctatga ccgcttccac tttgaccaag tcaagaccaa gttaatactc
     6961 aatgaaaatc aaagagcaaa ctaggaagct agccgcaagc tgtacttgag tacggtaaga
     7021 cgacgctgac gtggtttgaa gagattttcg aagagtataa gtctctacgg accaaccatt
     7081 atcctgtagt aacaaaaaag aagttgagac agactgaact caacttcttt tttagtgtcg
     7141 tatcagcaat gttagtcctg catctgacgt tttacctgat aaggcaaata caagactagt
     7201 aaaaccaaac cagctcctag taaggctaga agggctagtt tttcttggaa ggtaatcaac
     7261 ccaacaacta attccacaag taaaacaaaa ctggtcaatc ctcgaactac ctcctgtaag
     7321 cctttttcct tttgcccctt gtccagcgga aagagttggg tcaaatactg gtagtcaaag
     7381 gcatgataga gggccagcaa ctggaagagc aagaggtagt taaagagaac taccactgct
     7441 gtcgcaatcc aagcttgctc gataaaaacc tgcgccagta cggaaagtaa gagaagacga
     7501 agactgagag caaagaggtc gccatttcgc agataagaac gcagatagag attttgccaa
     7561 atcttcccag gcaccttctg aacagccttt aagataaagt ccagataggc acgacgctta
     7621 acgctgtttg aaattccctt gacctgcgta aagagggcaa agaaacgaag caagacttgc
     7681 ttacgcttgc tttcttggga aatgacatag tcccaatcca gtccagtttc agtgaaaaat
     7741 ttgctggcct tttgacgaaa gtggaaatat tttcctaccc ccaataaaag cacatagagc
     7801 agaaaaactg gcaagccata acccattgct aaaaataaag gcgcaaataa cagcaagaaa
     7861 agggtctgta caaagagcca aaagactagg gaaatgccag tttgacgctt gagatggagc
     7921 ttgatttcct cttctccaac taagagaaag agcttgtctg gagcctccat ataggtggca
     7981 attcctcccc aaagtaaaag taaaacagac gtaattccta caaacaaaag gataggccaa
     8041 tgattttcag gaaaatgttg taagagttga ctgtactggt aggctagaaa gcccaacagg
     8101 acaagcagga acaagacaaa gtggtcattg agcacatagc gcagataacc aagacactcc
     8161 ttacgaaagg cctgctttct ctttaaaaac aagtctttca taggtcctcc tcttttgtca
     8221 gagccaagta aatatcattc aaactagcct caggcatatc aaaggcttcg cgtagttgca
     8281 ggagattgcc tttggcacgc acctctccct tgtgaagaat gacaaaggca tcacacatct
     8341 tctccgccga atccagcacg tgggtactca tgagaataga cttgcccttt tgcttctcca
     8401 cttccaaaag ctgaatcaaa tcagaaatag ccagcggatc aagaccaagg aaaggctcat
     8461 ccacgatgaa aagacttgga tccgccacaa aagcacagat aatcatgacc ttctgcttca
     8521 tcccttttga aaaatgaaca gggaaccagt ctaatttctg ttccaaacgg aacattttta
     8581 acaagggctc tactcgttcg aaagccactt tttgctcaat accgtaagcc atagcaaccg
     8641 tttcgatatg ctctctgagg gtcaattcct catacagact aggcgtctca ggaatgtagc
     8701 caatctgctt gcggtagcta gtcgcatctc cttgcagagt caggccattg atattgatgg
     8761 agccactata aggtgccaac agaccgataa tctcattgat cgtcgttgat ttcccagcac
     8821 cattgagacc aatcaaaccg accaactgcc cactttcaac agtaaaggac acatctttca
     8881 aaacaggaac atgaacatag ccacctgtca ggtttttaat ttctaacata ttttctccaa
     8941 atctggtata atgtagctat attatatcaa aattcagtac agtagaggta gattttatgt
     9001 cagattgcat tttttgtaaa atcatcgcag gggaaattcc tgcttcaaaa gtatatgaag
     9061 atgagcaggt ccttgccttt cttgatatct ctcaagtaac actaggacac accttggtcg
     9121 tgccaaaaga acactatcgc aatcttttgg agatggatgc tacgagcgcc agccaactct
     9181 ttgcccaagt accaaaagta gctcaaaaag tcatgaaagt cactaaggct gctggtatga
     9241 atatcatttc caactgtgaa gaagtcgctg gtcaaacagt ttttcatact cacgttcacc
     9301 ttgtacctcg ctacagtgct gacgatgacc tcaagattga ttttatcgcc cacgaaccag
     9361 actttgacaa acttgctcaa gtcgctgaaa ccatcaaaaa cgcttaagga gttgctatga
     9421 aattatccaa cctactgcta tttgcaggag ctgcagccgg aagttatctg gtcacaaaaa
     9481 atcgccaaac catcacagat gaagtcttga ataccactga ccgcgttcaa gctatcaagg
     9541 acgatgtgga tattatccaa aacagcctgc aaatcattga ccagcaaaaa gaacttatca
     9601 aggaatacca agaagacttg acttacaagt ttaaggtctt ggaaaaggat atccagacta
     9661 gactagctgt gataaaagaa atgcagggaa ctgaagataa gtaaaaagag cccgacggct
     9721 cttttttaaa acgtaaacaa gttatagtga attgaattta gaatagcaca tcatagtttc
     9781 taaagcattg ttagagatta ctttaaaatc ctcttatcaa tttgttcata ttctatttca
     9841 atctactata tatatcccat caactatgca tcataattta ggtaactcat actcaataaa
     9901 aatcaaaaag caaactagaa agctaggcac agactgctca aaacaccgtt ttaaggttgt
     9961 ggatagaact gacgaagtca gtaaccatac ccatgacaag ccgacgctga cgtggtttga
    10021 agaaattttt gaagagtatc attcaccatt tcacaactaa atcgaagact ttctgccgta
    10081 atgaaaacac ctgaaacagc ttggtttcgg ctatccggaa actttaagac ttaggttcaa
    10141 agtttaggta tggaacttcg aaggaggtcg ctaccgtccg tcattactta ggaaagtctt
    10201 aaaaaatcta taaagtaaaa agagcccgac agctcttttt gtttatactc aatgaaaatc
    10261 aaaaagcaaa ctaggaaact agccacgggc tgctcaaaac actgttttga ggttgtagat
    10321 acgactgacg aagtcagtca catatatacg gcaaggcaac gctgacgtgg tttgaagaga
    10381 ttttcgaaga gtattattct ccatcaaagg catctttaat atggtcaaag aagccttttt
    10441 tctttggatt tactttcaag tcaccagcag ccgcgaattc tttcaaggct actttttggc
    10501 ggtcgttcaa gcctgtcggt gttacgacat taacagtaac gtattggtca ccaactgcac
    10561 cgccacgaag gctcggtgcc cccttactac gtaggcggaa cttcttacca gtctgagttc
    10621 cctctggaat aaccaattca acatcaccgt gaacagttgg aatatctact gtatcaccaa
    10681 gagccgcttg gacaaagttg aggttgagat tgtagaagat agtcgttcct tcacgttcaa
    10741 acttgtcgct agcttccaca gaaactacta catacaagtc accataaggt ccaccgttaa
    10801 agcctgcttc accttgacca gcgaggcgaa tttgttgacc tgtttccaca ccagcaggga
    10861 ttttcacatg tacgctatga gcttgtttct catgacctgt tccatgacag gttgtacatg
    10921 gatatttgat ttcttttcct cgaccgtgac agacatcaca ggttacttgg cgacgcatca
    10981 taccaagagg agtctgcgta tcgacgttaa tgacaccagc gccatgacag cgtccacaag
    11041 tgactggact tgtccctggc ttagcaccag atccattaca tgtacgacag ccagcttcac
    11101 gatgatactt aacttccttc tcagttccga agatagcttc ttcaaaggtc aaattgacac
    11161 gatactggag atcatctcct tggcgaggag cgtttggatt gcgcgaagaa ccgcctccgc
    11221 cgaagaaact tgagaaaata tcctcaaaac caccgaagcc acctgcccca ttgaaaccgc
    11281 cgaaaccacc agctccacca aaaccaccat tggcgcctgc agcaccatac tggtcatagg
    11341 cagcacgttt ttggtcgtca ctcaaagtct cataggcttc ttgaacttcc ttgtacttgt
    11401 cctcagcacc aggctccttg ttgatatctg ggtgatattt tttggaaagc ttacgataag
    11461 cctttttgat ttcgtctgcc gaagcgtttt tggatacccc cagacgatca taaaattcag
    11521 tattgttcat aattcaagat acaaagggcg tcaaacggac acagccatct aggagttttg
    11581 acgacggacg cttacgtcct agaaaaaact atctttttgg cacagtccat agcccgtgtt
    11641 cagttacgaa cacccttatt cctttctatt gatgttctga atcgaaccac catttaggtc
    11701 gggttcaatt cctttctttt atatttagta agaaattctg aaacccgtgt tcagttacga
    11761 acactctttg ttcctttcta ttgatgagac aaaacccaaa caaatgagat tccgtccctt
    11821 tttatcgaaa aacagaggct gggttgcaac ctctgcaaat aagtaaatta actttatttt
    11881 gattttaaat atcctataag tacagaaata tttatatatt tttgtctctt cttagtattt
    11941 gcctatataa ttccaattga tcataagaaa tacaactact gtccaaatca taccaattat
    12001 gaacggtatt acaaatttat atgtttgtat ttctaatgat atcatagctg ataccatcgc
    12061 tgatacaaat gcagacaaca atactgaagt aacaaaattc cttaccgctt catcattttt
    12121 gacacaacta tcatgctcag ctaatataat ttctctatat atagtcaaac attctactgg
    12181 aatattatct ataaaacctt ttgctgcttc atagttgtca gcttgattac aaaaatcatt
    12241 ataaactttt cgtgtatttt ttagatactc atcatccaat acactcatct tatttttccg
    12301 taaactctcc gtctacgacg tcatcgcctg cgtttcctgt tgcttgtgcg ccttctgctc
    12361 cttcttgagc ttgttgcgct gctgcggctt gttcgtagag tttcacagca aggccttgag
    12421 ctttttcgtt caacgcttca agtttcgctt tcatgtcgtc caagttgttg tcttcttgag
    12481 ctttcttaag gtcatcaagg gcagcttggg cagcgtcacg ttctgcgtcg aagcctttac
    12541 cttcagtttc cttgattgtc ttttcagtcg caaagattgc ttggtctact tcattacgaa
    12601 ggtctacttc ttctttacgt ttcttatcgg cttcagcgtt tgcttctgca tctttcatca
    12661 tgcggtcgat ttcttcgtca gtcaaacctg agttcgattg gatgacaata gtttgttctt
    12721 tttgagttcc aaggtctttg gccttaacag acacgatacc gttcttgtcg atgtcaaatg
    12781 ttacttcgat ttgaggaatt ccacgaggtg cagctgggat atcagtcaat tggaagcgtc
    12841 caagagtctt gttatctgct gccattgggc gttcaccttg aagaacgtgg atatcaacgg
    12901 ctggttggtt gtctgctgct gttgagaaga cttgtgattt agatgttggg attgtagtgt
    12961 tgcgatcgat aagttttgta aatactccac ccattgtttc gataccaagt gacaatggcg
    13021 ttacatcaag aaggacaacg tccttgacat caccagtaat cacaccacct tggatagccg
    13081 cacccatagc aactacttca tcagggttta ctgatttgtt tggttcttta ccagtttcag
    13141 ctttaacagc ttcaacaacg gcagggatac gagttgaacc accaacaagg ataacttcgt
    13201 caatttctga caagctcaaa cctgcatctg aaagggcttg acgaactgga acttttgtac
    13261 gttcaacaag gtcacgagtc aaatcgtcaa atttcgcacg agtcaaagtc atttccaagt
    13321 gaagaggtcc agcctcacct gcagtgataa atggcaagct gatttgtgtt gaagttacac
    13381 cagaaaggtc tttcttcgct ttttcagccg catctttcaa acgttgcatt gccatcttgt
    13441 cagtagacaa gtcgataccg ttttctttct tgaattctgc taccaagtgg tcaatgattt
    13501 tttggtcaaa gtcgtcacca ccaagtttgt tgtcccctgc agttgacaat acgtcgaaga
    13561 caccgtcacc caattcaagg atagagacgt cgaatgtacc accaccaagg tcaaatacca
    13621 agattttttc ttctttgtca gtcttgtcca aaccataagc aagagctgct gcagttggtt
    13681 cgttaacaat acgttctact tcaagaccag caattttacc agcgtctttt gttgcttgac
    13741 gttgagcgtc gttgaagtaa gccggaactg tgataacagc tttggttact ttctcaccaa
    13801 ggtagtcttc agcgtagcct ttcaagtatt gaaggatcat agctgagatt tcttgtggag
    13861 tgtattcttt tccatttgca gaaacttttt cagaagttcc catcttagat ttgatagaga
    13921 taactgtatc tgggtttgtg actgcttgac gttttgcagc atcaccaacg atgatttctc
    13981 cgtttttgaa tgagactaca gatggagttg tgcggttccc ttctgggttt gcgatgattt
    14041 tgctttcagt tccttcaaga actgcaactg ctgagtttgt tgtacctaag tcaataccga
    14101 taattttaga catgtgtttt tctccttgtt agttaatttt ctatttttct ttttgatact
    14161 cttcttaagt ggcgacgccg tcagagcttg acttcgtcaa tctctttgac taaactttga
    14221 gcctaaggtc tcaaaatttg cgcaaatagc accacggcga agagtatcgt ctttggttcg
    14281 cttcgctcac tattacaaag ccaaacatat tttatctttc ttcatagttt attgtcgttt
    14341 cggacaagtt ttctattatg taaattgcga cacgaggagt cgaaatcgat tttatttcga
    14401 cgacgagtta gtaaggaagc taggcaaacg tcatagcgat tgccgttttc tgacgagttg
    14461 ctttagctac cgtcagaatt gccgaatcga acacgcccta agctctgagt aaaaaagata
    14521 gattttcttg tgttcatcga acacttcgtc aatctcctat ttttactgcg agctttttac
    14581 gagctttgta tcttagttat acaccactac cattgctggg cgtaggatgc ggtcatggag
    14641 tttgtagcct ttttgaaaga cttgggcgat ggtatctact gggtgttcat cgtctgctgg
    14701 gagagtttgg atggccatat ggtagttatg gtcaaattcg ccatctgctg cgatttcttc
    14761 aattccttct tctttcaaag cgtgaatcaa gctttcttgc accatcgcca agcccttctt
    14821 cacatcatct gtcaaacctt caactgcaag tgcacgctca aggttgtcaa gagatggtaa
    14881 gattgctttt gccaagtcct ggctacgata acgttgcaag ttttgacgtt cttcattggc
    14941 acggcgttgg atattttgca tttctgcatg agcgcgaaga tatttgtttt cgaactcatc
    15001 tgcacgttca tttgccaagt ccaactcaga cttttcagga gttgtttctt cagctgtttc
    15061 cacaacttcc tcttcttgaa cttcttctac ttcttcattt tttatatctt gggccatgtt
    15121 cgcctccttt aatgatttca atcttaatgt acttcgtaat gattactgct gaggtagcgg
    15181 taaaaatctg tcaacttcat ggtcaaaaca cggttgacca cattgacttg attgattagc
    15241 tgttggtaat ccagattaac tggaccgata atggctagaa ttccaactcc ccgataagga
    15301 atgaggaact tactactaat caccgctagg tcagctaaac aggactcttg accgtctgca
    15361 acacgaacat tttgcatctg atcctcacgc aacccctcac gaatctccaa ggccaccttt
    15421 tgcggttggt caaagaactg ataggctgct agattggcaa aattcaagag atggaccttg
    15481 cccgccatca caatgttttc gttgaacatt tccttaaaga tgtgttcaaa gagatcgatg
    15541 acattatccg ttgttgtaaa gtaacgctgg ataatctgcg gaatctccgt ccgaatcttg
    15601 tagtgaatat ctaaaacggt gtgaccgagg aaacgttcct gaatgatgct cttcagtttc
    15661 agcaaatcct cctgcaagaa gttccttgga atcagaaact gactagtaac cgttcgcgac
    15721 tcgtctaggg taaataccgc caaggctgta tgttgcccca aaacaacgat atcaaaggct
    15781 gtcaaacgtt gcctgctcgg ctcaacatcc agtgccacta ccgtacagcc actcaggtct
    15841 gttagcaagt tagcagcctc ttgcagaata tcctccaatt tgaagaattc ctgatcaaag
    15901 gctttgacaa tctcatatac ctcattttca gccagtcggt caaaatccag tgagtgtttc
    15961 acatagtact gaaaaccagc aacacttggc atccgaccgc ttgaagtatg agccttctca
    16021 agcaaccctt gtttttctag ttccgccatg tcattacgaa tggttgcact gctagagtta
    16081 atagactctt gcaaggtttt tgatccgaca ggttcgtgcg ttttggtaaa gatgtcaata
    16141 atcagattta aaatatcctg ctgacgctct gtaaccatct catcactcct ctctgtctga
    16201 tcaattagca ctcaatgcat ccaagtgcta actcatgatt ctattataca cccttagaag
    16261 agaatgtcaa gacaaaaact caaaaaatta gcactctttt atcaagagtg ctaaaaatca
    16321 atctgaagac ctagaacctt gctattcatc tactcggtat ttccttttta gtctgaaata
    16381 accatgaatt agataagaaa tcagaaaagc atataaaaca aaaaataaga aagaaagaca
    16441 tagaaagatc ctctctaaac aaactcatac aaacaacaag accacctaag aaagtagctg
    16501 tacaggaacg aagtctagat cgcataactt cccatttgag ccccttactc atatagactt
    16561 gatcctctgg aagtaaatca gaagacgatt tacgaagaat cgaacaagaa cctgctccta
    16621 tcaattccca acctctatct ctaaaatctt gcagttcacg cttatgctct ttaagaaatc
    16681 tagaatcata gatacgatag ataacatcgt ccggttgacc ttgctcaaaa tagaacaaac
    16741 caaaacgact cgttctatac ctccaacctt tcaaatgcat ctcatgtaaa tattcttctt
    16801 tcttgtccaa atcaacaatg gtgaaaatcc gaaattctac tctgctattc attgtcttac
    16861 cccaaaatta gaaaacatgc ctggcgttat ttattagata attctttcca cttttgactc
    16921 aatctccaaa aaatataaga aatctgaatc gcaaaaacta tcaataaaac ccaatctatt
    16981 atgaaaatca aaaacacttt ccaactgaaa gaactacctc cagtaacaaa ctttgagaaa
    17041 aacggtagta gagctaaaaa gagaagtaaa ataggaagca tccgcattgt taaaatccgt
    17101 ttggcataaa aaaatcttta tttaaactaa aatattatag caaaatttac gccagttttt
    17161 gaacggctga tgtagatatt ttatactttc aaaatgttta aatgtgatta tttatttttg
    17221 aaaaatagct caccagcccg actgaaagtg cttatagaat gataataagt cgcctgccga
    17281 aaacagcgga aaatagcggt gttatgcgga gataatctga cgcgatgcga aagtatattg
    17341 catacttatt ttcaacaatt tagcagagta tttttataag tgtgatataa tagaagtata
    17401 atttgttctg atagtttatt ttatggagaa gtagattttt agaatgcgga gggttcaata
    17461 tggttgagtt tataaagtct aagaaagaaa tgagtgagga ggatattaaa gcaaatttca
    17521 tcactcctgc tattgtatcc aaaggatgga aaaatggtga gcatatcgct tacgaagaat
    17581 acttcactga tggtcgaatt gaagttagag gagataaggc tcgtcgtaaa gaaggaaaaa
    17641 aatcagacta ttcactgtat taccaatttg gaactcgaat tgcaattgtt gaggcaaagg
    17701 ataataaaca cagcgttcga gcaggattac aacaagctat tgaatatgga gagattttag
    17761 atgttccatt tgtttattct tcgaatggtg atggctttat tgaacacgac cgtatcacga
    17821 gagaagaacg tgagctggag ttagacgaat tccctactcg tgaagaatta ttttctcgta
    17881 tgacgaagga aaaaggattg acgtacgaaa ttacagaagc tatctcaact ccatactata
    17941 cagacgcctt ctcaatgaaa acgccacgct attatcagca aatagctatc aaccgtacta
    18001 ttgaaacagt tgccagagga caaaaacgag taatgtttgt gatggcaaca ggaacgggga
    18061 aaacgttcat ggcttttcaa attattcatc gccttcgaaa agctggtttg gctaaacgag
    18121 ttttattctt agcagataga aacatcttag tagaccaaac gatggctgaa gactttaggc
    18181 cattcgaaaa ggtaatgacg aaaattacac caaaactttt gactgctcct gaaaaattaa
    18241 attcttttga aatttatcta gggctttatc agcaactaac tggtgaagat ggaactgaaa
    18301 cacattatca aaaatttgac aaagacttct ttgatttaat cgtaattgat gaagcacacc
    18361 gtggttcagc taaggaaaac agtaactggc gtaaggtaat tgattatttc agttctgcga
    18421 cacagattgg gatgaccgct actcctaaag aaaccaagaa tgcttccaat acggaatact
    18481 ttggtgagcc aatctatact tatagtttaa aacagggaat cgaggatggt tttttggctc
    18541 catatcgtgt tatgagggtt aatttagatg tggatgtgga tggttatcgt ccagaaactg
    18601 gaaaagttga tgctaacgga caattaatag aagataggta ctacggcagg aaagattttg
    18661 ataaaaccat tgtcattgat gatagaacgc aaagagttgc caagtttgtt tctgattata
    18721 tgaagcaaaa caatgcacga tttgataaaa caattgtttt ttgtgttgat attgaccatg
    18781 ccgagcgaat gcgtgctgca cttgtaaaag agaatctaga cttagtccaa gaagactatc
    18841 gttatgtcat gcaagtaact ggtgacaacg ctgaaggaaa agctcaactg gataacttta
    18901 tggatgtcaa ttctaatttt cccgctattg taacaacgtc taaattatta acgacaggag
    18961 ttaatgctaa aacatgtcgt ttgattgttt tagactctaa tatccaatcc atgactgaat
    19021 ttaaacaaat tattggtcgt ggcacacgtc tttatcctca aaaggggaaa gaatttttta
    19081 cgattattga ttttcgaaat gttaccaatt tgtttgctga ccctgatttt gatggtgatc
    19141 cagtgaaggt gctggaaaca ggtgcgaaaa cagtcagtgg ttctacgccc ggtttcgtag
    19201 atgaggaagg tgacccagta gaaaaatata tcgttacaga caagcaggtt accattctta
    19261 attctactgt tcaagtattg gatgaaaacg ggaaactgat taccgaaagc ctgaccgact
    19321 acactcgaaa gaatatctta ggtagctacg ccactttgaa cgattttatc acagtttggc
    19381 atacggcaga taaaaagaag cttatcttag acgaacttta taaaaaagga gtttatctag
    19441 atgctattcg agagtcggag ggaatatcag aacaagaaat cgatgatttt gatttactcc
    19501 taaaacttgc ctatggtcaa aaagaattaa ccaaaacgga acgtatcaat aaactcaaac
    19561 aaagcggata tttatataaa tatagtgagg aagcgcgtgc tgttttggaa attttactga
    19621 acaaatacat ggataaaggt attggagaac tcgaaagcat tgaaacatta aaacttccag
    19681 aatttcagat atatggtgga accttcaaaa tcatcaatac ttattttgga gataaaaaac
    19741 gatatttaca agcaattaaa gaattggagc aagagctatt tacagtagct taatgaaagg
    19801 aaagtatgtc aattacatca tttgtaaaaa gaattcaaga tatcactcga aacgatgctg
    19861 gtgttaatgg tgatgctcaa cgtattgagc aaatgtcttg gttattattc ttaaaaattt
    19921 atgatagccg tgaaatggtt tgggaattag aagaagacga gtatgagtca attatcccag
    19981 aggaattaaa atggcgaaat tgggctcatg ctcaaaatgg ggaacgggta ttgacaggcg
    20041 atgaattact tgattttgtc aataacaagt tattcaaaga gttgaaagag cttgaaataa
    20101 cttcaattat gcctattcga aaaacgattg ttaaatcagc ttttgaagat gcgaacaact
    20161 atatgaaaaa tggcgtcttg ttacgccaag tcatcaatgt tattgatgaa gttgatttca
    20221 atagccctga agatcgtcat tcgtttaatg atatttacga aaaaattctt aaagatattc
    20281 aaaatgctgg gaactcagga gaattttata cgccacgtgc agcgactgat tttattgccg
    20341 aagttcttaa cccaaaactt ggagaatcaa tggcagacct tgcttgcgga acaggaggct
    20401 tcttgacttc gactctgaac cgtttaagta gtcaacgtaa aactagtgaa gataccaaaa
    20461 aatataatac agctgttttt ggtattgaaa agaaagcatt tcctcatctt ttagcagtta
    20521 caaatctgtt tcttcacgaa attgatgacc ctaaaattgt tcatggaaat actttggaga
    20581 aaaatgttcg tgaatatacg gatgatgaaa aatttgacat tattatgatg aatccacctt
    20641 ttggagggtc agaattagaa acaataaaaa ataactttcc agcagaatta cggagttctg
    20701 aaacagctga tttatttatg gctgtcatta tgtatcgttt gaaagaaaat ggtcgtgttg
    20761 gagttatttt acctgatggt tttctatttg gtgaaggtgt aaaaactcgc ttgaaacaaa
    20821 aactggtaga tgagttcaac ttgcatacga ttattaggtt gcctcatagt gtctttgcac
    20881 cgtatacagg aatccatacg aacattcttt tctttgataa aacaaagaaa acagaagaaa
    20941 cttggtttta tcgtttagat atgccagatg gttataaaaa tttctcgaaa actaagccga
    21001 tgaagtcaga acacttcaat cctgttcgtg actggtggga aaatcgtgaa gagattctgg
    21061 aaggtaagtt ctacaaatct aaatcattta cacctagtga attggctgag ttgaattata
    21121 atttagacca gtgtggtttt ccaaaagagg aagaggaaat cttaaatccc tttgagttga
    21181 ttcagaatta tcaagcggaa agagcaactt taaatcataa gattgataat gtattagctg
    21241 atattttgca gttgttggag gacaaataat gacaccagaa caacttaaag caagtattct
    21301 ccaaagagcg atggaaggga aattagtgcc gcaaaatccc aatgacgaac ctgcaagtga
    21361 attattaaag agaattaaag ctgaaaaaga aaaacttatc agtgaaggaa aaatcaaacg
    21421 agataaaaag gaaactgaga tatttcgtgg tgatgatggg aaacattatg ggaagtttgc
    21481 tgatggaagt actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt
    21541 gaggttttct acattggttg aaattgtcag aggtggctct ccacgaccaa tcaaagatta
    21601 tcttacttct gaagtagatg gaataaattg gataaaaata ggtgatactg aaaagggtga
    21661 aaagtatata aataatgtta aagaaaaaat caaaaaatca gggcttaaca aaactagatt
    21721 tgtaaaaaaa ggtacatttt tgttaactaa ttctatgagt tttggtagac cttatatttt
    21781 gaatgttgat ggtgcaatac acgatggatg gttggctatt tcgaactatg aaaactcatt
    21841 aaataaagat tacctattct atattctttc atcaaatgta gtttattctc aatttctatc
    21901 tctaattagt ggagctgttg tgaaaaactt gaatagtgat aaagttgctt ctattcttat
    21961 ccctctcccc ccactatccg aacaacaacg cataatagaa gcaatcgaat cagctttaga
    22021 aaaagtagat gaatatgctg aaagttataa tagactagaa cagctagata aagaatttcc
    22081 agataaacta aaaaaatcta ttcttcaata tgctatgcaa ggaaaattag ttgaacaaga
    22141 cccaaatgat gaatcagtcg aagttttact tgaaaaaata cgagcagaaa aacaaaaact
    22201 ctttgaagaa ggcaagatta aaaagaaaga tttggacatt tctattgttt cccaaggaga
    22261 tgataactct tattatggga acaaagacga aacaacctct tatcctatat atgaaatccc
    22321 agaagcatgg agatatatta aatttgctag cctagttaac ttcagaatag gaaaaactcc
    22381 tccacgcagt gaagctactt tttggggaac tgaaatacct tgggtatcta tatcagatat
    22441 gcctatatct ggttatgtaa ctaatacgag agaatctatt tctaaattag cattaaaatc
    22501 aaagaaaata gacatttcac ctaaaggaac tttattaatg agttttaaat tatctattgg
    22561 aaaagttgcc atattggata ttcctgccac tcataatgaa gccattatat cgatattccc
    22621 ctatgctaat aaagaaaata ttatcagaga ttacttaatg atatttttgc cacttatctc
    22681 tactttaggt gattcaaaag atgctatcaa agggaaaaca ttaaatagta ccagtatctc
    22741 cgaattatta atccctattt ctaatcatga agagatgaaa agaatcattt tcaaagttga
    22801 tttacttttt caaaaagttt ctcaactttt tgagtaataa gttcctgttc ctcaaaagga
    22861 gctaacggaa ttaatagctc gctcagtgta gttttaggaa tattatataa agcttgacct
    22921 gatagtttag ttattgcttt caattgttta taaaataacg gagaggacaa gttaaataat
    22981 agaaattttg aaataatctc tgaactttcg aatggtgtta attggaaaat aaatccacca
    23041 gccacaacac catcatagtc tttatcgatt cttgcaaact ttccaatatg ttctaaagag
    23101 gttgctacag gtgttattag ctgattatgt tttaaataaa cttgctcaga ggagatgaat
    23161 tgtgtatcaa tgtagtaatc attatccaac agagaaaatt ctaaaggctt aatattacca
    23221 ccacgtataa ttctaacacc tttattatta atgcttaaat cgcccttctt gtaagaaaga
    23281 cctgtattca ttgaaaaaat atcttttatt tttataacaa cccaattcat aggtat
//
LOCUS       DAVLCS010000030        23212 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLCS010000030 DAVLCS010000000
VERSION     DAVLCS010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23212
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.030"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            234..887
                     /locus_tag="VXC78_001431"
     CDS             234..887
                     /locus_tag="VXC78_001431"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV0583492.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            897..1361
                     /locus_tag="VXC78_001432"
     CDS             897..1361
                     /locus_tag="VXC78_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0583493.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1374..2642
                     /locus_tag="VXC78_001433"
     CDS             1374..2642
                     /locus_tag="VXC78_001433"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV0583494.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIASEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHYSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2656..2916
                     /locus_tag="VXC78_001434"
     CDS             2656..2916
                     /locus_tag="VXC78_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583495.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2927..4288
                     /gene="pdrM"
                     /locus_tag="VXC78_001435"
     CDS             2927..4288
                     /gene="pdrM"
                     /locus_tag="VXC78_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV0583496.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4442..5410
                     /locus_tag="VXC78_001436"
     CDS             4442..5410
                     /locus_tag="VXC78_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV0583497.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGSVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5426..6418
                     /locus_tag="VXC78_001437"
     CDS             5426..6418
                     /locus_tag="VXC78_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV0583498.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEEISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCSGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            6636..7679
                     /locus_tag="VXC78_001438"
     CDS             6636..7679
                     /locus_tag="VXC78_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV0583499.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7743..9428
                     /gene="lpdA"
                     /locus_tag="VXC78_001439"
     CDS             7743..9428
                     /gene="lpdA"
                     /locus_tag="VXC78_001439"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV0583500.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHSAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9492..10481
                     /locus_tag="VXC78_001440"
     CDS             9492..10481
                     /locus_tag="VXC78_001440"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV0583501.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEAVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10554..11624)
                     /gene="xerS"
                     /locus_tag="VXC78_001441"
     CDS             complement(10554..11624)
                     /gene="xerS"
                     /locus_tag="VXC78_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV0583502.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(12211..13758)
                     /locus_tag="VXC78_001442"
                     /pseudo
     CDS             complement(12211..13758)
                     /locus_tag="VXC78_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            complement(13774..14553)
                     /locus_tag="VXC78_001443"
     CDS             complement(13774..14553)
                     /locus_tag="VXC78_001443"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV0583503.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(14540..15391)
                     /gene="ylqF"
                     /locus_tag="VXC78_001444"
     CDS             complement(14540..15391)
                     /gene="ylqF"
                     /locus_tag="VXC78_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV0583504.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15645..20858)
                     /locus_tag="VXC78_001445"
     CDS             complement(15645..20858)
                     /locus_tag="VXC78_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0583505.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(20902..>23212)
                     /locus_tag="VXC78_001446"
     CDS             complement(20902..>23212)
                     /locus_tag="VXC78_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV0583506.1"
                     /translation="TLNVNYQTDFSNVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPA
                     LNSVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDSLTKLLTADAAIAENNN
                     KVIDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALD
                     NVIELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKE
                     QTKAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVF
                     IIANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNK
                     EKLYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYAT
                     GDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDH
                     PNDPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGK
                     AVAKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDI
                     ITRRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDG
                     MVPYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKER
                     EDKFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNS
                     RVLKLKKAIFKAYLDQTGDFRSSIFENKK"
BASE COUNT         6836 a         4492 c         4478 g         7406 t
ORIGIN      
        1 atggatttta atatatttaa aaatatttca gaaaagataa tcttcgaaag aggtagtaaa
       61 atgcttaatg atttaaaaag taattataaa aaatagccag tctttataaa ctgtattcac
      121 gtattcaaat cgtatatata gtcgatttat taaatcttta gataaactgt aaaaagtggt
      181 ttccatagcc actttttgct ataatagagg cagtaaaaat gaaggagtcg gctatggaac
      241 actcgtcttg gcatgctttg attaaggcgc aattacctga gggttatttc gggaaaatca
      301 atcagtttat ggagcaggtc tattctcagg ggattattta tccacccaag gaaaaggttt
      361 ttcaggctct cttgacaaca ctgcttgaag aagttaaggt ggtaattcta gggcaagacc
      421 cctatcacgg accaggtcaa gcgcagggct tgagtttttc tgtacctgac tctatcccag
      481 ctccaccatc cttgcaaaat atcttgaaag aattgtcaga tgatatcgga gttaagaaat
      541 ctcatgattt gacagcttgg gctgagcaag gagtcttgct tcttaatgct tgtttgactg
      601 ttcctgctgg acaggccaat ggtcatgctg gtcaaatctg ggagcctttt actgatgctg
      661 tgattcaggt ggtcaatcat ctagatagac cagtcgtttt tgtactctgg ggagcttatg
      721 cacgtaagaa gaaggcatta gttaccaatc ctcatcactt gattatcgaa tcagcccatc
      781 caagtccttt gtcggtttat agaggatttt ggggttccaa gcccttttcc aaggccaatg
      841 cattcttaaa agagacagga caagagccaa tcgattggct tagataagga gaaaatatgc
      901 ctcagttagc gacgatttgc tacattgata atgggaaaga actgctcatg ctccatcgta
      961 ataagaaacc caatgatgtc catgaaggga aatggattgg tgtgggtggt aagctagaga
     1021 gaggagagac gccccaggaa tgcgcggcgc gtgaaatcct tgaagaaaca gggctcaaag
     1081 ccaagccagt tctaaaaggt gtcatcactt ttcctgaatt tacaccagat ttagactggt
     1141 acacctatgt ttttaaggtg acggagtttg agggcgactt gattgactgc aatgagggga
     1201 cgctagaatg ggttccctat gatgaggttt tgagcaagcc gacttgggaa ggtgaccaca
     1261 cctttgttga gtggctttta gaggataaac ccttcttttc agccaagttt gtttatgatg
     1321 gggataaatt gttggatacc caagttgatt tctatgaata aaggagaaag cagatgctac
     1381 taatcaaaaa tggtcgtgta atggatccca agtctggttt ggatcaagtt tgtgatgtct
     1441 tagttcaaga tgggaaaatt atcaaaattg cgtctgagat cacggaagaa ggagcagaaa
     1501 cgattgatgc tactggtctt gtggttgctc ctggcttggt cgatattcat gttcatttcc
     1561 gtgaacctgg tcaaacacat aaagaagaca ttcatactgg tgccctagca gccgctgcag
     1621 gtggttttac tactgtcgtc atgatggcta ataccagtcc aaccatttca gacgtggaga
     1681 ctttgcaagc agttctccag tcagctgcca aagagaagat taatgtcaag acagttgcga
     1741 ccattactaa aaactttaat ggtaaaaact tgactgactt taaggcactc ttagaagctg
     1801 gtgcggttgg tttctctgat gacggtattc cgcttgagag cagtaagatt gtcaaggaag
     1861 ccatggagga agccaaaaaa ctcaatacct ttatcagcct tcatgaggaa gatccaggtt
     1921 tgaacggtgt tcttggcttt aatgaaaata ttgctagaga acatttccat atctgcggtg
     1981 ctactggggt ggctgagtac gctatgatgg cgcgtgatgt catgattgcc tatgcaacta
     2041 aagcccatgt tcacatccag catttgtcta aggaagaaag tgttaaagta gtggagtttg
     2101 ctcaggggtt aggtgcagaa gtcacagcag aagtagcgcc acagcattac tctaagacag
     2161 aagcacttct tttaacacaa ggtagcaatg ctaagatgaa tccaccgctt cgtttggaat
     2221 cagaccgtcg tgccgttatc gaaggtctca aatcaggtgt catcacagtt attgcgactg
     2281 accacgcgcc tcatcatgta gatgaaaaaa atgttgagga tattaccaaa gcgccatctg
     2341 gtatgactgg cttagaaaca tccctgtctc tcagcttgac ctatttagta gaagctggtg
     2401 agttgagctt gatggaatta cttgaaaaaa tgacatacaa cccagccaag ctttacaact
     2461 ttgaagcagg ttacttggct gagaatggtc cagcagatat cactattttt gatgccaagg
     2521 ctgaccgctt tgtggactcc cattttgctt ccaaagcagc taattcacca ttcatcggtg
     2581 aaaccttaaa agggcaggtt aaatatacca tctgtaaggg acaaatcgtc tatcaagctt
     2641 gataggagtt agaatatgaa ttattttcga aaacgtaggg agagacaagc gaaatctaat
     2701 agtggaattt actgtcccgc agctaatcgt tccaaaattc aatatgaaac taaagaaaaa
     2761 gctgaccatg cggttcaata tgataacgga ggtttagtta gaagctatta ttgtcgtaca
     2821 tgtgcgtgtt ggcatactac ttcaaaatct aataaacctc cgctaagttt gaaaaactat
     2881 ggtctgaaac tctttggttt agataaatca gaatagaaag agaagtatgt ataagacaaa
     2941 gtgtttacga gagaagttag tattattttt aaaaattttc ttcccaatcc tgatctacca
     3001 atttgccaat tattctgcct cttttgttga tactgcaatg acaggtcaat acaacactat
     3061 ggacttggct ggtgtatcta tggcaaccag tatctggaat cctttcttta catttctaac
     3121 agggattgtg tcagccttgg tgcctatcat tggtcaccat cttggtcgag gcaaaaagga
     3181 agaagttgcg tctgattttt accaatttat ttatttggcc ttgggcctat ctgtggtctt
     3241 gctggggatg gtacttttct tggcaccaat aatcttgaat catattgggt tagaagcagc
     3301 agtagcggca gtagcggttc gctatctttg gtttttatct atcgggatta tccccttgtt
     3361 gctctttagc gtcattcgtt ccttgctgga ttcgctgggc ttgaccaaac tgtccatgta
     3421 cctcatgctt ttgttactcc ctctcaatag cggatttaac tatctcttga tttacggtgc
     3481 ctttggtgtt ccagaactgg gaggggctgg tgctggttta ggaacatcct tggcctactg
     3541 ggtcttgctt gggatttctg ttctggtttt atttaaacag gagaagctca aagccttaca
     3601 ccttgagaaa cgaattccac ttaatatgga taacattaag gaaggagttc gtttaggtct
     3661 gcctattggg ggaactgtct tcgcggaagt ggctatcttt tcagtggttg gcttgattat
     3721 ggctaagttt tcgtccttga ttatagctag tcaccagtca gctatgaact tttcaagtct
     3781 tatgtacgcc tttcctatga gtatctcatc ggctatggct attgtcgttt cctatgaagt
     3841 gggagccaag cgatttgatg atgcgaaaac ctatattggt ctaggaagat ggactgctct
     3901 catttttgcg gccttcaccc taaccttcct ttacattttt aggggaaatg tggccagtct
     3961 ttatggtaac gacccaaaat ttatcgattt gacagcgcgt tttttaactt atagtctttt
     4021 cttccagtta gcagatacct ttgcggcacc gcttcaggga attttgcggg ggtataagga
     4081 tacagttatt cctttttacc ttggtttgct tggttattgg ggcgtagcaa tccctgtggc
     4141 tacgctattt gattccctaa cagattttgg agcttattct tactggatcg gcttgattat
     4201 tagtttgatt gtgagtgggg cgctctaccg ttggcgttta actgtgatta tgaagagatt
     4261 tgaatcttta gcaaaatcca aacgctaaaa agtttgtgaa aaaatattct tgataagaaa
     4321 atcccttgtt ttcacggggt tttctttttt attttgtgaa atttctttta gaaaaacttt
     4381 gacagtattt gccaaaagcg gtaaaatagt aaggtaagaa gaaagttaga aaggcaagaa
     4441 gatgtcaact ttagataaaa atcttttgct agaaatgttc cgtaagatgg aagaaatccg
     4501 tcgcatggac ttaaaaattg cacaattagt aaagaaaggg aaagtgccag gaatgacgca
     4561 cttttctgtt ggtgaagagg cagctaacgt gggggctatg ttagctctca atccagatga
     4621 tctgattacc tcaaaccacc gtggacacgg gcaagctatt gctaaaggga ttgacctcaa
     4681 cggaatgatg gctgaaatcc ttggtaaata cactggaacc tgtaaaggga aaggtggatc
     4741 tatgcatatc gctgaccttg atgctgggaa ccttggtgcc aatggtatcg taggtggtgg
     4801 tatggggatc gctgtcggtg cagccctcag tcagcaaatg caaaataccg gtaaaatcgt
     4861 tgtctgcttc tttggagatg gtgcgaccaa tgaaggtgtt ttccacgaag cagtgaacat
     4921 ggcttctatc tggaacctgc cagtcatttt ctattgcatt aacaacggtt acggtatctc
     4981 tgcggatatc aagaaaatga ccaatataga acatatccat caacgtagcg ccgcttatgg
     5041 aattcctgga atgttcatcg aagatggtaa caatgtcatc gatgtctatg aaggatttca
     5101 gaaagctgtg gaccatgttc gcagtggcaa tggttcagtc ttgattgaaa gtgtaactta
     5161 tcgctggctc ggtcactcat catctgaccc tggtaaatat cgtacgcgtg aagaagtgga
     5221 attgtggaaa caaaaagatc caatcgaaaa cctccgcaat taccttattg aaaataacat
     5281 tgcaagtgcc gaagaattgg aagaaatcca agcgcaagta aaggaagcag tagaagcttc
     5341 tgttaaattt gcagaggaaa gcccattccc accgcttgaa tcagcctttg aagatattta
     5401 cgcagactaa ggagaaagag ataaaatgga aacaaaaaca atgtccttcc gtgacaccat
     5461 tatccttgct atgtctgagg aaatgcgtcg cgatgaaaat gtgttcttga tgggagaaga
     5521 tgtcggtgtc ttcggaggag acttcggtac ttctgttgga atgcttgaag aatttggtcc
     5581 agaacgtgtc cgtgactgtc cgatttctga agctgccatc tctggagcag cagcaggagc
     5641 agccatgaca ggacttcgtc caatcgtcga tatgaccttc atggacttct ctgttattgc
     5701 catggacaat atcgtcaacc aagctgctaa aacacgttac atgtttggtg gtaaaggtca
     5761 ggttccaatg actgttcgtt gtgcagctgg taacggagtt ggctctgccg cccagcactc
     5821 acaatctcta gagtcttggt ttactcacat tccaggactt aaggttgtgg cacctggaac
     5881 acctgcggac atgaaaggcc tgcttaagtc ttctatccgt gataacaacc cagttattat
     5941 acttgagtac aagtcagaat ttaaccaaaa aggggaagtg ccagttgatc cagactacac
     6001 aattccactt ggggttggtg aaatcaaacg ccaaggaacg gatgtaacag ttgttactta
     6061 tggaaaaatg cttcgccgtg tggttcaagc tgctgaagaa ttagcagaag aagaaatttc
     6121 agttgaaatt gttgacccac gtacccttgt tccgcttgat aaggatatca tcataaactc
     6181 agtgaagaag actggtaagg ttattctggt caacgatgcc cacaaaacaa gtggctatat
     6241 cggtgaaatt tcagctatta tttcagaatc agaagcattt gactatctag atgcaccaat
     6301 acgccgttgt tcaggagaag atgtgccgat gccttatgca caaaacctag aaaatgcaat
     6361 gattccaaca gttgaaagta tcaaagatgc aatccgaaaa acttataaca aagactagag
     6421 ttacataata taagttatgt aactaaaata aagctgacga gaaactttgt atcttttagg
     6481 tgcagagctc ttcgtcatta atatcttata ttcgagcacg ggctaaaagc tcggaaaaaa
     6541 gataaatctc cttggcttca tcgaagccat cgtcgatttc ctatttttca gtcgcttttg
     6601 acgccctttg tatcataaat agaattggag aggtcatggc tgatgacaag ctaagagcga
     6661 ctcctgcagc tagaaagtta gcggatgatt tagggataaa cctctacgac gtttctggct
     6721 caggtgcaaa cggtcgtgtc cacaaagaag acgtggaaac ttataaagac acaaacgtgg
     6781 ttcgcatttc gccacttgca aaacgaattg ccctcgaaca taacattgct tggcaggaaa
     6841 tccaaggaac cggtcatcgt ggtaaaatca tgaagaagga tgttttggcc ctgcttcctg
     6901 aaaatatcga aaacgatagc atcaaatctc ctgctcagat tgaaaaagtg gaagaagtcc
     6961 ctgataacgt aacaccatat ggtgaaatcg agcgtattcc aatgacacca atgcgtaagg
     7021 ttattgccca acgcatggtt gaatcttact tgactgcgcc aaccttcacc ctcaactatg
     7081 aagttgatat gactgaaatg ttggctcttc gtaagaaggt tcttgagcca atcatggaag
     7141 caactgggaa gaagactact gtaacagacc ttctttcgct tgcagttgtt aagactctta
     7201 tgaaacaccc atacatcaac gcttcattga cagaagatgg caagactatt atcactcaca
     7261 actatgtcaa tcttgccatg gcagttggga tggataatgg attgatgaca cctgttgttt
     7321 acaatgctga gaagatgagt ctttcagaac tggtggtagc ctttaaggat gttattggcc
     7381 gtaccttgga tggtaaattg gctccaagtg agttacaaaa ttcaacattc acaatcagta
     7441 atttgggaat gtttggtgtt cagtcctttg gtccgattat taaccaaccc aactcagcta
     7501 tccttggtgt cagttcgaca atcgagaagc cagttgtcgt caatggtgaa attgtgattc
     7561 gcccaatcat gagtttagga ttaaccattg accaccgtgt cgtagatggt atggctggtg
     7621 ctaagtttat gaaggacttg aaagagttga ttgaaacgcc aatctcaatg ttaatttaag
     7681 agcaagagta ttcattttta agatatagat aaaggaagga agacatggcc ttagaaataa
     7741 ttatgccaaa agccggcgtg gatatgacag aaggacaaat cgtccaatgg aataaaaaag
     7801 tcggagaatt tgtaaaagaa ggagaaatcc ttttggaaat catgactgat aaagtcagca
     7861 tggaattgga agccgaagaa gatgggtact tgattgccat tctcaaagga gatggtgaaa
     7921 ctgtccctgt aacggaagtt atcggttacc ttggtgaaga aagggaaaac atcccaacag
     7981 ctggagcagc atcgccagaa gctagccctg tacctgtagc aagtacctca aacgatgatg
     8041 gtaagagcga tgatgctttt gatatcgttg tgattggtgg aggtcctgct ggttatgttg
     8101 cagccattaa agctgcccaa ctcggcggta aggttgccct tgttgagaaa tctgaacttg
     8161 gtggaacctg cttaaaccgt ggatgtattc caaccaagac ctaccttcat agcgctgaaa
     8221 ttattgaaaa tatcggtcat gctgcaaatc gtggtatcgt gattgaaaat cctaacttca
     8281 ctgttgatat ggaaaaactt ttagaaacta aatctaaagt tgttaatact cttgttggtg
     8341 gtgttgcagg acttcttcgt agctacggag ttgctgttca taaaggaatt ggtacaatca
     8401 ctaaagacaa gaacgtcttg gtaaatggtt ctgaattgct tgaaaccaag aaaatcattc
     8461 ttgctggtgg ttcaaaagtc agcaagatca acgtccctgg tatggaatct ccacttgtca
     8521 tgactagtga tgacattctt gaaatgaacg aagtgccaga aagccttgtt atcatcggtg
     8581 gtggagttgt cggtatcgaa ctcggtcagg ccttcatgac atttggttca aaagtgactg
     8641 ttatcgaaat gatggaccgt atagttccag ctatggatgt ggaagtttct aagaaccttc
     8701 gcttgatcct tgagcgtaaa ggaatgacca tcttgactgg tactaaactg caagaaatca
     8761 ttgaggaaaa tggtcaactt cgtatcaagg ttgaaggaaa agacgatatc atcgcaagca
     8821 aagctcttct ttcaattggt cgtatgccag accttgaagg tattggagag gttgagtttg
     8881 aattggatcg tggttgtatc aaggtcaacg aatacatgga aacttcagtt ccaggcattt
     8941 atgcaccagg tgacatcaac ggtactaaga tgttggctca cgcagctttc cgcatgggtg
     9001 aagtttccgc tgaaaatgcc cttaaaggaa atcatgcagt tgccaaattg aatttgactc
     9061 ctgcagccat ctacactctt cctgaagtag cagcagtagg tttgacagaa gaacaagccc
     9121 gtgagaaata cgatgttgcc atcggtaagt ttaactttgc tgctaacggt cgtgctattg
     9181 catctgacgc agcccaaggt ttcgtaaaag ttatcgctga taagaaatac ggagaaatcc
     9241 ttggtgtaca cattattggt cctgcagccg cagaattaat aaacgaagca tcaagcatca
     9301 tcgaaatgga aatcactgtt gaggaaatgc tgaagaccat ccacgggcac ccaacttact
     9361 ctgaagtgat gtacgaagcg tttgcagatg ttctaggaat ggccatccat tcacctaaga
     9421 aaaaataaaa cgaagataga ttagactgga aggttatttc cagtttctat catataaagt
     9481 aaagggatat catgaaatac attatcaatc attcaaatga cactgctttt aatattgcct
     9541 tggaagaata cgcctttaaa caccttttgg atgaggatca aatcttccta ctttggatta
     9601 acaagccatc tatcattgtt ggtcgtcacc agaacactat tgaagaaatc aaccgtgatt
     9661 atgttcgcga aaatggtatt gaggtagttc gccgtattag tggtggtgga gctgtttacc
     9721 acgatttaaa taacctcaac tacacgatca tctccaaaga agatgaaaat aaggcatttg
     9781 acttcaagag cttctcaact ccggttatca ataccttggc tcaactcggg gttaaagctg
     9841 agttcacagg tcgtaatgac cttgagattg atggtaagaa gttctgtggc aatgcccaag
     9901 cctatatcaa cggccgtatc atgcaccacg gttgcttgct ctttgacgtt gatttgtcag
     9961 tcctcgcaaa tgcccttaag gtttcaaaag ataaatttga atcaaaaggt gtgaaatccg
    10021 tccgtgcccg tgtaaccaat attatcaatg aattaccaaa aaaaatcaca gtcgaaaaat
    10081 tccgtgattt actcttggaa tacatgaaaa aagagtaccc agagatgact gaatacgtct
    10141 tttcagaaga agaattggcc gaaatcaatc gcatcaagga tactaagttt ggaacttggg
    10201 actggaacta tggtaaatca cctgaattta acgtccgtcg tggaaccaaa ttcactagtg
    10261 gtaaggttga agtctttgct aacgttactg aatcaaaaat ccaagacatc aagatttatg
    10321 gtgacttctt tggtattgaa gacgttgctg cagtagaagc tgtccttcgt ggggtgaaat
    10381 acgaacgcga agatgttctt aaggcgctaa aaaccattga tatcacacgc tacttcgctg
    10441 gtattagccg tgaagaaatc gctgaagcgg tagttggata aatcaaaaag aagttggcca
    10501 actaaccaac ttcttttttt gatatttatt tacataattt aaaatacgta aaatcataaa
    10561 ctatccagag cattcttttg ttcatcacta acaatatggg tatagaggtc agtgacttgt
    10621 gtgctagcat gtcctagttg gtgactgact aaaacttgtg atttagtcgc atcatagagc
    10681 ctagttgcta gtgtatggcg cagtttatgg ggtgttacac gcactttaaa atcctctgag
    10741 tatttagcaa ccattttctc aacgctagaa gcatcgatac gattaggaac acctctgtag
    10801 agagttaaaa aaagggctgt atctgttttt tccgttttat agcgttgatt ccgaatggcc
    10861 agataattct ctaaataagg tttagcaaaa gcagcgacat tgactgagtc acgtttgcca
    10921 ccttttcgag taacatcaat aaccatcatt tttagattga gatctcttag atctagatta
    10981 acagcttcag ataagcgaac accagatgcc aagagaaggg caataatggc taaatctcgt
    11041 tctttatttt tgttgaatga tgagagagct cgatttgaaa gctgttgtgg gtgctcttga
    11101 tcgatataag ttagaaaacc ttctgtttca tcacctagaa agagtttttg cttgatattt
    11161 tcagctctgg cagcaagggt ttctttcttt ttcttggttg aaactttttt cattacatta
    11221 cgatagaaat aaggttcccc ctgatcgttt tcaacctcct cggttagata cttgtaaaga
    11281 ctagaaagtg ctgataaggt tcgattgata gttgtctgtg aaacaccttg ttttgttgta
    11341 ttagcattca gcaagggacg ttcacgtaga taaaggataa aggattccat gtctttctta
    11401 gacatatttt ccaaaactga taaaggaata tcggatattt tatcagcgtt tgaaatacca
    11461 gactccaaaa cccagctgaa aaatcggtca tattccttaa ggtattcgta cagggttgta
    11521 aaactgtagg gcacagccag tttagattgg tagtattcca gaacatacca gggcatgagt
    11581 tgttttagtt tgtcgattcg ttccagtaaa atctcacgtt tcatgtattt tctccataat
    11641 taagtatact agtagtatag catagacttg tatatttttc aagaaaatta tagtttttct
    11701 gaaagatgtt ataggagttt ttcaaagtga taaaaagact tagacctaca aacaaaacag
    11761 aataaggaaa ataataaaaa tctcacccac taaacttctg ttaatactac ataactgaag
    11821 agctatataa ggagctatga gatacaaaac acattgtata atagattgaa actagaatag
    11881 tacatctgga cttctaaaac attgctagaa attgatttga ttgtcctgat tgttttatcc
    11941 tatttctatt tcatttctct atataattgc tattgttttc tttttcatga ttttaatctt
    12001 actgtacaga tttgatacag taaactcctt tctagcttta tactttatca tttctaactt
    12061 aattatagtc ttatttttaa taaagttcaa ttatttatat gtaaaaatcc tcatcagtaa
    12121 aaaataaccg atctcatttc tgagaatcgg ttttctaaat aaatcaaacc gatcatttac
    12181 ataacataaa ttatgtaaat gatcataata caacaacaaa tctttgactt ttccaatttc
    12241 actttttgga ataaccaggt gaatcatatc acccagatac attctggttg agccgttaac
    12301 cgtttggctc ttgccattat ggacttgagt tgtgatgagg acgttgtgtg gtaagttgag
    12361 ttcatgaact tgtttcccag caattttatc agaaactggt atttcgataa gtgtaacttc
    12421 tccttcgcta gatacttctt ctggaagcat tttttccagc atggcttcat agactggcgt
    12481 acctttgagc aaatccatga taatataaga aacaagagtg acaagaccaa gtggcataag
    12541 gttgcgaata tctcctacca tctcagttac gaggatcata gcggttaagg gagcttttga
    12601 tatggctcca aaatagccac tcattcctag aatgacaaat atagggaatt gctcttgact
    12661 gacaagtcca agattgacac agataacacc aactaaggca ccaagcaaag aaccaagagc
    12721 taaaatgggg aggaaaattc ctcctggcag tccacttcca tagctaatca tactccaaat
    12781 aaagcggatt aaaaagtaag ctaataaaac ttggaaacta aaattttgtt cagttaaaga
    12841 aaggacaagc tgatttccgc caccaatgat ttgaggtaag aagattccga ctggtatgat
    12901 aaggataaaa gccaagatgg gataataagc cctatccaaa tggatttttt gaccaatcaa
    12961 gtcataaact cttccaacgt ttaatacagc tttctcatag agaaaacctg aaaatccaag
    13021 gaaaattccc atgacgagat atatccaata ctgatctagg gtcatgggag gaatgttatc
    13081 tggcatatcc aatactggtg tcaaaccgaa catgagtaga gacacaaagt ttgctacgat
    13141 gctggctgct agagttgaga cccagaaaaa gcgcgaaaaa tggtgataga cttcttctac
    13201 aacaaagaga agtgctgcaa taggagcatt aaaggctgcg gctaaacctg ctgcagctcc
    13261 actggcaatc aaggaacgtt cctctactgg actggatttg agccacttgg caattccttt
    13321 accaccaact gctccaagtt gaatactggg tccctctcga cccagcatga gtccactggc
    13381 aatagcaaga atacctagca catatttttt ccaaagaatg ccccaccagt tgagggacat
    13441 gaggcctttc agttcggctt cgacttgagg aattcctgag cctttaatat ctttttctga
    13501 ccgtgttagt ttggcactga gccaacagat gagtatataa aacaaaacca gtacaaaaag
    13561 attgcgcact aagtaccctt gatcttgata aactccttgt atcaggtgga agcccttttc
    13621 aattaagaaa cgaaaggatc cgacgataat tccaacgatg aggccgacaa tgattcctcg
    13681 accaacttgg gatagtatag tgctggatgc aaaggcgaat tctttcttag aacggactat
    13741 ttccgactgt tcctccatgg tatttccttt caattaactt tcttttttac ctaaaaccag
    13801 tgatttaacg ggttcaaagc tggttcggtg aattggggta actcctagtt ttgtgaggcc
    13861 ttccagatgt ttagctgtgc catatcctgc attagtagcg aaatcatagc cagggaactg
    13921 ctgatcgtat tccttcatca attcatcacg tgttaccttg gctactatag atgctgctgc
    13981 gatagagagg gagttggcat ctcctttgat aatggaggtt tgtgaaatgg gcaagtccag
    14041 tttcatggca tcaatcaaaa ggtgctctgg ctgagggctg agctgggaga ttgcttcttg
    14101 catggctagt ttggttgctt catagatgtt gacttggtcg atgacctgat tatctatgat
    14161 accaattcca atcgacaagg cttggtcttg aacggcttgg aaaatctcca gatgtttctt
    14221 tttaggaatt ttcttgctgt cgttgagacc tttaatctta caatttttag gtaaaatgac
    14281 ggccgcagcg actacaggac cagcaagagg accacgacca acctcatcaa tacctacaat
    14341 taaggtcaat ccttgcttat aaagttcttt ttcataagaa agcatggatt ccaagcgcaa
    14401 attttcatct aattcagctt gaatggctct tttacgcttg ctgatttcct tttgaactcc
    14461 tgagcgatta tccttttcaa gctctaaaaa aatagggctt tctaactcct tgactgtcac
    14521 aaggaattct ttgatttctt taatcgttgc catcgaggtc ttccaatgta tctaaggtat
    14581 agttaccgag tttgccatca cggacttcct tcacgaagag actgtaaaaa cggtcatagt
    14641 catcacggaa accgagggcg cgggtcatat ccataataat cacaggcgct tcttcttcaa
    14701 ttttcatttg tttgaagcgt tcagccagct tttctggata atgttctttg aaataattga
    14761 taccaaaaat ggtaacctca tccataggaa gcaactgatc cttgatagct ccagtcaatg
    14821 ccaacttaag tgcaacagtt tcatcctcaa acttaggcca gagaatcccc ggtgtatcca
    14881 agatttccag gtctttattg gttttaagcc attgttgacc ttttgtgacc cctggcttgt
    14941 ttccaacaac agcaatcttt ttaccagcca aacggttcat cagagttgat ttaccagcgt
    15001 ttggaatccc gataatcata gtacgcaagg tttcaatctg aatcccacgt tctttctggc
    15061 gagcaatctt atcagccatg agcttcttgg ccgcatctgt tacaactttt acagtcactt
    15121 gctccttgga gttgatagcc agagtttgga ttccttgtga ttcaaaatac tgacgccatt
    15181 ccttggtcat tgctggatca gccaaatccg ccttatttaa aatcaagagt tttggtttat
    15241 caccaacaat cttggtcaac ataggatttt gactagatag aggtaagcgt gcatccacca
    15301 aaatcgttac aaaatcaaca aattttaaat tttcctgcac ctgtcgacgc gctttagaca
    15361 tgtgaccagg aaaccattga atagtagcca ttgagttttt ttcctttcgt agcaagggtt
    15421 tagagatcct attttatttt actatcgttt gaacataaag ggttctcaaa tgaatgatgt
    15481 tcaaacagtt ttttgtttta tgacatagaa atctacctta tattatatca tgccttcttt
    15541 attttgtccg atgatagcct ttcaagtacc ctatatagaa aaaagccatc aaatgatgac
    15601 ttttcagagg gagcaaaaaa ctgttccttc tatattctaa acatttaaat gtcttcttta
    15661 aacagtttat taaagaaacc gtctgtgttt ttaagaaggg ctttgaagac cttagattta
    15721 agagcaacag tgtgagagaa gtcatctggt ttcttcaaat cttcttcaac tgctttatca
    15781 aataaaggcc ttaactcatc atagttactg atatggacgc catcaatatc gatagcctca
    15841 aaacctttct tagctttagc aagaacttcc ccgtaccaat gtctcttcca ctcttcaaga
    15901 gtattaaagt ttcctttcga tactttatta attattagct tatcgcttag taaaccgtgg
    15961 ttgtttttat ctgcttctgc tttgtattta tttgatacat aactaataaa gccattttca
    16021 taaccataat agccccacat acggaaagca ttgtgcttaa atgataatga accaggagca
    16081 ccttgactcg tattcccacc gtaaattcct gccatcatat tgacatttac gtaagctgag
    16141 tttggtgtaa aatcttctgg tctataacgt ccattacctg gatttccatg ttttgtcatg
    16201 aagttattat ccactaaatc attgacgcta gataaagtca ttaccttttc ttcatctttc
    16261 aaatcacgga tactatccca ttggtttgga cctaaaagat cattatactg aatcttagag
    16321 cgcatttctt tgtcaatctt cttgaaccac ttactattgt ctcctttaat tttaggaagt
    16381 acagcatcag cttctacatg atcaagcaac atcatagctt cattgtagtt tctcatgtag
    16441 cggtcaatgt catcacgtgt ctttaatttg tcaggatctg ggttgtacca ttggttacca
    16501 tcatttggac gatggtaagc catgttaatt ccaagtgcgc cgtattcacc attagtcgtt
    16561 gagctgtcag gtgtttgcaa cataccttga gcataggctt caacgtctgt accttgacga
    16621 tgcttatgac caccgaagta aagcattcta tcgtttacgt gtgttgtttc gtgagtaaag
    16681 gctgaaatac caaatgggct aatcatatcc gtcaccataa acaagacctt gtcatcatta
    16741 tttggattag ggaatattga tgccatagcg cccatacgcc agtctctatc atggtgtcgc
    16801 catgttggac catataattc acgaattgga gctatagggt tacctttact gtcaaatcct
    16861 cgacgaccta caggagaacc attgtaggtc tggttatccc aaactggtgt cggtaccata
    16921 ttttgactct taagaagtct atcacgaaca ttaggcagag ctaatctgga ccagaaatct
    16981 aaataagttt gttgagcatg tgcaacttca tcaatcttag ttttgaactc attacgagct
    17041 tcttctgtat gttttccata tttctcaaat gaactgtacg ccatcgtgtt atatgttgaa
    17101 attaagaaca tatgggcatc tttaagcgtt agaagtggta aaatcatacg accatgaaca
    17161 ccgttatcta aaccatcgaa cacacgatga cgtttatctt tcaactctgt atttgttgtc
    17221 ttaggttctg aaacataaac attcttagct gagtggataa accaatcatt gatgtcttta
    17281 tcctctgtaa acagacgcat gttgtattct aagaagttac gcaaattact tttaccagta
    17341 ttacctgcga tgatttcacg gtaagcatcc tgagtccgat cccctttcaa gttcttttca
    17401 cttgaaccga tgttgatgag tctgtcaata acacttggtg ttttaccata aaaatcaggt
    17461 ttgaacatca tgatgttttt tatacttatg tcaccgtatt tgatatcata gtaacgattg
    17521 agataagtca gagccatcat gattttagct ttattggttt ccactttctt gagaagtgat
    17581 tttatcgcag cttcatcacc attcaattga tggtcttcat tttcgaccaa ggatttgact
    17641 aacttatcta gattttgctt cacttcggca aagctttctt ctaagtatag atctttaata
    17701 taaccattct tacgttcatc cgtattctct gcaggtttat cacgtctact cattaaatct
    17761 cttacttctt gtgaaatcaa ttccacactt gataattgag atttaacatc agcaatcaat
    17821 ttatcacgat ttttaacaac catattcggt gtataaacaa catcaccaag accagataca
    17881 ctatattcac gcacttgttg gactttagaa tcagtattct tagtaacatc catttcttcc
    17941 ttagtaccat cagcatagtg aaccataatc ttatcaatat ctgataaatc ggtcacgaat
    18001 tgaccatcct tcatccccgt aacagaaagg acttctttct tagctaagtt tgaatcttct
    18061 gcaagtttgt taccttggtt gacaatccat tctttattat aaaatggttg aagtttctca
    18121 atattacgat aagctaaatc acgttcggat ttgtagtctt gagttgactt atattcatct
    18181 tctcttctgg ttaaacgatt taagcgattg accacaggtt cgttgatttc gtatttatca
    18241 gcagtaagtc caaaatttgc aattctctta ttagcttcat cttgactaat ttctttaatt
    18301 ttgtcacgag aacgtttgta tgaatgctta cctgaactga cacctttgac aacaaagtta
    18361 cgctctaacc agccatttgt gaaataacca ccatcgtagt ccaaatcgga agaaccaaag
    18421 aactcttcac cattttcaac tctcatcatt gaaatattat cttcaagttt accaaaagga
    18481 agattgctat tgataaatcc acctgtttca aacaaaactt tagtcttaat ggttcctttg
    18541 gtgactgatt tacgaattga accgtattta ccaattccca tagagtcgtt accattatct
    18601 gttttagcaa ctaaaccacc tatacgggct ctgttagcaa caatatcagc ctcgacatat
    18661 gcttttgcaa gattacctct ccaaatctca ccggcaatgc cagccatata ttgaccttta
    18721 tcaccaacac ctgtaagatt accgatgaag gctacatttg tcaactgacc accactatcg
    18781 attttattga cgatacccgc aatattgtta ttagcaacta cattaccagt taccttaaca
    18841 tcttcaacag ttgcattttt caccatattg gcaacaggtg ctattccgtc agcccaaggc
    18901 atattgatat ccacattacc taaattaata tttttcacag aaccattttc aacacggtca
    18961 aataagggac gggcaatgtt atgaattgta tattgtttac catcaacact tgatagatgt
    19021 cccttaaacg tacctggaac atattgtttg ttaggtgttg gtacattcgt tgcattcaaa
    19081 tctgctccga ttttaaatgt accattttta tcagcattca tggcatctac taactcttta
    19141 aagttataat aaacgtcatc aacttttgga actggttttt caatataatg aacatacttg
    19201 ttacgaacct tcgttgggtc tgtatgttga atcaaatctt gagcttcggc agtgatttta
    19261 taaagtttct taccttcttc agtcacttct tcaattttat caactgctaa acgtgttact
    19321 ttattatcac gactagtaat ttttaagtac attttcttca catcttcatc tgaaggtttt
    19381 tcagtcataa aatcactagg tgtttcagta ccatcgtcat ttaccttcac taaattagta
    19441 gatgcgatat ttttaatttc aacttttttc aaatccaagc gaagtggttt ctcttctaat
    19501 gttgcagttt cttctccctt gccacggtca taggtcatag tggtctctat cttatagtcc
    19561 ttgtagaatt ttaaatcttc tacctgctta tctaattgct ctgaagtcaa atctactgtt
    19621 ttgacaattt catttccatc tttaattgtc gcagtaattt tattgattgt gactccatct
    19681 gtattaacta aatgataaga aagagttgcg gatcggttta atacatttgt atttgttcta
    19741 tctaaggtca aaacaggagc cgttttttct ttaggttttt ctttggtacc ttttacaaga
    19801 attttaggct tcatttcttt caaaatagtt actgtttcaa ctgggtcact gatttttttg
    19861 ccatgtaact cttcatagct agtaacaatt tgacgttcgc catcctcacc aacttgtcta
    19921 acagaatcat cgcctataaa tttgctagga tcagattctt ctatagtggt tttaggaata
    19981 gtctctgtcc gaatatcggt atgtaaagaa ggcaactctt ctctttctga tgcaacttct
    20041 gaaactgtag atattggttc agtatactct ggaatgtcgc taacaggtgg ctcaatcaag
    20101 tttccatttt catccactcc tgttgtacct actggctcag tatattctgg gatgtcgtta
    20161 acaggtggtt caatcaagtt tccattttca tctactcctg ttgtccctac tggttcagtg
    20221 tatgctagtt tctcatgaac ttcaggctca acaaggtttg cacctattgg ttgcgtatag
    20281 tcaggcttct catgaacttc cggttcgcct ttctctgtta caactttggg ttgctcaact
    20341 ggcgaaacag ttgatgctgg agaaaccgac gaaacagttt tatcatcaag ctccaagtaa
    20401 ccaacatatc tgtaaccaga aatttgcaac acaccatcac gtccagactc atggatgtta
    20461 gcattcaaat taagtgctga agcagttgat agtgtaacta aacctgtcgc ccctacaatc
    20521 aaaaatgtag ctattttttt atttctatta tcttttgtga taatcacaat aagactcccg
    20581 atagctaaca aacccaatgc agtcataata gattgagaac ttcctgtgtt tggtagtgcg
    20641 tctttttcat aatccaaagc atatgactct ttggattcat caggtctacc ttgtttgagt
    20701 tgatcacgtt cagtttgtgt caaactacta taatctaagt aatgataagt cgatgcacca
    20761 acaactgacg gtgcaaataa aagactcccc aagaataccg aaccaacaat accctttatt
    20821 ttccgaatgg aaaatttatc tttttttaat aatgacaatt ctaatcctcc accttcactt
    20881 tttatttcct aatagtaaac actatttttt attctcaaaa attgaacttc taaaatcacc
    20941 ggtttggtca agataagctt taaagattgc ttttttcagt ttaagaactc tactatttgt
    21001 ctcaggatat aatttggcaa cttcatcctc agcatcaaat tttactgcat cttcaatcat
    21061 tttttcaagt ctattaatat tatcaatagt cactttctgt tgtcgagccc aagaaccgtt
    21121 tggatcgata aaactaactt tatttaactt tccaaattta tcttctcttt ctttatacat
    21181 atctttcttg aaatctatcc aagaattata ctggttatta aatacttttg aaagaacaat
    21241 ttcatcagta actaaaccta tttgtttacc atatgatgta ataacttttc cttgagcttt
    21301 cgcttctttt tcatactgat tagaaatata tggaaccata ccgtctttgt accccttggc
    21361 tgccaataac tcaaatgcaa tacgtcgtcc cattaaatct cctggtgttc ctattttact
    21421 gctcaatgct gaataaattg gtgagaatag attaattgta tagtagccat tccgcttata
    21481 agttgcttca tctacataac ctcttcttgt tataatatca tgttctatca aactgttaaa
    21541 tgtagttaat ttagtaagtt cttctggttt taatctacgt acaacattcg ttgcataaac
    21601 agaatttcca tcaggatcag gtttatattc attttctatt tttcttaata aatcatattt
    21661 ttgatttgta tctaatttag ctacagcttt accttctaat atttcaagca tgtatattac
    21721 atcaaacata ttatgcatat acttatttag atcatcaaca cttccaaatc gttgagttgg
    21781 atctgctact tgaagccttg ttgattcttc tgattgatca tattttaata tggaattaat
    21841 agtgactgtt ggatcattag gatgatcagg agcttgtagc agtcctttag cataaaactc
    21901 tggtccaagt ccatttcgtc ttccatagcc tccaagataa atttctctat ctgagttatg
    21961 tgtcatttcg tgtgtataag ttaccgcacc atctttatca agcatgcgat atgccatata
    22021 atagaatgca tcccctgtag catatgctcc attagaatta tgaacaacat tatttcccgc
    22081 tggaccgaag aaatgtttta tagctggatg attagtttca aaagttgctt gatatgtatc
    22141 tttatcttct ttttcatctg taccaaatct aaatgcatca tagactagaa cacttctata
    22201 taatttttct ttatttttat catctagtat tctataccaa taatcatagt gatctctaaa
    22261 tctaacagcc gcttctttag cttttttctc aacatagtca tttaaatcag ttcctgctgg
    22321 atgttcttta cttctatatc tatcataagc accgaaacct atagtcgaaa tgttggctat
    22381 aataaacacc gatttttcag gtaatgttaa tagcggcaac accatacttg gatatttcca
    22441 agatgggcta gttaatctat catatactcc aattgaatat ggactaccag ctattgattg
    22501 cttatcactt acctctttaa tagtagattt ttcttctaca atatatgctt tagtttgttc
    22561 tttaaaccac tcattatttg ttttatctgg tacaaatgct tttctatatt tctctaatgc
    22621 atcaaataaa ttattagtct tataattttt cgctaataaa acattataag ttataacatt
    22681 attttttgct agtaagttat tatatcccga tttacctagt tcgataacat tatctaacgc
    22741 tgaactattt gatttaccga agaaatccaa gtggtacatg actaaatctt tcgcttttgt
    22801 atcacgatat ttgaagtcgt accaacgctc taagtatgtt aatcctagaa gtaaagcttc
    22861 tttattattt ttaattttct cgattacata attatctatt accttattgt tattttcagc
    22921 tattgcagca tctgcagtaa gaagttttgt caaactatct ttcaaattag tttttgtggt
    22981 attgaattgt tcttctaaat ataactccgt taaactaaca tccttagaaa catctaatac
    23041 ttttctaatt gcctctgatt tatattctac actatttaat gctggtaata cttcatctaa
    23101 aatattttga taattgcgaa gtaatgtatt cggtgtataa attaagtttg taccgcctat
    23161 tctatactct gctacatttg aaaaatcagt ttgataattt acattaagtg tc
//
LOCUS       DAVLCS010000031        22597 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLCS010000031 DAVLCS010000000
VERSION     DAVLCS010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.031"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(164..625)
                     /locus_tag="VXC78_001447"
     CDS             complement(164..625)
                     /locus_tag="VXC78_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0583507.1"
                     /translation="MGKERREQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(592..735)
                     /locus_tag="VXC78_001448"
     CDS             complement(592..735)
                     /locus_tag="VXC78_001448"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV0583508.1"
                     /translation="MAYSTDFKQGALDSIKGGHRHVEAAKVFDVGVRTLFTWEKKDVS
                     KGT"
     gene            1004..1384
                     /locus_tag="VXC78_001449"
     CDS             1004..1384
                     /locus_tag="VXC78_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0583509.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            1483..1704
                     /locus_tag="VXC78_001450"
     CDS             1483..1704
                     /locus_tag="VXC78_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0583510.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            1721..2035
                     /gene="trxA"
                     /locus_tag="VXC78_001451"
     CDS             1721..2035
                     /gene="trxA"
                     /locus_tag="VXC78_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0583511.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            2410..2874
                     /gene="queF"
                     /locus_tag="VXC78_001452"
     CDS             2410..2874
                     /gene="queF"
                     /locus_tag="VXC78_001452"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV0583512.1"
                     /translation="MQHYETVEAVTFAYGQRHHLEIQITREIAKEQGIRHHILDMSLL
                     GQITAQPDFATIHISYIPDKLCVESKSLKLYLFSYRNHGDFHENCINTIGKDLVNLLD
                     PRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLAEQRLFQHDLYPEKIDNR"
     gene            2936..3328
                     /locus_tag="VXC78_001453"
     CDS             2936..3328
                     /locus_tag="VXC78_001453"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583513.1"
                     /translation="MFEVVDKTDEVSSKHCFEVADRTDEVSLKHCFEVADRTDEVSLK
                     HCFEVVDRTDEVSLKHCFEVADRTDEVSLKHCFEVADRTDEVSLKHCFEVADRTDEVS
                     NHTYDKVKLTWFEEIFEEYHTKKPCSSR"
     gene            complement(3353..4021)
                     /locus_tag="VXC78_001454"
     CDS             complement(3353..4021)
                     /locus_tag="VXC78_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV0583514.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGFDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGPIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(4132..4923)
                     /locus_tag="VXC78_001455"
     CDS             complement(4132..4923)
                     /locus_tag="VXC78_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV0583515.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     AIGIQEELFTQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLYADANQ
                     QSVFYQGLQLEIRNVFSNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFSKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(5170..6966)
                     /gene="pepF"
                     /locus_tag="VXC78_001456"
     CDS             complement(5170..6966)
                     /gene="pepF"
                     /locus_tag="VXC78_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0583516.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(6977..7720)
                     /locus_tag="VXC78_001457"
     CDS             complement(6977..7720)
                     /locus_tag="VXC78_001457"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV0583517.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGSKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(7722..8672)
                     /locus_tag="VXC78_001458"
     CDS             complement(7722..8672)
                     /locus_tag="VXC78_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV0583518.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNMD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEMIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            complement(8810..9238)
                     /locus_tag="VXC78_001459"
     CDS             complement(8810..9238)
                     /locus_tag="VXC78_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0583519.1"
                     /translation="MEIEISDFTGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKIYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(9240..10307)
                     /locus_tag="VXC78_001460"
     CDS             complement(9240..10307)
                     /locus_tag="VXC78_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV0583520.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKELAEGV"
     gene            complement(10326..10796)
                     /locus_tag="VXC78_001461"
     CDS             complement(10326..10796)
                     /locus_tag="VXC78_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV0583521.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(11087..11539)
                     /locus_tag="VXC78_001462"
     CDS             complement(11087..11539)
                     /locus_tag="VXC78_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV0583522.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(11576..11749)
                     /locus_tag="VXC78_001463"
     CDS             complement(11576..11749)
                     /locus_tag="VXC78_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV0583523.1"
                     /translation="MTQKEMVKLLTAHGWIKTRGGKGSHIKIEKQGERPITILHGELN
                     KYTERGIGKQAGL"
     gene            complement(11892..12071)
                     /locus_tag="VXC78_001464"
     CDS             complement(11892..12071)
                     /locus_tag="VXC78_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583524.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(12236..12474)
                     /locus_tag="VXC78_001465"
                     /pseudo
     CDS             complement(12236..12474)
                     /locus_tag="VXC78_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12744..14015
                     /locus_tag="VXC78_001466"
     CDS             12744..14015
                     /locus_tag="VXC78_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV0583525.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKASGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            14279..14351
                     /locus_tag="VXC78_001467"
     tRNA            14279..14351
                     /locus_tag="VXC78_001467"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14312..14314,aa:Lys,seq:ctt)
     gene            complement(14561..15880)
                     /locus_tag="VXC78_001468"
     CDS             complement(14561..15880)
                     /locus_tag="VXC78_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0583526.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKNGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVEWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(15890..17506)
                     /locus_tag="VXC78_001469"
     CDS             complement(15890..17506)
                     /locus_tag="VXC78_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0583527.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            complement(17535..18425)
                     /locus_tag="VXC78_001470"
     CDS             complement(17535..18425)
                     /locus_tag="VXC78_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0583528.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            complement(18436..19353)
                     /locus_tag="VXC78_001471"
     CDS             complement(18436..19353)
                     /locus_tag="VXC78_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0583529.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            complement(19504..20505)
                     /locus_tag="VXC78_001472"
     CDS             complement(19504..20505)
                     /locus_tag="VXC78_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0583530.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            complement(20867..22348)
                     /locus_tag="VXC78_001473"
     CDS             complement(20867..22348)
                     /locus_tag="VXC78_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0583531.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
BASE COUNT         6910 a         4851 c         3934 g         6902 t
ORIGIN      
        1 atagcaagaa acttgaggta tttttgctaa aaaaaaaagc attttactat tttatatata
       61 tatatatata tattataaga taagtttttt ataaagacac gcaaatgagt ataaatcagc
      121 taatttttgg tttacattcc tatttttatg cataattatt ctgtcattct ctaatttgtg
      181 aatcaatata tctgattaga aaactaccat tgagtttttg ctccacctca ttagtccgct
      241 caaaacgccg tccgctaatc ttgtcataga ctttctcccc tctaggagcc cctgcataag
      301 gacgatagag gtagcggttg attcccgttt cgtcaatata taggactggt aaatctttta
      361 ggttatccaa aatatcaaga aactcagaaa ctttctcagg cttttgttcc ctaaaactgg
      421 tcgtcttttt taaaatgacc ttaatctgct ttaaaactgc ccatacggag ggcaaagcac
      481 aatcaaaacg ggccgcaatt tcccgtaaaa aagcgtctgg atgagcctct acaaaggctt
      541 tcaattcttc taaagggatc ttacgctttt tgacgactcg ctttttccgc tctaagttcc
      601 cttgctcacg tctttctttt cccacgtgaa gagagttctg acgccgacat caaaaacttt
      661 ggccgcctcg acatgtctgt gccctccttt gatggaatct aatgctcctt gtttaaaatc
      721 agtactatat gccatagctt tattagacca tgcttatttt aaactaagca actatagata
      781 gagaaatgaa ataaaatctg aattcgaatg tgataaggag ttagaaattg aaacaatagg
      841 attcccccat tattcacaca aaaataaaac cactaaaaaa cagagcttgc cagcattctt
      901 gaaaagtagt ataattattg catgcgcaat catcttgtga cgcagagact gcccgttaat
      961 ggactttctt ctattttatg actctaaaaa gaaaggagac actatgacct atttggaaaa
     1021 atggtttgac ttcaatcggc gtcagaaaga aattgaaagt ctcttggaag agaccattgc
     1081 ccaacagagc gagcaaagtc tgaccttgaa agagttctac ctgctctact atctggactt
     1141 ggctgaagaa aaatctctac gccagattga cctgccagat aagcttcatc tgagcccgag
     1201 cgcagtttct aggatggtgg ctcgcttgga agctaaaaat tgcggtctac tcagtcgcat
     1261 gtgttgccat caagatagac gctctagttt tatctgcctg acaaatgatg ggcaaaagac
     1321 actggcctcg ctacaaaaga ctgtcgaaga aagcttggaa gcaggtttgg atttcttgat
     1381 ttaagatgat ttttaaaaaa gttgcgtgcg caatcatttt tcttgacatt ctcttttata
     1441 aggagtaaaa taaagttagc attaaacaaa ggagttttaa atatgattga aattacctat
     1501 atagatgcca gcaagaacga aagaactgtg actttcgagt cttatgaaga ctttgaacgt
     1561 tcgcaacaag cttgccttat cggcgtcgca gactactacc ctgtccaaaa attaacctac
     1621 aagggtcata atttggacta ccatgggact tatggagata tcttcttcta tctcatgaaa
     1681 caagatttaa gccaatataa ctaaaaaaag gagaaataca atggcaaaag caattacaga
     1741 tgcaacattc gaacaagaaa caaaagacgg tttggtctta gtagacttct gggcaacttg
     1801 gtgtggtcca tgtcgtatgc aaggtccaat cttggacaaa ttgtctgaag aactttcaga
     1861 agatgtcttg aaaatcgtta aaatggacgt tgatgaaaat ccaaacacag ctcgtgcttt
     1921 tggaatcatg tctattccaa ctcttctctt caaaaaagac ggccaagttg tcaaacaagt
     1981 tgcaggtgtt cacacagcag aacaaatcaa ggccatcatt gctgaattga gctaatcaaa
     2041 cgagagacca agtactttct ttggtctctt ttttcttgcc ctttgccatt tttcaaaaaa
     2101 tatgctagac tatagtagat tgaaactaga atagtacatc tctacttcta aaacattgtt
     2161 agaaatcgat ttgactgtcc tgatcgattt gtcctgttct tatttcactt tactatataa
     2221 atagaatatt acgatatttg ggatatgcca tcgctaaaaa aaacctcgat ttggtatttt
     2281 ttagctccct aatgggagct ttttacgtgc tctgaacatt tcccattttg gaaggagtac
     2341 tatgaaacgt caatcagcct tggtcgtctt agtggtggtc aagattcaaa aacctgcctt
     2401 ttctggacca tgcaacacta tgaaacagtc gaagctgtca cctttgccta cggccaacgt
     2461 catcacctcg aaattcaaat tactagagaa atcgctaagg aacagggcat tcgtcaccat
     2521 atcctcgata tgtctctgct gggacaaatc actgctcagc cagactttgc gacgattcat
     2581 atttcctaca ttcctgacaa gctctgtgtc gagtcaaaat ccctcaaact atatctattt
     2641 agctaccgaa accacggaga tttccacgaa aactgtatca acaccatcgg gaaagacttg
     2701 gtcaacttgc tagaccctcg ctatttagaa gtctggggaa aattcactcc gcgcggtggc
     2761 atttcaatcg acccctacta taactacggt aagcaaggaa ctaagtatga gggcttggca
     2821 gaacaacgcc tcttccaaca cgacctttat ccagagaaaa ttgacaaccg ctaaagtcat
     2881 actcaatgaa aatcaaagag caaactagga agttagccgc aggttactca aagcagtgtt
     2941 tgaggttgta gataaaactg acgaagtcag ctcaaaacac tgttttgagg ttgcagatag
     3001 aactgacgaa gtcagcttaa aacactgttt tgaggttgca gatagaactg acgaagtcag
     3061 cttaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagcttaa aacactgttt
     3121 tgaggttgca gatagaactg acgaagtcag cttaaaacac tgttttgagg ttgcagatag
     3181 aactgacgaa gtcagcttaa aacactgttt tgaggttgca gatagaactg acgaagtcag
     3241 taaccatacc tacgacaagg tgaagctgac gtggtttgaa gagattttcg aagagtatca
     3301 tacgaaaaag ccctgttcct caagatgagg agcaaggctt tttgagtttc aattattctt
     3361 ctgttccaag gaaatttttt gcaacaaggg ctgcaagaac tccaccagcg attggtgcaa
     3421 ggatgaaaat ccaaacttgt tgaagggctg cgccgcctac caagacagct ggtgccaagc
     3481 tacgagctgg gtttactgaa agtccagtaa tcttcaatcc gacaagaatc atcgccatca
     3541 atgacaaacc gattaccaaa ccagcaatcg ggccattgcc cttgctttct gaagtcacag
     3601 tcatgataac caatacaaac aagaaagttg cgatgacttc aaacaagaaa ccaccaaaga
     3661 cagtgacacc gtttgccaag gcattttcac caagactagc agttgacata cctgagttag
     3721 ccaagaggaa gaagacagcg ccagaagcga tgaaagctcc aacaacctga ccaaggatgt
     3781 agtttacaag ttctgaagat gacaaacgtt tgtttacaaa catagcaatc gaaacagccg
     3841 ggttcaagtg agcacctgaa acagttccga ttgagtaggc tgccaccacg attgccaaac
     3901 caaaggcaaa ggcgattcca aggtgaccaa ggccatcaaa accatttcca aaaacaacag
     3961 ctcctgtccc aacgaacaca agcatgaacg taccgattaa ctcagcaaca aattttttca
     4021 ttttctttct ccttttttca aaaactagat actagtctat caaaagtagg aaagggtttc
     4081 aagaaaattg attggaaatt ttttgaaaat catagaacta ttagctaatc tctagtattg
     4141 aaaagactgg atagcttctt tcaactcatc ttgtaaacta tttctctggt caagttggac
     4201 atagacttcc accagacagg atctaaagtt ggaaaatttg gaaaaatcct ccctttcttc
     4261 tatcggaaaa tcaacagttt ttatccaaga agctacttgt tcttgctcca acttcccttg
     4321 taaaataggt tcatagatca ctcttgctaa acgccaatcc tcatcatctg taaagcgaat
     4381 cgacattctt ttaaatagtt ggccaagtat gtcaaatact tcatgaattc tgtttatagg
     4441 aaagtctgga tgacagacca cctctgtcag taaatcggct ccatgtgcaa aagcatgaac
     4501 ccaaccatac tgacttgaga aacctgttgt atccttttct tttgaaagat agtgcaagcc
     4561 ttgatttgaa aagacattac gaatttctaa ttgtaatccc tgataaaaaa ccgattgctg
     4621 gttggcatct gcatacaaga gatttgcata aacaagtgcc ctaaaagaac gttcaagtgt
     4681 tggcagacct accttatcaa tctctttatc tagtcctaca tcagatgaaa ccccttcagc
     4741 aatgaaatga aattgctcct gtgtaaatag ctcttcctga atccctatag caaagcttgt
     4801 aaaaacaagg tcatcgcgaa tttctggaga aggatctccc aaatgatcaa gcaaccactg
     4861 gatttcctcc tggttataat ttggtttttc ttctgctatt tttcttagta aatcttgata
     4921 catggtcaat acctctacat ttctagcaac tgttcaaaaa ggcagtctta aatgactcaa
     4981 tattgaattc tcaattaaat acaatctgat ataaaatgac gtaaataact atcaatacca
     5041 gttctacagt aagttcaaat ttaacatcac gaccttcaac gacatttttg aaaatagcta
     5101 caactaagac aaatagaatg acgcttaaca agcccataaa catcattcta aaaaattttt
     5161 ctattcccct tactccccca actcagcact gtaggcgata atctggtcaa ctgtgtcaga
     5221 caagaattgg atggtatcac ggagtggttt gtctgttgaa atatcagcac cgataatcat
     5281 ggctgactca agtggtgtct tgctaccacc tgatttgagg agattgagcc agtcttcagc
     5341 tccagtttct gagtttttaa gatgaaggta accagctgtc gagatgacaa gaccagcaga
     5401 gtaagtgtaa ctatacaagc ccatatagta gtgagcttgg cgcatccaag tcaaagctgc
     5461 atcgtcgtcg atttcaatgg catcgcccca aaaatctgtc aaaacttcct tcataatact
     5521 gttgagtttg cttgctccga aggtttctcc ttcttcaatc aatgtataca ccttacgctg
     5581 gaaggcggct tccaagaggt gggtgataaa gttatggaag taggtgtctg tcaagcgatg
     5641 agccagagca aagcgttttt gacgtgggtc attagattgg ttctctaagt aatcactgag
     5701 tagcaattca ttgaaggttg acggtgcttc aacatagtag gtcgacatat gggcattgaa
     5761 gtaactttga tgattgtctg aaaagatgaa ttgaccagaa tgcccgattt catgaatcaa
     5821 ggtatagaca tcgctcaaac ggcctgtcca gctcatgagg acataagggt gtacgcgata
     5881 tgggtccgcc gcataaccac cggaatcctt gccactgtta gcagcaaagt ccacccagcg
     5941 ctcttcttgg taacgagcaa cttcctgaca atattcttgc cccaaaggtt ctaccgactt
     6001 catgaccaaa tcataggcat cgtcaatagt cacttcagga ttcagggcgc tgtccaagtc
     6061 caatttccag tctgcaaagg tcatcttttc aagaccattt accttggcaa catgcttgag
     6121 gtatctctga gcgactggtg caaagtcctt catgatgagg tcaatctggc ggtcaaacat
     6181 gacacggtcc acttcttgtt cagctagaag atagtcaaag acagagtcgt atcccttcat
     6241 atcagccaag agtttttcag acttgacctg agccagatag gctgctgcag ccgtattttg
     6301 gtgcttacga agtccctctg agaaggaacg gaaggatttc tcacgaacct cagcatcctc
     6361 gtgattttgg tagaaattct cataggtgac aaagctgttt ttataggtct tgccatgggc
     6421 ttcaaagtca gccatttcaa aatccccagc tcgcatctta gtataaatgt cctgcggact
     6481 atagaaaact tcaccgagat tggtcaaggc cttctccaca tcagccccta gatagtgggc
     6541 ttttttgatt ttggcctgac gaatagctgc cgtcaagtga ggcaattcac ccaaacggtc
     6601 caagacttcc tcgtctgcta ccaccaaggc atcgtcaaag aaggtcaagg ctacgctggc
     6661 atctgtttca aattccatcc cagcttgggc aatattggca aattcgtcat tgctatagtc
     6721 cgtcgtctga ggcataaaag catagttgcc aatatggctc atctgaatgt agatctgttc
     6781 caattccgca aaggccttct cgaaatcctc aaaagtatga agattaccct tgtagtcacg
     6841 gctaaattgg ttgatgtctt cacgagcttt ctcgattgca cgcaagaaat cctcacggtc
     6901 ttggtatagg gctgttaagt cccagagttc cttctctgga aattctgaac ggtgtttttg
     6961 ttccattttc ttcctcttat ttctctaatt ctactaaaac actaagggct gataaggcgt
     7021 aaagcggtgc tgtttctgct cgcaaaatac gaggacctag gcctgccaaa acggctcctt
     7081 tagcttcaaa actttcgatt tctgcaggtg acagaccacc ttctggacca aagataaaga
     7141 gcagtttgga tcctgtttca agaccagtga ctgcttgcag aagcgcagcg gcttctcctt
     7201 ctttagctga ttcttcatag gctactatga tagagtcaaa ctggtccagc tgagctagaa
     7261 aatctgcttt tttctcgaaa agtttaatac ttggtacaat attacgcttg ctttgctcgg
     7321 ctgctccaag ggcaattttt tctagttttt caactttttt acccaatttc ttgccatccc
     7381 acttggcaac tgaccagtct gcaggaaagg cccagatttg gctagcaccc agttcggtta
     7441 ctttttgagc gatgaactcc agcttgtctc ccttgggaaa tccagatgcg atggtcactt
     7501 ggactggtag ttccacattg tcatttaatt cttggaccaa ctcaaactga cgattttcca
     7561 tatccagcac gcgcgccaag cgcttgatgc catcatcaaa gactaaggta acctcatcct
     7621 cttctttcaa gcgcataacc tgaaacatat gcttactggt ttccttgtcc tcgatagtga
     7681 caggagagat agcactgcct tttacaaaat actgctgcat gctagcctcc aatcacacca
     7741 gagatatcct tggttttctt aaagacacag gtattccatt ccccttgaac catgtgagtt
     7801 tcgaggaaaa atccagctga ttcagccgac tcgcgcacca tgtcccactt atccttgata
     7861 atgccactca tgatcaggta gccttcgtcc ttaaccaaac gataggcatc gtctattaga
     7921 tgaatgagga tatccgccaa gatattagcc acaatcacat ctgcctcaat ttccacaccc
     7981 ttaagcaaat ctccagccgc tacatggata ttttccatgc cagggttgag ctcaatattt
     8041 tcctgagcca cacgaaccgc cacatcatcc aggtcatagg cgaaaatttc tttagccccc
     8101 agaagcgagc tggcaataga gagaacccct gaaccagtcc ccacatctag caccgtttcg
     8161 ccaccacgaa gaacctgttc caaggcaaaa aggctcatct tggtagttgg gtgggttcca
     8221 gtaccaaaag ccatgccagg atccagcttg ataatcattt cccccgcagt cgcctcatag
     8281 tctgtccaag agggaacgat ggtcaaatca tgagtgatac gagctggctc atagtatttc
     8341 ttccagttgt ctgcccagtc ttcctcagcc aaggcagtcg tacctatttt taactctccc
     8401 aaatccataa aatccgtcaa ttctgctaag cgagcctgca agtccgcctc aaccactgtc
     8461 acatccaccg tgtcagggta gtaggctgtc actacgattt cttcttgctg ctccacctct
     8521 gggaaaatct cgccaaagcg gtccatattt cccacatagt ccatgctgtc ttcaatcgca
     8581 acaccttgcg ctcctagctc aatcaagaga ttggaaacca actcctctcc ctcacgcttc
     8641 actgtaactt ttaactcttg ccatgtttcc attattaaga taccaagccc gtaaaacaca
     8701 aaaccaaaat aggaaattct ctgaagacgt ttgtgtctaa gagaagttta tctttttggc
     8761 accgtgttta gggcgggttc agtttagaaa tttaaccgaa ccatcctttc taatcactta
     8821 cttttaaata atcttttaat ctctcttgca actgaggcac aacttgactg gaactaagaa
     8881 attcctcaac attcatcagc tgatagccct gtccttcatc tccaaatacg atactgtcaa
     8941 actggttctg tgtcaactga ccaactagaa aaacggactg tttgtctgca aaaagcatac
     9001 ttgggtaaat cttactccaa agcagacaat cttcagtcag atgaatgccc agttcttcat
     9061 aaacttcacg cgctacacac tcaaaaggac tttcatcacc ttcacgtcca ccacctggca
     9121 gttcccacat attggcccag ggaatgcttg ccttatcatc gcgtaagata gtcaaaagct
     9181 tatccccaca aaacaaagca atcttgcaac ctgtgaaatc agaaatctct atttccatat
     9241 tagactcctt cggctaattc cttttccagc tctgctaaca agttttcata atagcgtttc
     9301 tcgtccctca acattcgact actatccatt ttctgtctag caatcttgag agccttacga
     9361 gttcgatcta catctttctt cacctttaat tgataccagg cttgtatcac ttgaagattg
     9421 gacagtttga gagacagaaa cgatttgacc tgtcgaatac tggcatattg ctccgcttgc
     9481 tcaaaatctc cttccaacaa ggcgatatga agcagggata gttgggcaac tgtctgcatc
     9541 atcggagtag ttgtcctctc aagtaatgct tgaaactgct gtttagctac ttcttccttc
     9601 ccttccaaaa tggaaacttc accttgcata cctaatacac catccgcaaa actccctcgt
     9661 gcatcctcag gaactgcttg aacaaagtct ttcaaatcat attcttgagg agccagcaaa
     9721 gtttgagcag aatgtctcaa taccaggtag gcgtatttgg tattttcagg gtgttgtagt
     9781 aattcccaaa tttttgctcc atcggtgatg tcgactggca aaatgttatt taggaagaaa
     9841 gataaattaa gaaaaatcca agtccctgca aaataccagc ttcttgtcaa aaatccaaac
     9901 actatcgcca ataatatcaa gccgagatga accatcaagc ctcctgaaag catcaggatg
     9961 attctttgat cgctttcatc ctcttttaaa ccaatgtatt gagcaccaac atttttcaga
    10021 atggctgttc tactaagatg aaacctgcct gactttttgg tcaaaataaa atgtcctaat
    10081 ccaaaagcca ccagccgata gcctgtcaag tagccacaaa aagcatgacc cagctcatga
    10141 agaataaaga ttaaatacat gcttagaaga gcgaaggcat aaccaaaagt aaaggctaaa
    10201 actgcggaat accccaactc tgcaaatgcg attgttccac aagcaaaagc tagcataata
    10261 aagacaacag ctagcacata aaccaaataa gtcccaattt tcttcataac acctccaacc
    10321 aactcctagt atcttggata aggataaaat tctccctctt ccaagccaac ttttccttct
    10381 tcaaagactt cttgattcca ttccataaca aattcctctg cttctggatc ttccaaaaag
    10441 tccatgaggg tatctagccc aacctccgca gtatctttga ggaaaagggc aaaataagct
    10501 aaaaactcgc gagaaaatcc ttttttaggt agataaggga taaccgttaa atagtcttct
    10561 gcattgacgg ttgacttggc aggattgtag aaaaggaccg cttcctcaaa aagaatgtca
    10621 tctgatgaaa cctctccgtc ttcatccacc atctccacac ctgcagcatt ttgcgcttcc
    10681 aatagaaaac tcacttctac cgcgtggtta cgcttgtccc aactaatctc aaagtcaaag
    10741 ggaaagttct tgtccaactc ttcctctaaa atatctaaaa atccgtatgt tgccattttg
    10801 tcctctttct atgcgactct ttaatcgccc cgattgctcg gaaatatgct aaaatagata
    10861 ctaccatctt accacaaaat tattttatgt cctaattata ccatattacc tcatttaaac
    10921 ccttggtatc agtgattttc ttaaaagtct gatttcttca tttctcataa aaatcaatat
    10981 aaaaagccct cgaaagggct aataaatcta taaaatcaat aggcgagtaa ctagcacaag
    11041 tggacgtgct tttttattga ctattaccac gataccacgc ttaatcttag gcttgaactt
    11101 tcttatctgc aatagcgtct gtcaaagtct gagaaaagtt aagtcccatt tctcgtccca
    11161 acttatctgc ccattttggt atggtcaaag tctttttaat gggttcctga cttcctaggt
    11221 attctgatac atcaacagat accatagaaa taaaagattt atcaaggtca taggttgaca
    11281 cgaaatcttc atcatcttta aaaggatcat tatcaattaa agacaagcta ttgatatctg
    11341 atggctgagg taactctcca tcactctcta tcaaatctgc aacagttatc cctagccact
    11401 ccgaccccat agccaaagcc tcagaaatcc cctctccttg tgtagctgag tattcaaaat
    11461 ctgggaaatg gacaaaataa gtcgcttctg ttccgtctgt gtcgtcataa taaaataaag
    11521 ctggatacgt aactaacatt tcactacctc catatcaaaa agcagggact gaattttaca
    11581 acccagcttg ctttcctatc cctctttcag tgtacttatt cagctcacca tgaaggattg
    11641 tgataggtct ttccccttgc ttctcgattt taatatggga gcctttaccg cctctagtct
    11701 ttatccaacc atgggccgta aggagtttaa ccatctcttt ttgtgtcata ggtatagcgc
    11761 ttttacctcc tgacaacacc attataacac gtgttacacg tattgtaaag gagtgatact
    11821 tattattcta ttatacataa aagcccctag atgtggttct aagggaaacc aatttattca
    11881 tacctatttt tctaatgagt agtaaaaact gcttctttat cgagcaattc atcatctgta
    11941 tagtcaattg taaaagtatc tcgatctaag acagattgag gcggagttga atgaatcata
    12001 ggaccactgc gtactctata ttttttatct ccaattttta caaactgata ctcttcgaaa
    12061 atcaaattca aaccacgtca acgtcgcctt accgtactca agtacagcct gcggctagtt
    12121 tcctagtttg ctctttgatt ttcattgagt atgattaact ctcaagtctt cgaaatcagg
    12181 attttcaaca gttattacaa ggaggcgatt tactacttca aaaacatcaa ttattctatt
    12241 tttcatattt tttcaaccca ttattagaat gaacttcttg gtaagcaaaa tcaagtttag
    12301 atttaatgtt ttcgtacaaa tctaaaatct cttttggagt atcttccgga agaaaagttt
    12361 tcttttccct gaaataactt gatcactaag aatccaatga cgaatttgtt ttgtaaaaat
    12421 caaaatttcc tgacttggtc catcatttcc attgcttatc acctctcttt tcattatagt
    12481 tcatacaatg acattcagca atattatttc tcaagtcagc acttccactt ctttaggctc
    12541 aactatccta ttttgagctt taaggaaaat caaatctctc atgctgatac ctctcctcat
    12601 taaattaaat agtaaaaaag attctatctc actccctgat tattacaaaa ccattgaaat
    12661 atcacaacta ataggctaga atggacatag taagatatag tagatgagtc attctactca
    12721 aatccacgct agaaaggact gctatgccag acaatctcgc gcttcgcatg cgccctaaaa
    12781 ccatcgacca ggtcatcggt caggagcatc tggtcggacc tggaaaaatc atccgccgca
    12841 tggtggaagc caaccgcctg tcctccatga ttctatatgg ccctccggga atcggcaaaa
    12901 ccagtattgc ctctgccatc gctggaacga ccaagtatgc ctttcgaact ttcaatgcga
    12961 cagttgatag taaaaagaga ctgcaagaaa tctcggaaga agctaaattt tctggtggtc
    13021 tcgtcctatt gctagacgaa attcatcgac tagataagac caagcaagac ttcctcttgc
    13081 ctctcttgga aagtggactg gtcatcatga ttggagcaac gactgaaaat cctttctttt
    13141 ccgtcactcc tgccattcgt agccgtgttc aaatttttga gttggaacct ctgtctaacc
    13201 aagacgtcaa agaggccctg cagatagctc taagtaaccc tgaacgtggt tttgattttc
    13261 caatagaact agatgaggat gcgctggatt tcatcgcaac ctctacaaac ggagatcttc
    13321 gctctgcctt taactcactg gacttggctg ttctctctac ccctgagaat gacgagggca
    13381 ttcgccacat caccttagac atcatggaaa atagtcttca gagaagctac atcactatgg
    13441 acaaggatgg agacggtcac tatgatgttc tatctgccct gcaaaagtct atccgtggct
    13501 cagatgtgga tgccagtctc cactatgctg cccgcttgat tgaggctggg gatctgccta
    13561 gtctcgctcg tcgcttgact gttatcgcct atgaagatat cggtttagcc aatcctgagg
    13621 cccagattca taccgtgact gctctggatg ctgcacaaag gattggtttc ccagaagccc
    13681 gcattctcat cgccaatgtc gtgattgatt tggccctttc tccaaaatcc aactcagcct
    13741 atgtagctat ggataaggca cttgctgacc tcaaagcatc agggcacttg cctattccgc
    13801 gacacctgcg tgatgggcac tacagtggaa gcaaggaact ggggaatgcc caagactatc
    13861 tctatccaca caactatcct ggaaattggg tcaagcaaga ctatctgcca gaaaaaattc
    13921 gtaatcatca ctatttccaa gcagaagata ctggtaaata tgaacgggct ttggctcaaa
    13981 gaaaggaagc tatcgaccat ttgcgaaaaa tctgaaatcc ttttcaaaaa actgcacttt
    14041 cctcttgatt ttttttgaaa aagtggtatc atataaatat agaaacgctg tggtgtacga
    14101 cttcacactt aagtgttgac cgactatttt ttgtattatt agggaaacaa aagtcttcta
    14161 acagcatgta ggccgtctca cacggaaaca gcttcagtta gagcgagttg cccacctgct
    14221 taattgcgcg ggttcaatac aaaccgtgaa gtttcggcac caatacagct ttttatttgc
    14281 cttcttagct cagttggtag agcagtagac tcttaatcta tgggtcgcag gttcgagccc
    14341 tgcagggggc atctaaatca acaggaaaaa gccttataat atagggcttt ttttgcttaa
    14401 ataaaatttt tttcaaattc tttagaaaac tagtttaaat cataatccaa caccaatttt
    14461 acaaatacca taaactaagc ttatataccc aaaacacaaa aagtcctctt tccactattt
    14521 tagaaagaga actttttctt taggagaaat aacttaattt ttaatcaatt cgtgatagct
    14581 cagctggcac cgttaagtaa taagttgcag tcaagcttgc ttcaccttga ttgacaaaaa
    14641 tctcgatgga atttttatct agaacaactt ccaattcttt agcttcaata tctacatacc
    14701 gtcgactagt gtcctgttct tcttcaccta gaattttttg aataagatgg ctacgatcaa
    14761 tgtaaacttg ctgcgcatta ctgtcataac caaattcaag ataatctgta tcatttccta
    14821 agtggtaatg acaatcttta tctatttgga tttgatattg gcctttttta acagggaatt
    14881 gtcttagttt gccatcttcc aatcttagaa ttctaggtaa agtcatggca catgcccact
    14941 tgtgttcttg gtcatgggtt ggaagggtac gcccccatgt ctgcatccaa gcaatcagga
    15001 tacgacgatt ttgatcgtcc aacaatgttt gaggcgcata gaagtcttgg ccatgatcaa
    15061 tttcttgaac tgattctggg ataaaacatt tttctcccca ctctacctta cccgtgaaca
    15121 aaagcgatga gttgatgtta tgatatgagt ctccctcacg ctgataacgc atgggtgaca
    15181 taataaggca atctttccca tctaactcga agtaatctgg gcattcccac ataaaccctt
    15241 ggtgttctac cccttttaaa aagatggatt cgaactgcca ttctactagg ttatcggacc
    15301 ctagtagaac gatacagccc acattatcct tgtgtttggc agctactacg gagtaatagc
    15361 gtccatcttt ttcaaagagt tttggatcac ggaaatcagc agcaatcaac tcatctggca
    15421 agtctgctcc tgttgcaact ggattttgtt caatcttttc aaagtgaatc ccgtcgtctg
    15481 aaaatgccat attttgcact tggcggacac cgtttttttc ttcgatatgc ccagtgtaca
    15541 tgagccagag gcgatcatcc ttgacaatgg cagagcctga gaaacaacca tttcggtcat
    15601 aatcttgatc aggagcaagt gccactggca agtgctccca agtcaccaag tccttacttt
    15661 tagcatgtcc ccagtgcata ggtccccaaa cactatcata tggatagaat tgataaaaga
    15721 gatggtattc tccacgaaaa taaacaaatc catttggatc attgatccaa ccaatctcag
    15781 ctgaaaaatg ttcttcaggc ttatattgag tattaacgag atgtttattt tctgctataa
    15841 aacgattggc tttttctact gtgtatttct tatctcccat aatcaacctc tagtttttgt
    15901 ttgcttggta ttggtcgtag tatttttgtt taatagcgag gtaatcagaa agtccgtatt
    15961 tttcaagttc tttcttgtaa tcatcccact cagtatcaat attgccattt acaatccatt
    16021 cagcacgttt acggtagata tagtcattca tatctgcttc gatatgggca atcttgtcca
    16081 aatcttcctg tgtcataaag actcttggat agttattgtc attgctcatg taaggaacat
    16141 aatattcttt gataagatcc aaacgccatt tggcatcatc aggcatggtt gttactttac
    16201 catagtatga atctaggata gctagtggtc ctcctacttc agtcttttga cgaagttctg
    16261 ctggtgcagt tccgtttagt ggtaagtgtt ttagactatt tgacgcttga tccaattcaa
    16321 agatgttttg ttgtttgtca tctccgtaag ttccccagtt attttgcaca gattggagtg
    16381 gagcgtattg tgcatcaatc catttagctg tcaattctag gtttttgttt acactggtaa
    16441 taaccatctt gtcacgtgca aatcccatac cgtttgtacg agctacgtgt ttttgaccac
    16501 ttggtccagc aagtactggt aaaacatcat aactttcgtt acttccagta acattattct
    16561 tatcccatgt aaagtaaaca ccaaatttct gatcatgacc tttagcaatg taactattcc
    16621 aatcatgttc gaaagcttct ttatcaatca agcctttttc ttgcaattga cggataaatt
    16681 tgacaccttc tttatagtta tcgttatctg ctgtgaaatc aactttgcca tcatttccta
    16741 ctactaaatg atcatcgtta tcccctatac caaatgcagc aaataggaat ttaaaatctt
    16801 cgtttccgtt accactaata aatgaaaatg gaatttcatc agcctctcca tttccatttg
    16861 gatccccgtt tttgaaagct tctaggactt taatcaaatc atcagtagtt tttggcattt
    16921 caagaccaag tttcttaagc caatctttgt taatccaagc catatcgttg acgctgtgaa
    16981 tagactcttt accatctcca agctcttcaa tccatgggaa tgagtaaatg tgcccatcag
    17041 gtgctgtcat caaggccttg tactctggtt tctcatccaa aattttctta agatttggca
    17101 tgtatttatc aatcaaatct tcaactggaa taataacacc ttttttagcc cagttcatca
    17161 agtccacatc tgaagctccg tcgttgtgga tagcatctgg taaatcacca ctagaaatat
    17221 ccaagttacg tttttctgca aagtcggatt ggtagttggt ccagtcaata tgaacgccag
    17281 tttccttctc caaacgttgc aaaattaact tttcatttgg gtctttagga gataacggtg
    17341 aactggctgt cataaacttc aatgttttct tttcttgaag cgggaatgtt acaccttcca
    17401 acttataatc tggacttgaa gctgtatttt ttgagccaca ggctgcaagt actgctaaac
    17461 tagctgtcaa caaaactgct gattttgaga atgttttgaa tttcatgaga aaactccttt
    17521 tattttttct ttttttatcc tttaagtgaa ccagccataa ttcctttatc aaagtatttt
    17581 tggaagaatg gatacataac aatcaatggc aagctggaaa tgacaatagt tgcgtattta
    17641 atcaattcag ctaaacgttt catttcattc atagccgctt gtgctccaat catgtcttga
    17701 cctggttggc tctgaatgag aattttacga agtacaagtt gcaatggttc caagtttgga
    17761 tccttgatat aaatcattgc atcaaagtat gagttccact gtcctacaaa agcataaagg
    17821 aagagaacaa acataattgg ttttgcaaga ggaagcatga ttttgaagaa aatctgtaaa
    17881 tcatttgcac catcaatgac agcagcttca actaattctt caggcaatcc ttggaaatag
    17941 gccctagcaa gaataatatt ccaaacattg acagcacctg gaacaatgat agcccatgga
    18001 gtattgagca ttcccaattc ttttacgagc aagtaagttg ggactaaacc accaccaaag
    18061 aacatagtta caatcaagaa gtagttaatc caacgacgtc caaccaagtc tttcttagaa
    18121 agaggataag ctgtaaacac agatagcaag actgttaaag ctgcaaatcc aaaagagtat
    18181 agtagagaat tgataaaacc tcttagaata gattggtcac tgaatacacg ctggtaacct
    18241 tctacagtcc aatcggctgg attaaagcta atccctctac taaccagaac cttaggatcc
    18301 ataaaggatg ctacgacgat ataaagtaaa ggaagcaaag tcatcaaaac gataaagaca
    18361 ataatgattt tatttaagag taagatacgt ctatcaaatt ttgtatccat aatcgaattt
    18421 ttcatacttt cctccttaaa ttccttcacc attattcatg cgtttaacga tttggttaac
    18481 tgcaacaagc aatactacgt taatcactgc attaaacaaa ccaaccgctg ttgagtaaga
    18541 atagtctcct gatacaagac caactttata gacatatgtc gagataattt cagaagttgg
    18601 caaatttaac gatgtctgca tcaagaatgc tttttcatat ccgacattca taattccacc
    18661 tgcagctaaa acaaattgga taaccataat aggcttaaga gctggaatat caatgtgcca
    18721 gattcgttgg aagatattgg ctccatccag tcgagctgct tctactaagg ctggatctac
    18781 atttaccaat gttgccgtgt agagcgttga agcccagccc attccttgcc agataccact
    18841 aaagatgtat aagggtctaa agaagtctgg atttgtcaag aagtcagcct tcattccaaa
    18901 catagaaaga aaattgttga ttggtcctcc cactgaaaag aagaggaaaa tcataccgac
    18961 aataacaacg actgagataa agtttggtgc gtataaaatg agctgaattc gttttttgac
    19021 tttttcactc aagagttgat tgagcataat cgcaagaatg attggtggta aaaagccaag
    19081 caataaacca tagatactta attttaatgt gttggctaac aagataccaa agttgggaga
    19141 ggatatgaat tttgtaaact cagaaaaacc aatccaatca ctccctaaaa ttccttttaa
    19201 aggattgtaa tctttaaatg cgattaaaac cccatacata gggatgtatt taaagataaa
    19261 ggttaaaact aaaccgggga cagtcatcaa taacaagagt ttttgtttct tgattctttc
    19321 ccaaagagaa acttgcttcg ctttgctatt catagcaacc tccttttttt gaaacgtttc
    19381 attttttcta taaaagatag cgcttggcgc tgtcttttta tttctttttt tgaaacgttt
    19441 catttttgtt ttaaaaataa atctttttat ctgaattcat tctatcattg atagcgcttt
    19501 ctgtcaagac ttattttcat tttttgttgt ttttccttca acaaatttta ctggtaggat
    19561 tgtctgcaaa ttaacagtct ttccatcaat tatatcaaac aaaatacgaa ccgcttcttt
    19621 tgccatttct tccaatggtt gttcaatagt tgaaagtaga taatctctat ctccagccat
    19681 tttaattcca tcgtatccaa taatttggac atcatgagga atacgtttgc catttttttc
    19741 tagtatttca atcacatcca aagctgtaaa atcgttgatt gtaaaaattc catctataga
    19801 agaattttct tccaagaaac tctctagctt tccataatag tcagtaactg tctcatccaa
    19861 atcaaaaata ctaagaggta ttttatgctc ttggacatac ttttcaaatg aaattctacg
    19921 acgtttggtt tcattaatgg ttgtattatg tccgcccaca aaggctaaat gctgacatcc
    19981 tttactaatt aattgtttag ctgcttctct tccacctgca tcattatctg atgaaacaca
    20041 aggaatggca atatctgagt atgtgcggtc aatactaaca aagggaattc ctgacgtcaa
    20101 gtaatgttca attggactat aggtaatggc aaccactcca tcaactttat tatgacgcaa
    20161 catctccaga tagtcttgct ctctatttgt accatttata gaacataaga gtaatttgtt
    20221 atttctctta tagacttcat tttccacatg catagcaaat tctgaaaaga agggatgcca
    20281 gatacttggt acaatgattg caatcgtttc tgttcgattt tttttcattc ctctagcata
    20341 gtaatctgga atgtaattca aagttttaat cgcttgttcc acttttttca aagttacttc
    20401 tttaatgcct ttttctttat taattacacg tgaaacagtt ccaacactaa ctcctgcttc
    20461 taaagcaaca tctttcatgg taattgattt tctttgttct accatattat cacctccttt
    20521 caatatatag tatcatgcaa atgcttttta agcaactatt tctcaatcat ttttggccag
    20581 atcatttatc ccatcatgaa taaaatcact ccaattagct tttgaaaata cttcaatttt
    20641 catgtgtaaa catctacata aaacaggaaa agccttggtt ttatggcttt tttcgtatct
    20701 tctacaaaaa aagcaagagt tttagagggc tataaatcta gatgtacatt ttgcttaaat
    20761 gattgaaggt cttttcttaa caaaaacacc ccaaaaatta gattttttct gtctaacttt
    20821 tgaggtacag ttcaaacgcg aaatagcgtt tttttgttat ttttggttac tcatctaatc
    20881 gaataaacat catggcattt aacaagtata tgagtgagac cgtgtttata ttatttgaat
    20941 agatgagtct cttattttca ataggaggaa taataaaatt agaaataatg atatcataag
    21001 gtgaatcttc taaagattcc tttgataatt ctaattcagt ccaaacttcc agttcaaaat
    21061 tattgctaca gtaataagaa agtgtctctg caacgaattt tgcatgatac tgatcaaaat
    21121 tactcataac taaaaccttt agtttaggct gattttgtag caaattaatc accaaatgtt
    21181 tggtatgagt gatgaaggta taagatagat gatttaccat cattgaacta gaacaaacct
    21241 caagagtctc taaatagtga gaaagctctt tttttatatc tgaaacaaat tttggaaaaa
    21301 tattttgaaa gttcctgatt gtattccctt tttgatcaaa taaaataaac tcagtaaaca
    21361 actcttgacg atacagatgt gcggtattat gcagatgcca aatcagatta tccttattct
    21421 ccatttcaat ctgatacttg actgaaatct gatcaataaa atcactcaat agatggtaag
    21481 atttttcaac ataactatcc ttttttacgc atttcataaa gagactttca tctatgaaaa
    21541 acattttttg aaagtaagac acaaataatt ggcaaacaac ttcttcatct aaagagatat
    21601 tgtattctga ttcaaaactc tgagcaacac cttctattcc ttctgcctgc attaaaaaat
    21661 ccaaactttg gtcgttaaaa gaatctttat ctacttccat aaaatgacca aactttattc
    21721 tatataggtt cgtaactagg agcaacttta gcattctatg cgttgacaaa ttcattggaa
    21781 agcttgtttc cttataaacc aattctaaca attgagatag tggctctgat gaaaaatttt
    21841 caaatggcca ttctaggaaa taatattttt ctgaaaaata ttgtgcaaaa aagtaacgaa
    21901 tgtctctctc atttccaatg atttgaacag gggtcagact gacttcaaat tgaaattgcc
    21961 ttttaatcac tttattgatt tggctaataa tacgatagag cgaagatgaa ctgatataaa
    22021 attctttaca aatactctca gcttgacaac cttcattaaa gaagatgaat tctaaaatcg
    22081 aaaaatgagt tgaatgttta aagaaatgat ggtaaaccat ttcaatatca ctatcatcgg
    22141 tattaataat gcgtatacca ttagtagaag aatgaaaaat caagtcagga aaagcagatt
    22201 taacatggga tagatcatct ttgactgcac gttctgtaca atttaataac tctgctagtt
    22261 cagaacgatg aaaccaacgt ttatgttcaa ataataattc taataattct aattgcctat
    22321 gacttttttt agataataaa tctctcatga atatctttct ctctttataa attatcggat
    22381 taaacctctt gcaattatac cacaaagaat aggtatagca tgatataacg acttttccta
    22441 aaatctttta tttcgtataa taacactacg gagacaatat ataaacaatt ttcttatttt
    22501 accgtctatt gagggcgtga atacagaatc aaattcaagt ctaaagatta tatttttaat
    22561 tttaaaaatt atataatagc aacaattaaa gaatttg
//
LOCUS       DAVLCS010000032        22582 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLCS010000032 DAVLCS010000000
VERSION     DAVLCS010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22582
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.032"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            <1..191
                     /locus_tag="VXC78_001474"
     CDS             <1..191
                     /locus_tag="VXC78_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0583532.1"
                     /translation="KPLTVEDKTYNHALSKERSKVENIFAKVETFKMFSTTYRNHRKR
                     FGLRMNLIAGIINHELGF"
     gene            complement(180..827)
                     /locus_tag="VXC78_001475"
                     /pseudo
     CDS             complement(180..827)
                     /locus_tag="VXC78_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(936..1454)
                     /locus_tag="VXC78_001476"
     CDS             complement(936..1454)
                     /locus_tag="VXC78_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV0583533.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1681..2550)
                     /gene="rsmI"
                     /locus_tag="VXC78_001477"
     CDS             complement(1681..2550)
                     /gene="rsmI"
                     /locus_tag="VXC78_001477"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV0583534.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETSLKGECLLIVEGASQDVEEKGEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2553..2870)
                     /gene="yabA"
                     /locus_tag="VXC78_001478"
     CDS             complement(2553..2870)
                     /gene="yabA"
                     /locus_tag="VXC78_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV0583535.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2910..3800)
                     /locus_tag="VXC78_001479"
     CDS             complement(2910..3800)
                     /locus_tag="VXC78_001479"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV0583536.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLQT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3797..4435)
                     /locus_tag="VXC78_001480"
     CDS             complement(3797..4435)
                     /locus_tag="VXC78_001480"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV0583537.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILKEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4655..5452)
                     /gene="proC"
                     /locus_tag="VXC78_001481"
     CDS             complement(4655..5452)
                     /gene="proC"
                     /locus_tag="VXC78_001481"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV0583538.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLSVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5456..6718)
                     /locus_tag="VXC78_001482"
     CDS             complement(5456..6718)
                     /locus_tag="VXC78_001482"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV0583539.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(6728..7858)
                     /locus_tag="VXC78_001483"
     CDS             complement(6728..7858)
                     /locus_tag="VXC78_001483"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV0583540.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7938..9821)
                     /gene="cbpE"
                     /locus_tag="VXC78_001484"
                     /gene_synonym="pce"
     CDS             complement(7938..9821)
                     /gene="cbpE"
                     /locus_tag="VXC78_001484"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV0583541.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(9824..10711)
                     /locus_tag="VXC78_001485"
     CDS             complement(9824..10711)
                     /locus_tag="VXC78_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0583542.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10701..11162)
                     /locus_tag="VXC78_001486"
     CDS             complement(10701..11162)
                     /locus_tag="VXC78_001486"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV0583543.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(11159..12067)
                     /locus_tag="VXC78_001487"
     CDS             complement(11159..12067)
                     /locus_tag="VXC78_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0583544.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            12060..12257
                     /locus_tag="VXC78_001488"
     CDS             12060..12257
                     /locus_tag="VXC78_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0583545.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12309..12980)
                     /locus_tag="VXC78_001489"
     CDS             complement(12309..12980)
                     /locus_tag="VXC78_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0583546.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(13034..13255)
                     /locus_tag="VXC78_001490"
     CDS             complement(13034..13255)
                     /locus_tag="VXC78_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV0583547.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCSRGTYDLGYIGGGNHLCKGSAARF"
     gene            13527..14336
                     /locus_tag="VXC78_001491"
     CDS             13527..14336
                     /locus_tag="VXC78_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0583548.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14517..15392)
                     /gene="aguB"
                     /locus_tag="VXC78_001492"
     CDS             complement(14517..15392)
                     /gene="aguB"
                     /locus_tag="VXC78_001492"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV0583549.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGGVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15402..16487)
                     /gene="aguA"
                     /locus_tag="VXC78_001493"
     CDS             complement(15402..16487)
                     /gene="aguA"
                     /locus_tag="VXC78_001493"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV0583550.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16484..17611)
                     /gene="nspC"
                     /locus_tag="VXC78_001494"
     CDS             complement(16484..17611)
                     /gene="nspC"
                     /locus_tag="VXC78_001494"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV0583551.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17611..18870)
                     /locus_tag="VXC78_001495"
     CDS             complement(17611..18870)
                     /locus_tag="VXC78_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV0583552.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(18867..19727)
                     /gene="speE"
                     /locus_tag="VXC78_001496"
     CDS             complement(18867..19727)
                     /gene="speE"
                     /locus_tag="VXC78_001496"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV0583553.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            19983..20698
                     /locus_tag="VXC78_001497"
                     /pseudo
     CDS             19983..20698
                     /locus_tag="VXC78_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(20664..22139)
                     /locus_tag="VXC78_001498"
     CDS             complement(20664..22139)
                     /locus_tag="VXC78_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV0583554.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT         6587 a         5174 c         4020 g         6801 t
ORIGIN      
        1 tcaagccgct aacagttgaa gataaaacct ataaccatgc gctatctaag gagagaagca
       61 aggttgagaa catctttgcc aaagtagaaa cgtttaaaat gttttcaaca acctatcgaa
      121 atcatcgtaa acgattcgga ttacgaatga atttgattgc tggtattatc aatcatgaac
      181 taggattcta gttttgcagg aagtctaatg taattctcaa gctgtgagtt cattatgatt
      241 tgtaaatcct atatatcttc agcagctaaa aacacatttt gaaatgttcc aagtccgttt
      301 tcaccaaaac tatattctct cttactatac ttactcttat tattctctat atagttagag
      361 tcaaggttct taacctcttg aagttcattt tctttacttc tgaggttaaa atcttttact
      421 tctgaagtta agttttttga cttctgtaag tcattttctt ttacctgaaa tatactcata
      481 aagtctttaa cataaatgat gttcggctta ccaagtccaa gccttactct ttcgatcagt
      541 cctattcctt tttttatatc aagctcatct aatgttttta tggcagttgg ctttgagata
      601 tttcttcttt tcataatttc ttcgacagta aaatagataa atactctgcc ttccttgtct
      661 atccagttat tcttaaatga cattcctgtc tatttaagaa gtatggaata aaggataatt
      721 gcttctgctg ataagccccg aaattcttct ctatcaacta atatctccgg tacttttaag
      781 aagttaaatc ttttcgcttc tctgttataa aaatattcaa agtccatgca agatcacctc
      841 ccttcttaaa aatttgcaaa gaaaaagacg atagtttttc ttctatcgcc tttggtaacc
      901 atttttatga aattttttaa agttaaaaat ataatttata atactatctt cttccatttt
      961 ctgattttag ttctgaaagt tccaaaaggt gcaaccgtat ttacatgaat aaacttatac
     1021 acttcccaag tcgctgtttt agtcgcttca tcagcccact ttctcatatg cggttcaaat
     1081 aattcttcct cactcaacga atcaatcatt gcagagatag aatgaatatt ttcatttaat
     1141 tttgctttca actcttgcag agataaatga gcgtaggtat ctgtgaacca ctgatataat
     1201 tcaccaagtt gattccattt aaatttatcc gatggtgttt ttacttgaag cccctttctt
     1261 tcatcttctt cccatttaag aaccaagttg gtccaaccaa cctgataagc aaggttttct
     1321 gctggagttc tgtcaacttc atcagctctc ttatctttta aattttctgg aatattatca
     1381 aattctaaaa tatatttctc aaatgttttc tctatctcag cttttagttc ttctttattt
     1441 tcgtatgttc gcaaaaaatc accttctttc tgatttatca atcctttgat ttaaaatgac
     1501 cttatttttc tatttatacc ttctaagaac gctataactg ctgctccaac catcggtatt
     1561 ccgtatgggc ttaataaaaa acttaatacc aaagcttcta taccaagtga tacatcttta
     1621 tattatcatc actaattaag ttaaacagaa acagacagaa ttattacatc ctgtctccct
     1681 ttattgtttt tcttcccagt cgtggtaggc agcgtagagt tgactcttat tccactggta
     1741 aatcttagct acttccttaa tagcttgatt tttcttcata ccttgctgaa tacgagcttg
     1801 gatttctaag aacaagtctt cctcgccttt ttcttccaca tcctgactgg caccttcaac
     1861 aatcagaaga cattcaccct tgagagacgt ttcagcaatg ctttccagca attcagaaat
     1921 tgtacctctt tggtattctt catagatttt ggtcaattcc ctgaccaaga caacggagcg
     1981 gtcaccgtag acttctagca tattttccaa tgtatctgcc acacgatggg gcgattcata
     2041 aaaaatctga gtttcaggat agtctttttt cgagtcgaaa aattgctttt gctggcctga
     2101 ttttctcggt aaaaagccgt aaaagatatg tggctgcggc gctaaaccac tggcaatcaa
     2161 ggcggaaatt cctgcagagg cacctggaac tgtaacaact gcaatttctt cctcaatagc
     2221 tgccttaacc aaatcatgac cagggtctga aatgctaggc aaaccggcat cagagacctg
     2281 agcaatactt tgccctgctt tcaagaaacc aatcaaatca ggaatttttt ccttggcatt
     2341 gtgctcatga aaactgatct gcttggtgga aatgtcaaaa tgcttgagca aaagccctgt
     2401 attgcgcgta tcctcagcag caatccagtc cacttctttc aaggtctgga tagcacgaaa
     2461 agtcatatca tctagattgc caatcggcgt tgccactaga tacagcttgc catagggaga
     2521 ctgcccctta aaactttttt gaatttgcat gcttactccc tgtataacaa ctcatcacag
     2581 aacatacatt cttcgtcctg ctctcgacgt tgtccataaa aatcattaca tacgtgaaat
     2641 ccatcacggt aaatacgacg gacactttcg cgaacatgct tggccttgac gggagcgtct
     2701 gcttccacct cacccaagcg ttctcgcaac ttactatttt ccaagcgaag agctgtattt
     2761 tcttctacca agctcttgag atttttcttg atggcttcca catcggctaa ggttaccaat
     2821 aattgttggg aaaaatcatc cagcgcgtca aataattctt ttttgtccat aaaacagccc
     2881 tttcctttct ttatcattca tttttgagtt tatatttctt tcaagaccag atattccatg
     2941 gcattttgaa agctgacatt agcttgccac atttttctag cttctagtaa atcttgtaga
     3001 atcactctta ctcttacctg caagaggtcc tgcccacaga gaacttcaag aatccgtaaa
     3061 acctgatcct gtttttcctt atcatctgcc aagttggcta atttggcaac ctgtagataa
     3121 ctttcttttt tcttagctac taaccaagtc tgcaggcgtt cactttcatc gaccaaggtc
     3181 caaaaacttg cctgattagc caacttttct gcttcagctc gcgattgact aaacttagct
     3241 aaaagagtcg cttttttctt aacaagtccc atttgttcta agagtaagat aagtttttct
     3301 tcttgctttt taaagtggaa gatctgagtc cgacttcgga ttgtcggtaa catcttttcc
     3361 tcatcgctag tcaagaagaa aatataaact tcactctggg gttcttcgat gaccttgagc
     3421 agagaattgg ctgcgttggg atgcatttta tccgcttgct cgataataaa gacctgttgc
     3481 tggctttcaa tccctgcttg agaaaactgt cccaccaatt cccgaatgcg ttctgtcttg
     3541 atgacctgat tgactggctt aatcaaggtg acatctggaa actcttcctg ttcaatcagc
     3601 ttgcaacttc ggcatttctc acatggtaag acgccaactt tatccgtaca aaagaggctc
     3661 ttagctaaaa attgcgccat ttccaagctt ccaaagaaac ctgaaaagag ataggcgtga
     3721 ttgagctggt cttgttctaa gatacggaca aaacggtcaa actgagctgg ttgccaagcc
     3781 tttagttgat cttgtttcat ttggccaagc ccattccgtc aaacaagaca gccttggtag
     3841 tttccacaac ttgctccaaa gggagactag catcaatctt gacaatgcga tttccctctt
     3901 tatccagaag agaaaggtag ccttgacgaa cttttttatg caagtccaac ccttccaaat
     3961 ccaaacgatt aacctcgcgg tcactattcg cagcaatacg agccagccct tcttccacct
     4021 cgatgtcaaa atagagtgtc aaatcgggtt tgaggccatc tgtcgcaaac tgattgagcc
     4081 agtcaatggc ttcaatatct aagccacgac caaatccctg ataggcaaca gaactatcga
     4141 taaaacgatc catgatgacc aacttgccag cttcaagggc tggaagaact ttttccacca
     4201 aatgctgtct gcgactggca atatagagaa gtagctctgt tttagcatcc atctgagtat
     4261 gacttggatc caaaatcact tcccgaatct tctccccaat caagactccg ccaggttcac
     4321 gggtcgtcaa cacctctact cctttttcct ttaaaattgg tagcagagcc tctaaaacac
     4381 tggtcttgcc tgctccctct ggtccctcaa gagagactaa aaatcctttt gacatgtcta
     4441 actcatttct tttttactac ttctattcta tcaaaaaaat aggggtttgt gacaatcttt
     4501 ttgtcttctc atttcatact caatgaaaat caaagagcaa actaggaagc tagccgcagg
     4561 ctgtacttga gtacggcaag gtgaagctga cgcagtttga atttgatttt cgaagagtat
     4621 caaccaccat aaaagaggca gataaaacta cctcttattt acctagttct tgtgttcgtt
     4681 tataggcttg atgaactgcc tccatgactg tgcctcgaaa agcatgcgct tctaggcttg
     4741 ctacgccagc aatagtcgaa ccgcctggac tacaaacttg atctttcaaa actccaggat
     4801 gttgctggct ttctaggacc aattgcccag ctcctaccac agtttgggct gccattttca
     4861 aggctgtttc tcgtggtaat cccgtctgaa cacctgcatc tgccaaggcc tcaataaaga
     4921 gatagacaaa ggctggtcca caacctgcaa gacctgtcgc tgcattgatt aagctttctc
     4981 ctaattcaac cgagagacca gccttggcta aaagctgaca aaagatctca ctgtcctcag
     5041 ccctgcaatt aggagacaag gcataactaa tcactccttg cccgatagaa gcaggggtat
     5101 taggcatcat acgaataatt cggtgttggc ttgggataag acttgctagt ttttctaagg
     5161 tcaatccagc tgccatcgaa atcaaaagaa gactttctct tttttcaagg atggtctgat
     5221 attgagaaag cagttcagaa aactgagcag gcttaactcc tagaaaaatc acatctgctt
     5281 ctgcaaacat ttcttcattg ctggaagcct gaccaccaaa gtctgcaatg aaagcatcta
     5341 ccttagcttg actacgattg gcaaggagaa tctcatctga cgtcctagtc tgcaagacag
     5401 attttgccaa gctagcaccc atattcccca aaccgataaa tccaatcttc atctcttact
     5461 cccttatctg cccatcacca gcaaccacat acttgtagct ggtcaactct ttcaagccca
     5521 ttggaccacg cgcgtgcaat ttctgagtag aaatccccat ttcacaacca agaccaaatt
     5581 gtcctccatc tgtgaaacga gttgaggcat taacatacac cgctgcagag tccacttgat
     5641 ctgtaaagta tgctgcagct tcagcatttt ccgtcacaat agcatccgaa tgatgggtac
     5701 tgtgggattc aatatgcgca accgcttctt ctaaactgct cacaacctta acagctagaa
     5761 tatagtctaa aaactcggta tcaaagtctt gtgcttgagc agcttgacct gaaacaaact
     5821 ggcttgcttt gctatctagg cggaattgaa ttggttccaa cccagcttct tttcgatctg
     5881 caaccaacat ttgatccaag cgaggaagga tgcttgctgc cttgttttca tgaaccagca
     5941 gaacctccat ggcattacaa acagaaggac gactggtttt agcattgttg atgatagaca
     6001 gcgccttgtc ttcgtctgca tccttatcca catagacatg gacaatccca gtccctgtct
     6061 cgataacagg tacaatcgca ttctcaacca ctgcattgat caagccagct cctccacgag
     6121 gaatgagaag gtctagatag cccttggcct tcatcatagc ataactactt tcacggctag
     6181 tatcctccac cagttgaatc acatttggat gaatagtagt cgtctccaag cccttcttca
     6241 aggctgtgac aatggcatgg gttgtttgat aggcatcctt accactacga agaacaaccg
     6301 catttccact cttaagagtc aaagcagccg catcagacgt cacatttgga cggctttcat
     6361 agataatacc gatgacaccc atagctacac gtttttttgt gataaccaaa ccattttcaa
     6421 gctgacttgt ttctaaaact tcaccgattg gatctggtaa ggcaaccact tcacgaattc
     6481 ctcttgccat cgcttctata cgatctgcat ccaaataaag acgatccaac atcacatctg
     6541 agattttccc cttagccgct gccatatcga gggcattagc cgctaaaatt tcctcagtag
     6601 cagccactaa gtgatcagcc atggctagca aggcttggtt tttcacttct tcactagctg
     6661 tgttaatcga ttttttaaca gcctgtacct gttcaaattg ttcttgtcta ctcaccatag
     6721 tttacctcta aaattctgta aaaagtagtt ggatttcagg agtaatggaa atccagtcgt
     6781 cacggtaaat caagacaccc ttggcttttt gagaacgcaa catatcctcc aaagcagatg
     6841 ctccaaattg cacgcgtcct tttccaagtg attttccact ttccttatca aatactgtca
     6901 cgatatcacc gtaagaaaag actccttctg cttcaacgat accagataag agaagactct
     6961 ttccatgttg agagagagct tccgcagccc ctttatcaac ccaaatagaa ccttgactct
     7021 gagcatagaa ggcaagccat tgtttctggg tacgaagccc cttctcttga gcaacaaagt
     7081 aagaaccatc ctcggtctcc tctgccgcct caatcatgga atctgatttc aaggatgagc
     7141 agatataaac aggaactcct gattccgtcg cgatagttgc agccttgatt ttggttaaca
     7201 tacccccagt tccgtttgac gaaccagctc caccagccat atcaataatc tcacgattga
     7261 tggtctcgat tctctccaag cgtttggctc ttggatctga attaggattt ccagtataga
     7321 gaccgtccac atctgtcaag aaaactaaaa ggtctgcttg gaccatcgcc gctacttgag
     7381 cacttagagt gtcattgtcc ccaaccttga gctcatcaat aacgacacta tcattctcat
     7441 tgatgatagg aattgcccca cggttgagca aaaccgacaa agcctgatgg gcatttttat
     7501 aacgacgctt atccacaaag tcatcttggg tcagcaagat ttgtgcagaa acgatttgac
     7561 gcaagagaag attggtcgta tattcttcca acaaaagtcc ctgccctacc gctgctgaag
     7621 cctgtttatc agcaatttta gtcggacgct ttttaaatcc taaggctcca aaaccagccg
     7681 caatggcacc tgaagacacc aaaatcaact catgaccagc ctcgtgcagc atagccaact
     7741 gctgggtaat atcctttacc ttactacgtg ataaacttcc atcctcattt gtcagagaag
     7801 aagtacccac cttaaagaca atccgtttgt atttcatagt ctcactccga ttattcatat
     7861 ttatccatta taacatgaat aacaggaaat agaaaagagt tgataggaaa aagaaggccc
     7921 taaaaccttc ttttctacta ctgttctgat tccgatttgt ttacactcgt ttcagagctt
     7981 tgtgaagttg aggatgtcaa atcttgacta gttgaagaat ttgtaacact ttcatgttga
     8041 ctcgtttctt tattttcaag atcctttttc actacttctt tggattcttt tatttctgaa
     8101 tgacttgtag ttttaattgt agcagatttc tcgatcggaa catccactaa ccaggcacca
     8161 cttgaatcca cagtatagcc ttctggtgtc ttaccattca caagtaattg accattttct
     8221 ttcaagaagt accatttatc cttgtcttta atccaaccta tagctcgtga accatctgtc
     8281 ttgtagaaat accaatcatt tgccttttta agccagcctt gcttcatagc tcctgattct
     8341 tctagatagt aatgatgtcc agcaacttct atctcacctg tcttcatgat accagtagaa
     8401 tccatatagt accaggcttc tttatctttt acccagcccg ttttcatttc ccctgatgga
     8461 gcaaagtaat accattgccc cttatattga agccaacctg tcttcataga gccatcaaca
     8521 tccaaataat accactgctc tttatcttga atccaaccaa tttccatctg gttttctttg
     8581 ttaaaataat accagattcc agcgattttc ttccaatttt tagcagcaac accagagtct
     8641 gtcaaataga accaacgatt gttccatttt ttccattgat tctgtaataa gatacccgtt
     8701 tggttaaagt aataccattc acccttaatt tcattccaac cgacagcata ttctcctgta
     8761 gaatcaggcg cttgatacca ccagtttcca tatgaactct tatgccaacc agcttgaaaa
     8821 cttggaatcg gcttgtagga agttgaaatg tttactaaac cgtcttgtcg aatatcaaaa
     8881 actgttgcat catagtcttt gctggctgca ttgattctct caattcctcg ttctttgagc
     8941 caattaacat actcactatc aacaccattt ttccaaggta gactatccga agtttgaaca
     9001 atcaaactcg gactcaaatt tttaatgaaa tccttggtat ttgatttgtt ggtatcatgg
     9061 tgatgattaa acttcatcaa atcaactttt ccaatgagag gaccatactt gtcttctgct
     9121 ccatgaacat tatctaaatc gcccccaagg taaattttct tgccattgac tttcaccacg
     9181 ctaatcaagg aattggaatt gtcatcccaa attttcttta attcacccga tgaatcagtt
     9241 tcattttcat aattatagag ctgaatatcc atgtccccaa actgaaaatg agcatcccct
     9301 tgtgtgatat tttgaataac tgaaacacct ttttctgcag cagtctgtaa aaccttatca
     9361 tagccataca gattatccca tagacgttca gaattagtaa tacgactatc actatatttc
     9421 ttaagataga ctcggtcaac tggataggta gacagtaatt catcaacatt tccaatatga
     9481 tcactgtggg tatgggtcac caaaataaaa tcaagttttt ggacacccaa ttccttcaaa
     9541 cgacgaaaga cacggtctgt tagaacatgc ttataagacg tttcaattcc ttctctccat
     9601 ggatagcgag aatcacttcc atctgggaaa tcataatctt ctcctgtatc caccatggca
     9661 aaatgtccat tgctttcaag aataatcgca tcactgccac cttcttgaac attgataaag
     9721 tggattttat ttcctgaact ttcttgagcc tgaacattcc cataccatga caaacctaaa
     9781 aaagcgccta caagtgctaa actagttaat ttctttttca ttcttacttt ctcaatctct
     9841 ccaaggtttc cttaaaaatc tctgggatat ctgctttaaa ttccaaggtc ttacctgttc
     9901 tcggatgagt aaaacctaaa gtcttggcat gaagaaattg tccatgtcct ttcaaagtct
     9961 tgcgaggacc atagacctca tcaccagcga ctgaatggcc gatataagcc atgtggacac
    10021 ggatttgatg agtgcgccct gtctccagtt gcaactctac taagctataa tcgccaaagc
    10081 gttccaagac gtgaaaacgc gtcactgcag gcttcccttt agcagttaca gcctgtttct
    10141 tacggtcttt ttcactccgg ccaatcggcg cttcaattac accacgatca ttaggcagat
    10201 ttccatgaac aatcgcccaa tatttgcgga gagacttttt atctttgagt tcttgggcaa
    10261 gtactagatg cgcatcatcg tttttagcaa tcatgagaag acctgacgta tccttatcaa
    10321 tacggtgaac aatccctgga cgcagaaccc cattgatacc cgacaagtcc ttaatatgat
    10381 acatgagggc atttactagg gttccactgg tatgaccagc actcgggtgc acaaccattc
    10441 cctgaggttt gttaacgaca gccacatcct catcttggta gactatttct agcggaagat
    10501 cctcagccac atactctaat acctctggtt ctggcacatg gtaagtgacg acatcaccct
    10561 cttggactgt gtatttagct ttcttgactt gaccattgac caagacctgg cctgatttaa
    10621 tttgttcatt cgcgagacta cgtgataatt ctgacaaatc tgacaaagcc ttatccaaac
    10681 gcagaccacc agtttcaatt ttaatttcca tttatttcct cttttagcat tgcaatcaat
    10741 aaaataatca ctccaaccgt cagatagcta tctgccacat tgaaaattgc aaagttgata
    10801 aagtcaaggt ggaacatatc cacaacaaag ccctgactga ccctgtcaat aaagtttcca
    10861 agaccacccg cgattattag agtcaaaccc aagaccatcc agaatgagtc ctccatgtgt
    10921 ttatgtaaat accaaatggc acctatcacg acaaccagag taatgacagc gaataacaac
    10981 tgctgatctt gtaagataga aaaggctgca cctcgatttt gcaggtaggt caagctaacg
    11041 aaattgggga tccaggagcg cacttcaccc agtggaatct gctggacgat ataagatttg
    11101 accaactgat ccagcccaat taaaagcagt acaatgactg ccactattgc tctttttttc
    11161 atgatttcct cttttgatca aaatattctt gcatgacttc tacgaagaga gtcccagctt
    11221 gactaagctc cacttcttca cgtttaacat agaccatgcg gttatctagg ttatccttga
    11281 gacgaataac tgtaatgcca ttaacactgt cactatctaa aaatccagaa cctgtcgcat
    11341 aggcgtccgt ccgctccaaa ataccattca aggtggcacg gtctgtcaca ttaaacatct
    11401 gtgagctagc gctggtatcg acaaagttct ctgaataata aaggtactcg tctttctctt
    11461 gagtgaaacg aaccgttggt aaatccgcta aatcctccat gactaattcc tctttctggg
    11521 ctaaaggatg accctcacag agataaatat gggtatggaa aggaatcaat tcgatgacct
    11581 ccagacctaa cttttcaacc cgttgcataa tccccttttt attttgattg ttgaggtaga
    11641 taatcccaat ctcactatgc ccttgcgcca cttcatctaa tatttgaaca gtagttgatt
    11701 caaaaatacg gaagttctta tagtcaggat agcgctctga aaaggccgta atagttggtg
    11761 gtaagaagtc atagtgctgg ctagcaacgg aaaattcatc tttttcttct tcaggattgg
    11821 catactgatt ttgaaaaata tcaaatcctt taaccaattc ttgcgctttt tcataaaatt
    11881 ccatcccacg acgggtcaag aaagtccctg agctggtccg acggaaaatc ttaaagccca
    11941 actctttttc caaatcacga acagaaatag acagactcgg ctgactaaca tacatctttt
    12001 cagcagcttc acgaaaagta ccactattgg caatagccac aacatagcgt aattgttgaa
    12061 tgttcatctt ctacccccaa cttctttatc ttttcattat accatatttt agaagttttc
    12121 caaaaaggaa aaaagaacat cctattcttc ttaactatct tcactatctg cctttctcac
    12181 gccaatctta ttttcaaaat caattcaaaa aaataagtgg ctacacacca cttcagtatc
    12241 ggaaagaaaa acgttgacta tttgtgaaaa aagaaaatgc cggaaaattc cgacattttt
    12301 ttagtaagct aacttcctga aaataggagt aaccaaacat cccagaaggc agtgatattg
    12361 atgagaatat gaactagtat tggatagtag agatttttag tcatgcgata caatagagct
    12421 aaaatcagac ctccactagc ataaatgaaa aaagcaagag gagttaaagc aaaattgata
    12481 tgaatataac cgaaaataat agcagaaagc aaaacatctc cgtaccaagg tgagtttttg
    12541 aaaaaggttg tcataagcac acctcgataa atcaattcct cagcaatagg ggcgatgaag
    12601 caaacgatga gcaagaaata agggaactcc tgtctcccca tcatttctat cgtttcattc
    12661 aaagaaatct gatttgaaga cagggatatg aaatacgaaa agaggaagtc agacatatat
    12721 gaaatgatgt agcccagtaa aaggtagatg aagtacctca gctgccactt gaaatgaaaa
    12781 attttctttc ctgcaaaaac cagtagatag atgaccgcta agaaaagaac tccgctctcc
    12841 atcaaaagca gaatctgaaa aaattcacga cttgctggta gatagggctt tgcgaggtga
    12901 ttgaaaactc tccaaaacca agttgatttg taaaaaatta aggacaatgc tagtaaaatt
    12961 tgaatagccc gttttttcat attaaattct ctgctttctc cacttgtttc ttcatattac
    13021 taataaattt tacttaaaat ctcgcagcac ttcctttgca aagatgattg cctcctccaa
    13081 tatatcctaa atcataggtg cctctggaac aaaatccatg aaccggcaga gttaatactg
    13141 gttctatttc ccaatcgtac ctaccattag gatttttacc atatgaatct gctccacctt
    13201 gtatcagctc taattcttca tttgttagat ttatattttt tgtcattaaa atcatgatat
    13261 atttcctcca ttattcttca gattagttga gtaatctgat actcatacct acttacaaaa
    13321 aaactattat attaagttgg ttttttaatt tgtctagttg caacattgac aaacatagta
    13381 tagcatatct ttgccaaata tcctcttcaa atcatgaatt gtcatcaaaa catcttaaac
    13441 tataaaatca attagtctca agctttctat caatttcttc tccaaaatat gctataataa
    13501 tagcaaaaga taaagaagga agacctatga ttaaactact agccttggat atggacggca
    13561 ccctcctcaa tgaagccaag gaaatcccac aagctcacat tactgctatt cacaaagcca
    13621 ttgaaaaagg tgtcaaactg gttctctgta cgggtcgccc ccttttcggt gtcctcccct
    13681 actacaaaaa actggagctt gacctccaga acgaatatat tattgttaac aacggttgtt
    13741 caactcacca gaccagtgat tggagtctag ttgactggaa agaactgagt ccagctgaca
    13801 tcgaatacct ctatgacctt gctgaaaaga gtgatgttca gttgacactt tttgacgagt
    13861 cacattattt tgttctcggt ggcaaaccca atcaagttat tgaaaatgat gctaaactag
    13921 tattttcaga cctgactgaa atttctcttg aagaagcgac tagtggaaag ttccggatgt
    13981 tccaaggtat gtttttagga acaaaagaac aaacagacga ttttgagcag cgttttgctg
    14041 aagagctttg ccaacgattc agtggagttc gttcgcagcc tgtcatttat gaagcaatgc
    14101 cgcttggaac gacaaaggct actgctcttt cacgactagc tgagattttg aagattgatt
    14161 cctcagagat tatggccatg ggcgatgcta ataacgatat cgaaatgctc cagtttgcag
    14221 ggcttgggat tgcaatggga aatgccagcg attatgtcaa atctcttgcg gatgccgtta
    14281 cctcaagcaa cgaagaagac ggcgttgcgc gtgctattga gaaatatatt ctataaaaaa
    14341 gaaaagcaaa tagacagaag ttactgctat ttgctttttt gctaatattt taaaatacgg
    14401 actaatcaat agacaagaat agcgaatcat aaaaatcgat ttactagatg ccatagtatc
    14461 ttatagttgc taataagaag ttagtctagc agaatgaatc tctcatttct cccacactaa
    14521 tctgtaattt gtctatacat ttctggtctt ctatctcgaa acaagcccca gtttagacgt
    14581 tcacttgctc ccttgtctag gtcataagta gctaacagaa cagcttcttc ttgtctttca
    14641 gctcgttcta gaatagctcc tgtttcatcc gtcataaagg aggaaccgta gaagtcaaga
    14701 ctggaactct gtccgccatt ttcctcacta ggagtaacct cctctaaacc ataacgattg
    14761 gctgcgatga ctggaacaat attcgctgct gcgtgccctt gcatagtacg ttgccagtga
    14821 ccacaactat ctgtatccaa aattggctct gaaccgatag ctgtaggata aaagagcaat
    14881 tcagcaccat tcaatgcaag acagcgggct gtttcaggga accattgatc ccaacagata
    14941 ccgataccaa tcttagcata gcgagtattc cagaccttga aaccagtgtt accaggcgtg
    15001 aaatagaatt tttcttgata ataatggtca tctggtatat gggtctttcg ataaacgccc
    15061 agcactcccc catctgcatc aatgacggca atagagttat acaagacatt accatctttt
    15121 tcatagaaac tgattggtaa aacaacttgt agttccttag caatcacctt aaaatgctga
    15181 atggcagtat tttccgctac agattgggca tactggtagt agtcatactg acgttcctga
    15241 cagaaatagg gatgttcaaa caactcgggc aagagaataa tttgggctcc ttgctcagca
    15301 gcctgacgta ctaaacgctc tgcggtttgg atatttgttg ccacatcctt agcgcattgc
    15361 atctgaatgg ttgcaactct tacatttctc atctttttct cctattctgg aatttgttgg
    15421 gtgatacagt ggatattgcc accacctaag agaatatctc tggctggtat tccgacaact
    15481 ttacggtctg ggaaacactt gctgaggata tctaaggcca cttggtcgtt tacatcctca
    15541 aactgtggaa ccaagacagc cttgttggcg atataaaagt ttacgtagga agctgctagt
    15601 cgttcacctg cgtatcgctc ttcttctcct tcttcataga tgtagcctgg caaatcttct
    15661 tctgtcacaa cttgtcgaac tgcagggata ggcaatttat gaatggtgaa gtgacaacct
    15721 tttgcatctg tttcctgttc taagagttcg agatctgctt ttgacatggc atactgggga
    15781 tcattttcgt catctgtcca agccaaaaca acctcagcag gaccaacaaa ggcaacaaca
    15841 ttatcgacgt gttcattggt ttcatcctga taaataccat aaggaagcca aataactttt
    15901 tcagcaccaa gactttctaa taatgtgttt tcaatctcct ctttagtcag gttaggattg
    15961 cgaccaggac taagcaagca actttcagtt acgagaatag ttccttgacc atcgctatgg
    16021 attgcgcctc cttccagtac aaaaggttta gcatcataga caggcctttc caaggcctca
    16081 gcaaaacgac tggctacttg gtcatcctct tcataatctt gataaagacc atcataggtg
    16141 cctccccaag cattaaaggc ccaatccacg gctaatttct tacctttatc attgacgaga
    16201 atggttgggc cagtatcacg cgcccaggca tcattggtgg gaatgtctaa ataaacaacc
    16261 ttgtctccaa gataggattg ggcttcagat agataggcct gctccaccaa aagatagact
    16321 ctttcccctt ctgctatggt ctcgatgatc tgagtaaatg ctcttttagc agcctttcct
    16381 tgaaaaggcc atgatcctgg tcgagtcggc catatcatga gggtaccatg atggggttcg
    16441 tactctgctg gcatgtgata gcctaatttt tttggactgt ccatcatgat aatctccctt
    16501 taaagtcttg atagccaaaa gctttgagta agctacagtc tccctgttcg tccatgagat
    16561 agagacttgg caatccaata ccattaaagg tattattttt gacaaaagaa taaatggcca
    16621 tgtcttgaaa ataaagtctg tctccgattt ggactggatt ttcaaaacta taatcaccaa
    16681 tcacatcgcc agtcagacag gtattagaag aaagtctgta ggtatgggct ttttcctgtg
    16741 actcaaagcc atttctcaaa ggtggacgat agggcatctc aagtacatca ggcatatggc
    16801 aggtcgcaga ggcgtctaaa accaagattt ccataccgtt ttctacaata tctaatacct
    16861 cagttgctaa ataacccgca ttaagcgcaa tggcttcacc aggctcgata tagatttcaa
    16921 gattgtaagt ttttcggata cgcttgattt ctgaaatcag caaatccaca tcgtaacctt
    16981 ctcttgtaat atgatgacca ccacccatat tgagccattt tacctcatgt aagtagggac
    17041 caaactgttc ttctactgct ttcaaagttg tttgtaaatc atctgctccc tgctcgcaaa
    17101 gggtatgaaa atgaagtccg tcaaccaaat ctagcaaatc actcggaatc ttgtctatag
    17161 taactccaaa gcgagaacca ggtgcacaag ggtcatagag cgcgtgatct ccttgagttg
    17221 aacactgagg gttgaggcgc aaaccaacac tgacaccagc ctctcgacaa cgagccccat
    17281 gcttacgcaa ctgtctctct gagttaaaga cgatatggtc tgttatccca agcaattcct
    17341 ccatgtcctc atccttgaaa gctggtgcaa aaacatggac ttcaccagga aattcttccc
    17401 ttgccaattt ggcctcatag agtccactag ctgtcgtacc tgatagatac tggctaatca
    17461 agggataagt tttgtagagg gaatatgcct tctgggcaag caagaccttg caaccggcct
    17521 cttcttgtac atattgtaga atgcggcaat tagcttctaa cttggccaag tcaataacat
    17581 aggctggtgt tggtacttgt tctaacttca ttagtccacc atttgtggat tttcaaccac
    17641 aacccatggc aaaccatact cattcaaagc ttccatgaat ggatctggat ctaactcctc
    17701 aaggttatac actccagctt gtttccaagt tccgttcatg actaattttg tcccaatcat
    17761 ggctggaacg cctgtcgtgt atgaaattgc ttgtgacccg acttctgcat agcactcttg
    17821 atggtcgcaa acattgtaga tgtagatagt cttttcaacg ccatctttga cacctgtaaa
    17881 gatacatcca atattggttt tacctacagt acgtgggcca aggctagcag gatctggaag
    17941 caaggctttc aaaaattgaa ttggaacaat ttcttggccg ttaaagttaa tggtatccgt
    18001 acgaaggagt ccaacatttt caagacattt catgtgcgtc aagtaagatt gaccaaaagt
    18061 cataaagaaa cgaatgcgtt tgacacctgg aatgttcttg gccaatgatt cgatttcttc
    18121 atggtgaagg agatacatat ctttttgtcc aacttgaggg aaatcatact cacgcttgat
    18181 agacatagct tcgacttcga cccatttccc atcttcccag taagaacctg gcgcagaaac
    18241 ctcacggaga ttaatttctg gattaaagtt ggttgcaaat ggataaccgt ggtcaccgcc
    18301 attacagtct aaaatgtcga tataatggat ttcatcaaaa tagtgtttga gggcataagc
    18361 tgaaaagaca ctagttacac ctgggtcaaa accagaacca agaagagcag tcaagcctgc
    18421 ttctttgaat ttctcttgat aagcccactg ccatgagtag tcaaagtagg ctgtaaaacc
    18481 aagttcctta caacgttttt cgtagatagc acgccactca gggtcttctg tgtcttctgc
    18541 ttcgtagttg gctgtatcga tatagtgaac acctgttgcc aaacaagcat ccataatggt
    18601 taaatcttga taaggcagag ctacattcaa aacagcttct ggtttgtagc tttcaatcag
    18661 ggcaatcact tcttcaacct tgtcagcatc aagtgctgca gtttcaattt tagtacttgt
    18721 tttgccttct agcttcgctt tcaagtcatc gcattttgac ttggtacggc tagcaatcat
    18781 aatctctgta aatgtttcgc tatcttgaca aatctttgaa atagcaactt gggcaacgcc
    18841 cccacaacca ataactagta aacgactcat ttttttcctt cctcttcttc taaaatgtcc
    18901 tcaacatact tgggcaacat aaaggctccc acgtgtaagt ttgcagtgta gtattctgtg
    18961 aaaagctggc gttttttcca gccttccttg tcaaaatctt tgacagggtg gtattttttc
    19021 gatgcaaatc caaacaacca atagccagct gggctagttg gaatatgggc ctgataaacc
    19081 cgactgattg gaaaggcttg attgaccttg cggtgcatgc ttcggcaggc cgactcatcc
    19141 tcgtcaaaga agggactccc atgctggtaa atcatgatgc cgtcttcctt cagagctcga
    19201 taactattgc cgtagaattc cttggtaaag agtccttccg tatggccaaa tggatctgtc
    19261 gcatcgttga tgataatatc atagtcatct tcgcagtttc gcaaaaagcg tagcccattt
    19321 tggtagtaaa tagtaacacg aggatcatct aggcctgcag caaagtctgg gaaatactca
    19381 cgacagacct cgaccaacat ctcatccggt tccacgatat cgatttgttc cagttcagga
    19441 tagagtgtta atacttgggc aacaccgccg tcaccacccc caataaccaa tactttcttt
    19501 ggatttgggt ggacagccat gggaacgtgg acggtcattt cattgtagac gaaatcatcc
    19561 gcatctgaga acaagacatg gccatttaaa atcagtattt tcccaaaagc tggcgtatcc
    19621 aagacttcga tatcctgcca ttcacttttt ccagcgtaaa gttgcttggc tgttctcaga
    19681 gacaatttga catctggagt atgaacttca gaaaaccata aatccatcta tttctcctta
    19741 tattatattt agcgcagtta gctactgcca aagcccaagt ggtatacttg gaataagcca
    19801 ctgtggatta gttcatttcc tccaatcgct tgacgatttc ctaaaggctc taaccacagc
    19861 tttttgtttc aattggtaat gagtttgata acgcatagac gttttatctc gtctaaggta
    19921 acagggcaaa aagttcgtgg ataaccaagt agacttgaaa tactacatct ggaggtactc
    19981 ccatgcctta tgtgggcatt gatgtcgcta aaaataaaca cgatgttaca gccttgaatg
    20041 ttcaaggaaa aactgttctt aaaccactca ctttttcaaa taataaagct ggttttgaac
    20101 tcttagatct gtctcttcga cagctcaacc aagactgtct catcgctctt gaagatactg
    20161 gacattatgc ctttaatcta ctgaacttcc tgcatgaaca aggatataaa gtttacacct
    20221 acaatccttt gctcatcaag aaatttgcca aatcattatc acttcgcaag actaaaacgg
    20281 ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat
    20341 ttcaacacaa taatcggcaa gtagaactaa aaatactgac tagacatatt catcgtctca
    20401 agaaaaaaca gtctgattgg aaagtacaat acactcgttg ccttgatatc atctttcctg
    20461 agttggataa aatcgttgga aagcattcag aatataccta ccaactcttg acacgctacc
    20521 ctaatcctca gaaaaggatt gaggcaggat ttgataagct gatagaaatt aagcgattga
    20581 ccgcttctaa ttcaagggct ttttgccgtg ctctaaaatc atcgccaaat catcaaattg
    20641 aaataagaaa tagtttagat aaactattga cttttcttat agtttgtctt tctcttaata
    20701 acgttgatat gattgacctc tggatcttcc gtcccttgga gggagcaacc acgttccttg
    20761 gcgaattgga tatagtcgac aatttctcgt gtaatgcgtt caccaggagc caagatagga
    20821 atacctggag ggtaacacat aacaaattct ccacagacct gtccaacaga atcatccaaa
    20881 gttaaacttt ttctttctga atagaaggct tcttgcggag acagcactaa ctcgggctga
    20941 atatattctc ctgctatcaa atcttttcca tctcttgaat agagtctctt aatatcagcc
    21001 agagcaccaa ccaagcgctc gatgtcttgg atgcggtcgc cgatggaaat ataggccaag
    21061 atattgccga tatcaccaaa ctcgatctga atgtcgtatt cgtctcgcaa gaggtcataa
    21121 acctcgatac ctgttaagcc aataccctga gtgtaaactg acaacttagt tacgtcaaaa
    21181 tcgcaaaccg aaacaccgtc tattaactct tttgagtagg catagtagcc accgatagca
    21241 ttgatttcac ggcgggcata ctcagatagc tcaatgactt cctcaaacga ctctttacca
    21301 cgaagggcca agttgcgacg tgaaatatcc aaactagcca tcaacaagta agaggcagat
    21361 gtagactggg tcaggttaat tatctgacga acgtattcag aattcatctg ctccccgata
    21421 agtaaaatgg agctttgggt caaactccca ccagacttat gcatggaaac tgctgccata
    21481 tcagcccctg catccatagc agaaattgga agtttatcag tgaaatgcaa atgcgctccg
    21541 tgggcttcat ctactaaaac catcatgcca gcttcatgag ccatttctgt caaccccttt
    21601 aggtctgaac agatgccgta gtaagtagga ttgttgatta ggatagcctt agcatctgga
    21661 tggtccttta tggcctgtgc tactcggtca ttttcaagac ctaaagcgat accaatctta
    21721 ggatctacac tcatctcgat atagatggga atggcaccac atagaaccaa cgcattgata
    21781 gcagatttat ggacatttcg tggcagaata atcttatctc ctgccttgca ggttgccaga
    21841 atcatagtct gcaccgatga agttgttcca ccaatcatta gaaaggcatg gctagctcca
    21901 aaagcatctg cagccagctc ctctgcatca cgaataatcg aaataggatg gcctaaatta
    21961 tccaagggtt tcatcgaatt gacatcaatg cctacacatt tttctcctaa gagttcgaca
    22021 agttctggat ttccccgtcc acgcttgtga cctggaacat caaagggaac aatccttttc
    22081 ttgcgcaact tcaccaaggc ctcataaatt ggggcttggt tttgatctaa ctctttcaaa
    22141 acatactcct ttcaatattt ttaggacctt atgaaaacta aggaactaaa ggttgactca
    22201 tgaaaaaaga gcaggttttc acctgctctg caatcttctg acgtgtttat tttggtttct
    22261 gttgagtatg tctgttcccg atgtttccta actctctagt agcaaatatt acgtacttta
    22321 ttgatcgttt cacaagatga cgtgtgcttt caccacacta aaaatttatg aattaggaca
    22381 agtgtcctaa catcaactta taaaagtagg cttttaaccc tatcaataat gtggcttttc
    22441 aaccacgctt cggcattcaa ccctgcctgt ccgtaggcat tttttactcg ggtttatatt
    22501 tgctagaaaa catcatctca ttttctaagc tttattacta tatcatgttt ttaagaactt
    22561 gtaaagtatt ttttgataaa aa
//
LOCUS       DAVLCS010000033        22133 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLCS010000033 DAVLCS010000000
VERSION     DAVLCS010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22133
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.033"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            1..267
                     /locus_tag="VXC78_001499"
     CDS             1..267
                     /locus_tag="VXC78_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000962022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGC"
                     /protein_id="HEV0583555.1"
                     /translation="MLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAEL
                     YSLEKNEDASLSKLQADGRITEEQAKAYKEYHDKNGVANRKVND"
     gene            260..664
                     /locus_tag="VXC78_001500"
     CDS             260..664
                     /locus_tag="VXC78_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV0583556.1"
                     /translation="MIKAFTMLESLLALSLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLPVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            669..929
                     /locus_tag="VXC78_001501"
     CDS             669..929
                     /locus_tag="VXC78_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583557.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            892..1353
                     /locus_tag="VXC78_001502"
     CDS             892..1353
                     /locus_tag="VXC78_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0583558.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRFYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            1331..1744
                     /locus_tag="VXC78_001503"
     CDS             1331..1744
                     /locus_tag="VXC78_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0583559.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKKSEEKPEKKENS"
     gene            1881..2474
                     /locus_tag="VXC78_001504"
                     /pseudo
     CDS             1881..2474
                     /locus_tag="VXC78_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            2535..3488
                     /locus_tag="VXC78_001505"
     CDS             2535..3488
                     /locus_tag="VXC78_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0583560.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGETEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            3539..4729
                     /locus_tag="VXC78_001506"
     CDS             3539..4729
                     /locus_tag="VXC78_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV0583561.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            4878..5249
                     /gene="rnpA"
                     /locus_tag="VXC78_001507"
     CDS             4878..5249
                     /gene="rnpA"
                     /locus_tag="VXC78_001507"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV0583562.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            5224..6048
                     /locus_tag="VXC78_001508"
     CDS             5224..6048
                     /locus_tag="VXC78_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0583563.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            6067..7053
                     /locus_tag="VXC78_001509"
     CDS             6067..7053
                     /locus_tag="VXC78_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV0583564.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVNAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     ANRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            7104..7727
                     /locus_tag="VXC78_001510"
     CDS             7104..7727
                     /locus_tag="VXC78_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV0583565.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQCLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            7868..9325
                     /locus_tag="VXC78_001511"
     CDS             7868..9325
                     /locus_tag="VXC78_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0583566.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDREKYYNGEVQEEA"
     gene            9348..9629
                     /locus_tag="VXC78_001512"
     CDS             9348..9629
                     /locus_tag="VXC78_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0583567.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            9705..10190
                     /locus_tag="VXC78_001513"
     CDS             9705..10190
                     /locus_tag="VXC78_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0583568.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            10207..10872
                     /locus_tag="VXC78_001514"
     CDS             10207..10872
                     /locus_tag="VXC78_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV0583569.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            10876..11739
                     /locus_tag="VXC78_001515"
     CDS             10876..11739
                     /locus_tag="VXC78_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV0583570.1"
                     /translation="MVRPIGIYEKATPTHCTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            11741..12445
                     /locus_tag="VXC78_001516"
     CDS             11741..12445
                     /locus_tag="VXC78_001516"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV0583571.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            12622..14295
                     /locus_tag="VXC78_001517"
     CDS             12622..14295
                     /locus_tag="VXC78_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0583572.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            14407..15498
                     /gene="ulaG"
                     /locus_tag="VXC78_001518"
     CDS             14407..15498
                     /gene="ulaG"
                     /locus_tag="VXC78_001518"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV0583573.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNSKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            15612..17588
                     /gene="tkt"
                     /locus_tag="VXC78_001519"
     CDS             15612..17588
                     /gene="tkt"
                     /locus_tag="VXC78_001519"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0583574.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVISMPSTDVFDKQNAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            17705..18004
                     /gene="yajC"
                     /locus_tag="VXC78_001520"
     CDS             17705..18004
                     /gene="yajC"
                     /locus_tag="VXC78_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0583575.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            18050..18478
                     /locus_tag="VXC78_001521"
     CDS             18050..18478
                     /locus_tag="VXC78_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV0583576.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            18480..18890
                     /locus_tag="VXC78_001522"
     CDS             18480..18890
                     /locus_tag="VXC78_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583577.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            19190..21841
                     /gene="adhE"
                     /locus_tag="VXC78_001523"
                     /gene_synonym="adhC"
     CDS             19190..21841
                     /gene="adhE"
                     /locus_tag="VXC78_001523"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV0583578.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELSFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT         6950 a         3981 c         4840 g         6362 t
ORIGIN      
        1 atgttggtgg tcttgctgat tatcagcgtg cttttcttgc tctttgtacc taatctgacc
       61 aagcaaaaag aggcagtcaa tgacaaagga aaagcagctg ttgttaaggt ggtggaaagc
      121 caggcagaac tttatagctt ggaaaagaat gaagatgcta gcctaagcaa gttacaagca
      181 gatgggcgaa tcacggaaga acaggctaaa gcttataaag aataccatga taaaaatgga
      241 gtagcaaatc gtaaagtcaa tgattaaggc ctttaccatg ctggaaagtc tcttggcttt
      301 gagtcttgtg agtatccttg ccttgggctt gtccggctct gttcagtcca cttttgcggc
      361 agtagaggaa cagattttct ttatggagtt tgaagaactc tatcgggaaa cccaaaaacg
      421 cagtgtagcc agtcagcaaa agactagtct gaacttagat gggcagacgc ttagcaatgg
      481 cagtcaaaag ttgccagtcc ctaaaggaat tcaggcccca tcaggtcaaa gtattacatt
      541 tgaccgtgct gggggcaatt cgtccctggc taaggttgaa tttcagacca gtaaaggagc
      601 gattcgctat caattatatc taggaaatgg aaaaattaaa cgcattaagg aaacaaaaaa
      661 ttagggcagt gattttactg gaagcagtag tcgctctagc tatctttgcc agcattgcga
      721 ccctcctttt gggacaaatt caaaaaaata ggcaagagga agcaaaaatc ttgcaaaagg
      781 aagaagtctt gagggtagct aagatggccc tgcagacggg gcaaaatcag gtaagcatca
      841 acggagttga gattcaggta ttttctagtg aaaaaggatt ggaggtctac catggttcag
      901 aacagttgtt ggcaatcaaa gagccataag gtcaaggctt ttaccttgtt agaatccctg
      961 cttgccctca ttgtcatcag tgggggatta ctcctttttc aagctatgag tcagctcctc
     1021 atttcagaag ttcgctacca gcaacaaagc gagcaaaagg agtggctctt gtttgtggac
     1081 caacttgagg tagaattaga ccgttcgcag ttcgaaaaag tggaaggcaa tcgtttctat
     1141 atgaagcaag atggcaagga catcgccatc ggtaagtcaa agtcagacga ttttcgtaaa
     1201 accgatgcta gtggacgggg gtatcagcct atggtttatg gcctcaaatc agctcagatt
     1261 acagaggaca atcaactggt tcattttcgt ttccagtttc aaaaaggctt agaaagggag
     1321 ttcatctatc gtgtggaaaa agaagaaagt taaggcaggt gttctcctct atgcagtcac
     1381 catggcagct atctttagtc ttttgttgca attttacttg aaccgacaag tcgcccacta
     1441 tcaagactat gctttgaata aagaaaaatt ggttgctttt gccatggcta aacgaaccaa
     1501 ggataaagcc gagcaagaaa gtggggaaca ggtctttaat ctaggtcagg taagctatca
     1561 aaacaagaaa acaagcttgg tgacgactgt tcgtacggat aagagtcaat atgagtttct
     1621 gtttccttca gtcaaaatca aagaagagaa aagagataaa aaggaagagg tagcgactga
     1681 ttcaagcgaa aaagcggaga agaaaaaatc agaagagaag cctgaaaaga aagagaattc
     1741 ctagtcaatt caactataat gcgttgaatc caaaatagtc cactgtagtt tctagaaaat
     1801 tgctggaaat ggatgttaag ctccaattca tttgtttata tcttatttca gtttactata
     1861 ctttgtgcta aactaaagat atgaaacatg attttaacca caaagcagaa actttcgatt
     1921 cccctaaaaa atcttcctcg caaacttggt atgtcaagca gccgagaaac agattgatct
     1981 tctatcagac aaagaaattt tagatttcgg tggtggcacg gatctattag ccttgcccct
     2041 agcccctagc caagcaggct aagtcagtca ctcttgtaga catttctgag aaaatgttgg
     2101 agcaagctcg tttgaaagtg gagcagcaag caatcaagaa tatccagttt ttggagcaag
     2161 atttaccgaa aaatcccttg gagaaagagt ttgattgcct tgctgttagt cgggttcttc
     2221 atcatatgcc tgatttggat gcggctctct cactgtttca tcaacatttg aaggaagatg
     2281 ggaaactcat cattgctgat tttaccaaga cagaagctaa tcatcatgga tttgatttag
     2341 ctgaactgga aaacaagcta attgagcatg gtttttcatc tgtgcatagt cagattctct
     2401 atagcgctga agacctgttt caaggaaatc actcagaatt ctttttaaca gtagcccaaa
     2461 aatcactcgc ctagtcaggg agtgattttt ctataaggat ggaaaaaaga agggaaattt
     2521 ggtaagatag taatatggat tttgaaaaaa ttgaacaagc ctatacctat ttactagaga
     2581 atgtccaagt catccaaagt gatttggcga ccaactttta tgacgccttg gtggagcaaa
     2641 acagcatcta tctggatggt gaaactgagc taaaccaggt caaagacaac aatcaggccc
     2701 ttaagcgttt agcactacgc aaagaagaat ggctcaagac ctaccagttt ctcttgatga
     2761 aggctgggga aacagaaccc ttgcaggcca atcaccagtt tacaccagat gccattgctt
     2821 tgcttttggt gtttattgtg gaagagttgt ttaaagagga ggaaattact atcctcgaaa
     2881 tgggttctgg gatgggaatt ctaggcgcta ctttcttgac ctcgcttgat aaaaaggtgg
     2941 attacttggg aatggaagtg gatgatttac tgattgatct ggcagctagc atggcagatg
     3001 taattggttt gcaggctggc tttgtccaag gagatgccgt tcgtccacaa atgctcaaag
     3061 aaagcgatgt ggtcatcagt gacttgcctg tcggctatta tcctgatgat gccgttgcgt
     3121 cgcgtcatca agttgcttct agccaagaac atacttacgc ccatcacttg ctcatggaac
     3181 aagggtttaa gtacctcaag tcagatggat atgctatttt tctagctccg agtgatttgt
     3241 tgaccagtcc tcaaagtgat ttgttgaaag tctggttgaa agaggaggca agtctggttg
     3301 ctatgattag tttacctgaa aatctctttg ctaatgccaa acaatctaag actattttta
     3361 tcttacagaa gaaaaatgaa atagcagtag agccttttgt ttatccactt gctagcttgc
     3421 aagatgcaag tgttttaatg aaatttaaag aaaattttca aaaatggact caaggtactg
     3481 aaatataaaa tagattttgt tataatagtt gaaaacgctt aaaaaggggt atcatgttat
     3541 gacaaaaaca attgcaatca atgcaggaag ttcaagtttg aaatggcaat tatacttaat
     3601 gccagaggaa aaagtgttag ccaaaggttt gattgaacgt atcggtttga aagattcaat
     3661 ttcaactgta aaatttgacg gccgttctga acaacaaatt ttggatatcg aaaatcatac
     3721 acaagccgtt aaaattttat tggatgactt gattcgtttc gatattatca aggcttatga
     3781 cgagattaca ggtgttggac atcgtgttgt tgctggtgga gaatatttca aagaatcaac
     3841 agttgttgag ggagatgttt tagaaaaagt tgaagagttg agtttgttgg ctcctctaca
     3901 caacccggcc aatgcagcag gtgttcgtgc cttcaaggaa ttgttgccag acattaccag
     3961 tgtagttgtt tttgatactt ccttccacac aagtatgcca gagaaagctt atcgctaccc
     4021 tctaccaaca aaatattaca cagaaaacaa ggttcgtaaa tacggtgctc atggtacaag
     4081 tcaccagttt gtagcaggag aagctgcaaa actcttggga cgtccattag aagacttgaa
     4141 gttaattacc tgtcatattg gtaacggagg ctcaattaca gctgtgaaag ccggcaaatc
     4201 tgtagacact tctatggggt tcactcctct tggtggtatt atgatgggaa cgcgtacagg
     4261 ggatattgat ccagctatca ttccttattt aatgcaatat acagaggatt ttaacacacc
     4321 agaagatatc agtcgtgttc ttaaccgtga atcaggtctt ttgggagttt ctgctaattc
     4381 tagcgatatg cgcgatatag aagcagctgt agcagaaggg aatcacgagg ctagcttggc
     4441 ttatgaaatg tatgttgacc gtatccaaaa acatatcggt cagtaccttg cagtgctaaa
     4501 tggagcagat gccattgttt tcacagcagg tgtcggtgaa aatgcagaga gtttccgtcg
     4561 tgatgtaatc tcagggattt cgtggtttgg ttgtgatgtt gatgatgaaa agaatgtctt
     4621 tggcgttaca ggagacatct caacagaggc agctaaaatc cgtgtcttgg ttattccaac
     4681 agatgaagaa ttagtcattg cccgtgacgt tgaacgcttg aaaaaataag tgaaactaaa
     4741 aaaatattca atacaaggag ttgggaaagt tatttttcca gcttcttttt ctgatgaaat
     4801 tgtccaaaac cttgctatga ttggcttttt tgaaaaatat ggtataatag tagtaattta
     4861 atagatggag ttgagttttg aagaaaaact ttcgtgtaaa aagagagaaa gattttaagg
     4921 cgattttcaa ggaggggaca agttttgcta atcgcaaatt tgtggtctac caattagaaa
     4981 accagaaaaa ccattttcga gtaggtctat cagttagcaa aaaactgggg aatgccgtca
     5041 ctagaaatca aattaagcga cggattcggc atattatcca gaatgcaaaa gggagtctgg
     5101 tagaagatgt cgactttgtt gtcattgctc gaaaaggagt cgaaaccttg ggatacgcag
     5161 agatggagaa aaatctactc catgtattaa aattatcaaa gatttaccgg gaaggaaatg
     5221 ggagtgaaaa agaaactaaa gttgactagt ttgctaggac tgtctctgtt aatcatgaca
     5281 gcctgtgcga ctaatggggt aactagcgat attacagccg aatcggctga tttttggagt
     5341 aaattggttt acttctttgc ggaaatcatt cgctttttat cgtttgatat tagtatcgga
     5401 gtggggatta ttctctttac ggtcttgatt cgtacagtcc tcttgccagt ctttcaggtg
     5461 caaatggtgg cttctaggaa aatgcaggaa gctcagccac gcattaaggc gcttcgagaa
     5521 caatatccag gtcgagatat ggaaagcaga accaaactag agcaggaaat gcgtaaagta
     5581 tttaaagaaa tgggtgtcag acagtcagac tctctttggc cgattttgat tcagatgccg
     5641 gttattttgg ccctgttcca agccctatca agagttgact ttttaaagac aggtcatttc
     5701 ttatggatta accttggtag tgtggataca acccttgttc ttccgatttt agcagcagta
     5761 ttcacctttt taagtacttg gttgtccaac aaagctttgt ctgagcgaaa tggcgctacg
     5821 actgcgatga tgtatgggat tccagtcttg atttttatct ttgcagttta tgcgccaggt
     5881 ggagtcgccc tatactggac agtgtctaat gcttatcaag tcttgcaaac ctatttcttg
     5941 aataatccat tcaagattat cgcagagcgc gaggccgtag tacaggcaca aaaagatttg
     6001 gaaaatagaa aaagaaaagc caagaaaaag gctcagaaaa cgaaataaat aaggaggaat
     6061 ctggtaatgg tagtatttac aggttcaact gttgaagaag caatccagaa aggattgaaa
     6121 gaattagata ttccaagaat gaaggctcat atcaaagtca tttctaggga gaaaaaaggc
     6181 tttcttggtc tatttggtaa aaaaccagcc caagtggata ttgaagcgat tagtgaaacg
     6241 actgttgtca aagcaaatca acaggtagta aaaggcgttc cgaaaaaaat caatgatttg
     6301 aacgagcctg tgaagacggt tagtgaagaa accgttgacc ttggtcatgt ggttaatgct
     6361 attaaaaaaa tagaggaaga aggtcaaggt atttctgatg aagtcaaggc tgaaatctta
     6421 aaacatgaaa gacatgccag cactatctta gaagaaactg gtcacattga gattttaaat
     6481 gaacttcaaa tcgaggaagc gatgagggaa gaagcaggcg ctgatgacct tgaaactgag
     6541 caagatcaaa ctgaaaatca agacttgaaa gagatgggct tgaaggtcga gcaaagttat
     6601 gatattgccc aggtggctac ggatgtgact gcctatgttc aagcgattgt ggatgacatg
     6661 gatgttgaag ctacactttc aaatgattat aaccgtcgta gcatcaatct acaaattgac
     6721 accaacgaac caggtcgtat tatcggctac catggtaaag tcttgaaggc cttgcaactg
     6781 ttggctcaaa attatcttta caaccgctat tccaaaacct tctacgttac aatcaatgtc
     6841 aatgattatg tcgaacaccg tgcagaagtc ttgcagacct atgcgcaaaa attggcgaat
     6901 cgtgttttgg aagaaggtcg cagtcataaa acagatccaa tgtcaaatag cgaacgcaag
     6961 attatccatc gtattatttc acgtatggat ggcgtgacta gttactctga aggtgatgag
     7021 ccaaatcgct atgttgttgt agatacagaa taagtaaaat cagggttgac ctgatttttt
     7081 gctagttaga ggaggttaaa ctgatgttga ataagataag agactatcta gacttttctg
     7141 gtttgcagta ccgtagtcct gataaagcgg gagcagagcg agagaagatg ctggcgttcc
     7201 gccacaaagg acaagaggcc cgaaaggctt ttacagaact ggccaaagcc tttcaagcaa
     7261 gccatccaga atggcaactc caacagacta gtcagtggat gaatcaggcc cagtgtttga
     7321 gaccacattt ttgggtttat ctacagagag acggacaagt gacagaacct atgatggcct
     7381 tacgtttgta tgggacatct actgactttg gaatttcttt ggaagtcagt ttcatcgaac
     7441 gtaagaagga tgagcaaaca ctgggcaagc agaccaaagt tttagacatt ccaaccgtta
     7501 aagggattta ttatctaacc tactctaatg gtcaaagtca acggtgggag gcgaatgaag
     7561 aaaagcgtcg tactttacgc gagaaggtga gaagtcaaga agttcgaaaa gttttagtga
     7621 aggtagatgt tcctatgaca gaaaattcgt ctgaagaaga aatcgtagaa ggcttattga
     7681 agtcttattc taaaattctt ccctattatc tagctacgag aaaataagat aatttgtaaa
     7741 acatcataaa tcatcataaa tcatacagtc caagagtgaa cagtccgctg tgtaattctt
     7801 ggtctttttg tttgcgcttt cgcattatat aataaactta caaaaacaat tcaaaaggag
     7861 aacaattatg gaagtcgttt caagtgttct aaattggttt tctagcaata ttttgcagaa
     7921 tcccgcattt ttcgtaggtt tattggtgtt gataggatat gcacttttga aaaaacctgc
     7981 ccatgacgtt ttttcagggt ttgttaaagc aacagtaggg tatatgttgc ttaacgtggg
     8041 tgctggtggt ttggttacaa cctttcgtcc aatcttagca gctcttaact acaaattcca
     8101 aattggtgca gcggttatcg acccttactt tggacttgct gcagcaaaca acaaaattgc
     8161 agcagagttt ccagattttg ttggaactgc aactacagct ctattgattg gttttggaat
     8221 aaatatcttg ctcgtagctc ttcgaaagat tacgaaggta agaaccctct ttattactgg
     8281 tcacatcatg gtacaacaag ctgcaacagt atctcttatg gttctattct tagtaccaca
     8341 attgcgcaat gcttacggta cagcagcgat tggtatcatc tgtggacttt actgggcagt
     8401 tagttcaaat atgactgttg aggcaactca acgcttgact ggtggtggcg gatttgcgat
     8461 tggtcaccaa cagcaatttg caatctggtt tgtagataaa gtagcaggac gctttggtaa
     8521 gaaagaagaa agtttagaca atcttaaatt acctaagttc ctctcaatct tccacgatac
     8581 agttgttgca tctgctacct tgatgctcgt attcttcgga gccattcttt taatcttggg
     8641 tccagacatt atgtctaata aagaagtcat cacttcagga actctattca atcctgctaa
     8701 acaagatttc tttatgtaca ttatccaaac agcctttacc ttctcagttt acttgttcgt
     8761 tttgatgcaa ggtgtccgaa tgttcgtatc tgagttgaca aacgccttcc aaggtatttc
     8821 aaacaaattg ttgccaggtt cattcccagc ggttgacgtt gcagcttctt atggatttgg
     8881 ttctccaaat gctgtcttgt caggatttac ctttggtttg attggtcaat tgattacaat
     8941 tgtcttgctc atcgtcttta aaaatccgat tcttattatt acaggatttg taccagtgtt
     9001 ctttgacaat gcagccattg cggtctacgc tgataaacgc ggcggatgga aagcggctgt
     9061 tatcctttcc tttatatcag gtgtccttca agttgctcta ggagctcttt gtgtggccct
     9121 tctcgatttg gcatcttatg gtggctacca tggaaatatc gactttgaat tcccatggct
     9181 tggatttgga tatatcttca aataccttgg tattgttggt tatgtacttg tgtgtctctt
     9241 cttgcttgtt attcctcaac ttcaatttgc caaagcaaaa gatagagaga aatattacaa
     9301 cggtgaagtt caagaagaag cttagtatct agaaaaggag aaataaaatg gttaaagtat
     9361 tagcagcgtg cggaaatgga atgggttcat caatggttat caagatgaag gttgaaaatg
     9421 ctctccgtaa gcttaatcaa acagatttta cagtcaattc atgcagtgtc ggtgaagcta
     9481 aaggtttagc agtaggatat gacatcgtaa tcgcttctct tcatttgatt caagaattgg
     9541 aagggcgaac taatgggaag ttaattgggc ttgataactt gatggatgat aaagaaatca
     9601 ccgaaaaact cagtcaagca ctacagtaaa aggttggagg ggctggacag aaactgagag
     9661 ttatcgtttc tgtccttctc cctctttaaa taaaggaggc agatatgaat ttaaaacaag
     9721 ctttaattga caatgactcg atccgactag gtttagaggc taacaattgg aaagaagcag
     9781 tcaaggtagc agtagatccc ttaattgaaa gtggggcaat tttgccagag tattacgatg
     9841 ctatcattga atcgactgaa gagtatgggc cttactatat cttgatgcca ggtatggcta
     9901 tgccccacgc tagacctgaa gctggtgtgc aaagtgatgc cttttcattg attaccttac
     9961 aaaatcctgt tgtattttca gatgggaaag aggtatctgt tttgttggca ctagcagcaa
    10021 caagttcaaa aattcacaca agtgtagcca ttccacaaat tattgccctg tttgaattag
    10081 aagattctat tgcacgttta caggcttgcc agactaaaga agatgtcttg gctatgattg
    10141 aagaatctaa ggatagccct tatctcgaag gattggattt ggaaagttag aaagaggaat
    10201 aaagaaatga caaaaagaat acctaattta caagttgcat tagaccattc agacttgcaa
    10261 ggagcgatta aagcagctgt ttctgttggt caggaagtag atattatcga agctggaact
    10321 gtttgcttgc ttcaagttgg aagtgaactg gctgaagtct tgcgtagcct tttcccagat
    10381 aagattattg tggcagacac aaaatgtgct gatgctggtg gaacagttgc taaaaataat
    10441 gcggttcgtg gagcagactg gatgacttgt atctgttgtg caaccatccc tactatggaa
    10501 gcagctctaa aggctatcaa gactgaacga ggagaacgag gcgaaatcca gatcgagctt
    10561 tatggcgatt ggacttttga acaagctcag ctttggctag atgcaggtat ttcacaagct
    10621 atttatcacc aatctcgtga tgctcttctt gctggtgaaa cttggggtga aaaagacctt
    10681 aataaggtta aaaaactcat tgacatgggc ttccgtgtat ctgtaacagg tggtctagat
    10741 gtagatactc tcaaactctt tgaaggtgtt gatgtcttta cctttatcgc aggtcgtgga
    10801 attacagagg ctgcggatcc agcaggagca gcgcgtgcct tcaaggatga aatcaaacga
    10861 atttgggggt aaatcatggt acgtccaatt ggaatttatg aaaaggcaac cccaacacac
    10921 tgtacttggc tagaacgttt aaattttgcc aaggagttag gctttgattt tgtcgagatg
    10981 tctattgacg aacgtgacga gcgtttagca agacttgact ggagtaagga agaacgcttg
    11041 gaagttgtca aagcaatcta tgaaactggt gttcgtattc cttctatctg tttttcaggc
    11101 catcgtcgct acccattggg ttcaaaagat ccagttctag aggaaaaatc tctagaactc
    11161 atgaaaaaat gtatcgaatt agctcaagac ttgggagttc gtacgattca attagctggt
    11221 tacgatgttt actatgagga aaagtcaccc cagacacgcc aacgttttat caaaaatttg
    11281 agaaaagcct gtgactgggc tgaagaagct caggtggtac ttgctattga aattatggat
    11341 gatcctttca tcaatagcat cgaaaaatat ttggctatag aaaaagagat tgactctccc
    11401 ttcctctttg tatatccaga tattggtaat gtgtctgcat ggcataatga tatctatagt
    11461 gagttttatc ttggtcatca tgccatcgca gctctccatc tcaaggatac ttatgcagtg
    11521 acagaaagtt caaagggcca gttccgagat gtaccttttg ggcaaggttg tgtcaaatgg
    11581 gaagaagctt tcgatatttt aaaggaaacc aattataatg gacctttcct aatcgaaatg
    11641 tggtctgaaa attgtgaaac agtagaagaa acacgcgcag ccattcaaga ggcgcaagct
    11701 tttctctatc cactcattaa gaaagcaggt ttgatgtaag atgaatcaag taatcaatgc
    11761 tatgcgtaaa cgagtttgtg atgccaatca atcattgcca aaacatggac ttgtcaaatt
    11821 tacctggggg aatgtatctg aagtcaatcg cgaactcggt gtcattgtta tcaaaccatc
    11881 aggcgtggat tatgacgaat tgacacctga aaacatggta gtgactgatc tagatggtaa
    11941 gatcctagaa ggggatttaa gaccatcttc cgacctccca actcatgtgc aattatataa
    12001 ggcttggtca gaaattggta gtgtggttca cacccattcg acagaagctg ttggttgggc
    12061 tcaggcaggt cgtgatattc ctttctacgg aacaacccat gcagattatt tctacggttc
    12121 aatcccttgc gcccgtagtt tgaccaagga cgaagtagaa gtggcctatg aaaaagatac
    12181 tggcctggtt atcgtagaag aatttgaaca tcgcggactt aacccggttg aagtaccagg
    12241 aattgttgta cgcaatcacg gtccattcac ctggggcaaa aatccagaga atgctgttta
    12301 tcactctgtc gtactagagg aagtatcaaa gatgaatcgc tttacagaac aaatcaatcc
    12361 aagagttgga cctgctcccc agtacatact agaaaaacac taccaacgta aacatggacc
    12421 aaatgcttat tatggtcaaa agtaagaacg atgaaggagg agaaaaagat aaatttagct
    12481 cctcttttta catttgattt ttattgagag taaagttgga gttgaagtaa ttttgaaaga
    12541 ttttttagaa atagcgcttg atatatatgg taaaataaaa agaattgctg tgatatcaat
    12601 agatttgggg gattttttaa tatggtactg gataaggcaa gttgtgattt gcttcaatat
    12661 ttgatggatc aagaaacgtc caaaacgatt atggcgattt cgaaagattt gaaagagtca
    12721 agaaggaaaa tttattatca cattgacaaa atcaatgctg ctctggttga cgaggcgctt
    12781 cacatcatta gtattccacg aattggtatt cacttaacgg aagagcagag agatgcttgt
    12841 tgtaaactat tatcggaagt agattcgtac gattatatca tgagtgcgca tgaacgtatg
    12901 atgataatgt tactatggat aggtatttct aaagaacgta ttacgattga aaaattgata
    12961 gagttaacag aggtatctag gaatactgtt ctcaatgatt tgaatagtat tcgttatcaa
    13021 ctaactttgg aacaatatca ggtgatcttg caagtgagca agtcacaggg ataccacctt
    13081 catgcccacc ctcttaataa aattcagtat cttcaatcgc ttctatatca tatttttatg
    13141 gaagaaaatg ccacttttgt atctatttta gaagataaga tgaaagagag gttagatgat
    13201 gagtgtttgc tttctgttga aatgaaccaa ttttttaagg aacaggttcc tttagttgaa
    13261 caagatttag ggaagaaaat aaaccatcat gaaataactt ttatgttgca ggttctacct
    13321 tatttgctgt taagctgtca taatgttgaa cagtatcaag aaagacatca ggatatagag
    13381 aaagaatttt ctttgataag aaaaagaata gagtatcagg tgtctaagaa attaggagaa
    13441 cggttgtttc aaaagtttga aatttctttg tcaggacttg aagtttctct tgtagctgtt
    13501 ctcctcctct cctatcgtaa ggatttggat attcatgcag aaagtgatga ttttcggcaa
    13561 ttaaaacttg ctttagaaga atttatctgg tattttgaat cacaaatccg aatggagatt
    13621 gagaacaagg atgatttgtt acgaaatttg atgatccact gtaaagcctt gttatttaga
    13681 aagacttacg gtattttttc taaaaatcct ctaacaaaac aaattcgatc caagtatgga
    13741 gaattatttt tagtcactag aaaatctgcg gaaattttag aaggagcatg gtttattcgg
    13801 ctaacagacg atgatattgc ctatttgacg attcatattg gaggattttt aaagtataca
    13861 ccatcgtctc aaaaaaatat gaaaaaagtt tatctcgttt gtgatgaagg tgttgcggtt
    13921 tcgagacttt tgctgaaaca atgcaaactt tattttccaa atgagcaaat tgacactgta
    13981 tttacaacag aacaatttaa gagtgtggaa gatattgcac aagttgatgt agtgattact
    14041 actaatgatg atttggatag cagatttccg attttaaggg ttaatcctat ccttgaagca
    14101 gaagatattt tgaaaatgct agactatctt aaacacaata tatttcgtaa taagagcaaa
    14161 agtttcagtg aaaatctttc tagtcttatt tcgtcttata ttgtagacag caagttggct
    14221 agtaagttcc aagaagaggt tcaaacactt ataaatcaag aaatagtagt tcaagctttt
    14281 ttggaagata tttgaaggac agtccaatga tgaacacaaa cctgtgtttt tcttggtctt
    14341 ttttagtgtt ttgaagggtg gtatactaat ctcaaagata acaattatat ccaaaggagg
    14401 caacatatgc caaacgtcaa agaaattaca agagagtcat ggattttagc cactttccca
    14461 gagtggggaa catggttgaa cgaagaaatc gaagaagaag tcgtacctga aggcaatttt
    14521 gccatgtggt ggctaggcaa ctgtggtact tggattaaga caccagctgg tgctaacgtt
    14581 gtcatggacc tttggtcaaa ccgtggaaaa tcaaccaaaa aagtgaaaga tatggttcgt
    14641 gggcaccaaa tggcaaatat ggcaggtgtt cgtaagttgc aaccaaactt gcgtgttcag
    14701 ccaatggtta tcgatccatt tgctatcaac gaactagact attacttagt ttcacacttc
    14761 cacagtgatc atatcgaccc atacacagct gcagcaattc tcaacaattc taagttagag
    14821 catgttaagt ttatcggtcc ttaccactgt ggacgaatct gggaaggatg gggtgttcca
    14881 aaagaacgta tcatcgttgt taaaccaggt gacactatcg aattaaaaga tatgaagatt
    14941 catgcagtag aatcatttga ccgtacttgc ttggtaactc tcccagtgaa cggtgctgat
    15001 gagacaggcg gtgaacttgc tggcttggct gttacagatg aagaaatggc tcaaaaggct
    15061 gttaactata tctttgaaac accaggtgga accatctatc atggtgcaga ttctcacttc
    15121 tcaaactatt ttgcaaaaca tggtaaagac tttaaaattg atgttgcttt gaataactat
    15181 ggtgaaaatc cggtaggtat ccaagacaaa atgacatcta tcgatcttct tcgtatggca
    15241 gaaaatctgc gtaccaaagt cattatccca gttcactatg atatctggtc taacttcatg
    15301 gcttctacta atgagattct agaactttgg aaaatgcgaa aagatcgctt gcaatacgat
    15361 ttccatccat ttatctggga agttggcggt aagtacactt atcctcaaga tcaacactta
    15421 gtagaatacc atcatccacg tggttttgat gattgttttg aacaagactc taacattcaa
    15481 tttaaagctt tgctataata taaaaatatt ctttggaggt tatccgtatg ttgcatgata
    15541 cggataattt tcatataata gtaaaataga atgtgtgatt caataatcac ctcaaataga
    15601 aaggaaattc tatgtcaaat ctatctgtta atgcaattcg ttttctaggt attgacgcca
    15661 ttaataaagc caactcaggt catccaggtg tggttatggg agcggctccg atggcttaca
    15721 gcctctttac aaaacaactt catatcaatc cagctcaacc aaattggatt aaccgcgacc
    15781 gctttattct ttcagcaggt catggttcaa tgctccttta tgctcttctt cacctttctg
    15841 gttttgaaga tgtcagcatg gatgagatta agagtttccg tcaatggggt tcaaaaacac
    15901 caggtcaccc agaatttggt catacggcag ggattgatgc tacgacaggt cctctagggc
    15961 aagggatttc aactgctact ggttttgccc aagcagaacg tttcttggca gccaaatata
    16021 accgtgaagg ctacaatatc tttgaccact atacttacgt tatctgtgga gacggagact
    16081 tgatggaagg tgtctcaagc gaggcagctt catacgcagg tttgcaaaaa cttgataagt
    16141 tggttgttct ttatgattca aatgatatca acttggatgg tgagacaaag gattccttta
    16201 cagaaagtgt tcgtgaccgt tacaatgcct acggttggca tactgccttg gttgaaaatg
    16261 gaacagactt ggaagccatc catgctgcta tcgaaacagc aaaagcttca ggcaagccat
    16321 ctttaattga agtgaagacg gttattggat atggttctcc aaacaaacaa ggaactaatg
    16381 ctgtacacgg cgcccctctt ggagcagatg aaactgcatc aactcgccaa gccctcggtt
    16441 gggactacga accatttgaa attccagaac aagtatatgc tgatttcaaa gaacatgttg
    16501 cagaccgtgg cgcatcagct tatcaagctt ggactaaatt agttgcagat tataaagaag
    16561 ctcatccaga actggctgca gaagtagaag ccatcatcga cggacgtgat ccagtcgaag
    16621 tgactccagc agacttccca gctttagaaa atggtttttc tcaagcaact cgtaattcaa
    16681 gtcaagatgc cttgaatgtt gtggcagcta aattaccaac cttcctaggt ggatcagctg
    16741 accttgctca ctcaaacatg acttatatca agacggatgg acttcaagac gataccaatc
    16801 gcttgaatcg taacattcag tttggtgttc gtgaatttgc aatgggaaca atcttgaacg
    16861 ggatggccct tcatggtgga cttcgtgtat acggtggaac tttcttcgtc ttctctgact
    16921 atgtgaaggc agctgtccgc ttgtcagcct tacaaggact tcctgtgact tatgtcttta
    16981 cccatgattc aatcgcagtt ggggaagatg gtccgactca cgaaccagtt gagcatttag
    17041 caggtcttcg tgctatgcca aatctaaatg ttttccgtcc agcagatgcg cgtgaaacgc
    17101 aagcagcttg gtaccttgca gtgacaagtg agaaaacacc aactgccctt gtcttgacac
    17161 gtcaaaactt gactgttgaa gatggaacag acttcgacaa ggttgctaaa ggtgcttatg
    17221 ttgtatatga aaatgcagcc gactttgata ccatcttgat tgcgacaggt tcagaggtta
    17281 atcttgctgt ctcagctgct aaagaattgg ctagtcaagg cgaaaaaatc cgcgtaatca
    17341 gcatgccatc tacagatgtc tttgataaac aaaatgcagc ttacaaggaa gagattcttc
    17401 caaatgcagt ccgccgtcgt gttgcagtcg aaatgggtgc aagtcaaaac tggtacaaat
    17461 atgttggtct cgatggtgcc gttctaggta ttgatacctt cggagcctct gccccagcac
    17521 caaaagtatt ggcagaatat ggctttactg tcgaaaatct tgtaaaagtt gttcgaaatt
    17581 tgaaataatc ctaaaaatca gggcgtaagc tctggttttt cttaccagaa aagtaaggta
    17641 caatcttgta aaagtagctg aaatttgata tagtagtcct atgtaaaaga caaaggagaa
    17701 aacaatgaat ccaaatatta cttttttaat catgcttgta ggtatgatgg ccttgatgtt
    17761 ctttatgcaa cgttctcaaa agaaacaagc tcaaaagcgt atggaaagct taaataaact
    17821 acaaaaaggc tatgaagtga ttacaatcgg tggactttat ggaacagtcg atgaagtaga
    17881 tacggagaag ggaacaatag ttcttgacgt agatggagtt tacttgactt ttgaactagc
    17941 tgctatcaag acagtattac cgctgaaaga aacagcttca ctagaaggcg caattgaaaa
    18001 ataagacggg atcacgaact cccgttttct ataaaagaaa ggaaatggga tgaaaaaatt
    18061 agtctttgtc tgtctgggaa atatttgccg tagccctatg gccgagtttg ttatgaaatc
    18121 aatgacagat aactacgaaa tccaaagtcg agcaacttcc tcttgggaac atggcaatcc
    18181 gattcataag gggactcagg gaatttttca agagtatgag attccttatg acaagaacaa
    18241 gacatcgctt cagattagta aggaagattt tgaagccttt gattatatta tcggaatgga
    18301 cgcttcaaat atttctgact tacgtcagat gtgtccagta gactgtcaag ataagattta
    18361 ctcattttca tctgaaagtg ttccagaccc ttggtataca ggagattttg aagaaaccta
    18421 tcgacgtgtt caagagggct gtcaagcttg gttagaacgt ttagaaaagg agagttaagg
    18481 tggaaaatct tacgaatttt tacgaaaagt atcgtgtcta tctgactcgt ccacgtttag
    18541 agcttttggc agtagttacc attgttttct gtgctgtact cgtctttttt ctaaatattc
    18601 caggaaaagg tgtcttaaaa ctcgataatg gaacgattgt ttatgatggc agtcttgtcc
    18661 gtggtaaaat gaatggccaa ggtaccatta ccttccaaaa tggagaccaa tatacaggtg
    18721 gcttcaacaa tggagccttc aacggaaaag gtacctttca atctaaagaa ggctggacct
    18781 acgaaggtga ttttgtaaat ggtcaggctg aaggaaaagg gaaactaaca acagaacaag
    18841 aagtcgttta tgaaggaact tttaaacaag gcgtttttca acaaaaataa agcctcctta
    18901 tcaaaggagg tattattaga atcacaaggt aagcgcttac ctgtaaatcc ctttctttcc
    18961 aaatccctct tccaagcaag tttgtgaaat aaaaaatatt tgaaataaat ttcacaaact
    19021 tcaaagataa aacttgataa gaaaagaaaa tgagaaaagt ttcacaagag tttaaaaatt
    19081 ctttgtgaaa tgtttatgaa actgtttaca aagttgaaat aatgcgttat aataaacttg
    19141 tgaaaaaatt aacaaaggat atcgttcctt gaaagctatg gaggaaaata tggctgataa
    19201 aaaaactgtg acaccagagg aaaagaaact cgttgctgaa aaacacgtag atgagttggt
    19261 tcaaaaagct ctagttgccc ttgaagaaat gcgtaaattg gatcaagaac aagttgacta
    19321 catcgttgcc aaagcatcag tagcagcttt ggatgcccac ggagaattgg ctttacatgc
    19381 ctttgaagaa acaggacgtg gtgtatttga agacaaagca actaagaact tgtttgcttg
    19441 tgaacacgta gtaaacaata tgcgccacac taagacagtt ggcgttatcg aagaagacga
    19501 tgtaacagga ttgactctta ttgctgaacc agttggtgtt gtttgtggta ttactccaac
    19561 aacaaaccca acatcaacag caatcttcaa atcattgatt tcattgaaga cacgtaaccc
    19621 aatcgtcttt gccttccatc catcagcaca agaatcatct gctcatgcag ctcgtatcgt
    19681 ccgcgatgca gctatcgcag ctggtgctcc tgaaaactgt gtgcaatgga ttactcaacc
    19741 atctatggaa gcaacaagtg cccttatgaa ccacgaaggt gttgcgacaa tccttgcaac
    19801 aggtggtaat gccatggtta aggcggctta ttcatgtggt aaaccagctc ttggggtagg
    19861 tgccggaaac gttccagctt atgttgaaaa atcagcaaac attcgtcaag cagcacacga
    19921 tatcgtcatg tctaaatcat ttgataacgg tatggtctgt gcatctgaac aagcagttat
    19981 cattgataaa gaaatttacg atgaatttgt agcagagttc aaatcttacc acacttactt
    20041 tgtaaacaaa aaagaaaaag ctcttcttga agagttctgc ttcggcgtca aagcaaacag
    20101 caaaaactgt gctggtgcaa aattgaacgc tgacatcgtt ggtaaaccag caacttggat
    20161 tgcagaacaa gcaggattta cagttccaga aggaacaaac attcttgctg cagaatgtaa
    20221 agaagttggc gaaaatgagc cattgactcg tgaaaaattg tcaccagtta ttgcagtttt
    20281 gaaatctgaa agccgtgaag atggtattac taaggctcgt caaatggttg aatttaacgg
    20341 tcttggacac tcagcagcta tccacacagc tgacgaagaa ttgactaaag aatttggtaa
    20401 agctgttaaa gctattcgtg ttatctgtaa ctcaccttct acttttggtg gtatcgggga
    20461 cgtttacaat gccttcttgc catcattgac acttggatgt ggttcttacg gacgcaactc
    20521 agttggggat aacgttagtg ccattaacct cttgaatatc aaaaaagtcg gaagacggag
    20581 aaataacatg caatggatga aacttccttc aaaaacatac tttgaacgtg attcaattca
    20641 ataccttcaa aaatgtcgtg acgttgaacg tgtcatgatc gttactgacc atgccatggt
    20701 agagcttggt ttccttgatc gtatcatcga acaactggac cttcgtcgca ataaggttgt
    20761 ttaccaaatc tttgcggatg tagaaccgga tccagatatc acaactgtaa accgtggtac
    20821 tgagattatg cgtgccttca aaccagatac catcatcgca ctcggtggtg ggtctccaat
    20881 ggatgctgcc aaagtaatgt ggctcttcta cgagcaacca gaagtggact tccgtgacct
    20941 tgtccaaaaa ttcatggata tccgtaaacg tgccttcaag ttcccattgc ttggtaagaa
    21001 gactaaattc atcgcgattc caactacatc tggtacagga tctgaagtaa caccatttgc
    21061 cgttatctct gataaagcaa acaaccgtaa atacccaatc gctgactact cattgacacc
    21121 aactgtggca atcgtagacc ctgctttggt attgacagtt ccaggatttg ttgctgctga
    21181 tactggtatg gacgtattga ctcacgcgac agaagcatac gtatcacaaa tggctagtga
    21241 ctacactgat ggtttagcac ttcaagccat taaattggtc tttgaaaatc tcgaaagctc
    21301 agttaagaat gcagacttcc actcacgtga gaaaatgcat aacgcttcaa caatcgctgg
    21361 tatggccttt gccaatgcct tcctaggtat ttctcactca atggcccata agattggtgc
    21421 gcaattccac acaatccacg gtcgtacaaa tgctatcttg cttccatacg ttatccgtta
    21481 caacggtaca cgtccagcta agacagcaac atggcctaag tacaactact accgtgcaga
    21541 tgaaaaatac caagatatcg cacgcatgct tggacttcca gcttctactc cagaagaagg
    21601 ggttgaatct tacgcaaaag ctgtctacga actcggtgaa cgtattggga tccaaatgaa
    21661 ttttagagac caaggaattg acgaaaaaga atggaaagaa cattctcgtg aattatcctt
    21721 cctggcttat gaagaccaat gttcaccagc taacccacgt cttccaatgg tagaccatat
    21781 gcaagaaatc atcgaagatg catactatgg ctacaaagaa agaccaggac gccgtaaata
    21841 attgtttatc agtctagaag caagacaaaa actcaatttg agggaaagat ccagtaattt
    21901 ttctatgata aaaggcatcc tatcaaggtt tttgaatacc tgataggatg cctttttatg
    21961 atgttgaggc ctttttgccc tttttgaaaa actagaatag aaacaaaata tatagcagat
    22021 tgaaactaga atagtacata tctgcttcta aaacattgtt agaattcgat ttgactgtcc
    22081 tgatcgattt gttctattct tatttcattt tactatacta tataaaaaat ata
//
LOCUS       DAVLCS010000034        19818 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLCS010000034 DAVLCS010000000
VERSION     DAVLCS010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19818
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.034"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(<1..992)
                     /locus_tag="VXC78_001524"
     CDS             complement(<1..992)
                     /locus_tag="VXC78_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583579.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEA"
     gene            complement(1002..1955)
                     /locus_tag="VXC78_001525"
     CDS             complement(1002..1955)
                     /locus_tag="VXC78_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0583580.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMSDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            complement(1948..3154)
                     /locus_tag="VXC78_001526"
                     /pseudo
     CDS             complement(1948..3154)
                     /locus_tag="VXC78_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            3397..3690
                     /locus_tag="VXC78_001527"
                     /pseudo
     CDS             3397..3690
                     /locus_tag="VXC78_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            3797..4148
                     /locus_tag="VXC78_001528"
                     /pseudo
     CDS             3797..4148
                     /locus_tag="VXC78_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4424..5730
                     /locus_tag="VXC78_001529"
                     /pseudo
     CDS             4424..5730
                     /locus_tag="VXC78_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5770..6780)
                     /gene="tsaD"
                     /locus_tag="VXC78_001530"
     CDS             complement(5770..6780)
                     /gene="tsaD"
                     /locus_tag="VXC78_001530"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV0583581.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(6770..7207)
                     /gene="rimI"
                     /locus_tag="VXC78_001531"
     CDS             complement(6770..7207)
                     /gene="rimI"
                     /locus_tag="VXC78_001531"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV0583582.1"
                     /translation="MIEIKRIQQQPDLAKAIYAVMIAVYPVSPWTLEQIQADLFQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGKGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIADRKAYYHDPVEDAIIMKREIDEG"
     gene            complement(7204..7887)
                     /gene="tsaB"
                     /locus_tag="VXC78_001532"
     CDS             complement(7204..7887)
                     /gene="tsaB"
                     /locus_tag="VXC78_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV0583583.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPR
                     QKEGLVVPIMDARRNNVYAGFYENAKPVLPEAHLSFAEVLEQVKDAEQVTFVGEVGAF
                     VEQIQEQLPQASYQETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8065..8250
                     /gene="cibA"
                     /locus_tag="VXC78_001533"
     CDS             8065..8250
                     /gene="cibA"
                     /locus_tag="VXC78_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV0583584.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8252..8404
                     /gene="cibB"
                     /locus_tag="VXC78_001534"
     CDS             8252..8404
                     /gene="cibB"
                     /locus_tag="VXC78_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV0583585.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            9222..9455
                     /locus_tag="VXC78_001535"
     CDS             9222..9455
                     /locus_tag="VXC78_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV0583586.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            9457..11136
                     /locus_tag="VXC78_001536"
     CDS             9457..11136
                     /locus_tag="VXC78_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0583587.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(11237..11326)
                     /locus_tag="VXC78_001537"
                     /pseudo
     CDS             complement(11237..11326)
                     /locus_tag="VXC78_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(11515..13428)
                     /gene="mnmG"
                     /locus_tag="VXC78_001538"
     CDS             complement(11515..13428)
                     /gene="mnmG"
                     /locus_tag="VXC78_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV0583588.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMILPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQDKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(13438..13893)
                     /locus_tag="VXC78_001539"
     CDS             complement(13438..13893)
                     /locus_tag="VXC78_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0583589.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNRKLLVTKDKGKYYIIGGA
                     IQVNEKTEDAVVREVKEELGVKSQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(14034..15155)
                     /gene="mnmA"
                     /locus_tag="VXC78_001540"
     CDS             complement(14034..15155)
                     /gene="mnmA"
                     /locus_tag="VXC78_001540"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV0583590.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            complement(15556..17649)
                     /gene="pspA"
                     /locus_tag="VXC78_001541"
     CDS             complement(15556..17649)
                     /gene="pspA"
                     /locus_tag="VXC78_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEV0583591.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKSEAAKKAYEEAKKKAEDAQKKYDEDQKKTEEKAENEKKAAADLNEATEVH
                     QKAYVRYFEIQRAKDSKKYKNNRDKYNKDLAEADQKIKDTKTVLDEKQSKFYAVRAVV
                     VPEAKELAVTKQKAEETKKGAEVAKEKYDKAAQEVEVAKKEVEAEEAELDKKVAELQN
                     KVADLEKEIADAEKTVADLEKEVAKLEKDVEGFKESDGEYAKFYLEAAEKDLATKKAK
                     LAEAKIKAATKKAELEPELEKAEAELENLLSTLDPEGKTQDELDKEAAEAELNKKVEA
                     LQNQVAELEEELSKLEDNLKDAETNNVEDYIKEGLEEAIATKQAELEKTQKELDAALN
                     ELGPDGDEEETPAPEAPAEQPKPEKPAEETPAPAPKPEKSADQQAEEDYARRSEEEYN
                     RLTQQQPPKAEKPAPAPAPKPEQPAPAPKTGWKQENGMWYFYNTDGSMATGWLQNNGS
                     WYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGWLQYN
                     DSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGWAK
                     VNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVN
                     TTVDGYKVNANGEWV"
     gene            complement(17935..18438)
                     /locus_tag="VXC78_001542"
     CDS             complement(17935..18438)
                     /locus_tag="VXC78_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583592.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDFASHTISVIQTGVFILEDFRNILLYNDVIERISLYEFIGDIFYSKLTSYC
                     IVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTN
                     VKEMKWL"
     gene            complement(19564..>19818)
                     /locus_tag="VXC78_001543"
     CDS             complement(19564..>19818)
                     /locus_tag="VXC78_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583593.1"
                     /translation="LIFLIKICADTTIKFLFIRLFDTSTLMKRRIFFLFALDVIVYLF
                     LGYLLVIQKAGYLFSVLLLFSNFSVPFIKEKEYELFKNSK"
BASE COUNT         5791 a         4347 c         3459 g         6221 t
ORIGIN      
        1 tttgcttcat ataacggaaa atctctattc acctcatttg gttcgatatc attcatttta
       61 tttgactcaa ttggattaat tgaatacaat tttaaaaaaa taggcttcgt accaataata
      121 gaggataatt gacctcctaa ttcacctagc gctgtaaaaa taacacctgt tagtgctcct
      181 attgcttcaa tagtaccaat tttcactatt ccttttattg caagatagcc tgttaaaaaa
      241 acgagagata tctgaaaaaa aatattgaga aagaagctaa tagcgcctgc taacgtttct
      301 acagttgtct ttctttgtat aaccatcttt aataaaattc ctgcttcttt aattttctta
      361 ggcaatacat ataaaagatt caaggatgct aacacatcaa atccattcaa tatagtctca
      421 ctagatttta aaaaagcttc attttggtta gttaaattta gactaacttc tcgcattttc
      481 gatgcaaaga tttttggtac aagtagcata atcattaatg aaaacaaggt ggctacagtc
      541 aatgaccaat gatagtgatt aagagtcaca actgcaaata tagtaccaga aattcctttt
      601 attactaaaa aaagttgttt aaaagcctga tcatttaaag tctgaacatc attatttagc
      661 cacgaaagat atgttcctga tgatttacta tgaaattctt gataggtaga gttagagatg
      721 tctgtggcaa ctctatttcg aatctctaga ttaaactctt ggatcacttc aacctgataa
      781 tttttcacta cccagtcaag gaatattatc ccacaccaga caatcatttg gtagattgac
      841 aatttcaaaa accgctctaa attcatcgca attaattcat tcaacaccag agcattaata
      901 gttgctgcat aaattagcaa taattgacca gcaacaataa atatcgttaa taaactaaat
      961 ttttttatat ttgattttat aatagtatac acaatagttt ctcactttct aaattttaat
     1021 tgaacatagt tgtcatatat acaatagaaa aaaccaaaat gatataataa catatatttc
     1081 aaaaaaagaa attcgttaaa aattttttct tctcttgcct tcttgattac ttttaaagcc
     1141 ttgcatttgt ctcctattaa tagtaaccgc tttatgttta aagaataata tttctttgta
     1201 accaatattc tctcgttgaa actcaataaa ttaaaatatt tcctacagta attataatat
     1261 tcttcatctg cattaattgt tttttgtgtc actccagtga taccgttttc tttactgtga
     1321 gcgtagtaat tcaccaagaa ttctcgcact atatcaattt ggtatccttg agcaagtagt
     1381 tttaataaaa caacaccgtc ctgatgtgaa tctattttct caaaaccatt aattaattct
     1441 agcacctctt ttttacacaa ccaaaatgac gtacctgcta tattgtgaac catttgaaca
     1501 aacaagggat ttccaacaaa atcggtcttc tcctcttctc gtgtaccatt tggataaatt
     1561 attattccat aactataaac taaagctaaa ttcttcattc tactcttttt aaaacaagcc
     1621 atcaacttta aaattcgatc tgacatatat tcatcatcat cgtctaaaaa tgatatatac
     1681 ttacctctag aatttttgat acctatgttt ctggcattag ttgcacctaa atcttcatta
     1741 cttaaaatta acttaattct atgattggta tagccaaatt gatggataat tttatttctt
     1801 aaatttacat tactataatt atcatcaata attataactt cgatattttt ataactttga
     1861 tgtaaacaac ttttcacagc tctaatcaga gattcatacc tattatgtgt tggtattata
     1921 atacttacta attcttgatc tatattccta tccatgacta ctcttctcta ataattcatc
     1981 atatactctc atggtttcta caaacatttt ttgcacagaa aaatgttttc ttatttttga
     2041 tttactattc tcacctatat atttcaaata ctcagaatca ttgagtaaaa aattagcaca
     2101 agcacacact ccctcaacat cttccttctc aaataaaaat ccatcaaccc tatgttcaat
     2161 aatttcactt aacccgccaa cattactagc taaaaccgga gttccttgtg acattgactc
     2221 taaaacacac ataggtattc cttctgtatc agaaggaata tacaataaat ccgatatttg
     2281 gtaaactata gtagctggat agatttcacc aagtaacctg aaattatctc tacatttcaa
     2341 atggcaaatt ttttctttca aagcagccca catactacca tttccagcca taataaaaat
     2401 cacatcttct ctgactaaaa ataatttttc tgcaaattca aggaatctat ccggcctttt
     2461 ttctggatcc aaccttccaa cataacaaat gatttttttg ttatttggaa tacaaaattc
     2521 ttttttaaag tcttgaacac ctactacatc taaatcgcta tttgatacat taattccgtt
     2581 atttattgca actatcttct tattttttta ttatactctc caatcttttt ttcatagttt
     2641 cagatacaca aataaaagca tctcccatag aatatgtcca aaaatcaaaa taagtcaaga
     2701 atttcttttt taagttatat tcaacccatc catggcatgt tatcactgtc ttaacctttc
     2761 caaatccatt cttgtcaagt ttttttaaca tatataaaaa ataattagtt gagtagccat
     2821 gacagtgtat aagttggatt tttaataatt ttaaaatatt tttaacgtgt aaggcagttt
     2881 caaaattatt tgaacattga gtacaatcaa cataggcaat atctaaattt ttataatcat
     2941 caataacctt tgaatctcta gatacgatta tcaaaatagg atatagagac atccttctga
     3001 tctgcttttt acaaagtcca attatatgcg gatctatacc tccacaatgt ccattattat
     3061 acctaactat aatatgagcc gaaaacacta tatccttaat gtctccatat ccatcaggga
     3121 tattaatatt tatttttcca caactatatt gcattgtaac catctcctta aacgacgcat
     3181 tatgatattt gatagagaaa tttttatgaa taactcaata attttatagt aaatcatgct
     3241 tatatctcaa agatacctat tttctcttgt ctcgaccttc tccaaagaat tgctataata
     3301 ctattacaaa tacatctgca ctacacttca aattttagca ctgtataaaa acgtttcaac
     3361 acactaactt taagaaaact tccactatta attgaaaaag ttgatagaga taaattaaag
     3421 atctatattg aaactcatcc cgatgcttat ttgactgaaa tagctgctga attcaactgt
     3481 cctccaacaa ctattcatta cgctctaaag gctatgggat atagtctaaa aaagagctgt
     3541 acctactgcg aacaagaccc agaaaaagta aatcggttcc ttaaagaatt gaatcactta
     3601 agctacctga ctcctattta tatttatgag acaggggttg agacctattt ttatctcgaa
     3661 tatgatcgag ccttgagcag gcagttagtc tctctggaag aagatataat tatttgaatt
     3721 aagatcgaga caacgcacac cagagattgc gatactgtta tagaagtact aatgcccttt
     3781 tttgtttcaa tatactatgg ctccgatgac ctataaagat acgatgacga gtgacttttt
     3841 cgaagcttgc ttccaaaaat tcttactacc tactttagat acaccatccc ttatcattat
     3901 ggacaatgca aggtttcaca gaatgaacat gtgtaaggag cagggcatag actgttacca
     3961 cttcctacct attcacccga gtataatccc attgagaaaa tatgggctta catcaaaaac
     4021 atctcagaat aatattgtca aattacgatg cttttcttga ggcacttttg tcctattctt
     4081 gtttcagccg actatactcc gttattgggc agctacggaa cagtcgatgg gacgatgggg
     4141 ggacataaaa aaatcctcca gttttgtttt ttataacagt atactggaga attgacaatc
     4201 tcggtagata cctcgttata gcgcggttac ttattaggca gttacaaaac aactgtgaac
     4261 agaaaacatt ccagagtcag acaagacttt ggaatgtttt ggctctataa tttctgtagt
     4321 gggtaatccc accccaggaa ttatagggtc gtttcttgta gaaaaaaagc cccatatgac
     4381 ctataatgaa aagcgtctaa ccaactcatt agaaagggtt catatggaac aacttaagaa
     4441 taccacagat ttgctcggat tgaaagacaa aaatatcaaa atcttgtctg ttctgaaata
     4501 ccaaacccat ctagtcgttc aggcaaagtt ggattccccc gctcctcctt gtcctcattg
     4561 tcaagggaag atgatcaaat acgacttcca gaaagcctct aaaattccgc ttctcgactg
     4621 tcagggttta cccacggtac tacatctcaa aaagcgccgc tttcagtgca agaattgcct
     4681 taaggtggtc gtttctcaaa catccattgt caagaaaaat tgccagattt ccaacatggt
     4741 gagacaaaaa atcgctcagc tcctccttga aaagcagtct atgactgaga ttgcccacag
     4801 attggcggtc tcaacttcca ccgtcatccg aaaactgagg gaatttaagt ttgaaaccga
     4861 ttggaccaag ttgccaaaag ttatgagttg ggatgagtat agcttcaaaa agagcaaaat
     4921 gagcttcatt gcccaagatt ttgagtccaa atccatcctc gcaattttag acgggcgaac
     4981 tcatgcggtg attcgaaacc atttccaacg ctatcagaga gaggttcggg agctggtcga
     5041 ggtcatcacc atggacatgt acagccctta ttatcggctc gctaagcaac tctttccaaa
     5101 ggcgaagatt gttcttgacc gcttccacat tgtccaacat ctgagccgag ctatgaaccg
     5161 agtacgaatc caaatcatga accaatttga ccgaaaatcc ttggagtatc gggcgctcaa
     5221 gcgcttttgg aaccctcgct ttttcgtttc taggctcggg ctaaatcagt ccactggact
     5281 gatttactac accaggatag cttcaagctc tgtcagaaac gattctatca gcccacgttt
     5341 cgaatgcact taacccatcg ggaagtacga gataagctgc tttcttactc tgagggatta
     5401 caggttcact acgaactcta tcaactcctg ctctttcatt ttcaagagaa gaatgccgac
     5461 catttctttg gattgattga gcaagaactg ccaacggttc atccgctttt tcaaacggtc
     5521 ttttggactt ttttaaggga tagagataag attatcaacg cacttaagct gccttattcc
     5581 aacgctaaac ttgaagcgac caataatttg attaaggtta tcaagcgcaa agcctttggt
     5641 ttccggaact ttaacaattt taaaaaacgg attttgatga ctttgaacat caaaaaagag
     5701 agtacgaatt tcgtactctc cagattgtag cttttcgcct acccactaca cttgacaaag
     5761 agccactctt tattccatgg tatcaaaggc aagacttggt ttggcattga ggtcccagcc
     5821 tgcgaagttt tctttgttcc actcgctgac gctggcatag gcaatcatac ctgcattgtc
     5881 tccgcagagt cgcagagggg ggatgataac cttgacatct gtgatttcgg ctgctaggcg
     5941 ttctctgaga cctttattgg ctgccacacc acctgccaca actagggttt taacaggata
     6001 tttctccaaa gccttcttgg tttttgccat gagaatgtcc ataactgctg cttggaagga
     6061 agcacacaaa tcttctgtag acaggctttc tcccttttgc tcggcattgt gatgaagatt
     6121 gataaaggca gatttcaaac ctgagaagga gaactccaga ttatcttcct taatcatggc
     6181 acgggggaaa tcataaatat cctgcccctg atgagccagc tcgtcaatct cacgacctgc
     6241 aggataggtc aagcccatga cacgaccgac cttgtcataa gcctccccaa ctgcatcgtc
     6301 tcgtgtctcc ccaacaatct tgtaatctcc tgcctccgaa acatagacca actctgtgtg
     6361 cccaccgcta accaagaggg ctagcaaggg aaactccaaa ggctccacac tctgagctgc
     6421 catgaggtgc ccagccatgt gattaacagg aatcagtgga agtccgtgag cccaagcaaa
     6481 ggccttggca gctgacaaac caactagcaa ggctccgacc aagcctggtc cgtaggtaac
     6541 cgcaacagct gtcacatcct cttcggtaat ccctgcttct gccaatgcct cctcgataca
     6601 ggctgtaatg acctcgacat ggtgacgact ggctacttcg ggcactacgc caccaaaacg
     6661 tttgtgactc tcaatttgac tagcaatgac attggacaag agctcatcgt cgtttttcaa
     6721 gacggcgaca ctggtctcat cacaggatgt ctcaaatgct aaaatatatc tatccttcat
     6781 ctatttctct cttcatgata atggcgtcct cgactgggtc atggtagtag gcctttcgat
     6841 cagcgatgac cgccattttt tctttcttgt aaaatgcttg cgctcgttga tttgactttc
     6901 tgacttcgag gaaaatctcc ttatctgtcg gcaattgagc aaacaaggct gacgcaatgc
     6961 ccttaccctg ataggctcct ttgacagcga tttgcaggac ttctgcttca aagagagtct
     7021 cctgaacagc tagaaagcca atcacttctg ccccatcata agccagagca taccaagtct
     7081 ggtcttggaa caggtcagct tggatttgtt ccagcgtcca aggactgact gggtaaacag
     7141 ctatcataac agcgtagatg gctttagcta gatcaggctg ctgttggatt cgtttgattt
     7201 ctatcatagg cgtttaatgt aagactcgcc agactcggta tggttcttga gccagttttc
     7261 ctcagcctcg acacgcttga ggtaatttgg cacaaagtcg tgcaaggagt ctgcttcttt
     7321 gtcccaagcc caaagagcta gattagctgc atttggcaag gtttcttggt agctggcttg
     7381 tggtagttgt tcttggatct gttccacaaa ggctccaact tctccgacaa aggtcacctg
     7441 ctcagcatcc ttgacctgct ctagcacttc cgcaaaagac agatgcgctt ctggcaagac
     7501 tggcttggca ttttcataaa agcctgcata gacattgttg cgacgcgcat ccatgatagg
     7561 aaccaccaag ccttcttttt ggcgtggcac cagagccaat agactagaca tcccaactaa
     7621 ctcaatgttc agggtatgag ccaaggtctt ggcagttgct accgcaattc gcaagcctgt
     7681 atagctaccc ggcccttcag ctaccacgat tcggtccaaa tccttgggtg tccaatccaa
     7741 acttgccatc aaaaaatcta tggcaggcat aagagtaata ctgtgatttt tcttaatatt
     7801 aatcgtcgtc tcggcaagaa cctgcttgtc ctctaaaata gcgagagaaa gagccttgct
     7861 ggacgtatca aaagctaata ctttcataac acattcctat ctttttgtct gcttactatt
     7921 atactacaaa agctggcaca tgggaatttt ctttgccccc agacaagagt gccctcactt
     7981 aactaaaaat aatttaaaaa aatgctcact tttccttttc ttttccgaat ataaaagtga
     8041 acaagaaaaa aggaggaaag ttcaatgaca aattttgaca ttcttgacaa tcaattttta
     8101 tccttatctg aaaatgaatt atcagatatt gatggcggtc tcgctccctt ggttatcttt
     8161 ggagtagcag tatcttggaa ggctattgca ggtggaacag cacttatagg ttctggtttg
     8221 gcagctggtt attttttagg aggagattaa tatgatgaaa aatttgaaca actatcgtga
     8281 aatttctaat aaggaattgc aagaaatcaa gggtggcttt ggtgtaggtg ttggtatcgc
     8341 tttatttatg gcaggttata ccattggaaa agaccttcgt aaaaagtttg gtaagtcatg
     8401 ctagataaga aacacatttt tagaaggata aattttattg tcttcatctc ttacagtttg
     8461 ctcagcattc tcaatgattt gaacattact actatccctt taccattcga tttatctgtt
     8521 tgtattgttt tatttttatg cttcaactct atttttgagc agaacaatga ctcccataaa
     8581 aataataagc tttgaaaatt ccattgtcat gtcattttag aaaaatgcaa agaccacctc
     8641 atcttgatag atggggtgga attttcgtgt cgtaaatcta ctatctctac atccccaaac
     8701 aaaaaacccc agcataagca gggcatctaa gcatttaatc caaagtaaaa tacaaaccaa
     8761 acgacatagg gcacgaggag gagaaaaagc gagtagagag tcacaaaggt aattttccac
     8821 aagaacttgg tttgtcatcg ttccagtttg gcaaatggaa gatttcctcc ataaacgcaa
     8881 gcaacaaaaa cgataaaagc taacaaacga actccgatag caaaagcaaa taagttatac
     8941 atagggcaac ctccttgact taaaatctat atggaattat gacaagcaat aaatttcact
     9001 tccgttatca acataataca ttttctttat ttttgtaaac gcttaccaaa gaaattgccc
     9061 cctaactttc tcgtttccgt cttttactaa tttttcattt tgtggtataa ttgaaataat
     9121 tgtaacgaat caaggtcaat ctagacacaa aatggaatga aatcaagcaa atatctgcta
     9181 aaagtttgga ataagctgac ctgtaaatag aaaggaacta tatgatttac aaagtttttt
     9241 atcaagaaac aaaagaacgt agcccacgcc gtgaaacaac acgcgcgctt tacctagaca
     9301 tcgatgccag ctcagaactt gagggccgta tcactgctcg ccaacttgtc gaagaaaatc
     9361 gcccagagta caatatcgaa tatatcgaac tcttgtctga caaattgctc gattacgaaa
     9421 aagaaactgg cgccttcgaa attacggagt tctaatatgg cctacactct taaacctgaa
     9481 gaagtcggcg tttttgccat cggtggtcta ggagaaatcg ggaaaaacac ttacggaatt
     9541 gaataccaag acgagattat catcgtcgat gctgggatta aattcccaga agatgacttg
     9601 cttggtatcg actatgtcat tcctgactac tcttacatcg tggacaatat cgaccgcgtc
     9661 aaggctgttt taatcacaca cggacacgag gaccacattg gtgggattcc gttcctactc
     9721 aagcaagcaa atgtccctat ctacgctgga ccgcttgcct tggctttgat ccgtgggaaa
     9781 ctcgaagaac acggcctctt gcgcaacgcc aaactttacg aaatcaacca caacaccgag
     9841 ttgaccttta aaaatctcaa ggcaactttc tttagaacga ctcactctat tccagagcct
     9901 ttggggattg tcattcatac tcctcaaggg aaaatcgtct gtacggggga ctttaagttc
     9961 gactttactc cagttggaga acctgcggac ttgcatcgta tggctgcgct tggtgaagaa
    10021 ggtgtgctct gtctcctgtc tgactcgaca aatgcggaag taccaacctt taccaactct
    10081 gaaaaagtcg ttggtcagtc cattatgaag attatccaag gtattgaagg acgtatcatc
    10141 tttgcatcct ttgcctcaaa tatcttccgt ctccagcagg caacagaagc tgctgttaag
    10201 actggacgca agattgcggt ctttggtcgt tctatggaaa aggccattgt caacggaatc
    10261 gatcttggct acatcaaagc tcctaaggga acctttatcg agccaaatga aatcaaagat
    10321 tatcctgcag gagaagttct tatcctctgt acaggtagtc agggtgagcc tatggcagcc
    10381 ctctctcgta tcgccaacgg aacccaccgt caagtacaat tacaaccagg tgataccgtt
    10441 atcttctctt ctagtcccat ccctggaaac actactagcg tcaacaagct gattaacatc
    10501 atttctgaag ctggtgtcga agttatccac ggtaaagtga acaatatcca tacatctgga
    10561 cacggtggtc agcaagagca aaaactcatg ctctgcttga ttaagccaaa atacttcatg
    10621 cctgtccacg gtgaataccg catgcaaaaa gtccacgctg gactagcagt ggatactggt
    10681 gttgagaagg acaatatctt tatcatgagc aatggcgatg tgcttgccct tactgctgac
    10741 tcagctcgta tcgcaggtca tttcaacgcc caagatatct atgtcgatgg aaatcgtatc
    10801 ggtgaaattg gcgcagctgt cctcaaagat cgtcgcgatc tatctgaaga cggtgtcgtt
    10861 ctggcagtcg caactgttga cttcaaatcg cagatgattc tatctggtcc agacatcctc
    10921 agccgaggct ttgtctacat gagagagtct ggcgacttga ttcgccaaag ccagcgtatc
    10981 ctcttcaatg ccattcgtat cgcactgaaa aataaggatg ctagcgtgca atctgtcaat
    11041 ggtgccattg tcaacgctat tcgccccttc ctctatgaaa ataccgaacg tgaaccgatc
    11101 atcatcccga tgatcctcac accagatgaa gaataatact cttcaaacca cgtcagcttc
    11161 gccttgccgt atatatgtta ctgacttcgt cagttctatc cacaacctca aaacggtgtt
    11221 ttgagctgac ttcgtcagtt ctatctacaa cctcaaagca gtgctttgag caacctacgg
    11281 ctagcttcct agtttgctct ttgattttca ttgagtacaa gtcaacaaaa cagccccgtc
    11341 ttcggagctg tttttctcta tgctttcttt tgagattaaa actcaatgaa aatcagacca
    11401 gaaggctagg aaaatgcata acttgagtta gctcccatag ttcgggaaac tatgggaggc
    11461 tggagatgaa tcaaagccaa gctttgaact cattcgtaag aagccgacga cgtatcattt
    11521 tgatttttga agagttttag aaatactacg atttttacct tccagataca ccatcaaaat
    11581 agaaatatct gctgggttta cccccgaaat acggctggct tggccgatgg tttctggatt
    11641 gatgagtttg aacttctgac gagcttccgt cgcaatagaa tcgatgtcat cccagtcaat
    11701 attggctgga atgcgttttt cttccatacg tttcatcttg gcaacctgat ccatggcttt
    11761 tgaaatatag ccttcgtact tgatttctgt ttcaatcaat tcgataatct tatcatccaa
    11821 atcctctgca gctggtccga tgaaggctac cacatcttgg taagaaactt ctggacggcg
    11881 aaggaattcc ttggctgtca ctgcatctgt caagggtttg aagcccatct cctcaacctt
    11941 agcattggtt tccttgactg gcttgagttt gatactgtct aggcgtttca tctcattatc
    12001 aaattgattt ttcttgattt caaaacgagc ccagcgttca tcatccacaa ggccaatctc
    12061 gcgtcccatc tcagtcaagc gcatatcagc attgtcatga cggagaatga gacggtattc
    12121 agcacgactg gtcaagagac ggtagggttc gatggttccc ttggtcacca aatcatcaat
    12181 catgacccca atgtaaccgt cactacgctt caaaatcaac tcaggcttat cttggatttt
    12241 cagagccgca ttgatccctg cgataatccc ttggcctgct gcctcttcgt aacctgatgt
    12301 tccatttgtc tgaccagcag tgaaaagtcc tgagattttc ttggtttcca aagtcgcacg
    12361 caactggtga ggcaagatca tgtcatactc aatagcataa cctgttcgca tcatctctgc
    12421 attttccaga cctttgatgg aatgaaccaa gtcacgttgg acatcctcag gcagactggt
    12481 tgaaagtcct tggacataga cctcctctgt attgcgtcct tctggctcaa ggaagagttg
    12541 gtgacgttcc ttgtccgcaa agcgcacaat cttgtcctca atcgatggac agtaacgagg
    12601 tcccactccc ttgaccacac ctgtaaacat aggcgcacgg tggaggttgt tttggataat
    12661 ctcatgactg gtaccattgg tgtaggtcaa ccagcatggc acttggtcct tgacataatc
    12721 ctcatcacgt gaagtgtatg agaagtgatt aggtgcttca tctcctggtt ggatttctgt
    12781 cacatcgtaa ttgatagaag aagccttgac acgtggaggg gttcctgtct tgaaacgacc
    12841 gatttcgagg cccagttcct tgagattgtc agctaggtta atagaagcca agctgtggtt
    12901 aggacctgat gagtacttga ggtctccgat gataatttcc ccacggagag cagtccctgt
    12961 cgtcacaata acagccttag cagcatattc ttgatgggtg gctgtacgca caccgacaac
    13021 cttgccatct tccaccaaaa tctcatcaat catggtttga cgaagggtca gattttcttg
    13081 gttttcaacc gtcttgcgca tctccttaga gtaaagttcc ttgtcagcct gcgcacgaag
    13141 ggcacggaca gctggcccct tccctgtgtt tagcatcttc atctggatgt aagtcttgtc
    13201 aatggttttg gccatctcgc caccgagggc atcgacttca cgcacgacaa tccccttggc
    13261 agaaccaccg atagagggat tacaaggcat gaaagccagc atttcaatat tgatggtcgc
    13321 aagcaggacc ttacagccca tacggctagc ggccaaggaa gcctcaaccc cagcgtgtcc
    13381 cgcaccaatt acaataatat cgtattcttc agtaaaatga taagtcatgt ttctctccta
    13441 ttcctcaaga tgaatgtgtc ttagttggcc ttcccaatct ggtagggccg tttttaaaaa
    13501 ggctggaact agctggatat cctcaagctt atccaagtca atccactcac agggctgcct
    13561 tttctcatct tcctgcatgg tcaacggggc atcttcaagc aaatccacca gataatgaaa
    13621 ctcgatattg tgataggaaa cgccgtccac ttcaaaacga ttttcaacca caaaagctag
    13681 ctgcccagct tgagatttaa cacccagttc ttccttcact tcacggacta ccgcgtcttc
    13741 cgttttttcg ttaacttgaa tcgcaccgcc gataatgtaa tacttgccct tgtctttggt
    13801 gactagaagc ttgcgatttt gaagaatcaa agctgtcgcc cgaacaccaa aaaccgtatt
    13861 gtctactttt gtccgaaagt cttgttgagt cattcttgtc ctttccctta aacgacacaa
    13921 aaacagtcaa aactacaaag aagtgcagga caaaaaagcc tgcaacatcc atgagctttg
    13981 accatcattt ctattgctgt tattattgta gcaaattgag aaaatttgtc aatctaaatg
    14041 tactgacaaa cttgtccatc gcggtaagca ttgtcaatca aaccgccacc tagacactct
    14101 tcgccatcgt aaaagacaac tgcctgtcct ggtgtaatcg cgcgttgtgg ttccgcaaag
    14161 ataacttctg ccttgtctcc tttgacatgg acggtcacct tagagtcagg ctgacggtaa
    14221 cggaatttag ccgtacattc tagcgtaaac tcttctggca tttcacgagt aaagtggact
    14281 tgactggctt ctaggctagt tgacatgagc gaatcatggt agaatccttg tcctacatag
    14341 agaatattct tgcttagatc ttttccgaca acgaaccaag gggcattgtc accgccgtgt
    14401 tgcccaccga taccgagtcc gccacgctga ccgattgtat agtacataag acctgcatgc
    14461 tcgcccatat cgcgaccatc cacagtcatc atgcgaccag gctgagctgg caggtagttg
    14521 ctgagaaagt ttttaaagtt cttttctccg ataaagcaaa tccctgtcga gtctttcttc
    14581 ttagcagtcg aaaggcctgc ttcttctgct agtctgcgta cttcaggctt ttccaaatgt
    14641 cccagaggga acatggtttt ttggagttgt tcttgcgaaa gttggctgag gaaataggtc
    14701 tggtccttgc cattgtccac gccacgaagc atgtgaacag tgccatcctc atcacgcgcc
    14761 actcgagcat agtgcccagt cgctacatag tctgccccca aggtcatggc atagtccaaa
    14821 aaggccttga acttgatttc cttgttgcac ataacgtccg gatttggcgt gcgccctgca
    14881 cggtattccg ctaggaaata ctcaaaaacg cggtcccagt actctttttc aaaattgaca
    14941 gagtagtagg gaatgccaat ctggtctgcc accgcaacca catccttgta atcttcggtc
    15001 gccgtacaga cgccgttttc atctgtgtca tcccagttct tcatgaagat accgatcaca
    15061 tcgtagccct gctccttgag caaaagagcc gtcaccgacg aatcaacacc accactcatc
    15121 cccacgacaa cacgtgtttt agagttatca ctcatggtaa gtctcccatc tattcgttta
    15181 ttcacgattg aaggtcgtgt gtgcttcacg attgaaggtc gcttgagcag tattcattat
    15241 aacacgcttg gttagagaag acaaggaaga gcttaaaaat tgttttttaa aacttatagt
    15301 caatatacag attatgtgaa tgatgtgagt ataccttctt cttatcttca ttcaaataac
    15361 tataataaat aaaacaaccc attttctcta atctattttt caagttagag aaaaggagtc
    15421 gtttttttaa tgacatttcc tgaaatcata agataggtac ctaaagaata cgaacataaa
    15481 tctattcaat cgaaccttat ctttgtttca aaattaaaat gtcaaatgtt cttaacatga
    15541 tttaatttaa tcggcttaaa cccattcacc attggcattg actttatagc catctacagt
    15601 tgtgttgact gcaagggcac ctaaaccatt gacatagtac catttatctg atactttgaa
    15661 ccattggctt gctttcatag cacctgatgc ttcaagatag taccaggtat ctccatcttt
    15721 cacccaacct gttgccattg aaccgttagc gttgaggtag taccatgaac cgttgacttt
    15781 agcccaacct gttgccatag caccgttagc gtttaggtag taccatgaac cgttgacttt
    15841 agcccaacct gttgccatag caccattagc gtttaggtag taccatgaac cattgacttt
    15901 agcccaacct gttgccatag cgccgttagc gtttaggtaa taccatgaat cgttgtattg
    15961 gagccatcct gtagccatag caccattagc gtttaggtag taccatgaac cgttgacttt
    16021 agcccaacct gttgccatag cgccgttagc gtttaggtaa taccatgaac cattgtattg
    16081 gagccatcct gtagccatag caccattgct gttgaggtag taccatgaac cgttgttttg
    16141 tagccaacct gtagccattg aaccatcagt attgtagaag taccacatac cgttttcttg
    16201 tttccagccc gtttttggtg cgggagctgg ttgctctggt tttggtgcag gagctggagc
    16261 tggtttttct gcttttggcg gttgctgttg agtcaagcgg ttatattctt cttctgatct
    16321 acgagcatag tcttcttcag cttgttgatc tgctgacttc tctggttttg gtgcaggagc
    16381 tggagtttct tcagctggtt tttctggttt tggttgttca gctggtgctt ctggggctgg
    16441 agtttcttct tcatctccat cagggcctaa ctcattaaga gctgcatcta actctttttg
    16501 agttttttct aactcagctt gtttagtcgc gatagcttct tctaaacctt ctttaatgta
    16561 gtcttcaacg ttgtttgttt cagcatcttt aagattatct tcaagttttg aaagttcttc
    16621 ttctaattca gcaacttggt tttgaagagc ttcaactttt ttattcaact cagcttcagc
    16681 agcttcttta tctaattcat cctgagtctt accttcaggg tctagtgtag ataataggtt
    16741 ttcaagttca gcttctgctt tttctaattc aggttctaat tcagcttttt tagtagcagc
    16801 tttaatttta gcttctgcta atttagcttt tttagtagct aggtcttttt cagcagcttc
    16861 aaggtagaat ttggcatatt caccatctga ttctttgaaa ccttctacat ctttttcaag
    16921 tttagcaact tctttttcta aatctgctac cgttttttca gcatcagcta tttctttttc
    16981 taaatcagca actttatttt gaagttcagc aactttttta tccaactcag cttcttctgc
    17041 ctctacttct ttcttcgcta cttctacctc ttgagctgcc ttatcatatt tctccttagc
    17101 tacttcggcg ccttttttag tttcttccgc tttttgttta gtaacagcta actcctttgc
    17161 ttcaggaact acaactgctc ttacagcata aaatttagat tgcttttcat ctaatactgt
    17221 ttttgtatcc tttatttttt gatctgcttc agcgagatct ttattgtact tatcacgatt
    17281 atttttatat ttttttgaat cttttgctcg ttgaatttca aaatacctta catatgcttt
    17341 ttgatgcact tctgtggctt cgttcaagtc tgctgctgcc tttttttcat tttcggcttt
    17401 ctcttcagtt ttcttctgat cctcatcata ttttttctga gcgtcttctg ctttcttttt
    17461 agcttcttcg taagccttct tagcagcttc agattttttc actgctgcat catagtcttt
    17521 ctcagcttta gactgactag ctacgggggc ttcttctgct cttacaaaag taggctgaga
    17581 cgtaacaaaa ccagccccta agatagcgac gctggctaga cttgttaaaa tcattttttt
    17641 cttattcatc taaatttacc tcttttctga tagtcatttt tagactatac ttatattaag
    17701 tatactcccc ccgtaaatat ttgtcaaatg ttttatatta catttttatt acaaatttct
    17761 atatcataag cttctactcc aaaaagataa agacactact tttgcccttt tcgattctct
    17821 ttttaaacat agcatcatct tccttcattc ctataaaaac atttccgatg agagagcttg
    17881 ttttttaatt tcgttaaaca acaaaaaacg caagcttaag gctgcggaca atctttatag
    17941 ccatttcatt tctttcacat ttgttttacg aactttagca tatttcttag cgcttgtaaa
    18001 atgtagagta actggtttaa atactccgct tttatctctt cgtaaaccta aaactgcgga
    18061 tcttttattt ttatcctcaa aaaatatgac gtccaatttc atagtatttt tagataaatc
    18121 cttagctacg atgcaataac ttgttagctt agaatagaag atatcgccga taaactcata
    18181 taaagatatc ctttcgatta catcattgta caataggata tttctaaaat cttccaaaat
    18241 aaaaacacca gtttgaataa cagatatcgt atgactagca aaatctcgtg tgattttgtg
    18301 taagccaaat aaatgatgta aatcagtcaa gcaaaaattc actttgaaag tctctaaata
    18361 cttataattc gttgatactt gacatgtttt tccattgaat ctttcttgat aatccaaaat
    18421 acaatcaagt aatttcaacg acaaactcca tattttctca aaataaaaag cacggggcag
    18481 ttctcactac tgcccaaagt gattgattag agtcggcttc tctaactccc tatgttgtgc
    18541 ttattaggct tatcgcaagg gaacagtttt tagctctgcc aagccacata gtgtgcttac
    18601 tactatgtgt ccatgtcacc atgaattgcc gaacggttta acgagaaagt atagtagatt
    18661 gaaacaagat gtgaacaaat cgattaggaa agtcaaatta atttctagaa atattttaac
    18721 agtcataacg gactattcca gattcaatct actatattac ttttaggttt atcccaactc
    18781 aattatgaca tttttttcaa aagtcaatat atctcactct tttcaacgac aagaaagagg
    18841 ctgataatcg accaacctct gtttttagat acagttcaag tccaaactat tctttataga
    18901 aaagtccgat aaattcgagc aatagttaac atacttacaa atataactcc caaaatagat
    18961 aacactattt tcacaaaact cagttccgaa cctatgacat atatatgaaa aagaggggct
    19021 agtcctacac atatatacaa taagtagcca acaagtttta tctcaccaat tcctgcaaaa
    19081 aaatgtttca tgtgacgatt ctccatttac tccataaatc agttttattt tagactatca
    19141 taaaacaatc acctcttcaa taaaaaccat ttgcgaaata ctattctgaa gcattgatag
    19201 gtcagatttc tcagaataga gctgtcctaa ctatcgagca gctcaaatac atatatatga
    19261 gcaattctaa tcttagaatt gctataaaat aaatgttttc gggctattct aagtctttga
    19321 ctgcttaaaa ttttacgttc tgaaggattc taaagctaga atagctcaaa atcacgagaa
    19381 ctaaggtatt caaaacttca gagtaataca atccccatag gaattctcca ttcttattaa
    19441 gcatgattaa aatgtaatcc taacaagtga tcctcgactg tgtttatagt acttggttac
    19501 ctagatagct ttcctttatc atgtctgatt ttaagccgtt ctaagattta atccatattt
    19561 ctattacttg ctatttttaa ataattcgta ttccttttct ttgataaatg gaactgaaaa
    19621 attagaaaaa agaagtaaaa ccgaaaacaa atagcctgct ttttgaatca ctaaaagata
    19681 tcctaaaaat aagtaaacta taacatccaa tgcgaaaaga aaaaatattc tcctcttcat
    19741 taaagtactt gtgtcaaata atctgatgaa taaaaatttt atcgtagtat ctgcacaaat
    19801 ttttatcaaa aagataag
//
LOCUS       DAVLCS010000035        19241 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLCS010000035 DAVLCS010000000
VERSION     DAVLCS010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19241
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.035"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            76..1005
                     /locus_tag="VXC78_001544"
     CDS             76..1005
                     /locus_tag="VXC78_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001150386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0583594.1"
                     /translation="MQDESIYGLVYKTIREERGFTQKEAAGTTVTPHFLRQFEQGKSR
                     ITIQKFEEILSNIGIDKETFDSLKTQMFPTEFHKLQAQVADLAYKREFKKIISLINQP
                     MENPGIAEHYVIANRVVNKFAIANIIGDSFLTPKDYQELEYIKNYLSELDDWNKIEVN
                     IFSSILPHFSIEFLDYRLYHLLDTLKKQTEYHSIRTADYYIACLRTAIKHYSVNGYYD
                     KAESLAVKTLEVINTFPLLSTKMTEMISLSMERANNFLRKDDVRGLELAKHIFASLDN
                     FEKVYPNQLLTRMREDFFVTVTQLNHTGQPLDV"
     gene            complement(1055..3391)
                     /locus_tag="VXC78_001545"
     CDS             complement(1055..3391)
                     /locus_tag="VXC78_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV0583595.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLGPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGAALNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESRVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQVDQD
                     NDVNRIIEQLEEQTLESHKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKILQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQVQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDAFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(3495..4043)
                     /locus_tag="VXC78_001546"
     CDS             complement(3495..4043)
                     /locus_tag="VXC78_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV0583596.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(4040..4342)
                     /gene="zapA"
                     /locus_tag="VXC78_001547"
     CDS             complement(4040..4342)
                     /gene="zapA"
                     /locus_tag="VXC78_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV0583597.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            4429..5310
                     /locus_tag="VXC78_001548"
     CDS             4429..5310
                     /locus_tag="VXC78_001548"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV0583598.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVITRDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            5314..5928
                     /gene="lepB"
                     /locus_tag="VXC78_001549"
     CDS             5314..5928
                     /gene="lepB"
                     /locus_tag="VXC78_001549"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV0583599.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            6056..8422
                     /locus_tag="VXC78_001550"
     CDS             6056..8422
                     /locus_tag="VXC78_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV0583600.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(8470..9753)
                     /locus_tag="VXC78_001551"
     CDS             complement(8470..9753)
                     /locus_tag="VXC78_001551"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV0583601.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(9947..10306)
                     /locus_tag="VXC78_001552"
     CDS             complement(9947..10306)
                     /locus_tag="VXC78_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0583602.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPIIAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(10605..11234)
                     /locus_tag="VXC78_001553"
     CDS             complement(10605..11234)
                     /locus_tag="VXC78_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0583603.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPAVSPSQELFGKIKVKEVCYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGFPTSQKNLTGITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLSFIYSVLKGYSLEGW"
     gene            complement(11279..11518)
                     /locus_tag="VXC78_001554"
     CDS             complement(11279..11518)
                     /locus_tag="VXC78_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583604.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(11668..11934)
                     /locus_tag="VXC78_001555"
                     /pseudo
     CDS             complement(11668..11934)
                     /locus_tag="VXC78_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(11959..12270)
                     /locus_tag="VXC78_001556"
     CDS             complement(11959..12270)
                     /locus_tag="VXC78_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002876249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0583605.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKTMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(12195..12437)
                     /locus_tag="VXC78_001557"
                     /pseudo
     CDS             complement(12195..12437)
                     /locus_tag="VXC78_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(12438..13070)
                     /locus_tag="VXC78_001558"
     CDS             complement(12438..13070)
                     /locus_tag="VXC78_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0583606.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF"
     gene            complement(13084..14079)
                     /locus_tag="VXC78_001559"
     CDS             complement(13084..14079)
                     /locus_tag="VXC78_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0583607.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(14076..14774)
                     /locus_tag="VXC78_001560"
     CDS             complement(14076..14774)
                     /locus_tag="VXC78_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV0583608.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(14851..15861)
                     /locus_tag="VXC78_001561"
     CDS             complement(14851..15861)
                     /locus_tag="VXC78_001561"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV0583609.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(15845..16852)
                     /locus_tag="VXC78_001562"
     CDS             complement(15845..16852)
                     /locus_tag="VXC78_001562"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV0583610.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRSFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(16839..17792)
                     /gene="mvaD"
                     /locus_tag="VXC78_001563"
     CDS             complement(16839..17792)
                     /gene="mvaD"
                     /locus_tag="VXC78_001563"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV0583611.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(17774..18652)
                     /gene="mvk"
                     /locus_tag="VXC78_001564"
     CDS             complement(17774..18652)
                     /gene="mvk"
                     /locus_tag="VXC78_001564"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV0583612.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(18774..19103)
                     /locus_tag="VXC78_001565"
     CDS             complement(18774..19103)
                     /locus_tag="VXC78_001565"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0583613.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TSCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
BASE COUNT         5581 a         4353 c         3631 g         5676 t
ORIGIN      
        1 acttttttct aaaaattccc ttaaaaactg gtagaattat gatagaatag aaaaaaggat
       61 tcgaggagat ttaggatgca agatgaaagt atttatggat tagtctataa gaccatccgt
      121 gaggaaagag ggtttacaca gaaggaagct gctgggacta cagtgactcc tcatttttta
      181 cgtcagtttg agcaagggaa atctcgaata accattcaaa aatttgaaga gattctttct
      241 aatattggaa ttgataaaga gacctttgat agtctcaaaa cacagatgtt tccaacggaa
      301 tttcataaat tacaggctca agttgctgat ttggcctata agcgtgaatt taaaaagatc
      361 attagtttga ttaatcaacc catggaaaat cctgggatcg ctgaacacta tgtgattgcc
      421 aatcgtgtag tcaataaatt tgctatcgca aacatcatcg gcgattcttt tctgactcca
      481 aaagattacc aagaactaga atatatcaaa aactatctga gtgaattaga cgactggaac
      541 aaaattgagg tcaatatctt ttcatctatc ctgcctcact tttcaatcga atttttagat
      601 tataggctct accacttatt agatactcta aaaaaacaga ctgaatacca ttcaatccgt
      661 actgctgact actatattgc ctgcttaaga actgctatca agcattactc tgttaatggc
      721 tactatgata aagctgagag cttagctgtg aaaaccttgg aagtgattaa tactttccct
      781 ctactgagca ccaagatgac agagatgatt agtctttcca tggaacgggc taataatttt
      841 ctcagaaaag atgatgtcag aggtctagag cttgctaaac atatctttgc cagtcttgat
      901 aactttgaaa aggtctatcc aaatcaactt ctgactcgaa tgagagagga tttctttgtt
      961 actgtcacac aactcaatca cactggacaa cctttagatg tctaacctag aaaataaaaa
     1021 agcttgagga accacatatt tcctcaggct tttcttatcc tttaaaagtg acaatagtcg
     1081 cgccactgcc tccagcattt tgtggggcat agccaaaact cttgacatgt ttgtttcttt
     1141 gtaggtattt ggtgactcct tcacggatga cacctgttcc gataccatga atgatatcaa
     1201 cttgagccat attgttaagc agggcttggt cgataaaggc atctagctca ttcatggcct
     1261 cttcatagcg tttgcctcga aggtccagtc tggcttgtgg acctcggcca gatgtccgtt
     1321 taacaacatt gacttgtttc ttcttaactg gcttttcttg ctgaacttga acaaggtcaa
     1381 actctttctc ttccagggtc atcttaatca agccaacttg ggcttcccag cggccgtcct
     1441 tgagttgact ggtcagggta ccacgctggc cataactgag aaccacgata tcatctccca
     1501 cctttggagc tcgttttttc ttggcctttt gaaggatctt gtttttagac aaatctactt
     1561 tttcaggagc caattttttc agcttggcct tggcttcaat gatttcgtgg ggcttgagtt
     1621 gagatttact gtggagattt ttgagaatct ggtcactctc actgagggcc atgtccacaa
     1681 tctcagcagc ctgttcacgc gccttattaa gctcggtttc cttttcacga ttgagttcgt
     1741 tgtaaagttt tttgagagca cggttcatct tgagattttc ttgctccacc tcacggatat
     1801 tgtccaagcg tttatgactt tcaagcgtct gctcttccaa ttgttcaata atccgattga
     1861 catcattgtc ctgatcgacc tgctggctgg catcccctac gataacttca gataggccta
     1921 gacgtttggc aatttcaaag gcattacttc ggccaggaac accctgcata aagcgataag
     1981 tcgggcgaag agttgcagta tcaaactcca tactagcatt ttgcacaaag gctgtctcaa
     2041 taccgtaagc ctttagttcc ggatagtggg tagtcgccat ggtcttgatt tgacgcaggc
     2101 gaaggtcctc cagaatagcc atggcaagag cagctccttc ttgagggtct gtaccagccc
     2161 ccaactcatc caagagtaag agtgaatgtt gattgacctt gccaagaata tccacgatat
     2221 tggtcatgtg gctagagaag gtagacaagc tctgctcaat agactgctca tctccaatat
     2281 cggcaaagat ttcttcaaag ataccaacac gactgccctt atctgctaaa atcggcaaac
     2341 cggactgagc catgacctgt gtcaagccga gagttttaag catgatggtc ttaccacctg
     2401 tattgggacc tgtaatgaca atagctgtta aatcttgacc aaaatggaca tcatttgcga
     2461 cagcattttt gaccaaagga tggcagacat ggagcagttg aatctcttga ttttctgaca
     2521 gctgaggtac gactgcttgc ctttcttgga taaagcggac cttggcacga atcaagtcta
     2581 gatgaccgat aatccaggcg tcattggcaa tctcagccgc atgagggcgg acacgctcag
     2641 aaatttcttg gagaatgcga agcatttcat agcgctcatc tgctcgcaga ctagcaattt
     2701 cttcgctcag tttgactacc tcacgtggtt cgatatagac ggtgtttcca ctagcagaaa
     2761 tatcatgaac gacacctgca atcttattgc ggtaggtgtt tttgactggt aaaacctgac
     2821 ggccatttct gctagcaaca attccttctg tcaacatctg cgctttttgc ttgagcaagt
     2881 cttgtaaaac atcgcgtacc cgactctcgc tatcatgtat ttttcgacgg attcgcgcca
     2941 attcttcact ggcaaaattt tcaatgaaac ccgcatcatt aaaggcctga agatttcctt
     3001 gtaattgcgg aaaatcatgt aatttctcaa accaaagggc taattcttcc aagctgacat
     3061 tttccagatt ggcgtaaaaa ctttgaagtt ctcggctggc aagaagcacg cgtttcaaga
     3121 gtaggaactc ctcgatattg agagccgctc ccatctccaa cctcttgcag actcctgcaa
     3181 tttccttagt tgagagaata gtaaaatgcg gttgctcgac gaaaagagcc tgcatttcct
     3241 tcatctcagc aaaagcctgt ttgattttat ctgctttggc agtcggaccc agctgtctca
     3301 attgctccaa gccctgctcg gtcaacaaat gaggctcaaa caaggccttg accttatcga
     3361 actctaatgt ttctaatatt ttcttattca tctttatttc cttgtctttg aatgtctagg
     3421 tgtggtagct ttttacattc tgatagattc gagtcaaatc tgtaaacaaa gggctaggaa
     3481 aactcctgcc ctttttatcc gattaaattt gtcacccaga tttgtttgag ccaactggtt
     3541 gttatcggta tgctctggat gatgtgtttt gcgacgatac tcttttcaag aggattttgt
     3601 ataactgcca tggggatggt cgccaagatt gtcaaggcca tttgcaagac aaataaggtc
     3661 accaacatgg acaagatacc tgctgaaact tggaacaact taccacccag ttttttgcta
     3721 ggaatcaagt gtaagagaag accaagcaaa cgaccaatgc tatagacaat cccaaataca
     3781 agcaagtagc cgatgcctgc ataaaagacc ttatccagct gaaagagttg atccgatggg
     3841 aaaaagaaag tcccctgacc ttcctgcgaa tttgcataag ggagcaataa atggaattgc
     3901 tctccaagcc ccttataaaa ctggccagcc ataaaagccg atgccatggc tgaaatcagg
     3961 taataaacct gtaagagcag gcctctccga tagccgatat aaaatcccca aaccaagacc
     4021 aatagaagaa ggaatgaaat cataaggaat cctcaatctt gctctgttct tgcttacaag
     4081 tcacaagctt gtgacggagt tcttctagct cttgctcctt atcgtcaaat tcaatctcac
     4141 ggctgagctg agttgataaa cagttgactg ccaacaaaag agcgattgtt tcatcatctg
     4201 cgctaggcat ttgttcttta attgcttggt atttttctgt cgcaacctta gcgatttcct
     4261 ccataaaaag gttatcatgt tcgcttgtca aggttaacga ttttttcccg aatgtaaatt
     4321 tgaatcgatt tagatttgcc ataaaattca cctcacgata ttataccaaa attcgctaat
     4381 tttgtcagtt tttacaaatt ttactgcttt tgtggtacaa tagaaactat ggcaagtatc
     4441 acactcacac caagcgaaaa ggatattcag gcttttcttg aacactatca aaccagtctg
     4501 gctcctagca agaatcccta tatccgctac tttttgaaac tacctcaagc aacggtttct
     4561 atctatactt ctggaaaaat cttgcttcag ggtgaagggg ctgaaaaata cgccagtttc
     4621 tttggctatc aagctgtaga gcaaaccagc ggacaaaatc ttcctttaat tgggacagat
     4681 gaggtgggaa atggttccta ctttggtggg cttgcagttg tggctgcctt tgtcacacct
     4741 gaccagcacg actttttacg aaaactcggt gtgggggatt ctaagactct gaccgaccaa
     4801 aagatccgtc agattgctcc tattctcaag gaaaaaatcc agcaccaggc actccttctc
     4861 tcacccagca agtacaacga ggtcatcgga gaccgctaca atgctgtttc ggttaaggtt
     4921 gccctccata atcaggctat ctatctcctc cttcaaaaag gtgttcagcc tgagaaaatt
     4981 gtgattgatg cctttaccag tgctaaaaat tatgacaagt acttggcaca agaggccaat
     5041 cgtttcagca atcctatcag cttagaagaa aaggctgagg gcaaatactt ggctgtcgca
     5101 gtttcttctg tcattacgcg tgatctcttt ctggaaaatc ttgaaaattt gggacgagaa
     5161 ctgggttatc agcttccaag tggagctgga acggcttctg acaaggtggc tagccagatt
     5221 ttgcaagcct atggtatgca gggactcagc ttctgcgcca aattgcactt taaaaacact
     5281 gaaaaagcga aaaaacgctt agaaaggtaa gttatgaatt catttaaaaa tttcttaaaa
     5341 gagtggggat tgttcctcct aattctgtca ttactagctt taagtcgtat ctttttttgg
     5401 agcaatgttc gcgtagaagg acattccatg gatccgaccc tagcggatgg cgaaattctc
     5461 ttcgttgtaa aacaccttcc tattgaccgt tttgatatcg tggtggccca tgaggaagat
     5521 gggaataagg acatcgtcaa gcgcgtgatt ggaatgcctg gcgacaccat tcgttacgaa
     5581 aatgataaac tctacatcaa tgacaaagaa acggacgagc cttatctagc agactatatc
     5641 aaacgcttca aggatgacaa actccaaagc acttactcag gcaagggctt tgaaggaaat
     5701 aaaggaactt tctttagaag tatcgctcaa aaagctcaag ccttcacagt tgatgtcaac
     5761 tacaacacca actttagctt tactgttcca gaaggagaat accttctcct cggagatgac
     5821 cgcttggttt cgagcgacag ccgccacgta ggtaccttca aagcaaaaga tatcacaggg
     5881 gaagctaaat tccgcttatg gccaatcacc cgtatcggaa cattttaaga aacctaagag
     5941 gccgagaatc accaatctca gcctcttctt ctatcgtgag aaaatgattg gtaactatct
     6001 aaacttacca gaacagaaac acctcaactc tcacctattc atgcaaagga attttatgga
     6061 agtttatttt tcaggaacca ttgaacggat tatttttgaa aatcccagca atttttatcg
     6121 catcctcctc ctagaaatcg acgatacgga cgcagaggat tttgatgact ttgaaatcat
     6181 tgtcacagga accatggctg atgtaattga gggcgaagac tatacttttt gggggcaaat
     6241 tgtccagcac tccaagtatg gagaacaact gcaaatcagt cgttatgatc gcgcaaaacc
     6301 aactagtaag ggcttggtca agtacttttc aagtagccat ttcaagggga ttggtctcaa
     6361 gacagctcag aaaatcgtgg atacctatgg cgaaaatacc attgacgaaa ttttgcaaca
     6421 cccagaaaag ttagaaggca tcgcaggact ctctgccaaa aatcgcgagg ctttcgtctc
     6481 cactctccgt ctcaactacg gaacggagat ggttttggcc aaactagcca actacggcat
     6541 tcccaacaaa ctagcctttc agattcaaga cttttacaag gaagaaaccc ttgatgtggt
     6601 tgaaaattat ccctaccagc tggttgagga tatcaagggt ttgggcttta ccattgctga
     6661 ccaactagct gaggaactag gcatcgaaag tcaggctcct gaacgcttcc gcgccggtct
     6721 agttcacagt ctttttcagg cctgtatgga aacaggggac acctatgttg aagcacggga
     6781 tttgctggaa caaaccctta ctctccttga gtcttcccgt cccgtggaac tagaccccag
     6841 ccaagttgcc caagagctct cctacctgat cgaagaagac aaggttcagc agattgatac
     6901 caagatcttt gacaacagcc tctttttcgc tgaggaaggc atccgcagtc acttggttcg
     6961 tatccttgaa aaaggaaaac agaagagtca tgatttaaaa accattcaaa aacatatcac
     7021 tactatcgag caagagcttg gaattgagta tgataacatt caaaaacagg ctatctgtga
     7081 tgctatccag aataaggtct ttatcctgac aggtggacct ggtactggta agacaactgt
     7141 tatcaatggg atcatcgctg tttacgccct gttagaggga cttgacttca ggaagaaaag
     7201 caacctgccc attcttcttg ctgctccaac tggtcgagct gctcgtcgca tgaatgaatt
     7261 gacaggtttg cctagcgcga ccatacaccg ccacttggga atgacaggtg acgatgatac
     7321 cagtcatctg gaagattacc tagatgctga ctttatcatc gtggatgaat tctctatggt
     7381 ggatacttgg ctggccaatc aactcttctc caatatctct tctaacagta agatcctcat
     7441 cgtaggtgac agtgatcagc taccttctgt cagtcctgga caggttctag cggatctgct
     7501 tcatattcct ttgattcctc agactcgctt ggaaaaaatt tatcgacaaa gcgaagaatc
     7561 aaccatcgtc accctagcta gtcagattcg acagggcatc ttgccagctg atttcaccca
     7621 aaaaaaagct gaccgttcct actttgaaat tgctagtggc catattcctg ccaccattga
     7681 aaaaatctta ggtgccgccc tcagaaatgg tattcctgcc cgtgatatcc aagttctggc
     7741 tcctatgtac cgagggacgg cagggattga tgctatcaat cagctcatgc aagacctgct
     7801 caatccccca caaaaagatc aactcagttt tgaagctcct cagtgccact atcgtaaggg
     7861 agacaaggtc attcatttgg ttaacgatgc tgaaatcaat gtctttaatg gggatttagg
     7921 agctatcaca gacctgattc ctggtaaata caccgaatcg aaacaagacg agattgtcat
     7981 tgattttgat ggtaatgaag tctcttaccc ccgtaacgaa tggtacaaga ttcgcttggc
     8041 ctatgccatg agtattcata agtctcaggg aagtgagttc ccagttgtca tcctaccgat
     8101 tactagtgct agccgacgta tgctggagcg aaatctcatc tacacagcca ttacacgtgc
     8161 caaaagcaaa ctcatcttac taggcgaatt acaagccttc gactatgcta cccaacacat
     8221 cggaactgcc cgaaaaacct atctgattga acgcttcagt gatctactgg agaatgttga
     8281 agaaaagcaa caagctgtct ctgaaacagt cacatcaagt gcctctgaac aatcctacat
     8341 cctaaccgaa gaaaactggg acagcattcc agccatgatt gggattacag acacagacct
     8401 caaagagatt tttggaaaat agtacatcag aaaacccacc aattcaggtg ggttttctgt
     8461 ttattaagat tattttactg ttgctgtgct tgtgatcaat tcaacagctt ttttgatagt
     8521 gatatcatgt ttcaacatgt cagctgaaag caagttttga acttgtgcaa cttccatgtt
     8581 gtagtctgct gccaattgct caacttcttt ttggatttct tcttctgaag catcaaatcc
     8641 ttcagctttg gcaactgctt cgataacaag gttagtctta gtacgtgact cagcttctgc
     8701 ttggtattgg ttgtgaaggt cttcttgagt agttccagtg atttggaagt acatgtcagg
     8761 gttgatccct tgacgttgca agttcccaag gaattcattt actgaacggt gaacttcttc
     8821 atggatcatt tcttctggaa gttctacgat ttcagcgttt tctacagctg tatcaattgc
     8881 tgcaccttca actgcatctt tgtaagcttc ttctttagca gcagccaatt ctttgcggta
     8941 tttttctttc aagtcagcaa gtgtttcaac ttcttcatca atgtcttttg caagttcatc
     9001 gtcaagagct ggaacttctt tagcttttac ttcgtggata gttgtcacga atttagcttc
     9061 tttacctgca aggtcttctg cttggtagtc ttctgggaat gttacgataa catcaacggt
     9121 ttcgccagct gagtgaccta ccaattggtc ttcgaaacca gggatgaatt gacctgaacc
     9181 aagtccaagt gagaagtttt caccttttcc accgtcaaat tcaacaccgt cgatagaacc
     9241 aacgaagtcg atcacaacag tgtcgccgtt ttcagcagca gcttccttga taaccaattc
     9301 agccagattg ttgcgttcgc gttcgatacg ctcttcaaca tcagcgtcag ttacttcttt
     9361 ttctacatca actgatactt caaggttttt gtagtcaccc aattttactt caggttttgt
     9421 aacgacttca gcagcgataa cccagtcttg acctttttcc attgaagtta cgtcaatttt
     9481 tggttgggca accacttcaa gaccagcttc ttttacagct gcttcataag cgtttggcaa
     9541 aagagcgttc ataacgtctt ggtaaagtga ttcttcacca aattttttat cgaagatagg
     9601 acgtggaagg tgacctttac ggaaacctgg aacattaaga gatttcttca ctgacttgaa
     9661 gacacggtcc aattctggtt tgatttggtc ttgagagata gtgaaagtca agacaccacg
     9721 gtttgtttct ttgttttcaa atgatacaga cattctgtca tttctcctta aaatttttta
     9781 aatacagtct attataacat tttctataaa taaaatctag actaatgcag acaattatag
     9841 acaacaagcc tttttcctaa ctaaaacact cataaagtat agacaatttt agactacttt
     9901 ggatatcttt tggttagtca ttttccaaaa ctaatttatc taatttttaa gttatatttg
     9961 acttcatctt ctcagtaaca tgagtataaa cacttaaaat ctttgtttca ttagtataat
    10021 ctacacgatc cattatcgct attataggta cttccaattc agcaagcaaa cttatatgcg
    10081 aatatctaaa aacatgagca gtcaatacaa aatcatcttt cttaatttca cttttcctaa
    10141 acctgttttt caaaaagtaa ttgaaacaag ttatcattaa gggagaacca ttatttgtaa
    10201 atatataatc accttcttct aaaagaagat attcttttaa aatttctaac actctatcac
    10261 taataccaat tactctatat gaagctaaac ttttcggact atccaaaaac acttcgttat
    10321 tggacgatta cattatagta aaacgaaata agaacaggac aaatcgatca ggacagtcaa
    10381 atcaatttct aacaatgttt tagaagtaga ggtgtactat tatagtttca atctactata
    10441 caagacgaaa ttgaagaaat ctttccatta taaaacgcat attatcaagg tttttaaaca
    10501 cctaataata tgcgtttttt cctattttaa agacttttat ccacctatta tacaaagtta
    10561 agtatccatc acagtttaca attagccttc attacctaac ccattcacca tccttcaaga
    10621 gagtaacctt taagaaccga ataaataaat gacaaatttc gttcatttaa tttaactgca
    10681 ctgttaattt gattagctcc atctcctaaa gtatgcactc ctactacacg gtgactagca
    10741 tcataaactg tagatccact agacccctct aaagtatcaa cttggtaatc caagaacatg
    10801 ccatcatcac ttaaaacttg ttttttatct gtatacattt gatgaatttt aaaattatat
    10861 gatggatagc ctgtgatagt cacagttatt cctgtcaaat ttttttgact agtaggaaaa
    10921 cccaaagtcc ctaattttgc accaatgggc tcttctagaa ttaataaagc caagtcatat
    10981 tcccttgcat ccttagaatt taaatttcta aattccttca aataacaaac ttcctttact
    11041 ttgatctttc caaatagttc ttgacttgga ctaacagccg gaagaacata aatatcatcc
    11101 gcttctttcc catagtcatg tctgtagtag ttgtgagccg ctgtaattaa cacattatct
    11161 ttaataaaat tcgcacttcc cctcccttct acattcattc catcggctac tccataatac
    11221 ttagataaaa ccatagctga agtcgaatac ggatactgta aagtattatc aattttaatc
    11281 aaatcatcat taccgataat acttctgatt gcttttggta gtatgaacca tacgttggtg
    11341 aaatctcaga taatgaagaa tcattagacc ctggaccttt ttctagtgtc tcacttacct
    11401 catattcttc acctgtacta gaaataacac tcaaagcaga tactgtcgat aactggctag
    11461 ccaataaagt actcgcaata attgaaatac ccaatttttt ataaacagtt ttcttcatta
    11521 ttgtatcctc ctaatgtaat tatagcgtac tattctaaat ttcttaatct actatagaat
    11581 caagaaatct accaccttct ttaaataccc tccattatca cataaacagg taaacttttc
    11641 aattaatgac tgcgcttttc aatcacgcta gaggtactta cttgcttctt tgatactaag
    11701 ttcagccatt ctttccttgt ttttctcaat aaagcatgtt acccaagtgg gattcgtttt
    11761 ggagtagtct cgcagagtcc agccaatggc tttattgata aaaaattctg tttggttcaa
    11821 gttatgaagt agaatctttt ccattaattg agtattggtc ttctcttttc ttaacaactg
    11881 gtggtcaata gcgacacgtc tcagccagat attatctgat aggctccatt ttatactcaa
    11941 tgaaaatcaa agagcaaact aggaagctag ccgcagattg ctcaaaacac tgttttgagg
    12001 ttgcagatag agctgacgtg gtttgaagag attttcgaag agtattaaga ttatttcttc
    12061 tagttcaggg tgttcataca ccaaactccc tactactcga tctaggatat ctaccgtgtc
    12121 ccaccaggat tttgtcacga ctaactgctc tagcttaggc aaatcggttt cctttagata
    12181 agactgcatt gttttcaaat agttagcagc cacatattgg tattttctag gctccttttc
    12241 ccagcaagtg tctgcaaaat cccaatcgat aatctttgtt tttttcgctt ctagtaaata
    12301 tttttataga gtttatttct ttcaggcacc gcaataccta gaaaagaaaa ttgatggcgc
    12361 atataggctt ccatggacct tgctttttta gagtcttttg ctgcttctag ctcctcaagt
    12421 aaatctgcta aactcatcta aaactcatct tgccccacca aatggtgctg aaaggcatag
    12481 acagccgcct gggtacgatc gctgacttca agtttggcaa gaatgttgga cacgtgggtc
    12541 ttgaccgtct tgagagagat aaagaggtca tctgcgatgc gctgattttc gtagcccttg
    12601 gcgatgagtt ggagaacatc tcgctcacgc gcagtcaatt cttcatgaag ttccatatga
    12661 ttgcggtggt attcaacctt cttgctaacc tcttgctcaa tggccagctc gccagcagct
    12721 accttactga cggcatgaag caattcatct gcactagaag tcttgagcat atagcctttg
    12781 gcaccagcat ctaagactgg catgattttt tcattgtcca aataagaggt cacaatcaaa
    12841 atcttggctt caggccattc tttaaggatt gctaaggtcg cgtcaatccc attcatctca
    12901 ggcatgacaa tatccatgac aatgacatct ggacgcagtt ccaaggccaa gtcaatccct
    12961 tgagacccgt tggacgcctc acccacaact tctacatcgt cttggaggtc aaagtagctt
    13021 ttcaaaccca aacggaccat ttcatggtca tctactagta aaattttcat ctttactcct
    13081 ttatcattcc ttatctaaca ggggaatacg gatatcaact gccagccctt gcttgggagc
    13141 tgtcaagagt tgaactgttc cagccatatc ttcaaccctc tccttgatat ttcgcagtcc
    13201 ataactcaag tcgtctaagc ttcctaaccg gaaaccaatc ccattgtcca ccaccttcag
    13261 ttgcaattca acatctgtct gatagaggta gacatctagg caagatgcct gggcatggcg
    13321 gagggtattg ctaatcaact cttgcaggat acggaagata tgctcctcga ttttcttagg
    13381 caatttcgtc atattctgct tgagactaac cctaagatca ctcttgtcct caagctcttt
    13441 taagagaatt tgaatccctt ctatcaagct cttctgctcc agttcaactg gtcgcaaatg
    13501 caagagcaaa acccgcaaat ccttctgggc agtttctaaa atagctgtga cactctgcaa
    13561 ctggatctgc atcttttctc tatccaattt caaagcctgc tgactgatac ccgataaaat
    13621 catgtgggcc gcaaacaact cctgactgac tgtatcgtgc aaatcccgag caattcgctt
    13681 ccgttctttc tcgatgattt cctcttcctg agcaaggcta tgattttcag ctttttgaag
    13741 agcttctgtc aaaaggttaa gtttacctga taaggacttg aaactggcat ccaaatctgg
    13801 atctgcaacc tgaaccactt cttgccctgc caataaacgc ttgagattag cctgcatttt
    13861 tcttagagaa agctcttcga tccctcgcca aaacagggct aagagacagg ttatggacat
    13921 gctgaaaacc aacaataaaa agacaaattt ttctgttttt tcgacatcgt gcaaaaagat
    13981 agaccagtca aaatcaagta tttccagcaa gctgtgggag aaaaaaaaga caaacaggaa
    14041 ggaggtgaga gcaataatga cataggcttg ttttttcatc ctctaaccac ctccacatca
    14101 ccaatcatag tggtcaagaa aatcttgaca ctcttgttac tcttgagata gtcttttgtt
    14161 tcttgatgat agtgttcatt gcggagggct cgcttgggct ggttgaaaaa agtcaaatcc
    14221 ccatagagac agttaacgct gagactgact tccacatcta caggtacgat gattttggtc
    14281 gttcctacca tctttctgag gataatgaca ttgtcatgat tggttaagat gaccctctcc
    14341 agatgaatag tgtccttgcc catgaagcga aagagattga tatcatcgaa ttggcaagtc
    14401 tggtagcttg aaaaatgatg aagatttcca aaccaacgat ttttctcctt cttaaccgtc
    14461 acgacctctt caaaaaccaa attggtctgc tctttttcct ggttcatcat cgggtaaaga
    14521 agaaagaggc tatagataac cgcaacaaaa atagctagaa tcacaaaagg attgagcata
    14581 acgatgaaaa agaagagaat ggttgccgct actaaaagaa gattatttcc ctctttacca
    14641 gtgtagtagc gaatcaaaag caaaaagagg aatagtatca gcagaaaacg cgaaaaatgc
    14701 tctgatacca tcaaaatcag agctcctgtc agaagacagg cttcgataaa taaaaagatt
    14761 ttaaattttc tcataggttc atcctctccc ttctatttta tcacaattca aaaaagtcac
    14821 ctcagtctga ggatggaaaa aaggcgctgg ttacgccttt ttcatctgat cctttgcttc
    14881 ttttaatttt ccataaagaa gatagtctac tttttgtaga tctgctatgg tggcacagtt
    14941 aagggaacac ataatcaagc gtaggtctgc tttccagcct tggacaatgc caatcacttc
    15001 ttcaactgtg taggtttcaa ccaattccag aacggttcgt gacaatccca cagacttagc
    15061 accaaaaacc aagcacttaa tcatatccag cggattccga acccctccac taaccaagag
    15121 ttcgacctta tctttccatt cttgggcatt gagaagggcc tgcatggtag actgacccca
    15181 ttgattgagg taatcacgct ggccactacg acggttttcg atataggcaa agctggtgcc
    15241 accacgaccc gataggtcca ctgtacgaac accgaattca taggctcttt cgattgtctt
    15301 ggcatccatt ccaaagccca cttccttgag gacaatagga acgggaattt gcttgctata
    15361 atctgctaga tgcgattgcc agcttctaaa cttcctttct ccctcgggca tgagtaattc
    15421 ctgcatgaca ttgacatgca cttgcaatag aacaggattc atctcttcta cagtctgaag
    15481 tcctaactcg acaggtttgt ccaatccaat attggttcca aggaggagat tgggatgact
    15541 agacttgaca gaaaaagaat catccgttgg atttttgagg gctgcgctat aagaacccgt
    15601 tacaaataaa ataccacagg attccgccac ctgagccagc ttttgattga tttctcttcc
    15661 cttattactt ccaccagtca tggcattgat ataaaaagga aagtcccact ttcgaccagc
    15721 aaactctgtc gaaagatcga tttcatccag attgtaaaga ggcaaggaag aatgaatcag
    15781 ctccacctca tcaaagctat tataggaact tttctgctca agggcataga ggatatgctc
    15841 gtccttacga tttgtcgtca tgtcctatcc tttcttgata taagagctca atccccagat
    15901 cggcccaacg attttttaag gtttcggttg attgcgcatc aaaactcaag gcgatgccac
    15961 agtcaccacc accagcacca ctactcttgg caacggcctg caaatcttga ctggcttctt
    16021 tcaactgtct aagcaaaggc gtgtaaatat ctgtactcaa gccttctaaa agcttgctgg
    16081 ctacttctac ttgctcgata actttttcgg ctttcccctg ctccaaggct tcgaccaaag
    16141 aaaccaccgt ttcttttgag gaagttaaaa aattttgatt gatattttgc ttgatttgct
    16201 ggaccatgtg actcgataca gccacttcct tggtccatcc cactaagaaa tcacattcta
    16261 aagttggttt cacttgtgag ataaaaaatc cccaatcacg ctccagaact gtcgccaagt
    16321 tttcttcttc taaccaagca gccaccttct ggcgatcaaa tgactggtag agaaccaaat
    16381 cctctgccac aatacaggca aggtcgccca tggaaccatt gtctcctcgc ttgagcaaga
    16441 cagcgctagt cagcttgaac aagagattct gatcaaccga aagattatag agagccagta
    16501 aagccttgac aaccaagaca acaacgctgc cactagaacc tagaccaaac tttttccctt
    16561 ctcgttccat tttgccacag atttttaggg aaaaagatct taaattctga ccgcgaacag
    16621 cgaggaagtc tcccatcaaa gcaatcgttt cttgaatcaa gctgtagtca ggattaggcc
    16681 ttaagtccac tgcgaaatca aacatatctg aatagatacg gtagctgtca gaaaaagcaa
    16741 tttcagccct catatagatg ggaatatcct ttatcaaagc taactgccct ggctctaaaa
    16801 tagcatattc acctgcccaa tagagttttc cgcaagtttt aacagcaatc atcttgactc
    16861 aaatcctttg tttttgacac aatcaagcga taacgctgac cgaaaatttc tgataaatgc
    16921 tccaagtctt tctcctgaca gaagacctta acattgggac cagcatccat ggtaaagtag
    16981 caggcctctc ctttctcacg aagctggcga acaaagtcca tagcctcata agaggcatcc
    17041 gtcagataag aaaaggctgg actagcagtc tttgtcgtag catgcatagc cagggcattt
    17101 ttctccgtta attctccaat cttggcaaaa tcattttcct tgagataaat cagcatatcc
    17161 tgatagtcct tctcagactg acgaacccag tcgtcgaaag tcgtcgaggt ttccacacaa
    17221 agtttcatcc cgtcacggct agagattggt tttttcttgt cctctagcac caacataatc
    17281 atagctagtt tcaagtctgt ctctacaggg taaatttctc cactatcctt atcccaggct
    17341 cctagtggtc cataaaaact ccgagaagaa gagcctgagg caaatttggc ttcctgtgcc
    17401 aactgacttc tatccaatcc aagtttgaaa taagcattac aagccttgac cagggcggac
    17461 aaaccactag aacttgagga caggcccgct gccgtaggca tattgttttg agtatcgata
    17521 cggacaaagc cctcaccagc tggacgataa cggtcaataa tcttactcat cttggcatgc
    17581 tcgacctcat tttgtagctg accattgatg taaaattcgt cagctgttac attggctggt
    17641 aaaggcgaca aggtcgtctc tgtatacata ttttccaaag ttagagaaat actgctagta
    17701 gcaggcacca tctctttttc ttttttcttt ccccaatatt tgataatagc aatatttgcg
    17761 taggaacgta ctgttacagg ctctctatcc atgtctgaac agctcctttc tcttctaatc
    17821 tttctgctag ttcttgtgcg tgtgtcaaat tggttaccaa ggctatgata caacctccta
    17881 gcccaccacc gctcatcttg gcacccagag caccatggct aagagtcgtt tcaaccaaaa
    17941 agtctgcctc agggctactg actccaattt cttttaaatg taaatgcgct tgactgagga
    18001 tttgtcccag tccttcagca tctttttgtg aaatcgcaac ttctgcttgc tgggttaatt
    18061 ctcccaaggc atgcaaaaac ggtagggcat ccttgccctt attttgaacc acttggatgg
    18121 cttcacgagt atgaccataa acacccgtat cggcaatcac caaataggcg gataaatcca
    18181 tctcaagttc tgtaaatcct acgttcttga taaagcgaat aggttggtca ctgagacagg
    18241 tcttagcatc caaaccacta ggattcatat gggcaatcat ttcagctcga ttgaccaaga
    18301 tttctagtac atcatgaggc agatcagcct gatagtagtc aaataccgca cgaatggccg
    18361 ctatgctgat agccgctgac gaacccatcc cccgtttctc agggatagcc gagtcaatct
    18421 cacaacgaat gcaggcttct gtgatatcca aatactccag tgaggcataa accgccatgg
    18481 acaaggtatc ctcctcataa aggcgccaag gactctctgc aggaactacc ttacaggtca
    18541 cctccacctc caaaagaggc agggaaatgg caggataacc gtaaacgacc gcatgttccc
    18601 ctattaaaat tatcttacta tgtgcctgac cgacaccaac tttttttgtc attttttcct
    18661 tttactagac gaaaaaacgt cttatttttc atacaagtat taattctttc ctatctattt
    18721 tattatattt tcacaaaaaa agcgattgtt tccattcaca atcgcttctt tcattattga
    18781 acccattcgc cattatagtt gacagaatag ccatctacgg tcgtattcac tgccaaggca
    18841 cctgagctat aagcgtagta ccatctgcca ttgacctgga accaacctgt cgtcatagaa
    18901 cgacgaaaga aactccatac cattaagtaa agaggaaagt cgtgagggag catgcgccat
    18961 tgacaacttg ttttagtgac gtacaaagtc tcattaacaa gtactcgttt cggccattta
    19021 taggtgcggt gtttggagaa atagggttca atcttagccc attcttgatc gtttaaatca
    19081 gtatcatatg ctttgcgtgt cataactcta gtttaacatt tttttgtgaa tacaggttct
    19141 aaataatcga ccacgaaaat ttcttaagtg gaaaacgcct tatgaagtat gctacgggaa
    19201 agttatgcac ttaatttgac aattcaagat gtaaaaatat a
//
LOCUS       DAVLCS010000036        18478 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLCS010000036 DAVLCS010000000
VERSION     DAVLCS010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.036"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            32..301
                     /gene="blpJ"
                     /locus_tag="VXC78_001566"
     CDS             32..301
                     /gene="blpJ"
                     /locus_tag="VXC78_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEV0583614.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            370..618
                     /gene="blpK"
                     /locus_tag="VXC78_001567"
     CDS             370..618
                     /gene="blpK"
                     /locus_tag="VXC78_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpK"
                     /protein_id="HEV0583615.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAVVAAL
                     GCAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            862..1011
                     /gene="blpO"
                     /locus_tag="VXC78_001568"
     CDS             862..1011
                     /gene="blpO"
                     /locus_tag="VXC78_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV0583616.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1115..1234
                     /locus_tag="VXC78_001569"
     CDS             1115..1234
                     /locus_tag="VXC78_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0583617.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            1702..2073
                     /locus_tag="VXC78_001570"
     CDS             1702..2073
                     /locus_tag="VXC78_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583618.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLTSIL
                     VTVYLTREMRLREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQLIAYI
                     GAILCLIIMLLLIWGLKYYKK"
     gene            2702..3085
                     /locus_tag="VXC78_001571"
     CDS             2702..3085
                     /locus_tag="VXC78_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV0583619.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            3137..3826
                     /locus_tag="VXC78_001572"
     CDS             3137..3826
                     /locus_tag="VXC78_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0583620.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            3868..4101
                     /locus_tag="VXC78_001573"
     CDS             3868..4101
                     /locus_tag="VXC78_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583621.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            4252..4863
                     /locus_tag="VXC78_001574"
     CDS             4252..4863
                     /locus_tag="VXC78_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0583622.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            5024..5818
                     /locus_tag="VXC78_001575"
     CDS             5024..5818
                     /locus_tag="VXC78_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV0583623.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5815..6450
                     /gene="trmB"
                     /locus_tag="VXC78_001576"
     CDS             5815..6450
                     /gene="trmB"
                     /locus_tag="VXC78_001576"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV0583624.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6576..7055
                     /gene="rimP"
                     /locus_tag="VXC78_001577"
     CDS             6576..7055
                     /gene="rimP"
                     /locus_tag="VXC78_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV0583625.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDGLTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            7099..8235
                     /gene="nusA"
                     /locus_tag="VXC78_001578"
     CDS             7099..8235
                     /gene="nusA"
                     /locus_tag="VXC78_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV0583626.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            8257..8550
                     /locus_tag="VXC78_001579"
     CDS             8257..8550
                     /locus_tag="VXC78_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV0583627.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8543..8842
                     /locus_tag="VXC78_001580"
     CDS             8543..8842
                     /locus_tag="VXC78_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV0583628.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8859..11651
                     /gene="infB"
                     /locus_tag="VXC78_001581"
     CDS             8859..11651
                     /gene="infB"
                     /locus_tag="VXC78_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV0583629.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11902..12252
                     /gene="rbfA"
                     /locus_tag="VXC78_001582"
     CDS             11902..12252
                     /gene="rbfA"
                     /locus_tag="VXC78_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV0583630.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            12531..13310
                     /locus_tag="VXC78_001583"
     CDS             12531..13310
                     /locus_tag="VXC78_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583631.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLAGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLCAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIIAGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            13312..13494
                     /locus_tag="VXC78_001584"
     CDS             13312..13494
                     /locus_tag="VXC78_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583632.1"
                     /translation="MNPIKAFDKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIRPEERE"
     gene            13454..13642
                     /locus_tag="VXC78_001585"
     CDS             13454..13642
                     /locus_tag="VXC78_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583633.1"
                     /translation="MRLGGSLGQRRENEIFFGLLAILFIKPIIGIVKFFWMIISFAVQ
                     LLFYKILFKILDWLFKLI"
     gene            complement(13937..14014)
                     /locus_tag="VXC78_001586"
                     /pseudo
     CDS             complement(13937..14014)
                     /locus_tag="VXC78_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14045..14278
                     /locus_tag="VXC78_001587"
     CDS             14045..14278
                     /locus_tag="VXC78_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV0583634.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            14278..15612
                     /locus_tag="VXC78_001588"
     CDS             14278..15612
                     /locus_tag="VXC78_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV0583635.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTIAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            15622..15876
                     /locus_tag="VXC78_001589"
     CDS             15622..15876
                     /locus_tag="VXC78_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV0583636.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            15972..16367
                     /locus_tag="VXC78_001590"
     CDS             15972..16367
                     /locus_tag="VXC78_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0583637.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            16780..17229
                     /locus_tag="VXC78_001591"
     CDS             16780..17229
                     /locus_tag="VXC78_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEV0583638.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            17216..17773
                     /locus_tag="VXC78_001592"
     CDS             17216..17773
                     /locus_tag="VXC78_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0583639.1"
                     /translation="MARTELPDQIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDAQGNCCDSLIYGLLKSEWEE"
     gene            17775..>18478
                     /locus_tag="VXC78_001593"
     CDS             17775..>18478
                     /locus_tag="VXC78_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV0583640.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNA"
BASE COUNT         5631 a         3201 c         4163 g         5483 t
ORIGIN      
        1 acaaattgaa aataaaaagg aggtattcat catgaataca aaaatgttgt cacagttaga
       61 ggttatggat actgaaatgc ttgcgaaagt tgaagggggg tatagctcca ctgattgtca
      121 aaatgcactg attacaggag tcactacggg aattataact ggtggaactg gagcaggttt
      181 ggccacttta ggagtagctg gacttgctgg tgcatttgtt ggagcacaca ttggtgcaat
      241 tgggggtgga ttaacatgct taggaggtat ggttggtgat aaattgggac taagttggta
      301 agacttatag taaaattatg aggattctat tctgatttat tttagttttt taaaaaagga
      361 gtatttgtca tggatacaaa aatgatgtca caattttctg ttatggatac tgaaatgctt
      421 gcttgcgttg aaggtggcgg atgcaattgg ggagattttg ccaaagcagg tgttggagga
      481 gcagctgtag ttgctgcttt aggttgtgca gcgggtggag tgaaatatgg gaaaattcta
      541 ggaccatggg gcgctgcaat aggaggaatt ggaggagcag tggtttgtgg atatttagcc
      601 tataccgcta catcataaaa atgaaagcta aattttatga aggctatatt ctttattatt
      661 ctcttcgctt ttcaaaccta tcttatttat ctatccataa gtatctctga taaaaaacaa
      721 aagactattg aattaacatc attgaattgt tttgtcatat tatttctaat ctatgataaa
      781 ttaatttttc tctttattgc ctatgttttt ttgataattt ttatattaaa cttgttccgt
      841 aactgaaaag tgacatacta tatgaataca aaaatgatgt cacaattttc tgttatggat
      901 aatgaaatgc ttgcttgcgt tgaaggtgga gatattgatt ggggaagaaa aattagttgt
      961 gcagcagggg ttgcatatgg cgcaattgat gggtgtgcaa caacggtttg acatttctat
     1021 tgggaccatt tgctatagga ataggtgtaa ctggtgctgc aggtggagct atacttggag
     1081 gtgtagccta tgcagcaaca tgttggtggt aattatggat tttaaaagtt ttattattgg
     1141 tttagtagtt ggtatatttg gtccttatat ggatgactta attagaaaaa tattttcaaa
     1201 atcttccaaa aaggatacgg atagtactct ctaaaaaata aatttctccc ctgtatttgc
     1261 tagcttaatt tacaggggag tttctttaat attgtttcgc ctgtcaaaat gatatgtgat
     1321 agcaggatga aaagtctaca aacaagttgg tatcaataca atataaagag gaaagtatgt
     1381 ttttcatgct tgctttttta atttttacaa ttcaagaggt tttgatgacc atttatgatt
     1441 tgagtgatcc aaggtcaaaa taagtgctat actagcagtg taaatgttct tgctcaacta
     1501 agataaatcg cacatttagg aggaaaactt atgaagaaaa aaatactgat tattttcgtt
     1561 ctgtatctga tcatgtccat ctttctttat ccgcttaggg agagtatttg gtataatcta
     1621 ttttatacca tagcctatat gattgcggtt atgatctatt tttctttaat taaaaagaaa
     1681 gaaaagaaat gaaagatttt cttgattaaa aagaatcata ttctttgtga gattgttcct
     1741 gggtcagttg cctttgcttg tttctactta tctatttcta tttcgtcagt tttccaattt
     1801 cttttagtag ttattaactt gacttctatt ttggttactg tttatcttac tagggaaatg
     1861 agattaagag agtttgaaga tgatgatttg gttagtccta gaaccaatca actcatgttt
     1921 atcggcttga caggctttat gtctattatt tgtttgtata gaggtatcac agcaggagaa
     1981 tcttatcaac aactaatcgc ttatattggt gctattcttt gcttgatcat catgcttcta
     2041 ctcatttggg gtttgaagta ttataaaaag taggggctaa tgaagttttt gcaatttagg
     2101 aggtttcgat gacaattcaa gatttggatg aaaaatttta aaaaacaatg atatactaaa
     2161 cttgtcaaag ttgcaacggg tgctgctaca ttatgttaaa aatcgctctt gattgataag
     2221 ttggatttgt taggaaagga gtaaataatt atggataaga aaaagatagt ttcgactata
     2281 atatgtatag tatttcttgt agtgtcagta gataattttt ttagagactt aaccccgtta
     2341 ctgttcattt taaatattat tggcctgtct tgcttttcag tgctaacata cattaacata
     2401 aaagagatac tcttaaatat aagtaaatga tgatttggtt agtcctagaa ccaatcaact
     2461 tatgtttatc ggcttggcag attttatgtt tgtcatttgt ttgtatagag gtatttcaga
     2521 aacagaattc tatcaacaac taatcgctta tataggtgta ttctctgctt gtttatcacg
     2581 cttctgctca tgtggggctt gaagtattat aaaaagtagc tttctatcct tttctgacag
     2641 gatatttgag tagaaggctc tattaaattg ttagtgaaat aaatgaatgg aggtatttaa
     2701 tatgaaatac agattatttt ttgttatttt cttgagtagt gtgttggata ttcttttagg
     2761 gacattttta caaatctcta tcgtatctat tgggtggctt gttctttaca gtggtttgtt
     2821 tgaagcagga gttttccttc ttgctaataa aggggtggcg gtaaaaatca aggaagtaga
     2881 tattcgaaat cgctttaaat ttatttttgg aaaaacctta tggtttcaaa ttcttttgct
     2941 catctttttg ataatcaaac tttatcttgg tttggatgcg aggttgattt tattctatgg
     3001 acatattttc attgtcttta atgccttaat gtatctatta tctagtagtc aggttagcct
     3061 taaaaaaaac aaactgtctt cttaatctta cagcagtaga gcctgacaag gtgaggtcat
     3121 agtagggagg atttctatga aaaagtatca acttctattc aaaataagtg cagttttctc
     3181 ttacttattt ttcgtatttg gtctttctca gatgacgctt attattcaaa attattggca
     3241 attttcttcc cagattggca atttcgtctg gattcaaaat ttcttgagtt tgctatttag
     3301 cggagtcatg atttggattc tggttaagac aggtcatggt tatctctttc acattccaag
     3361 aaaaaaatgg ctttggtatt cgattttgac agtattagtg gtagtgctcc agatctcttt
     3421 taacgttcag acagctaaac atgttcagtc aactgctgaa ggttgggctg tattgatcgg
     3481 ttatagtggg accaactttg ctgagctagg tatctatata actttgttct ttctgactcc
     3541 acttatggaa gagctaatct atagaggatt actgcaacac gcctttttta agcattcgag
     3601 atttggcctt gatttgcttc ttccgtcaat tttatttgct cttcctcatt tttcaagcct
     3661 gcctagtttg ttagatatct tcatctttgc aacatctggc atcatctttg ctagtttgac
     3721 ccgctatacc aagagcattt atccttccta tgcggtgcat gtgatcaata atattttcgc
     3781 aacattacca tttttgctga cttttttaca tagggtcttg gggtaaaaaa acaaaaggct
     3841 tgcttttcag ccatagagga gattatcatg tataaacact tatttttcct agattccaaa
     3901 actttagatc ggttgacacc ctatattcta gtcttggctt ctgacaccat tgcttttaat
     3961 gtttttgtgc taacctttgt atctgcggtg gtttttaatt tcctaaattc catgctagct
     4021 ttaatggcta tattcatagg ggctggctat gtggtcggat tttggttact aatactcaat
     4081 gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgt acttgagtac ggcaaggcga
     4141 cgttgacgtg gtttgaattt gattttcgaa gagtataaaa tggtttgttt tggaaaggct
     4201 agaactaaag aatgacgcgt aggaagtctg tttggtgagg aggatagttt tatggagttt
     4261 tttgataaat ttcatgcctt gtgttttgga tttttagtac taataattgt cattacagtt
     4321 ccttatacga ttaaccatgg gggttttttt caaaatgaat ctgcattgat tcttgtaagt
     4381 cttcttgtaa cctcgctgag tgttgcttat gctagaaagt ttgaaatgat ttcttttggg
     4441 atgttaagca agaaacaact tttgcttttc attgcaatct ttcttctaag tgtacttgag
     4501 acgctggttt atattcattt cttcgctgtt tcttctggct caggggtcca acacttggcg
     4561 gaagtcagca gaggaatttc cctgtctttg attttgacta cctcagtttt tggccccatc
     4621 caggaggaac tcattttcag aggacttctt caaggtgcgg tttttgacaa ttcttggtta
     4681 gggcttgtgc taacttcctc tctcttttct ttcatgcatg gaccttctaa tgtcccttcg
     4741 tttatttttt atctacttgg gggtttgttg ctgggctttg cttataaaaa gagtcaaaac
     4801 ctatgggttt ctactctagt ccacatgttt tacaacagtt ggccactcct atattattta
     4861 taaaaattat gaaaaggtaa gcagaagatg gtgcttacct ttttcaagct ataatgatac
     4921 ccaagccaat ccagaggctt ttctttgaga atcgggttag agtggttgac gaataggcca
     4981 aaaactagta gaatagtaag gaaactttat acggaggaaa gaaatggatt tgggtgataa
     5041 tgagctaaca ctgactccca tacctgggaa aagtggcaag gcttatatgg gtagctatcc
     5101 tgacgggaag cgcatctttg taaaaatgaa cacctctcca atcctacctg gtctagctag
     5161 agaacaaatt gctccacaat tattatggag tcgtcgtttg gcagatgggc gtgatatgtg
     5221 tgctcaagaa tggttgacag gcaagatatt gaccccctat gatatgaatc gtaagcaaat
     5281 cgtcaatatt ttaacccgtc ttcatcgctc acgtccgttg atgacacaat tgagtcgttt
     5341 gggctatgcc atggaaacac ctgtagattt actccagtct tggcaggaaa cggctccaga
     5401 tgctttgcgt aaaaatcatt ttatcagtga agtgatggct gatttacgtc agactattcc
     5461 aggatttaga gaggaccatg cgaccattgt ccatggagat gtacgacata gtaattggat
     5521 tgagacagat agtggcttga tttatttagt agattgggat tcggttcgct tgaccgatcg
     5581 catgtttgat gtggcccata tgctctgcca ttatatttca gaacatcagt ggaaggaatg
     5641 gttgacctac tacggttaca agtacaatca aacggtatta agtaaattgt attggtatgg
     5701 tcaattgtct tatttgagtc agatttccaa gtattatatg aaccaagatt tagaaaatgt
     5761 caatcgggag attcatggtt tgcgtcattt ccgagacaag tatggaaaga gaagatgaga
     5821 gttagaaatc gtaaaggggc aacagaatta ctagaggcaa atccccagta tgtggtcctc
     5881 aatcccttgg aagccaaggc aaaatggcgg gacttgtttg gcaatgataa tcccattcat
     5941 gtggaagttg gaagtggaaa gggtgccttt gtttcaggta tggccaagca aaaccctgac
     6001 atcaactata tcgggattga tattcaaaag tctgttttga gctacgcttt ggacaaggtg
     6061 cttgaagttg gagtgcctaa catcaagctc ttgtgggtag atggttctga cttaactgac
     6121 tattttgaag acggtgagat tgatcgcttg tatctgaact tttcagatcc atggccgaaa
     6181 aaacgccatg aaaagcgtcg tttgacctac aagaccttct tggatacctt caaacgtatc
     6241 ttgcctgaaa atggagaaat tcatttcaag acggataacc gtggcttgtt tgagtacagt
     6301 ttagtgagct tttctcaata tggcatgaaa ctcaatggtg tctggttaga tttgcatgcc
     6361 agtgattttg aaggcaatgt catgacagaa tacgagcaaa aattctcaaa caaggggcaa
     6421 gttatctacc gagttgaggc agaattttaa gagatagcct aaaattaggc tgtacaagtg
     6481 cttttgcttt acataagttg gcaaacgtgc tatactgata gtaagaatat gaaaagtgag
     6541 gcggggaaat atcttcgcct cttgcttatg aggaggtgga cgcaatcgca acaatcgtag
     6601 aattagtcag agaagttgta gaacctgtca tagaagctcc ttttgaactc gtggatatcg
     6661 agtatggaaa gattggcagt gacatgattc tcagtatttt tgtagataaa cccgaaggaa
     6721 ttaccttgaa cgacacggca gacttgacag aaattatcag tcctgtccta gacaccatca
     6781 agccagatcc cttcccagaa caatatttcc tagaaattac cagtccaggt ttggaacgcc
     6841 ctttgaaaac caaggatgcc gtcgctggag cggttggaaa atacatccat gtcgggctct
     6901 accaagccat cgataagcaa aaggtctttg aaggaacctt gttggccttc gaagaggacg
     6961 ggttgactat ggaatatatg gacaagacgc gtaagaaaac cgtccaaatt ccatacagtt
     7021 tagtatcaaa agcacgttta gcagttaaat tatagaaaaa gaaaggatag cttttgagga
     7081 ttcaaaagtg aagaaaacat gagtaaagaa atgctagagg ccttccgcat tttggaagaa
     7141 gacaagggaa tcaaaaaaga agatatcatc gacgcagtag tagagtcgct tcgttccgct
     7201 tatcgcagac gctatggtca gtcagacagc gtagctattg acttcaacga aaaaacaggt
     7261 gactttacag tttatactgt ccgtgaagtt gttgatgaag tatttgatag ccgtttggaa
     7321 atcagcttga aagatgctct tgccattaat tcagcttatg aacttggaga caaaatcaag
     7381 tttgaagaag caccagctga gtttggtcgt gtagcagccc agtctgccaa acaaaccatc
     7441 atggaaaaaa tgcgcaagca aacacgtgcc atcacttaca atacttacaa agaacatgag
     7501 caagaaatca tgtctggtac agtagaacgc tttgacaacc gctttatcta tgtcaacctt
     7561 ggtagcatcg aagcccaatt gtcaaaacaa gaccaaattc ctggagaagt ttttgcttct
     7621 catgatcgta tcgaagttta tgtttacaag gttgaagaca accctcgtgg tgtgaacgtc
     7681 tttgttagcc gtagtcatcc agaaatgatc aaacgtttaa tggagcaaga aattccagaa
     7741 gtttatgatg gaactgttga aatcatgagc gtggctcgtg aagcaggtga ccgtacgaag
     7801 gttgctgttc gtagccacaa tccaaacgtg gatgctatcg gtacaatcgt tggacgtggt
     7861 ggtgctaata tcaagaagat tactagcaaa ttccacccag ctcgttacga tgctaaaaat
     7921 gaccgcatgg taccaatcga agaaaatatc gatgttatcg agtgggtagc agatccagct
     7981 gaatttatct acaatgccat cgctcctgct gaggttgacc aagttatctt tgatgaaaac
     8041 gacagcaaac gtgccttggt ggttgttcca gataacaagc tttctcttgc cattggtcgt
     8101 cgtggacaaa acgtgcgctt ggcggctcac ttgactggtt accgtatcga tatcaagtct
     8161 gctagcgaat ttgaagccat ggaagacgct gcttcagtag agttggaagt agaaaacgat
     8221 actgtagaag aataaaagct gctagaggag ggaaagatga aaacaagaaa aatccctttg
     8281 cgcaagtctg ttgtgtctaa cgaagtgatt gataagcgtg atttgctccg cattgtcaag
     8341 aacaaggaag gacaagtctt tattgatcct acgggcaagg ccaatggccg cggcgcttat
     8401 atcaaactag acaatgcaga agccctagag gcgaaaaaga agaaggtctt taaccgcagc
     8461 tttagcatgg aagtggaaga aagcttttat gacgagttga tcgcttatgt ggatcacaaa
     8521 gtgaaaagaa gagagttggg acttgaataa gcaaaagata agtaatctct tggggcttgc
     8581 tcagcgagca gggcgcatca tatcgggtga agaattggtg gtcaaggcca ttcaagacgg
     8641 caaggccaag ttggtctttc tagctcatga tgctggaccc aatctgacca agaagattca
     8701 agataaaagt cattattatc aagtagaaat tgtaaccgtg ttttcaacac tggaattaag
     8761 catagcagtc gggaaatcga gaaaggtttt ggctgtaaca gatgctggat ttacaaagaa
     8821 aatgaggtct cttatggaat agaagaggag gacatgattt gtctaagaaa agattgtacg
     8881 aaatcgcaaa agaacttgga aaagaaagta aagaagttgt agcgcgtgca aaagagttgg
     8941 gcttggatgt gaaaagccac tcatcaagtg tggaagaagc tgtcgctgca aaaattgctg
     9001 ccagctttaa gcctgcagct gctccgaaag tagaagcaaa acctgcagca ccaaaagtaa
     9061 gtgcagaaaa gaaagccgaa aaatctgagc cagctaaacc agctgtagct aaggaagagg
     9121 caaaaccggc tgagccagtt gctccgaaaa cagaaaaagt agcagtgaaa ccgcaaagtc
     9181 gtaatttcaa ggctgagcgt gaagcccgtg ctaaagagca ggcagaacga cgcaagcaaa
     9241 ataagggcaa taaccgtgac caacaacaaa acggaaaccg tcagaaaaac gacggccgta
     9301 atggtggaaa acaaggtcaa agcaaccgcg acaatcgtcg ctttaatgac caagctaaga
     9361 agcagcaagg tcagcaaaaa cgtagaaatg agcgccgtca gcaagaggat aaacgttcaa
     9421 atcaagcggc tccacgtatt gactttaaag cccgtgcagc agccctaaaa gcagagcaaa
     9481 atgcagagta cgctcgttca agtgaggaac gcttcaagca gtatcaggct gctaaagaag
     9541 ccttggctca agctaacaaa cgcaaggaac cagaggaaat ctttgaagaa gcggctaagt
     9601 tagctgaaca agcacagcaa gttcaagcag tggttgaagt cgtccctgag aaaaaagaac
     9661 ctgcagtgga tacacgtcgt aaaaaacaag ctcgaccaga caaaaatcgt gacgattatg
     9721 atcatgaaga agatggtcct agaaaacaac aaaagaatcg aagtagtcaa aatcaagtga
     9781 gaaatcaaaa gaatagtaac tggaataaca acaaaaagaa caaaaaaggc aataacaaga
     9841 acaaccgtaa tcagactcca aaacctgtta cggagcgtaa attccatgaa ttgccaacag
     9901 aatttgaata tacagatggt atgaccgttg cggaaatcgc aaaacgtatc aaacgtgaac
     9961 cagctgaaat tgttaagaaa cttttcatga tgggtgtcat ggccacacaa aaccaatcct
    10021 tggatgggga aacaattgaa ctcctcatgg tggattacgg tatcgaagcc aaacaaaagg
    10081 ttgaagtgga taatgctgac atcgaacgtt tctttgtcga agatggttat ctcaatgaag
    10141 atgaattggt tgagcgtcca ccagttgtta ctatcatggg acacgttgac cacggtaaaa
    10201 caaccctttt ggatactctt cgtaactcac gtgttgcgac aggtgaagca ggtggtatta
    10261 ctcagcatat cggtgcctac caaatcgtgg aaaatggtaa gaagattacc ttccttgata
    10321 caccaggaca cgcggccttt acatcaatgc gtgcgcgtgg tgcttctgtt accgatatta
    10381 cgatcttggt cgtagcggca gatgacgggg ttatgcctca gactattgaa gccatcaacc
    10441 actcaaaagc agctaacgtt ccaatcatcg tagccattaa caagattgat aaaccaggtg
    10501 ctaacccaga acgcgttatc ggtgaattgg cagagcatgg tgtgatgtca accgcttggg
    10561 gtggagattc tgaatttgtt gaaatctcag ctaaattcaa ccaaaatatc gaagaattgt
    10621 tggaaacagt ccttcttgta gctgaaatcc aagaactcaa ggcagaccca acagtgcgtg
    10681 caatcggtac ggttatcgaa gcgcgcttgg ataaaggaaa aggtgcggtc gcaacccttc
    10741 ttgtacaaca aggtaccttg aatgttcaag atccaatcgt tgtcggaaat accttcggtc
    10801 gtgtccgtgc tatgaccaac gaccttggtc gtcgtgttaa agttgctgga ccatcaacac
    10861 cagtctctat cacaggtttg aacgaagcac cgatggcggg tgaccacttt gccgtttacg
    10921 aggatgaaaa atctgcgcgt gcagcaggtg aagagcgtgc caaacgtgcc ctcatgaaac
    10981 aacgtcaagc tacccaacgt gttagccttg aaaacctctt tgataccctt aaagctgggg
    11041 aactcaaatc tgttaatgtt atcatcaagg ctgatgtaca aggttctgtt gaagcccttt
    11101 ctgcctcact tcaaaagatt gacgtggaag gtgtcaaagt gactatcgtc cactcagcgg
    11161 tcggtgctat caacgaatca gacgtgaccc ttgccgaagc ttcaaatgcc tttatcgttg
    11221 gtttcaacgt acgccctaca ccacaagctc gtcaacaagc agaagctgac gatgtggaaa
    11281 tccgtcttca cagcattatc tacaaggtta tcgaagagat ggaagaagct atgaaaggga
    11341 tgcttgatcc agaatttgaa gaaaaagtta ttggtgaagc ggttatccgt gaaaccttca
    11401 aggtgtctaa agtgggaact atcggtggat ttatggttat caacggtaag gttgcccgtg
    11461 actctaaagt ccgtgttatc cgtgatggtg tcgttatcta tgatggcgaa ctcgcaagct
    11521 tgaaacacta caaagacgac gtgaaagaag tgacaaacgg tcgtgaaggt ggattgatga
    11581 tcgacggcta caatgatatt aagatggatg atgtgattga ggcgtatgtc atggaagaaa
    11641 tcaagagata agattttttg ctcctttctt aggtggtgag ggacgcaagc aaaccgatgg
    11701 tttcattgct tatttttgag cctagggtct caaaaatccc ctgtgatggg actgataaat
    11761 cagttccatc actttcacca cggcgaaaga agcagatgac ttcaaattga acttcgtttc
    11821 aatttaaact gaaaatcaag aagtttaaaa tagctaggtc tgctggccta gcttttggtt
    11881 caaagtagag aaaggaatat catggcaaat catttccgta cagatcgtgt gggcatggaa
    11941 atcaagcgtg aagtcaatga gattttgcaa aagaaagtcc gtgatccacg tgtccaaggt
    12001 gtgaccatca cagatgttca gatgctgggt gacttgtctg ttgccaaggt ttattacacc
    12061 attttgagta accttgcttc ggataaccaa aaagcccaaa tcgggcttga aaaagcaact
    12121 ggtaccatca aacgtgaact tggtcgcaat ttgaaattgt acaaaatccc agatttgacc
    12181 ttcgtcaaag acgagtccat cgagtatgga aacaagattg acgagatgct acgcaatctg
    12241 gataagaact aaagaagagg ggttgcccct cttttttggt ggaggaaaat aggttgaatt
    12301 tgaaatggaa aaatattctt ttaaaatata ttgaaactag aatagtacgc ctctacttct
    12361 aaaacattgt tagaaatcga tttgactgtc ctgatcgatt tgtcctgttc ttgtttcatt
    12421 ttactataaa aaaggggttc tgtatttttt aatgttatct aattagaaaa tgcttttttt
    12481 gtaggaaata taatatgata aggtgtaaaa aagaaataag gagtttgtat atggctgaac
    12541 aagacttagc tatgcaagta ttgcaacaag tggtgaaact acctgttgtt aaggttgatc
    12601 gttcgaaatt tttagtggat aagttttcca aagaattgga tccaaaagat attcctacct
    12661 tattggaaca aggtacaacg actcttctat ctcaagaaat attagatcgt gtagctaatg
    12721 cttgtattcg ggacaatgta ttattagcga gtgggacttc tgttttggca ggattagctg
    12781 gagggcttgc tatggcaatt accattccag ctgatgtggc tcaattttat gctttctctc
    12841 tgaaattggc tcaagaatta ggttatattt atggttatga ggatctttgg gcttcacgcg
    12901 aggagttgag tgaagatgct caaaataccc tcttgcttta tctaggcgta atgttagggg
    12961 tgaatggaac cgctgctttg ctatgtgctg gtggtataac aattgccaaa caggtaatga
    13021 aaacagtgcc taataaagct ttaacaaaga cgctttggta ccctattttg aaaaaagtct
    13081 taaaaatatt tggtgtgaat cttaccaagg gagggctggc caaaggaata gggaaattta
    13141 ttcctatctt gggtggtatc attgcaggtg gtttaacctt tgcaactatg aaaccaatgg
    13201 gggaaagctt gcagaaagaa ttatccaagc tagtcaacta tagtgaagtt caatatcaag
    13261 aagatgttga aacaatccga aaagaggctg aaatcattaa aggagagtaa tatgaatcct
    13321 atcaaagctt ttgataaaat ttatggtaat tactttttga ccgtgcaagg tgtaaaagtg
    13381 atgaaaacga taaagaaagc tgaccatgtc gttgttggtc tgggaaaact ttttattgca
    13441 gataagctaa tggatacggc tcggtggctc attaggccag aggagagaga atgaaatttt
    13501 ttttggtctt cttgctattc tttttatcaa accgattatt gggattgtga aattcttttg
    13561 gatgatcatt tcctttgcag ttcaattgct gttttacaag atattattta agatattgga
    13621 ttggctcttt aaacttatct agatggtaat ccaagtcgca gagagctagc aggaactcca
    13681 ctgctagttt tttaatctct ctccatatgg tataatataa gcagtaaaat cattttatac
    13741 tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc agtatatatg ttactgactt
    13801 cgtcagttct atccacaacc tcaaaacggt gttttgagct gacttcgtca gttctatcca
    13861 caacctcaaa acggtgtttt gagctgactt cgtcagttct atccacaacc tcaaaacggt
    13921 gttttgagct gacttcgtca gttctatcta caacctcaaa acactgtttt gagcaacctg
    13981 cggctagctt tctagtttgc tctttgattt tcattgagta ttagaacata taatggaggt
    14041 cgtcatggac aatatcatcg atgtgtcaat tcctgttgca gaagtggtgg acaagcatcc
    14101 agaagtcttg gaaattctag tggagctggg ttttaaaccc cttgccaatc ccttgatgcg
    14161 caatacagtt ggtcgtaaag tatcacttaa acaaggttct aagctagcag gaactcctat
    14221 ggacaagatt gtacgcacac tggaagcgaa tggctacgaa gtgattggat tagactaatg
    14281 gcagatgaac ggattcatgt cctacgggat attttattag aattgcataa tggcgcctct
    14341 cctgagtcgg ttcaggagcg ttttgatgcg acctttgcgg gtgtctcagc cattgagatt
    14401 tcccttatgg agcacgagct gatgaactca gactcaggtg tcacctttga agatgttatg
    14461 gaactctgtg atgtccatgc caatcttttt aaaaatgcta tcaaaggtgt cgaagtttca
    14521 gatactgagc atccaggtca cccagttcgt gtcttcaaag aagaaaatct ggctctccgt
    14581 gcggccttga ttcgcattcg tagattgtta gatacctatg agtctatgga agacgaggaa
    14641 atgctggcgg agatgcgtaa gggtttggtg cgtcagatgg gacttgtggg tcaatttgac
    14701 atccattacc aacgtaagga agaactcttc tttcctatca tggagcgcta tggacacgat
    14761 tcacctccca aagttatgtg gggagtggat gatcagatta gggaactctt tcaaacagct
    14821 ctaacgatag ccaagtcact accagaagtg tcaattagca gtgtaaagga agcttttgaa
    14881 gcttttgcga cagagtttga aagtatgatt ttcaaggaag agtccatcct cctcatgatt
    14941 ctccttgagt cttttactca ggatgactgg cttcagattg cggaggagag cgatgcctat
    15001 ggctatgcca tcatccgtcc gtcagagaaa tgggtgccag aacgacagag ctttattgag
    15061 gaaaagattg cagaggagcc tgtacagcta gatacggcag aaggtcaagt tcaacaagtc
    15121 atagatacgc cagaaggcca ttttaccatt acctttaccc ctaaggaaaa ggaagctgtg
    15181 ctggaccgcc atagtcaaca ggcttttggt aatggctatc tttcagtcga gcaggccaat
    15241 ctcatcctca atcacctccc tatggagatt acctttgtca ataaagatga tattttccag
    15301 tattacaatg acaatacgcc agctgatgag atgattttca aacggacgcc gtctcaagtc
    15361 gggcgcaatg tcgaactctg ccatccgcct aagtacttgg acaaggtcaa aactatcatg
    15421 aaggggcttc gtgaggggac caaggacaag tatgaaatgt ggttcaagtc tgagtcgcga
    15481 ggtaagtttg tccacatcac ctatgctgca gtacacgatg aagacggaga attccaagga
    15541 gtgttggagt atgttcagga tatccagccc taccgtgaga ttgatacgga ctattttcgt
    15601 ggattagaat aaggagaaaa aatgagttac gaacaagaat ttatgaagga atttgaagct
    15661 tgggtcaata cccaaatcat gattaacgac atggcgcaca aggaaagtca aaaagtttac
    15721 gaagaagacc aggacgagcg tgccaaagat gccatgattc gctacgagag tcgcttggat
    15781 gcttatcagt tcttgcttgg taagtttgaa aacttcaaag caggcaaggg attccatgat
    15841 ttgccagaag gcttgtttgg tgagcgaaat tattaaacga gaaagattct tgatttttca
    15901 ctaaaatctt gatagaatgt ttatgttaaa tccttgtcag agcagggatt ttttattgaa
    15961 aggattttat catgtcaaag aaactcaatc gtaaaaaaca attacgaaat ggcctccgtc
    16021 gcgcaggtgc cttttcaagt actgtgacta aggttgtaga tgagacaaaa aaagtcgtga
    16081 agcgtgcaga acagtcagca agcgcagctg gtaaggctgt ttctaaaaaa gttgaacaag
    16141 cagtagaagc taccaaagag caagctcaaa aagtagctaa ttctgtagaa gattttgcag
    16201 caaacttggg tggacttcca cttgatcgtg ccaagacttt ctatgatgaa ggaatcaagt
    16261 ctgcttcaga tttcaaaaac tggactgaaa aagaactcct tgccttgaaa ggaatcggcc
    16321 cagctaccat caagaaattg aaagaaaatg gcatcaagtt caagtaattt ttcttgagcc
    16381 ttgcatttcc gagaaaaact tgctacaata gagccattag aggtgttttg aatcccacat
    16441 tttacagaaa gtggcggcgc tgagaagtcc acaaatgtgt caaaactggt tgctaatgac
    16501 tgaaaaaatg aaataaaagt gtctttttgc tttaaagacg agagttgcgg gcaactgccc
    16561 gaaattgggt ggtaccgcgg ataaacacat tcgtccctgt catgtagatg gcagggcttt
    16621 tcttttacgt cttagtcaaa gggggttgtt atgaagcaat cttttaacac aagtaaacta
    16681 tattatggtt ttcctgtttt tattttagga tatcaagatt agaattttgg ctataacatc
    16741 acgacctgta gttcctctta tagtctagga gattgggttg tgattggagt cgttgcgaga
    16801 gagaatgccg cagagcagat caaacagtat caaaaattta ctgtgaatat ttctgatgaa
    16861 acttctatgc ttgcgatgga gcaggctggt tttatcagtc atcaggagaa attggaacgt
    16921 ttgggagtgc attatgaaat ttctgaacga actcagactc ctattttaga cgcctgtcca
    16981 cttgttttag attgtagggt agataggatt gttgaggaag acggtatttg ccacatcttt
    17041 gccaagattc ttgagcgact tgttgcccca gaactcctgg atgaaaaggg acattttaaa
    17101 aatcaactgt ttgccccaac ctatttcatg ggagatggat atcagcgcgt ttatcgctat
    17161 ctggataagc gtgtagatat gaagggcagt ttcatcaaaa aagcgaggaa gaaggatggc
    17221 aagaactgag ctgccagatc aaatcgaaac agaacgtctc gttttacgag tccgtactgt
    17281 ggcggatgct gaggatatct ttgactatgc tagtttgcca gaggtcgcct atccagcagg
    17341 ttttcctcca gtcaagacct tggaagatga gatttattat ctggagcaca ttcttccgga
    17401 gcgtaatcaa aaggaaaatc tcccagcagg ctacgggatt gtcgtcaaag gaacggataa
    17461 gatcgttggc tctgtcgatt tcaaccatcg ccatgaagat gatgtgctgg aaatcggcta
    17521 taccttacac ccagactatt gggggcgagg ttatgtgcca gaagctgcgc gtgccttgat
    17581 tgacttagcc tttaaagatt tgggtcttca caagattgaa ctaacttgct ttggatataa
    17641 ccttcaaagt aaacgagtcg cggaaaagct tggctttacc ctcgaagctc gcataagaga
    17701 ccgcaaagat gctcaaggca actgctgtga cagtctgata tatggcttgc tgaagagcga
    17761 gtgggaggaa taagatgagc gatgtaaaag aggaagtaag ctctctatct gagaagcagt
    17821 tacgccaaat tgatgttgag tatgctgaat taaatgatag tgatattatc gagcgattag
    17881 cttatttaga aattaacaac aatgaaaaac gtattgtcat ctctgatatt gaaccaacca
    17941 aggaaataat gtcagtctcg gaccaaattt ttgagattca aaagaatttt caaaaaatca
    18001 agaatatgtt cgaattgttt atttcagatg tctcggattt tttaagtatt aaaaataaac
    18061 ttgagtcaaa ggaattagaa attgaagagg cagatgtaaa tcgtttcatg attcatttat
    18121 tatccagtgg aaaattgttt gtcgatttta acgaaaacca aattaaacaa aaatattcca
    18181 aagatagtga ggagtttgat tgtatacatg gttttgcaag ctatcagtat gataccaatt
    18241 ttgcttatcg attttgccat tctttgagaa attattcgca acatactgac ttaccaataa
    18301 atgaggtaaa agctgttagc ccagatgatg agactgttat aatagatttc tatattgatt
    18361 tagattatct tttaaattcc aactttaaat ggaaaaaatt gaaaggggag ttgataaaac
    18421 taaaccaaga aacatctaag attgacgcta tagctctagt gaaagaatac tttaatgc
//
LOCUS       DAVLCS010000037        18221 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLCS010000037 DAVLCS010000000
VERSION     DAVLCS010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18221
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.037"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            693..1265
                     /locus_tag="VXC78_001594"
     CDS             693..1265
                     /locus_tag="VXC78_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583641.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALEGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(2310..4568)
                     /gene="glgP"
                     /locus_tag="VXC78_001595"
     CDS             complement(2310..4568)
                     /gene="glgP"
                     /locus_tag="VXC78_001595"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV0583642.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(4594..6111)
                     /gene="malQ"
                     /locus_tag="VXC78_001596"
     CDS             complement(4594..6111)
                     /gene="malQ"
                     /locus_tag="VXC78_001596"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV0583643.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            6661..7932
                     /locus_tag="VXC78_001597"
     CDS             6661..7932
                     /locus_tag="VXC78_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0583644.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            8043..9335
                     /locus_tag="VXC78_001598"
     CDS             8043..9335
                     /locus_tag="VXC78_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0583645.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            9337..10179
                     /locus_tag="VXC78_001599"
     CDS             9337..10179
                     /locus_tag="VXC78_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0583646.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            10432..11232
                     /locus_tag="VXC78_001600"
     CDS             10432..11232
                     /locus_tag="VXC78_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV0583647.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNIYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDSNYHK"
     gene            11242..12228
                     /locus_tag="VXC78_001601"
     CDS             11242..12228
                     /locus_tag="VXC78_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0583648.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            12364..12444
                     /locus_tag="VXC78_001602"
                     /pseudo
     CDS             12364..12444
                     /locus_tag="VXC78_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(12565..13506)
                     /locus_tag="VXC78_001603"
     CDS             complement(12565..13506)
                     /locus_tag="VXC78_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0583649.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(13484..15247)
                     /gene="aspS"
                     /locus_tag="VXC78_001604"
     CDS             complement(13484..15247)
                     /gene="aspS"
                     /locus_tag="VXC78_001604"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV0583650.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            complement(15528..15608)
                     /locus_tag="VXC78_001605"
                     /pseudo
     CDS             complement(15528..15608)
                     /locus_tag="VXC78_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(15644..15874)
                     /locus_tag="VXC78_001606"
     CDS             complement(15644..15874)
                     /locus_tag="VXC78_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583651.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(15892..16533)
                     /locus_tag="VXC78_001607"
     CDS             complement(15892..16533)
                     /locus_tag="VXC78_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0583652.1"
                     /translation="MKLLKNLGWILLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(16545..17279)
                     /locus_tag="VXC78_001608"
     CDS             complement(16545..17279)
                     /locus_tag="VXC78_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV0583653.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(17282..17479)
                     /locus_tag="VXC78_001609"
     CDS             complement(17282..17479)
                     /locus_tag="VXC78_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583654.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(17479..17685)
                     /locus_tag="VXC78_001610"
     CDS             complement(17479..17685)
                     /locus_tag="VXC78_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0583655.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(17695..18009)
                     /locus_tag="VXC78_001611"
     CDS             complement(17695..18009)
                     /locus_tag="VXC78_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583656.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
BASE COUNT         5585 a         3868 c         3341 g         5427 t
ORIGIN      
        1 atctgcaacc tcaaagctgt actttgagca acctacggct agtttactct ttgattttca
       61 ttgagtataa actagacttc ccaaaggtat aaaacttacc gaaaatcttc aatattacaa
      121 aaacgcataa gaacaggtac acaaacctta atcttatgcg ttttgttata gtttccatac
      181 acattaaggg gaaatagttg aaatcagttc tcttaataac cattgaatac catatactac
      241 atttacccca aatatgatat aggccgtata aatcaagtat ttcgatttct cccgtctcaa
      301 agaatagatc ttgtacaaaa tagataaatt taaaataata aataatagag acaaaatctt
      361 cctccaaaat caatattaaa agtagccagt caatcatagt tctaatcttt attttcgatt
      421 cgaaattaca aacttatcaa tgaacaataa gtgatataag gccagtacca gaccccaaac
      481 gctaccacga aaagagaatt cttgatgatt gagagtaaac aaatcatggt taccaatata
      541 gaggcaggtc aaaataacaa ataaaatcca aaataaatcc gtccatttat attttgaaaa
      601 atattttttt aacataatag catatttttc ttgactataa taacagtata taataaaatg
      661 taagcagata caaataaaaa ggagaaaagc tcatgaacaa attaatgaaa tttatttcgg
      721 tttttttgac gtcaattgtg ttaattgtat cagcgattcc aagtgtttca gctgtatacg
      781 cttctgaaca agtatcgcaa attgaaacaa atatggaact tcaacctgtc acttctctaa
      841 cagaagaaca aatcaataca cttgcaaacg aaatccaatc ttttcatcca gacgtctcac
      901 aacaatggat caaagaagta attaaccgac aattacaagg cgattataca atcccaccta
      961 catactctcc atttagagca gcttggcaag gtattacagt taatcaaatg ggtgctctat
     1021 tagatactgc aatagcttta gcattagaag gaactactgc aggccttgca aatctaatta
     1081 aagtaaaagg aaaacatgca gcaaaaagtg ctattcgttc agcaatttct agatatctag
     1141 gtagttggtt tgtaaatgat gttgctttag aattcgctat gaatttatta tcaccaggga
     1201 cttatttagc acaattatgg gataaaaatg atgccattcc taacaacgga aggattaact
     1261 tttaatcatg agatatacaa taaaattaat tgggtataac gtattttcgt tgtttatatt
     1321 ctttatctta tcaatgttgt ttaaagttcc ctttaggtgg tggatcagca ttgcaatgac
     1381 gacttcgtcg tacattgtat ataattactt aaagaaaaag agagaaaagg aatgatctta
     1441 taccagatca ttccttttct gctttctgta aatccctcgg agtgtgtttg gcgctttgat
     1501 acgaagtgtc aaagctgtat aaacgttact atttccaaaa aagtaacaga aaattcctgc
     1561 tttgtaggac tgctttgggt gagtaataga catgtcgact caccctatct cctgatggcg
     1621 aaaagaattt agcaatggtg caagttgttc tgaactcgag aaaaaacatg ccgaaatcga
     1681 agaaaagcgt gcagaacttg aagcgaagaa gcaagaaatg ttgaatcgct tggataaata
     1741 gaatttagaa aacagaaaaa actaaaaaaa atgtagggtt tatttcccta cattcttaaa
     1801 ataacttagt acataaatga caatgctgcc actgccgtca atattgcaaa aactattttc
     1861 caaatttttt tattttttcc aaaaatctta tcaggtaaca agcttattac aagaaaggta
     1921 ataaacaaca ccaatttaag tgtgtatatc ataaaaacac cttctttcct acaattatat
     1981 tataatactt tatgtaagcg aatacaagag atgtgaggta accaactacg aaaaaatata
     2041 aggctgaaga cagtaaaaac cagcatttaa agccttcact gtatctagga tttccctatt
     2101 tttagacaag attgacccaa atccacagca tttaaaaaag cgaatttcaa tcgaaactcg
     2161 cttttttaca agatgtatta gtataaattt gtatcttata ctcaatgaaa atcaaagagc
     2221 aaactaggaa gctagccgca ggttgctcaa agcaccgctt tgaggttgca gataaagctg
     2281 acgtggtttg aagagatttt cgaagagtat tagttcaagt gccagatgtc ttcgttatac
     2341 tgagcgattg tacggtcaga tgagaagaat cctgctttag aaatgttaac gatgacttta
     2401 tccaaccatg cgtcacggtc ttcgtagtca gcaagcattt gctctttgac tttgatgtag
     2461 tcttccaaat caagaagagt catgaaccag tctttgttga tcaattcatt gtaaagacgt
     2521 tccaagcgct ctttgtttcc agctgcaaga actgcatcac taacgatgaa gtcaaccaat
     2581 ggtttgatag cttcacgagc gtagaattcg cttgatttgt aagctgcttt tgcgtaaagg
     2641 tcgataacag tttctgaatc ttcaccgaag atgtagatgt tttcttctcc aaccaactca
     2701 gcgatttcca cgttagcacc gtccatagta ccaagtgtca aagctccgtt caacatgaat
     2761 ttcatgttac cagtacctga agcttcttta gaagcaagtg agatttgttc tgagatatca
     2821 catgctggga taaggaagct tgctgcagta acgttgtagt tttcaaccat aactacttgc
     2881 aagtgtggag ctactgctgg atcgttagca ataacttctg acatgcaaag gatcaagtga
     2941 atgatatctt gagcgattgt gtaggctgga gctgctttac caccaaagaa gattgtgatt
     3001 ggacgagcag ggatgttacc agctttgatg tcaaggtatt tgtggattac gtacaaagcg
     3061 ttcatttgtt ggcgtttgta ctcgtgaaga cgtttgattt ggatatcaaa gatagaattt
     3121 gaattgattt ccacaccttg gtgttctttc aagtgacgag ccaatttacg tttgttgtga
     3181 gccttgatgc tttccaattt ttctttgaca gctgctttgt cttcataaga caaaagtttt
     3241 tcaagctcat ctgcttcatg gtgccaacca tctccaagaa tctcatccaa gtagtgagac
     3301 aatcttgggt tagcatgcat aagccaacga cggaaagtga taccgtttgt tttgttgttg
     3361 aacttttctg ggtaaaggtc gtagaaggct ttcaactcag aatttttcaa gatttcagta
     3421 tggagtgctg caaccccgtt aacactgtat ccgtagtgga tatccatgtg agccatgtga
     3481 acacgtccgc tctcatcgat gatttgaaca gctggatctt tgtactctgc cttcacacga
     3541 cggtccaatt cttcgatgat tggtaccaag tgaggaacca cttcttgcaa gaattcaaga
     3601 ggccattttt caagcgcctc agcaaggatt gtgtggttag tgtaggcagt catgctacga
     3661 acaattgaga ttgcttcgtc aagctcgata ccacgtgcag tcaaaagacg aatcaattca
     3721 ggaatcacca ttgatgggtg agtatcgttg atttggacaa ctgcgtagtc agcaaggtca
     3781 tgcaagttgc ttcctttttc gattgcttcg tcgatgatca attgcgcacc gtttgaaacc
     3841 atgaagtatt gttggaagat acggagcaat tcaccttgac ggtcactatc atctgggtaa
     3901 aggaagagag ttaagttgcg agcgatatct gtcttgtcaa agttgatacc atctttaata
     3961 atagaagaat caactgaatc caagtcaaac aaacgcaagc ggtttttagt cgctgtttca
     4021 taaccagtaa catcaatatc gtaaagagtt gatgtcaaag taaagtctgc aaatggtact
     4081 tggtagctac ggcttgagcg aaccaaccag ttttgctctg tcaaccatgc atttggaatt
     4141 gtttcttgtt ggttgttttt aagaacttgt tggaaaagac caaagtggta gttaagacca
     4201 acaccgtcac cattcaaacc aagagtagca attgagtcga taaagcaggc agccaaacgt
     4261 cccaaaccac cattaccaag agatggttcc aattcaactt cttcaacttc gattaagtct
     4321 ttacctgcag ctgcaagttc ttttttaaca tcgtcgtaaa gaccaaggtt aatcaagttg
     4381 tttgacaaga gtttaccaat caagaactca gctgagatgt agtaaacttt tttcttacca
     4441 gtgttgactg gtttttggct gcttgcaagc ttgctgtagt taagaagagc aaggtaaagc
     4501 tcttcattgc tacattctgc aatggtttta ttgtaacgat tttgtacaaa ttcttgtagt
     4561 gataacatgt ttagttgtct cctgattatt gtcttatttc tttaaatcta ccaaattttc
     4621 attaattcgg cgataaattg ttgtcaagtc aagcaaacct tcctcgacag ctggtgtcaa
     4681 ttgatcttca gtcatacgcc aagaccagtt tccaccaagg gtagatggga agttcatacg
     4741 agctgcctca tccaattcta gtaaatcttg catagttgca attgccataa agctaactga
     4801 tgaaaatact gtacgaagca tagcgtgtac cactgtttca tattctttac ggttcgtgta
     4861 acgagccatg tactcacgag tcgcatcatc aatctcgtta cggtaccaac caagaaccgt
     4921 attgttatcg tgtgttcctg tgtacataac tgagttagca ggtgccaagt gtgggctatc
     4981 aatgctttcg tcttctgggt tgaaggcaaa ttgaagaatc ttcattcctg ggaagccagt
     5041 acgttcacgc aattcgatca cttcatctgt catgaagcca aggtcttctg cgatgatgtt
     5101 tagctcacca agttcttcct taacggctgc aaaaagcttg tagcctggac ctttcaccca
     5161 ctcaccaggt gctgctgtat cggaaccagc agggatttcc cagtaagatt cgaagccacg
     5221 gaagtggtcg atacgaacga tatcgtagat tttgaagctt tcacgcaagc gttcaatcca
     5281 ccatttgtag ccgtctttgt ccattgcttc ccagtcatag attgggttac cccaaagctg
     5341 accagttaca gaaaactcat ctggtgggca tcctgcgata caagtagcct taccattgac
     5401 atctgttttg aagagatgtg gatttgccca catatcactt gaatcttccg ctacgtagat
     5461 tggcatgtcc ccaacgattt cgatgtggtt gtcgttagcg taagctttca atttcaacca
     5521 ttgttggaag aagaagtatt gagtcacacg gtggtaaacc aacttgtctg ccaattgctc
     5581 acgatagctt tcaagtgctg aagctttacg agcacgagca tctgcatctg gccattcagt
     5641 ccaagcaaga ttgtcaaaat actctttgat agccatatac tcagcaaaga gctcaagcca
     5701 tgattggttg tcttgagcaa atttctcaaa atctttaaca tctccgactt caaagaaacg
     5761 tttcaccgct ttttctaaaa gaggacgacg tgcatagtag attttagcat agtcaacttc
     5821 agacgcatcg ctaccaaagt caactccttc aaggtcactt gcttccaaca aaccttgctc
     5881 caccaagata tctaaatcga taaaatgagt gtttcctgcg aaggctgaga aagattggta
     5941 aggagaatcc ccgtaactag ttgctcctaa tggaaggatt tgccagtaac gttgttttgt
     6001 acggaccaag aaatcaacga agtcgtaagc actttgacca aatgatccga ttccgtaagc
     6061 tcctggaaga gaagagatgt gcatcaacac accactttga cgttttttca taatagcacc
     6121 tcgtgtgtta aaataatgga acgttgcgta ttttgcagac gcaaacgttt gcgttactta
     6181 taagtatact ccttttcaag cataattgca agcgttttta aaaaactttt ttgattattt
     6241 ttaaggagac taactcattt tagcaaagat aacttaaaac tatctaatcc taaagtttga
     6301 ctctcacgag acagtctaca aagtacaaaa cctccttagg gagcttgaat ttatatgcaa
     6361 caaagcacaa acgtctatag aaaatagata gggattagaa acagggaggt agcccctcct
     6421 gatttccctc tttagacaga ttccatatat ttttattaaa aatactgtat tcttatctat
     6481 ttcatacttt tcttctatta gaatgcaaaa ttatgctatc aaatcaagct taaaaatttt
     6541 ttaaaatttt tacaaaaaat acttgcaacc gttttctatt tgtgctatac taagctcata
     6601 aaggaaaacg tttgcgtttc cttatcaata aaacttgcta ttctttggga ggaatacact
     6661 atgtcatcta aatttatgaa gagcactgcg gtgcttggaa ctgctacact tgctagcttg
     6721 cttttggtag cttgcggaag caaaactgct gataagcctg ctgattctgg ttcatctgaa
     6781 gtcaaagaac tcactgtata tgtagacgag ggatataaga gctatattga agaggttgct
     6841 aaagcttatg aaaaagaagc tggagtaaaa gtcactctta aaactggtga tgctctagga
     6901 ggtcttgata aactttctct tgacaaccaa tctggtaatg tccctgatgt tatgatggct
     6961 ccatacgacc gtgtaggtag ccttggttct gacggacaac tttcagaagt gaaattgagc
     7021 gatggtgcta aaacagacga cacaactaaa tctcttgtaa cagctgctaa tggtaaagtt
     7081 tacggtgctc ctgccgttat cgagtcactt gttatgtact acaacaaaga cttggtgaaa
     7141 gatgctccaa aaacatttgc tgacttggaa aaccttgcta aagatagcaa atacgcattc
     7201 gctggtgaag atggtaaaac tactgccttc ctagctgact ggacaaactt ctactataca
     7261 tatggacttc ttgccggtaa cggtgcttac gtctttggcc aaaacggtaa agacgctaaa
     7321 gacatcggtc ttgcaaacga cggttctatc gcaggtatca actacgctaa atcttggtac
     7381 gaaaaatggc ctaaaggtat gcaagataca gaaggtgctg gaaacttaat ccaaactcaa
     7441 ttccaagaag gtaaaacagc tgctatcatc gacggacctt ggaaagctca agcctttaaa
     7501 gatgctaaag taaactacgg agttgcaact atcccaactc ttccaaatgg aaaagaatat
     7561 gctgcattcg gtggtggtaa agcttgggtc attcctcaag ccgttaagaa ccttgaagct
     7621 tctcaaaaat ttgtagactt ccttgttgca actgaacaac aaaaagtatt atatgataag
     7681 actaacgaaa tcccagctaa tactgaggct cgttcatacg ctgaaggtaa aaacgatgag
     7741 ttgacaacag ctgttatcaa acagttcaag aacactcaac cactgccaaa catctctcaa
     7801 atgtctgcag tttgggatcc agcgaaaaat atgctctttg atgctgtaag tggtcaaaaa
     7861 gatgctaaaa cagctgctaa cgatgctgta acattgatca aagaaacaat caaacaaaaa
     7921 tttggtgaat aaaaaatttg ttcaaggggg gtggaaatca aatccccctt tgaatttatc
     7981 aatagagaca caaataattt agctttctta taaaaaagta gtatcctatg aaaggagtta
     8041 atatggaaaa gcaacaacct agtaaagcag ccctgctgtc tatcattcct gggttaggac
     8101 agatttacaa taaacaaaaa gccaaaggtt ttatcttcct tggtgtaacc atcgtatttg
     8161 tcctttactt cctagcactt gcaacccctg aattgagcaa cctcatcact cttggtgaca
     8221 aaccaggtcg tgataattcc ctctttatgc tgattcgtgg tgccttccat ctaatctttg
     8281 taatcgttta tgtactcttt tatttctcaa atatcaaaga tgcacatacg attgcaaaac
     8341 gcattaacaa tggaattcca gttccacgca cactcaaaga catgatcaaa gggatttatg
     8401 aaaatggctt cccttacctc ttgatcattc catcttatgt tgccatgacc ttcgcgatta
     8461 tcttcccagt tatcgtaacc ttgatgatcg cctttaccaa ctacgacttc caacacttgc
     8521 caccaaacaa gttgttggac tgggttggtt tgaccaactt tacaaacatt tggagcttga
     8581 gtaccttccg ttctgccttt ggttctgttc tttcttggac tatcatttgg gctttggcag
     8641 cttctacttt acaaatcgta attggtatct tcacagctat cattgccaac caaccattta
     8701 tcaaaggaaa acgtatcttt ggtgttattt tccttcttcc ttgggctgtc ccagccttca
     8761 tcactatctt gacattctca aacatgttta acgatagtgt cggtgctatc aacactcaag
     8821 tattgccaat cttggctaaa ttccttcctt tccttgatgg agctcttatt ccttggaaaa
     8881 cagacccaac ttggactaag attgccttga ttatgatgca aggttggctc ggattcccat
     8941 acatctacgt tttgactttg ggtatcttgc aatctattcc taacgacctt tacgaagcag
     9001 cttatattga cggtgccaac gcttggcaaa aattccgcaa catcactttc ccaatgattt
     9061 tggctgttgc ggcacctact ttgattagcc aatacacctt caactttaac aacttctcta
     9121 tcatgtacct cttcaatggt ggaggacctg gtagtgtcgg aggtggagct ggttcaaccg
     9181 atatcttgat ctcatggatc taccgtttga caacaggtac atctcctcaa tactcaatgg
     9241 cggcagctgt taccttgatt atctctatca ttgtcatctc aatctctatg atcgcattca
     9301 agaaactaca cgcatttgat atggaggacg tctaagatga ataactcaat taaactcaaa
     9361 cgtagactga ctcaaagcct tacttacctt tacctgattg gtctatcaat tgtaattatc
     9421 tatccactgt tgattaccat tatgtcagcc tttaaagcag gtaacgtctc agcctttaaa
     9481 ctagatacta atatcgacct caattttgat aactttaaag gcctcttcac tgaaaccttg
     9541 tacggtactt ggtacctcaa cactttgatt atcgccttaa ttaccatggc tgttcaaaca
     9601 agtatcatcg tacttgctgg ttatgcctac agccgttaca acttcttggc tcgtaaacaa
     9661 agtttggtct tcttcttgat catccaaatg gtgccaacta tggccgcttt gacagccttc
     9721 ttcgttatgg cgcttatgtt gaacgccctt aaccacaact ggttcctcat cttcctctac
     9781 gttggtggtg gtatcccgat gaatgcttgg ctcatgaaag gctacttcga tacagtgcca
     9841 atgtctttag acgaatctgc aaaactagac ggtgcaggac acttccgccg cttctggcaa
     9901 attgttcttc cacttgttcg cccaatggtt gccgtacaag ctctctgggc cttcatggga
     9961 cctttcgggg actacatcct ctctagtttc ttgcttcgtg agaaagaata ctttactgtt
    10021 gccgtaggtc tccaaacctt cgttaacaat gcgaaaaact tgaagattgc ctacttctca
    10081 gcaggtgcta tcctcatcgc ccttccaatc tgtattctct tcttcttcct acaaaagaac
    10141 tttgtttcag gacttacaag tggtggcgac aagggataat ttatccccgc cacccttttt
    10201 cattttatac tcttcgaaaa tctcttcaaa ccacgtcagc tttatctcca acctcaaagt
    10261 tgtgctttga gcaacctgtg gctagtttgc actttgattt tcattgatta ttagcaattg
    10321 tcactgtaaa taatatcctt gtagcaagca atttttctcc tagacttgaa ataaagcgca
    10381 tttctctata taataatact catatagaaa acacctttta gaaagatacc tatgcttcca
    10441 tatccatttt cctatttttc aagtatttgg gggtttcgta agcccctgtc caaacgtttc
    10501 gagctcaact ggtttcaact tctctttacc agtatcttcc ttatcagctt atctatggta
    10561 cccattgcta tccaaaacag ctcccaggag acctatccgc tagaaacttt tatcgataat
    10621 atctatgaac ctctgacaaa tgaggttgtc caggatctct ctgaacatgc tacaattgtc
    10681 gatggcacat taacttatac tggaacagct agtcaagccc cttctgttgt gattggtcca
    10741 agtcaaatca aggaattacc taaggacttg caactgcatt tcgatacaaa tgagctagtc
    10801 atcagcaagg aaagcaagga actgacccgc atctcttacc gagccattca gactgagagt
    10861 ttcaaaagca aagacagctt gacccaagca atttctaaag actggtacca acaaaatcgt
    10921 gtctatatca gcctcttcct agttctcggt gcgagcttcc tctttggttt gaatttcttt
    10981 atcgtctctc taggagctag tcttctcctt tatatcacta agaaatcacg cctcttttca
    11041 tttagaacct ttaaagagtg ctatcacttt atcttgaact gtttaggatt gccgactctg
    11101 attacactta ttttgggatt atttggccaa aatatgacaa ccctgattac tgtacaaaat
    11161 attctttttg ttctgtatct ggtcactatc ttttataaaa cacatttccg tgattcaaat
    11221 taccataaat aggagatttt tatgcccgtt acgattaaag acgtggccaa ggctgctggt
    11281 gtttcgcctt caaccgtaac ccgtgttatt caaaataaat caaccattag cgacgaaaca
    11341 aaaaaacgcg ttcgcaaagc tatgaaggaa ctcaactacc acccaaacct caacgctcgt
    11401 agcttggtaa gcagctatac tcaggttatc ggattagttc ttcctgatga ctcagacgcc
    11461 ttctaccaga atcctttctt tccatcggtt ctacgtggca tctctcaagt cgcatctgaa
    11521 aaccactatg ccattcagat agcaacaggg aaagatgaga aggagcgtct caacgctatt
    11581 tcacaaatgg tctacggcaa gcgtgtagat gggctaatct ttctctatgc ccaagaagaa
    11641 gaccctctcg taaaactcgt cgcagaagaa cagttcccct tccttatctt aggtaaatct
    11701 ctatctcctt tcatcccact tgtcgacaac gacaatgttc aagctggttt tgatgcgact
    11761 gaatatttca tcaaaaaagg ctgcaaacgc attgccttta tcggaggaag taaaaagctc
    11821 ttcgtgacca aagaccgttt aacaggctat gaacaggcgc ttaaacatta caaacttacc
    11881 actgacaaca atcgcatcta ctttgccgac gagtttctgg aagaaaaggg ctataaattt
    11941 agcaagcgat tattcaagca cgatccacaa attgatgcta tcatcacaac cgatagcctc
    12001 ctagctgaag gtgtttgtaa ctatattgcc aaacaccagc tggatgtccc tgttctcagc
    12061 tttgactcgg ttaatcccaa gctcaacttg gcagcctatg tcgatatcaa tagtttagag
    12121 cttggtcgtg tttcccttga aactattctc cagattatta atgataataa aaacaataaa
    12181 caaatttgtt accgtcaatt gatcgcccac aaaattatcg aaaaataaga gactgggcaa
    12241 aaagtcgtta aaagcaaaaa cgcatagtat caggtattga aaaaacttga tactatgcgt
    12301 tttaatgtgg gaagatttac ttccttttct actgaaattg agtcttttcc caagatcttt
    12361 ttatactcaa tgaaaatcaa agtgcaaact aggaagctag ccgcaggttg ctcaaaacac
    12421 tgttttgagg ttgtagatga aactgacgaa gtcagctcaa aacatggttt tgaggttgta
    12481 gatgaaactg acgaagtcag taaccatacc tacggcaagg tgaagctgac gtggtttgaa
    12541 gagattttcg aagagtatta atcactaatt atctatctca acaaatcttc ctagaatatg
    12601 aacattttcc gagacagaga caaaggagct tggatccact tgtgtcataa tctgtttaaa
    12661 ttcattaaac tctgcacgtg taatgacagt gattaaaact gcctttctct cgtgattata
    12721 ggttccttct gcatcgtgga tcatggttgc tccgcggtgc aattttttat ggattttttc
    12781 aattaccttc tctggatgat ttgtcacaat catggcctgc atacgctttt gcttagtaaa
    12841 gactgcgtct gtcacacggc tagagacaaa gatggtaatc atagaataaa gagcgtattt
    12901 ccaaccaaag gttaaacctg ctatcagcat gatagttcca tttaccaaga aagaaatact
    12961 accgacattc ttacccgttt tcttgcgaat agtcaggctg acgatatccg tcccaccact
    13021 ggagatattg tttcgaagag caaaaccaat ccccaaaccc ataacaacac ccccaaaaag
    13081 ggaattgata atgggatcct ccgtcaaggt tgccacaggg acaaactgga taaagaagga
    13141 actcatagat accgtgataa aggtaaagac ggtgaactta tggccaatct gataccaagc
    13201 taagaccatc aaagggaagt taatggcgta gaagcttagc gaaatcggaa tatgaaaacc
    13261 aaaccagtga ttactcaagg cagagataat ctgtgccaga cctgttgcac cactcgaata
    13321 cacatgccct ggttggaaaa agaaattaac tgctactgct gataaaaaac catagaccag
    13381 agaggccgaa atcttctcat catacttttc tcgagagata ctttgtaaga cacgtaaaat
    13441 ttttatctga taagcaaagc ggcgcagata atagcgccac cgcttaattc gttttgtttg
    13501 tttcatcttc ttctacttgt aagctgagtt cctctagttg tttgagagcg actgttgatg
    13561 gagcttgtgt cattgggtca gttgccttgt tgttcttagg aaaggcaatg acttcacgga
    13621 tattttcttc tccagcaagc aacatgacaa aacggtcaag cccgatagcc aaaccaccgt
    13681 gtggtgggaa accatagtcc atggcttcaa gaaggaaacc aaactggtca ttggcttctt
    13741 cagttgagaa accaagagcc ttgaacatgc gttcttgaag gtctttttgg ttgatacgaa
    13801 ggctaccacc accaagctca taaccgttca agacgatatc gtaagcaatg gcacgaacct
    13861 tagccaaatc accttctaat tcgtgagcag tctcttcctg tggaagggtg aaaggatggt
    13921 gggcgctcat gtagcggcct tcttcttcag accattcaaa catcggccag tcaaccaccc
    13981 aaaggaagtt gaacttatca ttatcaatca agccaagctc tttagcaata cgtccacgaa
    14041 gggcacccag tgttgcatta gccacttcaa gcgtatccgc cacaaagaga accaagtcct
    14101 tatcttcaag agcaagcgct gttgtcaatt cttcttggat accagtcaag aacttggcaa
    14161 ctggtccgtt taattctcca tcaaccacct tgacccaagc aagacctttg gcaccatact
    14221 gtttggctac ttccgtcatc ttgtcgatgt ctttacgtga atagttgtcc gcagctcctt
    14281 tgaccacaat cgcttttaca gcaggtgctt ctgaaaagac tttaaagtct acacctttga
    14341 ccacttctgt caagtcctga agcaacatgt caaaacgagt atctggcttg tcagaaccgt
    14401 aaagagccat agcatcatcg tatttcatac gagggaacgg tagcgttact tcgatgcctt
    14461 ttgtttcctt catcacgcgc gcgatcaagc cttctgtaat atcttggatt tcttgctcag
    14521 taaggaagga cgtttccaag tcgacctgag taaattcagg ctggcggtct ccacgcaagt
    14581 cctcgtcacg gaaacattta acgatttggt agtaacggtc aaaaccagca ttcatcaaga
    14641 gctgtttcgt gatttgtgga ctttgaggaa gagcgtaaaa atgcccctta ttaacacgag
    14701 acggtactaa ataatcacgc gccccttcag gcgttgactt agaaaggaat ggtgtctcca
    14761 cgtcgataaa ctccaactca tccaaatagt tgcggataga gtgggtcacc ttggcacgaa
    14821 gtttaagatt ttccaacatt tctggacgac gaaggtcaag gtaacggtaa cgcaaacgtg
    14881 tatcgtcatt tgcctcaatg ccatccttaa tctcaaatgg tgttgtctta gctgtgttaa
    14941 gcacaataag agctgtcacg tttaactcaa ccgcaccagt tggcaactta tcattggctt
    15001 gctcacgcgc agcgacctga ccagtcacct caataacaaa ttcgctacga aggctttcag
    15061 ctgttgccat aacctctgca gatacttttt cagggttgat aaccaactgc atgattcctt
    15121 cacggtcacg aagatcgata aagatcaaac caccaaggtc acgacgacgg ccaacccatc
    15181 ctttcaaggt tatttcttgt ccgatgtgtt cctcacgaac acgaccagca tacatactac
    15241 gtttcattat ttctctcctc ttttattctg ttactatttt accataaaag cgcaggctct
    15301 tcatgaaaat catcagaaaa gtttgccagt ctttaaaagt caggtgaaag ccctaaaaat
    15361 tagcgctaat actcttcgaa aatctcttca aaccacgtca gcgtcgcctt accataggta
    15421 tggttactga cttcgtcagt ttcatctaca acctcaaaac catgttttga gctgacttcg
    15481 tcagtttcat ctacaacctc aaaaccatgt tttgagctga cttcgtcagt tctatccaca
    15541 acctcaaaac agtgttttga gcaacctgcg gctagcttcc tagtttgctc tttgattttc
    15601 attgagtata atacaaaaat ccgatgaact tcaccggact cttttatttt gaatttttgc
    15661 ctgctttacg cttttcagcg atttcggctg cctttcgagg caagacaatt tccgttatgt
    15721 aagccgtccc aaaacgcagt acacctgcaa taggagcaaa gacaactgct agatagttat
    15781 agaagaaatc gcctttgaag gcataagcta gcgctccaat gatgaaaaat agaacgactg
    15841 cctgaatcac tgctaataaa attactcgtt tcatgtgacc tcctgactct attatagcat
    15901 gagaatcatc aaaaagccga ctaaattatt caaagcgtga agagaaatac tgtagaccag
    15961 accttttctg ctaacgtaag ccaaacccaa actaaaacca aggctaaaat agacaaaaaa
    16021 ttgttgcaca tcacctggaa aatgaatcaa ggcaaataga agactagata ccagaagaaa
    16081 aatcagggtt cgtttactat tgtcctgctt aggaaagaga tagcgtgcta acatccctct
    16141 aaaaacaatc tcttccgtca aaggagcaaa aataaccaca gcaaagaatg agaaaagtgg
    16201 ttgagacaag gtcaagtctg tcgctatttg ctgatttact gaaggatcat ctggcaagaa
    16261 gaattgaacg accagagata agaaccaaac caaggcagga agccaaataa atcggttaaa
    16321 gccgctcttc tcaatataaa caggagcttt ctgataccat ttgtaaatgc cgtacacata
    16381 tactccagcc aagaccacat agagtagagt aacagcatag ggtgaagcgc ctaaagcaag
    16441 cgacgcagtc gcgagcccct gaataaagcc atagataaag aaaaaggata gaagggctag
    16501 aagaatccag ccaaggtttt taagtaattt catagataac tcctttattt gaaataacgt
    16561 tttaccatag gtaactgcat cacattgata taaacatgga tggctcctac aagcaagaaa
    16621 gctagtaact gaatctctcc tgtcaagaaa gaaatgataa taagaaaaat atataaggct
    16681 ggtaagacat attggtgtaa ttggaataaa attcgaaaac tctgttccaa attagcctga
    16741 cgctcccctt catcataaga atttatatag ttcaagacat cctttggtgt agcgaaaaat
    16801 tccaaatcaa actgacgaac aatcgcaatg gttttaaaaa gagatttttg agcgactaag
    16861 aataccacaa agagtaagaa agaaaggaaa aatgtttgag ggtttgtatg caatataatc
    16921 acctcactta atgaaataaa aatagccaat ggaatcgcta cacctgtaat attaaaagca
    16981 atggttccaa actcaagatt ccgatacatt tgcacataat aggtttcatt cagatcgtca
    17041 tccatttcct cttgatacaa ggaatgaaat tttctgcttt tctttaagaa attgaaagtc
    17101 aaaaacatac taatgaaacc tatcagtaaa caaatagctg atatccatgg catcaaggct
    17161 tttacatcta aaataatttc gtgggattcg acacgtgcct taaacatccc tacaaacatg
    17221 cccaagaacc cccccaagac aatagacatc aaaaataaca atctacgttt ctttttcata
    17281 ttcattctcc tttttcactt gctagatttt tggatttctt ttcaatccat tcaattactg
    17341 ggatgagagc aaagtagacc caaacaaatt ggtcgctttg atagggatta aaccagctta
    17401 ggtccatccc aatcagtaga aatacgctga ctaataaagc tatgaccact acataataaa
    17461 tcactttata cttgttcatc actcgtcctc ctccaaacga aataccgatt cgactgtttc
    17521 gttgaaaatt tgagatattt tcagggcaat gataatggat ggggtgtact catcccgttc
    17581 tagtaggcta atggtctgtc tggaaacccc tgccagtttg gctaggtcgg tttgattgag
    17641 accatcgcga gctcgaagct cttttagacg attttttagt tgcacgttac acacctactc
    17701 tccgtcaaat tcaacggttt ggatatcttc aatacgttgc aacttgaatt tttcttttcc
    17761 cgtattatca acactacgta gtttgaccca ttcctcatca acatccacaa cttcccagtt
    17821 atctggccca atatacactc ccgttataat tggttccttt ccaatcattt cttgtaataa
    17881 tctcgacatt tctgcgtttc ctttctcttt tcgctcaagt tttttgattt tattctctag
    17941 tttcttgatt tttttagaat tattagaata aaagaaaatc ataaatagta taaatcctag
    18001 tacccacatt ataactcctt tctgcttcct atttcttaac ttgaattcat tgtaacatat
    18061 ctttttcttt ttgacaagta tatttgtcaa aaagtttatg atttttgtca ttttgcaaaa
    18121 gaaaaaggtc aggagtaagt tcctgaccac tttatctatc attaatactc ttctaaaatc
    18181 tcttcaaacc acgtcagctt caccttgccg taggtatggt t
//
LOCUS       DAVLCS010000038        18155 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLCS010000038 DAVLCS010000000
VERSION     DAVLCS010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18155
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.038"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            5..75
                     /locus_tag="VXC78_001612"
     tRNA            5..75
                     /locus_tag="VXC78_001612"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="VXC78_001613"
     tRNA            110..183
                     /locus_tag="VXC78_001613"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="VXC78_001614"
     tRNA            266..355
                     /locus_tag="VXC78_001614"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="VXC78_001615"
     tRNA            366..439
                     /locus_tag="VXC78_001615"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="VXC78_001616"
     tRNA            443..515
                     /locus_tag="VXC78_001616"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="VXC78_001617"
     tRNA            528..608
                     /locus_tag="VXC78_001617"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="VXC78_001618"
     tRNA            613..683
                     /locus_tag="VXC78_001618"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="VXC78_001619"
     tRNA            698..770
                     /locus_tag="VXC78_001619"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            784..855
                     /locus_tag="VXC78_001620"
     tRNA            784..855
                     /locus_tag="VXC78_001620"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:816..818,aa:Gln,seq:ttg)
     gene            865..948
                     /locus_tag="VXC78_001621"
     tRNA            865..948
                     /locus_tag="VXC78_001621"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:899..901,aa:Leu,seq:caa)
     gene            1055..2332
                     /locus_tag="VXC78_001622"
     CDS             1055..2332
                     /locus_tag="VXC78_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV0583657.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2408..3892
                     /locus_tag="VXC78_001623"
     CDS             2408..3892
                     /locus_tag="VXC78_001623"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV0583658.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3953..5233
                     /locus_tag="VXC78_001624"
     CDS             3953..5233
                     /locus_tag="VXC78_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0583659.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5237..5857
                     /locus_tag="VXC78_001625"
     CDS             5237..5857
                     /locus_tag="VXC78_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0583660.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6023..7135
                     /locus_tag="VXC78_001626"
     CDS             6023..7135
                     /locus_tag="VXC78_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0583661.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7458..7883
                     /locus_tag="VXC78_001627"
     CDS             7458..7883
                     /locus_tag="VXC78_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0583662.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7894..8253
                     /locus_tag="VXC78_001628"
     CDS             7894..8253
                     /locus_tag="VXC78_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV0583663.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8360..9004
                     /gene="pcp"
                     /locus_tag="VXC78_001629"
     CDS             8360..9004
                     /gene="pcp"
                     /locus_tag="VXC78_001629"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0583664.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(9032..9889)
                     /locus_tag="VXC78_001630"
     CDS             complement(9032..9889)
                     /locus_tag="VXC78_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV0583665.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10019..11161
                     /gene="tgt"
                     /locus_tag="VXC78_001631"
     CDS             10019..11161
                     /gene="tgt"
                     /locus_tag="VXC78_001631"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV0583666.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11259..13076
                     /locus_tag="VXC78_001632"
     CDS             11259..13076
                     /locus_tag="VXC78_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0583667.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13229..14380
                     /gene="nagA"
                     /locus_tag="VXC78_001633"
     CDS             13229..14380
                     /gene="nagA"
                     /locus_tag="VXC78_001633"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV0583668.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14543..15601
                     /locus_tag="VXC78_001634"
     CDS             14543..15601
                     /locus_tag="VXC78_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0583669.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15752..16117
                     /locus_tag="VXC78_001635"
     CDS             15752..16117
                     /locus_tag="VXC78_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV0583670.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16193..17134
                     /locus_tag="VXC78_001636"
     CDS             16193..17134
                     /locus_tag="VXC78_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV0583671.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17082..18098
                     /locus_tag="VXC78_001637"
     CDS             17082..18098
                     /locus_tag="VXC78_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV0583672.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
BASE COUNT         5260 a         3243 c         4237 g         5415 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tattggggta tagccaagcg gtaaggcaag ggactttgac tccctcatgc gttggttcga
      841 atccagctac cccagttact atttgccggc gtggcggaat tggcagacgc gctggactca
      901 aaatccagtg tccgcaagga cgtgccggtt cgaccccggc cgccggtata gtatagtgtt
      961 aggaacgttg ttattcttcg ttcctttttt atattatttt tggtataatt atagttattc
     1021 aaattttatt tagattaaga aagtgtaggg gagtatgtct tgttctatcg atttattaaa
     1081 acatcggtat ttgaaaaata ttaaagaaaa tcctgaattg tttgtcggaa ttgagttgga
     1141 gtatcctgtt gcaagtttag aaggggatgc tacagatgtt gaagttatga aggatctatt
     1201 tcattattta gtttctactt tggatctcac cgtagcaaag gtagatgatt ttggcaatct
     1261 gatccagtta gtagatccga taagtcagga tgctatttta tttgaagttt cctatacaac
     1321 gattgagttt gcatttggta aggctgaaac gattcaagag gtcgaaaatc gtttcaataa
     1381 ttatatgaat gtaattcaga gaaagttagc tgaatcaaat catgctattg ttggctgtgg
     1441 tatccatccc aactgggata aaaatgagaa ttgtccagtg gcttatccac gctatcagat
     1501 gttgatggat tatttgaatt tgagtagaaa tattattaaa tcagatttac atcatttccc
     1561 tgaatatggt acttttatct gtgggagcca ggttcagctg gatatttcaa aaaccaacta
     1621 cttacgggtg attaatgctt ttactcaaat tgaagcggct aaggcttatt tatttgcaaa
     1681 ctctgaattt tcgggtgcgg attgggatac gaaaatttca agggatattt tctgggaaga
     1741 atctatgcat ggtatctatc cagagaatgt tggggtcaat gctagactcc ttaatgatga
     1801 agctgatttt tttgactatc taaatcattc tgcgattttt actgcggaac gtgatgggca
     1861 gacctattat ttttatccta ttcaggctgg ggactatttg gctacgtccg aaatccaagc
     1921 atttgctctg aatggggatg aggttattat ttacccccaa gagaaggatt ttgaaactca
     1981 tcgtagttac cagtaccaag atttaacgac tcgaggaaca gttgagtttc gtagtgtgtg
     2041 tacacagcca cttgatagga cttttgcttc tgcagctttt cacttgggat tattggttaa
     2101 tttagacaag ttagaagctt acttagaaac agcacctttc tttaaagtat ttggttatga
     2161 ttacaagtct ttaaggagac aattttctaa gaaaaatctt acagatgagg aagaaactac
     2221 gattattgaa ttttccaaag acttactcct actagctgag gagggactag tggtgagaaa
     2281 taaggaagaa atgacctatt tacagccttt gagagaagaa ttgagcctat aatttctctt
     2341 ataaagggag aattttctga aaaatcatga tataatggac gagactatag ataaaggata
     2401 gagagtaatg acattagttt atcaatcaac gcgtgatgcc aacaatacag taactgccag
     2461 ccaagcaatt ttgcaaggtt tggcgacgga cggcggtttg tttacaccgg atacttatcc
     2521 aaaggtagat ttgaactttg acaaattgaa agatgcttct taccaggaag ttgctaagct
     2581 agttttgtca gcatttttag atgactttac agttgaggag ttggactact gtatcaacaa
     2641 tgcctacgat agcaaatttg atactccagc tattgcacca ttagtgaaat tagatgggca
     2701 atacaatttg gaacttttcc atggttcaac gattgccttt aaggatatgg ccttgtctat
     2761 tttgccatac tttatgacga ctgctgctaa gaaacatggt ttggagaaca agattgttat
     2821 cttgacagcg acatctggtg acacggggaa agctgctatg gcggggtttg cgaatgtgcc
     2881 tggtactgag attatcgtct tttatccaaa ggatggtgtc agcaagattc aagagttaca
     2941 aatgaccact cagactggcg acaatactca tgttattgct attgatggta actttgacga
     3001 tgcgcaaaca aatgtgaagc acatgtttaa cgacgtggct cttcgtgaaa aattgactac
     3061 caacaagttg caattttcat cagctaactc tatgaacatt ggtcgtctgg tgccacaaat
     3121 tgtttattat gtttatgctt acgctcaatt ggttaagact ggtgaaattg tagctggtga
     3181 aaaggttaac ttcacagtac caacaggaaa ctttggaaat atcttggctg ccttttatgc
     3241 caaacaaatt ggtttgccag ttggtaaatt aatctgtgct tcaaatgaca acaatgtttt
     3301 gacagacttc tttaaaacac gtgtctatga caaaaaacgt gagtttaagg taacaaccag
     3361 cccatctatg gatatcttgg tatcttcaaa cttggagcgc ttgattttcc atcttttggg
     3421 aaataatgct gaaaagacaa ctgaacttat gaatgccttg aacacgcaag gacaatataa
     3481 gttgacagac tttgatgcag agattttgga cctctttgca gctgaatatg cgactgagga
     3541 agaaacggca gcagagatca agcgtgtttg tgagttagat tcttatatcg aggaccctca
     3601 tacagctgtt gcttcagcag tttataaaaa ataccaatcg gccactggag atgtaactaa
     3661 gacagtgatt gcttcaacag ctagtccata caagttccca gtagttgcag tagaagctgt
     3721 aactggaaaa gcaggtttaa cagactttga agccttggct caattacatg aaatctcagg
     3781 cgttgcagtg ccaccagcag ttgatgggct tgaaatagct ccaattcgtc acaagacaac
     3841 agtggcagct gctgacatgc aagcagcggt tgaggcttat ttaggacttt aagacagagg
     3901 gagcaaactc ggttgggaaa ccaactgagt ttcttttcat caggaggaga gattgtttaa
     3961 gaaaaataaa gacattctta atattgcatt gccagctatg ggtgaaaact ttttgcagat
     4021 gctaatggga atggtggaca gttatttggt tgctcattta ggattgatag ctatttcagg
     4081 ggtttcagta gctggtaata ttatcaccat ttatcaggcg attttcatcg ctctgggagc
     4141 tgctatttcc agtgttattt caaaaagcat agggcagaaa gaccagtcga agttggccta
     4201 tcatgtgact gaggcgttga agattacctt actattaagt ttccttttag gatttttgtc
     4261 catcttcgct gggaaagaga tgataggact tttggggacg gagagggatg tagctgagag
     4321 tggtggactg tatctatctt tggtaggcgg atcgattgtt ctcttaggtt taatgactag
     4381 tctaggagcc ttgattcgtg caacgcataa tccacgtctg cctctctatg ttagtttttt
     4441 atccaatgcc ttgaatattc ttttttcaag tctagctatt tttgttctgg atatggggat
     4501 agctggtgtt gcttggggga caattgtgtc tcgtttggtt ggtcttgtga ttttgtggtc
     4561 acaattaaaa ctgccttatg ggaagccaac ttttggttta gataaggaac tgttgacctt
     4621 ggctttacca gcagctggag agcgacttat gatgagggct ggagatgtag tgatcattgc
     4681 cttggtcgtt tcttttggga cggaggcagt tgctgggaat gcaatcggag aagtcttgac
     4741 ccagtttaac tatatgcctg cctttggcgt cgctacggca acggtcatgc tgttggcccg
     4801 agcagttgga gaggatgatt ggaaaagagt tgctagtttg agtaaacaaa ccttttggct
     4861 ttctctgttc ctcatgttgc ccctgtcctt tagtatatat gtcttgggtg taccattaac
     4921 tcatctctat acgactgatt ctctagcggt ggaggctagt gttctagtga cactgttttc
     4981 actacttggg acccctatga cgacaggaac agtcatctat acggcagtct ggcagggatt
     5041 aggaaatgca cgcctccctt tttatgcgac aagtatagga atgtggtgta tccgcattgg
     5101 gacaggatat ctgatgggga ttgtgcttgg ttggggcttg cctggtattt gggcagggtc
     5161 tctcttggat aatggttttc gctggttatt tctacgctat cgttaccagc gctatatgag
     5221 cttgaaagga taggaaatgc aaaaaacagc ttttatttgg gatttagacg ggactttatt
     5281 ggactcttac gaagcgattt tatcagggat tgaggagact tttgctcagt tttctattcc
     5341 ttatgataag gagaaggtga gagagtttat cttcaagtat tcggtgcaag atttgcttgt
     5401 gcgggtggca gaagatagaa atctggatgt tgaggtgcta aatcaggtgc gtgcccagag
     5461 tctggctgag aagaatgctc aggtagtttt gatgccaggt gcgcgtgagg tgctagcttg
     5521 ggcagacgaa tcaggaattc agcagtttat atatactcat aaggggaaca acgcttttac
     5581 cattctcaag gacttggggg tggaatccta ttttacagag attttaacca gtcagagtgg
     5641 ctttgtgcgg aagccaagtc cagaagcggc tacctatctg ctagataagt atcagttgaa
     5701 ttctgataat acttattata taggggatcg gactctggat gtggaatttg cccagaatag
     5761 tgggattcaa agcatcaact ttttagagtc tacttatgaa gggaatcaca ggattcaagc
     5821 gttagcagat atttcccgta tttttgagac taagtgataa aaagattgtg tcagttttgt
     5881 gacagagacc taacaaacta tttcaagtaa cctagtttgt tacaaggaat agacagttct
     5941 gttaaatagg cccgagaggg ctttttttct acattttttg tgttatgata gacaggtact
     6001 catttgaaag gaatttgaaa gaatgaagaa aagaatgtta ttagcgtcaa cagtagcctt
     6061 gtcatttgcc ccagtattgg caactcaagc agaagaagtt ctttggactg cacgtagtgt
     6121 tgagcaaatc caaaacgatt tgactaaaac ggacaacaaa acaagttata ccgtacagta
     6181 tggtgatact ttgagcacca ttgcagaagc cttgggtgta gatgtaacag tgcttgcgaa
     6241 tctgaacaaa atcactaata tggacttgat tttcccagaa actgttttga caacgactgt
     6301 caatgaagca gaagaagtaa cagaagttga aatccaaaca cctcaagcag actctagtga
     6361 agaagtgaca actgcgacag cagatttgac cactaatcaa gtgaccgttg atgatcaaac
     6421 tgttcaggtt gcagaccttt ctcaaccaat tgcagaagtt acaaagacag tgattgcttc
     6481 tgaagaagtg gcaccatcta cgggcacttc tgtcccagag gagcaaacga ccgaaacaac
     6541 tcgcccagtt gaagaagcaa ctcctcagga aacgactcca gctgagaagc aggaaacaca
     6601 agcaagccct caagctgcat cagcagtgga agtaactaca acaagttcag aagcaaaaga
     6661 agtagcatca tcaaatggag ctacagcagc agtttctact tatcaaccag aagagacgaa
     6721 aataatttca acaacttacg aggctccagc tgcgcccgat tatgctggac ttgcagtagc
     6781 aaaatctgaa aatgcaggtc ttcaaccaca aacagctgcc tttaaagaag aaattgctaa
     6841 cttgtttggc attacatcct ttagtggtta tcgtccagga gacagtggag atcacggaaa
     6901 aggtttggct atcgacttta tggtaccaga acgttcagaa ttaggggata agattgcgga
     6961 atatgctatt caaaatatgg ccagccgtgg cattagttac atcatctgga aacaacgttt
     7021 ctatgctcca ttcgatagca aatatgggcc agctaacact tggaacccaa tgccagaccg
     7081 tggtagtgtg acagaaaatc actatgatca cgttcacgtt tcaatgaatg gataaacccg
     7141 acttgataac atcattttga cgaatgagat ctagctttcg tgatggaaag cgattctcgt
     7201 tcgttttttc tttgtcatac tcttcgaaaa tctcttcaaa ccacgtcagt tttatctgaa
     7261 acttcaaagc tgtgctttga gcaacctgcg actagcttcc tagtttgctt tttgattttc
     7321 attgagtatc aatttgaatg gaaaatggaa agttatcatc ttgtaatgag ttaagcaaca
     7381 ttcttgcaat ctattttact ttatatcaca attaattagt caaatattga taaatcaata
     7441 aaaagagagg ggaagaaatg ctagagattc aagatttact gtatcaactc cgcttgtctg
     7501 agcaagcgag tacgcaattg tttgaaaaaa ggcttgggat tagtttgaca cggtatcaga
     7561 ttttactgtt tttgctggag cattctcctt gtaaccaaat ggcggttcag gagcgtttga
     7621 aaattgatca ggctgctttg acacggcatt tcaaaatttt ggaaacggaa ggtttggtgg
     7681 agcgtcatcg taatcctgaa aatcagcggg aagtgttggt agaggctgcg aagtatgcca
     7741 aggagcagtt agtggtgaat ccccctctgc aacatatcag ggttaaggaa gagatagaaa
     7801 gtatcttaac agagtttgag agaacagaac tcagccgttt attaaataaa ttggttttgg
     7861 gtattgaaaa tatagaaatt taaggagaaa tagatgtcaa ttattttaac aacgatcgtt
     7921 gctttggagc atttttacat tttttatttg gaaagtattg ccacgcaatc agatgcgact
     7981 agtcgtgtat ttaatatgga aaaggaagaa ttggctcatc cgtcagtaag ttcattgttc
     8041 aaaaatcaag gaatttataa ggctctgcta ggagtctttc tcttgtatgt catttatttc
     8101 tcacagaatt tagaaattgt gactattttt gtcttatttg tgattggtgc tgcgacttac
     8161 ggctctttaa cagcggataa aaaaattatt ttgaaacaag gtggatcagc tattttggcc
     8221 ttgattagta ttttactctt taaatacact tgaaggtcga ttctaatctc gctaatcctt
     8281 tttaatccag aataagggaa atatgttata cttgttttta agaaaaaagt ctcattgaat
     8341 tggttttgag gagttagaaa tgaaagtatt agtgacgggt tttgagccct ttggagggga
     8401 aaagggcaat ccagctttgg aggccattaa aggtttacca gctgaaatcc atggtgctga
     8461 ggtccgttgg ctagaggtgc cgacagtttt tcacaaatct gctcaagtat tggaagaaga
     8521 gatgaatcgt tatcaacctg actttgtcct ttgtattggg caagctggtg gaagaactag
     8581 tttgacacct gaacgagtga ccattaatca agacgatgca tgcatttctg ataacgaaga
     8641 taatcaaccg attgaccgtc ccattcgccc agatggtgct tcggcctact ttagtagttt
     8701 gccgattaaa gcgatggttc aagctataaa aaaagagggc ttaccggcct ctgtttccaa
     8761 tacggcaggg acttttgtct gcagccattt gatgtatcag gctctctatt tggtagaaaa
     8821 gaaatctcca tatgttaagg caggttttat gcatattcct tatatgatgg aacaggtggt
     8881 gaacagaccg actactccag ctatgagttt agtggatatt cggcgaggga tagaagcagc
     8941 aatcggcgct ataatagaac atggagatca ggaactcaag ttggtaggcg gagaaactca
     9001 ttgatagaaa aaagcttgag gggaaaaacc ttcaagcttt tggacgtttt cgggccaata
     9061 ctgctcggta aaacataatt ttagtgcatt ggatataagg taggagtgaa aaactagcaa
     9121 tgccaaaggt aatccaattg aggaagtacc aaggaagaag ctgtaaatct aggacaaagt
     9181 gctggaactt gtagcccttc ataaaggaac ggctagtttt taggattcgt cttggtggga
     9241 cctgtcctag gtctagacta taacagagaa gaaattccac ctgtgaatag gcataatact
     9301 gtggaatata gaggatattt cctacaatga tcaagatgag acttgcaaga aagtagagtc
     9361 caaagaccat gaggaaacgc tcggtttcaa ctgatgagag atctagattt ggaaactcag
     9421 gatgtagggt gacgaatttt ttggctaaaa agctactata aaagaggagg taaatcccaa
     9481 gtaaattagg gatactccat aaaaagagat agaaacgttt gagaagtagg gtcaaaaagg
     9541 tttgagaaaa gcgctcctca tcaaagagag ctaggctgtt ttttacagat ggctccgttt
     9601 tagaatcttt catgagtgtc agtgttgcat agacggaact ggtcaaaaga atagtcccga
     9661 taaaggagac tagtagagga aagaggtagg tttgaagtat ttggccaagt atgctgaaaa
     9721 atggctgttc taaaacagtc ccgtggatcc gagataaggg attaagaaaa ccagataaga
     9781 tgaccagcat actgggaagg atatagagga gaaagagacg gggggtgtca gcctgaaaat
     9841 gttttgactc ctgacgaatt gtttttaaat caatttttgg atagttcatt ctcttattat
     9901 accatagttc ttatacatag ttcgtgacag ttcctacttt ttttgataaa atcatacagt
     9961 gtgtccttgg gcacactgta tgaactggga ctgtctttcc cagcttcgga ggtaaaaaat
    10021 gtcagattca ccaatcaaat atcgtttgat taagaaagaa aaacacacag gagctcgtct
    10081 gggagaaatc atcactcccc acggtacctt tccgacacct atgtttatgc cagttgggac
    10141 acaagccact gtcaaaactc agtcacctga agaattgaag gagatgggtt cgggaattat
    10201 cctatcaaac acctatcatc tctggcttcg ccctggagat gaactcattg cacgcgctgg
    10261 tggtctccac aagttcatga attgggacca gcctatcttg acagatagtg gtggttttca
    10321 ggtttattct ttagcagata gccgtaatat cacagaagaa ggagtaacct ttaaaaatca
    10381 tctaaatggt tctaagatgt tcctatcccc agaaaaagcc atctctattc agaataatct
    10441 gggttcagac atcatgatgt cctttgatga atgtcctcag ttttatcaac cttatgacta
    10501 cgttaagaaa tcgatcgagc gtaccagccg ttgggctgag cgtggtttga aggctcaccg
    10561 tcgtccacat gaccaaggtt tgtttggaat tgtgcaaggt gcaggatttg aagaccttcg
    10621 ccgccaatca gctcatgatc ttgtcagcat ggatttctca ggctactcta tcggtggttt
    10681 ggcagtggga gaaacccatg aagagatgaa tgcggtcttg gactttacaa ctcaactgct
    10741 acctgaaaat aaacctcgtt atctgatggg tgtgggagcg ccagatagct tgatcgatgg
    10801 ggtcattcgt ggggtggata tgtttgactg tgtcttaccg actcgaattg ctcgtaacgg
    10861 gacttgtatg accagtcaag gacgtttggt tgtgaaaaat gcccagtttg ctgaggactt
    10921 tacgccactg gatcctgagt gtgactgcta cacatgtaat aactatacac gcgcttacct
    10981 tcgtcacctg ctcaaggctg atgaaacctt tggtatccgc ttgactagct accacaatct
    11041 ttacttcttg cttaacctga tgaagcaagt gcgacaagcc atcatggatg acaatctctt
    11101 ggaattccgt gagtattttg tggaaaaata tggctataat aagtcaggac gtaatttcta
    11161 aaatggaatt gatataaaaa aatcctaagt tttctcttag gatttttctt ctttttttga
    11221 tagaataaag tgtacaatga aaggaagaat aaactcgtat gcgcattaaa tggttttcct
    11281 tgattaggat tataggttta cttttggtac tcttgtatca cttctttcag acgatctttc
    11341 ctggaggatt tttcggggta gatgtctttt tcacattttc aggtttcctg attacagctc
    11401 tactcattga agaattttct aagaacaatg agattgattt gataggattt tttagaagac
    11461 gcttttatcg gattgtgcca cctgtggttt tgatggtctt ggtgaccatg ccttttactt
    11521 tcttggttcg ccaagactat gttgctggaa ttggtggcca gattgcgggc gtcttaggct
    11581 ttatgaccaa cttctatgaa ctcctaacag gtgggagtta tgaatctcag ttcattcctc
    11641 atttgtttgt tcataattgg agtttggcag ttgaggttca ctactatatt ctttggggat
    11701 tggcagtttg gttcttatcc aaacaagcta aatcaaatgg tcagttgaag gggatggtct
    11761 ttctcttatc tgctgctgcc ttcttgatca gtttcttctc catgtttatt ggtagttttc
    11821 tagtgacctc ttattcctct gtttatttct ccagtttaac tcatgtctat ccattctttt
    11881 tgggaagtat gttagcaact attgtaggtg ttcgtcagac gacttccctc gtcaagcagt
    11941 tggataaaat ctgggattta cgaaagactt tggtagtttt tggaggaggc tttggtttcc
    12001 tagttctttt gactttcttt gtcaaattca cttatctttt tgcctatctt atcggcttct
    12061 tgcttgccag tcttgcagct cttgccatga ttctggcggc gcgtgtctta catgaaaaga
    12121 cacatcatat acaggagccg aagattatca gctttttagc ggatactagc tatgcggttt
    12181 atcttttcca ttggcctttc tatatcattt tctcacagtt gacatcaaat cttcttgctg
    12241 tattactgac tctgatttgt tcttatggct ttgccagtct gtcattctat gtattggaac
    12301 cttggattgc aggcaagaac acacctattt tacaaactct tcgtcccctg ccttatattc
    12361 acgcaattct tgtagcaggt acaggaatct tgaccatcat tgtctgcacg gtgaccttgt
    12421 tggcaccaca agtgggagcg tttgagacag acttgactgt caatggcttg aagcaagctg
    12481 caacaaatat tggccagacc aaggtgatgg cagaacgggc agatgcaaac agtttgggaa
    12541 ttgctgatgg cactatgtta attggtgact cagtggcttt aagggcaaat acagcactac
    12601 agacagctct tcctggagca cagattaacg cgcaggtcag cgtaacaacc aagaccgcaa
    12661 atgaaatcat gctaaataat agccagaata aatttttacc taagacggtg gtcattgcga
    12721 ctggggtaaa taatcctgag aattacaagg atgactggga cagtatcgtg aaaaatcttc
    12781 ctaagggaca ccatatgatt ttggtgactc cttatgaggg agataagaca aaagagacct
    12841 atgccatcgt tgagaaggct gctgcctata tgagagaatt ggcagagaag acaccttaca
    12901 ttacgatagc agattggaat caagttgcga aagagcatcc agaaatttgg gctggaacag
    12961 accaggttca tttcgggagt gagagtagca ctatcgaagc aggagcaaaa ttgtatgcag
    13021 atacgattgc cacagctttg cagacagctc aagacaagcc ggttaaatca aaataacttg
    13081 tattaaaaaa gagaagagtt ggagaaatcc agctctttta aaatatctcc aaaaaatagg
    13141 tctataccat ttacaaataa aaaagaaagg tttataatgt aattgacata ataaattgta
    13201 gaatcaatct tttaaggagg ttaacattat gcctaactat attaaagcgg atcagttttt
    13261 ctacccacac ggagttcgtc gaggtggtta cttggaactt gtggacggca agtttgggaa
    13321 acatgtagag cagattcctg aaggggctga ggtgattgac tatacaggtt atagcattgc
    13381 cccaggtctt gtggatactc atattcatgg atatgcaggt gtagatgtga tggacaacaa
    13441 cattgaaggt acattgcata ctatgagtga aggacttctt agtaccggtg ttaccagttt
    13501 cttacccaca actttaacag ccacttatga gcaattgctt gcagtcactg aaaatcttgg
    13561 aaaccattat aaagaagcaa caggtgctaa gattcgtggg atttattatg aaggtccata
    13621 tttcacagaa acttttaagg gggcacaaaa tccaacttat atgagagacc cgggtgttga
    13681 ggagtttcat tcttggcaaa aagcggcaaa tggcttgctt aataaaattg cccttgcacc
    13741 agaacgtgat ggggtggaag actttgttcg tacagttacg ggcgaaggtg tgacggttgc
    13801 tcttggacat tcaaacgcga cttttgatga agccaaaaaa gcagtcgatg ctggagcgag
    13861 tgtttgggtg catgcctaca atggaatgcg tgggttgact caccgtgaat tgggtatggt
    13921 tggagccatg taccaattgc cacataccta tgcagagttg atctgtgatg gtcaccacgt
    13981 agatccaaag gcttgcgaaa ttcttatcaa acaaaaagga acagaaaaca tcgctcttat
    14041 cacagactgt atgacagctg ggggattgga agacggagat tatatgttgg gagaattccc
    14101 agttgtcgtt gcaaatggaa ctgcacgcct caaatcgaca ggtaacttgg caggttctat
    14161 cctcaaactc aaagatggtt tgaagaatgt ggtcgaatgg ggaattgcga atccgcatga
    14221 agcagtcatg atggccagct tcaacccagc taaatccgtt cacatcgatg acgtctgtgg
    14281 ccaaatccgt gaaggctacg acgctgactt catcgtatta gataaagatt tggaattggt
    14341 agcaacctat ctagatggcg taaaacgtta tcaagcataa gagagaaggc agaagttaga
    14401 gactagcttc tgctttttta tacagggtac tttactggta aataaaaagt taaaaaaatc
    14461 acaaaaaaag cttgaagaaa caaagaaaaa ggcttacaat tgaactataa atattacaaa
    14521 taaaaaaacg gaggagtgct ttatgaaagc ctatacttat gttaaaccag gacttgcttc
    14581 ttttgttgat gtagacaaac cagttattcg caagccaaca gacgctattg tgcgtattgt
    14641 aaaaaccact atttgtggaa cagacctcca tattatcaaa ggggatgttc ctacttgcca
    14701 aagtggtacc attcttggcc acgaagggat tgggattgtt gaagaagttg gggaaggagt
    14761 ttccaacttc aaaaaaggcg acaaggtctt gatttcttgc gtctgtgcct gtggtaaatg
    14821 ctactactgt aaaaaaggaa tttatgccca ctgtgaagac gaagggggct ggattttcgg
    14881 tcacttgatt gatggtatgc aggctgaata tctacgtgtc cctcatgcag ataatactct
    14941 ttaccatact ccagaagact tgtcagatga agctttggtt atgctgtcag acattctgcc
    15001 tactggatat gaaattggtg tcttaaaagg gaaagtagaa cctggttgca gcgtagccat
    15061 tattggttca ggtccagttg gattggctgc tcttttaaca gcccaattct attcaccagc
    15121 taaattgatt atggtagacc tagacgataa ccgcttggaa actgccctat cattcggtgc
    15181 gactcataag gttaattctt cagaccctga aaaagccatt aaagaaattt atgatttgac
    15241 agatggtcgt ggtgtggatg tcgctatcga agctgttggt attcctgcaa catttgattt
    15301 ctgtcaaaag attatcggtg tagacggaac ggttgccaac tgtggtgtgc atggtaaacc
    15361 agttgaattc gatttagata aactttggat tcgcaacatc aatgtaacaa ctggtttggt
    15421 atctacaaat acgactccac aattgttgaa agcacttgaa agtcataaga ttgaaccaga
    15481 aaaattggta actcactatt tcaaactcag tgaaattgaa aaagcctacg aagtcttcag
    15541 taaggcagca gaccaccatg ccattaaggt cattatcgaa aacgatatct cagaagccta
    15601 agtagtaaaa atatttttgt acataagtaa atagaaattc agtcatccat cagatggctg
    15661 gattttttat caaaaaatta agaaatgagc atatttcttt ccttgtctgg cggaattggt
    15721 tataatatac ggtacaaagg aatgaatgaa tatgtatcgt gttatagaaa tgtacggaga
    15781 ttttgaaccg tggtggttct tagaaggttg ggaagaagat attgtagcaa gtagaaaatt
    15841 tgaccagtat tatgatgctc tcaaatacta caaaacttgc tggtttagat tggaacaaga
    15901 atcccctctt tataaaagta gaagcgactt gatgaccatt ttttgggacc cggaagacca
    15961 acgctggtgt gatgaatgtg atgagtattt acaacaatac cattctttgg ctcttttgca
    16021 ggatgagcag gttatcccag acgaaaaact acgctcaggc tatgaaaaac aaaccagtca
    16081 ggaaaggaat cgttcttgcc gtatgaaatt aaaatagaga aaagtaactt ttttggagtt
    16141 gcttttttta tttttctaac gctttgcgaa tagtataggt gaggaggtaa gtatggttca
    16201 agaaattgca caagaaatca ttcgttcggc tcggaaaaaa ggggcgcaag acatttattt
    16261 tgtccctaag ttagatgcct atgagcttca tatgagggta ggagacgagc gctgtaaaat
    16321 tggtagctat gattttgaaa agtttgcagc cgttatcagt cactttaagt ttgtggcggg
    16381 tatgaatgtg ggagaaaaaa gacgtagtca actgggttcc tgtgattatg cctatgacca
    16441 gaagatagcg tctctacgtt tatctactgt aggcgattat cgggggcatg agagtttggt
    16501 tatccgtttg ttgcacgatg aggagcagga cttgcatttt tggtttcagg atattgaaga
    16561 attaggcaag cagtacaggc aacggggact ctatcttttt gctggtccgg ttgggagtgg
    16621 taagacgacc ttgatgcatg aattgtccaa gtcactcttt aaaggacagc aagttatgtc
    16681 catcgaagat cctgtcgaaa tcaagcagga cgacatgctt cagttgcagt tgaacgaagc
    16741 aatcggccta acctatgaaa atctaatcaa actttccttg cgtcatcgac cagatctctt
    16801 gattatcgga gaaattcgtg acagcgagac ggcgcgtgca gtggtcagag ctagtttgac
    16861 aggtgcgaca gtcttttcaa ccattcacgc caaaagtatc cgaggtgttt atgagcgtct
    16921 gctggagttg ggtgtgagtg aagaagaatt ggcagttgtt ctgcaaggag tctgctacca
    16981 gagattaatc gggggaggag gaatcgttga ctttgcaagc agagattatc aagaacacca
    17041 agcagccaag tggaatgagc aaattgacca gcttcttaaa gatggacata tcacaagtct
    17101 tcaggctgag acggaaaaaa ttagctacag ctaagcaaaa aaatatcatc accctattta
    17161 acaatctctt ttctagcggt tttcatctgg tggagaccat ctccttttta gataggagtg
    17221 ctttgttgga caagcagtgt gtgacccaga tgcgtacagg cttgtctcag gggaaatcat
    17281 tctcagaaat gatggaaagt ttgggatgtt caagtaccat tgtcactcag ttatctctag
    17341 ctgaagttca tggcaatctt cacctgagtt tgggaaagat agaagaatat ctagacaatc
    17401 tggccaaggt caagaaaaag ttaattgaag tagcgaccta tcctttgatt ttgctgggtt
    17461 ttcttctctt aattatgctg gggctacgga attacctgct cccacaactg gatagtagca
    17521 atattgccac ccgaattatc ggtaatctgc cacaaatttt tctaggcatg gtagggcttg
    17581 tttccgtgct tgccctttta gcactaactt tttataaaag aagttctaag atgagtgtct
    17641 tttctatctt agcacgcctt ccctttattg gaatctttgt gcagacctac ttgacagcct
    17701 attatgcacg tgaatggggg aatatgattt cacagggaat ggagctgacg cagatttttc
    17761 aaatgatgca ggaacaaggt tcccagctct ttaaagaaat cggtcaagat ctggctcaaa
    17821 ccctgaaaaa tggccgtgaa ttttctcaga cgataggaac ctatcctttc tttaggaagg
    17881 aattgagtct tatcatagag tatggggaag ttaagtccaa gctgggtagt gagttggaaa
    17941 tctatgctga aaaaacttgg gaagcctttt ttacccgagt caaccgcacc atgaatttgg
    18001 tgcagccact ggtttttatc tttgtggcac tgattatcgt tttactttat gcggcaatgc
    18061 tcatgcccat gtatcaaaat atggaggtaa atttttaaaa tgaaaaaaat gatgacattc
    18121 ttgaaaaaag ctaaggttaa agcttttaca ttggt
//
LOCUS       DAVLCS010000039        17467 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLCS010000039 DAVLCS010000000
VERSION     DAVLCS010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17467
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.039"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            331..1377
                     /gene="pheS"
                     /locus_tag="VXC78_001638"
     CDS             331..1377
                     /gene="pheS"
                     /locus_tag="VXC78_001638"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV0583673.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1377..1886
                     /locus_tag="VXC78_001639"
     CDS             1377..1886
                     /locus_tag="VXC78_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0583674.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1963..4365
                     /locus_tag="VXC78_001640"
     CDS             1963..4365
                     /locus_tag="VXC78_001640"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV0583675.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISFGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(4433..5434)
                     /locus_tag="VXC78_001641"
     CDS             complement(4433..5434)
                     /locus_tag="VXC78_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0583676.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5590..6036
                     /locus_tag="VXC78_001642"
                     /pseudo
     CDS             5590..6036
                     /locus_tag="VXC78_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6162..6428
                     /locus_tag="VXC78_001643"
     CDS             6162..6428
                     /locus_tag="VXC78_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0583677.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            6689..8938
                     /gene="metE"
                     /locus_tag="VXC78_001644"
     CDS             6689..8938
                     /gene="metE"
                     /locus_tag="VXC78_001644"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV0583678.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNSITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            9002..9868
                     /gene="metF"
                     /locus_tag="VXC78_001645"
     CDS             9002..9868
                     /gene="metF"
                     /locus_tag="VXC78_001645"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV0583679.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10553..12766
                     /gene="pnp"
                     /locus_tag="VXC78_001646"
     CDS             10553..12766
                     /gene="pnp"
                     /locus_tag="VXC78_001646"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV0583680.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12782..13399
                     /gene="cysE"
                     /locus_tag="VXC78_001647"
     CDS             12782..13399
                     /gene="cysE"
                     /locus_tag="VXC78_001647"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV0583681.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13411..14295
                     /locus_tag="VXC78_001648"
     CDS             13411..14295
                     /locus_tag="VXC78_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0583682.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14382..15725
                     /locus_tag="VXC78_001649"
     CDS             14382..15725
                     /locus_tag="VXC78_001649"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV0583683.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15718..16104
                     /locus_tag="VXC78_001650"
     CDS             15718..16104
                     /locus_tag="VXC78_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV0583684.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16108..16992
                     /locus_tag="VXC78_001651"
     CDS             16108..16992
                     /locus_tag="VXC78_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV0583685.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(17039..>17467)
                     /locus_tag="VXC78_001652"
     CDS             complement(17039..>17467)
                     /locus_tag="VXC78_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0583686.1"
                     /translation="RKLSDKHFYRPTFRMHLTNKEILDKLLSYSQDLKHHYQLYQLLL
                     FHFQNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKKKIVNALQLPYSNAKLEATNN
                     LIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         5193 a         3386 c         3989 g         4899 t
ORIGIN      
        1 tcatcttatt tcaatccgct ataaagttag ataagaataa gctaacaagc agaagtaaga
       61 taggtcttgc aagaatggta aaaatctgat aaactaagtg gtaattgaat agaaatctga
      121 aagactagta gcccaaggga agtatatcag ggaggagagc cgtgactgca agctctctat
      181 atgaaagctg ggtgaattca cttgcgcatg gatttagaaa tgaaggtctg acttgtcaga
      241 tgaaaacgga tggtaccgcg tgtcaacgct ccgagtggag tttttggcat gtggttttct
      301 ttttatctac gagagactga tggaggaaat atgtcaacta ttgaagaaca attaaaagcg
      361 cttcgcgaag aaacgctgac tagcttgaag cagattactg ctggaaatga aaaagagatg
      421 caagatttgc gtgtctctgt ccttggtaaa aagggttcgc tcactgaaat cctcaaaggg
      481 atgaaagatg tttctgctga gatgcgtcca atcatcggga aacacgtcaa tgaagctcgt
      541 gatgtcttga cagctgcttt tgaagaaaca gctaagctct tggaagaaaa gaaagtcgcg
      601 gctcaactgg ctagcgagag tatcgatgtg acgcttccag gtcgtccagt tgcgactggt
      661 caccgtcacg ttttgacaca aaccagtgaa gaaatcgaag atatcttcat cggtatgggt
      721 tatcaagtcg tggatggttt tgaagtggag caagactact ataactttga acgtatgaac
      781 cttccaaaag accacccagc tcgtgatatg caggatactt tctatatcac tgaagaaatc
      841 ttgctccgta cccacacgtc tccagttcag gcgcgtgcta tggatgccca tgatttttct
      901 aaaggtcctt tgaagatgat ctcgccaggg cgtgtcttcc gtcgcgatac ggacgatgcg
      961 acccacagtc accaattcca ccaaatcgaa ggcttggtag ttgggaaaaa tatctctatg
     1021 gctgatcttc aaggaacgct tcagttgatt gtccaaaaaa tgtttggtga agagcgtcaa
     1081 attcgtttgc gtccatctta cttcccattc acagagccat ctgttgaggt ggatgtttct
     1141 tgcttcaagt gtggtggaga aggctgtaac gtatgtaaga aaacaggttg gatcgaaatt
     1201 atgggagccg gtatggttca cccacgtgtc cttgaaatga gtggtatcga tgcgactgta
     1261 tactctggtt ttgcctttgg tcttggacaa gagcgtgtag ctatgctccg ttatggaatc
     1321 aacgatatcc gtggattcta ccaaggagat gtccgcttct cagaacagtt taaataatga
     1381 ttagaaaagt agaaatggca gatgttgagg tgttggctaa aattgccaaa caagcctttc
     1441 gtgaaacctt tgcgtatgat aatacggaag agcagttaca ggaatacttt gaagaggctt
     1501 atagtctgaa aactttgtca actgagttgg gaaatcctga ctctgaaacc tatttcatta
     1561 tgcatgagga ggagatagct ggttttctca aagtcaactg gggaagtgct caaactgaga
     1621 gagaattaga ggacgctttt gaaattcaac gcctctatgt gctacaaaaa ttccaaggat
     1681 ttggactagg taagcaactg tttgaattcg cacttgaact tgctacaaaa aatagttttt
     1741 cttgggcttg gctaggtgtt tgggagcata atacaaaagc tcaagcgttt tataatcgat
     1801 atggttttga aaaatttagc caacatcatt ttatggttgg tcaaaaagta gatacggatt
     1861 ggttactgag aaagaaatta aggtaagaag aggattcttc tattgaaatg ataggaaagg
     1921 aaaagaacca gtgtggcaat ggtcattctg gagaactaaa ttatgcttat atcttataaa
     1981 tggttaaaag aattggtgga cattgatgtg ccatcacaag agttggctga aaaaatgtca
     2041 actacaggaa tcgaggtaga gggtgtcgaa tcaccagctg ctggtctctc aaaaattgtc
     2101 gtcggtgagg tcttgtcttg cgaagatgtg ccagagactc acctccatgt ttgtcaggtt
     2161 aacgttggcg aagaagagcg tcagatcgtt tgtggtgccc caaatgtgcg tgctgggatc
     2221 aaggtcatgg tggctcttcc aggagctcgt atcgctgata actacaaaat caaaaaagga
     2281 aaaatccgtg gtttggagtc acttggaatg atctgttcac ttggtgaatt gggaatttct
     2341 gactcagttg tgcctaagga attcgcagat ggcatccaaa tcttgcctga agatgccgtg
     2401 ccaggtgagg aagtcttttc ttacctagac ttggatgatg aaatcatcga actttccatc
     2461 acaccaaacc gtgcagatgc cctttctatg tgtggagtgg ctcacgaagt ggcagccatc
     2521 tatgacaagg cagtcaactt taaagaattt actctaacag aaactaatga agctgcggca
     2581 gatgcccttt ctgtcagcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     2641 gacaatgtga ccatcgcacc aagtccacaa tggttgcaaa atcttctcat gaacgaagga
     2701 atccgtccca tcaataacgt agtggacgtg accaactaca tcctgctcta ttttggtcaa
     2761 ccaatgcatg cctttgactt ggataacttt gaagggactg acatccgtgt gcgtgaagcg
     2821 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     2881 ctagtcatca ctgtcgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     2941 acagaaatct ctgaaaaatc tagtcgtgtt gtccttgaag ctgctgtttt caatggcaaa
     3001 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     3061 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg
     3121 gaacttgcag gtgcgacggt gcgtaagggc atcgtttcag cgggtgagct tgatacttca
     3181 gatgtagaag tttcttcaac ccttgctgat gttaatcgtg tcctcggaac tgagctgtct
     3241 tatgctgatg tagaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     3301 agctttacag tcagagtccc acgtcgtcgt tgggatatca caatcgaagc tgacctcttt
     3361 gaagaaattg ctcgtatcta tggttatgac cgcttgccaa ctagtctacc aaaagacgat
     3421 ggtacagcag gtgaattgac agccacacaa aaactccgcc gtcaagttcg tactattgct
     3481 gaaggagcag gtttgacaga aatcatcacc tatactctaa caactcctga aaaagcagtt
     3541 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     3601 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     3661 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     3721 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     3781 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taagggaatc
     3841 cttgaagccc tatttactcg tttgggactc caagtaacct atacagcaac atctgaaatc
     3901 gctagccttc atccaggtcg tacagccgtg atttcattcg gtgaccaagt tcttggtttc
     3961 cttggccaag tgcatccagt cactgccaag gcttacgata ttccagaaac gtatgtggct
     4021 gagcttaacc tttcagctat cgaagctgcg cttcagccag cgactccatt tgtagaaatc
     4081 accaaattcc cggcagtcag ccgtgacgtt gcccttctcc tcaaggcaga agtgactcat
     4141 caagaagttg tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     4201 tttgacgtct tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     4261 accttccaaa atccagaaga tagcttaacg gacgaagaag tcgcacgcta tatggaaaaa
     4321 atccaagcat cgctcgaaga aaaagtcaat gcagaagtgc gttaaacgat agtatgatac
     4381 aaattccccc tctagtttat gaacactaga ggggtgattt tatataaaat aattaaaatg
     4441 tgatttctgt aaaaatacat ctatgatcag agttttgaaa acttacaatg tctaaatctt
     4501 taacatagta gtggttttta ggcaataaaa tatgatctat tgttgcatta aaaagttttg
     4561 gactttggct attccaagtt cctctttcaa aaggtggcag tacatttaat gcgtccctat
     4621 gagagcttat ttttgcaagt gctccatgac gcatagttgc attaaaatca cctgcaataa
     4681 tagcctttgg atattttgaa gccaattgat tatgaatgat gtttaagtct tgcttccaga
     4741 tttccattaa acctggcaga ggaggagcag tatgcaaggc aatgatatct ggtatatttt
     4801 gttttctcga atgtaataca attgtcccga accgtgttgt atgaaaagtt ttagcttctg
     4861 tatagaaacc ataacttttc ttgacaatca cagtcacagg agctattcca ctattggtag
     4921 gtggagaagt gaaaatatca tagttggcca tagaaagtcc aacttgatga aacaatagtt
     4981 tgattctctg gttttcttgc tcacctctga tattggtagc tagttcaggg aatatagcca
     5041 tatcggcgtc aaaatggcta aaaattcgct caatatgttg tgcttctatt tgattagcga
     5101 cgttccaagt tactaatttt aaggttttag tcttatttga tgcagaagaa agggttttat
     5161 ctgttccgaa taatagtaat atgagcgata gtaagagcaa aatgccagag taaaaccgta
     5221 tttgtttatt tttcttgtaa aaagataggg aaaaaaatac gaaacttaaa atagcagcca
     5281 tagttgcagt agctaagggg aaggcataaa tctgtgccaa gataggttgg gtagatagcc
     5341 aaatgttaag attagaagat gggaaaaaag aataagttat aatagggata gaaaagagaa
     5401 tgaccgaaag ggcagagaga aatgttttaa tcattgtgtg agtacctcaa tttgcaatgg
     5461 ttgctcggag ctaatgtgac tttgtgactt tacttgattg atattctttt tcttgtcttc
     5521 ctcatagatt aagtacaacc caagtaaaaa aagtccaatt taagattgaa atgattaaaa
     5581 ggcacagaaa tgcaagacaa ttatactaca aaaggcaaac atttgacaat cgatagccgt
     5641 cgcttaatcg aacgatggaa aaaagaagga aaatcaaata gagaaattgc ctctctactt
     5701 ggaaaagctc ctcaaactat ccatactgaa atcaagtatg ggacagtccg acaatgtctt
     5761 ggaaaagggc gcttcaaaga gatttattct gccgactacg ctcaacagtc ttatgaaaat
     5821 aatcgcaagc actcggtcaa gaaatcaagc ttgactaaga aactaaagga aaagattctc
     5881 cactatcata accaaaaatt ttcgcctgaa atgatggtga tggctaaagg ggttaacgtg
     5941 ggaatttcaa ccatttacta ttggattcat cgtggaaaat tggggttaag caagcaggat
     6001 ctgctttatc ctagaaaagg aaaagcgctt aagaaatagg ctagcaccaa ctttaaaccc
     6061 gctggtcaat ctatcgaatc ataattcgct cattttttta aaaatacata gacgtaaaaa
     6121 aaagagggtt aagtgatgaa gaatagtgct attgggagta attggaagga tgtccatctg
     6181 agctctttag caaggaggaa atccttgaaa gtgatatgcg agtggctatc atgagcgagt
     6241 tgattgaggc taggtatgaa caaggaatca gtcagaaaaa gctggaagaa gtcagtggaa
     6301 taagccagcc tgtcatagct aggatggaga caggagagag cagtcttcag ttggatacgg
     6361 tcttaaaagt tctaaccagt ctaggaaaga cactagcagt cgttccactt gaacagggga
     6421 aaagttgact agaatcagtt atagtctttt ctaataacag gtcatagtca cttataagaa
     6481 ttactaataa catgttttag tattctaatt ggaatatagc tgtaaagtaa gaattacaaa
     6541 ggatttgaga cgtttgcttc aagtcttttt cttttgtccg aaacagatat atagtttcaa
     6601 actatatcaa accctaattt tttacaatta tacagacgct ttcttttctg ttaagatagt
     6661 ttcaacaaca aattttggag gacacatcat gtcaactaca atcatcggtt tccctcgttt
     6721 gggcgaattc cgtgaattaa aatttacaac tgaaaaatac tttagaaaag aaatctcaga
     6781 agaagaactt ttagcagcag caaaagactt gcgtgctaaa cactggaaca ttgtcaaaga
     6841 aaaaggcatc actgaaattc catcaaatga cttttctcac tatgataact tcctagatgc
     6901 ggctttcctt ttcaacgtgg tgcctgcatc cgttcaaaac ttggacttgt ctgaccttga
     6961 gcgctacttc gctttgggac gtggttacca gggagaaaaa ggggacgttc gcgcccttcc
     7021 aatgaagaaa tggttcaaca ctaactacca ctacatcgtt cctaaatttg aaaaagacac
     7081 tcaagtaaaa ttggctggtc acaagatttt cgatgagttc caagaagcaa aagaacttgg
     7141 attgaacact cgtcctgttc ttgtaggtcc attcactttc cttcaattgt cagactttga
     7201 agaaggcgtg aaagcagacg acttcgtaga tagcttagtg gttgcttacc aagaagtttt
     7261 tgctaaattg gctgaacttg gtgcgactcg catccaattg gatgaagcgg ctcttgtaaa
     7321 agacttgaca gctgaagaaa aagctctctt cttgaacctt tacaacaaac tcttggctga
     7381 caaaaaaggt cttgaagtct tgcttcaaac ttatttcggt gatgttcgtg acgtatacgc
     7441 tgaccttgta aacttgccag tagatgctat cggtcttgac tttgttgaag gtaagaaaac
     7501 tcttgaactc gttaaaggtg gcttcccagc tgacaagact ctctatgtag gtattgtcaa
     7561 tggtaaaaac atctggcgca acaactacga aaagagcttg gctgttcttg agcaaatccc
     7621 agctgaaaac atcgttttga caagctcttg ctcacttctt catgtgccat ttacaactgc
     7681 taatgaagaa tttgaaccag cactcttgaa ccactttgcc tttgcagttg aaaaattgga
     7741 tgaaatccgt gacttggatg ctatccgcaa tggtcaaggt tcagaagctc ttgcagccaa
     7801 caaagaactc tttgcgactg agcgtgttgg tgaaaatgct gaacttcgtg cgcgtatcgc
     7861 tggcttgaca gacgcagact acactcgttt gccagccttt gcagaacgtg aagctatcca
     7921 agaagaagct ttcaaacttc cagctcttcc aacaacaacg attggttcat tccctcaaac
     7981 aaaagaagtt cgtgccaaac gtttggctta ccgtaaaggt gaattgtctc aaaaagagta
     8041 cgatgctttc cttgctgaaa cgattgacga atggatcaag tggcaagaag atattgactt
     8101 tgatgtcctt gttcacggtg aatttgagcg taatgacatg gttgagtact tcggtcaaaa
     8161 cttgtcagga tacctcttct ctaaaaatgg atgggtacaa tcatacggta tgcgtggggt
     8221 aaaaccacca atcatctggg gtgatgtcac tcgtcttaac tctatcactg ttaaatggtc
     8281 tagctatgca caaagtcgta caaacaaacc tgttaaaggt atgttgactg gacctgttac
     8341 catccttaac tggtcattcc cacgtgaaga catctctatc aaggattcaa ctcttcaaat
     8401 cgcccttgct atcaaggatg aagtacttga ccttgaagct gctggtgtga aaatcatcca
     8461 aatcgacgag gctgctcttc gtgaaaaatt gccactccgc cgtagcgact ggtacgaaga
     8521 ctaccttgac tgggctattc ctgccttccg cttggtacac tcaacagtag cgccagacac
     8581 acaaatccac actcacatgt gttactcaga atttacagat atcatcccag ctatcgataa
     8641 catggatgca gacgttattt cctttgaagc tagccgttca aaccttgaaa tcttggacga
     8701 actcaaagcg aaaaacttcc aaacagaagt gggacctggg gtttacgata tccactcacc
     8761 tcgtgtacca aatgaaggcg aaatcgacaa cacaatcgaa gccatccttg ctaaagtgcc
     8821 aagcaagaaa gtttggatca accctgactg tggtttgaaa acacgtggta tcccagaaac
     8881 aaaagaaagc ttgatccgcc ttgttgaagc agctaaagct gcgcgtgaga aattgtaaga
     8941 ttggatttct ctccatacag tggttgttca aaaagaaatc aactagaaaa ggttattaca
     9001 tatgtcacgc caaacaccgt cactctcatt tgaagtgttc cctccaaacc cagccgtggg
     9061 taatggtaac attatttcag ccttgcagga tatgcaggag ttggctcccc attttatcag
     9121 tgtaactgcc agcaataata aatttaatat caaggaaacg acggttcgtt tggctgactt
     9181 tatccaaaat gacttggcga ttccgaccat tgcccacttg ccagctattt atctaactaa
     9241 ggacaaggtt gctgaaacta ttgctgactt ggacaaagtt ggggtgcaga aaatcttggc
     9301 tcttcgtggg gatattattc cagacgtaga accacaaaag gatttccgct atgcaaccga
     9361 cttgattgag tttatcaagg aacaagcccc tcactttgat attattggag cttgctatcc
     9421 agaagggcat ccagattcgc caaatcagat ttcagatatt caaaatctta agaagaaagt
     9481 ggatgcaggc tgttcgagcc tcgtaactca gctcttcttt gataatgagc gcttctatga
     9541 ttttcaggac aagtgtattt tggctgggat tgatgttccc attcatgcag gaattatgcc
     9601 aattctgaat cgaaatcagg ctctccgact cttgaagact tgtgagaata tccatcttcc
     9661 acgcaaattt aaagccatct tagacaagta tgagcatgac cctgagtcgc tcagagcagc
     9721 aggacttgcc tatgcagtgg accaaatcgt ggacttggta actcaggatg ttgccggtgt
     9781 gcatctctat acgatgaata atgctgatac agcaaaatac atccatcaag caacccatgc
     9841 cttgtttaat caccagtctc taggataata aaagcaaacc attcttctca ggtgagggga
     9901 atggttcctt tttaatggta aagacctcac tttttaagaa aaatatgata aaataaattc
     9961 tgtacgtact tgatacaaag atgaaggtat taaataatac aatgcattta aactgtaaga
    10021 tttaacgaca cgagtgagtc aaatcgatgt tatttgacga gagagttagt aaagcattta
    10081 gctaatcgcc cgatagcgat tagcgtgaaa gctttagata ctttagtatt aaacctttct
    10141 aatgatgtat cttgaaaact gaacttgcct acaactctgt ggaaaaagat aaatctccct
    10201 aggagcagtc gctccgtcgt tcgatttcct attttccttt gagttgcttg acggcttggt
    10261 atcttgatga cttgaatttt ggtctcattt cttaggaaaa aagataagct tcctagcact
    10321 cgtcgagtgc gacgtcacct tcctattttt ctacagaaat gttcggcaag ccgaaccgtc
    10381 caaaatatct tgtgtaattg aacacggccg aaaagctgtg taaaaaagat aaactgtctt
    10441 gtcttcatcg aagacttcgt cagtttccta tttttacttt gcttttgacg tccttggtat
    10501 cttgatcttt gtaggcaagg cgtataattt catcaatcca aaggggatta aaatggcaaa
    10561 acaagtgttt caaacgactt ttgcgggtcg tgagttaatt gtagaaactg gtcaggttgc
    10621 taagcaagca aatggctctg ttgtcgtacg ttacggtgag tcaactgtct tgactgctgc
    10681 cgttatgtct aagaaaatgg caactgggga tttcttccca ctccaagtca actacgaaga
    10741 aaaaatgtat gcggctggga agtttcctgg tggctttatg aaacgtgaag gacgtccttc
    10801 aacagatgcg accttgacag cgcgtttgat tgaccgtccg attcgtccta tgtttgcgga
    10861 aggtttccgt aatgaagtcc aagtcatcaa tacagtgctt tcttatgatg aaaatgcatc
    10921 tgcaccaatg gctgctatgt ttggttcatc tttggcactg tctatttcag atattccatt
    10981 tgacggacca attgctgggg tacaagtggg atatgtagat ggccaaatca tcatcaaccc
    11041 aagtcaagaa caagcagagc aatctcttct tgaattgaca gtagctggaa ccaagcacgc
    11101 tatcaacatg gtagagtctg gtgccaaaga attgtcagaa gaaatcatgt tggaagcgct
    11161 tcttaaaggg cacgaagctg tcaaagaatt gattgccttc caagaagaaa tcgttgctgc
    11221 tgtcggtaaa gaaaaagcag aagtggaatt gcttcacgtg gatgctgaat tgcaagctga
    11281 aatcattgca gcctacaaca gtgacctcca aaaggcagtt caagtagaag agaaattggc
    11341 ccgtgaagct gcaactcaag cagtgaaaga ccaagtgact gccgtttacg aagaaaaata
    11401 tgcgaaccac gaagaatttg accgtattat gcgtgatgtg gctgaaatct tggaacaaat
    11461 ggaacacgca gaagtgcgac gtttaattac agaagacaag gtgcgtcctg atggtcgtaa
    11521 ggtcgatgaa atccgtcctt tggatgcggt tgttgacttc cttcctcgtg tacatggttc
    11581 aggtctcttt actcgtgggc aaactcaagc tctttcagtc ttgaccttgg ctccgatggg
    11641 agaaactcaa atcattgatg gtttggatcc agagtacaag aaacgcttta tgcaccacta
    11701 taacttccct caatattctg taggggaaac aggtcgttac ggtgcgccag gtcgtcgtga
    11761 aatcggtcac ggtgcccttg gtgagcgtgc tcttgctcaa gtcttgccaa gcttggaaga
    11821 attcccatac gctatccgtc tagtagcaga agttttggaa tcaaacggtt cttcatctca
    11881 agcttctatc tgtgcgggaa ctcttgccct tatgactggt ggtgtgccaa tcaaggcgcc
    11941 agtagctggt attgctatgg gacttatctc agatggaaat aactacacag tattgacaga
    12001 tatccaaggt ttggaagatc actttggaga tatggacttc aaggttgcag gtactcgtga
    12061 tgggattaca gcccttcaaa tggatatcaa gattcaaggg attactgcag aaatcttgac
    12121 ggaggctctt gctcaagcca agaaagcgcg ttttgaaatc cttgatgtca ttgaagcaac
    12181 cattccagaa gttcgtccag aattggctcc aactgctccg aaaattgata cgatcaagat
    12241 tgatgtggac aagattaaga ttgtcatcgg taagggtgga gaaaccatcg acaagattat
    12301 cgctgaaaca ggtgttaaga ttgatataga cgaagaagga aatgtgtcta tctactctag
    12361 tgaccaagat gctattaacc gtgccaaaga aattattgct ggtttggttc gtgaagccaa
    12421 agtggatgaa gtttaccgtg ctaaagtcgt tcgtatcgag aaatttggtg cctttgttaa
    12481 cctctttgat aagacagatg cccttgttca tatctctgag atggcttgga ctcgtaccaa
    12541 tcgtgtagag gatttggtag aaatcgggga tgaagttgat gttaaggtta tcaagattga
    12601 tgaaaaaggc cgtatcgatg cctctatgaa ggctcttcta cctcgtccgc caaaacctga
    12661 gcatgatgaa aaaggtgaaa agtctgagcg ccctcaccgc ccacgtcatc acaaggatca
    12721 caaacctaag aaagaattta cagaaacacc aaaagattca gagtaagaaa aggagaaatg
    12781 tatggggtgg tggcacgaaa ccattgatat cgtaaaagaa aatgatccag cggcccgcac
    12841 cactttggag gttttgctga cttatccagg tgtcaaggcc ttggcggccc accgtctctc
    12901 gcattttctc tggaagtacg acttcaaact cttagctcgt atgcacagtc agttttggcg
    12961 cttttggact cagattgaga ttcatccagg agcccagatt gattcaggtg tctttattga
    13021 ccatggttct ggtctggtga ttggagagac agcgattgtt gaaaaaggcg ttcttctcta
    13081 tcacggagtg actctcgggg gaacagggaa agactgtggc aaacgccatc cgactgtacg
    13141 aaagggagcc ctcatatcag cccatgccca agttatcggg cctgtggaaa ttggtgaaaa
    13201 tgccaaggtc ggtgctgcag cagttgtcgt agcagatgta cctagtgatg tgacggttgt
    13261 cggtattccg gccaagattg tccgtcttca tggtaagaaa gatgagcctg ttattcacga
    13321 agtcgaagaa aaacgggagt attatgtcaa taaactcgag caggctaaag atgccagtca
    13381 cagatcgtct ggtttgtaga ggatacctat atgattcaag caagaaacaa gttaagccaa
    13441 gaggagctat ctgaggcgaa aaaagtaatt aactgttgcc aaaactatga cggtacctat
    13501 cgcgatccct atctctctaa catgcttaat tttgacccaa acatgcccgc ctttttcctt
    13561 tattatgaaa aaggcaaact tgttggttta ttaactgtct atgcagatga ccaagatgta
    13621 gaagtgacga tattggttca tccaggtcat cgccgtcagg ggattgcgcg tgcattgttt
    13681 actagttttg agagagaaac agcttctttc cccattcggt cagtcacttt tcagacagaa
    13741 cgtatttttt tagagaatca tcctgacttt gccagtaact ggggactaat cgaggatgaa
    13801 gagacagaaa cttggttagg taaggataga agaccttatc cgttagcaaa tgtttcccat
    13861 cttgaagttt tgttagcaga tagttcgtat caggatcaaa ttagtcaatt aaaatttcag
    13921 gcattttcag aggaacatga atcgagagaa gttgtggata gatatgtcgc tgaagctctg
    13981 aaggatccag aaagtcgctt atatattttg ttaaaagacg gtcaggttat tgggacttgc
    14041 acggtagatt tatcgactaa tacgaattac ttctacggtt tagcaatatc ggaacctgaa
    14101 cgtgggaaag gctatggaag ctacttagca aaatccctcg tcaaccaact aattgagcaa
    14161 aatgacaagg aatttcagat tgcagtggaa gatagcaatg taggtgccaa acgtttgtat
    14221 gaaaaaattg gctttgtcaa acagacacag gtggtttatc tgaatgagaa aggagcaagg
    14281 gattccgaag tgtagagaca ttcggactga aatttacttg agctcttagt ttagtgatga
    14341 aactaacagt tcttggattt tagctttcct gattatgatt tatgattaaa atctatgaca
    14401 ccatgtctcg tgatttgcga gaatttgtcc cgattgagga cggcaagatc aagatgtatg
    14461 tttgtgggcc aaccgtgtac aactatattc acgtgggaaa cgcccgttcg acggtagctt
    14521 ttgatacgat tcgtcgctat tttgagtacc gtgggtataa ggttgcctat atttccaatt
    14581 ttacagatgt ggatgataag attatcaacc gtgccaggga agaaggcatc acacctcagg
    14641 aggttgcgga taagtacatc gctgcctttc gtgaggatgt gacggcctta ggcgtgaaac
    14701 ctgcgactcg ccatccgcgt gtagtggagt ttatggcaga catcatccgt tttgtggaag
    14761 acttgatcga gaaaggcttt gcctatgaga gtcaagggga tgtctatttc cgtgtagaaa
    14821 aatcccacaa ctatgctaaa ttggctaata aaaccttgga agatttggag ctaggtgctt
    14881 caggtcgtac cgatgaagaa acggctcgta aggaaaatcc tgtagacttt gctctatgga
    14941 aatcttccaa accaggtgag atttcttggg atagtccttg gggacctgga cgtccgggtt
    15001 ggcatattga gtgttcagtc atgtcgacag agattttagg tgataccatt gatatccacg
    15061 gtggtggagc tgacctagag tttccacacc acaccaatga aattgcccaa tctgaagcta
    15121 aaacaggcaa ggcttttgct aactactgga tgcacaatgg ctttgtcaat atcgacaatg
    15181 tcaaaatgtc taagtccttg ggtaacttca ttacggtaca cgatgccctt aaaactcttg
    15241 atgggcaagt acttcgtttc ttctttgcga cccagcacta ccgtaagcct atcaacttca
    15301 cggaaaaggc agttcgcgat gccgagacca atctcaagta tctgaagaat acttacgaac
    15361 aaccatttac aggaaacgtg gatgcccaag agttacaaaa ctttaaagat aagtttgtag
    15421 cagctatgga tgaagatttt aatgctgcca acggtatcac agttgtcttt gaaatggcca
    15481 aatggatcaa ctcagggaac tatgatgcaa gtgtcaagca agctcttgca gatatgttag
    15541 aaatttttgg aattgtcttt gttgaggaag ttttggatgc agagattgaa gacttgattc
    15601 aaaaacgcca agaggcgcgt gccaatcgtg actttgagac agcagaccaa atccgtgacc
    15661 aattggttac tcaaggaatt aagctccttg ataccaagga tggagtgagg tggacacgtg
    15721 attgatgtca atctcattaa cgggattgcg ctagcctttg agggagatgc ggtgtattct
    15781 atgtatattc gccgccacct catcctcaaa ggtatgacca agcccaataa actccaccaa
    15841 gaggcgacca agtacgtgtc agccaaggct caggctcgtc tgattgctct catgttggag
    15901 gagcagatcc taacggaaaa agaagaagaa atctacaaac gtggccgcaa taccaatagt
    15961 cacacaaagg ctaaaaatgc agatgtcgtg acttatcgta tgtccacggg atttgaagca
    16021 gttatgggct atctccatat gactgagaat ctggaacgtc ttgagagttt ggtttcatgg
    16081 tgcatccaaa aagtggaggg ctagaacatg agggcaaaag aactacaaga ctggtttcct
    16141 gaggctcgga tttcagacca accagtagag aaagagggct atctcacgct tcctttagct
    16201 tctcagcagt ggattttgct ggaggaagct gggctcagcg agcgtgaaaa gcagttggtt
    16261 gcccttttga cccagcagga gcaggctcgt tcgctaaacc cttggtattc ctatctggtt
    16321 gagggcaagg gacaggcacc gcaagttttt aaaaagattc agttggttta ttgccatctt
    16381 tcttattttc agcaggaaaa tctgacttct tggctagata tgatgcggac tctttttccg
    16441 aattgtcaga cagtgctaca ggtcggagct caggattatg ttttcgtgct tcaacaagac
    16501 aaatacactt ctgtaagaga tattttgagt gatacgattg aagcggttga gtatgacttt
    16561 ggacttcgtc tttctatcat gttgggtcag gtttggtctc agacaggaca tcaagcccta
    16621 tcagacttaa tcaaagctga gcgggatttg ttcaagacat ggtggcgtca gggtcaccaa
    16681 ggtgttcata ctttttctca gctctatctt tggagtatgg gagaaagact cgtggacttg
    16741 aagccaatta aagaatgtct acaccagatg attttggatc aagatcagat tcaggaaatc
    16801 attctctctc tttgggaaaa tagtgctgtt ctcactaaaa cagcccagca actctatctg
    16861 caccgcaatt ctctccaata caagattgat aaatgggaag agttgacagg gcttcagttg
    16921 aaagagttga ccgacctgac cttgtgttat caattgattt taggttcttt gtcaactata
    16981 gttggtttgt aaagaagtta atatggctct ttgtcaactg tagtgggttg aaaaaaagct
    17041 aagctcgaga aaggacaaat tttgtccttt cttttttgat attcagagcg ataaaaatcc
    17101 gttttttgaa gttttcaaag tttcgaaaac caaaggcatt gcgtttgata agtttgatga
    17161 gattattggt cgcttccaat ttggcgtttg aatagggtag ttgaagggcg ttgacgattt
    17221 tctttttgtc ctttagaaag gttttaaaga cagtctgaaa aagaggatga acctgcttaa
    17281 gattgtcctc aataagtccg aaaaatttct ctggttcctt attctgaaag tgaaacagca
    17341 agagttgata gagctgatag tgatgtttca agtcttgtga atagctcaaa agcttgtcta
    17401 aaatctcttt attggttaaa tgcatacgaa aagtagggcg ataaaaatgt ttatcgctga
    17461 gtttacg
//
LOCUS       DAVLCS010000040        16506 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLCS010000040 DAVLCS010000000
VERSION     DAVLCS010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.040"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(<1..885)
                     /gene="phtB"
                     /locus_tag="VXC78_001653"
     CDS             complement(<1..885)
                     /gene="phtB"
                     /locus_tag="VXC78_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV0583687.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGL"
     gene            complement(893..1810)
                     /gene="adcAII"
                     /locus_tag="VXC78_001654"
     CDS             complement(893..1810)
                     /gene="adcAII"
                     /locus_tag="VXC78_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV0583688.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDREHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            complement(1953..3344)
                     /locus_tag="VXC78_001655"
     CDS             complement(1953..3344)
                     /locus_tag="VXC78_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV0583689.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            complement(3718..4275)
                     /gene="sdbB"
                     /locus_tag="VXC78_001656"
     CDS             complement(3718..4275)
                     /gene="sdbB"
                     /locus_tag="VXC78_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV0583690.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDDKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            complement(4286..4993)
                     /gene="ccdA2"
                     /locus_tag="VXC78_001657"
     CDS             complement(4286..4993)
                     /gene="ccdA2"
                     /locus_tag="VXC78_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0583691.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            complement(5224..5640)
                     /locus_tag="VXC78_001658"
     CDS             complement(5224..5640)
                     /locus_tag="VXC78_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583692.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            complement(5665..5865)
                     /locus_tag="VXC78_001659"
                     /pseudo
     CDS             complement(5665..5865)
                     /locus_tag="VXC78_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6020..6678)
                     /locus_tag="VXC78_001660"
                     /pseudo
     CDS             complement(6020..6678)
                     /locus_tag="VXC78_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(6892..8655)
                     /locus_tag="VXC78_001661"
     CDS             complement(6892..8655)
                     /locus_tag="VXC78_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV0583693.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINFLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFEFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASFFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            complement(8664..9254)
                     /locus_tag="VXC78_001662"
     CDS             complement(8664..9254)
                     /locus_tag="VXC78_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV0583694.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            complement(9352..9843)
                     /gene="rocS"
                     /locus_tag="VXC78_001663"
     CDS             complement(9352..9843)
                     /gene="rocS"
                     /locus_tag="VXC78_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV0583695.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            complement(9920..10612)
                     /locus_tag="VXC78_001664"
     CDS             complement(9920..10612)
                     /locus_tag="VXC78_001664"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV0583696.1"
                     /translation="MKIGIIAAMPEELAYLVQHLYNVQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHTLNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            complement(10629..10943)
                     /locus_tag="VXC78_001665"
     CDS             complement(10629..10943)
                     /locus_tag="VXC78_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV0583697.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKNHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            complement(10955..11500)
                     /locus_tag="VXC78_001666"
     CDS             complement(10955..11500)
                     /locus_tag="VXC78_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0583698.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            complement(11510..12889)
                     /gene="glmU"
                     /locus_tag="VXC78_001667"
     CDS             complement(11510..12889)
                     /gene="glmU"
                     /locus_tag="VXC78_001667"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV0583699.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            13033..13833
                     /locus_tag="VXC78_001668"
     CDS             13033..13833
                     /locus_tag="VXC78_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV0583700.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            13928..14770
                     /locus_tag="VXC78_001669"
     CDS             13928..14770
                     /locus_tag="VXC78_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV0583701.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGALAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLTWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            14770..15252
                     /locus_tag="VXC78_001670"
     CDS             14770..15252
                     /locus_tag="VXC78_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV0583702.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            15252..15872
                     /locus_tag="VXC78_001671"
     CDS             15252..15872
                     /locus_tag="VXC78_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0583703.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(16126..16221)
                     /locus_tag="VXC78_001672"
                     /pseudo
     CDS             complement(16126..16221)
                     /locus_tag="VXC78_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5006 a         3485 c         2895 g         5120 t
ORIGIN      
        1 aaggccatca gattccacat ggcgttctga taagggttta gcatacaatt cacgtaaaag
       61 gcttgaaatg ttttcccctt gattttgatg ataagttgga gtgacagtca gattgtggtt
      121 ctctgacaat cttggttgag ctggatttgc attataacta gaacttgaag aaggacgaga
      181 tccctgcttc ccattccaat aggcttctgc agcagctaac tcgctagctg ataactcatt
      241 cttaggaatg taatggtaat ggtcgccgtg aggaacgata taagcatcac ccgtgtcctc
      301 aatgatatca gatgcattga agatataccc atcatccgtt gtataacgtc cttgggctct
      361 ggctgcagca acagcattat ctgctcttga gttatgatta tgactgcgtt cctgcttctg
      421 acgtttaatc tcttcttttg tccgaatatt atccgcatga gctgcatcct taaggtaaac
      481 atagtattta ccgtttacct taatgacata accacccttg atttcattga caatgtctga
      541 atccttcaac tgataattcg gatctttcat gaggagctct tcactgatga tggcatcata
      601 aggaaccttg ccattatagt aatgataatg gtctccatga gaggtcacat aaccttgatc
      661 cgtaatcttg ataacaattt gttcggcgtt gatcccctcc ctcttactga cttcatctgg
      721 tgtcaagttt tctgcctttt gaccagcctg atcaccatct atataagcaa ctcgattaga
      781 ctctttctta tcctgaccag cttggtaacg tccaagctca taggaacaaa cacttagggc
      841 aaggactgcc actgaacctg ctagatattt tttattaatt ttcattcttt cctcacttta
      901 attcttctgc tagaatactc atattttctt caagattttc taaataggtc ttgtcatttt
      961 gtgggtctga ctctaaagga ttcagagttt taagacccac acctgttgat ttgacaagag
     1021 tttcagctac ttttgaagaa gcgttacttt ctgtaaaaat cgttttaacc ttataggtct
     1081 taacaaattc ctgaatttct gttagttgtc gtggacttgg ttcttgttca ggagagatac
     1141 ctgcaatacc aagttgatta agcccaaatc tcttcgctag ataagaaaag gctgtatgtt
     1201 gtgttacaaa tgttttctga gtcgcttttt caaattttgg ttggaatttc ttagtcaatt
     1261 cctgagcttt tttgataaag gcttgcgcat ttttttgata agtctcttta tgctccctat
     1321 ccacctctga aagtttatca gcgataattt gggcttcttc tccagctttt tcaggatcta
     1381 gccatgtgtg agggtcatag agcgtttttt catcaactcc atcccctgct tccacatcct
     1441 ctagtccagg gacacgttcc aaggtcattc cctcagaagc ctctaagacc ttcactttgg
     1501 atttttttag atttggatcc agacttcctg cccaagattc gagtgtatga gaatggtaaa
     1561 caaagacatc tgcatcatag atggctgcga tatcatttgc cgaaggttca aaggagtgaa
     1621 taccactact tgactgaatc atccgaacat cattcaagtc accagatact tccttaacca
     1681 tagcgtagat aggataaaaa ctggtcacaa ttttcatccc ctttcctgtc tgactttcct
     1741 tttgaccaca agcccccaag cacaaaagaa agacacttaa caggactaaa aataaatttt
     1801 gtttcttcat gaacaactcc ttaaccattt aattaactag taaatattct actcctgaaa
     1861 atttaatctg tcaagatatt tttagaaaaa atttgaaatt tctttcacat ataaaaatct
     1921 actgagtgtc aacaactcaa tagactttca ctttattctt ctatggtaga atgcttatag
     1981 ccataagtga agtaaataat acttcctact aacaacgcaa ctaggaaagc aatccaggta
     2041 ttcatattat actgtaacat gaaggataaa caaatgatga tcgataaaat tggtaacaga
     2101 ggtaccaatg gtgttttaaa ttccccagct ttgggcattc ctttttcttt ccgtaagcga
     2161 atcagaccat aagccaacat gatcaagtag gctaaggtac aaatatttaa aaaggctgca
     2221 atactggcta gtgggaacat tcctgctgct actgctgaag ctagacctgt caagatagta
     2281 gcattctttg gtatcttgct agtcttcgtc agttccttaa aggcagcagg cactaagccg
     2341 tcacgtgcta aactgtaaat catacgcgat agggcatagg tcatcgaaat acaaactgta
     2401 atcaaggtca agatagccac taatgacaca tagttggctg cccaactaat cccaacacta
     2461 cgaagggcaa aggcaacggc atcatcgaca tttaaatgac tatagtgaac cacaccagtc
     2521 aaaacaaggg tcaccaaggc atagagaatg gttacgatag aaagcgataa gacaatccct
     2581 ctaggaatat ttttttgagg agtcttgact tcatctacag ccatagagat ggattcaaat
     2641 cccaaaaaac cgaagaacat caaggatgca ccagccataa taccagtact agctccatag
     2701 atttgtccaa aaccgtaagg agcaaaattg ctccaattat caaacttaat attccaaatt
     2761 cctactaaaa caaagagagc taaagcggaa aatttcaaaa taactagaat cgaattaaag
     2821 cgtaaggctg ccttggcatt tagtaaaaca agcgaagtca ccaagaccaa gacaagaata
     2881 ggcaataaat caacaaatgt ccctgcttga ggattaaagg taccatttaa agcctgagga
     2941 aaggctatcc cgtattgaga gagcaagcct ttaaaataag ctgcccaacc cgaagctacg
     3001 cctgatatgg ctgtcatgaa ctccatcatg gttaaccaac cagccaacca ggcagggaat
     3061 tctcctaaga tagcatagag gtaactatag gcacctcctg tagcgggtac tcgcgaggca
     3121 aattctgcaa aaaagagggc tgataatccc acacacaagg cagaaataac gattgaaatc
     3181 actagggctg ggccagcaag tgttgcagct gcagtacctg tgattgtaaa gacgcctgtc
     3241 cctaccatgg ctccgatacc cagcaaaatc aaatcccata acttcaaatg cctatgcatc
     3301 tctgttttat ctaaactaac attctttgtt ctaaatatat tcatctttga ctccaaaata
     3361 aactgataat tctattttac cataaatata ggagatatgt gaatatttat aaaatgtttt
     3421 tctaaaaaaa tctgactacc gtaacttctc aaagtaactt ccatctctct cccaaaactg
     3481 gaagttactc taagacgact ctgttttagg gctatttgtc gtgcactttt tctgagtctt
     3541 ttcgcttttg aacccttata tatcaagaaa aagaaaacca gtggaagtta gtctaagacg
     3601 gatttccact gatgtcacgc gtttttctca tactaaaagc taggttgtgg gaaactggaa
     3661 gttagtttta gaagttacca aaatctgact acatcttgta atcagatttt atcgattcta
     3721 gttcatttct ttaaatgctg cttctgcatc cgcattactg atagcaccaa attgaatctt
     3781 tccaatcttt ccttggctat caattaaata ttctgtagga atgcttcgaa tttgataagc
     3841 ttggaaggtg gttgctttgg tatcataaag aactgggata tccttatatc cttgttcctg
     3901 gaaccattgt gggaattgct caacagtttt ttcaccttga attcctggtg caatgacagt
     3961 aagaatttcg aaatcacgat ctggtttcgc cgctagttcc atcaactctg gcatactttt
     4021 cttgcatgga ccacaccatg aagcccaaaa cttcaagtaa acctttttac ccttaaaatc
     4081 agataactta acttctttgt catccatgga ttgcaatgta aagtctggag catcttttcc
     4141 aacagaaatt tgttgtacag tcgtttgttg ttttggctgt tgtgctgctt gagtcttttt
     4201 agtttcttcc tcaccacagg ccatcaatac aactaatgac aagagactta agccagcaaa
     4261 cattactttt ttcatttgtc ctcctttatt caaaaattcc agctagaaca tttacttgtc
     4321 ctaatagtaa caaaattccc attaaaacga tgaggaaacc accaattttc tttagtagca
     4381 tcatatgacg cttgatttta ctaaaatatg gcatgactag acctgaagct agtgccaaga
     4441 ccaagaaagg aagggccatg cccagagtgt aaatgagagt ataaatcgct ccttgccaag
     4501 caccattgcc tccagaagcc gcaagtgcta aaacagaact taaaactgga ccaatacaag
     4561 gtgtccaacc aaagctaaag gtaataccaa gtaaaaaagc tgaccaataa cgattagaat
     4621 ctgatttttt aaaggtaaaa cttttttgaa cttctaattt cttcaaatga aaaatttcca
     4681 tctggtgaag acccaaaatg ataataatag ctcccatgac atatcgaaac caatttgcat
     4741 agagaatatg accaaagtaa ccagcaccaa agcctagaat aaagaaaatg agagagatac
     4801 cagcgataaa gcaaagtgtt cgaatcaagc ctgaccagag aacctttctc ccaaacaaag
     4861 aaaagctttt tgcactttct tgatcatcca ataaaatccc agcatagact ggcagaagag
     4921 gaaaaataca aggagaaaaa aaggataaaa cacctgctag aaaaacagag attaaaaata
     4981 ctatcgtttc caataaagaa ccaactttct taataattct aatcctattt tactatattc
     5041 aattttattt gtaagctttc tgctacgcaa aatcgtatcg ggcactattg gaccaatctt
     5101 ttcttttgct agtcaaggcg gatcttatcc cccaaaatag ccaaaaagca acgacaagga
     5161 ttactcgtca ctgcttttgt gaacgaaaat gtcttttagg tctgacattt cataaatcat
     5221 gttttacttg agtttgtcaa ggattgcttt aagctcctct actagtttag tttctgtctc
     5281 tgctgagcca ttttcttctt tcacgaaatc aagggtttct tggagaaggt tttgggcttt
     5341 ggcaaggact tttttatccg ctttttctgc atctagctgt cctagaacct tgatcaattc
     5401 cgtgcttaat tgctggattt ctgactcttt cttacggcga atcagccaga aggcaatcac
     5461 gcctaggagg gcaagtagac tgaccacaat cactcctgcc ggaactgagt ttgtttcagt
     5521 catcttatct gaatccttac tatcttccgt tccttgtttt gcatccttct tgtcctgtgc
     5581 aggcttgctg tcgctagcat ttgctttcac atctttgaga gagtccaagg cagccttcac
     5641 agactctact gcagtatgca gaccttactc tgtcaaggca ctatcttccg gagctttttg
     5701 agcatctagg aggacagcct tggttgcatc gattttcgga tcagatactg ttgccaaagc
     5761 tttcaagcgt tggtctaact cttgactcaa ggcacgaagt tcagacttgt caacttactc
     5821 ttgagcttgt gtgctcgttg agctagccga agcgcttact accactctag gatcttgagt
     5881 cggagctgag cttggagctg gggcaggact tgcaggttga ctaggagcag ttatggtata
     5941 ttgaaactag aatagtacat atggacttct aaaacattgt tagaattcga ttttactgtc
     6001 ctgatcgatt tgtcctattc ttatttcgtt ttactataat aaccgatggt gtggttaatg
     6061 ttggtaagag aaacttctga aaccaagctt caaaaaagtc gctcgtcatc gtctcttcgt
     6121 aagccattgg agcgattaac tcaccattca tttgttagac ctgcaaccaa agaaatcctc
     6181 tgatatcttc ttccagatac tttgcctctt attaactgac tttttaatga gcgaccatat
     6241 tctcgataaa aataagtatc gaatcctgtt tcatcaatct aaacaggtgc taggtgcttt
     6301 aatctattaa aattcttaag aaataaggct actttttctg ggtcttgttc atagtaggtg
     6361 tggttctttt tttcgagtgt agcccatagc tttgagcgca tagtggatgg tagttggatg
     6421 acagccaaat tcagaagcta tttcagtcaa ataagcatct ggattgtcag taagatagtt
     6481 tttaagtcta tctctatcaa cttttcttgg ttttgttcct tttacttggt ggtttagctc
     6541 tcctgttttc tcttttagct ttaaccagcc ataaatggta ttacgtgaga tttggaaaac
     6601 gtgtgatgct tctgttatac tacctgttcg ctcacaataa gagagaactt ttttacgaaa
     6661 atctattgaa tatgccataa gaagattata ccacattgtg tactattttt ggttcatttt
     6721 actatatttt agaagttata gtgtagcatt ccaacttcaa agcactataa agtaaattga
     6781 aacaagaaca atacaaacaa ttctcgtaaa cggattgcaa ccacaaaaaa gcaagcattc
     6841 acaagaatac ttacctatca tgggaggaac aaccgttcct cttttttatt actaaaattc
     6901 aaagaattcc aatgcttttt tcaagagcaa atccgtatat tctggatctt cttgggctac
     6961 ttctatttcc cgctgaactt tttccaaatc atctgtaatc actccatcta ctcctaagtg
     7021 aagagatttg ctgatagctt ctgaatcatt gacagtccag acataaagtt tctgatccgt
     7081 tgtccatagt ttgcttacaa aatattcatc caaggttgag tactccatag tatatcctgt
     7141 cgctcttgtt ttaggaaaga cagaattgta gggcatgatg aaataaactg gcagttcggc
     7201 atcatactgt cttacttttt cgacaacatg gtagtctaaa gactggattt gatgtccata
     7261 aatcttgagc tttgcagcat aacgggctaa aaagcggttc atcatgtctg gactatcttt
     7321 tttactggtt ttaatttcaa ttagtaattt ttgaccaagt tcgttggctc gactgagata
     7381 atcttcaaag cttgaaattt tagtctggta gccattttca aaaatatcaa tccctttaag
     7441 ctcctccaag tttaagtctt gaggactttt attgatacct gctagatttt tcaagttagc
     7501 atcatgcatc atgacaaact gcccatcttt tgtttcctgc acgtccgtct ccaccaagtc
     7561 tggtttgagt tgtgctgtag tttccaagga ctctactgta ttttgaatcc catttgcatt
     7621 ggaaacccct cggtgagaaa taagttgagg tagatgaacc atgggagcct ccagataaat
     7681 ataaccttct aaggcaaaga aaaaactggc acaagtcatg acaccccatc gcacgatgtg
     7741 atctttttct ctcctaggaa gcatatccag ctcctttcct gtcaaaaatg aaacaaattt
     7801 aaccaaaaaa taagtcagag ccatataata gagattttta atcacgacaa aattcaaaat
     7861 accaagaatc agagactctc tctgagtgat atcatctacc aaagtttgag ccaataataa
     7921 aggaatcaaa ggaagataaa ataataaatg tgctttgagc aagatgtaaa ataaattcca
     7981 agcataaaaa gtaactctct tcttggtttt ctccaagcta aacatcactg cttctcgaac
     8041 agtcagctga tcatatacaa tcttcggaag ggcaaacatc aatctgacag agacatagag
     8101 aaagataaga gatagaagta ggatgctcag ccaccacatc caatatttat cttctaaata
     8161 agcttggata aactctggaa tgacgatttt attaagataa taaatcttca gcattttccg
     8221 tataaaagga aacagcatag ctatatagaa aaagataaac aaggctttag cgccagttag
     8281 ctttttcata aattcaaaac tttcatggaa aaccttgcgg atatactcaa ttagccttcg
     8341 cttttcatta tagaggagat gacgagcacc aataaagagg agtcctattt gaaaataagc
     8401 aaccagaaag ttaattacaa tcaaggctaa aaaagctaga ctaatcaatg gagaatgagt
     8461 aaggatggct aagacattgt tataggaaat aaaaagataa cctgtctgat ctaataagaa
     8521 gctagccaac catgaattga atggtaccca caaatactcc actatcataa aaatcaagaa
     8581 aaatagaaag aggattttat caagattgag gtaaatctgt ttaagaccca attttttagg
     8641 tttttcaggt ttcataggca ctcctagtca aataattgag acaagtccaa gccaccaaaa
     8701 ggattgtttg ataagctact ttctgtctct aacaattccc tagcttgatc cgactctaag
     8761 aaggattcgt aaacacgcgc cgtcatccga gcatcctcta aactattatg agactgacct
     8821 tgaaatccaa gaaatgaggc aacagtttgc aatttgagat tggcaatacc atgtaaatct
     8881 gaactccgac gttcaaaagc ttcatcatac aaatccacct tgtactgttg gctatagtct
     8941 aaaccatgct ctgctaaaat aggtaaatca cttttagcag cattgtagcc tatcatcagc
     9001 aaagaaccca caaactcttg gaattcttct aagactttct caactggagg agcatctttt
     9061 aaggtctcag ctgtaatccc ggtcaaacca ttgataaagc tttttagagg gacgctggta
     9121 tgaacatagg aatcataggc atcgatttcc cgaccatctc taaaacgcac tgccgatact
     9181 tgaatcaagt gtgtttgtcc ttcgtgctga ttaaattcta aatcaaaagc aatgtaatct
     9241 tctaatcgtt ccattctgta cctctcctct actgtctctg ttctaatcaa ctatactatt
     9301 cacaaacaaa agaagccatc aggttagcat ttaacctaaa cagctccttg attatcctcc
     9361 aaataaacga gcaaaaaagc cttttttagt ggattggact tcttcttttg cttggtccag
     9421 ctctagctta agattttctt gatccttcat ggcttgaagg gtcaattgtt gttgctgatc
     9481 taattgtttg tctttctcag caatctgacg gtctttgata cgcatctgct cgtctttttc
     9541 tgataactga cgatccttgg cttttaattg ttcataaaga cgaagaattt ctgcattctt
     9601 ctcatccact agaatctcca tcagttcacg ttgtttgaca tcttcactga caggttcatc
     9661 ttcaaaaatc gtttttttat agatttcttc tagcttaatc aagccacttc tggtaacaac
     9721 tgttacccct ttgtcatttt tatctgtgtc ttcttctggt aattctttga cacggttatt
     9781 gattgcttgg cgagataatc ctaagacctc tgcaatctca ctgacggtca tttcaatact
     9841 cataatatcc tctgaaacgt tttctagctt ttctttactt aaatcttatc ataagctaga
     9901 aaaactgtca aatttccgct taatctaaag ccttcaaaaa ggccaacaag acttgggcag
     9961 agcgacgtcc agcttcgata ataaactcat caaaaaagat gtttgcttca tggttggcat
    10021 tgtcactcat agctcggatg actaagactg ggagattgag ggtatgcgct gcttgagcaa
    10081 tagctgcccc ctccatctcc acggctaaaa cttctgggaa atgggactta atcgcttcta
    10141 tcttgtcatt tcctgcaaca aaactatctc ctgtagcaat caaaccaaga tgccagtttt
    10201 ggtccaattg agataaactc tcttggattt gagcaacaaa ggttttgtct gattcgaaat
    10261 aaagcggttg ttgcgccatt tgtccataag catagccaaa agctgtgaca tccacgtcat
    10321 gataggctaa tttgtcagca atcacgacat ccccaacagc gataccttct gctactgccc
    10381 cagctgaacc cgtattaata agggcatcca cctggaaatg atcagccaaa atcgccacac
    10441 tcatagcaga catgacctta ccaattccac tttctacaag aacgacttca tgagaagcaa
    10501 tggttcctgt atgataggta ttccccaaaa caacttgctc ctggacatta tataaatgct
    10561 ggaccagata agccagttct tctggcatag cagcaataat tcctattttc atttcaattc
    10621 cttttctatt acaaaagttt cattgctaaa acaagcaaaa tcaagagaaa gatgaccgcg
    10681 aataagattt tattcaactt agaattgaag acatttctct tggtattttc aatgcgacgg
    10741 cttttatgaa tagatggttc gacctgaatc ttcaaggttt cctggctaaa accatgattc
    10801 ttaggattgg cataaccaaa acgggaagaa gaggttggta aaatcttagt ctcctcatta
    10861 tcatctagca aaggaggacc tgaaattttt tcgcctctat tagctctttc aatcatttca
    10921 tccgttaata aagatttacc catactgacc tcctctattt tttctgcaac tcccaatact
    10981 gaacagccat aattgtcttg gcatcacaaa tatgacctga ttggattaat tctttcgctt
    11041 cttctaagct cacttcaagg acttccaagg tttcatcctc atcctgcgga cgcggatttt
    11101 ccacttttgt caaatcgctt gctaaatata gttttaactt ctcattacaa aagccaatag
    11161 ctgaataaaa atcgtacaag agttctaatt tccctgtata ggctgtttct tcctctaatt
    11221 cacgaagggc agctgccaca ggggctgtgt tttctcctac ttccaatttt ccggctggaa
    11281 tttcgtaaga gacagcctcg atagctttgc ggtactgctt gaccaagatc agtttttgtt
    11341 catccgttac tgctaaaaca cagacagccc cattgtggaa aatcaaatcc cgttgggcag
    11401 ttcccttgcc ttctggtaat tcaacctgat cttggaccag tttaaatatt ggtccttgat
    11461 agatttcttt tcggctaagc gttttttctt caaactccat gataggctcc tactggttct
    11521 taggatgatg aggaagacgt gttgcatatt cgtctttatt gatctgacga ccgcgaccaa
    11581 tagcaatagc atctgctggc acgtctttag taatagttga accagcacca acgagggaat
    11641 tgtcaccaag ttctactggt gcaataatgg ttgaatttga accaacaaag acattgtctc
    11701 caatgactgt cttgtatttg tttttgccgt cataattgac tgtaatagtt ccagcaccga
    11761 aattaacgtt gcttcccact tcacagtttc cgatataagt caaatgacca gccttggtat
    11821 tctcaccgat tgaagatcct ttcacctcaa caaagttacc aatatgaact tgggcaccca
    11881 gacttgaatt tggacgaatg tgagcataag gaccgactgt cacaccgtct gcaacactac
    11941 tttcctcaat catagaattg gtaatgaccg ctcctgctcc gatagtgctg tccactacat
    12001 aagtaccgtt tgtcaaaaca gtctcagcac caattttcgt ttgccctttc aaggtaacat
    12061 tggcttcgat ttgaacttcc ggagcaatct caacatcaat atcgatataa gttgcttctg
    12121 gattgacaaa gctaacaccg ttgaccatat gtttatgatt gatgcgacga cgcataactg
    12181 actcagctgt cgcaagcgcc acacggtcat ttaccccaag actttcatca aaatctttca
    12241 aagtataagc gccaactttt tcaccagttt cacggaaaat accaatgacg tctgtaatat
    12301 agtattcgcc ttgagcgtta ttggtattga tatttttcaa agcctcaaac aaacgctcgt
    12361 tgtcaaagac gtatgttcca gtgttgattt ccttgatttg cttttcaaaa tctgtagcat
    12421 ccttctgctc aacaatacga agaacctcag cattgtcatt acgaacaatt cgtccatagc
    12481 caaaaggatt atccgtttca gcagtcaaga tagtggccac atttttatga ttgatatgga
    12541 aatcaatcaa gtttttcaag ctttcaccag tgattaaagg agtatctcct gcaatgacca
    12601 aggtgtgtcc tgacaaacct tctaagatag gttctgtcat cataactgca tgaccagttc
    12661 ccaactgttc agattgagtc acaaattctg tctgtccagc caagacctcc tcaaccaatt
    12721 ctgccttgtg tcctacaact gttactgtct tttcaggttg gatagctccc acactacgga
    12781 aaacatgttc caacatagaa atacccgcaa ccttgtgcaa aacttttggc aaatcagatt
    12841 tcatgcgagt ccctttaccc gctgctaaaa taatggcaaa atttgacata atcttctctt
    12901 ttctgtagaa attccctttt attataccat atttcaaatc attccgcact cttgaatgaa
    12961 aaaatgctct aaagtctctt ccttaaccca tttttttgat tttttttgat ttttagggta
    13021 gaattataag atatgagaaa acaaattcat ccacttattt tatttagttt tttggggatt
    13081 atgatgttca ttttaatcat caatcgccca cttaatgaca accaatcgtt taaaacaaaa
    13141 tccaatatag cacagattga agcacaggct ttgaaacact tagacaaacc gattattgac
    13201 ctctctggct ggcagcgtcc tgaagaaatc aactacgatg ccctctcaca aaatatttca
    13261 ggtgctattg ttcgtgttca cagtggtgct caaacgacaa aagaaaatga tgcttcattt
    13321 atcaatggaa tagacaaggc ctataagagt catatcactg aacttcaaaa gcggaatgtc
    13381 ccagttgctg tctacgctta tgtagctgga aaaagtgtcc aagaaatgga aaaggctgcc
    13441 gaagttttct acaatgctgc ctctccttac agccctagtt actattggct tgacgtggaa
    13501 gacaaaacca tgtctaatat gaacgaaggt gtcgaaaact ttcgagcaaa actagcatca
    13561 ctaggtgcta aaaacatcgg catctacgtt ggtgtctact tcatggaaga acacagtatt
    13621 gatacaggca agtttacctc tgtttggatt ccgtcctacg gctcagactc aggatttttg
    13681 gagagcagtc ctaaaactga tttagattat gatattcacc aatacacatc taaaggaaaa
    13741 attgccggct ttgaccacga tttagatatc aacgttatct ctcccttaaa aaataaagaa
    13801 gaaacctttc gaaaactttt tttaaaacct taaaagcatt tgtttatcat ttgctttttc
    13861 tttttgtgtc tgattgtgat acaatatagt aaggattttt tgaaatagaa atagttggag
    13921 gaaatatatg ctctcatggt tagcacgcgt tattaaaggg attgtaattg ctcttggatt
    13981 tatcctaccg ggaatttccg gaggggctct agcagcaatc ttaggaatct atgaacgaat
    14041 gattggcttt ctggcccatc cctttaaaga ctttaaagaa aatgttttgt actttattcc
    14101 agttgccatc ggtatgcttc taggaatcgg cttattttcc tacccgattg aatacctgct
    14161 tgaaaattat caggtctttg tattatggag ctttgcggga gctattatcg gtacagttcc
    14221 tagcctcctc aaagaatcaa ctcgagaatc tgaccgagac aagattgatt taacttggtt
    14281 atggacaacc tttatcattt ctggattagg actctatgcc ttaaattttg tcgttggaac
    14341 cttaagcgcc agctttctta acttcgtcct agcaggcgca ctattggccc ttggcgtctt
    14401 ggttcctggc ctcagcccat caaatttact tttgattttg ggactctatg ctcctatgtt
    14461 gactggtttt aaaacttttg atctcttggg aaccttcttt ccgattggaa ttggtgcagg
    14521 tgcaactctc atcgtttttt caaaattgat ggattatgcc ttaaacaact accactcacg
    14581 cgtctatcat ttcatcatcg gtatcgtcct atcaagtacc cttttgatct taattccaaa
    14641 tgcaggaaac gctgaaagta tccaatacac aggactttca cttgtcggtt atgtcatcat
    14701 cgccttcttc tttgcgctgg gaatctggct tggtatttgg atgagtcaat tggaggataa
    14761 atataaataa tggcaaaaaa agttaaaatc aaaaaaacat tggtggaaca aatcctatct
    14821 aaagcagcta tccctcatca gggaattcaa atcaatgccc tagaaggaga gcttcctcaa
    14881 ggttatgaac gagatcagat tttcaaaacc ttggcgcttt tgggagacaa gaccggaccg
    14941 attatcggaa ttgtccctat cactcagcac ttgtctgaaa agaaactagc taaaatttct
    15001 ggcaataaaa aagtgagcat gattccacaa aaggacttag aaaaaacaac tggttacatt
    15061 catggagcca ataatcctgt cggaattcgt cagaaacaca attatcccat ttttatcgat
    15121 aaaattgctc tagatttgga tcaaatgatt gtctctgcag gcgaagtcgg acacagcatt
    15181 atcgtcgcgc cacaagactt ggctagcttt gtaaaggcag actttgtaga tattttggag
    15241 gacatcaagt aatgaaactc tactttgtcc gccacggtcg taccctctgg aaccaagaag
    15301 gtcgttttca aggtgctagt ggtgattctc ctcttcttcc tgaatccatt gaaaccctaa
    15361 aacgacttgg tcagtatctc aaggaaattc cttttgatca gatttattca agtgatttac
    15421 ctcgagcggt caaatctgct gagattatcc aaagtcaact ctataccccc tgttctttag
    15481 aaatcgttcc taatctccgt gaatggcaac ttgggaagtt agaaggtttg aaaattgcaa
    15541 ccttggaagc tatttacccg caacaaatcc aggcttttcg ttcaaatctt gctcaatttg
    15601 acactcgaat gttcggagcc gaatccctct atagtacaac tcaacggacc atccaattta
    15661 tcaaatcatt aaaagatagt ccagctgaac gtattctaat tgtcggacac ggcgccaatc
    15721 ttactgccag tcttcgtact ctcctaggct ataaagaacc acttcttcgt aaagatggcg
    15781 gtctagcaaa tgccagcctg accattatag aaacccatga ttttgaaaca ttcactctca
    15841 atacttggaa tgatacttct tatcaatcat aattatagcc tagccttctg aactagaacc
    15901 ataggagata tagtcagttg aaacaaaaat aagataaaag agcctcgtaa aaaggtattg
    15961 caacttgcca ataccttttt tgatatgaac acgtgtcttc tcaacaggat tgtagagcaa
    16021 aatgaaataa gaactgaata atatgatttg agaatttaaa tcaatttata agaatgtttt
    16081 agaagcagtt atgtactatt ttagattcac ttttctatac taagatgagt agggaggaaa
    16141 aggtaaaagt ttatgcccaa actcttcaca taagaactct agcttaccca ttctatggaa
    16201 tcttgcatta tccattaaaa cttccagact catacccttc taaaatctat tcaaaccacg
    16261 tcagcttcac attatatatg ttggttacct cacaagtttt atctgcaacc tcaaagctgt
    16321 tctttgagca gcctacagct agcttcctag tttaatcttt gcttttcact gagtatcaag
    16381 ttaaaaaatg aggctggtca aaaagtcttt aaaataaaaa aaacgcatat tatcaggtgt
    16441 taaatgaact gcaccccaaa agttagacag aaaaaatcta acttttggag tgtttttatt
    16501 atgaaa
//
LOCUS       DAVLCS010000041        15970 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLCS010000041 DAVLCS010000000
VERSION     DAVLCS010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15970
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.041"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(146..2692)
                     /locus_tag="VXC78_001673"
     CDS             complement(146..2692)
                     /locus_tag="VXC78_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV0583704.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(2815..3255)
                     /locus_tag="VXC78_001674"
     CDS             complement(2815..3255)
                     /locus_tag="VXC78_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV0583705.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(3230..4099)
                     /locus_tag="VXC78_001675"
     CDS             complement(3230..4099)
                     /locus_tag="VXC78_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV0583706.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(4141..4869)
                     /locus_tag="VXC78_001676"
     CDS             complement(4141..4869)
                     /locus_tag="VXC78_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0583707.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(4877..5356)
                     /locus_tag="VXC78_001677"
     CDS             complement(4877..5356)
                     /locus_tag="VXC78_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0583708.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            complement(5367..6065)
                     /locus_tag="VXC78_001678"
     CDS             complement(5367..6065)
                     /locus_tag="VXC78_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV0583709.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEARI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(6058..6324)
                     /locus_tag="VXC78_001679"
     CDS             complement(6058..6324)
                     /locus_tag="VXC78_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV0583710.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(6390..7316)
                     /locus_tag="VXC78_001680"
     CDS             complement(6390..7316)
                     /locus_tag="VXC78_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV0583711.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(7391..8206)
                     /locus_tag="VXC78_001681"
     CDS             complement(7391..8206)
                     /locus_tag="VXC78_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583712.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(8210..8530)
                     /locus_tag="VXC78_001682"
     CDS             complement(8210..8530)
                     /locus_tag="VXC78_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0583713.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(8827..8907)
                     /locus_tag="VXC78_001683"
                     /pseudo
     CDS             complement(8827..8907)
                     /locus_tag="VXC78_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(8951..10948)
                     /gene="metG"
                     /locus_tag="VXC78_001684"
     CDS             complement(8951..10948)
                     /gene="metG"
                     /locus_tag="VXC78_001684"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0583714.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIIAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(11072..12331)
                     /locus_tag="VXC78_001685"
     CDS             complement(11072..12331)
                     /locus_tag="VXC78_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0583715.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSSFTVSGKEEEIPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(12333..13034)
                     /locus_tag="VXC78_001686"
     CDS             complement(12333..13034)
                     /locus_tag="VXC78_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583716.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(13018..14217)
                     /locus_tag="VXC78_001687"
     CDS             complement(13018..14217)
                     /locus_tag="VXC78_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV0583717.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            14482..15828
                     /gene="gor"
                     /locus_tag="VXC78_001688"
     CDS             14482..15828
                     /gene="gor"
                     /locus_tag="VXC78_001688"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV0583718.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
BASE COUNT         4735 a         3594 c         2852 g         4789 t
ORIGIN      
        1 tcgaaacttt gaaaacttca aaaaacggat ttttatcgct ctgaatatca aaaaagaaag
       61 gacaaaattt gtcctttctc gagcttagct ttttttcaac ccactacagt tgacaaagag
      121 ccttttcttt ttattttagg cttatttatg catttccgta ttgaagaaca actgcttcga
      181 ctgcagcttt ttcacggcta atcaagtcaa cacgtgctgc aatttccttg attcccatac
      241 cgatgttacg gctaagagca aggtcagaaa gttgcggctc aaagaactcc ttgtattccg
      301 ccaagcgttg ctgagtctta aatacatgag caggaaggat aacaaagcta tcaaagctca
      361 tatctcctcc aagggctgcc ttaatccaag cccagttttc acgcgcccaa gaccaagctg
      421 ttttctgagt tgcttgatga gctaggaatt ggtaatacca agcagacaag tcctgtggtt
      481 tgaccacaaa tttgtccttc caagaagtaa tcaagttttg gatattatcc gcatctgtac
      541 tgtatgcaag agctgctgcc aactggcgtt taaagacagc atctgttgcg tgagtataag
      601 tatcaagata aagtgctaac aagtctttag tctcatgatg tttcatctca ttaatcagaa
      661 cttgtgaacg aatagctgct gggagttctg caagattctc cttgtgtgtt gcgaagattt
      721 ggctagcgac ttgacgagct tctgcatcat ttgagcgaat catcatcgaa acagccagct
      781 gacgaaccaa ttcatcctca tctgattctc cgtctttagc ttcaaaacca agacggtcat
      841 agttatgacg agccaattta gcaaccagtc ctttgaaggc tgtttcagca tccgttcctt
      901 catcaataaa gcgctcaagg gctgaaatca cttgagaaac agctgaaacc accagataag
      961 actcttcctt agcaagttta tcaagaactg gaagcaagtc tgcataagaa atgtgccctg
     1021 cctcagccaa caaacgacgt tcttgaacaa tttgcagttt gcttgtgtta tcaagtgtct
     1081 ctagctcagc aagaacagct tctaacaagt ctccttgata gtcggtaata tagtgggcag
     1141 tattttcagt gttgagacga agagctcctt cattttcagc aagaagagct gcgtagccag
     1201 ggatttcgat actttcagtt tcgagtgtat caggcaagcc tttccagttg ctattgaggg
     1261 gcaccaccca gagacggttc ttgtcttcgt tctcaccgat gaagaattgt ttttgtgaaa
     1321 tcttcaagac atcattttca actttgacag taagaactgg gtaaccaggc tgttccaacc
     1381 aagaatccat gaaggctgcg acatcacgtc ctgacgcttg accaagggca tcccaaaggt
     1441 cactaccaat ggtgttgctg tattggtgtt tttcaaagta ggcatgcaaa cctttagcaa
     1501 aatcagcatc tcctagccaa cggcgaagca tgtgcatgag acggcttcct ttggcataga
     1561 cgatagcgcc gtcaaagagt gtattgattt catctggatg tttaacttcg acgtggacag
     1621 actgaacgcc atcagtagcg tcacgttcaa gagcaagagg tactccacct gtttggaaat
     1681 cttcaaagat attccagctt ggttcgatgg tatccacaca gacgtattcc atcatattag
     1741 cgaaactttc attgagccaa aggtcatccc accatttcat agtcacgagg ttcccaaacc
     1801 attggtgagc caattcatgg gccacaacaa gggcaacttg ttgacggcta gcaaatgtag
     1861 agttctcatc gacaaccaag taaacttcac ggtaggtcac aagaccccag ttttccatag
     1921 caccagctga gaagtcagga agggcgatgt ggagagattg aggaattgga tacttaactc
     1981 catagtaatc ttcgtaaaac tcgatagagc gaacagcgat atccagtgag aaatcaagat
     2041 ttgaaagtgg atgtgctttg gttgagtaga cacctaccag ggtaccattt ttagttttag
     2101 cggtcacccc ttgcaaatca ccagcaacaa aggccaacaa gtaagaagac atgcgaggtg
     2161 ttgtctcaaa cttccagata cctgtttcct tacggttttc aacatcgatt tctggcatgt
     2221 ttgacaaggc caattcacct tctgcttggt caaagcgaag agagaggtca aaagttgctt
     2281 tggcttcagg ctcatccaca catgggaaag cttcgcgcgc aaaatggctc tcgaactgag
     2341 tagacaagac ctccttcttg actccatcaa ctgtataata agaagggtaa atccctgtca
     2401 tgttgtctgt aattttacca gaaaaggcaa gaaccaattc aacttgacca gcctcagcca
     2461 attcgatatg aagggcttca ttgtcatggt caactgtaaa tggacgagct tgacctgcaa
     2521 cttctacaga ggtgatttcc aagtcttttt ggtggaggga gatgcggtca ctctgtgctt
     2581 gaccagtgat ggtcactttc ccagaaaaag tcttggtctc acgactcaaa tctaaaaata
     2641 aatcataatg ttcaggaaca aattgcttaa taaaatgttc aactgcttgc atagttttct
     2701 cctattctaa gtttaagagc tgctgctctt cttcaaacaa acttattata tcatattttg
     2761 cttgaaaaaa aaggattgga cagcgatttc caaaactttc ttccttctaa tagtctacag
     2821 tgggtagacc ttgcgaaatt cttctaaaac aaccttgctt tcaggtgtaa aagtcagccc
     2881 tacttcaccc aaacagtctg tgaaaaagtc ctcatgaacc tggcgccaat aggcaagtga
     2941 tttgtctccc tcaccttcct taaaggcatg ttgcgcagaa acttgattga agagttcaac
     3001 agaaaccttt gtaatttcga caatgcagac agactgattt tgactatcta aaatgatatc
     3061 gaaggtccct acttggggaa gtggttcgtc ttctagtaca tagaggtcat aggctgatgc
     3121 tgttgctgtc ttttctcctt taaacaccaa atccgctaaa agatctggtt caactccaaa
     3181 agcccaagca tcgatttcat ctccgatcaa aggattgatt tgcttgtatt tattccacat
     3241 ttcttgcggt atcatgggta ctcctttgta attttttact ttcttctttt atgtgtttaa
     3301 gatgatctgg atggtcaatc tctaaatcaa aaatctctgg aatagaactg tagtggataa
     3361 tgcacttgat acccaactga ttcatttttt gtatgaaaga agtattcaga tagcctgcta
     3421 cagcaaaatc aatcttgttc tttcttgctt tatcctgcat atctcttagc atatctaaca
     3481 ttattggact ttccatatca tgccattgac tgtttctcat agtcgcaaaa acaaaggaag
     3541 tcaaatcatt cattccaact acaatctttg aaatgcccgt ttccagtata ctagataagt
     3601 caaaatacgc tgacggtaat tcaatcatcg ttccgacttt cccagtaaaa ccctgctgac
     3661 gcaatactgt aatagcttgt tttaattggt cggcatcatt gacaaaagga aagataacag
     3721 atagattggg gttggtttga taaacttctg taacgacatg tgcttcagcc tgaaattcat
     3781 ccaaacacgc cagtaaacgc ctggttcctc tatagccaaa caagggatgc ccttcgtcaa
     3841 aaaactctct agtccccact aaacaattgg cttctgtatt cgttaattca gaaaaacgat
     3901 accaaacttc ttcatctgag tacagggagc agatagtctc tagataatct tttacaaatt
     3961 gctgacaact tgctaatatg atgttttgat taagctctct caacaaatat tccccacgaa
     4021 tcatgccgac gtggtgaaat agttgaggat aaattttttc aagaattttt tcgccactaa
     4081 gggcaagttg atttctcata gccattcacc tcgtcttaaa agatacaata tcatatataa
     4141 ttatatcaaa atttcctcta gttcaaaagc ttcataaggt tcagataact catatcctaa
     4201 aaattctgct acttttttgg aagcctcatt atgagcatcc caaagtggaa acatatctct
     4261 atttaaactc tctagaatca ttgcagcacc aagcttttta gcaaatccat ttccttgttc
     4321 gtttggtcta gttgcaactt ccacttcaac tgctttacgg taaactaacc ctgaggaaat
     4381 cccagcaatc agttcattat ttttaagaat cacaaagcca aatccacctt ttaaaacaaa
     4441 atcctgatag gactcaaaat ccccctgtaa atcctgtgac cattcttccg tagaaaagca
     4501 gttataaata tgattatcaa taggcacaat attgtaacct tcctctaaat gagtaactag
     4561 attatttaaa aattcaactt gaaaatttgc cttatcttta aaagaatagc gagtaaaaga
     4621 atttagcccc acttttcgat gcagaaaatc ttgccaatta gtattttctg aaataataat
     4681 cttataatct aaaccatatt ttctaacaaa atcttcccaa aatctggaat ccaactcccc
     4741 tgctaggtat agaaaattcc caacatcata aaagcttgtt gtcctatcat tgtttcggta
     4801 gacagttcca atttgagatt taagaccata gagaaccata tttttcttcc atgttttaaa
     4861 tagttccatt atccctctac ttcaccttcc aattcatgta agaagtcttg tccagttctg
     4921 gcaatcctaa taattcagac ttaaccttca agactaatgg cgatgcattt tcttctgtaa
     4981 tctcttgaat atccatccaa atatatccaa gtgaatcatt cgcaccatca gacacagctt
     5041 ccgaaatcgt aacttgaggt gcactctcat tcatttcaac atcatacaag gctatgacat
     5101 ggtgaaccat aaaatttttt aactcttccc tgacgaaaac atcgtagatt cgaggattag
     5161 agtagcttct aacagtaaat cccgtctctt ccataacttc tctagtcagc gtttccgtca
     5221 gtccttcacc aagttgctga ctgcctccag gtagatcata ccgatgttga taagggcctc
     5281 tcgttttttc aatgcaaagt aactttccat tttcaaagca aacacagtag accccaaagt
     5341 gatttttgat ttccatccaa ctcctcctac ttcaaagacc agccaccatc tattgtcaga
     5401 atttgtccct gcatggcaga tgcctttcca ctggccaaaa agagactgac ttctgccact
     5461 tcctctggtt caatccagcg cttgattggg gtttcactag ccacccagtc agctaagcca
     5521 cctgtctcaa aatccgcagc ggtcatagct gtcttgactg ctcctggagc gataccaaag
     5581 acctgaatcc tagcttcagc atagtctaga gccaactgct tggtgaagcc agccaaggca
     5641 tgcttggatg aagtataggc gtgaccacct ccacctgcta ggctagaagc aatggaacac
     5701 atattgatga tgattccctt tttattttcc agcatttgtg tcaaataata ccgagtcaac
     5761 tctactggaa taatgtagtt gatttcaaaa atctcttgaa tgtcctgcgc cgtttgttcc
     5821 aacagtggtt tgtaagcatc caaaactccg gcagtattac acaaaacatc cacctgaggg
     5881 caccagtcaa aaataggttc caagtccaag gtcaaatctc tctgtaaaaa gtgaaaatca
     5941 ccctctaaga gtggcttttc accttggtca actccataaa cttgatagcc cttctctaaa
     6001 aagaggcgag cttgagccaa tccgatccct gaactcactc ctgtaatgag tacacgttta
     6061 gtcatgcact tctacccaat ccgttgccaa aacatcacaa actgtcgggc tccacatgga
     6121 aaaaccttct ccttctccag aaacgttgat taggaaataa ggtgtcattt caagtgcaag
     6181 cccattttgc tcgatggtat caaagagttg gacatagttt tccgcacctc cccaaccagt
     6241 tcgtacatat tttctcttag cctttaaccc aggcaggatc tcttcaaatg tcatgttttt
     6301 ctcctttaat tctacattct tcatttaatt atagcaaaaa accactttat acggcttttt
     6361 gactgtgagt tattcaaacc tgctactact tacggcaaat tattccctgc agcaagataa
     6421 atttcatacc attcttttct tgttaagcta aagtttgccg ctcggctaac ttctctcaag
     6481 tgcttaggat ttgttgtacc tacgactgcc tgcatttttg ctggataacg caatatccaa
     6541 gaaatggcaa tagttgaaga ggttactcca tatttaatag ctaaacgatc aagtacttga
     6601 tttaaagctt gaaatttctc atttccaaca aagttccctt taaaataccc gaattgcaag
     6661 acagaccatg cttgaatgac cacatcgtgt aattggcaat attcaaaaat gctgccatct
     6721 cgcatagctg cttgactatc ttccatatta acatgaaaag ctgattcaaa tcctggagta
     6781 aaagccgcac tcaattgtag ctgattaaca gctaacggct gcttgacatc ttttttaagc
     6841 aactccatca tcataggatt ttgattagaa actccaaaat ctcgaacttt accttgttta
     6901 taaaggagat caaaggcttc tgctacttgg tcagattcca tcaaagcatc tggtcgatga
     6961 aggagcaagc tatctagatg atcaatcttc aatctttgca aaataccgtc tactgatttt
     7021 ataatatagt ccttagaaaa atcaaaatag gtaaattctt caatgcgaat gccacatttg
     7081 gactgaatcc acatcttttc tcttaaatct ggacgatttt ttaggacaag acctaacagt
     7141 tcttcacaac gaccacgacc ataaatatca gccaagtcga aggcattgat tccaacagaa
     7201 agtgctgttt ctacaagctc ttcaacttct tttacagact tatcttttat tctcatcatt
     7261 ccgagaacaa tttctgataa ttctttgtca tcttgaccaa gagttatgta tctcatcaaa
     7321 tttttctcct ttaatttcta acattcttcc cttcattata acaaaaaacc gctttgcaac
     7381 ggctttttga ctatacttca ctccatttta tcttcttaaa cccacggaac aagacaaaaa
     7441 tgccaataaa gaggacagct aaaggaataa cttttgtaag gaaaacattt gaaattccca
     7501 tccactcata ataacggagc agagaaccca ccacaagatg ggcaataatc atactgacaa
     7561 atggacgaaa gaccgcttct ttccaattcc aaataccgat aactagcgaa atcgtaaaga
     7621 cagacaaact atcccaggga gccggaatat aaaaggctcc ttcttgtatg aagcttgcca
     7681 ttcctacata tcctaaaaca actagaagaa ctatagtccc aacaacaatg taagtgccaa
     7741 ttttcatttt aggagaatct tggactaaac ttcttcgtaa aattgtggcc acaagtccaa
     7801 atccaatcag aaaaataaga agttgcccta aaaatgtgag caaattgact gttaagagag
     7861 gacctttaga aaaatcactt agtagttgat aataacgtaa taccgccagg acaagaattg
     7921 gcgtcaaaag ggactctttg atagaactgc gaggtgctcc cttgagaatc tctttcatta
     7981 tttttttagg attcttacct agataatcct ctgcactcat gccatctcgt tctgcttctg
     8041 agaaatctag catcatcaaa tagatctgct ctctgagata gtcttcatca tagagaaatc
     8101 cagcaagatt aaaactttcc cacaactcct caaaatactt ttgattctcc tcagaaaact
     8161 catgtagcaa agcgcttgtt tcttcgtaat acttcatttt cttcatggtt taacccccat
     8221 tcttaatccc ttctactttt tgactcaaat cgtcccattg ttgccaaaag actgagacac
     8281 gctcttctcc ttctttcatt aatgaaaaat acttccgatc tggaccatct ggcgacgggc
     8341 gcatgtcgcc tcttatccat tgattttttt ctaacttttg caacaaagga taaatagttc
     8401 ctggaacgat agtatcaaat ccagcctctc gcaaagtctg aaccaactca taaccatacc
     8461 gctctttttg accaatcata tccaagacac aaccttcaag aacacctttt aatagctgag
     8521 tttctttcat cacttttccc ttctaatcta ttttgtaata cctactagta acttcaccta
     8581 tagtatatca cttctacact agtttgtaaa gcataatagt taatactctt cgaaaatctc
     8641 ttcaaaccac gtcagcgtcg ccctacctta tgtatggtta ctgacttcgt cagtttcatc
     8701 tacaacctca aaactgtgtt ttgagctgac ttcgtcagtt tcatctacaa cctcaaagca
     8761 gtgctttgag ctgacttcgt cagtttcatc tacaacctca aaactgtgtt ttgagctgac
     8821 ttcgtcagtt tcatctacaa cctcaaaact gtgttttgag caacctgcgg ctagcttcct
     8881 agtttgctct ttgattttca ttgagtataa ataaaaaaac agaactagcc tgaactagtc
     8941 ctgtctactt ttacccaatc acacttccat ttggtacagc tggatcaact gtgagaaggg
     9001 ttaatttgcc atcatgttca gctgagagaa tcataccctg gctgacatat tttttcatca
     9061 ttttacgtgg tttgaggtta gcaatgattt gaactttctt gccgaccaat tcttgttcat
     9121 ttggatagta ttttgcaatt cctgaaagaa tctgacgatc ttctccatca ccagcatcca
     9181 agcggaattg aagcaactta tctgaacctt ctactttaga cacttctttg acttctgcga
     9241 cacggatttc aaccttgtca aagtcttcaa acttgatttc atccttgttt agtttgagct
     9301 caacttcgtc cggattccat tctttttcga ctgctggttt attgccttcc atttgttcct
     9361 tgatataggc gatttcttct tccatattta gacgtggaaa gataggtgtt cctttggcaa
     9421 ctacagtcac atctgctggg aagtcagcca aactcaagtt ttcaagacta gaaacttctt
     9481 ccaaaccaag ttgagtcaaa actgcacgac tagtttccat cataaatggt tcaatcaagt
     9541 gagcaactac acgaatgctg gctgccaagt ggctcatgac acttgccaat tggtcacgaa
     9601 gagcttcatc cttggccaag acccatggtg cagtctcatc gatgtattta ttggtacgag
     9661 agatcagagt ccagactgct tcaagcgcac gtggatagtc aactgcttcc atgtgtgtat
     9721 ggaagtctgc gattgattgt tctgcaacct cagcaagaac atgatcaaat tcagtcacac
     9781 cttctacata ggcagggatt tgtccatcaa agtacttatt aatcatggaa accgtacggt
     9841 taaggaggtt cccaaggtca ttagccaatt catagttgat acggccgaca tagtcttcag
     9901 gagtaaaggt tccgtctgaa ccaactggaa ggttacgcat gaggtagtaa cgaagtggat
     9961 ctagtccata acgctctacc aacatttcag ggtaaacgac attccctttt gacttagaca
    10021 tttttccgtc tttcatgaca aaccaaccat gggcaatcaa acgatcaggt aatttaacat
    10081 ccaacatcat aagaaggatt ggccagtaga tagagtggaa gcgaaggata tcttttccta
    10141 ccatatggaa gactgttcca ttccagaact tgtcaaagtt accatgttcg tcttgagcgt
    10201 agccaagagc tgtcgcatag ttaagaaggg catcaatcca aacgtagaca acgtgttttg
    10261 gatttgatgg gacaggcact ccccatgtaa aggttgtacg agataccgcc aaatcttcca
    10321 aacctggctc gatgaagttg cgtagcattt cattaaggcg accatctggc gtgataaatt
    10381 caggatgagc tttgaaaaat tcgaccaaac ggtcttggta tttgctaagg cgaaggaagt
    10441 atgattcttc agaaacccat tcaacctcat gacctgatgg agcaatacca ccagtcacat
    10501 ttccagcttc atcacggaaa acttctgcca gctggctttc tgtaaagaat tcttcgtctg
    10561 atactgaata ccaaccagag tattcaccca agtagatatc atcttgagca agtaagcgtt
    10621 caaagacttg tgcgacaact ttttcatggt agtcatcagt tgtacggata aatttatcgt
    10681 atgagatatc tagtaattgc cagagttctt taactccaac cgccattcca tcaacatagg
    10741 cttgaggtgt aataccagct tcttccgctt tctgctggat tttctgacca tgttcatcaa
    10801 gacctgtcag ataaaataca tcgtagccca tcaggcgttt gtaacgtgct aggacatcac
    10861 atgcgatagt tgtgtaggca gaaccgatat gaagtttccc agatggatag taaatcggcg
    10921 ttgtaatata aaaatttttt tcagacataa tttttccttt ccaggcaaat gaaacctgtt
    10981 tttctaacac ttcattatat cacattttta atgaatttcg atagggaaat ccatacaaaa
    11041 acaagataga cgagtgtcca tcttgttgat ctcattcata acgaagggct tcaattggat
    11101 caagtttcga tgccttgttg gctggcaaga ctccaaaaat cataccaaca ctagccgaaa
    11161 ctgcaagact aaatagggca actgggattg atactccaac ttctatacct tctattaaac
    11221 cttgcagtaa caaacctgct aaggcagtta aaccacttgc aattgtcaag ccaattaagc
    11281 cacctaacaa ggtcaaaatc atggattcaa tcaaaaactg aattaaaata ttggcacgtg
    11341 ttgcgcccaa agccttacga agaccaatct cacgagtgcg ctctgtcacc gaaaccagca
    11401 tgatgttcat gacaccagtt cctccaacaa agagagaaat ccctgcgatg gaactaataa
    11461 tcgtcgtcat aaaactaaac gattgttgaa tttctgcaaa tacaacggac tcatctgcca
    11521 cctggtattc tccctgttgt aagcctgcaa gctctgtcat ttttcgtgcc agttctggac
    11581 ccagagttgg ggttaaactg gtatcattca ctcgaaagac aatactagct atttcatcta
    11641 tattaaaatt cgcagcaagg gagatattgg tagtaatagg caagccacca aacccatata
    11701 tttttgacct tttagcctcc ggactagtat aaaccccaat gacccggtaa ctaaatccat
    11761 tgacttctac aaccttgtta atagcctctt gaggagattc aaataaacta atggacaatt
    11821 cctcatctag caaaataaca cttgcaaact ctttgaaatc ttgctctctc agactacgac
    11881 ctgcaataat ttcattctta acagcgtcca tgtaagttct gtttccacct gtcaaattag
    11941 cattctcaac ctttttatct tgataggtca agatggcatt cgttgaattg gttacatagt
    12001 aactatccac tcccttcagt ttagctgcct cttggaccca ggattcttgc ggttttggcg
    12061 gttcaacagg aatttcctct tcctttccag aaaccgtaaa agatgattgt ttctgagtaa
    12121 aagaaccatc tttacttttt ttaggagaga aaaagacgct aatatttttc tgagatttag
    12181 tcatatcttt attgacttga cgagataggg aatcacccaa agccataatc acaacaactg
    12241 atgaaacacc gataataatc ccaatcatag taagcaaaga acgcatcttg tgagccatga
    12301 tagatgaaaa ggcaaatttc agattctgca tcttagtttt cctcctttcc taactgagca
    12361 ctgtcagacg aaatgacccc atcccgaatg acaatctgac gtttagcata ggcagcaatc
    12421 tcaggctcat gcgttaccat gataatggtt tttccttctt tattcaaatc aaccaataat
    12481 tgcataattt ggttacctgt tttggtatcc aaggctcctg tcggttcatc cgctaggata
    12541 atagaaggat tgtttaccaa ggcacgcgca atggctacac gttgcttttg accaccagat
    12601 aattctgaag gtaaatggtg actacgttct gtcaattcaa ccttgtctaa atattcctca
    12661 gccaacttgc gacgttttga agacgaaact cctgcgtaaa tcaagggcaa ttctacattt
    12721 tgcagagcat tgagcttcga tagaagaaag aactgctgaa agacaaaacc gatttgttgg
    12781 ttacggacct tagccagttg tttttcacca agcccagcca cttcttgacc ttcaagataa
    12841 tattctccac tggttggtgt atccaacatg ccaatcgtat tcatcagagt ggacttacca
    12901 gacccagatg gtcccatgat ggctacaaat tcaccctcat tcacttctag attgatattt
    12961 ttgagaacct gcagttcttg gtcaccatta cggtagcttc tgaagatatt ttttagacta
    13021 attagttgct tcatcagcct tcacctcttt tccttcttcc aaggaagatg ttggattact
    13081 gatgacctta gcaccattcg ttaaaccaga agtgatttct tgattttctg cgtcagcatt
    13141 tcccaatgaa acctcaactt ttttagcctt ttgttgttca tccacaatcc agacataatt
    13201 tttactatca tccattacta gactgctaac aggaacaaga atagccttag ttttgctttt
    13261 aacctcaatg ttgacagaaa aaccctgttt caaatcacca acctcgcctg tcacatcaat
    13321 agtataaggg tatttagaac ctgtattatt cccggctgct ggactagctg cttcaccatt
    13381 gtttttagga tagtcagaaa tatagcttaa tttcccagtc cattttttat caggatacac
    13441 tttagaagta aagcttactt cttgacctac agaaaggttg gctagattgt actcagacaa
    13501 ttctcccttg acttgtaaat tttcattgct gacaatatga accataactt ggctcgcccc
    13561 tgttggagat ttagaaacat tgctattgac ttcgactaca gttccctcta gggtactgag
    13621 aacagttgtt gcatccaatt gactttgagc cttgcttaat tgcgctgcag catctgcacg
    13681 cgcatcacgg gcatcaccca attgagcgtc aatagaagca acagaatttc cagccactgg
    13741 agttgggctt tgcaccgttg catcttctcc tcctactggc gctggtaact gtggagccgg
    13801 agctgaagcg gcttcatttc gtgcttgatt gagttcattg atatgacgat ctgccttagc
    13861 tactgctcga ctagctgaat cataggccgc ctgcgcttct gaactactgt acttgactaa
    13921 agcctgccct tcgctgacct tatcgcccac agaaacaagg atttcatcta aatcaccctt
    13981 actagcatca aaataaacat attgttcatt ttttgctgtt actgtccctg acaataaaac
    14041 agaggaggcc acgcttcctt ccttggcaac aacaagatga gtaggctcat cttttagagc
    14101 agtctgagaa ggttgtctaa agagtaaaat ccccccagca cccaatacaa ctacactcgc
    14161 agcaccgatt gctgcataca gttgccactt tttagcttta ccattctttt tcttcataat
    14221 gaaactcctt ttctttttta caatactttg ctattatacc aaatttccct ccagcaaaca
    14281 atacagttca ggattaaaca atcgttcgga attttgcttt tctattgtac tagatatata
    14341 atacactatc ttgacttatt tggcaagctt ttttgcaatt ttttgtgcgt agcagatttt
    14401 tgcaatcaaa tcaaaaaaag aataaaatat aactatcaaa aaagacgctc tactatttaa
    14461 aagattacaa aggagttttc aatgagagaa tatgatatca ttgctatcgg tggaggtagc
    14521 ggaggaatcg ctaccatgaa ccgtgctggt gaacatggag ccaaagcagc cgttattgag
    14581 gaaaagaaat taggtggaac ctgtgtcaac gtcggttgtg ttcctaaaaa aatcatgtgg
    14641 tacggggcgc aaatcgctga gactttccat caatttggag aagactacgg ctttaagact
    14701 actgatctta actttgactt tgcaacccta cgtcgcaatc gtgaagccta cattgatcgc
    14761 gctcgttctt cttatgatgg tagttttaaa cgcaacggtg tagacttgat tgaaggtcat
    14821 gctgaatttg tagattctca tactgtaagc gtaaatggtg aactgattcg tgctaaacat
    14881 atcgtgattg ctacaggtgc ccatccaagt attcctaata ttcctggtgc tgagctaggt
    14941 ggctcttctg atgatgtatt tgcctgggaa gaacttccag agtcaattgc cattctaggc
    15001 gctggttata tcgccgttga attagctggc gtactccaca cttttggtgt caagacagat
    15061 ctctttgttc gccgcgatcg tcctttacgt ggttttgatt cctacatcgt tgaaggtttg
    15121 gtcaaggaaa tggaaagaac aaacttacca cttcacactc acaaagtccc tgtcaagtta
    15181 gaaaaaacta ctgacggcat taccattcat ttcgaagatg gtactagtca cacagctagc
    15241 caagttatct gggctacagg tcgccgtcca aacgttaagg gcttgcaact tgaaaaagct
    15301 ggagtgactc tgaacgaacg tggctttatc caagtggatg aataccaaaa tactgttgtt
    15361 gagggaatct atgctctagg tgatgtaacg ggcgagaaag aactgactcc agttgcaatc
    15421 aaggccggac gtaccctatc tgaacgtctc tttaacggaa aaactactgc aaaaatggat
    15481 tactcaacta ttccaactgt tgtcttttca caccctgcta tcggaactgt tggtttgaca
    15541 gaagagcaag ctattaaaga atacggtcaa gaccaaatca aggtttataa atcaagcttt
    15601 gcatctatgt actctgcttg cactcgcaac cgtcaagaat cccgtttcaa actcataaca
    15661 gctggttcag aagaaaaagt tgtcggactt catggaattg gctacggcgt tgatgaaatg
    15721 attcaaggat ttgccgttgc tatcaaaatg ggagcaacca aggctgactt tgatgcaact
    15781 gtggcaattc acccaactgc atctgaagaa tttgtaacca tgcgttaatc gaaacaaaag
    15841 aagcaaagca aaaaacactt ctaaatatca aaaagcgagt atttccgtag ttggagatac
    15901 tcgttttctt atgttttatt ttatagtatg ttgaagtaag atatgcaaaa atcaattaac
    15961 aaaccatagc
//
LOCUS       DAVLCS010000042        15955 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLCS010000042 DAVLCS010000000
VERSION     DAVLCS010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15955
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.042"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(549..857)
                     /locus_tag="VXC78_001689"
     CDS             complement(549..857)
                     /locus_tag="VXC78_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0583719.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(854..1162)
                     /locus_tag="VXC78_001690"
     CDS             complement(854..1162)
                     /locus_tag="VXC78_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0583720.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1167..2462)
                     /locus_tag="VXC78_001691"
     CDS             complement(1167..2462)
                     /locus_tag="VXC78_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0583721.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2480..3889)
                     /locus_tag="VXC78_001692"
     CDS             complement(2480..3889)
                     /locus_tag="VXC78_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0583722.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKRS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4047..4775
                     /locus_tag="VXC78_001693"
     CDS             4047..4775
                     /locus_tag="VXC78_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0583723.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5234..5428
                     /locus_tag="VXC78_001694"
     CDS             5234..5428
                     /locus_tag="VXC78_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0583724.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRKLFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(5794..7104)
                     /locus_tag="VXC78_001695"
     CDS             complement(5794..7104)
                     /locus_tag="VXC78_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV0583725.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7341..8213
                     /locus_tag="VXC78_001696"
     CDS             7341..8213
                     /locus_tag="VXC78_001696"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV0583726.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            8344..9190
                     /locus_tag="VXC78_001697"
                     /pseudo
     CDS             8344..9190
                     /locus_tag="VXC78_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            9276..10226
                     /locus_tag="VXC78_001698"
     CDS             9276..10226
                     /locus_tag="VXC78_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0583727.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYDDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPISLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            10403..11410
                     /gene="gap"
                     /locus_tag="VXC78_001699"
     CDS             10403..11410
                     /gene="gap"
                     /locus_tag="VXC78_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV0583728.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(11477..12313)
                     /locus_tag="VXC78_001700"
     CDS             complement(11477..12313)
                     /locus_tag="VXC78_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0583729.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            12439..14634
                     /locus_tag="VXC78_001701"
     CDS             12439..14634
                     /locus_tag="VXC78_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0583730.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQSLAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            14687..14839
                     /gene="rpmG"
                     /locus_tag="VXC78_001702"
     CDS             14687..14839
                     /gene="rpmG"
                     /locus_tag="VXC78_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0583731.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            14849..15025
                     /gene="secE"
                     /locus_tag="VXC78_001703"
     CDS             14849..15025
                     /gene="secE"
                     /locus_tag="VXC78_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV0583732.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            15080..15616
                     /gene="nusG"
                     /locus_tag="VXC78_001704"
     CDS             15080..15616
                     /gene="nusG"
                     /locus_tag="VXC78_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV0583733.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            15738..>15955
                     /locus_tag="VXC78_001705"
     CDS             15738..>15955
                     /locus_tag="VXC78_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0583734.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWEQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIR"
BASE COUNT         5013 a         2777 c         3207 g         4958 t
ORIGIN      
        1 gatagagttg tttacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaacg agaaaacgat gacaaggtgt gttgcttttt
      121 gatttctaaa gagtataatg atagatctct ataaaataag tgcgaaggaa atgagctttt
      181 ataatccttt cgttttaaaa tactatctca gatattctta tatcgacaag aagtttttga
      241 gtcattccct catcatacat attaaataaa tagtggctca ttcaattttt tactagaata
      301 ataagctagt atagtaaact gaaataagat ataaacaaat aaattggagc ttaacatcta
      361 tttccagcaa ttttttagaa actgcagtgg actattctaa attcaacaca ttataaaaac
      421 tagagtaaaa gaaaaggatt ggatcttgtg taatgcagga tccaatcctt tcaatcattt
      481 tgtccaactt ttggaggttc ctacaatgta gccgtcatta ataaagacag atgggaatga
      541 cagtgttcct atttattttg atagagatcg atgaattctt tagatagcaa ctgaataatc
      601 tctgttgaag ccatttggtc ttctgcatgc ataaatagca aggagaatcc tattttttct
      661 ccagtagctt ctttttgtat gagattagag tgaatcttgt gcgcttctac taaggagtct
      721 tccgcttctt caactttaat tttcgcttct tttaaatttc ctgccttagc tagttggatg
      781 gcttcaataa aggatgattt ggctgctcca ctattggcaa tgagctgaaa acagatatat
      841 tccatttctt ctgtcatctt atttctccta tccatgcaag tgcttgttcc agaacttttg
      901 ctccattcat cattccgtaa tcccgcatat caatggtatc tacagggata tttcctgcaa
      961 tttctttcac agcaagtaac tcataacgaa tttgtggccc aattagaatg acatctgctt
     1021 catggatatt ctttttagct tctgtcattg attttgcttg gatagaaatt tcaatcccac
     1081 gttcagtcgc actttgttgc atttttttaa caagcatact tgtcgacatt cccgcattac
     1141 atactaataa aatttgtttc ataatcttaa ccttccattt cttgttcaac aactttgtca
     1201 ttaactttga taaatggaat gtatagaaga actccaagtg caaagatgat gaattgaact
     1261 agaactgctc tcacgtcccc tgctgttgct aaccatgcat ttaagaatac tggtgtagtc
     1321 caaggaactt gtataaatgc aggactcatg aatcctgtaa ctgttgctaa gtagctgatt
     1381 aaaataccaa ggactggaac tgtgataaat ggaatagcta atgaaatgtt ataaacgatt
     1441 gggtaaccga ataatactgg ttcattgata ttgaagatac caggtccaaa agataattta
     1501 gccacgtttt tagagacagc attgcgactc actaagaatg ttgctattaa taaacataat
     1561 gtagatccac taccacccat taaagcgaat gtttgtattt gtgataggtt gatgatgtgt
     1621 ggaatggctt gtccattatt tgctgcagtg atgttttcag taatgttaat taatagtaat
     1681 ggttctagga tggcactgta aataactgct tggtgaatac caaatagcca taacatattt
     1741 cctaaagagt aaataataat gaccccgatt aagcttgtac caatatgacg aattggttct
     1801 tgaataaaga ttgtaatgat tgagattaag ttcattccag ttatattgaa taataatgct
     1861 gaaacaaccc caaataagga gatgacggtc atgactggaa gtaatacgct aaatgatcta
     1921 ctaacagctg gtggaatatt ttcaccaagg ttcatttgta aagctttaac gtttgataat
     1981 tcaatgaata attctgttgc aataatcgct acgataaccc cggcgaacat tgcgcctgta
     2041 cctgtgttgt tgaatgaaag aacacctgaa atgtttaccg catcttttgc tccgtcagga
     2101 actacagaaa ctgtatttgg catcatcaca attaaagaaa ctaatgatag cattgatgct
     2161 gctaacgggt tttcgaaatc tctgttttta gctaagaaat aaccaaccat tacagcaata
     2221 atcatacctg aaatacttaa agtaccgttt gcaattgtta ttccccaata ttggaatctt
     2281 gttaatgtat ccccttggaa aatccactta aataccgtgt tgttcaaaag aacgattaaa
     2341 cctgccaaaa tatataatgg cattactgtt acgaatgcat ctcttagggt ttttaaatga
     2401 atttggttcc ctagtttacc agcaaaggtg gcaaattgat ctataaattt tgagtttttc
     2461 atctgaatat ctcctctctt tactcctcaa tttctacttc aaaaccgtta ttgtcactta
     2521 ctttgcgata ccatcttcct gatctcttga tggttctctt ttgcgtttct aaatcaacgg
     2581 agataaatcc gtaacgattc ttatatgcat tattccaaga ccagcaatca aatgcggtcc
     2641 aagcgtggta tccaaaacag tgacttccct cttcaatggc tttatgtagc catcttaaat
     2701 gttcttcata aaattcaata cgatacacgt catcgataac tccattttca ccgataaacc
     2761 gtgcttcgtt ttcaacaccc attccgtttt cactgataaa ccatgggata ttaccatatt
     2821 cttccttcac aatcatagca atatcataaa tggctttcgg aaaaatttcc caaccacgat
     2881 atggattcat gcgacgctcc ggccattcat actctttgaa gtattggtct ggcatccagg
     2941 gcgtctgata ttcctcagga tttgcttgtg cttgaacacg ttttggatgg tagtagttta
     3001 ctccaagaaa atcaaccgta tttgatttca tcagttgaag ctctttttcg gtatgactcc
     3061 ataacacgcc atctctctct agctgtttta ccaatctttc tgggaaagtt cctttaacag
     3121 ctggattcaa gaagactttg ttaaagaagt catctgtaaa tcgacttgct tctaagtctt
     3181 ctggagaatt acttcttgga taagcaggtg tcaagtttaa aataatccca atctttccat
     3241 caagtcctaa tgagcgatat agttgaatca cttttgcact agcaaggttt agattataga
     3301 tgacttgtac ggcctctttt ccctttcctt ttagatttgg ataatggaaa gcatataagt
     3361 atcctgcttc tggaatgacc attggctcat tgaaagttgt ccagtaatga accttatctc
     3421 caaagcatgt gaaagcagtc ttggcaaact tcacgaataa ctccactaca tgtttgcttt
     3481 cccaaccacc gtatttttga agaagttcca ctggtaaatc aaaatgatgt aaattcatca
     3541 caagatccat ctggttcttt ttagcttctt caatgatggc attgtagaaa gcaatacctt
     3601 ttggatcagg ctcacctgtc tctaaattct tgatgagtcg actccattgg atggaagtgc
     3661 ggaaagaatt aactccaatt tccttcatca agtggaaatc ttcggtgtaa gtatgaaaaa
     3721 agttactggc tacaagaggt ccgacattat cgaaaaaatc ttctggatgc gttttgaacc
     3781 agtagtccat cacattttca tgtacttttc catattgacc ttctgtctga ggtccgctag
     3841 aagcagctcc ccaccaaaac agattaggaa atactaactt ttttttcatg ctcaacctcc
     3901 tttctattat tctatacata aagtatagca taattttaaa atttgtctag acatttttaa
     3961 aaattgttga tacatatctt gtgtttgcct catttcttga actttgttat actactatta
     4021 gaatattata gagagaacca gattaaatga gtacaaaata tttatttatt tacaatgaga
     4081 ttcgtgaaaa gattctttgt aataaatata ccatgaacga acaattgcct gatgaaatga
     4141 cattagctaa acagtttgcc tgtagtcgaa tgacgatcaa aaaagcttta gacttgttag
     4201 tttctgaggg cttaattttt agaaaacgtg ggcagggaac ctttgttctc tctcgtggca
     4261 gctcaaaaag aaaattaatc gttccagaaa gagatatccg gggattgaca aaaatatctg
     4321 aagatgctca ttctacaatt gactcgagga ttattcactt caaattagaa tttgcaaatg
     4381 aatttttagc agaaaaacta caggtcgctt tgcagagtcc agtttataat atttaccgcc
     4441 tgcgtattat tgacggtaaa ccttatgttc tggaacaaac ttatatgagt accgatgtta
     4501 ttccaggtat tactgaagat attttacaaa aatcgattta caattacatt gaaggaaagt
     4561 taggattgca tattgccagt gctacaaaaa tcttgcgagc ttcttctagt tcagaaaatg
     4621 agcaacatta cttacagctc cttccaacgg aaccggtatt tgaagtagaa caagtggctt
     4681 atttggataa cggaactccg tttgagtact cgattagtcg tcatcgctat gatttatttg
     4741 aatttaattc ttttgcatta cgacattcct cctaggagaa aatgtgaaaa tgaagccaat
     4801 cttttacaga ctctagttta agaaaaattt aaaacagggc aagaaggtcc catctatgct
     4861 taaatggttt ctcttttcta aataagatgg ctttaaaaga gtgatcgttg tatccatcat
     4921 gttgaaaaat atcttcgtat agcttataga gtaggtactg aaattgttca cctgatctac
     4981 ttcttatagt tatttagttt taaatagtgt ttcaaacatt cttacactga cgagaagttt
     5041 ttgagtcttt tcttgtaaca catatagtat actgtggtta gaatagtaga ctgtgacttc
     5101 taacaaattg ctagaaatga atttcaatct cccaatttat ttgttcatat cttcttttaa
     5161 tatattaaat aaattctaaa tcataatcat ttaaaaaaat tttatttttt atttttcatt
     5221 acgaataata tagatgaagg ggaaagagta tgaaaacaga actgtttctt ttgctattag
     5281 ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc atcgtaaatt
     5341 gtttgataat atttcttttg atacttcgag ttcagacgtg acattaatta ctggtaaaaa
     5401 tggtacagga aagtcaactt tactatagta gattgaaact agaatagtac acatctactt
     5461 ctaaaatatt gttagaaatc gatttgacta tcctgatcta tttgtcctgt tcttatttca
     5521 tttcactata tctcaaattg agtatgacga agtgcgctcc catgtcctgg gaacgcactt
     5581 tcttcatatt tttcatattc ttgaatccat cgataaagac tattgggatg aatttttaaa
     5641 gttgaactaa tcatttttac aggatgagat ttacagcaga gagtttgaag gctttatcaa
     5701 aggtttttct tggcataatg acttttcctc gtttccactt aattttgtgt ctactttatt
     5761 ataccaagtc cactcttaag ttagataata aatctaactt aaggaagcta gaaggatgag
     5821 aatccaggtg gtcaagagtc ccaaacttaa gctgatgggg acacccagaa taatttgctt
     5881 tttgaaggca aggccacgtt cctctatatt gggaagtgag agttgaatga gagaaccagc
     5941 tgatgaaaag ggtgagatat tagtagatag agcgccaata acggtggctg ttgtgagtaa
     6001 gtgaatatca atctgaggat tttgagcact gatgatagca atgatgggaa agagggctgg
     6061 agctacaacg gatagggtgg aactaaagag tgacatcact ccggctatca cacaaaagaa
     6121 cagaggtaac cagaaatgag gaatggttgt tgtcatgagg tgccctatca gtgtgactaa
     6181 acctgacttg accgctagag acattagtaa gctcatgccg cagagcatga taattgtagc
     6241 ccagggaacc ttagctaaaa tggcttcttg cttccctaat ttgagcctta aggcgaggca
     6301 gaccatgagt attgagacaa agccaatatc aaatgttttt tgataagtag ctatccaggc
     6361 gatgtttggg aaaatgagat gcaacaaggg aaaaagccaa accaaaacca tgctgctgat
     6421 catgagcaag gtggtttgtc tttgaacctt gctgaggagt ggtggttggt caatagtcaa
     6481 ggatgagttt gttcttccct tactatagtg actgtaacag gataataaaa gcaagacgat
     6541 gagtgggtag ataatgctga cgataaagat atgattgcca agtgaaaaag cttgctcttc
     6601 ccatcccatt tgcttaaaca ggccttgaaa gacaatgcct gagctactgg ttatcaaatt
     6661 agcccctcct gaagctcccc aattgacggc ttgagctcca atcaaagggt gtttgtccgc
     6721 tttttgacag agggtaatcg ctagaggaca gcaaacggcc atagtagtga aaaatccagc
     6781 acctaaagca gacaaaaggg ttgccatcag gtataaaatc atgtagaggg cgttagggtg
     6841 ggtgcgtgtg cggtagagaa tgtgttgagc caaaacatca agagtaccgt tagttgttgc
     6901 aacgttataa aagagagaga cactaaaaat ggtaaaaaag agtgaggttg gccaaaaatg
     6961 aagaagttct ttggggctta atcccatgag agtggttgcg atgaggtaag aaaaagcaat
     7021 agccagcagg ccaatattga ttttggtgcg gtaaccaatt ccaatggcta gagcaatggc
     7081 gctaatcatt attaaatgaa tcattgaatt gtcctttcag ttagaatatg gaaataggtt
     7141 ggcaattttg gcgctcaaaa gaccacctgt ttcctattgg tacttgacta ttatacacaa
     7201 aaaaaataca attgtcttga caattgtatt gacacttgtt agaattaaaa atgaggtatt
     7261 caggcttgtg atttcctatg gaagttaata gtaattgcct ctagtgctta caagtgatat
     7321 taaaaataga ggacttagtg atgtcaatca tttcaactga tttaacccct tttcaaatag
     7381 atgatacatt gaaagcagcc ttgcgagaag atgttcattc cgaagattac agtaccaatg
     7441 ccatttttga tcatcatggc caagccaagg tgtcgctttt tgccaaggaa gctggtgttt
     7501 tagcgggact aaccgttttt caaagggttt ttaccctatt tgatgccgag gtgaccttcc
     7561 agaatcctca tcaatttaag gatggggatc gtttgactag tggcgatttg gttttagaaa
     7621 tcataggctc ggtgagaagt ctcttaacat gtgaacgcgt tgccttgaat tttttacaac
     7681 atttatcagg gattgcttcg atgacagctg cttatgtaga agccttaggc gatgattgca
     7741 ttaaggtatt tgatactcga aaaactactc ctaatttacg tctttttgag aaatatgccg
     7801 tgagagttgg cggtggctat aatcatcgct ttaatttatc agatgctatc atgctaaaag
     7861 acaatcacat tgcggcagta ggtagtgttc agaaggcaat tgctcaagcg cgtgcctatg
     7921 ccccttttgt gaaaatggtc gaggtggaag tggaaagcct tgctgctgcc gaagaagctg
     7981 cggcggcggg tgctgatatt atcatgttgg ataatatgtc attggaacag attgaacagg
     8041 ccattaccct aattgcagga cgttctcgga ttgaatgttc tggaaatatt gatatgacca
     8101 ctattagccg ttttcgtggt ttagcgattg attacgtctc cagtggtagt ttaacccata
     8161 gtgctaagag tcttgatttt tccatgaagg gtttaaccta ccttgatgtc taagttgtaa
     8221 aataaactaa ctttttaaag gatgtctttc ctctagaacg agttttatgt cagatagttt
     8281 aaacgcctct tcaaatatag taaaatgaac caaaaatagt acacaatgtg gtataatctt
     8341 cttatggcat attcaataga ttttcgtaaa aaagttctct cttattgtga gcgaacaggt
     8401 agtataacag aagcatcaca cgttttccaa atctcacgta ataccattta tggctggtta
     8461 aagctaaaag agaaaacagg agagctaaac caccaagtaa aaggaacaaa accaagaaag
     8521 gttgatagag atagacttaa aaactatctt actgacaatc cagacgctta tttgactgaa
     8581 atagcttctg aatttgcctg tcatccaact accatccact atgcgctcaa agctatgggc
     8641 tacactcgaa aaaaagaacc acacctacta tgaacaagac ccagaaaaag tagccttatt
     8701 tcttaaaaat tttaatagtt taaagcacct agcacctgtt tagattgatg aaacaggatt
     8761 cgatacttat ttttatcgag aatatggtcg ctcattaaaa ggtcagttaa gaagaggtaa
     8821 agtatctgga agaagatatc agaggatttc tttggttgca ggtctaacaa atggtgagtt
     8881 aatcgctcca atgacttacg aagagatgat gacgagcgac ttttttgaag cttggtttca
     8941 gaagtttctc ttaccaacat taaccacacc atcggttatt attatggata atgcaagatt
     9001 ccatagaatg ggtaagttag aacttttatg cgaggagttt gggcataaac ttttacctct
     9061 tcctccctac tcacctgagt acaatcctat tgagaaaaca tgggctcata tcaaaaagca
     9121 cctcaaaaag gtattaccaa gttgcaatac cttttatgag gctcttttgt cctgctcttg
     9181 tttcaattga ctatagttca cggatacagt tgggaaagaa gctattaaat atttggagag
     9241 tccttttggg atgaacatgt caaatattac tatagatggg caagaaaaga tgggcaagaa
     9301 atggatctga gtcaaacgat gcttcttatg ctcaagtagt gagtctttat gatgatacaa
     9361 gtatctctgt tagtaataat gagacggaca aagtgttgac tggatccctc tatactgaaa
     9421 caaatgaaca gggattaacg attccaatca gtttactaaa aaattggaat gaacagacag
     9481 gaaaaaattt gacaactaat gatcttattg gcaaatcagt ctcagccagc attgtagaaa
     9541 gtgctgccga aactagtaag attgctcaat ttcaaacgaa gattgtacgt gtaatcaatg
     9601 atgaagatga catggaggac agcaacagtt tcatgctgtc tcatcaaatg gaaacgattt
     9661 tgaaagaggc tggatttacg aaagctgtat cttattttat cttggaactc aaagatccat
     9721 cacagacaaa agtagtaaca gaagaattac agaaaaataa gaagtatact gtgctttctc
     9781 aacagagagt tcttgatatt gtgattacct ttattcgtgt tattcaggga ttattgattg
     9841 tgctttcatc acaagctatt gtggtagcag cggttatgat tggtatcatt atttacatca
     9901 atatcatgca acgttccaag gaaataggtg tcatgaaagc agttggttat cagaatcgtg
     9961 gtgtcaaagg aatttttatt tacgaggcta tctggattgt aggcatcgcc ttgctgctgg
    10021 catttttggt tgcacaaggg gtgggaagtt tggcgaatgc gattgtaagt cacttttacc
    10081 catccatcac taaggttttt gaattaaatc ttttatctgt tttaggaact ctagttttcg
    10141 ctctattact tggttatgtc tcagcctact tcccggcgcg taagattagt aaaatggatc
    10201 ctgtagaatc gttacgctat gaataataag ggattccttg atttacagtc ttaaaaagaa
    10261 actcacatag aaaaacaatg gccatacttg caattcaact caaatagttg tataataggt
    10321 ttgttgaaag gtgatttgta gtgattcaag ttactctttt cacaataaaa atttcatgat
    10381 tttcataagg aggaaatcac taatggtagt taaagttggt attaacggtt tcggacgtat
    10441 cggtcgtctt gctttccgtc gtatccaaaa cgtagaaggt gttgaagtta cacgcatcaa
    10501 cgaccttaca gatccagtta tgcttgcaca cttgttgaaa tacgacacaa ctcaaggtcg
    10561 tttcgacggt actgttgaag ttaaagaagg tggattcgaa gttaacggta aattcgttaa
    10621 agtttctgct gaacgtgatc cagagcaaat cgactgggct actgacggtg tagaaatcgt
    10681 tcttgaagct actggtttct ttgctaagaa agaagcagct gaaaaacacc ttaaaggtgg
    10741 agctaaaaaa gttgttatca ctgctcctgg tggaaacgac gttaaaacag ttgtattcaa
    10801 cactaaccac gacgttcttg acggtactga aacagttatc tcaggtgctt catgtactac
    10861 aaactgcttg gctccaatgg ctaaagctct tcaagataac tttggtgttg ttgaaggatt
    10921 gatgactact atccacgctt acactggtga ccaaatgatc cttgacggac cacaccgtgg
    10981 tggtgacctt cgccgtgctc gcgctggtgc tgcaaacatc gttcctaact caactggtgc
    11041 tgctaaagct atcggtcttg taatcccaga attgaacggt aaacttgacg gatctgcaca
    11101 acgcgttcca actccaactg gatcagttac tgaattggta gcagttcttg aaaagaacgt
    11161 tactgttgat gaagtgaacg cagctatgaa agcagcttca aacgaatcat acggttacac
    11221 agaagatcca atcgtatctt cagatatcgt aggtatgtct tacggttcat tgtttgacgc
    11281 aactcaaact aaagttcttg acgttgacgg taaacaattg gttaaagttg tatcatggta
    11341 cgacaacgaa atgtcataca ctgcacaact tgttcgtact cttgaatact tcgcaaaaat
    11401 tgctaaataa ttcttgagtt gatagaaagc aaggctttgt ggtcttgctt tttatataga
    11461 aaaatggatg acacgatcat ccattctttt ttaattcttt ttcaaatgta tttgaaaggg
    11521 tagtgaaagt tagcttttct aaagtaagtg ggtgggtaaa ggaaagtcgg aaggcatgaa
    11581 gcataagccg acttgtcttt gatttactat tatagagagg gtcgcccagg ataggaagat
    11641 tatgatgcga aaggtgcaca cgaatctgat gggttcgccc tgtctttagc ttgcaacgag
    11701 ccaaggaagt cttgtttgag aattgcttta atctgcttac atacgtttca gcatattgcc
    11761 cattttttgc atcaactatt ctttttctac gatcatggcg atcacgtcca attttgtctc
    11821 tgaaaacaag ttcttttctg ttgatatttc catcaactag agcccaatat tctctagaaa
    11881 tctctttttt ctccaataag cgattgagaa tgggcaggat aaaaggattt ttggcaaaga
    11941 gaactaagcc actggtttcc atgtccagac gatgaacgac atagcaggtt tggccaacat
    12001 aggtactgac atggttaaga agggcaattt cgtttggttg attaccatgc gttttcatcc
    12061 cctctggttt gtttacaata atcaagtgtt gatcttgata aacttcctgc actaagtctg
    12121 ggttgcccca agggatcgtc ttttggggat aatcttcctc gtcaaaagtc aactggcaaa
    12181 catctccagg atttacgatt tcgttccagt ggacttcttc ttgatttatc aaaatatgtt
    12241 tcttgattct caaaaaatga cggatttttc tagggatgag gagttgttcc tcaagtaatt
    12301 gctttaccgt catttgaggt atagaggcgg gtaatgtaaa tgtgaattgc atacagatat
    12361 tgtaacaaaa aaagccctat ttggatagga aatagctaaa ttcttgtctt cctatgatga
    12421 agatgataaa ataaacgcat gaaattagat aaattatttg agaaatttct ttctcttttt
    12481 aaaaaagaaa caagtgaact agaggactct gattctacta tcttacgtcg ctctcgtagt
    12541 gatcgaaaaa aattagccca agtaggtccg attcgaaaat tctggcgtcg ttatcatcta
    12601 acaaagatta tccttatact aggtttgagt gcaggcttgc tagttggaat ctatttgttt
    12661 gctgtagcca agtcgaccaa tgtcaatgat ttgcaaaatg ccttgaaaac tcggactctt
    12721 atttttgacc gtgaagaaaa agaggctggt gccttgtctg gtcaaaaggg aacctatgtt
    12781 gagctgactg acatcagtaa aaacttgcag aatgctgtta ttgcgacaga agaccgttct
    12841 ttctataaaa atgacgggat taactatggc cgtttcttct tggctattgt cactgctgga
    12901 cgttcaggtg gtggctctac cattacccaa cagctggcta aaaacgccta tttatcgcag
    12961 gatcaaactg ttgagagaaa agcgaaagaa tttttccttg ccttagaatt aagcaaaaaa
    13021 tatagtaagg agcaaattct aaccatgtac cttaacaacg cttattttgg aaatggtgtg
    13081 tggggtgtag aagatgcgag taagaaatac tttggagttt ctgcatcaga agtgagtctg
    13141 gatcaagctg cgactctggc agggatgctc aaggggccgg aactgtataa tcccttgaat
    13201 tccgtagaag attctactaa tcggcgcgat actgtcttgc agaatatggt tgcagcagga
    13261 tatattgata aaaaccaaga aaccgaagct gctgaagttg atatgacttc gcaattgcac
    13321 gataagtatg aaggaaaaat ctcagattac cgttatccct cttattttga tgcggtggtt
    13381 aatgaagctg tttccaagta taatctaaca gaggaagaga ttgtcaataa tggctaccgc
    13441 atttacacag agctggacca aaactaccaa gcaaatatgc agattgttta tgaaaacaca
    13501 tcgctatttc cgagggcaga ggatggaacg tttgctcaat caggaagtgt agctctcgaa
    13561 ccgaaaacag ggggagttcg tggagttgtc ggtcaagttg ctgacaatga taaaactgga
    13621 ttccggaatt tcaactatgc aacccaatca aagcgtagtc ctggttctac aattaagcct
    13681 ttagttgttt atacaccagc agttgaagca ggctgggctt tgaataagca gttggataac
    13741 cataccatgc agtatgatag ctataaggtt gataactatg cagggatcaa aacaagtcga
    13801 gaagttccta tgtatcaatc cttggcagaa tcgcttaatc tacctgctgt tgccactgtt
    13861 aatgatttgg gtgttgacaa ggcttttgag gcaggcgaaa aattcggact caacatggaa
    13921 aaggtcgacc gtgttcttgg tgtcgccttg ggaagcggtg ttgaaaccaa ccctcttcaa
    13981 atggctcaag catacgctgc ctttgcaaat gaaggtttaa tgcctgaagc tcattttatt
    14041 agtagaattg aaaatgctag tggacaagtt attgcgagtc ataaaaattc acaaaaacgg
    14101 gtgattgata agtctgtagc tgacaagatg accagtatga tgttggggac tttcaccaac
    14161 ggtaccggta ttagttcatc gcctgcagac tatgtcatgg cagggaaaac tggaacaact
    14221 gaagcagttt tcaatccgga gtacacaagt gaccagtggg taattggtta tactccggat
    14281 gtagtgatta gccactggct tggctttccg accactgatg aaaatcacta tctagctggc
    14341 tctacttcaa acggtgcagc tcatgtcttt agaaacattg ccaataccat tttaccttat
    14401 acgccaggaa gtacctttac ggttgaaaat gcttataagc aaaatggaat tgcaccagcc
    14461 aatacaaaaa gacaagtaca aaccaatgat aatagccaga cagatgataa tttgtctgat
    14521 attcgagggc gtgcgcaaag tctagtagat gaggctagcc gggctatctc agatgcgaag
    14581 attaaggaaa aggctcaaac aatatgggat tcgatagtca atctatttcg ctaagatgct
    14641 tgtcaaagcc tagctttctt gttataatgg ataagatgga ggcgttatgg cactaaaaaa
    14701 agcaagccta gcttgtgcgg tttgtggttc gagaaactat tcaatcaaga tcagcggaaa
    14761 ccccaagcct acacgactag aagtaaataa attttgtaag cattgtggca agtacactac
    14821 acacagagaa acgagatagg agagagcgat gcgttttatt ggagatattt ttagacttct
    14881 taaagacaca acatggccaa ctcgcaagga aagctggaga gattttcgtt ctatcatgga
    14941 atacacagct ttctttgtag taattattta catttttgac cagttgattg tttcaggttt
    15001 gattcgattt attaacattt tttagaagat tagtggagtt aattacacta gaaatcttct
    15061 atttatgaaa ggaaatatca tggatagttt tgataaagga tggtttgttt tacaaactta
    15121 ttctggttat gaaaataagg tgaaagaaaa tctattacaa cgtgcacaaa cctacaatat
    15181 gttggataat attctacgcg ttgaaattcc aacacaaaca gtgcaagttg aaaaaaatgg
    15241 aaagagaaaa gaagtagaag aaaatcgctt tccaggttat gttcttgtag aaatggtcat
    15301 gacagatgaa gcttggtttg ttgttcgaaa cacaccaaat gttacaggat ttgtcggatc
    15361 acacgggaac agatcaaaac caactccatt attggaacaa gaaattcgtg acattttggt
    15421 atctatggga caaactgttc aagaatttga tttcgatgtt gagattggtc aaactgtacg
    15481 tattattgat ggtgcttttg cagactacac tggtaagatt acagaaattg ataataacaa
    15541 agtgaaaatg attatctcta tgtttggtaa tgacacagtt gcagaagtaa acctaaacca
    15601 aatcgcagaa ttataaccct gagagaggct ggagcctctc ttttttgtgc agtttaggag
    15661 ctaaagggaa cagaatggag aaaatggaac aaatgtgttt tctaatctgt tagactgtat
    15721 ctagaaaggg gaaaattatg attaaagaat tgtatgaaga agtccaaggg actgtgtata
    15781 agtgtagaaa tgaatattac cttcatttat gggaattgtc ggattgggag caagaaggca
    15841 tgctctgctt acatgaattg attagtagag aagaaggact ggtagacgat attccacgtt
    15901 taaggaaata tttcaagacc aagtttcgaa atcgaatttt agactatatc cgtaa
//
LOCUS       DAVLCS010000043        15164 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLCS010000043 DAVLCS010000000
VERSION     DAVLCS010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15164
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.043"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            6..416
                     /locus_tag="VXC78_001706"
                     /pseudo
     CDS             6..416
                     /locus_tag="VXC78_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            454..756
                     /locus_tag="VXC78_001707"
     CDS             454..756
                     /locus_tag="VXC78_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0583735.1"
                     /translation="MIKILAACGAGVNSSYQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGSILFRIPAMSAPVFDNIILPAKQNMV"
     gene            764..1567
                     /locus_tag="VXC78_001708"
                     /pseudo
     CDS             764..1567
                     /locus_tag="VXC78_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1616..2080
                     /locus_tag="VXC78_001709"
     CDS             1616..2080
                     /locus_tag="VXC78_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV0583736.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2237..2662
                     /gene="lacA"
                     /locus_tag="VXC78_001710"
     CDS             2237..2662
                     /gene="lacA"
                     /locus_tag="VXC78_001710"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV0583737.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2693..3208
                     /gene="lacB"
                     /locus_tag="VXC78_001711"
     CDS             2693..3208
                     /gene="lacB"
                     /locus_tag="VXC78_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV0583738.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3219..4148
                     /locus_tag="VXC78_001712"
     CDS             3219..4148
                     /locus_tag="VXC78_001712"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV0583739.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLTKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            4150..5130
                     /gene="lacD"
                     /locus_tag="VXC78_001713"
     CDS             4150..5130
                     /gene="lacD"
                     /locus_tag="VXC78_001713"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV0583740.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5364..6200
                     /locus_tag="VXC78_001714"
     CDS             5364..6200
                     /locus_tag="VXC78_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0583741.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6236..6553
                     /locus_tag="VXC78_001715"
     CDS             6236..6553
                     /locus_tag="VXC78_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0583742.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6553..8244
                     /locus_tag="VXC78_001716"
     CDS             6553..8244
                     /locus_tag="VXC78_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0583743.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGASVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAKYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            8459..9865
                     /gene="lacG"
                     /locus_tag="VXC78_001717"
     CDS             8459..9865
                     /gene="lacG"
                     /locus_tag="VXC78_001717"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0583744.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSFNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGKKGSSKYQIKGVGRR
                     VAPDYVPRTNWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9908..10165
                     /locus_tag="VXC78_001718"
     CDS             9908..10165
                     /locus_tag="VXC78_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV0583745.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(10444..11205)
                     /locus_tag="VXC78_001719"
     CDS             complement(10444..11205)
                     /locus_tag="VXC78_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0583746.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(11493..12455)
                     /gene="nrdF"
                     /locus_tag="VXC78_001720"
     CDS             complement(11493..12455)
                     /gene="nrdF"
                     /locus_tag="VXC78_001720"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV0583747.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(12643..14802)
                     /gene="nrdE"
                     /locus_tag="VXC78_001721"
     CDS             complement(12643..14802)
                     /gene="nrdE"
                     /locus_tag="VXC78_001721"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV0583748.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(14883..15101)
                     /gene="nrdH"
                     /locus_tag="VXC78_001722"
     CDS             complement(14883..15101)
                     /gene="nrdH"
                     /locus_tag="VXC78_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV0583749.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPEKLKQLA"
BASE COUNT         4714 a         2731 c         3095 g         4624 t
ORIGIN      
        1 aataactctt tgatcaggta gcaagcttgt tggaggaacg agaaattgta actccaactt
       61 atcgtgaagc tttgatcacg cgtgaaaagt catttccaac tggtttagat atggaatttc
      121 taggaaagga cttgccaaat gtagcgattc ctcacacaga tattgttcat aatctagctg
      181 aaaaagtggt ggttgttcga ttagaaaaac cagtaacttt tcacaatatg atagctcctg
      241 ataaggaagt agaagtatcc ctactcttct ttatcattaa caattcaagt tcaagtcaaa
      301 caaatattct ggctcagttg atggactttt tcacaggaaa tggacatctt gaagatttat
      361 caaaaatttc cgaaccagaa aaactttatg cttacattgc tgaagcaatc gcttaatctt
      421 gtctattaaa aaataaaatc ggaggaaatc caaatgatta aaattcttgc tgcctgcggt
      481 gcaggtgtta actcaagtta ccaaattaaa agtgctctag aagaagaact ttcaaaccgt
      541 ggttatgatg ttcactgtga tgcagtcatg gtgaaagatg taaacgaaga ccttatgaaa
      601 ggttacgata tctttacacc aatcgctgca acagatcttg gttttgaacc aggtatccca
      661 gttatcgaag ctgggtcaat cttattccgt ataccagcaa tgagcgctcc agtatttgac
      721 aatattatac ttcctgcgaa acaaaatatg gtatagtagt tctatgaatg atgaagcaag
      781 taaacaacta actgatgcac gatttaagcg tcttgttggt gttcagcgta ccacttttga
      841 agagatgtta gctgtattaa aaacagctta tcaacttaaa cacgcaaaag gtggacgaaa
      901 acctaaatta agcctagaag accttcttat gcccactctt caatagtgcg agaataccgc
      961 acttatgaag aaattgcggc tgattttggt attcacgaaa gcaactttat ccgtcggagc
     1021 caatgggttg aaataactct tgttcaaagt ggttttacgg tttcaagaac tcctctcagt
     1081 tctgaggaca cggtaatgat tgatgcgacg gaagtaaaaa tcaatcgccc taaaaaaaca
     1141 attagcgaat gattctggta aaaagaaatt tcacgctatg aaggctcaag agattgtcac
     1201 aagtcaaggg agaattgttt ctttggatat cactgtgaac tattgtcatg atatgaagtt
     1261 gttcaaaatg agtcgcagaa atatcggaca agctggtaaa atcttggctg acagtggtta
     1321 tcaagggctc atgaagatat atcctcaagc acaaactcca cgtaaatcca gcaaactcaa
     1381 gccgctaata gctgaagata aagcctataa ccatgcgcta tctaaggaga gaagcaaagt
     1441 tgagaacatc tttgccaaag taaaaacgtt taaaatgttt tcaacaacct atcgaaatca
     1501 tcgtaaacgc ttcggattac gaatgaattt gattgctggt attatcaatc ataaactaga
     1561 attctagttt tgcaggaagt ctaataaaga aactagcaag gtcaggcctt actttattgg
     1621 tggacatcca ggatttaatt gtcttctact tgatgatgaa gtctatgaag attattatct
     1681 agagtttgag aaagaagaga tttgctctgt tccacgtcct ttcccagaaa caggtatgtt
     1741 ggatttccaa gatagaagtc catggctaga gggacaaaaa gaaatagatc ttagttatga
     1801 tcttttcagc acagatgcag tgactttgga tgaattgcaa tctcgaacaa ttgcccttcg
     1861 ttctcttaaa catgataagg gattgaaagt gcattttgca gaatttccaa acctcatcat
     1921 ctggtcaact ttgaacaagg gacctttcat tacctttgaa ccatggtctg gcttgtcaac
     1981 attccttgaa gaaggagatc atttagaaga taagaagaat gtttgtctct tagaagccaa
     2041 tcaggttgaa gaattagggt ttgagataga agttttataa aaaagcaaaa aataaataac
     2101 aaaaacaaac acaaactgtt gacttcttca aacaatagta gtatattatg tttgtgagga
     2161 ctaattgact gttttttaaa gacagccaat acactgctgg aatccagcat agaaaaaata
     2221 aaaaggagta tacaatatgt ctattgttat cggtgcagat gctgcaggtt tgagattgaa
     2281 agaagttgtg aaagacttct tagaaaaaga aaacttccac cttgtggatg ttacagctga
     2341 aggtcaagac tttgttgatg tgactctcgc tgttgctgca gaagtaaaca aagaagaaca
     2401 aaaccttggt atcgtgattg atgcttatgg agctggtcca tttatggttg caactaagat
     2461 caaaggaatg gttgctgcag aagtatctga cgaacgttca gcttatatga ctcgtggcca
     2521 caacaactca cgtatgatca ctatgggggc acaacttgtt ggtgatgaat tggctaaaaa
     2581 tatcgctaaa ggatttgtta acggtaaata cgacggtggt cgtcaccaaa ttagggtcga
     2641 catgttgaac aaaatgggct aattagatta tagtaagaaa ggtaagttaa aaatgagaat
     2701 tgcaattgga tgtgaccaca tcgtaacaga tgaaaaaatg gcggtttcag aatttttgaa
     2761 atcaaaagga tatgaagtca ttgactttgg tacctatgac catacacgta ctcactaccc
     2821 aatctttggt aaaaaagtag gggaagcagt aactagtggt caagctgatc tcggggtatg
     2881 tatctgtggt actggtgttg gtatcaacaa cgctgtaaat aaagttccag gtattcgttc
     2941 tgccttggtt cgtgatatga caacagccct ttatgctaaa gaacaattga acgccaacgt
     3001 tatcggtttt ggtggtaaga ttactggtga attgcttatg tgtgatatca tcgaagcttt
     3061 cattcatgct gaatacaaac catctgaaga aaacaaaaaa ttgattgcga aaattgaaca
     3121 ccttgaaagt cacaatgctc aacaaacaga cgcaaacttc ttcactgaat tccttgaaaa
     3181 atgggatcgc ggagaatacc acgactaaga ggtaacctat gattttaaca gttacaatga
     3241 acccatccat tgatatttcc tatcccttgg atgagttgaa gattgatact gtcaatcgtg
     3301 tggtggatgt aaccaaaacg gctggtggta agggactcaa tgttacccga gtactttcag
     3361 aatttggcga ttctgttctt gctactggtt tagtgggtgg caaacttggt gagtttttgg
     3421 ttgaacatat cgataatcaa gtaaagaaag atttcttctc aattcaggga gaaactcgta
     3481 actgtatcgc tattctccac ggagacaacc aaacagaagt tcttgaaaaa ggtcctgaag
     3541 tattggaaca ggaaggtcaa gactttttgg aacatttcaa aaaactcttg gagtcagttg
     3601 aagtagtggc catctcaggt agtctgccag ctggccttcc agttgattac tatgcgagct
     3661 tggtagaact tgctaatcaa gctggcaagc ctgtagtctt ggactgctca ggtgcagcac
     3721 ttcaggctgt tcttgaatca ccccataaac caacagtcat caaaccaaat aatgaagaat
     3781 tgtctcagct tcttggaaga gaagtttctg aggatttgga tgaattaaaa gaagtacttc
     3841 aagaaccttt gtttgcaggg attgaatgga ttatcgtttc acttggtgcc aacggtactt
     3901 ttgccaaaca tggtgacact ttctacaagg tagatattcc tagaattcag gtggtaaatc
     3961 ctgttggatc tggagactct actgtggcag gaatttcttc aggacttctt cacaaagaat
     4021 cggatgcaga attactcacc aaggcaaatg tccttggtat gctcaatgct caagaaaaaa
     4081 tgactggtca tgtcaacatg gccaactatc aagttctata tgatcaatta atagtaaaag
     4141 aggtataaaa tggctttaac agaacaaaaa cgtgtacgct tagaaaaact ttctgatgaa
     4201 aatggtatca tctcagctct tgcatttgac caacgtggtg ctttgaaacg cctcatggct
     4261 caacaccaaa cagaagaacc aactgtggcc caaatggaag aacttaaagt cttggtagca
     4321 gatgaattga ctaaatacgc ttcatctatg cttcttgacc ctgagtatgg acttccagca
     4381 actaaagctc ttgatgaaaa agctggtctt ctccttgctt atgaaaaaac aggttatgac
     4441 acaacaagca caaaacgctt gccagactgc ttggatgtct ggtctgcaaa acgtattaaa
     4501 gaagaaggtg cagatgcagt taaattcttg ctttactatg atgtagatag ctcagacgaa
     4561 ctcaatcaag aaaaacaagc ctacatcgaa cgcatcggtt ctgagtgtgt ggctgaagat
     4621 atcccattct tccttgaaat tcttgcttac gatgaaaaaa ttgcggatgc aggttctgta
     4681 gaatacgcga aagtaaaacc acacaaagtt atcggcgcta tgaaagtctt ttcagaccca
     4741 cgctttaaca ttgatgtctt gaaagttgaa gttcctgtta acattaaata tgttgaaggc
     4801 ttcgctgaag gtgaagtagt ttatacacgt gaagaagcag cagccttctt caaagcgcaa
     4861 gatgaagcaa cgaacttgcc atacatctac ttgagtgctg gtgtatcagc taaactcttc
     4921 caagatactc ttgtatttgc tcatgaatca ggtgcaaact ttaacggagt tctttgtggc
     4981 cgtgctacat gggcagggtc agttgaagct tacatcaaag atggtgaagc agcagctcgc
     5041 gaatggcttc gcacaactgg atttgaaaac attgatgagc tcaataaagt tcttcaaaca
     5101 acagcgactt catggaaaga acgtgtgtaa gaaagtcctc ctagtttagg aacatgaatc
     5161 taaaaaaatt taaaaaaagt tgtatgtaaa ggtttacaaa ataacttact tgtgctatac
     5221 ttaaatcaca agttaataca aggtgagtgt tactaagtaa tattaggcat gatcacaggt
     5281 gaattagaaa tcagctgatt ttctagttca tttgtggtca ttttttgtac ttatatacct
     5341 ttaagatata aaaggaggtt gacatgtatc gaattctaaa tccaatgaat cacaatgtct
     5401 cgcttgtcag aaatgataag ggagaagagg tgattgtaat tggtaagggg attgcattcg
     5461 gaaagaagaa gggggatttg attgctgaaa atcaggttga gaaaatcttt cggatgaaga
     5521 ccgaagagtc cagagaaaac tttatggctc ttctcaaaga tgttccgctt gattttatca
     5581 cagtgaccta tgaaatcatt gataagctat caaagaaata tcattatccg attcaagagt
     5641 atctctatgt aaccttgaca gatcatattt actgttctta tcaagctcta actcaaggaa
     5701 ggtacaagga tagtaatctg ccagatattt ccgctaagta tcctgtcgct tttcaaatcg
     5761 caaatgaagc ttttgaaatt taccgtcaga agctagcaga tcattttcct gaggacgaaa
     5821 ttattcggat tgcttatcat ttcattaatg ctgaaggtga aaatgaagtg gaacttgtgg
     5881 agtcgattga taagaggaaa gaaattctca ggaatgttga agaagtttta acggactatg
     5941 caattcaacg aactaaaaag aataaccatt tctatgatcg ctttatgatc catttgaatt
     6001 atttcttgga ttatttagac agatctagag atgataacca atcacttctg gatatggaag
     6061 atcatattaa acaatcctat ccaaaagcct tcgagattgg ttccaagatc tatgatgtga
     6121 ttacgcaaca tacgggtctt gatttgtata aaagtgaacg agtttatcta gttctacata
     6181 tccaacgttt attgtcataa aaatttattt aaaactatat aaggagaatt ctatcatgaa
     6241 tagagaagaa gtaacattgt taggttttga aatcgtagcc tatgctggcg atgctcgttc
     6301 aaaactattg gaagccttga aggctgctga agctggtgat tttgaaaaag cggacgctct
     6361 ggtagaggaa gctggtagct gtattgcaga ggctcaccac gcgcaaacaa gtctattgac
     6421 taaggaagct tcaggtgagg acttggctta tagtgtaacc atgatgcatg gccaagacca
     6481 cttaatgaca actatcttgt taaaagattt gatgcatcat ttaattgaac tctacaagag
     6541 aggagttaaa taatgaataa actaattgca tttatcgaga aaggaaagcc tttctttgaa
     6601 aaactatctc gtaatatcta tcttcgtgct attcgtgatg gtttcattgc aggtatgcct
     6661 gttattctct tctcaagtat ctttatcttg attgcctttg taccaaactc atggggcttt
     6721 aaatggtctg atgaagttgt agcctttctg atgaaacctt atagctattc tatgggtatt
     6781 ctggctctct tggtagctgg tacaacagct aagtcattga ctgactcagt aaaccgtagc
     6841 atggaaaaaa ccaatcaaat caactatatg tcaacattgt tggcagcaat tgttggtttg
     6901 ttgatgttgg cagctgatcc tatcgaaagt ggtctagcta ctggattctt ggggacaaaa
     6961 ggtttgcttt cagccttcct tgctgccttc gttactgtag ccatctataa ggtttgtgtt
     7021 aagaacaacg tcactattcg tatgcctgac gaagttccac caaatatctc acaagtcttt
     7081 aaagatgtga ttccattcac tctctcagtt gtttcacttt atgctcttga tttactagct
     7141 cgtcattttg ttggtgcaag cgtagctgaa tcaatcggta aattctttgc accactcttc
     7201 tcagcagcag acggatacct tggtattacc attatctttg gtgcctttgc cttcttctgg
     7261 tttgtgggta ttcatggtcc atctattgtt gaacctgcta tcgcagcaat tacctatgca
     7321 aatgctgaag tcaacttgaa ccttctccaa caaggtatgc acgctgacaa gattcttact
     7381 tctggtacac aaatgtttat cgttaccatg ggtggtactg gtgcgacact ggttgttcca
     7441 ttcatgttca tgtggttaac aaaatcaaaa cgtaaccgtg caatcggacg tgcttcagta
     7501 gttcctacct tcttcggtgt aaatgagcca atcttgtttg gtgcacctct tgttttgaat
     7561 ccaatcttct tcattccatt tatctttgct ccaattgcaa acgtatggat ctttaaattc
     7621 tttattgaaa ctcttggaat gaactcattc actgctaatc taccatggac aaccccagct
     7681 ccactaggtc tagttcttgg tactaacttc caagttctat cattcattct tgctgccctt
     7741 ctaatcgtgg ttgacgttgt catttactat ccattcctta aggtctatga tgaacaaatt
     7801 cttgaagaag aacgttcagg taagtctaat gatgaattga aagaaaaagt tgctgcaaac
     7861 ttcaacactg caaaagcgga tgctattctt gaaaaagcag gtgtagaagc agcacaaaat
     7921 acaatcacta aagaaacaaa tgtcctcgtt ctttgtgcag gtggaggaac aagtggtctc
     7981 cttgcaaatg ctttgaataa ggcagcagca aaatacaatg tccctgtgaa agcagcagca
     8041 ggtggctatg gtgctcaccg tgaaatgttg ccagagtttg atcttgttat ccttgcccct
     8101 caagttgctt caaactttga agatatgaag gcagaaacag ataagctcgg tattaaactt
     8161 gctaagacag aaggcgctca atacatcaaa ttaactcgtg atggaaaagg tgccctagca
     8221 ttcgtacaag agcaattcga ttaaggctag gaactgtgaa acagtctccc atcgttacgg
     8281 aaatcgctat ggcgaatttc ctaatcgcct tattaattcg tcggtaaaaa gatatcgttt
     8341 ttacctcctc atgtcacaat tcagtgactt ggcacaagaa gtgagatgga gaagcatggc
     8401 tcactgactc ctctcctctc acttttactt tatttaaatc aagaaatagg tgaaaaaaat
     8461 gacaaaaaca cttccaaaag actttatttt cggtggcgca acagctgctt atcaagcaga
     8521 aggtgctaca catactgatg gaaaaggacc agttgcttgg gataaatatc ttgaggataa
     8581 ctactggtac actgccgaac cagctagtga tttttacaat cgatatccag ttgacctcaa
     8641 gctagcagaa gagtatggtg tcaatggtat tcgaatttct attgcttggt cacgtatttt
     8701 cccgactggt tacggccaag taaatgctaa aggtgttgag ttttatcata atttatttgc
     8761 agagtgtcac aaacgtcatg ttgagccctt tgtaactctt catcactttg acactccaga
     8821 agctctccac tcaaatggag acttcttaaa ccgtgaaaat atcgaacatt ttgtagacta
     8881 cgctgccttc tgttttgaag aatttccaga agtaaactat tggacaacct ttaatgaaat
     8941 tggaccaatc ggtgatggtc aatatttggt tgggaaattc cctccaggta tccagtacga
     9001 ccttgccaaa gtctttcaat cacaccacaa tatgatggtg tctcatgcac gcgcggtaaa
     9061 attgtacaaa gagaaaggct ataaagggga aattggtgtt gttcacgccc tgcctactaa
     9121 atatcctcta gatcctgaaa atccagcaga tgttcgtgca gctgagttgg aagatatcat
     9181 ccacaataaa ttcatcttag acgcaactta tctaggtcgc tattcagctg aaaccatgga
     9241 aggtgtcaac catatcttat cattcaatgg tggtagtttg gatcttcgtg aagaagattt
     9301 tacagcatta gaagctgcaa aagacttgaa tgatttccta ggaatcaact actatatgag
     9361 tgactggatg gaagcctttg atggagaaac tgaaattatc cataatggta aaggtaaaaa
     9421 aggaagctct aagtatcaaa tcaaaggtgt tggtcgtcgt gtagctcctg actatgtacc
     9481 acgcacgaat tgggattgga ttatctaccc tcaaggtttg tatgaccaaa tcatgcgtgt
     9541 gaagaaagat tatcctaact acaagaagat ttacatcact gaaaatggtc tcggctataa
     9601 agatgagttc gttgataaca ctgtttacga tgatggtcgt attgattacg tgaaacaaca
     9661 cttggagatc ttgtctgatg cgattgcaga tggagctaat gtaaaaggtt acttcatttg
     9721 gtcattaatg gatgtcttct catggtcaaa cggttatgag aaacgttatg gtctcttcta
     9781 cgtagatttt gaaactcaag aacgttatcc taagaaatca gctcactggt acaagaaagt
     9841 agcggaaact cagattatag actagtagaa ttagtcatta gatatagaat tttagtgagt
     9901 caaaaagatg ttcaaagatt ttatccaatc tatttatgaa aaagtttata ttataaattt
     9961 cgaaaaatgc tctcaaatac cgtgtttgac gagtgaagaa ttgaaaagtc ttggaaaatg
    10021 gtatgtctcg actggtaaag aatggatttg tcattcagat gatgagctgg aagaatttaa
    10081 aaatctattt ttaaatttta tcaatcctga agaatgggat actatctcct ttgattcaga
    10141 ttttatgccg tttcaacaat cgtaaccaat ttctcaaaaa agttaaatct tatatttagt
    10201 actctgtaaa actcttatct aatcacgtta cttatactca atgaaaatca aagagcaact
    10261 ttaaactagg aagcgagtcg cagatttctc aatgtatagc tttgaggaat tgggcaaaaa
    10321 gtctttgata tagaaaaaag catagtatca ggtgttgaaa cacctgatac tatgcttttt
    10381 attgtgggaa gatttacttt ttttcttctg aaattgagtt gttacccagg ctctttcagt
    10441 ttattaaggc ttgatgactt taatgtgttt agatagctta aaaaggattg aatcacttag
    10501 tttagaatct gaaacaatag tatcaagatt tgatacatta taaaaagtat aaaaatcaaa
    10561 cttattgaac ttactatgat ctgcgagtaa atatttttta ttagaattat ttaaagcgat
    10621 gcgttgagcc tctccctctt cctcgctaaa agtagctaga gctccgtttt gaataccatt
    10681 acagctaacg aaagctttag aaaattggag attagagaga ttttgtaggg tcaatgtacc
    10741 aacaaaagca cctgtaatat cgcgataatt tccacctatt aaaatcaaat ctgttaattt
    10801 tcgttcgctt aaaatcagaa aaacaggtag actgttggtt acgacgcgga tattgtcaat
    10861 aggcaactca cgcgcaaaaa actctaatgt tgttcctggt ccaatgaaaa tagtttctct
    10921 ttcttctact agactgcctg caaaatgggc tatttcttgt ttttctgccg tttggagggc
    10981 ttgtttttca atatttgatc gctcattagt caaaagggag ttggttcgaa gtttttcagc
    11041 tccaccatgc acacgaatca gcaaatcttt atcagctaat tcctgtaaat agcgccttgc
    11101 agtcatatct gaaacggcta tttcgtccat aatctgttta actgttatgg ttcctttact
    11161 atttactatc tctaaaattt tggttaattt ttcttgtttg agcatattat cacctcgttt
    11221 cctactacta tcttaccata aacaaactca tcattcaaat acaaaaacaa caaaatgaaa
    11281 caaaaacaaa aatatcgaag tttgttttca aaactttcga tatttttgtt gggttattat
    11341 tttgttgttt ctagtttact ttttgatggt taagagtggt ggagaattat actcaatgaa
    11401 aatcaaagag caaactagga agctagccgc aggctgtact tgagtacggc aaggcgaagc
    11461 tgacgtggtt tgaatttgat tttcgaagag tattagtcca aaccgtagtt gtagtcatca
    11521 tcttgcatgg cttcaacttc gccaagaagg taaccatttc cgacttgaga gaagaagtca
    11581 tggttggaag ttcctgttga aataccgttc ataacgattg ggttgacatc ttcagctgaa
    11641 tctgggaaaa gtggatcttg tcccatgttc atgagagctt tattggcatt gtagcgaagg
    11701 aaggttttaa cctcttcagt ccaaccaaca ccgtcataaa gactctctgt gtagccttct
    11761 tcattttcat aaagagtata gagtaggtcg tacatccatt ctttgagttt ttcttgctct
    11821 tcttcaggca attcattgaa accaagttgg aatttgtaac caatgtaggt tccgtgaaca
    11881 gactcgtcac gaataatcaa tttaatgatt tctgcaacgt tggctagttt gttgttaccg
    11941 agatagtaga ggggagtgaa gaaaccagag tagaagagga aggtttcgag gaagacgctg
    12001 gcaactttct tttcaagtgg gctgccgttt aggtagattt cgttgacaat ctcagccttc
    12061 ttttgtaggt aaggattggt attggtccat tcgaaaattt cttcaatctc agccttagta
    12121 ttcaaggtag aaaagattga tgagtaagat ttagcgtgga cagattccat aaattggatg
    12181 ttattgaaaa cagcttcctc atgtggtgta cggatgtctg cgcgaagggc ttgaacccca
    12241 gtttcagatt gcatagtgtc aagaagggtt aaaccaccaa aaacttttcc gaccaagtct
    12301 ttctctttgt tagatagctt tctccagtca tccaagtcgt ttgataaggg aatacgtgta
    12361 tcgagccaaa attgctccgt cagtttttcc caagttgatt tgtcgatgac atcttcgatg
    12421 gcattccagt taatggcttt gtagtaagtt tccatttaaa atctctttct gtgtttagta
    12481 ttgcgaactc acaattattt ctactttacc ataattctat aggagtatcg cacaaaaagt
    12541 cggaagcccg acttttaaaa tgttacataa attatgttat gacatagtag atttgatttt
    12601 atcagtgctg cttagggaaa aataatgttt ctatgctaga aactaaatca cacagctttc
    12661 acattggttg gcgccgactt ctccaccgtc atctgtaaag gtacggacgt agtagataga
    12721 cttgattccc ttgttaaagg catagttacg aaggatggac aagtcacgtg tcgtttgttt
    12781 attttccctc ttccattcgt aaaggccttt tggaatgtca ctgcgcatga agagggtgag
    12841 tgaaagtcct tgatccacgt gttcagtcgc agcagcgtaa acatcgatga ctttacgcat
    12901 atccatatcg taggcagaag tgtagtaagg aatggtttct gtagacaagc cagcagcagg
    12961 gtagtagatt ttaccaattt tcttctcttg gcgttcttcg atacgttgcg taatcgggtg
    13021 gatagaagca gaaacgtcgt tgatatagct gatagaacca tttggcgcta cagcaaggcg
    13081 attttggtgg taaagaccat cttcttgaac cttgtcgcga agttcagccc aatcagcaac
    13141 accagggata aagacatttt tgaagagttc tttaacacgg tctgatgttg gaacaaattc
    13201 accagttaca tacttgtcaa agtaacttcc gttagcatag tctgattttt caaagttgtg
    13261 gaaggtaata ccacgttcac gtgcaatatt gtttgactct accaaggtcc agtagttcat
    13321 aagcataaag tagatgcttg taaattcaac agactcaggt gaaccatatt caatgagttg
    13381 ttgggcaagg tagctgtgca gtcccatggc accgagacca aaggtgtggg cttggctatt
    13441 tccatggtca atcgttggta cagctacgat atgtgaacta tctgtaacga aagtaagggc
    13501 acgaaccata gcacggatag aacgaccaaa atcaggtgaa gtcatcatgt taaccacgtt
    13561 ggttgaaccc aggttacatg aaacatctgt tcccatttga aggaattctt gagcatcgtt
    13621 gatcaagctt ggttcttgaa cttgaagaat ctcagaacac aagttactca tgataatctt
    13681 tccatcaaca ggatttgcac ggttagccgt atcgatgttg actacataag gatagccaga
    13741 ctcttgttgc aatttagaga tttcagtttc caaatcccgc gccttgattt ttgtcttgcg
    13801 aatatttgga tttgcgacca attcatcgta tttttcagta atgtcgatgt aattgaatgg
    13861 cacaccgtat tctttttcta cagagtaagg gctgaagagg tacatttctt catttttacg
    13921 agccaattcg tagaatttat caggtactac aacaccaagt gatagagtct tgacacgtac
    13981 tttttcatca gcgttttctt tcttagttga aaggaaagcg atgatatctg ggtgaaagac
    14041 gttgaggtag acaacaccgg caccttgacg ttgccccaat tggttggagt aagagaagct
    14101 gtcttcaaaa agcttcataa caggaacgac acctgaagca gctccttcat agcctttgat
    14161 aggtgcacca gcttcacgaa ggttgctgag ggtaattccc acaccaccac caatacgtga
    14221 aagttgaaga gctgagttga tagaacgtcc gatagagttc atatcatccg tcacttggat
    14281 taggaaacaa gataccaact ccccacgacg agcacgtcca gcattcaaga aggaaggagt
    14341 agcaggttgg tagcgttggt ggatgatttc attggcaata tcgattgcaa cagcttcatt
    14401 cccatcagcg aaataaaggg cgttgaagaa gacacggtct tccatatttt caagatagta
    14461 ttcaccgtca ttagtcttta aggcatattg attgtaaaat ttataagctg ccatgaatga
    14521 cttgaattgg aagttttggt ctttgataaa ttgagccaat tcttccaaga actctggacg
    14581 gtatttcttg ataaaggctg tttcgatgta gttgtgttca atgaggtaat tgattttgtc
    14641 tttgattgaa tcaaaaacca tagtgtttgg aactacattt tctttaaaga aagcatccaa
    14701 ggcttcctta tctttatgaa gcatgatttg tccattaaca ggacggttaa tttcgttatt
    14761 aagacggaag taagtcacgt cttcaagatg ttttaatccc ataaaatttc ccttatctaa
    14821 ttacaaaaga aaggcttcta agttagccct aaaagcagtt tcttctggat gatgtactaa
    14881 gattatgcta attgtttcag tttttctggt tggaaacctg aaaagacttc agttggtgtt
    14941 tggataacag gagctgcgct aaaaccgagc tctttaactt gatcgacgta ctcaggttgc
    15001 tcatcaagat tgatttcacg ataagagaca ttattactgt ccaagaaacg cttggtcatt
    15061 ttacattgga cacaattgtt tttagaataa acggttacca ttgtgtaact cctcttcaaa
    15121 atttaatact atcttagtat atcagaaaat aaaattttgt caat
//
LOCUS       DAVLCS010000044        14898 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLCS010000044 DAVLCS010000000
VERSION     DAVLCS010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14898
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.044"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            87..1262
                     /gene="mutY"
                     /locus_tag="VXC78_001723"
     CDS             87..1262
                     /gene="mutY"
                     /locus_tag="VXC78_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV0583750.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1318..2022
                     /locus_tag="VXC78_001724"
     CDS             1318..2022
                     /locus_tag="VXC78_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0583751.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2015..3364
                     /gene="vicK"
                     /locus_tag="VXC78_001725"
     CDS             2015..3364
                     /gene="vicK"
                     /locus_tag="VXC78_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV0583752.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3366..4175
                     /locus_tag="VXC78_001726"
     CDS             3366..4175
                     /locus_tag="VXC78_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0583753.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4266..4508
                     /locus_tag="VXC78_001727"
     CDS             4266..4508
                     /locus_tag="VXC78_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV0583754.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4510..4764
                     /locus_tag="VXC78_001728"
     CDS             4510..4764
                     /locus_tag="VXC78_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0583755.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4839..6710
                     /locus_tag="VXC78_001729"
     CDS             4839..6710
                     /locus_tag="VXC78_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEV0583756.1"
                     /translation="MTIDISEESLAKESADLLKILLKDRTTKKSIVWATHSYELLGKG
                     FAPSDRINPSKVTGNFANLIQPRSEKSKYEQKDRTKIRAEVFTPTWLVAKQNGYVESK
                     LGSLSLEEYVDLRWLEVTCGEAPYMVTRYDTVTGEEIPLSERVGFVDRKLQRISREVS
                     DEVTFYKLVKDAYHASYGYEYQGDSLLLARENLLATFEDYYLAKTGNQPTLEQKKEIA
                     TIISYNVFQMDGLKKSSPYSAKQKQSQQLSLFADELEVQEVEESKTHIKDWKKNRMIG
                     FERLSSEESEMKFDVVIGNPPYQETGEARDEPIYHYFIDEAYKIADKSILITPARFLF
                     KAGQTPKNWMEKMLEDKHLKVQFYELKSGKVFTGTDIKGGVAITYRDVDKDLGPIGVF
                     TIFETLNGIVKKIEKHPEFETFSDLVYPQGIYRFSNKLFSDYPNAEKLQGKGTKNKIV
                     SKSLTQLDFVFKNNEEKDHVALLGRIGSERVYRYINKKYLDLPETFENYNVFVPEANG
                     SGALGEVLSTPLIGEPLIGHTDTFLSIGNFKTKFEADACIKFIKTKFARVLLGVLKVT
                     QHNSRKTWYYVPLQDFTVNSDIDWTQSVADIDLQLDQKYDLSPEEIAFIENHVREMD"
     gene            6875..10129
                     /locus_tag="VXC78_001730"
     CDS             6875..10129
                     /locus_tag="VXC78_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001143847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0583757.1"
                     /translation="MPVEIKTTKEIHPKIYAYTTPTVTSNEGWIKIGYTERDVTQRIK
                     EQTHTAHIATDVLWTGDAAYTEEPDKGKTFKDHDFHHFLSFHDVERRPKTEWFYFNGT
                     PEKSKNLFDKFVQHDLSGYQPGKGQDYTLRQEQEEAVAKTLAYFQEHAGGKFLWNAKP
                     RFGKTLSTYDLARRMEAVNVLIVTNRPAIANSWYDDFETFIAGQTTYKFVSESDSLKS
                     RPILSRQEFLGILADDVRQLAFISLQDLKGSVYLGGEHDKLKWVTDLHWDLLVIDEAH
                     EGVDTFKTDQAFNKIRRNFTLHLSGTSFKALAKGDFTEEQIYNWSYADEQAAKYSWSL
                     EQEEENPYESLPQLNLFTYQMSQMIGEKLEKGAQIDGENIDYVFDLSEFFATDDKGKF
                     IHEHDVRNWLDTLSSNEKYPFSTKELRNELKHTFWLLERVASAKALKALLEEHPIYEN
                     YEIVLAAGDGRMSEEDDKVKLKSLDLVRKAIAENDKTITLSVGQLTTGVTIPEWTGVL
                     MLSNLKSPALYMQAAFRAQNPYSWSDNKGNHFRKERAYVFDFAPERTLILFDEFANNL
                     SLVTAAGRGTSATREENIRELLNFFPIIAEDRAGKMVEIDAKAVLTTPRQIKAREVLK
                     RGFMSNLLFDNISGIFQASQTVLDILNELPVEKEGKVQDSSDLLDFSDVTVDDEGNAV
                     VDHEIVVNQQMRLFGEKVYGLGESVAELVTKDEERTQKQLVNDLSKTVSSVIVEELKA
                     DYSLKTRETEQIKKQITATLENEIRKNDIERKISEAHIKQELQQQLKEANDKAQKDKI
                     QEDLEKRLEENKLIHKEKLEQTLKKEVEKMPEKFIEQVEIKRVEQLKQSAQDEIRDHL
                     RGFARTIPSFIMAYGDQTLTLDNFDAFVPEHVFYEVTGITIDQFRYLRDGGQDFAGHL
                     FDKATFDEAIQEFLRKKKELADYFKDQKEDIFDYIPPQKTNQIFTPKRVVKRMVDDLE
                     KENPGIFDDPSKTFIDLYMKSGLYIAELVKRLYNSNGLKEAFPNPEERLKHILEKQVY
                     GFAPSEIIYNISTNFIFGNLSKDISRKNFVLADTIPAAKEGSIQKLVDSYFENN"
     gene            complement(10515..11501)
                     /locus_tag="VXC78_001731"
     CDS             complement(10515..11501)
                     /locus_tag="VXC78_001731"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV0583758.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            11695..14163
                     /gene="gyrA"
                     /locus_tag="VXC78_001732"
     CDS             11695..14163
                     /gene="gyrA"
                     /locus_tag="VXC78_001732"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV0583759.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            14163..>14898
                     /gene="srtA"
                     /locus_tag="VXC78_001733"
     CDS             14163..>14898
                     /gene="srtA"
                     /locus_tag="VXC78_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV0583760.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQ"
BASE COUNT         4784 a         2522 c         3251 g         4341 t
ORIGIN      
        1 tagatagaaa agttatatac tatctattga aaatattata aatcagatac aaagacaggt
       61 gaaaccttct gtgttatact agagatatgt tagatttgaa agaatacggt atcgtcatgt
      121 ggccggagga gaaagtcatt tctttccgtg agaaacttct cgcttggtat gatgaaaaca
      181 aaagagattt gccttggagg agaagtaaaa atccttatca catctgggta tctgaaatca
      241 tgcttcagca gaccagggtg gatacagtta tcccttacta cgaaagattc ctggactggt
      301 ttccaactgt cgaaagtctg gcaactgcgc ctgaggagag tttactgaaa gcttgggagg
      361 gcttgggcta ttattctcga gttcgcaata tgcaggctgc agcccagcag attatgactg
      421 actttggtgg ccaatttcca aatacctatg aaggaatttc cagcttgaaa gggattggac
      481 cttacacagc aggagccatt tccagtattg cttttaactt gcctgagcca gctgtagatg
      541 gtaatgtcat gcgggtcttg gcgcgtctgt ttgaagtcaa ccacgatatt gggattccaa
      601 gtaatcgaaa aatttttcag gcaatgatgg agatcttgat taatccggat cgtccgggtg
      661 attttaatca agcattgatg gacttagggt ctgatattga gtctcctgta aatcccagac
      721 ctgaagaaag cccagtcaag gactttagtg cggcatatca gaatggaacc atggaccgtt
      781 atccaattaa atctcctaag aaaaagccgg ttcctattta tcttaaagcc ttagttgtga
      841 aaaattctca aggacaattt ttacttgaaa aaaatgaaag cgaaaagctc ttggcaggtt
      901 tttggcattt cccctttata gaagttgata acttttcgca agaagagcag tttgacctct
      961 ttcatcaggt tgcggaagaa agtgtgaact ttggtcccag tccagaagag agtttccagc
     1021 aggactatga cctagatgtt gattggcttg atgtttgttt tgatacagtc cagcatgttt
     1081 ttagtcatcg aaaatggcat gtacagattg tagcaggtca ggtgagtgac ttccatgatt
     1141 tttcagatag ggaagttcgt tggctttcac cagaagaatt caagaattac ccacttgcca
     1201 aaccccaaca aaaaatctgg caggcttatg cacaagccaa cttagacagt agccaagact
     1261 agctattgtg tcttctgact atttttttgg tataatagta gagaaaaagg tgaacatatg
     1321 aaaaaaatac taattgtaga tgatgagaaa ccaatctcgg atattatcaa gtttaatatg
     1381 accaaggaag gttacgaagt tgtaactgct tttaatggtc gtgaagcgct agagcaattt
     1441 gaagcagagc aaccagatat tattattctg gatttgatgc ttccagaaat tgatggttta
     1501 gaagttgcta agaccattcg taagacaagc agtgtgccca ttcttatgct ttcagccaaa
     1561 gatagtgaat ttgataaggt tatcggtttg gaacttgggg cagatgacta tgtaacgaaa
     1621 cccttctcca atcgtgagtt gcaggcgcgt gttaaagctc ttctgcgtcg ttctcaacct
     1681 atgccagtag atggtcagga agcagatagt aaacctcaac ctatccaaat tggggattta
     1741 gaaattgttc cagacgccta cgtggctaaa aaatatggcg aagaactaga cttaacccat
     1801 cgtgaatttg agcttttgta tcatttagca tcgcatacag gtcaagtcat cacgcgcgaa
     1861 cacttgcttg agactgtctg gggttatgac tattttggtg atgtccgtac agttgatgtg
     1921 actgtacgac gtctgcgtga gaagattgaa gatacgccca gccgaccaga gtatatcttg
     1981 acgcgccgtg gtgtagggta ttacatgaga aataatgctt gatttactga aacaaaccat
     2041 ttttaccaga gattttatct ttatcctgat tttgttaggt ttcatccttg ttgtgaccct
     2101 cttattactg gaaaatagac gtgataatat tcagttgaag caaatcaatc aaaaggttaa
     2161 agatttgatt gcaggagatt attccaaggt tcttgatatg caaggtgggt ctgaaatcac
     2221 caatattacc aataatttga atgacttgtc ggaggttatt cgtctcactc aggaaaatct
     2281 agaacaagag agtaagaggc taaatagtat tctgttttat atgacagatg gggttcttgc
     2341 gaccaaccgt cggggtcaga ttatcatgat taacgataca gccaagaagc aactggggtt
     2401 ggttaaggaa gatgttctga atagaagcat tttggaattg ctcaagatag aagaaaacta
     2461 tgaattgcgt gatttgatta cccaaagtcc agaattgttg ctagattccc aagatatcaa
     2521 tggtgaatat ttgaaccttc gagttcgctt tgccttgata cgtcgagagt ctggctttat
     2581 ttcaggtttg gtggctgttt tgcatgatac gacggagcag gagaaggaag aacgcgaacg
     2641 aagactcttt gtttccaatg ttagccatga gttacggact cctctgacta gcgtaaaatc
     2701 ctatcttgaa gccttggatg agggggcttt gtgtgaaact gtagcaccag actttatcaa
     2761 ggtttctctt gatgagacca accgtatgat gcgcatggtg acggatctcc tccatctttc
     2821 acgtattgat aatgctacca gtcacctaga tgtggaactg attaacttca ctgcttttat
     2881 tacctttatc ctcaatcgtt ttgacaagat gaaaggacag gaaaaggaga aaaaatatga
     2941 gttggtgaga gattatccca tcaattctat ctggatggaa attgatacag ataagatgac
     3001 gcaggttgtc gacaatattt taaataatgc tattaagtat tcgccagatg ggggtaaaat
     3061 cactgtcaga atgaagacaa ctgaagacca gatgatttta tccatttctg accacggttt
     3121 ggggattcct aagcaggatt taccacgtat ctttgaccgt ttctatcgtg tggatcgtgc
     3181 tagaagtcgt gcacaaggtg gtacaggtct aggactgtct atcgctaaag aaattattaa
     3241 acaacataag ggctttattt gggccaagag tgaatacggc aagggttcaa cctttaccat
     3301 tgtgctccct tatgataagg atgcagtgaa agaagaagta tgggaggatg aagtagaaga
     3361 ctagaatgag tgaaataggc tttaaataca gtattttagc gtcgggttcc agtggaaatt
     3421 ctttttatct ggaaacctca aaaaagaagc ttttagtgga tgcaggcttg tctggcaaga
     3481 aaattaccag tctgctagct gaaattaacc gcaagccaga agacctggat gccatcttga
     3541 ttacccatga gcattcagat catatccatg gagtaggcgt tttggctcgc aagtatggta
     3601 tggatcttta tgccaatgaa aagacctggc aagctatgga aaatagtaaa tatcttggca
     3661 aggtggattc ttcgcaaaag catatttttg aaatgggtaa aaccaaaact tttggagata
     3721 tcgacatcga gagttttggt gtaagccatg atgcagtcgc accgcagttc tatcgcttta
     3781 tgaaggatga caagagtttt gtccttttga cagatacagg ttatgtcagt gaccgtatgg
     3841 cgggcattgt cgaaaatgcg gatggctatc ttatcgaggc caaccatgat gtagagattt
     3901 tgcgatcagg ttcttacgct tggcgactca aacaacgaat cctatctgac cttggtcacc
     3961 tttctaacga ggacggtgct gaagctatga ttcggacgct aggaaatcgc actaagaaga
     4021 tttaccttgg gcatttatct aaggaaaaca atatcaagga actggctcat atgaccatgg
     4081 tcaatcagct ggctcaagct gatctgggag tcggagtaga ctttaaggtt tatgatacct
     4141 caccagatac cgcaacacca ttgacagaga tatagaaaga acgctgagaa ggtgttcttt
     4201 ttatattgac tgaacaccta aaaagtaata caatggtgtt accattaaaa aagggagcac
     4261 aaaagatgac tactattaca ttaaaagttt ctgaagctga taaaacattt atgaaagcaa
     4321 tggctaagtt tgaaggagtt tccctttcgg aacttattcg caccaaaact cttgaagccc
     4381 tagaagatga atacgatgct cgtgtggcag atttagccta tcaagagtat ttagaagact
     4441 tggaaaaagg agttgaaccc attacttggg aagaaatgat gcatgattta ggcttgaagg
     4501 atgaataatt tgtataaatt agttccaaca agacgtttta tcaagcaatt gaaaaaattg
     4561 gaccgttata cgcagaagct aattacaaac tatttacaaa ccaatgtttt ggaagaccca
     4621 agacgacacg gaaaggcttt ggttggtaat cgcgttggtc aatggcgcta tagaattggt
     4681 aattatcgag ttatcgtaca aattgtagat gatgaattag tcgttgctac tctagaagtt
     4741 ggtcatcgga gagatattta ttgaattact tttttcaagt aaattttcat tctttaaaat
     4801 atgatataat agggcttaca atataagaga ggttgctgat gacaatagat attagtgaag
     4861 aaagtttggc taaagaatcg gctgacttat taaaaattct tttaaaagat cgaacgacaa
     4921 agaaatcaat tgtttgggct acgcattctt atgaattgtt aggaaaggga tttgctccaa
     4981 gtgatcgcat caatccaagt aaggttactg gaaactttgc caacttgatt cagcccagat
     5041 ctgaaaaatc caaatatgaa caaaaagatc ggacaaaaat aagggcagaa gtgtttacac
     5101 caacgtggtt ggtcgcaaag caaaatggat atgtagaatc gaaattaggc tcgttaagtc
     5161 ttgaggagta tgtggactta cgatggttag aggtaacttg tggtgaagca ccttatatgg
     5221 taacgagata tgataccgta actggtgagg aaattccatt atctgagcga gttggttttg
     5281 ttgatagaaa actgcaacgg attagtcgtg aggtttcaga tgaagtcaca ttttataaac
     5341 ttgtaaaaga tgcttatcat gcttcgtatg gttatgagta tcaaggagat tctctccttt
     5401 tggcgcgtga gaatcttttg gcaacttttg aggactatta tctagctaag actggaaatc
     5461 aaccaacatt agagcaaaag aaagaaattg cgactattat ctcttacaat gtctttcaga
     5521 tggatggatt gaaaaaaagt agtccttatt cagctaaaca aaagcaatct caacaattga
     5581 gtttgtttgc ggatgagcta gaagtccaag aagtagaaga atctaaaacc catatcaaag
     5641 actggaaaaa gaatagaatg ataggttttg agcgcctatc tagcgaggaa agtgaaatga
     5701 aatttgatgt cgtgatagga aatcctccgt atcaggaaac aggagaagcc agagatgagc
     5761 cgatatatca ctattttatt gatgaagctt ataaaatcgc agataaatct atactaatca
     5821 ccccagcaag gtttttattt aaagctggtc aaactcctaa aaattggatg gaaaagatgc
     5881 ttgaagacaa gcatttaaaa gttcaattct atgaacttaa aagcggtaaa gtatttacag
     5941 gaacggatat taagggtgga gtagcaataa cttatcgtga tgttgataaa gatttgggac
     6001 caatcggagt atttactatt tttgaaactt tgaatggtat tgtaaaaaaa atcgaaaaac
     6061 atccagaatt tgaaactttt tctgatttag tttatcctca aggtatttat agattttcaa
     6121 ataaactttt ttctgattat ccaaatgctg aaaagctgca aggaaaaggg acaaaaaata
     6181 aaattgtttc gaaatcacta actcagttag attttgtttt caaaaacaac gaagaaaaag
     6241 accatgttgc tctacttgga agaattggct ccgaacgtgt ttatcgatat attaataaaa
     6301 aatatttaga tttaccggaa acattcgaaa attataatgt ttttgtacca gaagctaatg
     6361 gaagtggtgc cttaggtgaa gtcttatcaa cacccctaat cggggaaccc ctaatcgggc
     6421 atacagatac ttttttatct attggtaatt ttaaaacaaa atttgaagcc gatgcttgta
     6481 ttaaatttat taaaactaaa ttcgctagag tattattagg tgttttgaaa gttactcagc
     6541 ataattcacg caaaacttgg tattacgtcc ccctccaaga ctttacggtc aattcggaca
     6601 ttgattggac acaatcagtg gctgatattg acctccagct tgatcaaaaa tatgaccttt
     6661 cccctgaaga aattgccttt attgagaatc atgtaaggga gatggattag aaaagtattt
     6721 ttatttgaca aatagtgctc aatgatctaa aatgactata taggattagg tcaggaagca
     6781 tacgatgccc tgaccctttt tgtacttatg agatgagaaa gtcatttgtt agataaattg
     6841 acttcgttag caaacgttca aaaaaggaaa acttatgcca gtagaaatta aaaccactaa
     6901 agagattcat cctaaaatct atgcctatac cacaccgaca gtaaccagta atgaaggctg
     6961 gattaagatt gggtatacag aacgtgatgt cacacaacgt atcaaggagc aaacgcatac
     7021 agctcatata gctacagatg tcttatggac tggtgatgca gcttatacag aagagcctga
     7081 taaggggaaa actttcaagg accatgattt ccaccatttc ctttctttcc atgatgtaga
     7141 acgtcgtccc aagacggaat ggttctattt taatggaact cctgaaaaat caaaaaatct
     7201 ttttgataag tttgttcagc atgatttgtc tggttatcag cctggaaaag gacaggacta
     7261 tactctgcga caagagcaag aagaagcagt tgctaagaca ttagcttatt tccaagaaca
     7321 tgctggaggc aagtttctct ggaatgccaa gccacgcttt ggtaaaacct tgtctaccta
     7381 tgacctagct cgacggatgg aagctgtcaa tgtcctaatt gtaacaaacc gccctgccat
     7441 tgctaactca tggtatgatg attttgaaac attcatagca ggtcaaacga cttacaagtt
     7501 tgtttctgaa tcagatagcc ttaagagtcg tccaatcttg tcacgacaag aatttcttgg
     7561 tattttagct gacgatgtaa gacaacttgc ttttatcagt ctccaagact tgaaaggatc
     7621 tgtttattta ggtggagagc acgataaact caaatgggta actgatctgc attgggactt
     7681 gttggttatt gacgaggctc atgaaggagt tgataccttc aagactgacc aagcctttaa
     7741 taagattcga cggaatttta ctctgcattt gtcaggtaca tcatttaaag cattggctaa
     7801 aggagatttt acagaggaac aaatctacaa ctggtcttat gctgatgagc aggctgctaa
     7861 gtattcgtgg tctcttgagc aagaagagga aaatccttat gaaagcttgc ctcagttgaa
     7921 tctctttacc tatcaaatgt ctcagatgat tggcgaaaag ttagaaaaag gcgctcagat
     7981 cgatggtgaa aatattgact atgtttttga cttaagtgaa tttttcgcta cagatgataa
     8041 agggaaattt attcatgagc atgatgtcag aaattggtta gatactctat caagcaatga
     8101 aaaatatcca ttttcaacca aagaactccg taatgaactc aagcatactt tttggctttt
     8161 agaacgtgtc gcttcggcca aagcattaaa agccctacta gaagaacacc caatctatga
     8221 aaactatgag atcgttctag ctgctggtga cggacgtatg tccgaagaag acgataaagt
     8281 caaactcaaa tccttggact tggttagaaa agcgatagca gagaatgaca aaaccattac
     8341 cctatccgtt ggtcagctga cgacaggtgt cactatccct gaatggacag gtgtattgat
     8401 gttatcaaat ttgaaatcac cagctcttta tatgcaggcc gccttccgtg ctcaaaatcc
     8461 ttactcatgg agcgataaca aaggaaatca ctttcgcaaa gaaagagcct atgtatttga
     8521 ctttgcgccg gaaagaacct tgattctctt tgatgagttt gccaacaact tatcgcttgt
     8581 aactgcagct ggtagaggaa cttcagctac acgcgaagaa aatattagag aattattaaa
     8641 cttctttcca attattgccg aagaccgtgc tggtaagatg gttgaaattg atgcaaaggc
     8701 agttctaacc actcctcgcc agataaaagc tagagaagtt cttaaacgag gttttatgtc
     8761 caatctctta tttgataata ttagtggtat tttccaagca agtcaaacag ttttagatat
     8821 tttaaatgag ctgccagttg aaaaggaagg gaaggtacaa gatagttctg atttattaga
     8881 tttttcagat gttacagtcg atgatgaggg aaatgcagta gtagaccatg aaattgtagt
     8941 taatcagcaa atgcgacttt ttggtgaaaa agtttatgga cttggtgaat ctgttgctga
     9001 gttagtcaca aaagatgagg aacgaactca aaaacagctg gtcaatgact tgagtaagac
     9061 cgtttcttca gtgattgtag aggaattgaa agcagattat tctctaaaaa caagggaaac
     9121 tgagcaaatt aagaaacaaa ttacagcaac acttgagaat gaaattcgaa aaaatgatat
     9181 cgaaagaaaa atttctgaag ctcatatcaa gcaagagttg caacagcagc tcaaagaagc
     9241 aaatgataaa gcgcaaaaag ataagattca agaagattta gaaaaacgtt tagaagaaaa
     9301 taaactcatt cataaagaaa aactagaaca aacactcaaa aaagaagtgg aaaaaatgcc
     9361 tgagaaattt atcgaacagg ttgagataaa acgtgtggaa cagttgaaac aatcagctca
     9421 agatgaaatt cgtgaccatt tacgagggtt tgcaagaaca attccaagtt ttattatggc
     9481 ttacggtgat caaactctaa cacttgataa ttttgatgcc tttgttcctg aacatgtttt
     9541 ttatgaagta acagggatta cgattgatca gtttagatat ttgcgagatg gtgggcagga
     9601 ttttgcaggg catctctttg ataaagcaac atttgacgaa gctattcaag aatttcttcg
     9661 caagaaaaag gagttggcgg attattttaa agatcaaaaa gaagacattt ttgactatat
     9721 tccaccgcag aagaccaacc aaattttcac tcctaaacga gtggtgaaaa ggatggtaga
     9781 tgatttggaa aaggaaaatc cagggatttt tgatgatcca tctaagactt ttattgattt
     9841 atatatgaag tcaggcctct atattgcaga acttgtgaag cggttatata atagcaatgg
     9901 cttgaaagag gcctttccaa atcctgaaga acgcttaaaa catattttgg aaaagcaagt
     9961 ttatggattt gctccgtctg agattatcta taacatttcc actaatttta tatttggtaa
    10021 tctttctaaa gatatcagta ggaagaattt tgttttagca gataccattc cagcggctaa
    10081 agaagggagc attcaaaagt tggttgattc ctattttgaa aataattaaa aagaaggccg
    10141 agtcaaaatt ctttgaaatc agaaaaaacg cataatattg agtgcttttg tactgccccc
    10201 aaaaagttag acagaaaaaa tctaactttt ggggggcagt tcagacaatc cttggtatta
    10261 tgcgttttat tgtgggaaga tgtataatgg attgaaataa gatatgaaca aatcgattag
    10321 gaaaggaaaa ttgatttata gaaatgtttt agtagtcgat gcgtactgtt atagattcaa
    10381 cgaactataa aatctgaaga aagcaatttt aaccagatct tagaagcagt tgtgtactac
    10441 tctaacttca atagactata tcatatagat aaaaaacaac tccctgatga ttcaaggagt
    10501 tgtctatagt taaattagtt tttagaagct tcttggaatt ctggattttt ccatgcttcg
    10561 tcaatgatag cttgcaattc tttagcagat gcttgcattt tttgagtttc tgcatcgttc
    10621 aatggaatgt ttactggacg aacgatacca tgtgcaccaa caacagctgg ttgaccgata
    10681 aagacattct caactccgta ttgaccttct tggaatactg aaagtggaag tactgcgttt
    10741 tcatcgtcaa ggattgcttt agtgatacga gcaagggcta ctgcgatacc gtagtatgtt
    10801 gcaccttttt tgttgatgat tgtgtaggct gcatcacgaa caccttcgaa caattcaatc
    10861 aattcagctt cttgaacatt ttgagtgtct ttaaggaatt cttcaaggtt tacaccagcg
    10921 atgttagcgt gtgaccaaac agcgaactca gagtcaccgt gttcacccat gatgtaggcg
    10981 tgcactgaac gagcatccac atccaatttt tcagcaagtg cttgacggaa acgagctgag
    11041 tcaagtgaag tacctgaacc gataacgcgt tctttaggga aaccagagaa tttccaagtt
    11101 gagtaagtca aaacgtcaac tgggttagca gcaacaagga agataccttt gaaaccagat
    11161 tcaacaactt gagttacgat tgatttgttg atagcaaggt ttttacctac aaggtcaaga
    11221 cgagtttcac ctggtttttg aggtgcacct gcagtgatca caacaaggtc agcgtctgca
    11281 cagtcagagt attgagctgc atagattttt ttaggtgaag tgaaggcaag ggcgtgacta
    11341 aggtcaagcg catcaccaac agctttttca tgcaattgtg gaatttcgat aattccaagc
    11401 tcttgtgcaa ttccttggtt aacaagtgca aaagcgtaag atgaacctac agcaccatca
    11461 ccgacaagga taactttttt gtgttgttta gttgaagtca ttgttttaaa catctcctta
    11521 attttattag gggattttcc ctagacaact tcattctatc acttttaaaa aactttgtca
    11581 cgaatatgcc ttatagttct cgatgtaaac gttttagtgg tttagaggct gaaatagatg
    11641 ggaatttatg gtataatgtt gttacttact aattgtgaaa tgaggcattt attaatgcag
    11701 gataaaaatt tagtgaatgt caatctgaca aaggagatga aggcaagttt tatcgactac
    11761 gccatgagtg ttatcgtagc gcgagctctt cctgatgttc gagatggctt aaaacctgtt
    11821 caccgtcgca ttctctacgg aatgaatgaa ttgggtgtga ccccagacaa accccataaa
    11881 aaatctgctc gtattacagg ggatgtcatg ggtaaatatc acccacacgg ggattcctct
    11941 atttatgaag ccatggtccg tatggctcaa tggtggagct accgttacat gcttgtagat
    12001 ggtcatggga attttggttc catggatgga gatagtgctg ccgctcaacg ttataccgag
    12061 gcacgtatga gcaagattgc tctggaaatg cttcgtgata tcaacaaaaa tacagttgat
    12121 ttcgttgata actatgatgc caatgaacgg gaacccttgg tcttgccagc gcgttttcca
    12181 aaccttttgg ttaatggagc aactggtatc gcggttggga tggcaaccaa tattccacct
    12241 cataatctgg gtgaaaccat tgatgcagtg aagttggtca tggataatcc tgaagtgact
    12301 accaaggact tgatggaagt cttgcctgga ccagattttc caactggtgc tcttgtcatg
    12361 gggaaatcag gtatccataa ggcttatgaa acaggtaaag gttcgattgt cctacgttct
    12421 cgtacagaga ttgaaacgac taagactggt cgtgagcgta tcgttgtaac agaatttcct
    12481 tacatggtca ataaaaccaa ggtgcatgag catattgttc gcttggttca ggaaaaacgc
    12541 attgagggta tcacagcagt acgtgatgag tcaaaccgtg aaggtgttcg atttgttatt
    12601 gaagtcaagc gcgacgcctc agccaatgtt attctcaata acctcttcaa aatgacccaa
    12661 atgcaaacca attttggttt caatatgctc gctatccaaa atggtatacc gaaaattttg
    12721 tctcttcgtc agattttgga tgcttatatc gagcaccaaa aagaagtggt tgttcgtcgt
    12781 acacgttttg ataaggaaaa agcggaagcg cgcgctcata tcttagaagg tctcttgatt
    12841 gcgctagacc atatcgacga agtgattcgt atcatccgtg ctagtgaaac ggatgcggaa
    12901 gctcaagctg agttgatgag caagtttaag ctttctgaac gtcaaagtca agctatcctt
    12961 gatatgcgtc ttcgtcgttt gacaggtttg gaacgcgata agattcaatc tgagtatgat
    13021 gacctcttgg ctctgattgc ggatttagca gatattcttg ctaagcctga acgtgtttct
    13081 caaattatca aagacgaatt ggatgaagtt aaacgtaaat tttctgataa acgccgtaca
    13141 gagttgatgg ttggacagat cttgagtctc gaggatgagg acttgattga agaatcggat
    13201 gtcttgatta ccctttctaa cagaggctac attaagcgtt tggatcagga cgagttcact
    13261 gctcaaaaac gtgggggtcg tggtgtccaa ggaacgggag tgaaagatga tgactttgtt
    13321 cgtgagttag tgtcaactag cacccatgat catctgctct tcttcacaaa caagggacgt
    13381 gtctatcgtc ttaaaggtta tgaaattcct gagtatggtc ggactgccaa agggctacca
    13441 gtagtcaatc tcttgaaatt ggatgaagat gaaagtattc agacggttat caatgttgag
    13501 tctgatcgca gtgatgatgc ttatctcttc tttacaaccc gtcacggtat tgtgaagaga
    13561 actagtgtta aggagtttgc caatattcgt caaaatggtc tcaaagcgct gaatttaaag
    13621 gatgaagatg agttaatcaa tgtcttgttg acagaaggag atatggatat tatcattggt
    13681 accaagtttg gttatgcagt tcgctttaat caatcagccg ttcgtggtat gagccgtatc
    13741 gccactggtg tgaaaggtgt taaccttcgt gaaggagaca cagttgttgg tgccagcttg
    13801 attactgatc aagatgaggt tcttattatc acagaaaaag gatatggtaa gcgtacagtc
    13861 gctactgaat acccaacaaa aggtcgtggt ggtaagggaa tgcagacagc taaaattacc
    13921 gaaaaaaatg gcttgctggc cggtcttatg actgttcaag gtgatgagga tttgatgatt
    13981 atcactgata caggtgtcat gattcgaacc aatcttgcca atatttcaca aacaggacgt
    14041 gcaactatgg gagttaaagt aatgcgcctg gatcaagatg ctcagatagt gactttcaca
    14101 acggttgcgg tggcagaaaa agaagaagtt gggacagaaa acgaaacaga aggtgaagca
    14161 taatgtctca aaaaaataat aaaaagaaaa acaagcgaaa aaatctgctg acaaatatcc
    14221 tagcaggatt tctgatatta ctgtcactgg ctttgatttt taatactcaa attcgaaata
    14281 ttttcatagt ctggaatacc aataagtatc aagttagcca ggtatcaaaa gaaaaattag
    14341 aagaaaatca ggatacagaa ggcaattttg actttgattc tgtcaaagct atctcttcgg
    14401 aagctgttct aacttctcaa tgggatgctc aaaaattacc agttattggg ggaattgcaa
    14461 ttcctgaatt ggaaatgaat ttgccgattt ttaaaggact tgataatgtt aatctcttct
    14521 acggagctgg tacaatgaaa cgcgagcaag taatgggaga aggaaattat agtctagcta
    14581 gtcaccatat ctttggtgtt gataatgcta ataaaatgtt attttctcct ttagataatg
    14641 ctaaaaatgg catgaagatt tatctaaccg ataaaaataa agtttatact tatgaaatac
    14701 gtgaagtcaa acgtgtgaca ccggatcgtg ttgatgaagt tgatgataga gatggggtca
    14761 atgaaatcac attagtaacc tgtgaagacc ttgctgctac agaacgtatt attgtcaaag
    14821 gtgatttgaa agaaacaaaa gattattcac aaacatctga tgaaatccta acagctttca
    14881 atcaaccata taaacaat
//
LOCUS       DAVLCS010000045        14454 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLCS010000045 DAVLCS010000000
VERSION     DAVLCS010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14454
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.045"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(123..1973)
                     /locus_tag="VXC78_001734"
     CDS             complement(123..1973)
                     /locus_tag="VXC78_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0583761.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(2015..3172)
                     /locus_tag="VXC78_001735"
     CDS             complement(2015..3172)
                     /locus_tag="VXC78_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0583762.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            3230..4396
                     /locus_tag="VXC78_001736"
     CDS             3230..4396
                     /locus_tag="VXC78_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV0583763.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            4535..4861
                     /locus_tag="VXC78_001737"
     CDS             4535..4861
                     /locus_tag="VXC78_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0583764.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            4848..5441
                     /locus_tag="VXC78_001738"
     CDS             4848..5441
                     /locus_tag="VXC78_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV0583765.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            5434..6345
                     /locus_tag="VXC78_001739"
     CDS             5434..6345
                     /locus_tag="VXC78_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV0583766.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6407..7471
                     /locus_tag="VXC78_001740"
     CDS             6407..7471
                     /locus_tag="VXC78_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583767.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAAESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(7542..8402)
                     /locus_tag="VXC78_001741"
     CDS             complement(7542..8402)
                     /locus_tag="VXC78_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV0583768.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWRIIKLFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAHLTDNAVRFTICQGIFNPIFFSHEDLKSFLEEDGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGQVHGVYHLAQGVKTVLPREPFVPAAYMEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILG
                     QDFKTLAQEK"
     gene            complement(8524..9510)
                     /locus_tag="VXC78_001742"
     CDS             complement(8524..9510)
                     /locus_tag="VXC78_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV0583769.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(9782..11257)
                     /locus_tag="VXC78_001743"
     CDS             complement(9782..11257)
                     /locus_tag="VXC78_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV0583770.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(11515..12438)
                     /locus_tag="VXC78_001744"
     CDS             complement(11515..12438)
                     /locus_tag="VXC78_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0583771.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(12452..13381)
                     /locus_tag="VXC78_001745"
     CDS             complement(12452..13381)
                     /locus_tag="VXC78_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0583772.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(13700..13921)
                     /locus_tag="VXC78_001746"
     CDS             complement(13700..13921)
                     /locus_tag="VXC78_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583773.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            complement(13875..14135)
                     /locus_tag="VXC78_001747"
     CDS             complement(13875..14135)
                     /locus_tag="VXC78_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583774.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            14215..14352
                     /locus_tag="VXC78_001748"
                     /pseudo
     CDS             14215..14352
                     /locus_tag="VXC78_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         4334 a         3088 c         2666 g         4366 t
ORIGIN      
        1 taaccatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtataagt
       61 ctctacataa taaaacgcat attaccaagg ttgtgtaact tgatactatg cgtttttctt
      121 ttttattcaa tgtgggttgt ttgattagca aaggcgataa tagcttgctt caactcatct
      181 ccactgagag tgcggaactc tccaatcttt tgattgatgg attctaaagg catgacatta
      241 accttaccaa cgaaaatctt atccataact tgattatcaa cgagttcggt tgataccaag
      301 agttcttcgt agagtttttc acctgggcgg attccaactt caacgattgg aatttcactt
      361 tcagtgtggc cacttagaag caccatcttc ttggccaagt cataaatctt gactggtttg
      421 cccatatcaa ggataaagac ttccccatct ttggcataag caccagcatg gataaccaga
      481 cggctagctt ctggaatggt cataaaataa cgggtcatgc ggaagtctgt caccgttaca
      541 ggcccacctt cagcaatctg acgttcaaag actggaatga cactaccacg gctaccaaga
      601 acattcccaa aacgaactgc acagtaggtt gattggctac gttggttaaa gccagtgaca
      661 atcaactccg ccacgcgctt ggttgctccc ataacatttg gtggattgac tgccttatct
      721 gtcgaaatca taaccatctt agacacttta gcttcatcaa cagccttagc aacattgtaa
      781 gttccacgga tattgttttt gaaggcttct tttggattgc gctccatcat aggaacatgc
      841 ttgtgggctg ccgcatgata aacaatagca ggtttgtact gctcaaagac ttgcaacaaa
      901 cgatcatagt cttgaatgtc cgcaatcaca ggtacataat caatcccttg gaacttacga
      961 atcaattcat gataaacaag gtagattgag ttttccccat gaccgagcaa gacaatgcgt
     1021 tcaggattga agcgactaac ttgacgacag atttcagaac cgattgaacc tccagctcct
     1081 gtgactaaga tggtcttacc tgtcagttct gcacccagac gcgattcgtc aagacggatt
     1141 tcctgacgac ccaaaaggtc cgtaatatca attttttgga agccagtacc tgcttggtga
     1201 aggccctgaa caacagtttc aaccttaggc atcttgtaac atttgacacc cagcttatta
     1261 cacatctgca agatacgctc atattctgac ggatccagcg acggaatcgc aacgatgaca
     1321 cgctcgattt gatggcgttt ggctaattca ggcagattgt cataagagcc caaaacagga
     1381 ataccaccaa gtttttgacc ctttttctta gaatccttat ccaaaatacc gaccagttct
     1441 aattcactgg ttggatgttg gtaactatcc ataaaaagag ccccaccatc accggcacca
     1501 atcaagaagg tccgacggtg ttctccatca ccactacctt ttttgcgtct ggagtagatt
     1561 aactgccaag taatccgtgg caataaaatc aagaaggtac tcaacaagat aaagagaatg
     1621 atgaaacgga tggagaagag tggcaagaag gcataacaga tactatatga caagacactg
     1681 ctagcagtca caccaaaaaa gattttcatg aaatccgtaa tcttgctgta acgactaatg
     1741 ctcgcgttca acccccaaaa accaatcatc aattgataga acaggaaggc caaactcgta
     1801 tagataatgt agtcaacagg tgctggatta atcagcccat aaaataaaat ataagataca
     1861 atgatggaaa ccaccatact gaaaatatca aatattcccc agaaaacctg cttttgttgt
     1921 ttatttaaaa tttccaccag atcaatcaca taatctgtta gttttttatt catagaaatc
     1981 tactcctcct taaaagagtt ttactatatt gttattatag catattttga tttatttggc
     2041 ttattttatc caaataaatt attgttccct tgtactcctt cttccattta aatcctctaa
     2101 ttaaacctac aatcgtccca aagccataag caaagtgaat ggaaaataaa agaaagggca
     2161 tcacaattag aaatccattt ttatgtttta ataaagtcag caaagtgagt agtgacaaaa
     2221 gtagaaaata ggcacctaat agtaaagtta tgaatacgaa tgtgatcggt aacaatgcta
     2281 gactaaacac aagactcaaa acaaataaac aaggaacata gtgaaataat gataaacact
     2341 taaactgaac atgacttgtc aagccaatcc acaaaccatt tgaatacttt tgatgcagca
     2401 ttttcttgaa tgttggtcga atatactgat aagatagaat acttgggcta tagcggattt
     2461 tataaccatg ttctcgaatt ctataatgaa tatcattatc ttcagttcgg ccaagttgct
     2521 catttactaa accaaccttc tggaaaacct ctcgtttata cattccatga aaaatagaag
     2581 aaacatatct atcctcggaa ctatttcgat aattggcaat gctactgcca aacatatttt
     2641 cctcaacaag atgcaaggtc tctgcccatt ttccttttcc ttcgacaatc gtcggtctag
     2701 gccccccaca gacaaattca ccttgttgaa taatagccac attgttcatt acaaaagtct
     2761 cagtaacttt tgaatgagca tcaattttta aaataaggtc ccctacagaa tgtttaactc
     2821 ccaggttaaa accactagct tgatttttct taggattgtt atacaatcta attgagttaa
     2881 actctgtatc ttcctttata aattgctgaa tgatagctgt ggtcccatct gtggacatag
     2941 catttataaa tagaatttca atattctctt taggataagt ttgatttttt aagtcttcaa
     3001 ttagaccagg cagatatttt tcttcattgt atgcactgat tacaatggat acgagaagac
     3061 tttcaacatt ttgagtcact actactctcc tgaatttttc cttccaccat tctatcataa
     3121 ttttcaagac tttcccattt ttatcttgaa agccagaaac cttacttgac attatagtga
     3181 aaaagcctta aaataagctg ttattaaaat cagctagaag aggtattata tgaaaaagca
     3241 atcactcttt tttgttccag gtattatcct gattggtgtt tccttgcgaa ctccttttac
     3301 tgttttaccc attattttgg gaaatatttc gcaaggtctg gaggtagaag ttagttcgct
     3361 tggtgtcttg accagcctgc ctctccttat gtttaccctc ttttcaccat tttctaccca
     3421 actggctcag aaaatcggct tggagcatct cttcacctac agcctcttct tcttgaccat
     3481 cggctcactt attcgactaa tcaatctgcc cctactctat ctaggaacct tgatggttgg
     3541 ggcaagtgtc gcagtcatca atgtcctgct tcctagtctt atccaagcca atcaaccaaa
     3601 gaaaattggt tttctgacca ccttatatgt aacgtctatg gggattgcaa cggctctggc
     3661 ttcctatcta gctgtgccca ttacacaagc cagttcttgg aaaggactta tccttctcct
     3721 cacgttactc tgtctagcaa cttttttggt ctggctccca aatcaccgct ataatcatag
     3781 actagctcca caaaccaaac aaaaaagtca aataaaggtc atgcgtaata aacaggtttg
     3841 ggcaattatt atcttttcag gttttcaatc cttgatcttt tacaccgtca tgacctggtt
     3901 acctaccatg tctatccatg caggtctatc cagtcacgaa gctggcttgc tgacttctat
     3961 cttatctctg attagcattc ctttttcaat gaccatccca agcctgacaa ccagtttatc
     4021 tactcgcaac cgtcagctca tgctcactct ggtttcacta gctggtgtgg tcggcatttc
     4081 catgctcttt ttcccaatca ataatttcat ttactggctt gccatccatc tcctcatcgg
     4141 aaccgcaacc agtgccctct tcccttatct catggtcaac ttttcactca agacaagcgc
     4201 ccctgaaaag acagcccaat tgtccggcct atctcaaaca ggaggctata tcctagcagc
     4261 ctttgggcca accctctttg gttacagttt tgacctgttc cactcttggg taccatctgt
     4321 agctgccctc ttgctcatcg atatcctgat gactgtggcc ctctttacag tggacagagc
     4381 ggataagatc ctttaaactt ctagttttag ctagaagttt tttatatata aaaattttac
     4441 acatttctct tgacagggct ttcttttaga tgtacaatgt atgtgtagaa aaattatata
     4501 taaaaatctt acacattaga aaaggaggtt tcccatgtac tttccaacat cctctgcctt
     4561 gattgaattt ctcatcttgg ctgtactgga gcagggtgat tcttatggtt atgagattag
     4621 ccaaaccatt aagctgatcg ctaatatcaa agaatccaca ctctatccca ttctcaaaaa
     4681 attggaaggc aatagctttc tgacaaccta ttctagagag ttccaaggtc gcatgcgcaa
     4741 atactactcc ttgacaaacg gtggtataga gcagctcttg accctaaaag atgaatgggc
     4801 actctataca gacaccatca atggcatcat agaagggagt atccgccatg acaagaactg
     4861 aatacctgac tcagctagaa ctctatctca agaaactacc tgaagctgac cgtatcgaag
     4921 ccatggacta tttcagagag ctctttgacg atgctggagt cgaaggagaa gaagaactca
     4981 tcgctagttt gggaactccc aaagaagcgg cccacgaagt tctatccaat cttctcgata
     5041 aaaaaatcaa tgaagcaccc gctcaaaaaa ataaccgaca aattttacat atcgccttgt
     5101 tagccctcct tgcagcacct atcggcattc ctctgggaat cgccatcctc gtgaccctgt
     5161 tcgcaattct tgtagccgct ttgactgtca ttctggcttt ctttgcagtt tccatactgg
     5221 gtatcatcgg cggattccta tttttagttg aaagtttcac tgtcctcgcc caagccaaat
     5281 cagcctttat cttgattttt ggttctggtt tactggctat cggtgcttct tcgctagttt
     5341 tacttggcat ttcctatgca actcgcttct tcggtctact cattgttcgt ctggtacaat
     5401 ttgttcttaa aaaaggaaag agaggtaatc agcatgcgta aatggacaaa aggatttctc
     5461 atctttggtg tggtgactac cgttatcggc tttatcctgc tttttgtagg tatccaatct
     5521 gacgggatta agagcctact ttccatgtcc aaagaacctg tctatgatag ccgtacggaa
     5581 aagctaacct ttggcaagga agtcgaaaac ctagaaatta ctctccacca acacacgctc
     5641 accatcacag actctttcga tgatcaaatc cacatttctt accatccatc tctttctgct
     5701 caccatgatc ttatcaccaa tcagaacgat agaactctga gtctcactga taagaaactg
     5761 tctgaaactc cgtttctctc ttctggaatt ggtgggattc ttcatatcgc aagtagctac
     5821 tctagtcgtt ttgaagaagt tattctccga ctaccaaaag ggagaactct aaaagggatc
     5881 aacatctcag ccaatcgcgg acaaaccacc atcataaatg ctagccttga aaatgcgacc
     5941 ctcaatacaa acagctatat cctccgaatt gaaggaagtc gtatcaaaaa cagtaaactc
     6001 acaacgccca atatcgttaa tatctttgat acagttctta cagatagtca gctagagtca
     6061 acagagaatc acttccacgc tgaaaatatc caagtccatg gcaaggttga actgactgcc
     6121 aaagattatc tcagaatcat cctagaccag aaagaaagcc aacgaattaa ctgggacatc
     6181 tcaagcaact atggttctat cttccaattc acaagagaaa agcctgaatc aagaggtacg
     6241 gaattaagca acccttacaa aactgaaaaa accgatgtca aggatcaact cattgcgaga
     6301 tctgatgata atattgatct aatatccaca ccaagcagac gttgacaaaa acgcttacat
     6361 ctgctactat ggaagcatat ttatctaacc aaaaggaggt tctaccatga aacaagaatg
     6421 gtttgaaagt aatgattttg taaaaacaac aagcaagaac aagcctgaag agcaagctca
     6481 agaggttgca gacaaggctg aagaaacgat agccgatctc gatacaccaa ttgaaaaaaa
     6541 tactcagtta gaggaggaag tctctcaagc tgaagtcgaa ttggaaagcc agcaagaaga
     6601 gaaaattgaa gctcctgaag acagtgaagc gagaacagaa atagaagaaa agaaggcatc
     6661 taattctact gaagaagagc cagacctttc taaagaaaca gaaaaagtca ctatagctgc
     6721 agagagccaa gaagctcttc ctcagcaaaa agcaaccacg aaagagccac ttcttatcag
     6781 taaatcttta gaaagtcctt atatccccga ccaagctcca aaatctaggg ataaatggaa
     6841 agagcaagtg cttgattttt ggtcttggct agtggaagcg atcaaatctc ctacaagtaa
     6901 gttggaaaca agtatcacac acagttacac agcctttctc ttgctcattc tgttttctgc
     6961 atcttccttt ttctttagta tctatcacat caaacatgct tactatggac atatagcaag
     7021 cattaacagt cgcttccctg agcagctagc tcctttaact cttttttcta tcatctctat
     7081 cctagtagcg acaacactct tcttcttttc attcctcttg ggtagtttcg ttgtgagacg
     7141 atttatccac caggaaaagg actggacgct agacaaggtt ctccaacaat atagtcaact
     7201 cttggcaatt ccaatcttcc tcactgctat tgctagtttc tttgctttct ttgatagcct
     7261 acgatttaca gccctcttgt gtgtgattag cattggaatc attctgcttg ccagtctcca
     7321 tatcattaca agaccaagtc aagcaagtga aaccgactcc ttctatcaat tattcttgtc
     7381 tgtccttgtg aacggagtta ttatcctcct cttctttgta gctgaagtgg cactgattgg
     7441 agattatctt cgtatcttgg cctttcttta aaattcaatc ctgtcatcct tggcaggatt
     7501 tttctatttc aaaaaagcaa gtcgattgac ctgcttctgc tttacttttc ttgtgctaat
     7561 gttttaaaat cttgtcctag gatgggttgt atttctattt gattggcgtc tagttggtgg
     7621 taaaaagatg ggggtaatac ctctaagaat tttgcatagt ccaagcgagc tatggattca
     7681 tagtcttctg gtttagagcc gtctcctgtg atttgaacca agtcaatctc ccactggact
     7741 tccttatcca ccaattgctc catataggca gcaggaacaa atggttctct cggtaaaacg
     7801 gtcttgacgc cttgagccaa atgataaaca ccgtgcactt gcccttctcc atcctgatag
     7861 aaggaaactc ttgcaaagta ggcatctgtc tcttgaaccg cacgcacacg cgcttcaaac
     7921 tgagccaaac catcttcctc taaaaagctt ttcaagtcct catgactaaa gaaaatagga
     7981 ttaaaaattc cttggcaaat cgtaaaacga actgcattat ctgtcagatg ggcttgaata
     8041 cttgcttgga aataagcttc aaaatcaaaa ccatctagtc cttcaatatc agtccctgta
     8101 taagcaagca gagcatctaa aaataacttg ataatccgcc agtctgtctt cgtgagtagg
     8161 tcaggaagat cgacacggta agccttttga ccatcagcat aactgacctt aaaaagaaat
     8221 tgtgattgcc ccactatcgc acattcgata tactcgagac gattaagagg ctgacggaga
     8281 tagactacat catagctatg tgactccaaa ccgtctagca aggccaagat cgacttggca
     8341 ttcaaaatct cttgttctcc taaaatgctc tgtttatttg gaataaaaaa tgttttcgcc
     8401 ataactggac tcctttgaaa tcgtttacat acagtatacc ttatttttct gaaagataca
     8461 aaaacaaact ttagattttt gagtacaaag catagaaaaa cagcccctga ggactgtttg
     8521 atcttataca gtagctgcct gatccaagct ttcaccgata gcggctaggc gctcaatcac
     8581 ttcagcttgt gtcaattcat tttttgaaac atagcggtta cgtgggtgaa cacggcactc
     8641 gtgtgagcat ccacgaaggt acttgtcttc attttcttct gatgtcaaga tacgacggtt
     8701 acagaaggga tttccacagt taacataacg ttcacatggt gttccatcaa accagtcttt
     8761 ccctacgatg gttgggttga catggttgac atcaacggcg atacgctcgt caaatacgta
     8821 catttttcca tcccaaagct caccttgaac ttctgggtct ttaccgtaag ttgcgattcc
     8881 tccgtgcaat tggccgacat ctttgtagcc ttcacggacc atccagcctg agaatttctc
     8941 acagcgaacg ccacctgtac agtaaaccac gacacgcttg tccatgaatt tttccttgtt
     9001 atcacggacc cattgtggta actcacggaa gttgcgaata tctgggcgaa tagctccacg
     9061 gaaatgtcct aggtcgtact cataatcgtt acgtgtgtca aggacaacgg tatctttatc
     9121 aagaagcgct tctttgaact cttttggaga caagtaagca cctgttgttt caagtgggtt
     9181 gatgtcattg tcaaagtcgt tgtcttccaa accaaggtgg acaatttctt tcttgtagcg
     9241 aacaaacatc ttcttgaagg cttgttcatt ttcttcgtca atcttgaacc agagttcttc
     9301 cattcctgga aggctgtgaa cgtagtccat gtatttttga gttgtttcat agtcacctga
     9361 aactgttccg ttaattccct cgtcagcgac taggatacgg cctttaaggc cgattgattt
     9421 acagaaagcc aagtggtctg cagcaaattg ctctgcattt tcaattggag tataaaggta
     9481 gtaaagtaag acacgaatat cttttgccat aagatttgtt ctcttttcta ttcttaaatt
     9541 ttctaaattt tttatttatc tacactagta tacctgcttg agaaaacgaa tgcaatttat
     9601 ttgactggaa attgtagagg gttctcgaaa tttcctgaat ggttaaaata aggacaagag
     9661 aaaacatgga tatctatatc cttgtgccaa aaaaaccact gccctcccca gaccaacctg
     9721 aggaaagcag tgattcttat tttaggagtt aggaatgaat acacgaaatc aatttagctg
     9781 attatttttt gtttttcaag aattcatcgt attgtttttg catttcgttc aatacttttt
     9841 cgtaggcacc ttcagatttc aatttttcca tcaattctgg aatcgcttta tctgggtcta
     9901 cagtaccagt gttgatagct gtatcaaatt gttgcattgt gttagcaata gctgagattt
     9961 cagatttcac attgtcagta ttgaagataa atccaagcgc tggagattct ttagcttctg
    10021 ccaattcttt cttagaattt tcgatttgtt ggtctgtaac gttttcgttg atgtaaagga
    10081 tccagttgtt accagtgttc catccaccca tgtgagtgtt tcctttgtag ccatcaagaa
    10141 cgcgaacacg gttttcttta ccttcaattt tttcccagtt cttgccttct ggaccgtaaa
    10201 caagaccgtt caagagttct ggattcgtat tcaagaggtt caagatttcc attgattttt
    10261 ctttgttctt agagttgttt gagatgacaa agttagcaac ttgtgttgtt tggtttttct
    10321 tgatgaagtt agtaattggt ttgatttgga tatctttgtt ggcaacacgt gaaagcaagc
    10381 tgttaccgta gtcagctggt cctactgttt cttcacgaac gaaccaagta tcttgttgaa
    10441 ggtcaaagga agtatcgctt gttgcgacgt cttttggaat gtagccagct tcatagaatt
    10501 tgtgaagagt cttcaagtgt tctttgaaac gaggcacttc gtaacggttt acaactttag
    10561 tagtatcgcc ttcaaggtcg ataacgaatg gaagaccgtt tgctactggg tagtcaaagt
    10621 tatcagatgg gatgaaaact ttaccaatag caaatggtac tacgtctgga gctttttctt
    10681 tgatttgttt caagactggc tcaagagttt cgtaagaagt aacacctgaa atatcgatac
    10741 catatttagc aaggagagtt ccgttgaagg caaagttttg agatgatgca acgttggctg
    10801 caactggaac agcgtaaatc ttaccattta cagtattacc cttgatgtaa gctgggtcaa
    10861 gtgctttgta aaggtcttta ccttcttttt tgtacaattc tgtcaagtca gcgtaagcac
    10921 ctttttgagc atttacaata tagttatctg caaaggcaat atcatagttt tcaccagatg
    10981 atgtgataac tgacattttc ttaccatagt caccccagcc aaggtattgg atatccaatt
    11041 tggcaccaac tttttcttca atgattttgt tggcatttgc taacaattca tccaagttgt
    11101 ctggtttgtc accgatttgg tacattttga taacaggttt gtcacctgaa tcagcagctt
    11161 ttttgctgtt acctgtcaaa tttccacaag cagcaagacc tgcagccaaa gcgactacac
    11221 tagcagatgc aaaagcatat tttttccagt ttttcatgat aaaaactcct ttttttattt
    11281 ttaaacttat aaacaatgta atgatcttat actcaatgaa aatcaaagag caaactagaa
    11341 aactagccgc aggctgctca aagcactgct ttgaggttgt agataagact gacgaagtca
    11401 gttacatata tctacggcaa ggcgacgttg acgcggtttg aatttgattt tcgaagagta
    11461 ttaacttcac acaagggaag ttgggaactg agaaatgttc tttttcaata agcactattc
    11521 tttcacacca ccgatagtca aaccttttac aaagtagcgt tggaagaatg gatataaaat
    11581 cgcgattgga agggttgcaa ccacaaccat ggccatacga cctgtttctt tcggtagagc
    11641 aactcccagt tgaccagtca agccgaccgc tttggcaatg tagtccatat tttgttggat
    11701 ttgcatgagc aaatattgca atggatacaa gttatcactc ttgatgtaaa gaagggcgtt
    11761 gaaccagtca ttccagaaac caagagctgt caaaagcgtg atggttgcga tacctggtag
    11821 tgacaatggc aaacagattt ggaagaaaat ccgggcctca ctggcaccat cgatacgagc
    11881 cgattcgaga atggcttctg gaatggtctt cttgaagaag gaacgcatca agatgatatt
    11941 gaatggtgag agaagcattg gaacaatcaa ggcccaaaca gtgtcaccaa gctgaagtac
    12001 acgggtcacc atgatataac ctggtaccaa accagcgttg aacaacatac tgagaaggac
    12061 gaagatggta aaaaatctgc gatacttaaa ggttgtccgt gaaatagcgt aggcataggt
    12121 tgttgtgata aagacatttg tcaatgtccc aactacggtt acaaagacag agatgaagag
    12181 ggcttgtagg attttatcct taaactgtgc caaaaactca aaaccgtcta agccaaattg
    12241 ggatgggaag aagctatagc cgtattggag gaggcttttc tcgtctgtca ctgaaataat
    12301 gataacgaat acaaaaggta ggatacaaga gagggcaatc aaacccgaaa tgatactgaa
    12361 gaagatatct gctttcttac tgaaggagtg aatgccgaca ttatcaattt tttctttttt
    12421 aattttcttt tttgccatat tctcctcctt tctagaacaa agctgagttt ggatcgactc
    12481 gtcttgcaag caagtttgat aggataacca gaatcaaacc aacaacggat tggtaaagac
    12541 cggctgctgc agccataccg atatctgctg tctgagtcaa accattaaaa acatatacgt
    12601 ccaaaacgtt ggttacattg taaagctgac cagcattgtg tgggatttga tagaagagac
    12661 cgaagtctgc gcggaagata tttccgactg caaggatggt caatacagtt acaagcggag
    12721 tcaactgagg aatggttacg ttgcgaatac gttgccactt gctagctccg tccactgtcg
    12781 ctgcttcgta gtaggttgga tcaattccca tgatcgtcgc atagtacatg acactgctat
    12841 atccaaaacc tttccaaata cctaggaaaa gtaggagata gggccagatg cccaggtcag
    12901 cgtagaaatt gacttctttg agaccaagac tttccaatag atgattgaac acccctttat
    12961 caatatttag gaaggcatct gtaaagaaac tgatgataac ccaagacaag aagtaaggga
    13021 acaacataga agtttggaaa atcttcacca ttctcttaga acggagctcg ctgaggataa
    13081 tggcaatccc tacagataca actaaaccta gaaagataaa gccaagattg tagaggacag
    13141 tatttcgtgt gataataaag gcgtctcttg aactaaataa gaatctgaaa ttatcgagtc
    13201 cgacccattt actatttatg atactatcta tgaaaccatt actggtcatg tggtagtctt
    13261 tgaaggcaac cacgttccca aatactggaa tgtaaaagaa tagaatcaac cagagtgccc
    13321 ctggcaaaac catcaagaga aagatccagt tgtctctcaa tgtttttgaa aactttttca
    13381 taatttcctc cctttttatt ttgatatcca tctaaaaatt cttttttaga cttttgataa
    13441 cgattacatt attagtatac tcctatttgc aggttaggtt aaactcctaa ttatagaaaa
    13501 aactccacaa attatgtagc agatttaaaa ctttatcacc actatcaaac aaatgtccta
    13561 aatcaattgt ttattttatc tctattagcc cagtgatggc gtcactctgt tataagcatc
    13621 caacaacggg gtatactgaa aaatctccag actagggaac tcagagatag ttcctaatct
    13681 ggagattttt aatatgttat taggcgtttg ctttcaactt agcaataacc tctttaagat
    13741 tatcaatcac ctctgcttca gtatgctcag agcctttttc atctgccaag aacaaaactg
    13801 ctttttgaag ttctttttga gagttttcaa ggacatcctt atctactgtt tcaaggtttg
    13861 agtctttaag aagtttactt aattccttgg ctaatttctt gagtttgatt tgcagactca
    13921 tcttctcctg ctgtttcttt gcccgctgtt tgtcctccat ccttagttgc tgactggctt
    13981 tccttaatgg actctaggga agcaatggca tctttgactg tttgcaagat atcacgtaaa
    14041 ccttgctctg tcaaactatc atctgcaaaa gctttcttag cctctgccaa aaccagacgt
    14101 gctgaatctg tggtaggatt cgatacacct gtcaatgatc tcaaaagatt ttctaaggtt
    14161 tgagtctgct tactaatact agactaaaat caaaaagtat tatataacag tgatatgaaa
    14221 tcaactaaag aagaaatcca aaccatcaaa acacttttaa aagactctcg tacagctaaa
    14281 tatcataaac gccttcaaat cgttctattt tgtctgatgg gcaaatctta taaagagatt
    14341 atagaacttt tatagtagtt tgaaataaga tgtgaacatc tctatcagga aagtcaaatt
    14401 aatttataga aatattttag cagccaaggt gtactgttat agattcaata cact
//
LOCUS       DAVLCS010000046        14414 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLCS010000046 DAVLCS010000000
VERSION     DAVLCS010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.046"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(779..1648)
                     /locus_tag="VXC78_001749"
     CDS             complement(779..1648)
                     /locus_tag="VXC78_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0583775.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIVA
                     AIAAVAVFKFLYL"
     gene            complement(1872..2549)
                     /locus_tag="VXC78_001750"
     CDS             complement(1872..2549)
                     /locus_tag="VXC78_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0583776.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKI
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEP
                     TPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGFF
                     KKKEDEK"
     gene            complement(2507..3613)
                     /locus_tag="VXC78_001751"
     CDS             complement(2507..3613)
                     /locus_tag="VXC78_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV0583777.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(3724..3978)
                     /locus_tag="VXC78_001752"
     CDS             complement(3724..3978)
                     /locus_tag="VXC78_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583778.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(4318..4764)
                     /locus_tag="VXC78_001753"
     CDS             complement(4318..4764)
                     /locus_tag="VXC78_001753"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0583779.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERTSIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDLLREVPTIFECLECFFKTR"
     gene            complement(4837..5162)
                     /locus_tag="VXC78_001754"
                     /pseudo
     CDS             complement(4837..5162)
                     /locus_tag="VXC78_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284991.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5396..7114
                     /locus_tag="VXC78_001755"
     CDS             5396..7114
                     /locus_tag="VXC78_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV0583780.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            7225..7572
                     /locus_tag="VXC78_001756"
     CDS             7225..7572
                     /locus_tag="VXC78_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0583781.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     ADTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(7850..8686)
                     /locus_tag="VXC78_001757"
     CDS             complement(7850..8686)
                     /locus_tag="VXC78_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0583782.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(8699..9328)
                     /locus_tag="VXC78_001758"
     CDS             complement(8699..9328)
                     /locus_tag="VXC78_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0583783.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASELLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(9338..9979)
                     /locus_tag="VXC78_001759"
     CDS             complement(9338..9979)
                     /locus_tag="VXC78_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0583784.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(10125..11354)
                     /locus_tag="VXC78_001760"
     CDS             complement(10125..11354)
                     /locus_tag="VXC78_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV0583785.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSNLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(11344..12510)
                     /locus_tag="VXC78_001761"
     CDS             complement(11344..12510)
                     /locus_tag="VXC78_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0583786.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            12654..13667
                     /locus_tag="VXC78_001762"
     CDS             12654..13667
                     /locus_tag="VXC78_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV0583787.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEKGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            13807..>14414
                     /locus_tag="VXC78_001763"
     CDS             13807..>14414
                     /locus_tag="VXC78_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0583788.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSRLPEIMSWDEYA
                     FTKGKMSFIAQDFEKLDIITVLEGRTQAIIRNHFLRYDRVVR"
BASE COUNT         4381 a         3077 c         2555 g         4401 t
ORIGIN      
        1 taaaaattta actaattaat agaaagtact aaatagactt atccttcaag gagttttcag
       61 cattatccat ccactcactt gctgaaaatg taaacagtct ctggtttata tagtaaaatg
      121 aaacaagaat agagcaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa
      181 gtagatgtgt actattctag tttcaatcta ctatacaacc tcaaaactgt gttttgaaca
      241 acctgcggct agcttcttag tttgcccttt gattttcatt gagtataaaa ttgcagataa
      301 aacgataaca atcataggac tcagcagagt caatgtaggt cgaagaatag cccccctaat
      361 cgcttatttt atagcaaaat gaaatagaaa ctgaacattt tgttgaggaa ggtaaatcaa
      421 ttcctcacaa tgtttgagaa agaagggagg actattccaa cttcaaccca ctataaagca
      481 gacttacaag atagggaacc catctccgat aatatatagt agaatgaaaa ctgcacaatt
      541 tgattggaga attcaaacca atttctcaca atgttttaga aacaagggtc tattatttca
      601 actgcaacct actatagtcc attgaagctg gaatagccca ctgagacttc taaaccactg
      661 ctggagagga gtttgtttag agtttctttc atttccctaa aaaatcaaaa agagagaacc
      721 agtctgatcc tctcttactt atagatggtg ctcactcaaa tgttaaagga gctatttctt
      781 agagataaag gaatttgaat acagctactg ccgcaattgc tgctacgata ggtgctacta
      841 ctggtaccca agaataccac cattttgaat cgcctttatg ctcaccaaga actgattttg
      901 gaaggaaagc atgaaggaga cgtggtccca agtcacgggc tgggttcaag gcaggtcctg
      961 taggtcctcc aagtgatgtt accaaagcca taacgaggaa tccaagtgcc aagtgagcca
     1021 cagaaagtcc tgaagcagtg tgtggagcca cctgtgcttt aatagccaag tcagaaaaat
     1081 caactgtttg tcctgcttct attgcctttt gtttcatgaa ttgaagcact tcagcaccaa
     1141 agaagttttt agtcaaacca agagctgcaa agaacaaaac aaatgaacca acaaactcat
     1201 taatcaaacc attgacagtt gctgcatagc gactttcttt tgtaccatgg tcaatacttg
     1261 aaatagttga gaaagttccc aagatgttat ttgggttttc agttttcaag tagaatggac
     1321 ggtatgttgc cacaactaag gcttggccaa agatagctcc caagacttgc gcgataatat
     1381 aaggtaccac ttgtgcccaa gggaaaagac cgctaactgc aagccctaga gtgaaagcag
     1441 ggttgatgtg attcccagat acgttaccaa acatcaaggc tgggatcata acccccatac
     1501 cataaccaac agcgatgacg atccagccac tttggtgacc tttcgtacct ttaagttcaa
     1561 cgttggcaac tgcaccattc ccaagaatga tcaaaatggc agttcccaaa aattcagtgg
     1621 catacttcag tgcccatgtg aaatccattt gctagattct ccttaaaatt ttttagatat
     1681 tccttatttt atcaattttt accctattta gcaactgatt tctggaaata tttttaaaaa
     1741 aataggattc atagtttccc agttcaacgg acttgtaagc gtttttattc ttcacgaaag
     1801 acctcgttct caaaaccagg aaaaaagccc acatctgtga gcttttcctg gttcctagat
     1861 tctaaaatct attatttttc atcttctttt ttcttgaaga atcctaatcc tagaccagct
     1921 aacaaggtca tgataccagc actagccaag gtagcattag cttctgtacc tgtgtttggc
     1981 aattcctctc tcttacctgt ctcataagtc ggaacttctg ggtctggatt cactggagtt
     2041 tcagtttttg gagtacctgg ttctggagtt ggctctggta ttggagtctc ttgatttggt
     2101 agttctgggt ttggtgtcgg aacacttgga tgctctggat ttggttgtgg gattggtttt
     2161 tctggagtcg gttcacctgg agtacctggt tcctgaggac ttggaatttc tggtttttct
     2221 ggagttggtt tatctggtgt tgataaacgg tcatacctta ccgttatttc tttatcacta
     2281 gagtctgacg taacttcttg tgattcaact gttggaatat ctggatcttt gtacttgtca
     2341 atcttaccag atacaacctc gtcccagttt cctgttgtcc attcaccgta ggttacaact
     2401 cccgtgacct tgttctcaat ttttgtacgg cttaaggtta caggttgaac aacatcttct
     2461 tttacatttt ggttcgtaac tttatcaacg taatgaatga tacgcgttat agtcttcgtc
     2521 tcagtagagg ttgctgtttt gggaaccact gtttcctcaa cattctcacg gtagtaatag
     2581 tcaactgttg caccgtcttc tggtacgcat ttgcaggagt tgctaccaag gtgtatgttg
     2641 ttttccttgt gataactcgg tcttctttgt cctcagttgt tgttttccct tcaatagttt
     2701 ttgattctgt ggtatactca gaacctatcg ctaaatcagc ttttataaca gactctgcca
     2761 acttctcttg gctaccttct ttatagtaat tggctgttac tgtagcagtg gttggcgctt
     2821 cgctttctct ataaactaag gtcactgttc taccttcgct tacaatattc ccagttaaac
     2881 ttgcagaatt tgtatctgct tctttaaaag tataatattt tccgtcagta gtagtcatgc
     2941 tactgagttt tttatctgtg acattgtagc tggtaccaat cagttgtttt ttattggtaa
     3001 tgtaggttcc gtcactttct ttttctccaa ttccagtatc atttttcaat gatagcaaac
     3061 gcccttgttc atcaacatag cgaactttca cattttctga gattagttct gccaattctg
     3121 aggttttttt ctttttcttg atttcttcgg ttattttccc tttctcttct tcgggaatat
     3181 ttagttttgg aatgattttt tcaacaacgg ttcgtgatgg ttccacagta tcttggatga
     3241 ctgaaaagtc agctagaatt gggagattat actgaacacg gtgactttga gtgtttactc
     3301 ctactctttc attattctct gaaaatactt gtacggtata agaaacaaca tcttttccta
     3361 atagaacatc cccagtagag aaatagccgc cttttcctag tttgctatct ccagagccca
     3421 cttctttcct aatcttatca gatagttttt taccagtcag tacattcgtt cgcacaatcc
     3481 ctttgtctac ccctacaaag tgggagaact ttttgaactc ttcagaacca gatctagccc
     3541 aaccattatt aagggcattt gcttttgtat ttgtattctc tctcaaaagt ttggcgatta
     3601 gaattatatt catcggcact tagagttgct gctatatctg actcttgaat accaacttcc
     3661 ttactaccat ttctagcggc agtatatgtg tatttatctg tttctacttc tagctgatta
     3721 tccttaacat gataggtaat tttctcctgg tataagagtc ttcagtagtt tatatactct
     3781 gtcatcatct ttagctttag aagcagctga gtttagccaa gttggggtat taggagtatc
     3841 tttatcagcc tgtttcaaga cattattcaa gtcatttgct agcctattgg ttatcctcac
     3901 tgtgaaagtt ttcttccagt ctgaaccact tttattagac ttagatatgc tcatgaaatc
     3961 ctggtcaaca ttcaacacaa tatcgccttg ttttttagca tcttccgttg cttctgcttc
     4021 aaattgatca tggagttttt gttgctctgg tgtatagttt ttttatttac acgatttaat
     4081 gtactatttt ttattttagt attaagaact ccattaatac gatttttaaa ctctgcttca
     4141 aaaaatccct taatttgttg gtgcgcaagt tcaacattca aacctttctt atacaagtct
     4201 tcattctgaa cgatttcggc tacacggtga atggtttgat tgtataccgt cttctcttaa
     4261 ccagcagtat ccttagtttt aatgactact cgataggttc ctttagaacc gttatagtca
     4321 tctagtttta aaaaagcatt ccaaacattc aaaaatagtt ggaacttccc ttaataaatc
     4381 cgtcactttc tttttcaaga tagcccaagc ttgctcaata ggattcaaat ccggtgaata
     4441 aggtggtaga ggtaagaaaa agtgtttatc ttggatgcag agttcatcca aaatgttctt
     4501 gggatgaaaa ccagcattgc ccatgacaat aacatgaggt gtcttcaaag caggtaggag
     4561 ttgcgttttg aaccactcca caaagaaatc gcttgtcatg cttttcttgt aaatcatggg
     4621 agctataaac tctccgtcta cttgtcctgc aacaattgaa gttcgctcaa aacgacgtcc
     4681 gctaatcttt tcatagactt tctcccctct aggagcccct gcataaggac gatagagata
     4741 gcggtcgatt cctgtttcat caatataaac aggtgctagg tgctttaaac tattaaaatt
     4801 cttaagaaat aaggctactt ttctgggtct tgttccttaa agctcctcat ctttttttaa
     4861 agtgacctta atctgcttta aagctgccca tactgaagga acagcacaat caaaatgtgc
     4921 cgcaatttcc cgtaaaaaag catctggatg agcctctaca aaggctttca attcctctaa
     4981 aggaatcttt cggtttttga cgactcgctt tttcctctct atgtgttctt gttcacgtct
     5041 ttcttttccc acgtgaagag agttctgacg ccaacaccaa aaaacttggc tgcctcgaca
     5101 tggctgtgcc cctctttgat gtaatctaat gctcgctgtt taaaatcagt actatatgcc
     5161 atagctttat tataatatgc ttgtttaaaa ctaagtaact atatcaatgt tttgttatga
     5221 gaagacttac tttttttact gaaattgaat ttttcctagc ctcaacatca tataacccca
     5281 aaattcaatc tgacctggtt tgaagagatt ttcgaagcag ataaggtttt actaaaacta
     5341 aaaaaaatga tataattaaa ctgattaaat gttttaaaaa taaaggagaa tttgaatgtc
     5401 ttaccaagaa aattaccaga aatgggttga ttttgtggag cttcctgact accttcgtca
     5461 agatttggaa aatatggacg aaaaaactaa ggaagatgcc ttctatacaa atcttgaatt
     5521 tggtactgca ggtatgcgtg gcttggttgg tgctggtaca aaccgtatca acatctacgt
     5581 tgttcgccaa gctactgaag gattggctcg tttgattgag tcaaaaggtg gaaacgagaa
     5641 agaacgcggt gtagcaattg cctacgatag ccgtcacttc tcacctgagt ttgcctttga
     5701 atctgcggca gttcttgcta aacacggcat caaatcttac gtatttgaaa gccttcgtcc
     5761 aactccagaa ctatcatttg cagttcgtca tctcaactgt ttcgcaggta tcatggtcac
     5821 agccagccac aaccctgctc catttaacgg ttacaaggtt tacggtgaag acggtggaca
     5881 aatgcctcca cacgatgcgg acgctttgac tacttatatc cgtgcaatcg aaaacccatt
     5941 tgcagttgaa gttgctgatg tggaaactga aaaagcttct ggcttgattg aagttatcgg
     6001 cgaagctgtt gacatagaat accttaaaga ggttaaggac ataaacatca acccagcctt
     6061 gattgaagaa tttggtaaag acatgaagat tgtctacaca ccacttcatg gtactggtga
     6121 aatgttggct cgtcgtgctc ttgcccaagc aggatttgac tctgttcaag ttgttgaagc
     6181 gcaagcaact gctgacccag acttttcaac tgtaacatct ccaaacccag aaagccaagc
     6241 agcctttgcc cttgctgaag aacttggtcg tcaagttggt gcagatgttc ttgtcgcaac
     6301 tgacccagac gctgaccgtg ttggtgttga agttcttcaa aaagatggta gctacctcaa
     6361 cctttcaggt aaccaaatcg gtgctatcat ggctaaatac atcttggaag ctcacaaaaa
     6421 cgctggaact cttcctgaaa atgccgctct ctgcaaatct atcgtttcaa ctgacttggt
     6481 aacgaagatt gctgaaagct acggcgcaac tatgttcaac gtcttgacag gtttcaaatt
     6541 tatcgctgaa aaaatccaag aattcgaaga aaaacacaac cacacttaca tgatgggatt
     6601 tgaagaaagc ttcggttact tgattaaacc atttgtacgt gataaagatg ccatccaagc
     6661 cgttcttgtc gttgctgaac ttgctgccta ctaccgttct cgtggtttga cacttgctga
     6721 cggtatcgaa gaaatctata aagaatatgg ctactacgca gaaaaaacaa tctctgttac
     6781 tctttcaggt gtcgatggtg ctgaacaaat caaagcgatt atggctaaat tccgcaacaa
     6841 tgctccaaca gaatggaacg caacagctat cactgtcgta gaagacttca aggcacaaac
     6901 tgctactgtt gctgacggta ctgttacaaa cttgacaact cctccaagtg atgtgttgaa
     6961 atacacactt gctgacggtt catggattgc cgttcgccct tcaggtacag aaccaaaaat
     7021 caagttctac attgcagttg taggggaaac caacgaagaa tcacaagcta agattgctaa
     7081 catcgaagca gaaatcaatg catttgtaaa ataaagacct ataaaagatg agaccaacca
     7141 acctcatctt ttttcgtatc aaatctaagc aattttagaa actttatggc atactagact
     7201 tatcaatgaa agcgaggtaa tctcatggaa caatttttgg ataacatcaa agaccttgaa
     7261 gtcactacag ttgtgcgtgc gcaagaagct cttgataaaa aagaaactgc aaccttcttt
     7321 atcggtcgca aaacttgccc ttactgccgt aaatttgcag atacattgtc aggtgtcgta
     7381 gctgaaacca aagctcacat ttacttcatc aatagtgaag aaccaagcca actcaatgat
     7441 ttgcaagcat tccgctcacg ctatggaatc ccaactgtac caggttttgt tcatattaca
     7501 gatggacaaa tcaacgtccg ttgcgactct tcaatgtcag cacaagaaat caaagatttc
     7561 gcaggattgt aaaaaatcag ctaacaagtc ttaaaatcac aaaaacgcat aatgtaaggt
     7621 gcaaaaacct tgatattatg cgttttattg ttcctaaaac agttacatca gcatttcatt
     7681 acagaacatt ttaattttgg aagtcaaatc aatttttaac aatgttttag aaatcacagt
     7741 gggctattcc atattcaatt atccatattc aatcgctatt atcgttttcc tagattacaa
     7801 aaaaactacg ttttgctaat caaaacgcag tttcagccac tattttatct tactgtcctt
     7861 cttttacttc tttggttgct acatcttctc caaaccattt ttggctgatt tcttggaact
     7921 tgccgtcctt gtaaagacta gaaaaagctt catttatctt cttaaccaag gttgtatctt
     7981 ccttacgggc tccaaccgca aaagcttctg tttctagtcc aactgtaaag acattataat
     8041 cgtttaaaac accttctgct tctaaataat agtttgcata gacacggtca atcaatagac
     8101 catcaattcg atcgtttttc aaatcaatca aggcttcatt aaaggtttgg tattgattcg
     8161 cttccttatt agcgacaata ttcttcaaaa tttctggatt tgcttcaaag tccgcataac
     8221 cagatgaacc agcttgagct cctaatgtct ttccagtcat atcctttgca gtcgtgatac
     8281 cagatgattt cttcgtaacc aatacctgct cattcttcat atatgagtta ctgaaagcca
     8341 ccttttcacg gcgttcgtct gtagcggaat agccattcca aatcagatca atcgttcctt
     8401 ttgtcaattc agcttctttc aaatcccaat caatcggttg ccaatttacc gtgattccgt
     8461 atttttcaaa aacagctgta gctaaatcaa tatcaaatcc tgcataagaa ccatctttct
     8521 gagcaaatcc cattggaaca aaagtactat caaatccaat agtaatagac ttgttagact
     8581 ggtactttga ccaattatct ccactagttt cgctagaatt tttcccacaa gctactaaga
     8641 acaaagcagt catcagactg actaatacaa gcatccattt tttcatccat ttttcctcct
     8701 atttaggttc tactttcaat aatacatctg cgatattttc agcaaactgc aaatcatggg
     8761 taaccacaat ctgggtcatc ccaagttccc tattttgcaa gattagcttc tccacttcca
     8821 aacgtaattc tggatccagg gcagaagttg gttcatcgta gccaatgatt tctgggtcaa
     8881 tcatcatagc acgcgccaaa gccacccgct gcttttgccc accagatagt gagaaaggat
     8941 aggcctctgc gtgtcctcct agtcctaact gttccaagag ttcactcgcc ttcttctcag
     9001 cctcttcctg cttcattccc atggtcttca caggcgataa agtcaaattt tccagaactg
     9061 atagatgagg aaatagttga aaatcttgga agacaaatcc cagtaggttg cgcttctgca
     9121 attcatccag ctctaaaggt tgtccattat aaaagatttg ccctgaatca atggtttcaa
     9181 gacctgcaag catacgtaaa agagttgtct tacctccacc agaaggtcca acgatagcca
     9241 ggatttgctt ttcaggaata cttagactga aatcagacag gatttgtttg tctccaaaga
     9301 ctttattgat atttcgtaat tctaacatag ctgcccccta tctataataa ctgtactttt
     9361 tctcaacttt tttggaaata attgtcacaa tcccaattaa aatcaagtaa atggctcctg
     9421 ccaagaacat aggaaccaga ctagcatcgc ggttagcagc tgttcgacta gccaagataa
     9481 ggtctgaaat tccgagagca tagaccaaag aagtatcctt gaccaaactc ataacttcat
     9541 taaagacact aggaagaacg atcttggtca cttggggcaa gataatatag cgcactctgt
     9601 caaaagggct aaacttcaag accttggcag cctcatactg tcctcttgga atagtgtcaa
     9661 ttcccccacg gaaaatttct gcaaagtaag ctgcatagtt gagaacaaag gcaataatag
     9721 ctgcaggaag gcggtctaaa cgaatcccaa tacttgggag cacataatag ataaaaatca
     9781 gttgcaagag taagggggtt cctcgcataa cccagatgta aatgttaatc agataatgga
     9841 ggggcttcca atggacttgc aaggcaaagg caatcaaaac gcccaaggga atcgaaaata
     9901 gcaagaccag tgcaaagacc tgtacagtcg tgctcgcacc attcagtaaa ctcggtaata
     9961 tctcaaataa ataagacata ctgcacctcc taaaagtaat tgttcctatt atagcatgaa
    10021 taaacaagat taccaagtat ttttgtaaaa agattctacc atatacaaat aaaaaccgta
    10081 gctatcaaaa gagataaact acagttctat atgtttaaac attcttacaa tctctcaaac
    10141 agttcttgca tttgcacatc atctggaacc agttttaagt aagtgtgagc atggactttt
    10201 gcttcttcaa aatgtcccaa ttcacgcaag agatagatat agtgttccag aaattctgga
    10261 ttgtccttca aatctcctgt caactcttga taatgctcat aagcagtatc caaatcgtcc
    10321 atttcttgat aagaacgagc aatcatccac ttggtcaaaa gattttctgg ctcctcactc
    10381 tgcaagtcta gaatatcctc ataacgctcc tgctccagat aaatagtggc taaacgaagc
    10441 aagatttctt ctgtatcctc agcgtcttct tttgcagtaa ggagataatt ttctgcacca
    10501 ctagcatcat gcaattcata agaaaattgt gaagcagcta gcaagaggcg agtttcaaag
    10561 ggatttttct ctaatccttg cttagcgata cgcagggctt cttgaacttg atgttcctta
    10621 tgtaaagcct gactgtaccc atactcatag ccttcaaagt caggagaaat ggtatcaagc
    10681 tgcttaaagt agagggtggc tttttgatat tcttcttgat caaaataaag actggccaac
    10741 tcaaaagctg ttaagtcatc gtattctaac tccagggctt tttctaaaaa ctcagtagcc
    10801 gtttcaaatt tccctaactg agcataggca aagccaattc gttgataggt ggaaatgccc
    10861 gtttgctcat aaatcgagcg attatctaac tgggcatagg cttgaatagc cgcttggtaa
    10921 ttttccaact cactatccaa ctctgccaaa cccaatatca agagagaatc ctctgagtag
    10981 gtcaaggcct ccaataattt ctcacgtgcc acatctgtca aaccttccag ctggtaaagg
    11041 tctgccttca aaaccaaaga cgagacatac cagtcactgt cagcttggat ttcctcaaga
    11101 taggtaaagg cttcttctat ttgaccatcc tcgctagcaa ttgcagctag attaagatga
    11161 acctctggaa aatcctctac aattttcagg taaatttcct tggcctgagg atagaaacca
    11221 atcccttcaa gataagttgc caactcatac agaagattac ttgaatcatt ttctaaagct
    11281 ttggcgaaat aatgctcagc cttagttaaa tcttgctcct ccaaagcctg taacatctgt
    11341 tgactattgt tcactcttga cttcctcacc ctctaattca tatagaccac tgactacctt
    11401 ataccattcg aaaatggctg aaatgacaac cttagcagag gcataaaccg gaataccaag
    11461 taaaactccc cagataccaa acatagatcc tgaagttaac aaaacaaaga gaacattaat
    11521 agggtggatg tttaattgac ttcccaaaat caatggagag acaaaacggc cttcaatagt
    11581 ttgttctacg ataaagacaa tcactacttt caaaagcatg actggaccag caatcaaacc
    11641 caatactaga gcaggaagca tggctagaaa gctaccaaga taagggacca gatttaaaat
    11701 accagcagta acccccagcg taaccgcata gcgtagacca ataatcttga agaagatgat
    11761 aaacattact gctacaataa tagccactgt cacttgccct cgaacatagt tggacaactg
    11821 ttgattcaca tctgatagaa cttgtccaac aggttccttc aattttcttg gaatgaattg
    11881 ggtcaaatag ttacgcaagc ctttcccatc acgcaagaga taaaagagca tgaaaggaac
    11941 gataatcaag gcaacaatca cttgagaagc tccgctaata aaggcactca cccagttgac
    12001 tgcctgagat gaaaccttac ttgccaaaac tgtagcctgg ctagaaaaat tggtcaaaac
    12061 ttgctctaat tgaggtctga aatcatctgg caggtgctgg gctaccaatc cattaacaat
    12121 cctatctata tcttctaagt aaacaggaac gtttcttgca aaggtcaaaa cctgacgttg
    12181 cagatttgga atggcgactg ccaagcccca aatgataaag agagcgatga taacaaagac
    12241 aatagtgata gctataacac gattaacctt atgcttctcc atccaatcaa caataggatt
    12301 caacaaataa tataacaaac cagacaaaat gactggcaac atcacaactg ctaaaaagtc
    12361 taaaacaggt gaaaatagaa aactaatctt acttaaaata aaaagattca gtcccaataa
    12421 taaggttact aaaaataccg taattgcctt gttatctaaa aaccacttga aaaaccaaga
    12481 taggctaaaa tgtttctctt tttgctccat aaatacttcc tttctattgt tctctcatta
    12541 taccattttt gaaacaaaat aactcttttt taaagtgctt acatctaatt ggatatcttt
    12601 aatttacttg tttttgtgat ataatagtct tatctttaca cagaggtata gtaatgaaag
    12661 aaactgttta ttttggaact tatacacgtc gtacttctca agggatttac aaggcagact
    12721 ttgatacaga aactggtcag ctttcaaatc tagaactttt tgcagctgag ccaagtccaa
    12781 cctaccttgc ctttgaccag caccaacatt tatacactgt tggtagccaa gacgataagg
    12841 ggggaattgc agcctatcaa actgacggga ctgtgttaaa tcatgttgtt gaaaaaggag
    12901 ctccccactg ttatgttgct gtcgatgaaa agcgtgattt ggtttacgca gccaactatc
    12961 acaagggaca agtccttgtt tataaacgcc aggaagatgg tagtcttcta cttagtgata
    13021 tggatcaaca cagtggccaa ggtccacatg aaaatcaagc ttccccccat gttcactata
    13081 cagatttaac acctgaccac tatctagtga cctgcgactt gggaactgac caagtcatca
    13141 cctatgacct cgatcaagaa ggaaaattat ctaagctcta tacctatcac agcaagccag
    13201 gagcaggctc acgccatatc attttccata accactataa aatcgcttat ctcatttgtg
    13261 aactcaatag tactatcgaa gttttaatct acgatggcgt tggcgaattt gaacgtatgc
    13321 aggtcatttc aactttaccg gaagcttacg aaggctttaa tggaaccgct gctattcatc
    13381 tctctaaaga cggtaaatac ctctacgctt ctaaccgtgg ccatgattct atcgcagtat
    13441 ataccatcct tgcggacggt agcttagagt tattagaaat cgttccaacg catggtcaga
    13501 ctccacgtga ttttgatttg acacccgacc aaaaatttct cattgttgtc catcaagact
    13561 ctgacaatgc aactgtcttt aaacgtaatt gtgacaatgg tcgtctagca gaactctcca
    13621 acgacttcca tgttcccgaa gcagtctgca tccgttttgc tccttaaaac accataaaaa
    13681 atggttctat aatatttgta gtgggtaaat cccctatgga tattatggag cctatttttg
    13741 tgtagaaaaa aagtcccata tgacctataa tgaaaagcga caaaacaact cattagaaag
    13801 aatcatatgg aacaattaca ttttatcaca aaattactag acattaaaga ccctaatatc
    13861 cagattttag acatcatcaa taaggataca cacaaggaaa tcatcgccaa actggactac
    13921 gacgccccat cttgccctga gtgcggaagt caaatgaaga aatatgactt tcaaaaacct
    13981 tctaaaattc cttatcttga aacgactggt atgcctacta gaattctcct tagaaagcgt
    14041 cgattcaagt gctatcactg ttcaaaaatg atggtcgctg aaacttctat cgtcaagaag
    14101 aatcaccaaa tccctcgtat catcaaccaa aagattgctc aaaagttaat tgaaaagatt
    14161 tctatgactg atattgccca tcagctttcc atctcaactt caactgttat tcgtaagctc
    14221 aatgattttc actttaaaca tgatttttcg cgtcttcctg agattatgtc ttgggatgag
    14281 tatgctttta caaagggaaa gatgagcttc attgcgcaag attttgaaaa gctcgatatt
    14341 atcactgttc ttgagggtag aacacaagct atcattcgaa atcactttct tcgctacgat
    14401 agagttgtcc gatg
//
LOCUS       DAVLCS010000047        14301 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLCS010000047 DAVLCS010000000
VERSION     DAVLCS010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14301
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.047"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(67..1356)
                     /locus_tag="VXC78_001764"
     CDS             complement(67..1356)
                     /locus_tag="VXC78_001764"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV0583789.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1434..2681)
                     /locus_tag="VXC78_001765"
     CDS             complement(1434..2681)
                     /locus_tag="VXC78_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV0583790.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2872..3723)
                     /gene="rgg"
                     /locus_tag="VXC78_001766"
     CDS             complement(2872..3723)
                     /gene="rgg"
                     /locus_tag="VXC78_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV0583791.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            3847..4188
                     /locus_tag="VXC78_001767"
     CDS             3847..4188
                     /locus_tag="VXC78_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0583792.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            complement(4397..6100)
                     /gene="ilvD"
                     /locus_tag="VXC78_001768"
     CDS             complement(4397..6100)
                     /gene="ilvD"
                     /locus_tag="VXC78_001768"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV0583793.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAEATLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(6333..7265)
                     /locus_tag="VXC78_001769"
     CDS             complement(6333..7265)
                     /locus_tag="VXC78_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV0583794.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFSSRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(7262..8119)
                     /locus_tag="VXC78_001770"
     CDS             complement(7262..8119)
                     /locus_tag="VXC78_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0583795.1"
                     /translation="MILSENREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(8123..9469)
                     /locus_tag="VXC78_001771"
     CDS             complement(8123..9469)
                     /locus_tag="VXC78_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0583796.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(9482..9766)
                     /locus_tag="VXC78_001772"
     CDS             complement(9482..9766)
                     /locus_tag="VXC78_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0583797.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(9770..11800)
                     /locus_tag="VXC78_001773"
     CDS             complement(9770..11800)
                     /locus_tag="VXC78_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0583798.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            11991..12998
                     /locus_tag="VXC78_001774"
     CDS             11991..12998
                     /locus_tag="VXC78_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0583799.1"
                     /translation="MTEKLINSKPNGVFALILIELTIILGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            13001..13201
                     /locus_tag="VXC78_001775"
     CDS             13001..13201
                     /locus_tag="VXC78_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0583800.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            13353..13535
                     /gene="rpmF"
                     /locus_tag="VXC78_001776"
     CDS             13353..13535
                     /gene="rpmF"
                     /locus_tag="VXC78_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV0583801.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            13551..13700
                     /gene="rpmG"
                     /locus_tag="VXC78_001777"
     CDS             13551..13700
                     /gene="rpmG"
                     /locus_tag="VXC78_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0583802.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(14192..>14301)
                     /locus_tag="VXC78_001778"
     CDS             complement(14192..>14301)
                     /locus_tag="VXC78_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0583803.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         4607 a         3030 c         2452 g         4212 t
ORIGIN      
        1 tatccacaac ctcaaaacag tgttttgagc aacctgcggc tagcttccta gtttgctctt
       61 tgattttcat tgagtataaa atcctagttt ttcaaagatt tctgagaagt tttggctgat
      121 tgtctcaagt gacacttgca cttcttctcg ggtttggttg ttcttgaccg tcacttgtcc
      181 gctttcgact tcgctctctc ctagggtgat gagggtctta gccgcaaaga catctgctga
      241 cttgaactga gctttgagct tacggttgag gtaatcacgc tctgctttga aaccttgttg
      301 gcgaagagct tggactagtt ctagggcttt gacatttgct ccatcaccca agactgcgat
      361 atagacatct agggcgtttt cgatagggag ggccacgcct tgtttttcaa ggatgagaag
      421 caggcgctct acaccaagcc caaaaccaaa tccagcagtt tcagggcctc caaagtaagc
      481 aaccaaacca tcgtagcgac cacccgcaca gactgtcaag tcattgccct caatctctgt
      541 gataaactcg aaaatggtgt ggttgtagta gtccagacca cgcaccatat tggtatcgat
      601 gatgtaatct actccaagat tttccaacat ctgacgcaca gcatcaaaat gagtttggct
      661 ttcttcatca agaaagtcca agatagacgg cgcattctct actgccacct tgtcttcttt
      721 ttccttagag tccaagacac gaagaggatt ttcctccaag cgacgttggc tatccttaga
      781 caaggtctcc ttgagcggtg tcaaatagtc aatcaaggct tggcggtagg ctgcacggct
      841 ctcaggattt ccaagagtgt tgaggtgcaa tttgacacct tgaataccga tttccttcaa
      901 aaaatgggct gccatagcga ttgtttccac atcggtagct ggattgctag agccaaaaca
      961 ctcaacacca atctggtgga attggcgcaa gcgccctgcc tgtggacgct cataacggaa
     1021 cataggtccc atatagtaga acttgcttgg cttttgcact tctggggcga aaagtttatt
     1081 ttccacatag gaacggacaa cgggtgcagt tccttctgga cggagggtaa tatgacggtc
     1141 acccttgtca taaaaatcgt acatttcctt ggttacgata tccgttgtat ctccgacaga
     1201 gcgactgata acctcgtaat gctcaaaaat aggcgtgcgc acttctgcat agttatagcg
     1261 cttgaaaatc tcacgggcaa agccctcaac gtactgccac ttagcagact cagcaggtaa
     1321 aatatcctgc gttccttttg gtttttgtaa tttcataggg aatcctcttt aaacttaata
     1381 gtcttatttt accacaaata aagggattaa aacagtgaga aaaaaattag gatttagata
     1441 tcatttttga gattaagaat tgtcaaaaaa atagctagca aggaaagacc aacaaatagc
     1501 atccaagtca actgtatatt ccatacggct actagtgaaa aacaagctgt tcccacaggt
     1561 atggataagg taaacaatag acctaaaaaa ttactagtac gagctagaac ctctggagct
     1621 agatttttca tgagcatggc actaatcttt ggttgaactt taccagacac atacagagta
     1681 aagaagagaa atagcaaacc aagcacgact tgattgaata aattagccaa accaactaga
     1741 ctaagtccta cggtcgccca catcatcaat ctaggcaagg actgcttccc aaaataatca
     1801 ttgcccgtaa ggctactgat gataactgct actaaaacac agaattgatt gataaatagt
     1861 gcctctgtat aagaaaaatt caagagagaa tggctcaaaa agaagatatt ataaattcca
     1921 cccaaagcgc cacccaagga attaataagc aagacagcaa agagcataaa accaaagttt
     1981 ttctgtccac ttttaagaaa aacgagacgt aaatttcggt aaattgttag gaactggtct
     2041 ttgatagaaa gcttctcatt ttttaagttt tcaccatcag cagatgacat tgacaggctc
     2101 aatttgcttt ttcctaaaaa gaggatagtg gctgatacta ggaaaaagca ggcattgatt
     2161 cccgcaacga gagaaaaatt gttgaccgat agagctaaga gccagactcc gaaagcttga
     2221 ccaccaatag ctgaaatata ggtgatgaac tgtgaaaaag aataagcctc catcagatca
     2281 tcttcagcta ctttttcctt aataagaggc atacgcaggc cacctgcaaa atcactgatg
     2341 atatcactaa tgacattgat caaacacagg ctagaaaagg caaagagact agcttgctga
     2401 acaactaggg ctgctagaaa aaatagaacc gcctgaaaca aaccgctata gaccatccat
     2461 ttgaccttgt ccctcgtgta atctgcccga atccctgcaa aaactgtaaa gagggtcgga
     2521 agaatcatga caatattcgc catagcaaca gcaaaagatg cttgtgacaa ggtcgatgca
     2581 tagacgataa agaccaggtt gaaaatcgaa gcaccaaaag cattgaagaa gcgtgataaa
     2641 gtcaaaattc tataagctgg atttctaaac aatagtttca tagataatct ccctccttgt
     2701 tctaagttct acatcaagaa tagctttagt atagcactta tgaatttgcg aaacgattct
     2761 tttgaatata tgcaacaaac aaaatgagca aaaaaacgat agaacttttg taatgacctg
     2821 agagagggca acagttctat cgcttcaaat tttttcttgg tttgcagata ttcaacattc
     2881 ggtcgtattt ctatagtatt cggcagattt attacagcca agcatctcaa aaatacggac
     2941 agcatcctcc atctttttct ggccttcctt gactctacct tgcttgctat caaggagacc
     3001 ttctgcccac agataaacaa ttcggaaata ggtctcattt tccttgtaga aatgctcttc
     3061 gataacacgt ttaaaataat aggcattggt aaattcttca cactcaatac tagctaaaaa
     3121 gccattcaat agtatagtat gaaaaaggtt tcgattgcca gacatttcca ttagaaaatc
     3181 agatttacgt accatttctc gtacatatct agtaaaaaga gaaacagata aaaatggaga
     3241 actgactgaa aataaattga gttcatagat tccccagatc tcggtagaaa acaaataatc
     3301 atgaaggact tttccttcct ctgctgttaa ctctaccctt tcatccatgc tcttcatata
     3361 agacttgatc ataatggcat ttagaatatg tttctgtttg ttgtgagaat gggcatgctt
     3421 ttgatactcc ctgcgatata agtcctcaag aggtgctata ttctttggtt ccaagacatc
     3481 tgtaatttct tttctcaact cagaatctgt atcatactgg aaacctctcg ccagaaagag
     3541 gatctcctcc acactggcag atatattttc cagagcaaat agaaactttt ccaccgaaag
     3601 ctcactctga cctgtttcaa aacgggacaa catagacggc gaaaattgtc ctccggttgc
     3661 ttgtctcagt gagatatttc ttgactctcg taattgtcta aagacttttc caatctgctc
     3721 catagacttc cccttgattc cgtattttct tcattttatc atatttttca gaaaattcat
     3781 caaaaacttg ccaaattgtc agaattatga gaaaatagag gatatttatc acgtggaggg
     3841 actgctatga gagacgatat caaaatcaat gaccgtgctt tggccttgca agaccaaatt
     3901 atcgaaaaac tagagaaagt ttttgataca gatgtggaat tggatgttta caatctaggt
     3961 ctgatttatg aaatcaatct ggatgaaacg gggctctgca agattgtcat gaccttcacc
     4021 gatactgcct gtgattgcgc cgaaagcctg cctattgaaa tcgtggcagg tttgaaacaa
     4081 atcgagggta tcaaggatat caaggttgaa gttacctggt cgcctgcctg gaaaatcaca
     4141 cgaatcagtc gctatggccg tattgccctt ggactaccac ctcgttaagc aggtcaatca
     4201 cttttaaaga tgaaaaaagc aagccgaaaa tggcttgctt tttgatactc aatgaaaatc
     4261 aaagggcaaa ctagaaaact agccgcaggt tgctcaaaac actgttttga ggttgtagat
     4321 agaactgacg aagtcagtaa ccatacctac ggcaaggcga cgttgacgtg atttgaagag
     4381 attttcgagt atgagtttat tttttacctg acttgtccat attccagaag tctgtcacgg
     4441 ctccgcgtga agcagatgat acgatgtggg catatttacc gagtacacca cggctgtaaa
     4501 gtggtggcaa ggttgcttct gccttgcgtt tttcaagttc ttcttcggat acggccatgg
     4561 aaatttcttt ggtatcttgg tcaaccgtaa cgatatcgcc ggtacggaga taggcaattg
     4621 gtccaccatc ctgagcttca ggagcgatat gtccaacaac cagaccataa gtaccaccag
     4681 agaaacgtcc gtccgtcaag agggccacct tatctccctg acctttacca acaatcattg
     4741 aagaaagtga tagcatctca ggcataccag gaccaccttt aggtccaaca aaacgaacaa
     4801 cgactacatc gccatcaacg atttcatctg tcagaacggc ctgaatcgca tcttcttctg
     4861 agtcaaagac cttagctggc ccaacgtgac gacgcacttt aacacctgat accttggcaa
     4921 ctgcaccgtc aggagcaagg ttcccgttca agatgataag cggaccatcc gcacgttttg
     4981 gattttcaag tggcatgata actttttggc ctggagtcaa gtctgcaaag tcagccaagt
     5041 tttcagctac agtcttacca gtacatgtga tgcgatctcc gtgaaggaaa ccatttgcca
     5101 acaagtactt cataaccgca gggacaccac cgacttcgta gaggtcttgg aagacatact
     5161 gaccagatgg tttcaagtcg gccaagtgag gcacacgttc ttgaatcgta ttgaagtcct
     5221 caagtgacaa gtcaacattt gcggcatggg caatggcgag caagtgaaga gtggcgtttg
     5281 tagaaccacc gagagccatc gttacagtaa tagcatcttc aaaggcttca cgagtcaaga
     5341 tatctgatgg tttgagacca agttccaaca tcttaacaac agcacgtcct gctgcttcga
     5401 tatcttcttt cttatcagct gattcagctg ggtgagagga tgaccctggc aaactcatcc
     5461 ctagaacttc gatagcagtt gccatggtat tagcagtata cataccacca caaccaccag
     5521 ggccagggca ggcattacat tcaagacgtt tcacgtcctc agctgtcatg tcaccgtggt
     5581 tccattttcc gataccttca aagacagaaa ccaagtcgat atctttacca tcaagatttc
     5641 ccggtgcaat agttccacca taggcgaaaa tagctgggat atccatatta gcaatagcaa
     5701 tcatagatcc aggcatgttc ttgtcacagc caccgatagc gacgaaggca tccacgttgt
     5761 gaccactcat agccgcctcg atggagtccg cgatgatgtc acgagatgtt agagagaaac
     5821 gcataccagg cgttcccata gcgatcccgt ccgctacggt aatggttcca aactgtacag
     5881 gccaagcgcc tgcagatttg acaccttctt tagccagttt cccgaaatca tgcaagtgaa
     5941 tgttacatgg tgtattttcc gcccaagtcg aaatcactcc cacaatcgat gtttcaaagt
     6001 ccttatctgt cataccagtc gcacgaagca tagcacggtt aggtgattta accatgctgt
     6061 catagatgct actgcggtga cgtttatcta attcagtcat cttatccctc ccatttcagt
     6121 ttttactatt atagcacaat ttaaaggcaa tgaacagaat aaaattcttg aattttcaga
     6181 aaattctata cgcatgtgaa atatttaaaa ttaaaaacaa caaagcggat tagtgcactt
     6241 tctgatgacc agaatatgct ttttaatccg ctttctttaa ataacgtact gtaattttta
     6301 cagaaattct ttcagataag tgtatttaac atctatcttg cattataaat ttctagaacc
     6361 ttctctttta tattcgattc actcaaacca tactcattaa gaagataatc cattttccct
     6421 acttgaccaa atctttcttg aacacccatc cgatgaattt ttgttattcc atcatcagag
     6481 aataattcac ataaagcact gccaattcca cctatctgat tgtggttttc tacagtaaat
     6541 atagtttttc cacttaacat tgtttttatc tgttctggta tcggtttgat tctaaataaa
     6601 tctatcacac ctactgaata acctaattta gacagttcat ctgcaactcg aatacttgga
     6661 gcaaccatta taccagaagc aacgattaca agatcttcac catgccttaa ctcaatgtag
     6721 cctttagaaa aatcttctcc accttgatac acaggaactg gagcttttct aattgttcga
     6781 atatatttta gtccttttaa gtctaatgtc tggttcaata tttcacgaaa ttggatatca
     6841 tcagttgctt caaaaatgat cgatttagga attaaacgta acaatccaat ttcttcaaat
     6901 ggcatatgtg tcccaccatt catttctgca gttactcctg catctgatcc aatcacagtg
     6961 gcatccaatt gtgcgtatcc aagagaaata aataattgat caaatactct tcgtgaagaa
     7021 aaaggaccaa atgtatgaag ataaggtcta aacccctgaa tagacaagcc tgctgcaagg
     7081 ccgaccattt ctgcttccat aatcccaaca ttcacataac ggtctccaaa gtccttttca
     7141 agattatgag tagccatcga acttgacaga tcggcttcta agactactat atcagaatca
     7201 ctttgattag cctctaaaag gaagtctcta tatacatgcc gtaattcttt cgtacttctc
     7261 atcattctgt ttcctccaat tcctgactta atctttctac aactgaagtt aacatttgtc
     7321 tctcctctac agtagggcga agatgatgat tggatttcat ttcttccagc tcttgaaccc
     7381 cttgaccttt aatagtatct aatacaatgc acttaggtga tgaattattt gactgtttta
     7441 attggacaat cccttcataa atttctctaa tatctgaacc cttgacccta atggattcaa
     7501 atccaaatgc tgaaaatttt tctacgaaat cacctggatt acaaatatcc tttgtaaaac
     7561 catctaattg ttttttgttg tcatcaacaa atacaattaa gttggataac tgttgatgag
     7621 aagcaaactg tatagcctcc caacattgtc cctcatttaa ctcaccatct ccaacaatag
     7681 cataagtata aaagggactc tttcttattc tctgaccata tgcaagtcca gttgcaacac
     7741 taattccttg tcctaaagag cccgttgtca tatctatgcc tggcgttaga tttctatcag
     7801 gatgagacgg taatttggtt ccatttgtat ttaaagaata taagaattct ttgtcaaaga
     7861 aaccattcaa atagagtgta ctgtatagag ctggtcctcc atgacctttt gataatatga
     7921 aataatctct atctcgtgct gcaaatattt ctggagtcat tggcattatt tcaccataaa
     7981 gcactgctaa aacttctacg atagacagac ttcctccgta atgtccgaat ccaagatgat
     8041 tcaatgttct aagagtattt aatcggatgt tagtcgcaaa ttttcttaac tcatcttctc
     8101 tattttcact taaaatcatc ccttactcct cctttgcaga tggcttttta ataaaggata
     8161 ctccaaacat aactgctaga ataagaacaa gaccaatcac aatgcctgct tgtgaaccaa
     8221 attgatttaa cattcctaaa ataattcctg atagaccaaa atctgcatct gagaaagttg
     8281 atccttggaa accaagtcct cccaaaactg gcattaaaaa gactggaaga aaactgatta
     8341 aaataccttg taaaaatgct ccaatagtgg ctccacgaac accaccagat gcattcccaa
     8401 tgacacctgc agtcgctcca cagaagaaat gaggcacaac gcctggtaag ataacaaccg
     8461 ttcctgaagc aatcataatt gccatactta ctaaaccacc aataaaacta gagataaatc
     8521 caattagaac tgcattgggt gcataagtat aaacaatcgg acaatccaaa gcaggttttg
     8581 aattaggtac aagacgctct gaaatacctt taaaggctgg aacaatttca cccaaaataa
     8641 ggcgaacacc tgctaaaata acaaataccc ctgctgcaaa ttgacctgct aattgtaaag
     8701 cataaactag accacttgta ccactactga tttctttttc tatatattct gaccctgcaa
     8761 agatagctac aataatgtaa ataactgcca tggataaagt aatactaaca gtgctatcac
     8821 gtaaaaaagc taaactcttt ggaaatttaa tgtcctctgt tgattttgat ttgtcaccga
     8881 taaggctacc agtaaaacca ctcaaccaat atcccaaaga actgaaatga cctaaagcca
     8941 ccttgtcatt tccagttaat tgaaccatat atttttgcac aaatgctggg gaaatactca
     9001 taataatacc gagtgctaat cctcctagta agataagagg caagctagta aagccagcaa
     9061 ctgataaaat gaccgcaatc atacacgcca tatatagagt gtggtgccct gttaaaaaga
     9121 tatatttaaa tcgagtaaaa cgagcgatta agatattgaa caccattcct gcaaacataa
     9181 tcattgcagt agctgagcca tatgttgtta aagctacagc tacaattgct tcattattcg
     9241 gcacaacgcc agataaatga aaagcatgct caaacatggt accaaatgga tttaaagaat
     9301 tttgtacaat tcctgcacca ccagatacaa ctaagaaacc aacaaaggtc ttaattccac
     9361 ctttaataat atcaggtaat ttcttcttct gaagaactaa tcctaaaatt gcaattaaag
     9421 ctactaaaat agctggtgta ctaacaatat ccaatatgaa cttcatcatg acgctagcct
     9481 cctatataag tcctttttct tcacaaagtt tagtaattaa ttctcgtagt tcatccatat
     9541 caataatact atttaagata cgaacatctc caagatgact agctgaatca gctagatcac
     9601 gaccaacaat ccaaatatca gctgcatttg gatctgctcc acctaaatca taatgttcaa
     9661 cttctacatc cgaaacattc aaatcactca atacagattc aatattcatc tgtaccataa
     9721 aacttgaacc taatcctgaa ccacaagctg taccaatttt taacattatc taatcctcct
     9781 gtttaattat cattttaata tcatcatagt tttttgatga tattaaagtt tgaacatgat
     9841 ttttatctct taaaattgtt gttaaatgtg acaaagcctt taaatgactc tcattatcaa
     9901 tggctgcaat acaaatcaac aatcttacct cttgttctgg attatccaat aaataaatcg
     9961 gttcttccaa aactaacatt gacattccta tttcattcac accttcatct ggccgagcgt
    10021 gaggaattgc tactcccttc cctaaattaa taaaaggtcc aaactcttct actttttgaa
    10081 tcattgcctc agggtagttc tccgttatct tatcttgatc caaaagcggt ttagctgcta
    10141 aacgaatcgc ctccttccat cctaattttt gcgaactaac ctgataggtt tctttggtaa
    10201 taagttgttc tagcactggt acaatttcct ttctatcatt tttttgataa agataattct
    10261 ttaacgccaa tcttaattcc aattcttgtg taataattcc atatcttttg acaatattca
    10321 ggatttgttc aatctcaaaa tctccatact ctaaattcgg aaaatctttt aacactagtt
    10381 ctactagttg tattgcttgc tcttcagtca tcataaccga aactagataa tttggctttt
    10441 ctgtctccac ctttatggta gaaaaaacca tatcatagtc actactagct ttcacctgta
    10501 aatcatcaat ctttgaggtt cctataaact caatttgagg aaataatgct aatagattct
    10561 cttttaacat caatgaagaa ctaacaccat taggacaaat gattgctgct ttataccatt
    10621 tttgaggcaa agtatctgct ttctttaaat aacctccgaa atggataaca aaatatgctg
    10681 tttcactatc aggtatggga ttgtcaatag cgtccatcaa gggcatcaaa gaatctttga
    10741 ctaattcaaa taaatcagga taatgttctt taacatgcaa tacatattca tttgaactag
    10801 gtaggccgaa ctttaatcta tagtaagccg gtataaggtg gcggcgaaga ttttctctca
    10861 atccttccct ttgtttaaaa tgtaacaaag aaatatcttc cattctactt ataatagcct
    10921 ctgttaattg attaaagtaa accggagcaa catctacttc accttcaaag caacttgata
    10981 ataaaactgt gatatagcga taatcatcct cagaaaacac cgtatctata attcccaaat
    11041 caaccactgt atccaataaa atagtggtta tatcttgaat aacaggagat actaatgtct
    11101 ctgaaagaca tactctttca acatcccttt gatacctaca cagaatgaat actaaaccga
    11161 aaaggtaaac ttttaattga ttaacaatag gtactagctg tagcttctca taataatctt
    11221 taactacctg atttatcaaa tcataagtta atgaataccc ccaactggat aaaacataat
    11281 ccaaacccca aatccctatg gaggattcca gcaactcact aaccatttga aaagctaagc
    11341 ggtgcttatt ccactctgaa ccgtgtaaag tataaccttt tgctctactg taccctagct
    11401 ccaaatcatt atctaacata atctttctta atgattgaat atcagataag gttgtattct
    11461 tacttacttt caaaaagtct tggtaatgat tattcgatat aaaatctaat cggcaaaaag
    11521 tgtaaagata gattaaagct aagcgagtcg actttggtaa aaccaattca tccgacttaa
    11581 taatatctgt caaagactgc ttcgtacgat ttgataaact atagcgacct tgttttttat
    11641 ccagcactat ccctttatta gctagataag gcactaaata atctattcct tctttgactt
    11701 cctttatagg taagctcacc ttaacagata attcatataa tgatagctca caatgatcca
    11761 tcaaagtcat caaaataact agtgctctat aatcaaacat ttctcttcct ttctaactac
    11821 aattatagtg taaaaattat aagaataaaa gagtatttga gcacaatata atctcacctt
    11881 ttaaaagaaa ttattgggct gaaagttttt agtgattatt ttcaactttc tattgacttt
    11941 taaaaacaaa gtgatatcat ttagatatca aataatggga ggtcattctt atgactgaaa
    12001 aactaatcaa ttcaaaacca aatggtgtat tcgcattgat tctcattgag ttgacaatca
    12061 tacttggtat ctttatattt ataatgggtg ttggttcgga aaacattttt ggaattatta
    12121 tcggaccttt actaatcgta attgcaggtc tagctcatgc tggtttaaaa gttgtcaaac
    12181 ctcaggaagc tctggttctg acactctttg gtaattatac aggtaccatc aaagaacctg
    12241 gtttttactt tgtcaatccc ttcagcgtag cagtcaaccc tgcaaaccac actcgacttg
    12301 gacaaagtgg tgatgttagc acaaaatctc cttttttagg agctaaatca tcaaatgaca
    12361 atgatgtaaa tcttgaaatt ggcaagaaac acatttccct caaagtcatg accttgagca
    12421 attctcgtca aaaaatcaat gattgcttag gaaaccctgt agaaatcggt atcgcggtaa
    12481 cttggagagt tgtcgatacc gctaaggcag tcttcaacgt tgataactac aaagaatatc
    12541 tttcattgca atgtgatagc gccctccgta atattgtccg catctatcct tacgatgtgt
    12601 ctcctaatgt ggatactacg ggtgacgggc aagcagatga aggtagtctc cgtggctcta
    12661 gcgaaattgt tgctaaccgt attcgtgaag aaatccaaag tcgtgttgag gatgctggct
    12721 tggaaatcct tgaagcacgt atcacttacc tagcttatgc tccagaaatt gctgccgtta
    12781 tgcttcaacg ccaacaagca tctgccatta ttgatgcacg gaagatgatt gtagatggtg
    12841 ctgtaggaat ggttgaaatg gcactagaac ggctcaatga aggggaattg gtagaacttg
    12901 acgaagaacg aaaagctgcc atggtttcaa atctccttgt cgttctttgt ggcaatcatg
    12961 atgcacaacc aattgtcaac acaggaagtc tttactaaag atggctgaag ctaaaaaaaa
    13021 gcagatcccc cttcgactct caacaaagtt atacgctgca ctcgcatcat gggcagaaga
    13081 cgactttcgt tcagtcaatg ggcaaatcga atatctcctc acagagtgtg tcaagcaacg
    13141 gaaaaaagac ggaaaatacg tatcagaaac cattgacgaa ccatttgaga ttgatattta
    13201 acatcttctc ctgtctgaca agtcggacag gagaattttt tcatcttttt ttgtcaagta
    13261 actttacttt acaaaaaaaa tgtgttatcc tagtatggtt gatgaaaatc agtagattga
    13321 atcgaatata aatacctaaa ggagaaatca aaatggcagt acctgcacgt cgcacttcaa
    13381 aagcgaagaa aaacaaacgt cgtacacact acaaagtaac agctccatct gtaaactttg
    13441 acgaaactac tggagattac tcacgttctc accgtgtatc acttaaagga tactacaaag
    13501 gacgtaaaat cgctaaagct gcatcagctg aataatagaa gggagatacc atgcgcgtaa
    13561 atattacact tgaacacaaa gaatctggtg aacgcttgta ccttacttct aaaaacaaac
    13621 gtaacactcc agaccgcctt caattgaaga aatactcacc aaaacttcgc aaacacgttg
    13681 tgtttacaga agtgaagtaa gcattcaata cgaatcaata cagaagaaaa acgcttgatc
    13741 agcgtttttt ctttttgtta atttcactat attgcaaggg aaatcattcg aatgactacc
    13801 tttttcacta ccttttttga aataagaata cggattcgga cgattaaaag taagagaaac
    13861 tcaaatgtaa gttggggttc cttttttgta tatttttcaa ataacgcctc tacactattt
    13921 gtagcaaatt caccaactac agttgtatct tagttaaaat aagttagaat atgtaagtga
    13981 gtaccagata taccaagaca tcgtcaccat ctaaggtata ttcaaaatac aaaagttgac
    14041 caactagatt tctgaatatc cttatatatc cattcttaaa attggtttaa atagcgtagt
    14101 cttttaaact agttttgaga atccaaaaaa tcttcctaca tatgtaagaa gattttttag
    14161 ttcagaatga ttagatttag ctaatggata cctatcctac ccactcaccg ttagcattga
    14221 ctcgatagcc atcgggtgta gtcgtgttta ctaataaatc tcctgaatta taggtatagt
    14281 accatttacc agaaactgta a
//
LOCUS       DAVLCS010000048        14094 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLCS010000048 DAVLCS010000000
VERSION     DAVLCS010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14094
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.048"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            83..880
                     /locus_tag="VXC78_001779"
     CDS             83..880
                     /locus_tag="VXC78_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV0583804.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="VXC78_001780"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="VXC78_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2383..3657
                     /locus_tag="VXC78_001781"
     CDS             2383..3657
                     /locus_tag="VXC78_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV0583805.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEHYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VXC78_001782"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VXC78_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV0583806.1"
                     /translation="MNGIINLKKEAGITSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4806..5108
                     /locus_tag="VXC78_001783"
     CDS             4806..5108
                     /locus_tag="VXC78_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0583807.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5216..5854
                     /gene="udk"
                     /locus_tag="VXC78_001784"
     CDS             5216..5854
                     /gene="udk"
                     /locus_tag="VXC78_001784"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV0583808.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5982..7322
                     /locus_tag="VXC78_001785"
     CDS             5982..7322
                     /locus_tag="VXC78_001785"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV0583809.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7300..7512
                     /locus_tag="VXC78_001786"
     CDS             7300..7512
                     /locus_tag="VXC78_001786"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV0583810.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7509..8384
                     /locus_tag="VXC78_001787"
     CDS             7509..8384
                     /locus_tag="VXC78_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV0583811.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQIIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8377..9192
                     /locus_tag="VXC78_001788"
     CDS             8377..9192
                     /locus_tag="VXC78_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV0583812.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQIFAEIKEAVERAHSQFKNE"
     gene            9185..9616
                     /locus_tag="VXC78_001789"
     CDS             9185..9616
                     /locus_tag="VXC78_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0583813.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9623..11290
                     /gene="recN"
                     /locus_tag="VXC78_001790"
     CDS             9623..11290
                     /gene="recN"
                     /locus_tag="VXC78_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV0583814.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKERIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11292..12020
                     /locus_tag="VXC78_001791"
     CDS             11292..12020
                     /locus_tag="VXC78_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV0583815.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12099..13922
                     /gene="lepA"
                     /locus_tag="VXC78_001792"
     CDS             12099..13922
                     /gene="lepA"
                     /locus_tag="VXC78_001792"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV0583816.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         4174 a         2566 c         3351 g         4003 t
ORIGIN      
        1 acttttatga aatatagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat aatatggagg
     1021 tcaccttatg actcgtgatt ttaaatttga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg agcatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac cccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaaca ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggacggctt cagggaaatt ccctcaattt gttgacgaga gtccaagctg
     1741 ccacaatttg agctatactc atgatgtggg tgcagcagcc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttattat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggtcatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgttaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattgc agagtcaaat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggccttattg gctaaggaca aggaagtaca ggccttggaa
     2701 aaccagttgg cgaccttgcg tttggagcat gaaaatcaat tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgcaatca ggtcaaaaat cagctcctac tgcaagaaaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt caaagctcaa caatccacaa aagccatcgg ggaaagtttg
     2941 gaacactatg cggaaagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaataacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt aatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgctcgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gatgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataata attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct attaggtact
     4681 caaataatct atatagaaat ttagaggtgt gaaatgaagc aatttaaaat tctttcagat
     4741 aaatatttag agtccattac aggttctggt gggaacttag gcccaggatt tggtgtgata
     4801 attccatgat gcgaaatgag tttcgagaaa gggtggagca acttcttcaa caaaaagaaa
     4861 taaatgaaaa tagtgagttg agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa
     4921 atgaaaaata ccaaacggtc atggccaatt tgagtcaagg gttgtcactt tacctcatga
     4981 cgcatcatta ccaggcacct aagtctgtca ttgattttgg tttatggatt gccaaagctc
     5041 ctagccagga aagagggaga ctggctttct tgcagatgct tgctcaaacc ctacagggct
     5101 ttcgttaaaa ctgtcgaaca tcagagggaa gactctggtg ttttttgctg atgagactat
     5161 aaattttgta aaaaatgtga tagaatagac gacggataaa ataacggagg atagcatgca
     5221 aaatagacca atcattattg gagtgacagg tggttctggt ggtggtaaaa ctagtgtttc
     5281 aagagccatt ttatcgcatt ttcctgatga aaagatttcc atgattgagc atgattcata
     5341 ctacaaggat cagtctcatt tgacctttga agagcgtgtc aaaaccaact atgaccatcc
     5401 ttttgccttt gatacagact tgatgatcga gcagattaag gaattgttgg cagggcgtcc
     5461 ggtggacatc ccgacctacg actatacaga gcatacacgg agtagcaaga cctatcgtca
     5521 ggagcctcaa gatgtcttta tcgttgaggg cattttggtc ttggaggaca agcgtctgcg
     5581 cgatttgatg gatatcaaga tttttgtgga tacggatgac gatgtgcgca ttattcgtcg
     5641 tatcaagcgt gatatggagg agcgtggccg tagccttgat agcgttatta accagtactt
     5701 aggtgtggtc aaaccaatgt accaccagtt tatcgagtca actaagcgtt atgctgatat
     5761 cgtcattcct gaaggggtta gcaataccgt ggctatcgac ctgttgacga ccaagattgc
     5821 aaagattttg gaagaagctc gaaacagcaa ataatcacat gtggaggcct tgcctccttt
     5881 ttctattttt ccctcataat ggtacataaa tggagatttt taggcatatt tttggtataa
     5941 taatacccat gaaagagcaa gtaaatgaat agtaggtgga gatggaaaag tatttatcgg
     6001 taacaacttt gaccaagtat ctgaaaatga aattcgataa agacccatac ttggaacggg
     6061 tctatttaac tggtcaagtt tccaactttc gtaaacgacc tactcaccaa tatttctccc
     6121 taaaggatga ccatgcagtt attcaagcga ccatctggtc tgggatttat cagaaattag
     6181 ggtttgacct ggaagaagga atgaagatca atgtgattgg gcgtgtacag gtctatgaac
     6241 caagtggtag ctactccatc atcattgaaa aagctgagcc tgatggggtt ggggcgcttg
     6301 cgattcagtt tgaacaactt aagaaaaaat tgacagaaga aggcctgttt caagaacgct
     6361 tcaagcaagc tctaccccaa ttttctaaga gaattggggt agtaaccagc cgtagtggag
     6421 ccgttattcg agatattatc acgaccgtca gcaggcgatt cccaggtgtt gacatccttc
     6481 tttatcctac caaggttcaa ggtgaagggg ctgcggagga aattgctaga aatattgcgc
     6541 gtgctaatca acgggacgat ttggatttgc tcattattgg tcgtggaggt ggttctattg
     6601 aggatctctg ggcctttaac gaagaaattg tggtacgagc tatttttgaa tctcgtttgc
     6661 cagttatctc tagtgtgggg catgagacgg atgtgacctt ggcagatttt gtggcagatc
     6721 gacgcgctgc aacgccaaca gcggcggctg aactggcaac acctgtgacc aagttggatg
     6781 tattaactca tttgcaaaat caggaaaaac ggatggcaac ggcagtccga aatgttctat
     6841 ctaagaaaca agaggctttg aaaaaatgca gtcagtctgt tatctttaga caacctgagc
     6901 gcttgtatga cggttatttg caacgcttgg accaactgca actgcgtttg aaacaaagtt
     6961 tgcgaactcg gatttctgat aacaaacaat tagttcaagc aagaactcat caattagtac
     7021 aattatcacc tgttaccaaa atccaacgct atcaagaccg tttaggacag ttggacaagc
     7081 tcttaggtag ccaaatggcg ttagtttatg acgccaaggt tgctgaggcc aagcgacttt
     7141 cggaagcttt gctcatgttg gatactagcc gaatcgtggc gcgtggttat gctattgtca
     7201 aaaaagaaga gtccattgta gattcggttg agagtttgaa gaaaaaagac caagtaacgc
     7261 ttttgatgcg agatggtcaa gtagaattag aggttaaaga tgtcaaaaca aaagaaattt
     7321 gaggaaaatc tagcagaact ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct
     7381 ctggaagatg cgattactgc ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct
     7441 acgctggaca aggctgaaaa gaccttggtc aaggtcatgc aagaagacgg aacagaaagt
     7501 gattttgaat gaaaaagcaa gaaaaattag ctcttgtcga gtcggctttg gaagattttt
     7561 atggagacca gcagtttgcc tctagtttac gggagtctgt tctctattct attcatgctg
     7621 gtggcaagcg tattcggcct tttctcttgt tagaagttct ggaagccttg caggttacca
     7681 tcaaacctgc tcacgcgcag gtagctactg ccttggagat gattcataca gggagcttga
     7741 ttcacgatga ccttcctgct atggatgatg acgattatcg aagagggcgg ttaaccaatc
     7801 acaagaaatt cggtgaagct atggccattt tggctggaga tgccttattc ttagacccat
     7861 atgccttgat tgcgcaggca gatttgccaa gtcagattaa ggtggacttg attgccaact
     7921 tatcccttgc ttcaggtagt ctgggtatgg tggcagggca agttttggat atggagggcg
     7981 aacaccagca cttgtctttg gaagaacttc agattattca tgccaataag actgggaagt
     8041 tactagccta tcccttccaa gcggcagcta ttatagctga attgtcacct gaaatgcagg
     8101 tgaagctgaa aactgtgggt gaattgattg gacttgcttt tcaagtcaga gatgatgtac
     8161 tggatgtgac agctagtttt gaggaaatcg gcaagacacc tcaaaaggat ctgcaggcag
     8221 aaaaatcaac ctatcctgcc ctgttgggct tggaagagtc cattgccttt tgtaaccaaa
     8281 ccctggatca agctaatgaa aaattagaag aaattgccca gcagcttccc tttgaaacag
     8341 aatcgattgt aagtgtagta gaaagtttga gaatcaatgg ctaaggaaag agtggatgta
     8401 ctagcttata aacaggggtt gtttgaaacg agagagcagg ccaagcgagg tgtaatggct
     8461 ggcctagtcg tagcagtcct taatggagaa cggtttgaca agccaggaga gaaaattcca
     8521 gatgacaccg aattaaaact caagggagag aaactcaagt atgtcagccg tggtggtttg
     8581 aaactggaaa aggccttgca ggtctttgat ttgtcggtgg atggcgcgac tacgattgat
     8641 atcggggcct ctactggagg ttttaccgat gtcatgctac agaatagtgc caagttggtc
     8701 tttgcagtcg atgttggtac caatcagttg gcttggaaat tacgccaaga cccacgagtt
     8761 gttagcatgg agcagttcaa tttccgctat gctgaaaaga ctgatttcga gcaggagccg
     8821 agctttgcca gtattgatgt gagtttcatt tcccttagtc tgattttgcc agccttgcat
     8881 cgtgtcttgg ctgatcaagg tcaggtggta gcacttgtca aacctcagtt tgaggcagga
     8941 cgtgagcaga ttgggaaaaa tggaattatt cgagatgcta agattcatca gaatgtcctt
     9001 gaatctgtaa cagctatggc agtagaggca ggtttttcag tccttggctt ggacttttct
     9061 cccatccaag gtggacatgg aaatattgaa tttttagcgt atttgaaaaa agaaaagtca
     9121 gcaagcaatc agatttttgc tgagattaaa gaagcagtag agagggcgca tagtcaattt
     9181 aaaaatgaat aaaaaagaga gacttgaaaa aattagaaga ttggtgacag attatcaaat
     9241 cggcacgcaa gaagaaattg tagaacattt gaaagaagca ggtatcactg ccactcaggc
     9301 gacggtatcc cgagatatca aagagttagg tattgtcaaa attcctttga gagacaacac
     9361 ctatgtctac gaattaccaa aatcaatcgt aaaaagtctg caactggctg aagacaatat
     9421 cgaatcggct gaattgatgg ataagatgat caatctccaa gttattccag gaaatacggc
     9481 ttttgtaaaa gctcagttaa tcgatacttt tgcagacaag atttttagtt gtttgactga
     9541 tgatagctcg attttagtca ttgccagaag tggaagtcta gcagaggaaa tctttgaaca
     9601 agtaaaaaat tggtaggtct atatgttact tgaaatttcg ataaaaaact ttgccattat
     9661 tgaggctatt tccctcaatt ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc
     9721 agggaagtcg attatcattg atgccatgaa tatgatgttg ggagctcgtg cgacgacaga
     9781 tgttattcgt catggtgcac caaaggcaga gattgagggg cttttctcag ttgagaatag
     9841 tcgtctttta caggaaattt ttgatgagca aggtttagaa ttaggtgatg aaattatcat
     9901 ccgtcgggaa atcttgcaaa atggtcgtag tatcagccgt gtaaatggtc agatggttaa
     9961 tctgtctgtt ttgcgagcta ttgggcaaca tcttgtagat attcatggtc agcatgacca
    10021 tgaggagtta atgcgtcccc aactgcatat ccagatgttg gatgaatttg gtgatgccgc
    10081 tttttgggac ttgaaagaaa cctatcaaac gagttttgat gcctatcgga aaatgcgcaa
    10141 gcaggttctg gaagtcaaga aaaaccaaca ggaacacaag gaacgtatcg aaatgttgga
    10201 atttcaaatg gcagagattg aggcagcaaa cttgcaggct ggagaagact tggctctcaa
    10261 tcaagagcga gataaactcc tcaaccacaa aaatattgcg gatacactga ccaatgccta
    10321 cagtatgttg gacaatgaag atttttcaag tctggccaat gttcgttcag ctatgaatga
    10381 catggaaagt gtcgaagagt atgatcctga ataccgtgaa atttcaagct ctctgtctga
    10441 gacctactat gttttagaag acattagcaa acgtttggaa gctatcattg aggaccttga
    10501 ttttgatggc aatcgcctga tgcaggttga gaatcgtttg gacctccttc atactattac
    10561 tcgtaagtat ggtgggactg ttgatgatgt tttgctttat tttgccaaga ttacggaaga
    10621 atacaatctc ttgacaggca ataatctttc gtctgaggac atggaagcag agcttaagaa
    10681 gttggaagtc aatcttgtca atttggcagg tcaacttgct tctgctcgtc ataatttggc
    10741 tcagcaactc gaagctgaga ttaaacaaga actgcaagat ctttatatgg aaaaagccca
    10801 gtttcaggtt cattttagta agggaaaatt cagtcgtggg ggaaatgaaa tggttgagtt
    10861 ttatatttca accaaccctg gagaagactt taaacccttg gttaaggttg cttctggagg
    10921 ggaattatct cgtctcatgt tagccattaa gtctgccttt tcacgtaaag aaggcaagac
    10981 tagcattgtc tttgatgagg tggatacggg agtttcaggt cgtgttgctc aagctattgc
    11041 tcagaaaatt cataaaattg gtcagcatgg tcaggttttg gctatctccc atttgccaca
    11101 agtaattgcg attgcagatt atcaattctt tattgagaag attagtaatg accattcaac
    11161 ggtttcgact gttcgtctct tgacagtcga agagcgagtg gaggaagttg ccaagatgtt
    11221 ggcaggtgat gatgtgacag aagcagccct gacgcaagcc agagaattgt tgagaaacag
    11281 ggagaaataa gatgacagat tattatgtaa ttggagatgt tcacggaaaa gctgggatgc
    11341 tggaagacct tcttaaaacc tgggatggtc agacccagtt gctctttcta ggtgatttga
    11401 ttgacagagg tgaggatagt caccgtgttc ttgaaatggt caaggacttg gtggacaatc
    11461 aaggggctat ctgtttgtct ggaaaccacg agtatatgtt tttgacttgg ctagatgacc
    11521 cagaagaaag ttatgaccat tatcgtcgca atggtggaga tacaaccatt aactctatcc
    11581 taggtcgtcc cttggatgca ccagttgatg gagtagaaga tgccaagcgg gttgccgctg
    11641 aagcgtcaga cttggtcgaa ttcattcgtc aaatgccatt tgtagtagag acagacaagt
    11701 atatatttgt tcacgcaggt attgatttga ctttggacga ctggcatgaa acaacagatt
    11761 ataaaaaagt atggcttaga aaaccattcc acggagctga aaatcatact ggaaaaacca
    11821 ttgtcttcgg tcatacaccg gtctatggtt tgttacagca agaacgcggt acatctgagc
    11881 tttggactac agaagatggc aagattggaa tggatggagg agctgtttat ggtggtgtcc
    11941 ttcacgggat tgtctttaca gaccaaggaa tgacagaaca ccactttatc gaaaatgacg
    12001 gctttgtcgc tgaagattag tactcctagc agggtatggt cttgtcaaaa tatcaaaaac
    12061 aatttataat aaatagatac cctgaaagga agagaatcat gaacttagaa gaattgaaaa
    12121 aacgacaggg gaagatccgt aacttctcta ttatcgccca tattgaccac gggaaatcaa
    12181 ctctagcaga ccgcattttg gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc
    12241 agcttttgga tagcatggat ctagagcggg aacgtggaat tactattaag ttgaatgcca
    12301 tcgagttgaa ttacactgca aaagatgggg aaacttatat tttccacttg attgacacac
    12361 cagggcacgt tgactttacc tatgaagttt cacgttcgct agctgcctgt gagggtgcta
    12421 ttttggtggt cgatgcggct caaggaattg aggctcaaac tcttgccaac gtttatctgg
    12481 ctttggataa tgatttggaa atcatgccta tcattaataa aattgacctg ccggctgcag
    12541 atccggagag cgtgcgtaca gagattgaag atgtgattgg tttggatgcc agtgaagcag
    12601 ttttggcttc tgccaaggct ggtattggga ttgaagaaat cctcgagcaa attgtagaaa
    12661 aagtaccagc accaacgggt gatgtgacgg cgccacttaa ggccttgatt ttcgactctg
    12721 tttacgatgc ttaccgtggg gttatcctcc aagtgcgtgt catggacgga gtggtcaaac
    12781 ctggtgataa gattcagctc atgagcaata gtaagacctt tgatgtggcc gaagtcggta
    12841 tttttacacc aaaagcggtt ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg
    12901 cggcgtctat caagacggtt caggatactc gtgtgggtga taccgttacc ttggcaacca
    12961 atcctgcggc agaaccatta catggttata agcagatgaa tcctatggtc tttgcgggtc
    13021 tctacccaat cgaatcaaac aagtacaatg acctgcgtga agcgcttgaa aaattgcaac
    13081 tgaatgatgc tagtcttcag tttgaaccag aaacatctca ggcacttgga tttggtttcc
    13141 gttgtggatt tcttggactt ctccatatgg atgttatcca ggaacgttta gagcgtgagt
    13201 tcaatattga tctcatcatg acagctccgt ctgttattta caaagttaat ttgaccgacg
    13261 gtgagtctat ggatgtgtct aacccatctg agtttccaga cccaactaag attgcgacca
    13321 ttgaagagcc ttatgtcaag gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa
    13381 tggagctagc tcagcgtaag cgtggggact ttgtgactat ggactatatt gatgataacc
    13441 gtgtcaatgt tatctatcaa attcctcttg ctgaaatcgt ctttgacttc tttgataaac
    13501 ttaagtcttc gacacgtggt tatgcaagtt ttgactacga attgtcagaa tatcgcccat
    13561 ctaagctagt gaaaatggat atccttctca acggagacaa ggtggatgcc ctcagcttta
    13621 tcgttcataa ggactttgct tatgaacgtg ggaaactcat cgttgataag ctcaagaaaa
    13681 tcatccctcg ccaacaattt gaggttccaa tccaagcggc tattggacac aagattgtcg
    13741 ctcgtactga tatcaaggcc cttcgtaaga acgtacttgc taaatgttat ggtggtgacg
    13801 tttctcgtaa gcgtaaactc cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca
    13861 tcggatcagt tgaagttccg caagaagcct tcctcagcgt cttgagtatg gatgaagaat
    13921 aagttatcag aaatgccttt ccttgttcac aggaaattta tataagaatc aatagtaaag
    13981 caggcttaga tggtctgctt ttttagtttt tatactcttc gaaaatctct tcaaaccacg
    14041 tcagcgtcgc cttaccgtat gtatggttac tgacttcgtc agtttcatct acaa
//
LOCUS       DAVLCS010000049        14039 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLCS010000049 DAVLCS010000000
VERSION     DAVLCS010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14039
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.049"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(17..868)
                     /locus_tag="VXC78_001793"
     CDS             complement(17..868)
                     /locus_tag="VXC78_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0583817.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            1195..1587
                     /locus_tag="VXC78_001794"
     CDS             1195..1587
                     /locus_tag="VXC78_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583818.1"
                     /translation="MKIKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKENEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAVDMARQNWWDLSAAISGSWSPN"
     gene            1609..2400
                     /locus_tag="VXC78_001795"
     CDS             1609..2400
                     /locus_tag="VXC78_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583819.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            2393..3034
                     /locus_tag="VXC78_001796"
     CDS             2393..3034
                     /locus_tag="VXC78_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583820.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            3038..3688
                     /locus_tag="VXC78_001797"
     CDS             3038..3688
                     /locus_tag="VXC78_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0583821.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            3699..3986
                     /locus_tag="VXC78_001798"
     CDS             3699..3986
                     /locus_tag="VXC78_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583822.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            4132..6645
                     /gene="secA"
                     /locus_tag="VXC78_001799"
     CDS             4132..6645
                     /gene="secA"
                     /locus_tag="VXC78_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV0583823.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            6726..7757
                     /locus_tag="VXC78_001800"
     CDS             6726..7757
                     /locus_tag="VXC78_001800"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0583824.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            7759..8790
                     /locus_tag="VXC78_001801"
     CDS             7759..8790
                     /locus_tag="VXC78_001801"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0583825.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            8829..9197
                     /locus_tag="VXC78_001802"
     CDS             8829..9197
                     /locus_tag="VXC78_001802"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV0583826.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            9187..10290
                     /locus_tag="VXC78_001803"
     CDS             9187..10290
                     /locus_tag="VXC78_001803"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV0583827.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            10309..12324
                     /gene="recG"
                     /locus_tag="VXC78_001804"
     CDS             10309..12324
                     /gene="recG"
                     /locus_tag="VXC78_001804"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV0583828.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWCMIALHLEKKEHLD"
     gene            12640..13620
                     /locus_tag="VXC78_001805"
     CDS             12640..13620
                     /locus_tag="VXC78_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV0583829.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT         4133 a         2553 c         3127 g         4226 t
ORIGIN      
        1 tgagagttat tacaaattat aggtttgaaa aatcattaat ttctttttcg agtattttaa
       61 ctaatgcctc ttctttggtt agtcgtaata aagttattcc tttatcaatc aaatcggagt
      121 tatgttgtag tattcccaag cgtacttgag agaatccaag aatatcgtat atttttaatt
      181 cttctgctaa taccaaaagt tgtagggtga ttgtttcaca ttctttgaat aaatgatgtt
      241 gaaaatatac agtggagaga ttggctaaaa aagatgataa aaatgctttt gtttctcgga
      301 agtatttata tttctcgatg gttttcataa ttctatcaat aagaagggga agattttcag
      361 aaggaaagaa aaagagaatg gttccaagca atttcaaatc actaatgtac catgtatcca
      421 taggttcaag atagtcccaa atttcttcat acaaatcttt caagacgtgg ttgtttttga
      481 atcctttagt tcgtaactct gtgacaattt ttgtatgacg atagatattt tgaataggaa
      541 catcgtgatg tgtcttaaga tatttttgac atttctcagt gagttcaacc atttttctag
      601 tatcttgaaa agtagacgga ttttggctct ctacaataat atctcgcctt ttactaggat
      661 ggtattcgtt gcatatatac ttgaattctg ccaagctcat atcaatttgt tcaagaagaa
      721 ataccatgtt ttcaaaactg ggaataactt taccgtgttc aatatttgtt agagttgttc
      781 gatgtatgac ttgtccacat acatcttgtt gggtcaatcc ttttgacttt cgaatttctt
      841 taaaaatttg tccataatcc catctcatat tgttcctcct aggtaaatgt gaatattttc
      901 tacatttata aaaaacgtag aaaaaggtgg tattattata tcaaaaagga gggaaaaagt
      961 catgggcttt aaaaaatatt tgaagaattt accgaaaaac tctggatttt tgatttggag
     1021 ttggattcaa cttatctggt ttgaaacatg gttttgggga taaagaaatt agagtctata
     1081 cataataagt aaaggaggaa tttgtatgat ataccatcgt ttagaataag tctatattta
     1141 aaatagaagt tataaggaat cttcttgaat aaaaaatgaa aggaaacaga aaaaatgaaa
     1201 attaagaaat tattgaaaat ggttattcct gttttaatga taagtgctgt tggaactact
     1261 ttcgtagaag caaatcagat aggtgctttt agtaattttg ttattactac cagttataag
     1321 agaacaggtt atttgactaa agaaaatgaa ggtgcggaat atatcatgaa cttaaatcct
     1381 tgtagaaatt tacatcccat gactgttaag catcgtatag taaattctaa tggagaagct
     1441 cgtagtggag aatcgttaac aacctgtggt actcgttcaa ctcatggtaa ttgggcaacg
     1501 gttggctatg tttatgcagt agatatggca agacaaaatt ggtgggattt atcagctgcc
     1561 atttcaggta gttggtcacc aaattaattc gtaaagtagg tataatttat gaagattcct
     1621 ctcttaactt ttgcaaggca taaatttgtt tatgtcttgc ttactttgct ttttcttgct
     1681 ttggtttatc gtgatgtttt gatgacttat ttcttttttg atattcatgc gcccgatcta
     1741 gctaaattcg atggacaagc aattaaaaat gacttattaa aatcagcatt agattttcgt
     1801 attctccagt tcaatctagg tttttatcaa tcatttatta ttccaatcat cattgttttg
     1861 ctaggttttc aatatattga gctgaaaaat aaagttttac gattgagtat tggaagagaa
     1921 gtgagctatc aagggttaaa aagaaagttg actttgcaag ttgcaagtat cccttgtttg
     1981 atatatttag tgactgtgct gataattgca attataacct atttctttgg gactttttct
     2041 cctcttgaat ggaattctct attttctgat gggagtggtt tacaaagact cctagatgga
     2101 gagataaaaa gctatttgtt ctttacttgt gtcctattaa tcggtatttt catcaatgca
     2161 atctattttt tacaaatagt tgattatgtg gggaatgtga ctcgttcggc aatcacctat
     2221 ttgatgtttc tttggcttgg ttctatgctg ctctatagtg ccttgcctta ctatatggtt
     2281 cctatgacga gtttgatgca agctagctat ggggatgtaa gtttgatgaa actctttact
     2341 ccttatatcc tttatgttgt cccttatatg gtacttaaaa aatatgaaga taatgtttaa
     2401 gaattttaac aatatttggc taaagagaaa gatcgtttta ctacttcgta tagttctgat
     2461 gatgattttg ataaactatc tattgtcaac agcggttcaa aagcaggatg ctgttatctt
     2521 tttcaagaga gaattgattt caattttttc ctataatgac tattctgaag cgaatttaga
     2581 aatccccaaa ctcttgttaa acctttcgct tttcatggta ggatggctct ctgtcatttt
     2641 acttgaaagt gatttggcag accattacca tcacttgatt cgctatcaat caagctcctt
     2701 tttcgattat acaaggaaac gattggttgt catttctaaa ttttttactc aagatttgtt
     2761 tgtctggttt cttggtttac ttccgctagg aattcatttc aaaacagtcg cacttttctt
     2821 tttacttgct cagttaatga tgttgtactt actactgtct tatctgatag cactgattag
     2881 tgcgggcgct ggtttttctt tttttctcta ttttttggca tttgtgggac aagaatggat
     2941 gatggatcat attgtaacag tgtatttagt actcttaagc ttattagtta tgttgattct
     3001 tagtcgcttg gaagagaaat ttaagaaagg ataaacgatg agacttgaaa ttataaatgg
     3061 acagaaaatt tatgggaaaa gacctatttt aaatcagttg aatttggtgt ttcaatcagg
     3121 aaaaatttat ggacttaaag gtgataatgg atctggcaag acggttcttt taaagatact
     3181 tgctggttat attaagcttg acaaaggaaa agttcttcaa gatggtaaag tttacggggt
     3241 aaaaaatcat tatattcagg atgcaggaat tttaattgaa aaagtcgagt ttttatctca
     3301 tttatccctg agagaaaatt tggaactgtt aaggtatttt tcatctaaag ttacggaaaa
     3361 aagaattgcc tattggattc aatactatga tttacaggaa tttgaagacg ttgaataccg
     3421 tcatttatcc ttgggaacaa agcaaaaaat ggccttgatt caagccttta tttcctctcc
     3481 ttctatactc tttctcgatg aacctatgaa tgctttggat gagaaaagtg tgaggttaac
     3541 caaacaggtc attttatctt acctgaaaaa agaaaatggt ctggttatcc tgacgtcgca
     3601 catatcggaa gatatttcag acctttgtac agatgtatta gttgtcgaaa atggacatat
     3661 acaatatgta aaggatatac aatcctagga gatggcttat ggcacatcta aaatcattta
     3721 ttacacgcta ttccaaggtt tatattggtt tagttctgct gatctggctg tctttcttct
     3781 ttatcccttg ggatagagcg attctggggg taaggattga catcttcatc atacagaaag
     3841 tcttgctagt ttttggaatt ctgtccattt tgatggcctt gctgtccaag aaagtcagtc
     3901 tctttgtttt tggactgatt tgctgtcttt ctctttggat taacttattt atcacatttg
     3961 ccattttgcc aatttttggc aattaaacag tcataaaagt cggagaggtt agcttgaaaa
     4021 ctaacctctt tttccttttc aaaatgggga ttcttccttg aaaataatca gtaattgtgc
     4081 taaaattaaa ggaacattct aaaatattcg gaatttaaag taaggaaaaa catggctaat
     4141 attttaaaaa caattatcga aaatgataaa ggagaaatcc gtcgtctgga aaagatggct
     4201 gacaaggttt tcaaatacga agaccaaatg gctgctttga ctgacgacca actaaaagca
     4261 aaaacagttg aatttaagga acgttatcaa aatggagaat cactggattc attgctttac
     4321 gaagcatttg cggttgtccg tgaaggtgcc aaacgtgtcc taggtctctt cccttataag
     4381 gttcaggtca tgggggggat tgttcttcac catggtgacg tgccagagat gcgtacaggg
     4441 gaagggaaaa ccttgactgc gaccatgccg gtatacctca atgccctttc aggtaaaggg
     4501 gttcacgtag ttacggttaa tgaatacctg tcagaacgtg acgcgactga gatgggtgaa
     4561 ttgtactctt ggcttggttt gtcagtaggg attaacttgg ctaccaaatc tccaatggag
     4621 aaaaaagaag cctatgagtg tgatattact tactcaacta actcagaaat cggatttgac
     4681 taccttcgtg acaacatggt cgttcgcgct gaaaacatgg tacaacgtcc gcttaactat
     4741 gccttggtcg atgaggttga ctctatcttg attgacgagg ctcgtacacc tttgattgta
     4801 tcaggtgcca atgcggttga aaccagtcag ttgtatcaca tggcagacca ctatgtaaaa
     4861 tctttgaaca aagatgacta catcatcgat gtgcagtcta agactattgg tttgtctgat
     4921 tcagggattg acagggctga aagctacttc aaacttgaaa acctctatga catcgaaaac
     4981 gtggctttga cccactttat cgataacgcc cttcgtgcca actacatcat gcttctcgat
     5041 attgactatg tggtgagcga agagcaagaa atcttgattg tcgaccaatt tacaggtcgt
     5101 accatggaag gtcgtcgtta ttctgatgga ttgcaccaag ctattgaagc caaagaaggt
     5161 gtgccaatcc aggatgaaac caagacatct gcctcaatca cgtaccaaaa ccttttccgt
     5221 atgtacaaaa aattgtctgg tatgacgggt acaggtaaga ctgaggaaga agaatttcgt
     5281 gaaatctaca acattcgtgt tattccaatc ccaacaaacc gtcctgttca acgtattgac
     5341 cactcagacc ttctttatgc aagtatcgaa tctaagttta aagcggttgt cgaagacgtt
     5401 aaggctcgtt accaaaaggg tcaacctgtc ttggttggta cagtagcggt tgaaactagt
     5461 gactacattt ctaagaaatt ggttgcagct ggtgttcctc acgaagtctt gaatgccaaa
     5521 aaccactata gagaagccca aatcatcatg aatgctggtc aacgtggtgc cgttaccatc
     5581 gcaaccaaca tggcgggtcg tggtaccgac atcaagcttg gtgaaggtgt tcgtgaactt
     5641 ggaggacttt gtgttattgg tacagaacgt catgaaagtc gtcgtatcga taaccagctt
     5701 cgtggacgtt caggtcgtca aggagatcca ggtgagtcac aattctacct atctcttgaa
     5761 gatgatttga tgaaacgttt tggttctgaa cgcttgaagg gaatctttga acgcttgaac
     5821 atgtctgaag aggccattga gtctcgcatg ttgacgcgtc aggttgaagc agctcagaaa
     5881 cgtgtcgaag gaaataacta cgatacccgt aaacaagtcc ttcaatacga cgatgtcatg
     5941 cgtgaacaac gtgagattat ctatactcaa cgttatgatg tcattactgc agaccgtgac
     6001 ttggcacctg aaattcaggc aatgatcaaa cgcacgattg gtcgtgtcgt tgacggtcat
     6061 gcgcgtgcta aacaagatga gaaactagag gcaattttga acttcgctaa gtacaacttg
     6121 cttcctgaag attctattac gatggaagac ttgtcaggct tgtctgataa ggccatcaag
     6181 gaagagcttt tccaacgtgc cttgaaggtt tacgatagtc aggtttcaaa actacgcgat
     6241 gaagaagcag ttaaagaatt ccaaaaagtt ttgattctac gagtggtgga taacaagtgg
     6301 acagatcata tcgatgccct tgatcaattg cgtaacgcgg ttggacttcg tggctatgct
     6361 cagaacaacc ctgttgttga gtatcaggca gaaggtttcc gtatgtttaa tgatatgatt
     6421 ggttcgattg agtttgatgt gacacgcttg atgatgaaag cacaaattca tgaacaagaa
     6481 agaccacagg cagaacgtca tatcagtaca acagcgactc gcaatatcgc tgctcaccaa
     6541 gcaagtatgc cagaagattt ggatttgagc cagattggac gcaatgaact ttgcccatgt
     6601 ggttctggta agaaatttaa aaactgtcac ggtaaaagac aataaaatga gatagtttag
     6661 aggcggatat cttgtgaaaa gtaaattttt actgggtatc cgtttgcttt ataaggagat
     6721 gagttatggt atttacagca aaaagctcta aaataaatat agaagaagtt cgtgccttgt
     6781 caaaattaga aggtcaggct ttggagagga aatcacagcg agatcaagag ctagaagcca
     6841 ttatacgtgg agaagaccag cgaattctct tggtaatcgg gccatgctca tctgacaacg
     6901 aagaagctgt ccttgaatac gctaagcgtt tggcagtcct acaagaagaa gtggcagatc
     6961 gtatctttat ggttatgcgt gtttatactg ccaaaccccg taccaacgga gatggctata
     7021 agggcttgat tcaccagcct aacgcgacag aagcgcctag tcttatcaat ggaatcaaag
     7081 ccgttcgcca tcttcactat cgtgtcatca cagaaacagg gatgacaact gctgatgaaa
     7141 tgctttatcc tgaaaacctt ccgcttgtag atgatttgat ttcttacatg gcagttggtg
     7201 cccgttcagt tgaagaccag caacaccgct ttgtggcaag tggggcagga ttttctactg
     7261 gttttaaaaa tccaacctct ggaaatctca atgtcatgtt taatgggatt tatgctgctc
     7321 aaaacaaaca aagtttcctt ttcttaggaa aagaagtaga aacaactggg aacccgcttt
     7381 cacacgctat tcttcgtggt gctcttaatg agtatggaaa aaatattccc aactactatt
     7441 atgacaattt aattgatacc attgcccagt atgagaaaat gggcttggaa aatcctttta
     7501 tcatcattga taccaatcat gacaattctg gtaagcagta tattgaacag atccgaattg
     7561 tccgccagac cttgattaac cgtgcttgga atgaaaaaat taagcagttc gttcgtggtt
     7621 ttatgattga gtcttatctg gaagatggtc gacaaaatga gccagaagta tttggtaagt
     7681 ctatcacaga cccttgcctg ggttgggata acacagaagc tcttgtcaga gaaatttaca
     7741 aaacgttagg agaataagat ggcatttatt gaaaaaggtc aagaaatcga tatggaagtc
     7801 atcaaggctg aaacccaatt gtctgcagaa gccttgagac tcaaggaaag ccgtgacagg
     7861 gaattggcag atattatttc aggggaagat gaccgtattc tcttggtgat tggtccttgc
     7921 tcttctgata atgaagaggc ggtcttggaa tatgctcgcc gtttatccgc cttgcaaaag
     7981 aaggtagcgg acaagatttt catggtcatg cgcgtgtata ctgctaagcc tcgtaccaat
     8041 ggagacggct ataaaggatt ggttcaccag ccagatactt ctaaggctcc aagcctgatt
     8101 aacggcttgc aggctgtgcg ccagttgcac taccgcgtga ttacagagac tggtttgaca
     8161 acggcagatg agatgcttta tccgtcaaat ctgatcttgg tggatgactt ggtcagctac
     8221 catgccgttg gagctcgttc tgtggaagac caagagcacc gctttgtggc ttctgggatt
     8281 gatgcaccag tagggatgaa aaatccaacc tcaggaaatt tgggtgttat gtttaacgcc
     8341 atctatgctg ctcaaaacaa gcaaaccttc ctttatcatg ggcaggaagt tgagacatca
     8401 ggtaatcctt tggcccatgt tatcctccgt ggagcagtca acgagtatgg caattatatg
     8461 ccgaattact actatgaaaa cctactccaa gccattgaac gatatgaaac catgggactt
     8521 gaaaatcctt ttatcctcat tgacaccaac catgataact caggcaagca atatatggag
     8581 cagattcgaa ttgttcgcca gaccttgcag aatcgtgatt ggaatgagaa aattaaaaag
     8641 acggttcgag gatttatgat tgaatcttac ctagcagatg gtcgtcaaaa ccaaccagag
     8701 atctttggtt gctctattac tgacccttgc ctaggttggg aaaatacaga ggccttggta
     8761 gaagagattt atgttacctt gacaaaataa gtgaaaagga tggagttggg gaatctcaac
     8821 tccttttgat gagaatgata gttggacacg gaattgacat cgaagaattg gcttcgatag
     8881 aaagcgcagt tacacgacat gaaggatttg ctaagcgtgt actgaccgct caggaaatgg
     8941 agcgcttcac cagtctcaaa ggacgcaggc aaatagaata tttagctggt cgctggtcgg
     9001 ctaaggaggc cttttccaag gctatgggaa cgggcattag caagctcggt tttcaggatt
     9061 tggaagtctt gaacaatgaa cgtggggcgc cttattttag tcaggcacca ttttcaggaa
     9121 agatttggct gtctatcagc cacaccgatc agtttgtgac agccagtgtc attttggagg
     9181 aaaatcatga aagctagtcc acatagacca accaaggctc tgattcatct gggagctatt
     9241 cgacaaaata ttcagcaaat gggggctcat atccctcaag gaacgctcaa gttggctgtg
     9301 gtcaaggcca atgcttatgg tcatggagct gttgccgttg ccaaggcaat tcaagatgat
     9361 gttgatggct tttgcgtttc caatatcgat gaagccattg aactcagaca agctggactc
     9421 agcaagccaa tcctcatttt aggagtttct gaaatcgaag ctgttgctct agctaaagaa
     9481 tatgacttca ccttgacagt ggctggactg gagtggattc aagcactctt agataaggaa
     9541 gtggacctaa ctggattgac agtccacctc aagattgatt cagggatggg acggattggt
     9601 tttagagagg caagtgaggt tgagcaggct caagatttgc tccaacaaca cggtgtttgt
     9661 gttgaaggaa tctttaccca ctttgctact gctgatgagg aatcagatga ctattttaat
     9721 gcccagttag aacggtttaa aactatttta gctagtatga aggaagttcc agagctggtt
     9781 catgctagca attctgcaac gactctttgg catgtagaga ctattttcaa tgcggttcgt
     9841 atgggagatg ccatgtatgg cctcaatcca agtggagcgg tcttggattt gccttatgat
     9901 ttgataccgg ccttgacctt ggagtctgct ctggttcatg tcaagacagt tccagctgga
     9961 gcttgcatgg gctatggagc aacttatcaa gcggatagcg agcaagtcat cgcgaccgtg
    10021 ccaatcgggt atgcagatgg atggacaaga gacatgcaaa atttctctgt cttggtagat
    10081 ggccaagctt gcccaattgt cggcagggtt tcgatggacc aaatcactat tcgattgcct
    10141 aagccttacc cactcggaac caaggtaacc ttgattggct ccaatgggga taaggaaatc
    10201 actgcaactc aggtagcgac ctaccgcgta accattaact atgaggtggt ttgcctcctc
    10261 agcgaccgta ttccgagaga atattattag aaaagaaagg agtggagcat gaatctacat
    10321 caacccttgc atgtcttgcc tggtgtggga ccaaagtcag cagaaaaata tgccaaacta
    10381 ggaattgaaa acttgcaaga tctcttgctc tactttcctt tccgttatga agacttcaaa
    10441 accaagcagg tgctggagct ggaagacggt gagaaggcag ttctttctgg tcaggtagtg
    10501 actcctgcta gtgtccagta ttatggtttc aagcgcaatc gcctgcgttt tagtctcaag
    10561 cagggagagg tcgtttttgc ggtgaatttc tttaaccagc cctatctggc tgataaaata
    10621 gagttgggag caacccttgc tgtctttgga aaatgggacc gcgctaaggc tagtctgact
    10681 gggatgaagg ttctggctca ggtagaagat gacctccagc ctgtctatcg tctggctcag
    10741 ggaatcagtc aggccagtct ggttaaggtc atcaagacgg cttttgatca gggactggac
    10801 ctcttgatag aagaaaatct gccccagtct ttactagaca aatacaaact catgtcccgt
    10861 tgtcaggcag tccgagctat gcattttcca aaggatttgg cagaatacaa gcaggctctt
    10921 cgccgtatca agtttgagga actcttttat ttccaaatgc agttgcagac gctcaagtct
    10981 gaaaatagag ttcagggaag tggtctggtt ctgaattggt ctcaggaaaa agtgacagca
    11041 gttaaagtaa gtcttccttt tgccctgacc caagctcagg aaaagagttt gcaggaaatt
    11101 ttaactgata tgaagtccga ccaccacatg aatcgtctcc tacaagggga tgtggggagt
    11161 ggaaaaacgg tagtcgctgg cttggccatg tttgcggcag tgacagcagg ttatcaggct
    11221 gccctaatgg taccaacaga aatcctcgca gagcaacact ttgagagttt acagaacctt
    11281 tttcccaatt tgaaactggc tctcttgaca ggttccttga aagctgcaga aaagagagaa
    11341 gtcttggaga ccattgccaa gggtgaggct gatttgatta taggaactca cgctctgata
    11401 caagatgggg tggagtatgc tcgtcttggt ttgattatta tcgatgagca gcaccgtttt
    11461 ggtgtagggc aaaggcgtat tttacgggaa aaaggtgaca atccagatgt cctcatgatg
    11521 acggcgactc ccattccacg gacgcttgcc atcacagcct ttggagatat ggatgtttcc
    11581 attatcgacc agatgccagc aggtcggaag cctattgtga cgcgctggat caaacatgag
    11641 caactacctc aggtcttgac ttggttagag ggggaaattc aaaaaggttc ccaagcctat
    11701 gtcatctctc ctttgattga agaatcagaa gctctagatt tgaaaaatgc cattgcctta
    11761 tcagaggagt tgacgactca ttttgcaggc aaggcagagg tggctcttct acatggtagg
    11821 atgaagagtg acgaaaaaga ccagatcatg caggatttca aggagagaaa gacggatatt
    11881 ctggtttcta cgacggttat tgaggttggg gtcaacgttc ccaatgcgac tgtcatgatt
    11941 atcatggatg ccgatcgctt cggtctcagt caacttcacc agcttagagg tcgtgtcggt
    12001 cggggggaca agcagtccta cgctgttctc gttgccaatc ccaagacgga ttctgggaaa
    12061 gaccgcatgc gcatcatgac agaaacgacc aatggatttg tccttgcgga ggaagatttg
    12121 aaaatgcgtg gttctggtga gatttttgga accagacagt caggacttcc agagttccaa
    12181 gtggctgata ttatcgaaga ttttccgatt ttagaagaag caagaaaggt tgctagctac
    12241 attagttcta tagaagcttg gcaagaagat ccagagtggt gcatgattgc ccttcatctg
    12301 gaaaagaaag aacatctgga ttaagctttc tctaaggaaa acttaagcta gtttttaggt
    12361 ttggctctta tactaaagtc atcaaaaaga aacgaggact ctcatatgac agtaacgatt
    12421 aaagtaaatt accaaaccac tttccaaaag aaggaagcaa aaaactagta taaacagaag
    12481 agagagcgaa atgctctttt tcgtttctaa aactactttc agcccatcat cctaaaagta
    12541 aagaatctaa attcactttc tatttatcct tctttcttgc attgattaca tagatatgct
    12601 acagttgtgg taacgattac aaaataaaag gagcatgcta tgaaaaatcc agctttgcta
    12661 gaagaaatta agacctatag aggaagggat gaggttccgg aagactttga tgctttctgg
    12721 gatggggaag tgaaaaatgt ttccacgctt ccatcctacc acttggagga aagagatttc
    12781 cacattcctc aagtcaagtg ctatgagtta acatttgaag gaagcaagga aggaaaggtc
    12841 tatgcacgca ttgttcttcc aaagagtgag gagaaggttc cactaatctt ccattttcat
    12901 ggttatatgg gacgtggctg ggactgggcc gacatgctgg gcttcaccgt agctggttac
    12961 ggtgttgttt ccatggatgt gcggggccag tcaggttact cacaagacgg cttgcgttct
    13021 cctttaggaa ataccgtgaa ggggcatatt atccgtggtg ctatggaagg tcgggaccac
    13081 ctcttttata aggatgttta tctggatatt taccagttgg tcgaaattgt tgctagtctg
    13141 tctcaggttg atgagaagcg tctttctagc tatggtgcct cacaaggagg ggctctagct
    13201 ctagttgcag cagcgctcaa tcctcgaatt cagaaaacag ttgccattta tcccttcttg
    13261 tcagacttca gacgggtgat tgagattggt aatactagcg aggcttacga cgaacttttc
    13321 cgttatttca agtttcacga ccccttccat gaaacagagg aggaaatcat ggcgaccctt
    13381 gcctatatcg atgtcaaaaa tcttgcccat cgtatccaag gtgaggttaa gatgattacg
    13441 ggcttggacg acgatgtttg ctatcccatt acccagtttg cgatttataa tcgtctgacc
    13501 tgcgataaaa cctatcgcat catgcctgag tatgctcacg aagccatgaa tgtatttgtc
    13561 aatgaccaag tctacaactg gctctgtgga agtgagattc cttttaaata tctaaaataa
    13621 ggagtcgact ctaagcacaa aatcttaaaa attacaaaca cgcatagtat caggggatta
    13681 aaaaaacttg atactatgcg ttttatcatg gaaatatagt aaaatgaaac aagaatagga
    13741 caaaacgatc aggacagtca aatcgatttc taacaatgtt ttagaagcaa atgtgtacta
    13801 ttctagtttc aatctattat atttatagaa ttttttgttg ctagatttgt caaattgctt
    13861 aaaataattt ttttcagaaa gcaaaagccg atacctatcg agtagggtag ttcttgctat
    13921 cgtcaggctt gtctgtaggt gttaatactt ttcaaaaatc tctttaaacc acgtcagctt
    13981 cgcctcgccg tatatatgtt actgacttcg tcagttctat ctgccacctc aaaacggtg
//
LOCUS       DAVLCS010000050        13808 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLCS010000050 DAVLCS010000000
VERSION     DAVLCS010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13808
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.050"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(177..1592)
                     /locus_tag="VXC78_001806"
     CDS             complement(177..1592)
                     /locus_tag="VXC78_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0583830.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1605..3443)
                     /locus_tag="VXC78_001807"
     CDS             complement(1605..3443)
                     /locus_tag="VXC78_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0583831.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3461..4300)
                     /locus_tag="VXC78_001808"
     CDS             complement(3461..4300)
                     /locus_tag="VXC78_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0583832.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4600..7158)
                     /locus_tag="VXC78_001809"
     CDS             complement(4600..7158)
                     /locus_tag="VXC78_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0583833.1"
                     /translation="MERSQFEEMFQLQSSRLTTQEKLQLFTSVFAGRYDVYAKNFINE
                     QGKIQYFPSYDYGWKQLPPEKRSFQTLTNSVLKSHFRGEAAIGIFPMHLDDSCYFLVL
                     DLDEGDWKEAGLTIRRIARERQMEAHLEISRSGYGLHIWFFFEEAILSRKARLFGKKL
                     LELAMQESMQLSFDSFDRMFPNQDVLPKGGFDNLISLPFQGEAYHQGRTVFVDEQFQP
                     YEDQWRYLQEIQKISTAKVALLIQEELGKQELDKELKIVLSNMIQLEKSSVTPKTLFF
                     LKNMASFSNPEFYLKQAMRQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVSV
                     EDRRKVQRSISVEFKGELTFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKT
                     KTIILVHNKQLLDQWLDRLNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKL
                     VDVVMIQSLFKLENSQSLLDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPE
                     RKNGHEPIVFQRIGEILHTADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWI
                     ATDSARNQLILKDILAQVAEGRNILVLVNRIQQIDVFEKLLKEKEVDGCYIISGKTKV
                     RERTSLLETLEQLDKGFVLLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIH
                     RNYKDKSLVRIFDYVDIHVPYLEKMFQKRQVAYRKMDYRVIEGEEKQFVYVDSRYEKV
                     LREDLAGERQECLLILPYVHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKI
                     KVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTILRLESASIVSELVAGLR"
     gene            7706..8906
                     /locus_tag="VXC78_001810"
                     /pseudo
     CDS             7706..8906
                     /locus_tag="VXC78_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9021..9824)
                     /locus_tag="VXC78_001811"
     CDS             complement(9021..9824)
                     /locus_tag="VXC78_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV0583834.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(10105..10860)
                     /locus_tag="VXC78_001812"
     CDS             complement(10105..10860)
                     /locus_tag="VXC78_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV0583835.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCFSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(10930..13581)
                     /locus_tag="VXC78_001813"
     CDS             complement(10930..13581)
                     /locus_tag="VXC78_001813"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV0583836.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(13593..>13808)
                     /locus_tag="VXC78_001814"
     CDS             complement(13593..>13808)
                     /locus_tag="VXC78_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV0583837.1"
                     /translation="LNHNTLVDIKSKLESLKLKHSRYYISKISKYDLKYNPGNYTMSP
                     LAAFAEIEEIYIELSKIGLVKIVNKSN"
BASE COUNT         4359 a         2910 c         2197 g         4342 t
ORIGIN      
        1 ataaccaatc tatcctaagt taactattta taatcggctc tctgtaacaa aattaaatta
       61 attaatcccc ctataaaata aagaggttta gaatttgatg tcttccaaac ctctttattt
      121 catatttaat gagatgctgc cttaaccgtg ataatatcta atcatcaata aacaaactat
      181 ttgaataagg attctccatt tgattcaatc actcctttat accaagtaaa ggacattttc
      241 ttatatcgat tgaatgtgcc atttccatca tcatttcgat caacataaat gagaccgtac
      301 ctcttagaaa gctgtgcagt ggacatagaa acgcagtcaa tacatcccca agacgtatag
      361 cccataattt ccacaccatc ttgtagagct tcagctactt gcaataaatg ttctttcata
      421 tactgaattc tataatcatc ttggactgtt aagttattaa attcatcttt tattagttga
      481 tctttagcac ctaatccgtt ttccactata aataatggaa tttgataacg gtcataatat
      541 ctatttaaaa ttatacgtag tccaattgga tcaatttgcc atccccactc agaagactct
      601 aaataaggat ttactaaacc accaataata ttcccttctc ctgaattata ctgtgttgga
      661 agagcagatt gagtcacact catgtaatag ctaaaggata aaaaatctac agtataattt
      721 tttaataact ctgcatcttc agctgcaaac tctatgttaa tgtcattttc cttaaaatat
      781 ctttttgcat aattcggata ataacctcta acatgcacat ctgaaaatag ataatttaga
      841 ttctcatact catgagtcgc ccatacatct tttggatttg gagtcattgg ataagctggc
      901 atagctaata ccatacaccc caccttaaac tctgaattaa tctcacgagc aatttttgta
      961 accaaactcg aggcgactaa ttcatgatgt atagcttgat ataattcttg tttcgaaaga
     1021 ttctccttag gtatatctat tcctccacta gtaaacggta attccaaaac agagtttact
     1081 tcgttaaatg taagccaata tttaacttta tctttatacc tttctaaaac tgttcgagca
     1141 aatttttcat aaaaatgaat cattctccta tcaatccatc catgatattt tcttgctaaa
     1201 tataatggag tctcatagtg tgaaagagtt acaagtggtt ctatcccgtg agcatgtagt
     1261 tcatcaaaca attcatcata atatttcaac ccagcttcgt taggttcttc ctcatctcct
     1321 tttggaaaaa ttctactcca tgcaatagaa gtacgaaaaa cattaaagcc catttcagaa
     1381 aacaaggata tatcttcctt atatttatga taaaaatcaa tacctatcaa ttttaagtta
     1441 tcttctgtag gattttctgt tgcttctcct aatccacctt tgggtaacac atcctgaact
     1501 gataagccct taccatcttc attatatgct ccctctactt gattagctgc aacagctcca
     1561 ccccaaagaa aatcatctgg aaaaatggtc ataactttcc tccattataa tattaccagt
     1621 aattccttag aatgctcgat tgtctgatta ttaggtaata ctaatacatc tagaaaatca
     1681 ttggtattcg ttacaattac tggtgtaact gtttcgtagc ctttagtctt gattaaattc
     1741 aagtccattt caaaaatcaa ctgatttttg aaaactctgt ctccttcttc tacatgacta
     1801 ataaaacctt gaccttttag ctcaacagta tctaatccaa tatgaattag taactcaaca
     1861 ccctcatcac tcttcaatcc aattgcgtgc ttagtcggaa aaatatttgt aattttccca
     1921 tcaaatggtg cataaacctt accttcactt ggaataatcg ctactccgtc tccaattagt
     1981 ttatctgaaa atgttttatc ctggacatcg cttaacggaa tgatttctcc tgatatagga
     2041 gaaaatatca tttttttatt tgaaactcca gctttaactt ctaaattgct agaactctct
     2101 tcttcatcga ttccaaatat ataagctaat acaaaggtaa taacaaccga aataaccgcc
     2161 acaattaaag catttacaat atttgatggc acatcagaat aaataaattg aggcaacgct
     2221 atcaaagatg ggacagcaaa tagatacgct ttaacactag taagacctgc aaataatccc
     2281 gctaatccac caccaatcat agctgcataa agcggttttt tatattttaa agtcacacca
     2341 tataatgcag gttcggtaat ccctgcaagt aaggctgaga aacctgctgc aaaagcaatt
     2401 tgttttgtat tattattttt actctttaat gcaacagcca tcgaagcagc cccttgagct
     2461 aagtttgacc ctaacattgc tggaagaatt aatacgtctg gagtagcaat agatgccgcc
     2521 aaaaaaatag gtgcaaaagc ccaatgcatt ccagtcataa caataaatgg cataatagca
     2581 ccaagaatag ctaatgtaag ccatccagct acaccataca tttgcccaac tagatttgat
     2641 aatccttcac caacaattac tccaataggc ccgactacaa ctaaggcaat acagcttgat
     2701 actaataata ctagcgtagg ttgcaaaaaa ctcttagtaa cagctggtgt taatttagca
     2761 atcatttttt caatatattt catcaaccaa accataataa gaattggaac gactgacgaa
     2821 ccataactag ctggtgtcac aggtacacca aataaactaa gaggattccc tgattgcacc
     2881 atttgaacaa aatttggatg gagaagtaca cctgctacag acatagctaa tgtagatgtt
     2941 acttttaatt tttgtgatgc agaataagct aataacagcg gtaagaaata atatggagca
     3001 tccccaaaaa atgtcaaaaa agcaatagtc tgagaatctg attgcaatat accaagcatt
     3061 ggtaaaataa ttaccaagac tttcagcata cctcccccta acattgctgg aatgattgga
     3121 gtcatggaac cagcgatata ctcaatgatt ctttctaaaa tattcccttt gtgcccttga
     3181 acaactgaat cggattcaaa attgccaagt ttaacgaatt ctttataata attagctaca
     3241 tcattaccaa gtataatttg atattgtcca ttctttttca taatacctat tacacctggt
     3301 atcttcttca catcatcatc attgactaaa ttttcatctt ttaattctaa tcttaaacgt
     3361 gttacacaat gggtaactct attgacattt ttttcacctc caattacatc gaggattttt
     3421 tgtaccgtat ctttataact catggtattc tcctattcta ttaatctaaa ttttttgtta
     3481 agcgacgaat atgagccatc aaataaacta attcactaga agtcagcaaa taattgtact
     3541 ccgtttgtat aaacattgcc acctgttcac cacattcata ttctctagga tatttatttt
     3601 tcattaatgc taacaagtct tcatcatcat cgtcacaata agttgtattt tcaaccaagc
     3661 gatgggcaaa taattttata tgagttatga atctataata atcaatagaa tcttggttaa
     3721 actcagtaca atagaaatct tgaatgattt tctcaattcc cataattatt tcagtgattt
     3781 tatacgactc ttgaaaatta ttttctaaat tagcattaac aaaatgtagc gctatgaatg
     3841 cagcttcgtc aattggaagt tcaataccta actctttttt tattatttgt aaagcccttt
     3901 tcccaagttc aaattcttct ttataatatt tcgatatttc ccagcgtagg ggattcgaaa
     3961 taataatccc ttctttataa cgttctatgc tcgaagaaat atgatccgtt aaattaatat
     4021 agataatttc atcaaaatta ttacccaatg ttattttacc taggttaatt attttttcgg
     4081 tgatgtacac caactccaaa ggaacgttaa taaacatctc tgtaaaacgg gtcatattat
     4141 ctctattttt gagaaaaaaa cttttctcaa tatcaattgg atttacttta tctccagttt
     4201 ttcttccaaa agctattccc cttccaaaaa gaagaatatc gatatctttt ttactttgcg
     4261 caattacggc attgtggttt agtattcgtt ttatgatcat aaaatttccc ttttaaaata
     4321 aaaggaacct acttaaaaac atcaagaaac ttcttctgat gtgattaaat aggttcctgc
     4381 tcacttgtat tagtgataac atccttttat ttcaattttt aatggtgaca tgaagcttaa
     4441 ataattaata actctgtaac cgtttttatt ttatgatatt tcaatctatt tgtcaagtac
     4501 ttataaaaat ttttttattt tgtgtgattc gaatgtgata atggcaacag tctcactaaa
     4561 gaaatgaaaa tcatacatag aaatttttaa aaattttctc tatcgtaaac ctgccactag
     4621 ttcagaaact atactagctg attccaaacg taatatggtc atctcatcta ccttccctaa
     4681 taatggcatt gcaccatacc aaacaatagt cttattcacc aaaagaatag gcgttactat
     4741 ttttgattga gtaaaagaca ctttaatttt ctggctcttc aactggtcta gccatgcttt
     4801 atttgcaacc gtctctggta tacatatctc aatttgacta atcctaaatt cttttagaaa
     4861 attcatcagt tttgtctggt gcacataagg taaaataagc agacattcct gtctttcccc
     4921 tgctaagtcc tctctcaaca ccttctcata tctactatca acataaacga attgtttctc
     4981 ctcaccctcg atgacacgat aatccatctt tcgataagct acttgtcgtt tctgaaacat
     5041 cttttctaaa taaggaacat gaatatccac ataatcgaaa atacgcacca aagacttatc
     5101 cttgtagttt ctatgaatcc gacctgcata ctgaattaaa ttatttttcc aagaaaaggg
     5161 tgctgccaag ataagcgtgt ccaactgagg taagtcaaaa ccttcgccaa tgtattttcc
     5221 agtagacaac aaaacaaacc ctttatctaa ctgttctaac gtctccagta aactcgttct
     5281 ttctcggact ttggtttttc cgctaataat gtaacagcca tcaacctctt tctctttcaa
     5341 taacttttca aagacatcta tctgttgaat tcgattaact aaaaccaaga tattccgtcc
     5401 ttctgccact tgggctagaa tatccttgag aatcaactga ttcctcgctg agtctgtagc
     5461 aatccaatca ctgagctgta taaaattact tgctttggtc ttttcaatct ccaaatgacc
     5521 aaaagaagtg aatcttaatt gcaattgccg tttaaaatcc gtttccctct tatcagcagt
     5581 atggagtatc tcaccaattc tctgaaaaac aataggctca tgaccattct tacgctcagg
     5641 cgtagccgtc aaaccgtaaa gatacttccc tctaaactga gcaacaactt tttcaaacat
     5701 caaggcagag acatgatgac actcatccac aatcatcatc tcatactcat ccaaaagact
     5761 ttgactattt tccaacttaa atagagattg aatcataacg acatcaacca gtttactcag
     5821 ccatttctta gtcccaccgt actgtccaac atagccgatt accttttcac gacctgatgc
     5881 cgtataacgg atagcctcct cctcttcgaa agtcaaaaag cagtttaagc gatctagcca
     5941 ttggtctaag agttgcttat tatggactag aataattgtt tttgttttcc gttcagagat
     6001 aagagcagca cctaaaacgg tcttcccaaa accagtctcc gcatgaagta aaccattttc
     6061 tttagaagtc atatctgaca gggctaactc ttgctcaaaa gtgagttctc ccttaaattc
     6121 cacgctaata gacctttgta cctttctcct atcttccaca gatacctgct taaatttatc
     6181 ttgcaatgga tacagcaaac ctcttggcaa ccataaataa tgatcggatt ctccaaataa
     6241 atacattctc tcaggaattt gataggttgg ctgtcgcata gcctgcttta aataaaattc
     6301 gggattagaa aatgaagcca tatttttcaa gaaaaacagt gtcttgggtg tcacagacga
     6361 tttttcaagt tggatcatat tggataagac gatcttcaac tccttgtcca attcttgctt
     6421 gcctaactcc tcttggatta acagtgccac tttagcagtt gaaatcttct gaatttcttg
     6481 tagatacctc cattgatctt cataaggctg aaactgttca tccacaaaga ccgttcgccc
     6541 ttgatgataa gcttctcctt gaaaaggaag ggaaattaaa ttatcaaatc cacctttagg
     6601 aagaacatcc tgatttggaa acatgcgatc aaaagaatca aaggacagtt gcatactttc
     6661 ctgcatagcc aattctaata gtttctttcc aaacaggcga gcctttcgac tcagaatcgc
     6721 ttcctcaaag aagaaccaaa tatggagtcc gtaacccgaa cgagaaatct ctaaatgggc
     6781 ttccatctgg cgttccctgg ctattcttcg aatggttaaa ccagcttctt tccaatctcc
     6841 ttcatccaaa tccagtacca aaaaataaca gctatcatct aagtgcatag gaaagatacc
     6901 gatagctgcc tccccacgaa aatgagattt caaaacggag ttcgtcaatg tctggaaact
     6961 ccgtttttca ggtggcaact gcttccaacc ataatcatag gaaggaaaat actgaatttt
     7021 cccttgttca ttgataaaat tcttagcata aacatcataa cggccagcaa acacagaggt
     7081 aaacaattgt aatttttctt gcgtcgtcaa gcgactactt tgaagttgga acatctcctc
     7141 gaactgagag cgttccataa caaactgact cttgtcttta agacgtttat agtggaatga
     7201 aataagatat gaacaaattg attaggaaaa tcaaattaat ttatagaaat cttttagcag
     7261 tcatggcgtc ctattccaga ttcaaaatgc tatacacaag aaaaactcac tatccccatt
     7321 aaaagaagaa aagacatcaa ggacttctac cacaattcca tccaaagaca caaaaacagc
     7381 cataagagtc acctccttga ttcctatagg ctgattataa caagactggc tgaaattgta
     7441 catgaaaata aaatcctaat agtactcatt ttgtatgtga ctaatattcc gtctcgctcc
     7501 agaaggtacg aagtaaatag agtttaaacg agcagtctat aaaattcaaa aaacgcatat
     7561 tatcaagcga cctaaaactt tgggctctat aatatttgta gtgggtaaat tccctatgga
     7621 tattatggag cctattttgg gtagaaaaaa agtcccataa gatctataat gaaaagcgac
     7681 aaaacaactc attagaaaga atcatatgga acaattacat tttatcacaa aattactaga
     7741 cattaaagac cctataaaat tccttacctt gaaacgactg gtatgcctac tagaattctc
     7801 cttagaaaac gtcgttttaa gtgctatcat tgcttgaaaa tgatggtcgc tgaaacttct
     7861 atcgtcaaga aaaatcacca aattcctcgt attatcaacc aaaagattgc gcaaaagtta
     7921 attgaaaaga tttctatgac cgatattgcc catcagctgg ccatttcaac ttcaactgtc
     7981 attcgaaagc tcaatgactt ccactttgag tgtaatttta gaaatctgcc taagattatg
     8041 tcttgggacg ttgaaacagt ccggggagtg actgtttcaa tcgggagatg gagatgagct
     8101 ttattgcgca agattttgaa aagctcgata tcatcactgt tcttgagggt agaacacaag
     8161 ctgtcatccg agatcacttt cttaaatatg atagagccgt ccgatgtcgc gtcaaaatta
     8221 ttactatgga tatgtttagt ccttactatg acttagctaa acagcttcgc tttcaaattt
     8281 ctaggctcag gctgaaacag tctcccagac tgtttcactc ccgaatgcta aaatcgttct
     8341 tgatcgcttt catattgtac aacatcttag ccgtgctatg agtcgtgtgc gtgtccaaat
     8401 catgaatcag tttcatcgaa aatcccatga atacaaggct atcaagcgct actggaaact
     8461 cattcaacag gatagccgta aactcagcga taaacatttt tatcgcccta cttttcgtat
     8521 gcatttaacc aataaagaga ttttagacaa gcttttgagc tattcacaag acttgaaaca
     8581 tcactatcag ctctatcaac tcttgctgtt tcactttcag aataaggaac cggagaaatt
     8641 tttcgaactt atcgaggaca atcttaagca ggttcatcct atttttcaga ctgtctttaa
     8701 aaccttcctc aaagataaag aaaaggttat caacgccctt caactacact attctaatgc
     8761 caaactggaa gcgaccaata atctcatcaa acttatcaag cgcaatgcct ttggttttcg
     8821 aaactttgaa aacttcaaaa aaacggattt ttatcgctct gaacatcaaa aaagaaagga
     8881 cgaaatttgt cctttctcga acttagcttt tcttcaaccc actacaattg acaaagagcc
     8941 aaactttgat gatatacgtt ttcttgtgag aatatttact tcattttttc ctaaaattca
     9001 atgtttactc agtatttgga ttatgaaaaa tcgaggtcta aatctagata cattttttct
     9061 gaagacaaat cattttgacc accgagcaag agattttcaa aaaaagctgt taaaaactca
     9121 ggacgtcgct gtaaaatctt tgcattatct aataccaagg catcacgaaa atacttggaa
     9181 tgttgctgaa atggtatatt atcaatatca aaaccaaact cacgaagata ctgaatcaaa
     9241 aagaccgtta ctgtccgagt gtttccttcg cgaaatggat gaatctgcca gattcctgaa
     9301 ataaaatgct ggatttgttt aaccacatcc gcctgagtta gtgtcgcata tgcaacttgt
     9361 ttttcctgat taaaatcata atctaaggtc atttgaatca tggagtaatc agagtacaca
     9421 acactttcac cattcaaaac aggttcattc tttgtgatat tggtctgacg aaattgcccc
     9481 accggaatag agggttcaaa tatatcttga aacaactcct tatgaatagc aagtaaggtc
     9541 gcaggactaa agctaaagcc tcttcgagac aatagttcta caatacgtag agaaaccaag
     9601 tctgcctctt ccgtacttgc atcaatagta tggtgataag ccgttgcatc ctcataaacc
     9661 tgctcataag tcagttctcc ccgggactgt ttctcagcca aagattccat atacgctgat
     9721 ggcactagat tgtcaacttt ctgcagacca aaacctatcc gccataaatc acgcttcgct
     9781 tcataagaca agtttggatt gtcaatgttg taagttggtt gcatagaaat atcctttcaa
     9841 ttgtttttct tcattaccag taaatcacga aattggttgg aaactggctt aaactataaa
     9901 aagtcctcac aataggttct atgatatata tatatatata cttcatgtaa ataataaaag
     9961 agttataatc agcactactg ataaattcaa taccgatttc gccatcttaa aacttagtca
    10021 aacgaatacc gttgatttcc agttcattaa gtcgttgacc tgtcaagact tctcgttcct
    10081 tcaactggaa aagttaaggg ggaactaata caaatcctct acgcttctat attcaatgat
    10141 ttcatttttg ataatattct ttttaaactc aaaatgtttt aaaggattat cgattaacac
    10201 taactttgga atatcatcta gatttgtgac caaggataaa ataaaatccg attgaaactc
    10261 cttgactttt tcaaattctt ttgcagttaa acgcacacgc cccttagatt ttcggatacc
    10321 ttttacttcg gcaaggtaag aatactcttg gacatctacc tgaaagtcat atccatcacc
    10381 ataaagacgg gcatcggtta actgtccacc ttggaatttt tcttctttat caaaatgaag
    10441 gataaaataa ttctcagcct ccattcccgt ttcctgtaga cgtttgaatt tagttcgaac
    10501 tattggtttt tcaacgatgg ttatgcctgt tttcttccct tcactggcaa gtaacatttt
    10561 aactatttca gcataactat gaacatcttc atttccaaac atcatatcaa ttaaatcttt
    10621 acgaaaacga taaacttcag ctttctgcca ccaacctttt cgattattgt caaaataagg
    10681 atcaaataaa tccattctat tttttacaac tccagttgtt tcagcaattc ccagagaaac
    10741 cacatagcga taaaactccg acttgctaaa gcattgaaat tcttttataa aaagcttgtc
    10801 aaacttggca agaccgtagc caattaaatt taacaattca taatgagggt gtttggacat
    10861 cactttctcc atcaatagat attgatttca ttataccaaa aaacacggct catcaccgtg
    10921 tttctgtgtt tatttcacca acttcttcat ctcatcaata cgtgctacgg tcacatcata
    10981 cttggcttgg tagtcggctt gtttgtcttt ttctttttgg acaacttctg gtttagcgtt
    11041 ggcgacgaag cgttcgttag agagtttctt accaaccatg tccagttctt tttgccattt
    11101 agcgagttct ttgtcgagac gagctagttc ttcttcaaca ttgaggagat cggccagtgg
    11161 caagaagatt tcggctcctg taataacgct tgacatagcc agttcaggtg cagggatggt
    11221 tgatgcgatt tccaagtgtt ctggatttgt aaagcgtttg atatagttga cattgctgtt
    11281 aaagaaggct tccaagtcac tatcgcttgt cttaacaagg atggtgatag gcttgcttgg
    11341 tgctacattt acttccgcac gcgcattccg aacagcacga attaagtctt tgagactttc
    11401 cacaccagtg tgagccgcaa ggtcttcaaa ggctagatta acagttgggt atgcagctgt
    11461 cacgatagaa ccttctgaga tttgtccaaa gatttcctct gtcacgaatg gcatgattgg
    11521 gtgaaggaga cgaaggatct tgtccaaagt gtatagtaga acagaacgtg tgatgacttt
    11581 ctcttcttcg ttatcgctat aaaggacttc cttggtcaac tcaacatacc agttggcaaa
    11641 ttcttcccaa atgaagttgt aaaggatatg accagccaca ccaaactcga acttatcaaa
    11701 gttttcagta acttttgcaa tggtttcgtt gagattgtgg agaatccagc ggtccgtcac
    11761 attaccagcc tcacctgttg caacttttgt gacattgtca tgcgccacat ccagcgtcaa
    11821 acctccattg ttcatgagga tatagcgaga aatgttccaa atcttgttaa taaagttcca
    11881 tgaagcatcc attttctcat aagagaaacg cacgtcttgt cctggcgcag aaccgtttga
    11941 aaggaaccat cgaagggcat cggcaccgta tttctcgata acatccattg ggtcaatccc
    12001 gttaccgaga gacttagaca tcttgcgtcc ttgctcgtca cgaatgagac cgtggataag
    12061 gacgttttgg aatggttgac ggcctgtgaa ttccaatgac tggaagatca tacgagacac
    12121 ccagaagaag atgatgtcgt aacctgttac caaggttgaa gttgggaaat aacgtttaaa
    12181 gtcttctgag tcgacttcag gccagcccat ggttgaaaat ggccagaggg cagaactgaa
    12241 ccaagtatcc aagacgtctt cgtcctgagt ccatccgtca ccttctggag cttcttcgcc
    12301 gacatacatt tcaccatcag cattgtacca ggcagggatt tggtgacccc accaaagctg
    12361 acgagagata acccagtcgt ggacattttc catccattga aggaaggtat cgttgaaacg
    12421 aggtgggtag aattcgacct tgtcctctgt gtcttggttg gcaatggcgt tcttagccaa
    12481 ttggtccatc ttgacgaacc attgagtaga caagcgtggc tcaactacga cacctgtccg
    12541 ttctgagtga ccgactgaat ggacacgttt ttcgattttg acaagggcac cgatttcttc
    12601 caacttagca acgactgcct tacgagcttc aaaacgatcc atgcctgaaa attcaaaggc
    12661 aagctcattc atagttccgt cgtcgttcat gacgttgact tgtggcaagt tatgacgttg
    12721 gccaaccaag aagtcatttg gatcgtgggc aggtgtgatt ttcacgacac cagtaccaaa
    12781 ctcaggatct gcgtgctcat ctccaacgat tgggatgagt ttattagcga ttggaaggat
    12841 gacgttttta ccaatcaagt ccttgtagcg cgggtcttct ggattaaccg caaccgcaac
    12901 gtccccaaac atagtctcag gacgagttgt agcaacttca agggcgcgtg aaccatcttc
    12961 cagcatgtaa ttcatgtggt agaaggcacc ttctacatcc ttgtgaatca cctcaatatc
    13021 agaaagggct gtgcgagctg ctgggtccca gttgatgata aactcaccac gatagatcca
    13081 gcctttcttg taaaggtcca caaagacctt acgaacagct tttgacaaac cttcgtcaag
    13141 agtgaaacgc tcacgagaat agtctacaga aagccccatc ttgccccatt gttccttgat
    13201 ggtagtggca tattcgtctt tccattccca gaccttcgtc aagaaagact cacgacctag
    13261 gtcataacgc gtaataccct caccacgtaa gcgctcctca accttagcct gagtcgcaat
    13321 accagcgtgg tccatacctg gaagccaaag ggtatcaaag ccctgcatgc gtttttgacg
    13381 gatgatgata tcctgcaaag tcgtatccca agcgtgacca aggtgaagtt tcccagttac
    13441 gtttggtggt ggaatcacga ttgaataagg cttagccttt tgatcgcctg aaggcttgaa
    13501 aacatccgca tcaagccatt tttggtaacg accagcctca acctcggctg gattgtattt
    13561 agatgaaagt tctttagaca tgtgtgttct ccttaattac ttttattgac aattttaacc
    13621 aaaccaattt ttgaaagttc aatataaatc tcttcaattt cagcaaatgc tgcaagtggt
    13681 gacatagtat aatttccagg attatattta agatcatact tgcttatctt tgaaatataa
    13741 tacctagagt gtttcaattt taatgattcc aactttgatt taatatctac taatgtatta
    13801 tggtttaa
//
LOCUS       DAVLCS010000051        13215 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLCS010000051 DAVLCS010000000
VERSION     DAVLCS010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13215
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.051"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(387..2114)
                     /gene="ezrA"
                     /locus_tag="VXC78_001815"
     CDS             complement(387..2114)
                     /gene="ezrA"
                     /locus_tag="VXC78_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV0583838.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIDEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2196..4142)
                     /gene="gyrB"
                     /locus_tag="VXC78_001816"
     CDS             complement(2196..4142)
                     /gene="gyrB"
                     /locus_tag="VXC78_001816"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV0583839.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4157..4720)
                     /locus_tag="VXC78_001817"
     CDS             complement(4157..4720)
                     /locus_tag="VXC78_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0583840.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4805..5359)
                     /locus_tag="VXC78_001818"
     CDS             complement(4805..5359)
                     /locus_tag="VXC78_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV0583841.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5370..6593)
                     /locus_tag="VXC78_001819"
     CDS             complement(5370..6593)
                     /locus_tag="VXC78_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0583842.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6630..9080)
                     /locus_tag="VXC78_001820"
     CDS             complement(6630..9080)
                     /locus_tag="VXC78_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV0583843.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLRKKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTEASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEDFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVGHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELSQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9280..10209)
                     /locus_tag="VXC78_001821"
     CDS             complement(9280..10209)
                     /locus_tag="VXC78_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0583844.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     AQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10349..10636
                     /locus_tag="VXC78_001822"
     CDS             10349..10636
                     /locus_tag="VXC78_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV0583845.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10670..12004)
                     /gene="ciaH"
                     /locus_tag="VXC78_001823"
     CDS             complement(10670..12004)
                     /gene="ciaH"
                     /locus_tag="VXC78_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV0583846.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(11994..12668)
                     /gene="ciaR"
                     /locus_tag="VXC78_001824"
     CDS             complement(11994..12668)
                     /gene="ciaR"
                     /locus_tag="VXC78_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV0583847.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            12886..>13215
                     /locus_tag="VXC78_001825"
     CDS             12886..>13215
                     /locus_tag="VXC78_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0583848.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKI"
BASE COUNT         4040 a         2820 c         2341 g         4014 t
ORIGIN      
        1 aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttctct agtctggaga
       61 tttttcaata gacttcgtta ttggacggtt accaagttac tcaaagtaca gatttgaagc
      121 tgcagataag actgacgaaa tcactttaat actaaatgaa aatcaaaaag caaactaaga
      181 agctagcctc aggctgtact tgagtacggt aaggcgacgc tgacgtgatt tgaagagatt
      241 ttcgaagagt ataaaacact gttttgaggt ggtggataaa tcggctgggt aaaaactcaa
      301 tctcaggaga aaatgaagta aatctcccca caactataga aaaagatttg attctgctcc
      361 tcacacaata aaatcttttt cttttattaa aaacgaatcg tttcacgtgt tttctcatat
      421 gaggtaacaa agcgattggt tacaccaggc tctgccactt ccaatgcttg agaaatcttg
      481 tcaaatgaag cgtgataatc aaattctttt tcaaaaatat ctaaagcttc gttaaatgct
      541 tcttgaatgc gttcatcaaa tgagcgatag cggttagaat attgcaagag ttgctctgtc
      601 aaagttgcat attgtacaat attataagtt tccgtttcta aagcttccat atcattcgtt
      661 gcaatttcaa gaactcgggt aacagattca atgttaatca ttttttgttc taactcaacc
      721 attaaatcct cggtattatt gcttgccgta aagaataact tcaagaaagt ttgtggaata
      781 cctggcagat tgcgtttttc catgtatcgc ttgatagtat ggagacgatt gacataaaca
      841 ttggcctttt gacgtgcatt aatatcatct ttctcaattt gtgtcaggcg ctcactaact
      901 gaaatttgct catcttcaat atcttttagt tgagtttgta aatcctcaag attttcttca
      961 agaactgaat aagcttgggt tggttcttct tgatttgaag ttacctcaac aatagctgcc
     1021 tcaaaactct ctaattctgt ctgaatacga cgaacatggc ttgcagctgt ctcaggaagt
     1081 aaataggtct tgttcaaacg tgcaatatct tctcccaata aagtattatt ctctttcata
     1141 tgttgaaggt aagttggaag agttgcaagt agattttcca ctactttctg agcagcaatt
     1201 tctcgagtaa aaatatcata caaggcattg atttcctctt gtgcctgtcc attctcatat
     1261 tcggcattat ccaattccaa ctgacgaata ttctcttggt ttttcttgaa tgcttcataa
     1321 agcaagtgga aacgcgcttc aatatccgtt tcaacaaaat gataattagc atcaattagt
     1381 ttacgataac cggattccaa atcctgtaat tgatctggca attctgtaga aagcgtcgta
     1441 accaaggctg gaacacgatc cacaatatga cttaaggcca aaatgtgatt ttctgtatta
     1501 tccaaaatca ctgcggcttc cacagggtca cccgatgaat tcaaggttac aaattgtgaa
     1561 aattcagatt ggatattttc taattgtttt tcaatttcat ccaaggcttg accatactgt
     1621 tctgaatttt cagcaactct atgctgaagt tcctcaaata aatccaaagc atgaagaaca
     1681 cgaccactat ttttagattc ttgcttctct aagtctgcca aagcattgcg aattgccgca
     1741 atatcttcgt caatcaaagt aatttgactc tcaatttggt caatttgatg actggccttg
     1801 agaaaacgaa atgaatggtt atagccttct gcttcaaaga gattattttc aatatcggca
     1861 aaagagttga gagataaatc gacccatttt tgattccatt cacggaaagc cacttgactt
     1921 tgtccaatca agtgcatatt ttttacagct tctacttcat catttactgg aagattgtat
     1981 agttcttctt ttctttcttc tagcgcctct aatctcccct cgtttcgctt acgtagaaag
     2041 attgccacta cataagccag aactaaaatg actgcaattg caaccattaa ataaattagt
     2101 tgtccattag acatatcaaa ctcctttttt acttgaaaca atcgtaacga ttatatcata
     2161 ttttttagac caagggaact acttctccct attttttaga catcaagtgt actatagaca
     2221 gcattttctt cgataaactc acgacgaggc tctactcgat cccccatcaa catatcaaag
     2281 attttatctg cttctgcagc atcatctaca gaaactctag ccatcaagcg atgttcggga
     2341 tccatggttg tttcccacag ctgatgatcg tccatttcac ctagcccctt ataacgctga
     2401 atagtcggtt tggtacgacc ttcactataa cgggctaaag cttcttggag tttgatttct
     2461 tgatctgcac ccggctggat atattcttta atctcgcttc caaccttgac accatagatt
     2521 ggtggttggg caatataaac ataaccagct tctaggattg gtttcatata acgataaatc
     2581 aaggttaaaa gaagggtacg aatgtgggct ccatcgacat cggcatcggt catcaaaacg
     2641 agtttttggt aacgggcttt cgaaacatca aattctgcgc caaatcctgt tcccatggct
     2701 gtgaaaagac tacgaatttc ttcgttagct agaatcttat ccatacttgc tttttcaacg
     2761 ttcaaaatct taccgcgaat tggaaggata gcctgaaact cacggttacg accagatttg
     2821 gctgatccac cagctgagtc tccttcgacg atgaagagtt ctgtttcagc agggttatta
     2881 gaagaacagt ctgctagttt ccctggaagg ttggaaattt ccaaaccaga ttttttacgt
     2941 gtgacttcac gcgcacgctt ggcagccaca cgagccttgg cagctaaaat ccctttttcc
     3001 acgatacgtt tggcaatctg tggattttcc atgaggaaat cggagaaggc ttcactgaag
     3061 aggcgattgg taatcttgac cacttcgcta tttcccaatt tggtcttggt ttgtccttca
     3121 aactgtggat ttgggtgttt aactgagata actgcagtta atccttcgcg aacatcttcc
     3181 cctgttaaat tatcttcatt gtctttcagt aacttattct tacgagcata atcattgata
     3241 acacgagtca gtgccgtacg gaaaccttgt tcatgcgttc caccttcatg ggtatgaata
     3301 ttattggcga aactcatgac attttcatgg taacctgttg tgtactgcat ggctacctca
     3361 actgtgatat catccatctc accgtctgta tagattggtg tatcaaagat tacatccttg
     3421 ttctcgttga tatattcaac gtaactagca atcccacctt cataatgata atgcttggtt
     3481 tgttccaaac cttggcgctt atctgtaatt gaaatttgaa gaccgcgatt tagaaaggcc
     3541 aactcttgaa tccgtttatt taatttatca aaatcaaaga ttgttgtttc agtgaaaatt
     3601 tctgggtccg gtgtgaagtg aaccgttgtt ccagttctat ctgtatcccc aaccacctca
     3661 aggtctgcaa caacatgacc acgacggtat tcttggtaat gaatcttacc gtttttatgg
     3721 acatgaacgt ctaattgagt ggaaagggca ttaactactg acgaccccac cccgtgaaga
     3781 ccacctgaaa ccttgtatcc accaccgccg aactttcctc cagcatgaag gactgtaaag
     3841 acggtctcaa cagcaggacg gcctgttttt tcctgaatat cgactgggat accacgccca
     3901 tcatccacaa cagtaatcga atcatctggc tcaataaaaa cttgaatatg gctggcaaat
     3961 cctgccaagg cctcgtcaat tgagttatca acaatttccc agactagatg gtgaagacct
     4021 tcttttgagg ttgatccaat gtacatccct ggacgcatac gaacagcctc taagccctct
     4081 aaaacttgaa tttgactggc atcataatcc tgtgcctgca gatttttgat ttcttctgtc
     4141 atcttattcc tttttcttat atgtctaata cttgtcttaa attcacgata ctggtaaaca
     4201 agtgggtatc aagtcctgca gcttgacctg cttcgatatc aatcggccga tcaccaatga
     4261 caagaccaga gctaatctga tacttttctc ttaaataaag catggattcg ggatttggct
     4321 ttctcttaaa gcctgagcta gaagtcacca cttctgtaaa ataagctgct atagaggttt
     4381 tttctaaaat ttccaaaacc tgatcatttc gatgagagac caaaaaatga cggccacctt
     4441 gatttaaaat gtcttccaat aggtcagaaa ctccttcaaa taaaatcggg tgttcaagct
     4501 ctctggcttc attttccttg tacttttcta aaaaattctc taaattggga gcgaatgtct
     4561 caatcgcaaa aggagtagaa acctttaaag cttgatagac actgtcatgg tcttgtgtga
     4621 taccatacag tgccaatgtt tcaacaaatg cagctgttga agtttcataa ttatccagta
     4681 aagttccacc taaatcccag atgtaatcgt gatatttcat acccttcatt atagcatttt
     4741 tttatgaaaa aagcgatgat ttccctgagt tttccacata aaaaacgaga gaataactcc
     4801 cgttttactg atttttacca aagacatctc gatagagcat tcctgttcgt aaactctctg
     4861 cgtcccctcc tagttgctcc accaactcgt aggcaaaggc aagggctgtt gaaggacccc
     4921 gactggttgt caactgacca tctaccacta ctgtttcctt gacgtagtga ccatcaagga
     4981 tttgctcttg aacgccgtca taacaagtgt atcgcttatt tttcaatatc tctgcttgat
     5041 tgagggcaat tggtgccgca caaatggctg ctagtttctt cccttcttgc tcgaagcttt
     5101 gcaattcttg aatcaaggtc tgattatcac gtaaatgtgc agaaccaggc atacctccag
     5161 gaagaacaat catatcatag tctgataaat ctccatcaaa gacatgatct gctcttactt
     5221 ggattgcatg cgaacccgtt acttgctctt caaaaccaac catatcacat gtgatattgg
     5281 ctcgacgcaa gacatctaca actgtcaagg cttcaatttc ttcaaagccc tgagctaaca
     5341 taactgctac ttttaccatg attttctcct tatttaattt gttttaatac aacctttttc
     5401 cgtttgaatg ggacttttcc gctcttttct tcagctaaat tagtctggta actcatcgat
     5461 aaaagcaaac caacaccaat caaattactg ataatagctg atcccccttg cgaaatgaaa
     5521 ggcaagggaa tccccgtcaa aggaagtagt ccagtcacag caccgatatt ctcaaagatg
     5581 tggaagagca acatcataat caaacctgtg gaaatataag tgtagaactg gttatttgat
     5641 ttaagagtaa tcttcaacat acggtaaatc aacatgagat agagggcaat aaccaggaca
     5701 gagccaataa agccaaaatc ttctgcaata accgtaaaaa tcatatctga ctctcgaact
     5761 gggataagca gattcgaagc attaaatccc tgaccaaata agccaccact cccaatggca
     5821 atctgccctt gagcctgctg gtaagtcgtt gtttgggcaa actcaaaggg attgagccaa
     5881 gccaaaatcc gattaatttg gtaagtcggc attccaatct ggtgaagaaa agctcgtccg
     5941 tccttgctaa taaagatagc taagaaacca gcaactcctg ttacagcagt cacaaatact
     6001 gggataataa ttttccaaga aacccctgat aataaaacga ttcctgagaa aatggctaca
     6061 aaaaccaaag ccgtccccaa gtcactttga agtgctaaaa gaactaggac tggaatggta
     6121 aagagaatca tccagaaaat taacaaaaag tccagcggaa ccgtgcgtct ccattcctta
     6181 tgtttctttg taaattggac aatgacacga gccaacatga ggatatagga tatcttcata
     6241 aattctgacg gttgaaatag ggtaattcca tttattgata cccagttttt ggcacccgtt
     6301 gatgcaacta agcttggatt ataaaataca atcggcaaga tcataagtcc caagcctaaa
     6361 atatatagaa agggggtcac cttccaaaga aattctgtat taaagagcat gaccacaaaa
     6421 ccaatcacaa gccccaaggc aatccaggcg acctgctgcc ctaaaatggg cagaatatta
     6481 ttgggataat catgactaac ggctatatag atagccacca caccgatgac cagtagaaaa
     6541 aatactggca agagcaaact ataatcgact ctagagtcga gagaacgttt catatgtact
     6601 aaccttatac tttcatacaa tactatttat caaagttcat taaaaaatct atcaatagcc
     6661 tcgtcaactt cggatcgaga gatggtttta acagtcgctt cttctgctag agatgctact
     6721 atttgtttgc cgtatcgttt tccgatgatt ctcctatcca aaataagagt taaggaacgt
     6781 tggtattcac gtctcatact tcttcccaaa gcctgtttta aacgaataat ggccattggc
     6841 aattgataat cataaaaggc atttttccct tcttgactca gttcttgatt aatctttttc
     6901 gtcaagggtt cttgaggatt ttggaaagga agcctcggta caacttgaat cacaaaagga
     6961 tggcttgaaa aatcaactcc ctcccagaaa cttgctgcac caagcaagat ttgttgttca
     7021 cctttttcaa agcgtttctt tagctgatga acatccccat ttttatactg ggccaagtgg
     7081 ccaactgtaa gtaaatccga tactgctaga agcatgtctt tagcggtaaa gagaaccaaa
     7141 atcggttgct ggaaagcttg aatttccact agtaaagcag ctacctctct ggcatagact
     7201 tctaaggagg tttctgttac cagagggaaa tctttgacca tgaccacttc ttgttcctgt
     7261 tttccccgag attcaatctt gacaaattta gcttcaggat agcctaaaag gtctgccaaa
     7321 gaaaccctct gactaatctc aagagtagcc gatactccca agacttggca actctcagga
     7381 agtaaagagg acagaagagt acggcctgat tttgtagaag aaatctgaat tttcttttga
     7441 ctcgtttcag ttacttcaag ccagtaatca ccttcagctg taaaatagcg aaccagctca
     7501 tcaaagtctt ctacttccaa ttctgaaaaa tactgatgga gattgtccag agaatctaag
     7561 atatttttcc tagatttgcc agactgaaat tgttctatca agtagagaca ctcaaagcga
     7621 atactttcta gtatccgttg ttgaaccctg ttttcttctc ctactaaagc cttatcaatt
     7681 aaatcgataa tagattgtat atcgtaggtc tcttgaagca gattttctag agctaacaaa
     7741 atcttttgga cttcatcaat aatcagtaaa cggtcactga caaattcagg attatcttca
     7801 agtctggtta cgagataggc atgattagtc actaaaagct tgcaagtctc tgccctttct
     7861 tgactacgtt tccaaaaatc ttccgtcaca aataagctct gggatgataa attcccatca
     7921 tgacgaaggt ctgctagaaa atgttggtaa cggtagagtt gcccgatttc atccaaatct
     7981 cctgtctctg tctcagtaag ccagaccaag acttgcattt taaagcgtct aaataagcga
     8041 ttttcatcat tttcctgcaa ggaatgataa aaggcatcca acttcagata attttgtggt
     8101 ccctttaagc tatgaatatc tgtatggaac acttccttga ggcgtttacc ttcttcttcc
     8161 atgatttgat tttgaagaat ctttgtcgga acactaagaa caatttgtcg ctctttggat
     8221 tgagataaag cgggtaagag atagccatag gttttcccaa tccctgtcgg cgcttgaatc
     8281 agagagacag gttcatcttt caatagcaag ccaacctctt tagcaaaact ttcttgttcc
     8341 tccctcactt caaggttcaa cagagaaata tttttagaaa agtcttgaga tagttttcgt
     8401 ggctccagag aagcttccgt tttcttaaaa tatagacctt gaacttggac caagtctgga
     8461 gaactcagga tagattggtt gcgataagtt tcctcaataa ccaggtagga ctcatatagg
     8521 agagcgtcag ccatttccag caagcgttcc aagagacctt taggaagctg ggtcatcttt
     8581 ttccgtaaaa aaagaagtaa ttctgctgta gcttgggcat ctgaaagggc tgtgtgtgcg
     8641 tgtttaagag gaattcctaa ttctcgacac aaaatcggca aactatattt ttccagttca
     8701 gggaaaaaga cctgggccaa ttcgaccgta tcaacacgag ggtttcttag ctcatagcct
     8761 tcaaaaaata aattttccgc caagagatta gcatcaaact gaacattatg ggctacaaaa
     8821 atcccatcct ccaccaagtc aaatattttt ctggcaactt gcgaaaaatc aggtgcttgc
     8881 gccagacgtt ggtctgtcaa tcctgtcagt tctttgatat gagcatccaa gggttcatgt
     8941 ggattgacat ccgtcgtata gtgatcgacg atttctccgt cctcaatcac gacaattccc
     9001 acttggataa ttttagcctt actacctgtg ctagttgcct ctaaatccac cacaacatag
     9061 cgattaccaa tcgttttcat tataaaaaat tataccaaaa aaagggccat ttggcacctg
     9121 caaacatagg ataattttca aactcaagaa cactactttt cttaaaaatc ccatcgaata
     9181 gagcattcta gcctgctgat ttttgtaaaa tagtgaagaa atacgaaaaa ttgagagaag
     9241 aaatgtttgc atcttccttc tctcaacgaa tcatgtattt tatctaacca tgtcaggatc
     9301 gtagtcataa aatcctgtat caaggaaacg gtttttaggg tgaagtttac gaacttcttc
     9361 atccagcaag aaggcttgag catgactaaa gttgccctct tgaatcaagc tacgcgcttg
     9421 gataaagagt tttgcaatct caacaaagtt ctgaccagga gtgtagagcc cttctagttt
     9481 ccagcgagta aagccatgct ccaccaattc tgttaatttg atcatcaaat caaggtcatt
     9541 gttggcaaag atatgggtcc catgattatc ttcaaaaatg gaatagtggc tctctggatc
     9601 acttggctca gccaagaaga ggtcacgttt atgcgtcttt tcatcatcga tatgtgtaaa
     9661 gttatagtag ttttgcaaga gtggacgttt agaatgatgg atgacgctag caccgtaaac
     9721 caaaacttca gcaggaattt ccaaaatctc tggcattttg aaaagttcag ctgatggaat
     9781 ttcacgcgcc aaaacagcct cagatgcgcc agccttttgt ccccagaagt taatctgacg
     9841 actgctagtt accatggttg aagcatcgta gatggtctta aatgaataac catcgcggtt
     9901 aactacgtaa aagacgcctg catccccaat cgtaatatag tctgtcttga tttcttccaa
     9961 gaagtctaag aaaggcttga tacggtccat catatcttgg tgcatgagag cattgaccgc
    10021 aacgatcaat tccttaccag catcatgaac caacttagcg atttcacgta attggtcata
    10081 actaaaggtc gttggcagac gaagaccaaa atctttctca ccgacataga tacggtctac
    10141 gccagcttcg agtagttgtt caacttgttc aatactttca gcagttgctg taatgacaat
    10201 cttttccata agaaaaatta taccacattt ctccaaaatc agccatgctt tgaaaatgaa
    10261 aagggacttt attctttttg taacctttct gtaataattc tctgccgaaa aaatgataaa
    10321 ataggtatgt actgttaagg agagaatcat gcccgtaaga aaattacaat cctatgaggt
    10381 agactatcaa gaagaattaa accagcagct tcctcattac caagcttata cacctgaagc
    10441 gcaatctgat gccaatctca aggaaatcct attttttatt aatatcgctg ttttttgtat
    10501 ctgtattgct atctttagtt ttatcttttt agcattaaaa ttatcaactg ctcttgcctt
    10561 tgccgcagca atcggattca gcttacttgt tttaaaagtt caacggtcta ttatcaaacg
    10621 aaaacgtaga agataaatcc aaaatatcgc cccaattgga gcgatatttt tattttttct
    10681 ttttagatgg tgtctgaatg gcaatcttca cttcaaagat tgttcccttg ggtttattat
    10741 ctttgacagt aacagttcct tttagagcat ctacaatttg cttggctagg gataatccta
    10801 aaccaaaacc acctttttgc cgggttctag ccttgtctac tcgataaaaa cggtcaaaaa
    10861 ttttcttttt atcttctgtc gaaataccga ttccattatc agaaacaagt aaataaagat
    10921 tgcgatcggt cgccgagata agaaaatcaa tttcaccatc ctcctcagta tacttgacgg
    10981 cattatcgaa aagaatggtc atcagttgtt tcagaagaag ctgatctgtg acaattgttc
    11041 gatggatacg attttcaaaa cggaagacac gattattttc cgaagcaatc atctcatagt
    11101 ttgtgaaagt tgtattaaaa aagctagttg gaacttctgc aagctccggc ttaatcccat
    11161 catctctccg agctaagttc agcaagcttg tcgttaaaaa acgcatattt cggacttctt
    11221 ccaaactcga tgcaatgctt tcgctcacat ccataatggt agcttctggc ttacgaaaaa
    11281 gggtctctaa gcgattttgc aaaactgcga gtggagttcg taactcatga ctggcatttt
    11341 ccacaaaaga ctgttgcttc tgcatactct caagcagggg cctaacactg accctagcta
    11401 gatagagact ggcaagtaaa gacaaaatcc agaaactagc catcacgacc acaatcaatt
    11461 gctcatgctt ttgactagcc tgctccaact gactggtatt aatcaagaca gcagcatact
    11521 tgatattggt tgaaaccgaa ctaatattgg tctccatcaa aatcacacga tagatttctt
    11581 cctgcccata gctattaaaa acctgaatct ggtagatatg tcctagttct ttcttttcta
    11641 acttaatctt atccaagccc aaaaatcgat ttccagaaag aagttgagta aagtctttat
    11701 caaagagaat gacttccgta ttggaactga cattaggttt tatttctact ttactagcgt
    11761 ccgccctagc attttctaaa tctttaatct cttctgttgc cctatttata gccagctgaa
    11821 taactgcttg aggattttca ctcagtccat gaagcttatc gtccaccgaa gtataaagac
    11881 tcgaatgcat gacttgtaaa ataatcagag tcattgtaga aaaaatcagg gtgaagacac
    11941 cgaagttgcg gataaaataa ctaaagtcat ccgcatacca tgttttttta agtttactga
    12001 acatctttta aaagataccc aacactacgc aaggtttgca aattctctgc aaaagtggtt
    12061 ccctttaatt tcttacggac ttttgaaaca tagacttcga caaccgaaat cgttgtatca
    12121 ctatcaaatc cccatagacg gtcaaaaatc tgcgtcttag gcaaaatcac attttgattt
    12181 tgaaggaaat aaactagtaa atcgaactct ttccccagca attcgacagg agtatcttca
    12241 actttaacgg tattggttga taaattaacc acgatattcc cataagtcaa ggtgttttca
    12301 ttaaacttcc ctgaacgttt gagaagggcc tgaattcgca ttttaagttc ttctaggtag
    12361 aaaggtttgg tcagataatc atccgctccc agttcaaatc catgtccctt gtcatccaaa
    12421 ctttccttgg cagtcataat cagaactggt gtcgtaattc ccttttcacg caattctttt
    12481 aagacttgga aaccattttt ttctggcaac atcaaatcca gcaaaatcaa gtcatagaca
    12541 ccactctcag cttcgtagag accttcttct ccatcaaata cctgcataac atccgcaaaa
    12601 tcgtctaaaa agtcaaatac tgaatttgac agacctaggt catcctcaac caataagatt
    12661 tttatcatga gaaactcctc cttattaaaa ctattatacc aaatttgcct taaaaaaaac
    12721 tcaactctct gcattttaca tgagatagct gagttttctt tggctctata atatttgtag
    12781 tgggtaaatc ccctatggat attatggagc ttatttttgt gtagaaaaaa agtcccatat
    12841 gacctataat gaaaagcgac aaaacaactc attagaaaga atcatatgga acaattacat
    12901 tttatcacaa aactgctcga tattaaagac ccaaacatca agattctaga tatcatcaat
    12961 atggataccc acaaagaaat tatcgctaag ctggattatg aggctccatc ttgccctgat
    13021 tgtggaagtc taatgaagaa atatgacttt caaaaaccgt ctaagatccc ttacctcgaa
    13081 acaactggta tgccttctag aattctcctt agaaaacgcc gtttcaagtg ctatcactgt
    13141 tcaaaaatga tggttgctga gactcccctg gtaaagaaaa atcaccaaat ccctcgtatc
    13201 atcaaccaaa aaatt
//
LOCUS       DAVLCS010000052        12457 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLCS010000052 DAVLCS010000000
VERSION     DAVLCS010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.052"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            185..532
                     /gene="ssrA"
                     /locus_tag="VXC78_001826"
     tmRNA           185..532
                     /gene="ssrA"
                     /locus_tag="VXC78_001826"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(715..802)
                     /locus_tag="VXC78_001827"
     tRNA            complement(715..802)
                     /locus_tag="VXC78_001827"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(766..768),aa:Ser,seq:gga)
     gene            964..1704
                     /locus_tag="VXC78_001828"
     CDS             964..1704
                     /locus_tag="VXC78_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0583849.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            1701..2612
                     /gene="pfkB"
                     /locus_tag="VXC78_001829"
     CDS             1701..2612
                     /gene="pfkB"
                     /locus_tag="VXC78_001829"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV0583850.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            2609..4561
                     /locus_tag="VXC78_001830"
     CDS             2609..4561
                     /locus_tag="VXC78_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0583851.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            4725..6950
                     /locus_tag="VXC78_001831"
     CDS             4725..6950
                     /locus_tag="VXC78_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV0583852.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(7103..7531)
                     /locus_tag="VXC78_001832"
     CDS             complement(7103..7531)
                     /locus_tag="VXC78_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583853.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            7669..8811
                     /locus_tag="VXC78_001833"
     CDS             7669..8811
                     /locus_tag="VXC78_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0583854.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            8820..10034
                     /gene="thiI"
                     /locus_tag="VXC78_001834"
     CDS             8820..10034
                     /gene="thiI"
                     /locus_tag="VXC78_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV0583855.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            10169..10993
                     /locus_tag="VXC78_001835"
     CDS             10169..10993
                     /locus_tag="VXC78_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0583856.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMLYFLGNLYL"
     gene            11006..12172
                     /locus_tag="VXC78_001836"
     CDS             11006..12172
                     /locus_tag="VXC78_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0583857.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
BASE COUNT         3626 a         2398 c         2800 g         3633 t
ORIGIN      
        1 gattgatttt atagttttta aactcaaatg aattgaaata aagagagtac gaaaattctc
       61 atctgaaagt attttagaat aattctcttc gtgaatttct tcaaaacaga tagcttcatc
      121 ttaggtatgt gatttctttt tgcatttttg agttagataa ggtataatgg ttttattgtc
      181 ttttggggtc gttacggatt cgacaggcat tatgaggcat attttgcgac tcgtgtggcg
      241 acgtaaacgc tcagttaaat ataactgcaa aaaataacac ttcttacgct ctagctgcct
      301 aaaaaccagc aggcgtgacc cgatttggat tgctcgtgtt caatgacagg tcttattatt
      361 agcgagatac gattaagcct tgtctagcgg cttgataaga gattgataga ctcgcagttt
      421 ctagacttga gttatgtgtc gaggggctgt taaaataata cataacctat ggttgtagac
      481 aaatatgttg gcaggtgttt ggacgtgggt tcgactccca ccggctccat tattcctttg
      541 cattcttttg cattccttgg taaaacgttg ttaaatcaac gttttttatt tttatctttg
      601 gtattccttt gtattctttt gctaaaaagg gagtcacaaa cagaccctat tttaaaaaaa
      661 ggatagaaaa aaggatacaa catttgtcgc atcctaaaaa taatcttttt tcgacggaag
      721 acatgggatt cgaacccacg cacgctatta cacgcctacc gcgtttccaa cacggcctct
      781 taagcctctt gagtaatctt ccaatactta ctcaaatagt ctaccataaa ggctcttatc
      841 ttgcaataaa aattctagaa ataagaaaaa tgatagattt tgaaagaaaa tgataaaaaa
      901 tgcttgactt cgaaagaaag tatgatagaa tgaatagtgt aaacgataac aggaggtgat
      961 tcagtgttaa aaacagaacg taaacaacta attttagagg agttaaatca gcatcatgta
     1021 gtttctctag aaaaattagt tagtttgcta gaaacgtcag aatcaacggt tcgaagagac
     1081 ttggatgagt tggaagcgga aaacaagctt cgtcgtgtgc atggtggagc agaactcccc
     1141 cactccttac aggaagaaga aaccattcaa gaaaaatctg tcaaaaacct tcaagaaaag
     1201 aagttgctgg ctcagaaagc agcctctctc attaaagaaa aagatgtcat ctttatcgat
     1261 gctggaacaa caactgcttt tttgattcat gaattggtca ataagaatgt tacagttgtg
     1321 accaactcca ttcaccatgc cgctcagttg gttgaaaagc agattccaac tgtcatggtt
     1381 ggaggaaacg tcaagacggc gacagatgct agtatcgggg gcgttgctct taaccagatt
     1441 aaccaattgc actttgaccg tgcctttatc ggaatgaatg gtgttgacga tggctattat
     1501 acgactcctg atatggagga gggagctgtg aaaagagcta ttttggagaa tgccaagcag
     1561 acctacgtct tggtggattc gtcaaaaatt ggacaaactt gctttgccaa ggtagcacca
     1621 ctcaaacgcg ctatcgttat cactagtcaa gggcatgagc tcttgcaggt tattaaggag
     1681 aaaacggagg taatagaagt atgatttata cagtcacact caatccatcc attgactata
     1741 tcgttcgttt ggaccaagtc aaagttggta gtgtaaatcg tatggacagt gatgataagt
     1801 ttgctggtgg gaaaggaatc aatgtcagcc gtgtcttgaa acgtttgaat ataccaaata
     1861 cagcgacggg atttatcggt ggctttactg gtaaatttat cacagatact ttagcagagg
     1921 aagaaatcga gacacgtttt gtccaggtgg cagaagatac tcgtatcaat gttaaaatca
     1981 aagcagacca agaaacagaa atcaacggaa cgggtccaac tgttgaaccg gttcagctag
     2041 aagaattgaa agctatttta tctagtctga cagcagaaga tacagttgtc tttgcaggtt
     2101 caagtgctaa aaatctaggc aatgttatct ataaggattt gatttccttg acgcgccaga
     2161 ctggtgcgca agtggtctgt gactttgaag gacagacctt aattgatagt ttggactacc
     2221 agcctcttct tgtaaaacca aacaatcatg aacttggagc gatttttggg gttaaactcg
     2281 aaagtttaga tgaaattgag aaatacgctc gtgagttact ggctaagggt gctcaaaatg
     2341 ttattatctc tatggctggt gatggcgccc ttcttgtcac atctgaggga gcttacttcg
     2401 ctaaaccaat caaaggaaca gtcaaaaatt cagttggagc tggtgattct atggttgctg
     2461 gattcacagg tgaatttgtc aaatcaaaag acgcagtaga agccttcaaa tggggagtgg
     2521 cttgcggaac ggcaactacc ttctcagatg acttggcaac ggcggaattt attaaagaaa
     2581 catatggaaa agttgaggta gaaaaaagat gaaaattcaa gacctattga gaaaagatgt
     2641 catgttgcta gatttgcagg caactgaaaa aacagctgtc atcgacgaga tgattaaaaa
     2701 tttgacagag cacggttatg taacagattt tgaaacattt aaagaaggaa ttttggcgcg
     2761 tgaagctttg acttctactg gtttgggtga tggaatcgca atgcctcaca gcaaaaacgc
     2821 tgctgtcaaa gaagcgacag ttctatttgc taagtcaaat aagggtgttg actacgagag
     2881 cttggatgga caagcaactg acctcttctt catgattgca gctccagaag gtgccaatga
     2941 tactcacttg gcagccttgg cagaattgtc tcaatacttg atgaaagacg gttttgcaga
     3001 caaacttcgt caagcaacat ctgcagacca agttatcgaa ctttttgacc aagcttcaga
     3061 aaaaactgag gaacttgttc aagcacctgc taatgactct ggtgacttta tcgtagctgt
     3121 tacagcttgt acaacaggta ttgcccacac ttacatggcc caagaagccc ttcaaaaagt
     3181 agctgctgaa atgggggttg gtatcaaggt cgaaaccaac ggtgctagcg gtgttggaaa
     3241 tcaactaact gcagaagata tccgtaaggc taaagctatt atcattgcag cagacaaggc
     3301 cgttgaaatg gatcgatttg atggaaaacc attgatcaat cgtccagttg ctgacggtat
     3361 ccgtaagaca gaagagctaa ttaacttggc tctttcagga gatactgaag tctaccgtgc
     3421 cgctaatggt gccaaagctg caacagcctc taacgaaaaa caaagccttg gtggtgcctt
     3481 gtacaaacac ttgatgagtg gtgtatctca aatgttacca ttcgttatcg gtggtggtat
     3541 catgattgcc cttgccttct tgattgacgg tgctttgggt gttccaaatg aaaaccttgg
     3601 caatcttggt tcttaccatg agttagcttc tatgttcatg aaaattggtg gagctgcctt
     3661 tggtttgatg cttccagtct ttgcgggtta tgttgcctac tctattgctg aaaaaccggg
     3721 tttggtagca ggtttcgtgg ctggtgctat tgccaaagaa ggttttgcct ttggtaaaat
     3781 tccttatgcc gcaggtggtg aagcaacttc aactcttgca ggtgtctcat ctggtttcct
     3841 aggtgccctt gttggtggat ttatcgcagg tgccttggtt cttgccatca agaaatacgt
     3901 taaagttcct cgttcactcg aaggtgctaa atcaatcctt ctattgccac ttcttggaac
     3961 aatcttgaca ggatttgtta tgctagctgt gaatatccca atggctgcaa tcaacactgc
     4021 tatgaatgac ttcctaggcg gtcttggagg aggttcagct gtccttcttg gtatcgtcct
     4081 tggtggaatg atggctgttg acatgggtgg accagttaat aaagcagctt atgtctttgg
     4141 tacaggtacg cttgcagcaa ctgtttcttc aggtggttct gtagccatgg cagcagttat
     4201 ggctggagga atggtgccac cacttgcaat ctttgtcgca actcttcttt tcaaagataa
     4261 atttactaag gaagaacgta actctggttt gacaaacatc atcatgggct tgtcatttat
     4321 cactgaggga gcgattccat ttggtgccgc tgacccagct cgtgcgattc caagcttcat
     4381 ccttggttca gcagtagcag gtggactcgt tggtcttact ggtatcaaac tcatggcgcc
     4441 acacggagga atcttcgtta tcgcccttac ttcaaatgct ctcctttacc tcgtttctgt
     4501 cttggtagga gcaatcgtaa gtggtgtggt ttatggttac ctacgcaaac cacaagcata
     4561 aaaaatagaa aaatgaaaag attggaccgt ttggtgcagt ctttttctct tcccgaaatg
     4621 cctgtgaaat atggtataat agaagaatgg caaacaagaa tacaagtaca acaagacgga
     4681 gaccgtctaa agcagaactg gaaagaaaag aagcgattca acgaatgttg atttcgttag
     4741 gaattgcgat tttattgatt ttcgcagcct tcaaattagg ggctgcaggt ataacccttt
     4801 ataatttaat tcgcttgcta gtgggtagcc tagcttatct ggcgatattc ggcctattaa
     4861 tctatctctt ctttttcaag tggatacgaa aacaggaagg actcttatct ggctttttca
     4921 ccatatttgc tggcttactc ttgatttttg aggcctactt ggtttggaaa tatggtttgg
     4981 acaagtccgt tctaaaaggg accatggctc aggttgtgac agatctgact ggttttcgaa
     5041 cgactagctt tgctggaggg ggcttgatcg gggtcgctct ttatattcca acagcctttc
     5101 tcttttcaaa tatcggaact tactttattg gttctatctt gattttagtg ggttctctcc
     5161 tagtcagccc ttggtctgtt tacgatattg ctgaattttt cagtagaggc tttgccaaat
     5221 ggtgggaagg gcacgagcgt cgaaaagagg aacgctttgt caaacaagaa gaaaaagctc
     5281 gccaaaaggc tgagaaagag gctagattag aacaagaaga gactgaaaaa gccttactcg
     5341 atttgcctcc tgttgatatg gaaacgggtg aaattctgac agaggaagct gttcaaaatc
     5401 ttccacctat tccagaagaa aagtgggtgg aaccagaaat catcctgcct caagctgaac
     5461 ttaaattccc tgaacaggaa gatgactcag atgacgaaga tgttcaggtc gatttttcag
     5521 ccaaagaagc ccttgaatac aaacttccaa gcttacaact ctttgcacca gataaaccaa
     5581 aagatcagtc taaagagaag aaaattgtca gagaaaatat caaaatctta gaagcaacct
     5641 ttgctagctt tggtattaag gtaacagttg aacgggccga aattgggcca tcagtgacca
     5701 agtatgaagt caagccggct gttggtgtaa gggtcaaccg catttccaat ctatcagatg
     5761 acctcgctct agccttggct gccaaagatg tccggattga agcaccaatc cctgggaaat
     5821 ccctaatcgg aattgaagtg cccaactccg atattgccac tgtatctttc cgagaactat
     5881 gggaacaatc gcaaacgaaa gcagaaaatt tcttggaaat tcctttaggg aaggctgtta
     5941 atggaaccgc aagagctttt gacctttcta aaatgcccca cttgctagtt gcaggttcaa
     6001 cgggttcagg gaagtcagta gcagttaacg gcattattgc tagcattctc atgaaggcga
     6061 gaccagatca agttaaattt atgatggtcg atcccaagat ggttgagtta tctgtttaca
     6121 atgatattcc ccacctcttg attccagtcg tgaccaatcc acgcaaagcc agcaaggctc
     6181 tgcaaaaggt tgtggatgaa atggaaaacc gttatgaact ctttgccaag gtgggagttc
     6241 ggaatattgc aggttttaat gccaaggtag aagagttcaa ttcccagtct gagtacaagc
     6301 aaattccgct accattcatt gtcgtgattg tggatgagtt ggctgacctc atgatggtgg
     6361 ccagcaagga agtggaagat gctatcatcc gtcttgggca gaaggcgcgt gctgcaggta
     6421 tccacatgat tcttgcaact cagcgtccat ctgttgatgt catctctggt ttgattaagg
     6481 ccaatgttcc atctcgtgta gcatttgcgg tttcatcagg aacagactcc cgtacgattt
     6541 tggatgaaaa tggagcagaa aaacttcttg gtcgaggaga catgctcttt aaaccgattg
     6601 atgaaaatca tccagttcgt ctccaaggct cctttatctc ggatgacgat gttgagcgca
     6661 ttgtgaactt catcaaggct caggcagatg cagactacga tgagagtttt gatccaggtg
     6721 aggtttctga aaatgaagga gaattttcgg atggagatgc tggtggtgat ccgctttttg
     6781 aagaagctaa gtctttggtt atcgaaacac agaaagccag tgcgtctatg attcagcgtc
     6841 gtttatcagt tggatttaac cgtgcgaccc gtctcatgga agaactggag atagcaggtg
     6901 tcatcggtcc agctgaaggt accaaacctc gaaaagtgtt acaacaataa aaaaatagct
     6961 tctttccgag tttggaggga agctatttta gtggctattg attactttta tactcttcgc
     7021 aaatctcttc aaaccacgtc agcttcgcct tgccgtactc aagtactgtc tacggctagc
     7081 ttcctagttt gctctttgat tttcattgag tattattttc tgaagttgga gtattgggct
     7141 gtttttcatt ttcagtggca ggtttacttg tagcaggtgt agtagagtcc tgagttgctg
     7201 ttttctgatc ttcttttttc tcttccttga cgctagattt tggcgtttct tcttgttgtg
     7261 ttttttcttg agaagtgtta ttttccttat ttggagtagt attttcctga ggggattctt
     7321 tttgaatttc tttgacaaag gttgtcgtct ggcttgtcgt aggttctttt ttagtatttt
     7381 tattattatt atccaaggcg ttcatgatcg tgatacccgc ggtaatcaaa ccaaggatac
     7441 taccgatagt agtaatggtt ttttgaaaaa cagtaaagcc ttttttgata tgttctgttt
     7501 tcggttttga agttctacga tagttagaca tacattctct cctttgatta tgatttatta
     7561 tactctgttt ctttaaaaaa atcttaaaaa aagagaaatt gccctttctt gtcgcaggct
     7621 ccgtttcatg atacaataga aggagtgatt ttagaaagcg tgagaaacat gatttacttt
     7681 gataattcgg cgacgaccag gccctatcca gaagcccttg aaacctatat gcaggtggct
     7741 tcaaaaattt taggaaatcc atctagtctc catcgtttgg gagaccaggc aacacgaatt
     7801 ttagatgctt cccgtcaaca gattgcagat ttaatcggta agaaaagtga tgaaatcttc
     7861 tttacatctg gtgggacaga aggggataac tggatcatca agggagtagc atttgaaaaa
     7921 gcccagtttg gcaagcacat catcgtatca gccattgaac atccagcagt taaggaatca
     7981 gccctctggt tgaaagctca aggttttgaa gtggattttg ctccagttga taacaaagga
     8041 tttgtggatg ttgaggcgct agaagatttg ataagacctg atacgaccct cgtttccatc
     8101 atggctgtga acaatgaaat cggctctatc caacctattg aggctatttc agaattcttg
     8161 gcagacaagc caactatttc cttccacgtt gatgcggttc aggcgcttgc caagattccg
     8221 actgaaaagt atctgacaga acgagtggat ttcgcgactt tctctggtca caagttccac
     8281 ggaatccgtg gtgttggttt tatctatatc aagtctggca agaagattac gcctctttta
     8341 acaggtggtg gtcaggaacg tgattaccgt tcgacaactg aaaatgtggc aggaattgca
     8401 gcgaccgcta aggctctccg tttatctatg gaaaagctag atatctttag gagcaagact
     8461 gggcagatga aggcagtgat tcgtcaagca cttctggact atccggatat atttgtcttt
     8521 tcagatgagg aagacttcgc ccctcatatt ctgacttttg gaatcaaggg tgttcgtggt
     8581 gaggtcattg ttcacgcctt tgaagactat gatattttca tctcaacgac ctcggcttgt
     8641 tcgtccaagg ctgggaaacc agccggaacc ctgattgcta tgggagtgga caaggataag
     8701 gctcagtcag ctgtgcgtct tagtctagac cttgaaaatg atatgagtca ggtcgagcag
     8761 ttcttgacca agctaaaatt aatttacaat caaactagaa aagtaagata ggagcattca
     8821 tgcagtattc agaaattatg attcgctacg gtgagctgtc aaccaagggc aaaaatcgta
     8881 tgcgtttcat caataaactt cgcaataata tttcagacgt tttgtctatc tatccccaag
     8941 ttaaggtaac agcagatcgc gaccgtgccc acgcttacct caatggagca gattacacag
     9001 cagtagcaga atcgctcaaa caagtatttg gaattcaaaa cttttcccct gtttataagg
     9061 ttgaaaaatc tgtagaagtt ctgaagtctg ctgtccaaga gattatgcag gacatctaca
     9121 aggaaggcat gacctttaaa atctctagca agcgtagcga ccacaccttt gaattggaca
     9181 gtcgtgaact caaccaaacg cttggagggg ctgtattcga agccattcca aacgtacaag
     9241 ctcaaatgaa aagtcctgac atcaatcttc aggtggagat acgtgaagaa gcagcctatc
     9301 tttcttatga aaccgttcga ggggcaggtg gattaccagt gggaacttct ggtaagggca
     9361 tgctcatgtt gtcaggggga atcgattccc ctgtagctgg ctatctagcg cttaaacgag
     9421 gggtagatat agaggcagtt cactttgcca gcccacctta cacgagtcct ggtgctctta
     9481 aaaaagccca agatttgacc cgtaaattaa ccaaatttgg gggaaatatc cagtttatcg
     9541 aagttccttt tacagagatt caagaggaaa tcaaagccaa agcgccagaa gcctacctta
     9601 tgaccttgac gcgtcgtttt atgatgcgta ttacggaccg tattcgtgag gtacgaaatg
     9661 gtttagttat catcaatggg gaaagtctag gtcaagtagc cagccaaacc cttgaaagta
     9721 tgaaggctat caatgctgtt accaacactc ccatcattcg tcctgtggtt accatggaca
     9781 agttggaaat cattgacatc gcccaggaaa tcgatacctt tgacatttca atccaaccgt
     9841 ttgaagactg ttgtactatt tttgcaccag atcgtccaaa aacaaatcct aaaattaaga
     9901 atgcggagca gtacgaagcg cgtatggatg ttgaaggctt ggttgagcga gcagtggctg
     9961 gaatcatgat tactgaaatc acacctcaag ccgaaaaaga tgaagttgat gacttgattg
    10021 acaatctgct ctaattcaga aaatccaaaa gaatagcgaa aatcagtaaa aaaagttagt
    10081 tttttctcta aaaacaggta aaaaactaac tttttttatt tttatgatat aatgatataa
    10141 aattttgaat atagagagtt ttctgacaat taatcaatcc tacttttatc taaaaatgaa
    10201 agaacacaaa ctcaaagttc cttatacagg taaggagcgc cgtgtacgta ttcttcttcc
    10261 taaagattat gagaaagata cagaccgttc ctatcctgtt gtatactttc atgacgggca
    10321 aaatgttttt aatagcaaag agtctttcat tggacattca tggaagatta tcccagctat
    10381 caaacgaaat ccggatatca gtcgcatgat tgtcgttgct attgacaatg atggtatggg
    10441 gcggatgaat gagtatgcgg cttggaagtt ccaagaatct cctatcccag agcagcagtt
    10501 tggtggtaag ggtgtggagt atgctgagtt tgtcatggag gtggtcaagc cttttatcaa
    10561 gcacaaaaca ggttggtttg atggcatgat gacgacaggt tgctctatgg gagcctatca
    10621 tgcactcaat ttcttcctcc agcatccaga tgtctttacc aaagtgattg ctctcagtgg
    10681 tgtttacgac gcacgtttct ttgtcggcga ttactacaac gatgatgcta tttaccaaaa
    10741 ctcgccagta gattatattt ggaaccaaaa cgatggctgg tttattgacc gttaccgtca
    10801 ggcagagatt gtgctgtgta cggggcttgg agcctgggaa caagatggtt taccatcctt
    10861 ttacaagctc aaagaagcct ttgaccagaa acaaattcca gcctggtttg ctgaatgggg
    10921 acatgatgtc gcccacgact gggaatggtg gcgtaaacaa atgctttatt tcctcggtaa
    10981 tctctattta taaaaggagt tacctatgaa ttaccttgtt atttctccct actatccaca
    11041 aaactttcaa cagtttacca tcgaactagc taataaaggc atcacagtct tgggaattgg
    11101 tcaagagtct tacgagcaat tggatgagcc cttgcgcaat agcttgaccg agtattttcg
    11161 tgttgataat cttgagaaca tagatgaagt caaacgtgca gttgcttttc tcttttataa
    11221 acatggtcca attgaccgca tcgagtctca caatgaatac tggcttgagc tagacgcaac
    11281 actcagagaa caattcaatg tttttggtgc caaaccagag gatctcaaaa agacgaaata
    11341 taagtctgaa atgaagaaac ttttcaaaaa agcaggtgtt cctgtggtac ctggagctgt
    11401 tatcaagacg gaagcagatg ttgatcaagc agtgaaagaa atcggtcttc caatgattgc
    11461 caaacctgat aatggagtgg gagcagccgc aacctttaaa cttgagacag aagacgatat
    11521 caatcacttc aagcaagaat gggaccattc aaccctttat ttctttgaaa aatttgtcac
    11581 ttccagcgaa atctgtacct ttgacgggct cgtggacaag gatggaaaga ttgtcttctc
    11641 aacaaccttt gactacgcct atacaccgct tgacctcatg atttataaga tggacaattc
    11701 ttattatgtg ctcaaggata tggatcctaa actgcgcaag tatggggaag caattgtcaa
    11761 agaatttggt atgaaagaac ggtttttcca tattgagttc ttccgtgagg gggacgatta
    11821 tattaccatc gagtacaata accgccctgc aggtggtttt accattgatg tttataactt
    11881 tgctcattcc ttggaccttt atcgtggcta tgcagctatt gtcgcaggag aggagttccc
    11941 ggcgtcagac tttgaaactc agtattgttt ggctacttct cgccgtgcaa atgctcacta
    12001 tgtttattca gaagaggatt tgcttgccaa atatagccag cagttcaagg ttaaaaaagt
    12061 catgccagct gccttcgcgg aacttcaagg agattacctg tatatgctga caactccgag
    12121 tcgacaagaa atggatcaga tgattgctga tttcggacaa cgtcaagaat aagaactatc
    12181 ggattaagga aattcactcc cttaatcctt ttgttttgtc tggtaaaaaa taagagcatc
    12241 ctaacaaggt agctatcata aaacttgttc gataactatt tgaagcagga ttaggtggct
    12301 agaaattgaa ttttaacatt tcaatttagt catagtattg tgttttcgta tccttaaatc
    12361 agctaaaagg atccatgacg acacctatac gatatagttt tcaggatacc aaaccagtct
    12421 attaatactc aatgaaaatc aaagagcaaa ctaggaa
//
LOCUS       DAVLCS010000053        12012 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLCS010000053 DAVLCS010000000
VERSION     DAVLCS010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.053"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(169..1800)
                     /locus_tag="VXC78_001837"
     CDS             complement(169..1800)
                     /locus_tag="VXC78_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV0583858.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLHQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2089..7029
                     /locus_tag="VXC78_001838"
                     /pseudo
     CDS             2089..7029
                     /locus_tag="VXC78_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
     gene            7119..8315
                     /locus_tag="VXC78_001839"
     CDS             7119..8315
                     /locus_tag="VXC78_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV0583859.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8451..8978
                     /locus_tag="VXC78_001840"
     CDS             8451..8978
                     /locus_tag="VXC78_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0583860.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9055..9411
                     /gene="glnR"
                     /locus_tag="VXC78_001841"
     CDS             9055..9411
                     /gene="glnR"
                     /locus_tag="VXC78_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV0583861.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9448..10794
                     /gene="glnA"
                     /locus_tag="VXC78_001842"
     CDS             9448..10794
                     /gene="glnA"
                     /locus_tag="VXC78_001842"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV0583862.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLELY"
     gene            complement(10890..11009)
                     /locus_tag="VXC78_001843"
     CDS             complement(10890..11009)
                     /locus_tag="VXC78_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV0583863.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11267..11404
                     /locus_tag="VXC78_001844"
     CDS             11267..11404
                     /locus_tag="VXC78_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583864.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEDLNIRLEVK
                     N"
     gene            11497..12012
                     /locus_tag="VXC78_001845"
                     /pseudo
     CDS             11497..12012
                     /locus_tag="VXC78_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3864 a         2189 c         2571 g         3388 t
ORIGIN      
        1 gatcaggaca gtcaaatcga tttctaacaa tgttttagaa atagaggtgt actattctag
       61 tttcaatata ctatatatct gcagaatact ctttcagttt cattcagcct agtcttgctt
      121 aggaaaaagt aaaaagccat ccaattatga tggatagctt cttggttctt agatttgttc
      181 tgcaaaaacc ttttcagcaa ggttcatagc gtggtctgat acacgagtgt agtgtgagat
      241 gatgtcgata aagttgaccc cagcttgtgt tgaacattcg cctttgttga ggcgtttgat
      301 gtgggttttt ctgagaacac gttctatctt attgattgct tcatgacgtt ctacaagact
      361 gcgtgctttt tcaatatcat tgttttccac actatccaga gcatctttga taaagtcact
      421 agtttggcgg taaacttcct ctaattcttt caaggcggca tcagaaaatt caacattttt
      481 ccgttgaaga tagtcagtca gattgagtag agcctccgtg tggtctccaa tccgttccaa
      541 atcacgggag gaatcaagga tattggtaag cacttcactt tctttttggc tgagagcttc
      601 gcttgaaagg gcaatgagat aacgtgttaa ttgctcatcg atggtgttaa ttgcttcttc
      661 ggttttatgc cctttttcag caactttttc atccaagtca atgatgtact tataggaaag
      721 gtcaaaggct ttagcagcgt agtttcctaa gtgcaagagc tctttcttag catttcctag
      781 agcgatagat ggggcctgtt tgatgaaatg ttcatcaaga tataagggtt cgtatttgac
      841 aacctcgtcc tctccaggaa taatcttggt tacaaagtaa gccagagctc cgataaatgg
      901 aaattggaca atggtgttgg taatattaaa ggttccgtga gcaaaggcga tggtcatttc
      961 cggtgctaga tttagcgtag cttcaaacca atgaatcagg acagtaaaag gaactagaaa
     1021 aataacgcag acgactgttc cgataacgtt gaaggcaaca tgagctcctg ctacccgttt
     1081 agctgcaata ttagccccta aagaggcaat gatggctgta atggttgtcc cgatattgtc
     1141 accaaataga accggcaaag ctccctgtag gtcaattaga ttgccggcgt agaggttttg
     1201 taaaatccca atggtagccg aagaagcttg aattagcaag gtcaagccag taccgacaaa
     1261 gacacccaaa acaggatttt tacttagctc aatcatatag tccttaaaga cctgtaaatc
     1321 cttgagtgga gccattgcgc cgctcatgag attgagggca aaaaagatac caccgacacc
     1381 aaagaggatg cgtccgatat tattgactgt ccgatttttt gtaaaaaaga gacagacggc
     1441 accgataaag agcataggta gggcatagtt acctaattta aaaccgatga gaaaggatgt
     1501 gacagttgtc ccaatattag cacccatgac aatcccgata gcctgatgta aggttaagag
     1561 accggcactg accaggccga ctgtgataac tgttacacca gaactagact gaattagagc
     1621 agtcatccca ataccaacca gaactccaaa gaaaggatta ctagtatatt tgtcaatgta
     1681 aaaacgaagg cgatctccag cagcttgttg taaaccgtct cccatggtct tgatactata
     1741 taagaatagc cccagaccac ctaaaaagtg aaataaaatt tcctgccaat taatggacat
     1801 ttctttttcc tccgaaaaat aatcgcggaa tatctcctat tctattttaa aggataaaag
     1861 taaatctaac aagtgttaat gtcaagtttg taaaagaaaa ttataattga taagtgtatt
     1921 atttttaaga gtttttaacc ttattttaga tttgtgaaaa cagctattgt tttttgtcta
     1981 aaaatgtttt aggataaaaa tgtgattatc atgattctag agttaaaaaa ctacagaata
     2041 taaagcgctt tcttgaaaac aacaaaatca atcttttagg aggagaaaat gaagaatcca
     2101 ttttttgaaa gacgttgtcg ttacagtatt cgtaagttat cagtaggagc ctgctcgctg
     2161 atgattggtg ctgttttatt tgctggtcca gccttggctg aagaaactgc agttcctgaa
     2221 aatagcggag ctaatacaga gcttgtttca ggagagagtg agcattcgac caatgaagct
     2281 gataagcaga atgaagggga acatactaga gaaaacaagc tagaaaaggc agaaggagta
     2341 gcgacagcat ctgaaactgc agaagcagct agcgcagcta aaccagagga aaaagcaagt
     2401 gaggtggttg cagaaacacc atctgcagaa gcaaaaccta agtctgacaa ggaaacagaa
     2461 gcaaagcccg aagcaactaa ccaaggggat gagtctaagc cagcagccga agctaataag
     2521 actgaaaaag aagtccagcc agatgtccct aaaaatacag aaaaaacatt aaaaccaaag
     2581 gaaatcaaat ttaattcttg ggaagaattg ttaaaatggg aaccaggtgc tcgtgaagat
     2641 gatgctatta accgcggatc tgttgtcctc gcttcacgtc ggacaggtca tttagtcaat
     2701 gaaaaagcta gcaaggaagc aaaagttcaa gccttatcaa acaccaattc taaagcaaaa
     2761 gaccatgctt ctgttggtgg agaagagttc aaggcctatg cttttgacta ttggcaatat
     2821 ctagattcaa tggtcttctg ggaaggtctc gtaccaactc ctgacgttat tgatgcaggt
     2881 caccgtaacg gggttcctgt atacggtaca ctcttcttca actggtctaa tagtattgca
     2941 gatcaagaaa gatttgctga agctttgaag caagacgcag atggtagctt cccaattgcc
     3001 cgtaaattgg tagacatggc caagtattat ggctatgatg gctatttcat caaccaagaa
     3061 acaactggag atttggttaa acctcttgga gaaaagatgc gccagtttat gctctatagc
     3121 aaggaatatg ctgctaaggt aaaccatcca atcaagtatt cttggtatga tgccatgacc
     3181 tataactatg gacgttacca tcaagatggt ttgggagaat acaactacca attcatgcaa
     3241 ccagaaggag ataaggttcc ggcagataac ttctttgcta actttaactg ggataaggct
     3301 aaaaatgatt acactattgc aactgccaac tggattggtc gtaatcctta tgatgtattt
     3361 gcaggtttgg aattgcaaca gggtggttcc tacaagacaa aggttaagtg gaatgacatt
     3421 ttagacgaaa atgggaaatt gcgcctttct cttggtttat ttgccccaga taccattaca
     3481 agtttaggaa aaactggtga agattatcat aaaaatgaag atatcttctt tacaggttat
     3541 caaggagacc ccactggcca aaaaccaggt gacaaagatt ggtatggtat tgctaaccta
     3601 gttgcggacc gtacgccagc ggtaggtaat acttttacta cttcttttaa tacaggtcat
     3661 ggtaaaaaat ggttcgtaga tggtaaggtt tctaaggatt ctgagtggaa ttatcgttca
     3721 gtatcaggtg ttcttccaac atggcgctgg tggcagactt caacagggga aaaacttcgt
     3781 gcagaatatg attttacaga tgcctataat ggcggaaatt cccttaaatt ctctggtgat
     3841 gtagctggta agacagatca ggatgtgaga ctttattcta ctaagttaga agtaactgag
     3901 aagaccaaac ttcgtgttgc ccacaaggga ggaaaaggtt ctaaagttta tatggcattc
     3961 tctacaactc cagactacaa attcgatgat gcagatgcat ggaaagagct aaccctttct
     4021 gacaactgga caaatgaaga atttgatctc agctaactag caggtaaaac catctatgca
     4081 gtcaaactat ttttcgagca tgaaggtgct gtaaaagatt atcagttcaa cctaggacaa
     4141 ttaactatct cggacaatca ccaagagcca caatcgccga caagcttttc tgtagtgaaa
     4201 caatctctta aaaatgccca agaagcggaa gcagttgtgc aatttaaagg caacaaggat
     4261 gcagatttct atgaagttta tgaaaaagat ggagacagct ggaaattact aactggctca
     4321 tcttctacaa ctatttatct accaaaagtt agccgctcag caagtgctca gggtacaact
     4381 caagaactga aggttgtagc agtcggtaaa aatggagttc gttcagaagc tgcaaccaca
     4441 acctttgatt ggggtatgac tgtaaaagat accagcctac caaaaccact agctgaaaat
     4501 atcgttccag gtgcaacagt tattgatagt actttcccta agactgaagg tggagaaggt
     4561 attgaaggta tgttgaacgg taccattact agcttgtcag ataaatggtc ttcagctcag
     4621 ttgagtggta gtgtggatat tcgtttgacc aagccacgta ccgttgttag atgggtcatg
     4681 gatcatgcag gagctggtgg tgagtctgtt aacgatggct tgatgaacac taaagacttt
     4741 gacctttatt ataaagatgc agatggtgag tggaagctag ctaaggaagt ccgtggtaac
     4801 aaagcacacg tgacagatat cactcttgat aaaccaatca ctgctcagga ctggcgcttg
     4861 aatgttgtca cttctgacaa tggaactcca tggaaggcta ttcgtatcta taactggaaa
     4921 atgtatgaaa agcttgatac tgagagtgtc aatattccga tggccaaggc tgcagcccgt
     4981 tctctaggca ataacaaggt acaagttggc tttgcagatg taccggctgg agcaactatt
     5041 accgtttatg ataatccaaa ttctcaaact ccgctcgcaa ccttgaagag cgaagttgga
     5101 ggagacctag caagtgcacc attggatttg acaaatcaat ctggtcttct ttattatcgt
     5161 acccagttgc caggcaagga aattagtaat gtcctagcag tttccgttcc aaaagatgac
     5221 agaagaatca agtcagtcag cctagaaaca ggacctaaga aaacaagcta cgccgaaggg
     5281 gaggatttgg accttagagg tggtgttctt cgagttcagt atgaaggagg aactgaggac
     5341 gaactcattc gcctaactca cgcaggtgta tcagtatcag gttttgatac gcatcataag
     5401 ggagaacaga atcttactct ccaatatttg ggacaaccag taaatgctaa tttgtcagtg
     5461 actgtcactg gccaagatga agcaagtccg aaaactattt tgggaattga agtaagtcag
     5521 gaaccgaaaa aagattacct agttggtgat agcttagact tgtctgaagg acgctttgca
     5581 gtggcttata gcaatgacac catggaagaa cattccttta ctgatgaggg agttgaaatt
     5641 tctggttacg atgctcaaaa gactggtcgt caaaccttga cgcttcgtta ccaaggtcat
     5701 gaagtcaact ttgatgtttt ggtatctcca aaagcagcat tgaacgatga gtacctcaaa
     5761 caaaaattag cagaagttga agctgctaag aacaaggtgg tctataactt tgcttcacca
     5821 gaagtaaaag aagctttctt gaaagcaatt gaagcggccg aacaagtgtt gaaagaccat
     5881 gaaactagca cccaagatca agtcaatgac cgacttaata aattgacaga agctcataaa
     5941 gctctgaatg gtcaagagaa atttacggaa gaaaagacag agcttgatcg cttaacaggt
     6001 gaggctcaag aactcttggc tgccaaacca aaccatcctt caggttctgc cctagctccg
     6061 cttcttgaga aaaacaaggc cttggttgaa aaagtagatt tgagtccaga agagcttgca
     6121 acagcgaaac agagtctaaa atatctggtt gctttattga aagaagacaa gtcagcagtc
     6181 ttttctgata gtaaaacagg tgttgaagta cacttctcaa ataaagagaa gactgtcatc
     6241 aagggtttga aagtagagcg tgttcaagca agtgctgaag agaagaaata ctttgctgga
     6301 gaagatgctc atgtctttga aatagaaggt ttggatgaaa aaggtcaaga tgttgatctc
     6361 tcttatgctt ctattgtgaa aatcccaatt gaaaaagata agaaagttaa gaaagtattt
     6421 ttcttacctg aaggcaaaga ggcagtagaa ttgacttttg aacaaacgga tagtcatgtt
     6481 atctttacag catctcactt tactcattat gcctttgttt atgaatctgc tgaaaaacca
     6541 caacctgcta aaccagcacc acaaaacaca gtccttccaa aacctactta tcaaccggct
     6601 tctgatcaac aaaaggctcc taaattggaa gttcaagagg aaaaggttgc ctttcatcgt
     6661 caagagcatg aaaatgctga gatgctagtt ggggaacaac gagtcatcat acagggacga
     6721 gatggactgt taagacatgt ctttgaagtt gatgaaaacg gtcagcgtcg tcttcgttca
     6781 acagaagtca tccaagaagc gattccagaa attgttgaaa ttggaacaaa agtaaaaaca
     6841 gtaccagcag tagtagctac acaggaaaaa ccagctcaaa atacagcagt taaatcagaa
     6901 gaagcaagca aacaattgcc aaatacagga acagctgatg ctaatgaagc cctaatagca
     6961 ggcttagcca gccttggtct tgctagttta gccttgacct tgagacggaa aagagaagat
     7021 aaagattaaa tatcgaaaaa tcttgtgaaa tctttcctta tatttccaaa gtgtgatata
     7081 atagtttcga ataaaataaa taaaggagtt tttgtaacat ggcaaaactt actgttaaag
     7141 acgttgactt gaaaggtaaa aaagtcctcg ttcgtgttga cttcaacgta ccattgaaag
     7201 atggcgtaat cactaacgat aaccgtatca cagcagctct tccaactatt aagtacatca
     7261 tcgaacaagg tggacgtgca attcttttct ctcaccttgg acgtgtgaaa gaagaagctg
     7321 ataaagctgg taaatcactt gctcctgtag cagctgactt ggcagcaaaa cttggtcaag
     7381 atgttgtttt cccaggtgtc actcgtggtg ctgaattgga agcggcaatc aacgctcttg
     7441 aagatggaca agttctcttg gttgaaaaca ctcgttacga agatgttgac ggcaagaaag
     7501 aatctaaaaa cgatcctgaa cttggtaaat actgggcatc acttggagat ggtatcttcg
     7561 taaacgatgc attcggtaca gctcaccgtg cacacgcatc taacgttggt atctcagcaa
     7621 acgttgaaaa agcagttgct ggtttccttc ttgaaaacga aattgcctac atccaagaag
     7681 cagttgaaac tccagaacgt ccattcgtgg ctatccttgg tggttcaaaa gtttcagaca
     7741 agatcggtgt tatcgaaaac ttgcttgaaa aagctgataa agtccttatc ggtggtggga
     7801 tgacttacac attctacaaa gcacaaggta tcgaaatcgg taactcactt gtagaagaag
     7861 acaaattgga tgttgcgaaa gctcttcttg aaaaagcaaa tggtaaattg atcttgccag
     7921 ttgactcaaa agaagctaac gcatttgctg gttacactga agtgcgtgac actgaaggtg
     7981 aagcagtttc tgaaggcttc cttggtcttg acatcggtcc aaaatctatc gccaaatttg
     8041 acgaagcttt gactggtgcc aaaacagttg tatggaacgg acctatgggt gtatttgaaa
     8101 acccagattt ccaagctggt acaatcggtg tgatggacgc tatcgtgaaa caaccaggag
     8161 ttaaatcaat catcggtggt ggtgactcag ctgccgcagc gattaacctt ggccgtgcag
     8221 acaagttctc atggattagt acgggtggtg gagcatcaat ggaacttctt gaaggtaagg
     8281 ttcttccagg acttgcagcc ctgacagaaa aataagattt tataaacaaa tcaaagaaga
     8341 gagggatgaa agttcctctt ttcttttgct taaaataaaa acgcttcctc tcaactatta
     8401 ctcataaaaa tcaccgattt atgataaaat ggaaatagaa agttgagatt atgagttatt
     8461 ttaaaaaata taaattcgat aaatcccagt tcaaacttgg tatgcgaacc tttaaaacag
     8521 gtattgctgt ttttctagtt ctcttgattt ttggcttttt tggctggaaa ggtcttcaaa
     8581 ttggtgcttt gacagccgtt tttagcctga gggagagttt tgatgagagt gttcattttg
     8641 ggacttcgcg tattctagga aatagtatcg gtggactcta tgccttggtc tttttcttat
     8701 taaatacctt tttccacgaa gccttttggg tgaccttggt agttgttcca atctgcacca
     8761 tgttaaccat tatgacaaat gtagccatga ataacaaagc aggggttatt ggtggtgtag
     8821 cagctatgtt aatcattacc ctatcaattc caagtggtga gacaattttg tacgtgtttg
     8881 tgcgtgtatt agaaacgttt atgggagttt ttgtcgcaat tatcgtaaat tacgatattg
     8941 atcgtattcg tctcttttta gagaaaaaag aaaaataatg ttacatttta taacattatc
     9001 aattgacgtt tgtctttttt tagactataa tagacagaaa gaaggaaatt gtaaatgaag
     9061 gaaaaagaat ttcgccgaaa tatggctgtt tttcctatcg gcagtgttat gaagttgacc
     9121 gatttatcgg cgcgtcagat tcgttattat gaagatcaag agttgatcaa gcccgatcga
     9181 aacgaaggaa atcgtcgcat gtattccttg aatgacatgg atcgtctgct tgaaatcaaa
     9241 gattatatct ctgaaggtta taatatcgct gccattaaga aaaaatatgc tgaacgtgaa
     9301 gcgaaatcca agaaagcggt tagtcagact gaagtacgtc gtgcacttca caatgaactc
     9361 ctccaacagg ggcgttttgc ttcagtacag tcaccttttg gtcgcggtta ggcaaccgca
     9421 agtagtcata gattaaggag aaaacttatg ccaatcacag ctgcagatat tcgtcgtgaa
     9481 gtcaaggaaa aaaatgttac ctttattcgt cttatgttct cagatatttt gggaaccatg
     9541 aaaaacgtcg aaattcctgc tacagatgaa cagttagata aggtcttgtc gaacaaggtt
     9601 atgtttgatg gatcttctat tgaaggtttt gtacgtatca atgagtcgga tatgtacttg
     9661 tacccggact tggatacatg gacagtcttc ccttggggag atgaaaatgg aagtgttgca
     9721 ggtctgatct gtgatgtcta tacaacagaa ggtgaaccat ttgcgggtga ccctcgtggt
     9781 aatttgaaac gagctcttcg tcacatggaa gaagttggat tcaaatcctt caaccttggt
     9841 ccagagccag aattcttcct atttaagttg gatgaaaatg gggacccaac acttgaagtg
     9901 aatgacaagg gtggctactt tgatttggca cctactgacc ttgcggacaa cacacgtcgt
     9961 gagattgtga atgtcttgac caaaatggga tttgaagtag aagcgagtca ccacgaggtt
    10021 gcggttggac agcatgagat tgactttaag tacgatgaag ttctccgtgc ttgtgataag
    10081 attcaaatct ttaaacttgt tgttaaaacc attgctcgca aacacggact ttacgcaaca
    10141 tttatggcga agccaaaatt tggtattgct ggatcaggta tgcactgtaa tatgtccttg
    10201 tttgatgcag aaggaaataa cgccttcttt gatccaaatg atccaaaagg aatgcagttg
    10261 tcagaaacag cttaccattt cctaggcggt ttgatcaagc atgcttacaa ctatactgcc
    10321 atcatgaacc caacagttaa ctcatacaaa cgtttggttc caggttatga agcgcctgtt
    10381 tacattgctt gggctggtcg taaccgttcg ccacttgtgc gcgtacctgc ttcacgtggt
    10441 atgggaactc gtcttgagtt gcgttcagtg gatccaatgg cgaaccctta cgttgctatg
    10501 gctgttcttt tggaagttgg tttgtatggt attgaaaata aaatcgaagc accagctcct
    10561 atcgaagaaa atatctacat catgacagca gaagagcgca aggaagctgg tattacagac
    10621 cttccatcaa ctcttcacaa cgctttgaaa gctttgacag aagatgaagt ggttaaagct
    10681 gctctcggag atcacatcta cactagcttc cttgaagcca aacgaatcga atgggcaagt
    10741 tatgcaacct tcgtttcaca atgggaaatt gataattatt tagagcttta ctaatactaa
    10801 tatagaagaa agattgcctg tgggtaaaca gtcacacagc agtctaagcc atcaaatacc
    10861 tataaccctt aaaatagcga tttcggtcgc tatttatttt tcgaaaaatc ctcttgactc
    10921 ttttgcgaat tagatttatc atcagacgtg tagaagaaaa ttaaggagtc actatggaaa
    10981 aattcaattt caaaaacaat atcgggcaag aaaacaagtt acttcaaatc gaaatctaca
    11041 agtttactaa cttttgcaag cttcaaaatt acacatctgt aaatattttt tcgaaagata
    11101 tatttgaaac catagtaaat tgagactaga atagtacact acatctgcta aaaatttcta
    11161 gaaactaatt taactttcct aatcgatttg tttacatctt atttcaatct actatattat
    11221 ctcaataaat gatgatggcg actgttttgt ttgtgcttgt cgatttttga atcctgatcg
    11281 agcggaagaa tatttctgcc gaggttgcca aggggaaaat cctgaagata ttgaatttta
    11341 tgatgaacaa ttacaggcag aaaaggtgga ggatttgaat attcgattgg aagtaaaaaa
    11401 ttgaattatc tacaatctca tcaacaataa acctatttca accccattat ctataggcgt
    11461 atttttacgc ctttttatat acttgaagca cataagaaac attatgggaa gtttgctgat
    11521 ggaagtactc aagaaattga tgttccttat gatattcctg atacttggga gtgggtgagg
    11581 ataaaatcaa tttattggaa ttttgggcaa aataagccag agaaatcctt taggtatata
    11641 gatacgtcta gtattgatag aaaaaagaac ataatcaact acaaaaatct acaatatctt
    11701 tcacctgaac aagcgccttc ccgtgctaga aaattagttt cgcagaatag tgtcttattt
    11761 tcaacagtta gaccatatct aaaaaatatt gctgtagtta gagaacttaa agagtatttg
    11821 atagctagta cagcatttat tgttttggat actttactta acgaaacata tttgaaatat
    11881 tatttattat cagataattt tatcaatcgt gttaataata aatctactgg aacaagttat
    11941 cctgcaatca atgattataa ttttaatcta ttattaattg ctctcccccc actatccgaa
    12001 caacaacgaa ta
//
LOCUS       DAVLCS010000054        11795 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLCS010000054 DAVLCS010000000
VERSION     DAVLCS010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11795
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.054"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            13..1014
                     /locus_tag="VXC78_001846"
     CDS             13..1014
                     /locus_tag="VXC78_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0583865.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            1622..1699
                     /locus_tag="VXC78_001847"
                     /pseudo
     CDS             1622..1699
                     /locus_tag="VXC78_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2155..3516
                     /gene="trpE"
                     /locus_tag="VXC78_001848"
     CDS             2155..3516
                     /gene="trpE"
                     /locus_tag="VXC78_001848"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV0583866.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3513..4079
                     /locus_tag="VXC78_001849"
     CDS             3513..4079
                     /locus_tag="VXC78_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV0583867.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            4090..5094
                     /gene="trpD"
                     /locus_tag="VXC78_001850"
     CDS             4090..5094
                     /gene="trpD"
                     /locus_tag="VXC78_001850"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV0583868.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5091..5858
                     /gene="trpC"
                     /locus_tag="VXC78_001851"
     CDS             5091..5858
                     /gene="trpC"
                     /locus_tag="VXC78_001851"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV0583869.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            5845..6444
                     /locus_tag="VXC78_001852"
     CDS             5845..6444
                     /locus_tag="VXC78_001852"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV0583870.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGEGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLPQSFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            6422..7645
                     /gene="trpB"
                     /locus_tag="VXC78_001853"
     CDS             6422..7645
                     /gene="trpB"
                     /locus_tag="VXC78_001853"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0583871.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            7638..8414
                     /locus_tag="VXC78_001854"
     CDS             7638..8414
                     /locus_tag="VXC78_001854"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV0583872.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLANTDIALIPLVSLTTGI
                     ERQKELIAGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(8386..8487)
                     /locus_tag="VXC78_001855"
                     /pseudo
     CDS             complement(8386..8487)
                     /locus_tag="VXC78_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            8716..9447
                     /locus_tag="VXC78_001856"
     CDS             8716..9447
                     /locus_tag="VXC78_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583873.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            9462..10613
                     /locus_tag="VXC78_001857"
     CDS             9462..10613
                     /locus_tag="VXC78_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0583874.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRASNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSICLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(10665..11324)
                     /locus_tag="VXC78_001858"
     CDS             complement(10665..11324)
                     /locus_tag="VXC78_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV0583875.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            11394..>11795
                     /locus_tag="VXC78_001859"
     CDS             11394..>11795
                     /locus_tag="VXC78_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0583876.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQM"
BASE COUNT         3721 a         2074 c         2718 g         3282 t
ORIGIN      
        1 tagaggactg aaatgaaaaa tataaatggg aaaaaggtaa ctatttatga tattgcacgt
       61 ttatcaggtt tttctccaaa aacagtttca cgagttatta atggtggagt aaatgttaaa
      121 gaagaaactt atcaagcgat tcaaaaagtt atagaggaat tgtcgtatat tccaaatgcg
      181 tatgcaaaaa atttaactaa aaaagaagct ataaatatat tgatttctgt aaaaaaaatc
      241 gactcttttc ctttaatttg gtttcatacg ctgttagata aagtgttacg gacgtgtaaa
      301 gaatttggtg ttaatgctat agttgagtac tttggagagg aggatacaat tagtaattca
      361 attatatcaa gcacaggtag cctagtagat ggtgttattg ttttttatga aagtgtagat
      421 gatatcagaa ttcagtattt aaagaagaac catatgcctt ttcttgtttt cggtgaatct
      481 caaacgtctg gagtagtcta tgtatctaat aataattttc aagctactta tgatatgatg
      541 aaagctgtaa ctgaagaaaa atttaaaaat atgtggttgc ttatgggagg agaatctcat
      601 gttaataagg atcgtgaaag aggtgtgcgt tcttttctga atgataaaaa ttactttatg
      661 gatttaaaag tcatttatgg cttatctaca attgattcag tttattctta tgcaatgcag
      721 cacttgacta cccaaaatta tccggacatt atttttgttt caggagatga aaaggttcag
      781 ggcttgattc gtgcgtgcta tgagaaagga attcttattc cagatgatat ttctattatt
      841 ggatttgata atattcctat ttctcagtat tatactccag ctttgtctac aattgctccc
      901 aattatgtta aattggctaa agaaatgata gaaggtgttt tagcaattat taaaggggaa
      961 agtgtcacat ctgttgaagt ttctcctaaa tttgttagga gacagagttt ctagtattgt
     1021 ttaattcttg aaaatcctag tggaaaagat ggagtgttct aaaataagtt ctgtttagcc
     1081 tccattcagt ttctattgag ttggatccaa tttctaacaa gtgggacatg ttcatgttcg
     1141 atctaaggaa gacatggtca tattcgaatg atattttcaa aaaaatcgta aaaaagtctt
     1201 gacaaagaaa aaacaaagta ttaaaataag ttcaacaaat cagaaaagta actatttttg
     1261 atcttcaggg agcctgtggt gattgtgaat aggtggttgg aagtagtgaa agtgggctga
     1321 ttttgaaaat gaatttgaaa caatgaaaat tcggtgcgca caccttacag tgcagcttgt
     1381 tgttaaacaa ggcagagatg taaagggata gtccctttat aattgaggtg gcaccgcgtt
     1441 accaacgccc tcacacggaa gtatattctg tgtgtgggct tttttctatc cgtcgtttgg
     1501 tttatctttt attagggcct taagtcgctt tgatgaactt gagttctatc tacagctcca
     1561 tgcctactac taaaagcaaa caaaaaggct ggactaatac gaaaaaagct agtaatactc
     1621 aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaaac actgttttga
     1681 ggttgtggat agaactgacg aagtcagtaa ccatacctac ggcaaggcga cgttgacgcg
     1741 gtttgaagag attttcgaag agtataaagg tgtaccgaga tgaacatctc ttcatcaatg
     1801 tctctggtcg tggaggcaag gacctagctg cgattgcaga ttactagaag ctaaaaaata
     1861 atagatggaa aaattacagt tctttctctc acagagagct tgtggttgct gaaaacaagc
     1921 agagaaagct gtaaagttgg gttcatctga aacgagagaa gaaaacatca ttctcaaggg
     1981 agtgcccttt atcgcacagc ctgttacagg agatatctga gacaggaatg agagatagga
     2041 gaaatcctat aattgaggtg gcaccgcgaa tttcgtcctc acgcaagtta ttttgcgtgg
     2101 ggatttttca tacagtcacc acggactaga agtagaactg aaagggaaat tacaatggaa
     2161 cgaatcattc atggagatgt cttatcacca atcttggctt atatgcgctt aaaggggcaa
     2221 cataaggtta ttttagagag tattccgaga gacaaggaaa cagctcgttt ttctatccta
     2281 gcctataatc cagtttttga gattaagttt gaaaatgggg ttctctatca aaatggtcaa
     2341 gtgattgatc gggatccctt ggatttcctt tatgaagtga ttcataagag tcagcaccac
     2401 tcagagctac cttttggtgg tggagccatt ggttttgtgg gttacgatat gatttcgctt
     2461 tatgaagaaa ttggtcaaat ccctgaggat acaattggga cgccagacat gcatttcttt
     2521 gtctatgaga gctatatggt ctttgaccac aagaaggaga agatacatgt catagaggat
     2581 gcactttata gtgagcgcag tcaagaggcc ttggaaaaat ccttgaacca agtgcttgag
     2641 gaattacgca ttcctgctcc aaatgaattt gaagatttgg atctatctcc gttagacttc
     2701 aaaccgcata tcgctccaca taagtttgag ggaatggtag aaacagctcg tgacttgatt
     2761 cgtaacggag atatgttcca atgtgtactc agccagcgtt tttcagcaga agttactgga
     2821 aatccatttg acttctacag aaatctccgc gtgactaatc cttctaatta cctttatttc
     2881 tatgattttg gggattatca aatcatcgga gctagtccag aaagtttagt ttctgtcaaa
     2941 aatggcatcg tgacaaccaa tccgattgca gggacgcgac caagaggggc tacggatgaa
     3001 gaagacaaga ccttggcgac tgacctcctc tctgatgaga aggaaacagc agaacatcga
     3061 atgttggtag acttggggcg taacgatatt ggccgcatct ctgaaacggc cagtgtccaa
     3121 gttactaagt atatgaaggt ggagctcttc cgctacgtca tgcatttgac cagcgtggtc
     3181 aaggggcgtt tgcttccaga actcacggcc atggatgcct tgaaagctac acttcctgct
     3241 ggaaccgttt ctggagcacc aaagattcgg gcgatgagac gcatctatga actggaaacg
     3301 gaaaaacggg gcgtatatgc aggagcaatc ggctacttgt ctgcgacggg tgatatggat
     3361 ttggccattg ccatccgaac catgattctc aaaaatcaaa gagcctatgt gcaggctggg
     3421 gcagggattg tctacgactc tatcgcccaa aacgaatacc aagaaaccat taacaaagca
     3481 aaatctatga ctagaattgg agaactaaga ccatgatttt attgattgac aactatgatt
     3541 cttttaccta taacttggcc caatacattg ggaattttgc agaagttcag gttctgagaa
     3601 atgatgattc caagctgtat gaagaagctg aaaaagcaga tggtctggtc ttttctcctg
     3661 gtcctggttg gccagttgat gctggaaaga tggaagacat gattcgtgat tttgcaggca
     3721 agaagccgat tcttgggatt tgtttgggcc accaagccat tgcagaagtc tttggtggta
     3781 agctaggttt ggctccaaaa gtcatgcatg ggaaacagag caatatcaac tttgaagcgc
     3841 catctgtttt gtatcaaggt attgaggaag gacgtgcggt catgcgttat cacagtattt
     3901 tgattgagga aatgccagaa gactttgaag tgacagctcg ttcgactgat gaccaagcca
     3961 tcatggggat tcaacataaa aacctaccga tttatggctt ccagtaccat ccagagagca
     4021 ttggaacgcc agacggcttg tcttctattc ggaattttat cgagaaggtt gtaaagtgag
     4081 gaaactagga tgaaagagat tattgaaaaa ctagcaaaat ttgaaaattt atcaggtgtg
     4141 gaaatgacgg atgtcattga gcgtatcgta actgggcgtg taactgaagc gcagattgct
     4201 tctctcctct tagctcttaa gatgaagggg gaaacacctg aagaacgcac agccattgcc
     4261 caagtcatga gaggacatgc ccagcatatt ccaactgaga ttcatgatgc catggacaac
     4321 tgtggtacag gtggggacaa gtctttcagt tttaatattt ccacaactgc agcctttgtc
     4381 ttggctggtg gcggtattca catggccaag catggtaacc gctcgatttc ttctaaatct
     4441 ggttccgcag atgtcctcga agccttggga atcaatcttg acctcaaacc agctgaacta
     4501 ggtaaggtct ttgataaaac tggaatcgtc tttctcttcg ctaaaaatat gcacccagct
     4561 atgaaataca tcatgccagc tcgtttggaa ttgggaattc caacgattat gaacttgact
     4621 ggtccactga ttcatccaat ggctttagaa acacagcttc ttggaattag tcgtccagaa
     4681 ctcctagaaa gtacagctca ggttttgaaa aatatgggtc gcaaacgtgc catcgtggtt
     4741 gctggaccag aagggttgga tgaagctggc ttgaacggaa caaccaagat tgcacttctt
     4801 gaaaatggcg aaatcagctt gtcaagcttt actccagagg atttgggaat ggaaggctat
     4861 gctatggaag atattcgtgg tgggaatgct caggaaaatg cagaaatttt gcttagcgtt
     4921 ctgaaaaacg aagcaagtcc attcttggaa acgacagtct tgaatgctgg tcttggtttc
     4981 tatgctaatg gtaagattga tagcatcaag gaaggagttg ccttggctcg tcaagtgatt
     5041 gctagaggca aggcccttga aaaactcaga ctgttacagg agtaccaaaa atgagtcagg
     5101 aatttttagc acgaatctta gagcagaagg cgcgtgaggt ggagcagatg aagctggagc
     5161 aaatccagcc tctgcgccag acctatcgct tggcagaatt tttgaagaat catcaggacc
     5221 gcttgcaggt aatcgctgag gtcaagaaag ctagccctag tttgggagat atcaatctcg
     5281 atgtggatat tgtgcaacag gcccagactt atgaagaaaa cggagcagtg atgatttcgg
     5341 tgttgacaga tgaggttttc tttaaagggc atttggatta tctacgggaa atttccagtc
     5401 aggtagagat tccgacgctc aacaaagact ttatcataga tgaaaagcaa atcatccgcg
     5461 ctcgcaatgc aggtgcgaca gttatcttgc tcattgtggc agccttgtcc gaagaacgcc
     5521 tcaaggaact gtatgactac gcgacagagc ttggtctgga agtcttagtg gagactcaca
     5581 atctagctga actagaggta gcccacagac ttggtgctga gattatcggg gtcaacaacc
     5641 gcaacttgac tacctttgag gtcgacttgc agaccagtgt agatttagcc ccttactttg
     5701 aggaaggtcg ctattacatt tctgaatctg ccattttcac agggcaggat gcggaacgac
     5761 tagccccata ctttaacgga attttggtag ggacagctct tatgcaggca gaaaatgtgg
     5821 cccagagaat caaggagttg cagattgaca aaggttaaaa tttgtggact atcgaccaaa
     5881 gaagcggtgg aaacagccgt ttcagcagga gccgactata tcggttttgt ctttgcacct
     5941 agtaaaagac aggtgacttt agaagaggca gctgagttgg caaagcttat tcctgcagat
     6001 gtgaaaaagg ttggagtatt tgtttcacca agtcgggtag aactgctgga agcgattgac
     6061 aaagttggct tggacttggt tcaagttcac ggtcaggtgg cagatgattt atttgagaat
     6121 ttgccttgtg ctagcattca ggctgtgcag gtagatggag agggtcatgt gcccaattct
     6181 caggcagact atctactctt tgatgcccct gtggctggga gtggccagcc ctttgattgg
     6241 ggtcaactgg atacgactgg attacctcag tctttcttta tcgcaggtgg gcttaatgaa
     6301 gacaatgtag taaaagcaat tcaacacttt actccctatg cagtagatgt atcaagcgga
     6361 gtggagacag atggacaaaa agatcatgaa aaaattagaa gatttataga gagggtaaag
     6421 aatggcatat caagaaccaa ataaagatgg attttacgga aaattcggcg gacgttttgt
     6481 cccagaaaca ttgatgacag cagttttgga gttggagaag gcctaccgtg aaagtcaggc
     6541 agacccaagt ttccaagagg aattaaacca acttttgcgc cagtatgtgg gacgtgaaac
     6601 tcccctttac tacgcaaaaa acttgaccca gcatatcggc ggagccaaga tttatctcaa
     6661 acgggaagac cttaaccata caggagccca caagattaac aatgccttag gacaagtttg
     6721 gcttgccaaa cgcatgggta aaaagaaaat tatcgcagaa actggtgctg gtcagcacgg
     6781 tgtggcaact gcaactgctg cggccctctt taacatggaa tgtaccatct acatgggtga
     6841 ggaagatgtc aaacgccaag ccctcaatgt cttccgtatg gagcttttgg gagctaaggt
     6901 cgaggccgtg acagatggtt cgcgcgtgct caaggatgcg gtcaatgcag ctcttcgttc
     6961 atgggtggct aatatagatg atacccacta tatccttggt tctgccttgg ggcctcatcc
     7021 atttccagaa attgttcgtg acttccaaag tgtcattggt cgagaggcta aacaacagta
     7081 ccgtgacttg acaggacaaa atctgccaga tgccctagta gcctgtgttg gtggtgggtc
     7141 gaatgccatc ggtctcttcc atccctttgt agaagatgag tcagtagcca tgtatggagc
     7201 tgaagcggct ggacttggtg tggatacgga gcaccacgca gctaccttga ccaagggtcg
     7261 tccaggtgtc cttcacggtt ccctcatgga tgtgctccaa gatgcccatg gtcaaattct
     7321 tgaagccttc tctatctcag caggtttgga ctatcctggt atcggtccag agcattctca
     7381 ctaccacgat attaaacgtg ccagctatgt ccctgtgaca gacgaagaag ccttggaagg
     7441 attccaactc ttgtctcgtg tggaagggat tatcccagcc ttggaatcta gccatgctat
     7501 cgcctttgcg gtgaaattgg ccaaagaact tggaccagaa aagtctatga ttgtctgcct
     7561 atcaggtcgt ggggacaagg atgtggttca agtcaaggac cgcttggaag cagatgcagc
     7621 aaagaaggga gaagctcatg cctaagacac taacagaaaa attaaatgct attaaagcag
     7681 ctggaaaagg aatttttgtt ccctatatca tggctggtga ccacgagaaa ggtttggacg
     7741 gtcttgctga aacaattcac tttttagaag atttgggtgt ctctgcaatt gaagtgggta
     7801 ttcccttttc agaccctgtt gcagatggac ctgttatcga agaagctggc ttgcgcagtt
     7861 tagcccacgg gacctctacc caggctttag ttgaaacctt gaaaaccatt gaaacagaga
     7921 ttccactggt catcatgacc tacttcaacc ccctctttca gtacggtgtg gagaactttg
     7981 tcaaagatct ggctgataca gctgtgaagg gcttgattat cccagacctg cctcatgaac
     8041 atgccaactt tgtagaacca tttttggcaa atacagatat cgccttgatt cctttagtaa
     8101 gcttgaccac aggaattgag cgccagaaag agttgattgc aggggcggag ggattcgtct
     8161 atgccgttgc catcaatggg gtgacaggga aatcaggcaa ttaccgtgca gatttggaca
     8221 agcacttggc gcaacttcat caagtggccg acatcccagt cttgacaggt tttggtgtat
     8281 ctagtcaagc cgatctggaa cgcttcaatg cggtgtcaga tggtgttatc gtcggttcaa
     8341 aaatagtaaa agctctccac caaggagagc cgattcagga ttttatcaga caagcagtag
     8401 cttaccaaaa ataatcaaac aagtagcaag taagaggaaa ggcacgaaag gaagtctttc
     8461 ctttttcttt tgcaggagaa aggtcagttt tatagtgaat tgaatctgga atattacact
     8521 acggttccta aaatattttc agaaagcgat ttgaatttcc caataaattt gttcagtttt
     8581 taattgattt tactatagaa gatataattt tctaaattac tctgacacag aactttaaga
     8641 aaaagataat tattgtagta atttctttaa gaaaatgata taattcatta aaaagtattt
     8701 ggaggaggaa gaattatgtt gaatcaggat ctctttgatt cgcttgaggc acaaaaaatt
     8761 gtagatactt tgatgaaagg gcaaaaagat tatgtagatg aacgtctaga aaaaagagag
     8821 acaatgatag tgtcgaatgg ttatgcatgg acgcgaccta atcatattga tactgcattt
     8881 gcatcagcag atttgtttga gtataaatta caattagcag gacagacttg gggatattta
     8941 gaatttgaaa caaatacaga aaaatatggg aaagtattgt taattataaa gggtaagaag
     9001 cgacttacga accaatttcc tttggtacaa aaaaataaga gtggctactt atttgaatac
     9061 gctcagatga atacacttta tcttaatcaa cattcttcct acaaaaatga tgaagatagt
     9121 cattcctttc caattcagat ggagttagtt tctgatgaaa tgattcaaga aattgaacaa
     9181 gctactaaaa attcgaatat cgaaaaattt atgattttaa cttatgaggc ggactcagaa
     9241 aacaatatta tatctgtaga tgttgttatg cctgatgcac gaactggtca gctacacttg
     9301 attcaagatt tgtctgagta tattcaatca agttcgtacc atttcgaaga agctaaatat
     9361 caagatattc ctaatttttc agaattatcg gaaacagaag attttgaaat tattccaaga
     9421 atagaaaaac aagaaggtca aaagtagtaa ggagtatata aatgtttaat ggtcgggtat
     9481 tgaaagaatt acggctgtta aatggtttaa gtagagcaga attagctcag agaattaatt
     9541 taacggaaca agccatttgg cagtttgagt ccaacgaaac gaaacctaaa ttatcaacca
     9601 aaatgcattt ggccaaccaa tttcatgttg atttaactta ttttgaacag gaagaagaga
     9661 gcattcgatt tgattcttct gtaattgcct ttagaaatgc agacctagca acacggaaaa
     9721 caatagatat tcaaactatg tatttacata aggtagatag tttgattgat tattttgaaa
     9781 gttttgtaat tatacctaat attataattc atgacctaag taatgtagtg agtgaatctt
     9841 atcataaggg agaatccatt gaggaattgg ctctttatgc cagggaaaaa ttaggtattt
     9901 caaaagataa tcatgatttg ctttataaat tagaacgttc aggtatctat atcgtggaac
     9961 gattaattaa tggccaagct gatgcttata gcgcatggtc aaaattggga agaccttata
    10021 ttgtgttggg aacgaataaa tcatctgtac gtcgaaattt tgacttagct catgagctag
    10081 gacatattct tttacataaa tataaggata tgaatgaaga tggcgatcgt ttggagcaag
    10141 aagcaaatta ttttgcatca tgttttttat tgccaaaaga agagttttta gtcaaatttg
    10201 aagagagggt tggcaagcgt gccagcaatc ctgatagtta tattttattg aagtcggatt
    10261 tgaatgtttc gatacaggct ttagagtatc gagcttttaa gttaggatta ttgactccaa
    10321 agcaacattc ttacttttat cgtcaaattg cgcaaaaagg ttacaaaatg attgaacctt
    10381 tggatgatca aatttttgtt aaaaaaccaa gcaaagtaaa gagtattctg gacgtcgttt
    10441 tgagtaatca tctagtcagt ctagcgacta taatgtctaa acaaagtatt tgtttacagt
    10501 ttataagcga aatattttca gtcgaaatga aattttttga tcagtatcaa gaagatagaa
    10561 gaacagatcg atttgataac atcatccctt tgtacaaaag aaataattta taatttaact
    10621 gtgaaataat ttcatgaagg acatatggca gaaattggat tttatcagac aagcagtagc
    10681 ttaccaaaaa taatcaaaca agtagcaagt aagaggaaag gcacgaaagg aagtctttcc
    10741 tttttctttt gcaggataaa ggccaggata cccgtcgcag aagcaaactg aatcaagatc
    10801 agtaactccg ttacgctaaa gacgagagca caagaagcta aaaagaggaa atctcctgcg
    10861 cccatgcgga tatcgataaa atgagccaaa attccaagag caaggaagga gaccatgacc
    10921 agattccagc cagaggaagc tattaggatt aggtggaaag tcatccagac cagtaaggga
    10981 tattcctgat ggtgaaagtc gtagataccc aaggtcaaac cagcggtgat taggacgact
    11041 tgccccaagg aaagcaattc ccaagagtaa agcagaaaga ggagtcctaa gactaattca
    11101 aagagggcat accagacagg atagcgaact ttgcagtagc gacagcgaaa gcgattgaag
    11161 acctgtgaga gaatcggaat caaatctaag ggacgcaagc gagtctgaca ggaatcgcag
    11221 tgactggctg aactgataat ggattgctct ggaaaacggt caatgaccaa accaagaaag
    11281 gaagcgagaa tgctcccgac gagaaaaaaa taaaaatcaa tcatacttat ctattcgtaa
    11341 aaaatgggag aaatagtata atggagaaac atagataaga tggtgaggaa aagatgacaa
    11401 ttcgttttga agaaaaggtg agtatagaaa acgctcaatt tgtatgccag tggtccaact
    11461 ccctaggcaa atcctttcaa gaacaatgga tgggaccaag gattcctttt ctactgaccc
    11521 ttcaagcctt ggaaggagtc ttttcaatct ttgatgaaca agagtttgtg ggacttatcc
    11581 agaaaatcag gctagaagac agcaatcttc atatcgggag attttttatc aacccccaga
    11641 aacaggagca agacttaggt agccaggctt taaggaaatt tgttagtttg gcctttgaaa
    11701 atgaagatat agatagtatt tctctaaatg tcttcgaggc aaatcaaaga gctcagaatc
    11761 tttaccaaaa agaaggattt gaaatcgttc aaatg
//
LOCUS       DAVLCS010000055        11071 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLCS010000055 DAVLCS010000000
VERSION     DAVLCS010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11071
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.055"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            15..377
                     /locus_tag="VXC78_001860"
     CDS             15..377
                     /locus_tag="VXC78_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583877.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGRILA
                     IIGGSLFLATLKKFKSEE"
     gene            912..1604
                     /locus_tag="VXC78_001861"
     CDS             912..1604
                     /locus_tag="VXC78_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV0583878.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1657..4044
                     /locus_tag="VXC78_001862"
     CDS             1657..4044
                     /locus_tag="VXC78_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0583879.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GSERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNSDYHLNVNLQMNY
                     WPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHTQATPFGWT
                     APGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFWNAFLHKDQ
                     QAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLLTEVKEKSD
                     LLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSYKGQEYIEA
                     ARASLNDRGDGGTGWSEANKINLWARLGDGNRAHKLLAEQLKTSTLQNLWCSHPPFQI
                     DGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSMSWEDKKLL
                     QLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDLVQFYF"
     gene            4294..4995
                     /locus_tag="VXC78_001863"
     CDS             4294..4995
                     /locus_tag="VXC78_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583880.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNSDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            4997..7705
                     /locus_tag="VXC78_001864"
     CDS             4997..7705
                     /locus_tag="VXC78_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0583881.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7801..8292)
                     /gene="tpx"
                     /locus_tag="VXC78_001865"
     CDS             complement(7801..8292)
                     /gene="tpx"
                     /locus_tag="VXC78_001865"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV0583882.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8415..9344)
                     /gene="psaA"
                     /locus_tag="VXC78_001866"
     CDS             complement(8415..9344)
                     /gene="psaA"
                     /locus_tag="VXC78_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV0583883.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9376..10224)
                     /locus_tag="VXC78_001867"
     CDS             complement(9376..10224)
                     /locus_tag="VXC78_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0583884.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10221..10943)
                     /locus_tag="VXC78_001868"
     CDS             complement(10221..10943)
                     /locus_tag="VXC78_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0583885.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3247 a         2059 c         2525 g         3240 t
ORIGIN      
        1 aaggagattt tattatgaaa tcaagtggta tcgtcggtct tgtgggagga attttacttc
       61 ttatttgtcc ttttgtcttg ttgggaacag cggtaaatac agctgctaca actcttaatg
      121 gaggagctac tgcaggggct ttttcaggtg ttgccttact cttgaatgcc ttgaagattg
      181 caaatcttgt tcttggtatc attgctattg tttactataa aggagataag catgtaggtg
      241 cagctccgtc tgtactaatg attgtttctg gtgaagttag tctcattcca ttcttaggat
      301 gggttgggag gattcttgct attatcggag gatctctatt ccttgcaaca ttgaagaaat
      361 tcaaatcaga agaataaaag gtattttagc atgaaaagaa caaaaaagtt tatcggtata
      421 ggagtagctc tattatctct ttctcttcta gttgcatgtg gaacataaag ttcaaagaat
      481 acttcaacaa gtaatgatga gaagacagta gcaacatcca atagttcaaa agaaacaatc
      541 actttcgata caccggttgt aacagacgat gcgattgaat caatacgcac ttatgcagat
      601 tatatagatc tttataaaaa tatttttgat gattatttta ctaaagctga ggaaggtttc
      661 aaaggcacaa ctatggaaaa taatgactcg tttactaaac taaaagagtc aactcaaaaa
      721 ttattcgatg cgcagaaaaa aaggttaaat aatgaagata gaatagaaac aaccaaaaac
      781 aatgtgattg ccaaacattg tcaaacagtc ctttcctttt tggttttgac tagctttttt
      841 gtgaaaaatt gtgtaaaata gaatagataa acgaggggaa acctcggaaa atttaaagga
      901 gaatccatct aatggtaaaa ttggtttttg ctcgccacgg tgagtctgaa tggaacaaag
      961 ctaacctttt cactggttgg gctgatgttg atttgtctga aaaaggtaca caacaagcga
     1021 ttgacgctgg taaattgatc aaagaagctg gtatcgaatt tgaccaagct tacacttcag
     1081 tattgaaacg tgctatcaaa acaactaact tggctcttga agcttctgac caattatggg
     1141 ttccagttga aaaatcatgg cgcttgaacg aacgtcacta cggtggtttg actggtaaaa
     1201 acaaagctga agctgctgaa caatttggtg atgagcaagt tcacatctgg cgtcgttcat
     1261 acgatgtatt gcctccaaat atggaccgtg atgatgagca ctcagctcac acagaccgtc
     1321 gttatgcttc acttgacgac tcagtaatcc cagatgctga aaacttgaaa gtgactttgg
     1381 aacgtgctct tccattctgg gaagataaaa tcgctccagc tcttaaagat ggtaaaaacg
     1441 tattcgtagg agctcacggt aactcaatcc gtgcccttgt aaaacacatc aaaggtttgt
     1501 cagatgatga gatcatggac gtggaaatcc ctaacttccc accattggta ttcgaattcg
     1561 atgaaaaatt gaacgttgtt tctgaatact accttggaaa ataaaaaatt gtaagcctag
     1621 gattgatttc taggcttttt atgttagtat ggaagtatga taaggaataa aaaacaagat
     1681 tatgtactgg cctacaagca accagcttca accacttaca tgggttggga agaagaagct
     1741 ttaccgatag gtaatggttc tttaggagca aaagtatttg gccttatagg gtctgaacgg
     1801 attcaattta atgaaaaaag tctctggtct ggaggtccac ttcctgatag ttcagattat
     1861 cagggtggaa atcttcagga tcagtatgtt tttttagctg agattcggca ggctttggag
     1921 aagagagatt acaatctggc taaggaactg gctgagcagc acctaattgg gccaaaaacg
     1981 agtcaatatg ggacctatct gtcttttggg gatattcaca ttgagttcag ccagcaaggt
     2041 acgactttgt ctcaggtgac ggactatcag agacagttga atattagtaa ggcacttgcg
     2101 acgacttctt atgtctataa gggaacgcga tttgaacgtg aagcttttgc gagttttcca
     2161 gatgatctct tggttcaatg ttttactaag gaagggttgg aaactctaga ttttactata
     2221 gaactatcct tgacctgtga tttggcttct gatggaaagt atgagcagga aaaatctgat
     2281 tacaaggagt gtaagttgga tattactgat tctcatatct tgatgaaggg aagagttaag
     2341 gataatgatc tgcggtttgc tagttatcta gcttgggaaa cggatggaga tattagagtt
     2401 tggtcagata gggttcagat atcaggagcc agttatgcca atctcttctt ggccgctaag
     2461 acggattttg cccaaaatcc tgctagcaat tatcgcaaga aactagattt agagcaacag
     2521 gtgatagact tggtggacac agctaaagaa aagggctata cccaattgaa atcaaggcat
     2581 atcgaggact accaagcctt attccagcgt gttcaattgg atttggaagc tgatgttgac
     2641 gcatccacta cagatgattt gttaaaaaat tataagccac aagaagggca ggctttggag
     2701 gagctgttct tccagtatgg acggtattta ttgattagtt cgtccagaga ctgcccagat
     2761 gctctaccag ctaacctaca gggagtctgg aattcggact atcacttaaa tgtcaatctg
     2821 cagatgaatt attggccagc ctatgttacc aatctcctag aggcggtctt tccggtcatc
     2881 aactatgtag atgatttgcg tgtctatggt cgtctagcgg ctgtaaagta tgcaggaatc
     2941 gtctctcaaa aaggtgagga aaatggttgg ttggttcata ctcaagcgac tccctttggt
     3001 tggacggcac ctggttggga ttactattgg ggttggtcac cagctgccaa tgcgtggatg
     3061 atgcaaaccg tttatgaagc ctattcattt tatagggacc aagactatct cagggagaaa
     3121 atttatccca tgttgaggga aacggttcgt ttttggaatg cctttttaca taaggatcag
     3181 caggcgcagc gttgggtgtc ttctccgtct tattctccag aacatgggcc gatttcgatt
     3241 ggcaatacct atgaccaatc tctgatttgg cagttatttc atgattttat tcaggctgct
     3301 caggaattgg gactggatga ggacttgttg actgaggtta aggagaagtc tgatttacta
     3361 aatcctttgc aaatcactca atctggtcga atcagggagt ggtatgagga ggaagagcag
     3421 tattttcaaa atgagaaagt ggaggcccag catcggcacg cttcccatct agtgggactc
     3481 tatcctggca atctctttag ctacaaggga caagagtata ttgaagcggc gcgtgctagc
     3541 ctcaatgatc gtggagatgg cggcacaggc tggtccgagg ctaataagat caatctctgg
     3601 gcgcgtttgg gagatggcaa tcgagcccat aaattattgg cagagcagtt aaagacatcc
     3661 accttgcaaa atctttggtg tagccatcct ccttttcaga tagatggtaa ttttggtgct
     3721 actagtggca tggcagaaat gttactccag tctcatgcag cttatctggt acctctagct
     3781 gccctacctg atgcttggtc aacaggttct gtttcaggct taatggcacg tggacatttt
     3841 gaagtgagca tgagctggga agataaaaaa ctcttacagt tgaccatttt atcaaggagt
     3901 ggaggagatt tgcgagtttc ttatccagat attgagaaga gtgtgattaa aatgaatcaa
     3961 gaaaaaataa aagcgaaatg catggggaaa gattgtattt cggtggcaac agcagaaggt
     4021 gatcttgttc aattttattt ttaagaagat gttataaggc agtaatttga aactgccttt
     4081 taataaggat ttaagaatat aagcagtttt caactagttg aaaaaacgtt ataatgataa
     4141 taggaagtaa tactcaatga aaatcaaaga gcacaaacta ggaagctagc cgcaggttgc
     4201 tcaaaacagt gttttgaggt tgcagatgga agctgacgtg gtttgaagag agattttcga
     4261 ggagtataat ttgtttgata gagggtgggt ctgatggctt atattgagat gaaacactgt
     4321 tacaagcgtt atcaggttgg ggacacggag attgtggcca atcgtgatgt gaattttgag
     4381 attgaaaagg gggagctggt tattatcctt ggtgcttcag gtgcaggcaa gtcaacagtt
     4441 cttaaccttc ttgggggaat ggataccaat gatgaagggg aaatctggat tgatggtgtt
     4501 aatattgcgg attatagttc ccaccagcgc accaattacc gtagaaatga tgtggggttt
     4561 gtttttcagt tttataatct agtttctaat ctgacagcta aggaaaatgt ggaactggct
     4621 tctgaaattg tgacagatgc cttgaattct gatcaggtct tgacagatgt aggtctggct
     4681 catcgtctca ataactttcc agcccagctt tctggagggg agcaacagcg agtctccatt
     4741 gcacgcgcgg tagccaaaaa tcctaaaatt cttctttgtg atgaacctac tggagccttg
     4801 gattatcaga cgggcaagca ggttttgaaa attctccaag acatgtctcg tcaaaaggga
     4861 gcgacggtga tcatcgtgac tcataatgga gctttggcgc ccattgctga tcgcgtgatt
     4921 catatgcacg atgccagtgt caaggatgtg gtgctcaacc agcatcctca ggatattgac
     4981 agtttggagt actagcatga tcaagcgaaa aacttattgg aaggacttaa ttcagtcctt
     5041 cacaggctcc aaggggcgtt ttttatccat cttgatcctg atgatgttgg gatctctagc
     5101 cttagtaggc ctcaaagtaa ccagtcccaa catggaggcg acagctaatg cttatttaac
     5161 aactgctcaa accttggatt tggcagtcat gtctaactat ggcttggatc aagcagacca
     5221 agaagaacta aaacagacgg agggcgcaga ggtcgagttt ggctatttga cagatgtgac
     5281 tatggataat gggcaggatg ccattcgact gtactccaaa ccagagcgaa tttcaacctt
     5341 tcagctaaga aagggacgac ttcctcagtc agacaaggaa atcgctttgg ccactcattt
     5401 gcaaggccaa tacagcgtgg gacaggagat tagttttaaa gaaaaagaag agggtcattc
     5461 ctctttaaaa gaccatactt ataccattac tggttttgtg gattcggctg aaatcctctc
     5521 ccagcgagat atgggctacg caggaagtgg aagtgggact ctgacagcct atggggtgat
     5581 tttacctagt cagtttgatc agaaagtcta caatatagct cgtttgaaat atcaagattt
     5641 agcaggttta aatgcctttt catcagctta tgaagaaaaa tccaagcaac atcaggaaga
     5701 gcttgaacaa attttatcag ataatggcaa ggtacgtctg caacttttga aaaaagaagg
     5761 acaagagtct ctagacaagg ggcaagagac ccttgacaag gctcagacta atttgcagga
     5821 aggcaagcgt cgtttagcag ctgctcaagc tcgtatacag gctcaagaaa gtcaactagc
     5881 cttgtttcct caagttcaga gagagcaggc tagtgctcaa cttacccaag ccaagcagga
     5941 attgggcaag gaagaggcca aactaaagca agctgaacaa aatctagccc aagaaaagga
     6001 aaaattagaa aaacatcagc aagtcttgga cgatttggcg gagccaaggt atcaggtcta
     6061 taatcgtcag accatgccag gtggtcaggg ctatcttatg tatagcaatg cttcatccag
     6121 tattcgagca gtgggcaata tctttcctgt ggtactttat gccgtagcag ccatggtgac
     6181 ctttacgacc atgactcgct ttgtagacga agagcgaact catgcaggga tttttaaggc
     6241 cttgggttac cgtagtaagg atattatcac caagtttctc ctttatggac tagtagctgg
     6301 gactgtcgga acggctctag gtagtatact tggtcattat ttgctagcca gtgtaatttc
     6361 aagtgtcatt acaaaaggca tggtggtggg agaaacccag attcagttct attggaccta
     6421 tagcttacta gctcttgtct tgagcttgtt ggcgagtgtg ttaccagcct atctggtggc
     6481 ttggagggaa cttcatgccg aagcagccca gcttctactt cctaaacctc ctgtcaaagg
     6541 agctaaaatc ttattggagc gtatcggttt tatctggcgt cgtctcagtt ttactcataa
     6601 ggtaacagcc cgcaacatct ttcgttataa gcagagaatg ttgatgacaa tctttggtgt
     6661 ggcaggttct gtagctctgc tctttgcagg tttgggaatc caatcttctg tagcaggagt
     6721 tccgtctaaa cagtttcaac aaatccaaca gtatcagatg cttgtctctg aaaatcctag
     6781 tgcgaccaat caggacaagg tagagctagc agaagtgttg aaagggcagg agatactagc
     6841 ctaccagaaa atctattcta aaacgctaga caaggatttc aaaggcaagg ctggtcttca
     6901 aaacattact cttatgatga tagagaagga agatttgact ccctttatcc atcttcaaca
     6961 tcatcagcag gagctgacat taaaagatgg catcgttatt acagctaaac tcgcccagct
     7021 ggcaggtgtc aaggttgggc agactttaga aattgaaggt aaggaactaa aggtcgctgc
     7081 tattactgag aactacgttg gtcactttat ttatatgagt caggctagct atgagcaact
     7141 ttacggacag ctaccccaag ccaacactta tctggtctca ttaagggata ccagtgcaac
     7201 tagtatcgaa agtcaggcgg gcttgcttat gaatcaatct gcggtgtcca gcgttgtcca
     7261 aaatgcttca gccattcgac tcttcgactc tatcgctagc tcactcaatc agaccatgac
     7321 catcttggtc atcgtatcgg ttctattagc tattgtcatc ctttacaatc tgaccaatat
     7381 caacgtagct gagagaatcc gtgaactctc cactatcaag gttctcggtt ttcataataa
     7441 tgaagtcacc ctctacattt accgtgagac gattgtgctg tcccttgtgg gaatcgtact
     7501 tggtctggta gctggtttct atttacacca atttttgatt caaatgattt cgcctgcgac
     7561 tattctcttt tatccgcagg taggctggga agtctatgta atcccagtgg cagcagtaag
     7621 catcattttg accttgcttg gtttcttcgt caattattat ctgagaaagg ttgacatgtt
     7681 agaagccctg aaatctgtag agtaaggtag ttatttttag ctgattgaac ttctatttac
     7741 taatattcaa aaatcctccg tttcaaagag cagggaactc tttgtgacag aggatttttt
     7801 ctatagggct ttagcagctg caattgcggc ttcgaagttt ggctcagaat tgatattatc
     7861 cacgtattca acgtagcgaa tcgtattgtc agtatcgagg acaaagactg cgcgtgctaa
     7921 taggtgccat tcgttgatca agagggcata atcgtgcccg aaagaatggt caaagtagtc
     7981 tgaaagcata atggcattgt caaggccttc agcaccgcac caacgttttt gagcaaaagg
     8041 taggtccatt gaaacagtca atacgaccgt gttgtccagt ccagccaatt cttcattaaa
     8101 acgacgtgtt tgagttgagc agatgcctgt atcgatagaa ggaacgacac tcaagacttt
     8161 tttcttgcca tcaaaatcag ccagagattt tttagaaaga tctgttgtag taagagaaaa
     8221 atcaagcgcc ttgtcgccga cttgtagttg tttacctgta aagctcacag gatttccgag
     8281 aaaagttacc ataggatact ccaatctttt ttcttccatt gtatctgaaa cagtcagaat
     8341 tttccaatga tttgaccgga aatgtgggca tagaaaaaac gccagctcat atgagaatga
     8401 cgtttttcag aggcttattt tgccaatcct tcagcaatct tgtcaaggtt gtatttcatc
     8461 atgctgtagt agctgtcgcc ttctttacct tgttctgcga tagagtcagt aaagatttgt
     8521 gcgtagattg ggatgtttgt gtcttgagaa acggttttca ttggacggtc atccacactt
     8581 gattctacaa agagtgatgg aacttttgtt tggcgaagtt tttcaaccaa ggtcttgatt
     8641 tgttcaggag ttccttcttc ttcagtattg atttcccaga tgtaggcact tggaacacca
     8701 taggctttag agaagtattt gaatgctcct tcgctggtta caatgagttt cttttcagca
     8761 gggatcttat taaatttatc cttactttct ttatcaagtt tgtctaactt atcagtatat
     8821 tctttgagat ttttttcata gaattcttta ttgttagggt ctttggcgct caattgtttg
     8881 gcgatatttt tagcaaaaat aataccgttt tcaaggttaa gccaagcgtg tgggtcttct
     8941 tttccttttt cattttgacc ttcaaggtag ataacatcaa cgccgtcgct gactgcgaag
     9001 tagtctttgt tttcagtttt cttggcattt tctaccaatt ttgtaaacca agcattgcca
     9061 cctgtttcaa ggttgatacc gttatagaaa atcaaatcag cctcagaagt tttcttaacg
     9121 tcttcaggaa gtggttcgta ttcgtgtggg tcttgcccaa tcggaacgat actatgaagg
     9181 tcaattttgt caccagcaat atttttagta atatcagcga tgattgagtt tgtagcaaca
     9241 acttttagtt tttgaccaga agttgtatct ttttttccgc tagcacatgc tacaagaatg
     9301 attgcagaaa gaaagagaac gagtaatgta cctaattttt tcattagatc ctccaattta
     9361 ttagggcttt gccccttatt ttaacaaatg tttatttttc agtttcaaat atcgttgttt
     9421 gggagcgata aagaagctaa tgagaaagaa actagcagct gtaagcacga tactagaacc
     9481 tgccgcaaca ttaaaactat agccaataaa gagtcccaaa actgaagcag tagctccgaa
     9541 ggttgaggaa aggaaaatca tgcttttcag actattagca tacagataag cagttgcagc
     9601 tggggtaatc agcatggcta caatcaggat agttccgaca ctttgcatgg ctgtcacaga
     9661 cacgagagtc aggagtacca tgagaaggta gtgatagaaa ttgacaggca ttcccatggc
     9721 tttagccaag agttcatcaa aggaagttat caagagttgc ttgaagaaaa tccagattaa
     9781 caagaggatg gctgccccca cacccatagt aataaacata tccgtatctt ggacggccag
     9841 gatattacca aaaaggatat ggaaaaggtc agttgaactt ttagcgacac caatcaagat
     9901 gataccgagg gctaagaaag aagaaaaggt aatgccgatg gcggtatcgc ttttgataat
     9961 cgagtttcct ttgatgtagg taatgatgat ggcagctagc aatccaaaga caatggctcc
    10021 gataaagaag tcaaggccca agatgaagga gagggctaca cctggtaaga cagcatgtga
    10081 aatggcatct cccatgagtg acatcccacg tagaataatg aaacatccca cggctccagc
    10141 tacaatcccg acgacaatag ctgttatcaa ggcattttgt aggaaatgga atttttgcaa
    10201 tccatcgata aattctgcaa tcataggtca cctccattga aaaagagttg attaccgtaa
    10261 gcttctttta gattggtttc ggtaaaagtt tcttttgttg gaccaaaggc aatcacttct
    10321 cgattgacaa gtaagacttg atcgaagtag tggggaatct tgctgaggtc gtggtgaacg
    10381 atgagaaccg tcttcccagc ttttttcaaa tctctcagcg tattcatgat gatttcctca
    10441 ctgacagagt caatcccagc aaagggttca tccaagagga tatagtcggc ttcctgcacc
    10501 aaacatctgg caatcaagac ccgctggaat tgacctccag acagttgact aatttgacgt
    10561 tcagcgtagt cagctaggcc gacgatttca agggcctctt gcactttctt ccaatgttta
    10621 gcctttaaac ttcgaaagag aggaatagag ggaaatagtc ctaacgagac gcattccttg
    10681 accttgatgg gaaagttgta gtcgatattg attttttgtt cgacataggc aattcggtgt
    10741 aaggattttt taacttcctt gtcatcgaga aatgcctgac cttgatgtgg gataattccc
    10801 agcatacctt ttaatagtgt tgatttccca gcgccgtttg gaccaatgat gccggtaatt
    10861 gttggtccat ggagcactag tgaaatatcc ttaagtgcca acgtttcttt gtaggagaca
    10921 ctgaggtttt cgatacgtat cataaacttg tattcctcct gtctcttaat atacattaaa
    10981 aaaaaaatta agtcaagtta atttttgaaa aaattaaaat aataactgaa aaatagattc
    11041 taaagataac tttcaggata aatttctaaa t
//
LOCUS       DAVLCS010000056        10899 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLCS010000056 DAVLCS010000000
VERSION     DAVLCS010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10899
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.056"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(162..965)
                     /locus_tag="VXC78_001869"
     CDS             complement(162..965)
                     /locus_tag="VXC78_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV0583886.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(1049..1261)
                     /locus_tag="VXC78_001870"
     CDS             complement(1049..1261)
                     /locus_tag="VXC78_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583887.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            complement(1740..1949)
                     /locus_tag="VXC78_001871"
     CDS             complement(1740..1949)
                     /locus_tag="VXC78_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583888.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            2119..2391
                     /gene="rpsP"
                     /locus_tag="VXC78_001872"
     CDS             2119..2391
                     /gene="rpsP"
                     /locus_tag="VXC78_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV0583889.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            2411..2650
                     /locus_tag="VXC78_001873"
     CDS             2411..2650
                     /locus_tag="VXC78_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV0583890.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            2918..3122
                     /locus_tag="VXC78_001874"
                     /pseudo
     CDS             2918..3122
                     /locus_tag="VXC78_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            3226..4014
                     /locus_tag="VXC78_001875"
     CDS             3226..4014
                     /locus_tag="VXC78_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0583891.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            4045..4563
                     /gene="rimM"
                     /locus_tag="VXC78_001876"
     CDS             4045..4563
                     /gene="rimM"
                     /locus_tag="VXC78_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV0583892.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            4553..5272
                     /gene="trmD"
                     /locus_tag="VXC78_001877"
     CDS             4553..5272
                     /gene="trmD"
                     /locus_tag="VXC78_001877"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV0583893.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGSQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKILVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            5284..5622
                     /locus_tag="VXC78_001878"
     CDS             5284..5622
                     /locus_tag="VXC78_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583894.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(5653..5973)
                     /locus_tag="VXC78_001879"
     CDS             complement(5653..5973)
                     /locus_tag="VXC78_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583895.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            6071..6286
                     /locus_tag="VXC78_001880"
     CDS             6071..6286
                     /locus_tag="VXC78_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV0583896.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(6355..6435)
                     /locus_tag="VXC78_001881"
                     /pseudo
     CDS             complement(6355..6435)
                     /locus_tag="VXC78_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(6491..7027)
                     /locus_tag="VXC78_001882"
     CDS             complement(6491..7027)
                     /locus_tag="VXC78_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV0583897.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7453..7791
                     /locus_tag="VXC78_001883"
     CDS             7453..7791
                     /locus_tag="VXC78_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583898.1"
                     /translation="MKKRINKKASVFLVASVFSFSFATTASVVNAVTAHPAPSPIIDV
                     WEYGVNDNYGYSNYFVSSPSNIGSKSSVTNFWGTVKAQDKKDYGWAYSSATKSWNDVR
                     LNAYWDYYRF"
     gene            7857..9839
                     /locus_tag="VXC78_001884"
     CDS             7857..9839
                     /locus_tag="VXC78_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0583899.1"
                     /translation="MKLKLCIIGFFFCLIATIGLVTISDTEIPIPLPIDGAFSIQGKS
                     NLSNNEIYEMVRDLSKTEKVTIYKPIVQSSGQLKYVNFDDVNNEQLKSAPIVGMYYTL
                     GKMDVDSLKPLTMTGLQTVYMAYPWYIGGILQFTGTLRILLMGSIYLTLLVVLFVVRT
                     RQIKEGVIRRSLGLPIYDLRREYGISLIFELIMMALLMISYSSFLGNGFFTYSSKLFF
                     SLLLTNFILFQIIDLITFVLFWLTIQIEKPIEIIKNKAKNKLIFVVWLAIISIIILVS
                     GVFLQETKSSQSSINIQIQNLVPWDTVKDWRRIEFLGIESNSTKNREVNDSDGQYLQI
                     VAALKNLDFLYIERSSAYVPDFMKTSHVIENFSKQLENDGITNPEINKELIYINQTGA
                     NLQNKVNGTNYHLLDNKIATIYIPEKWKENQKSIENTVVAEQFIGTNYTREQLAVQII
                     PDGEKIFYFNEDADNNLKMKDILPLANVADSKDNIVVVLDTDKMMENNKFSLASNILY
                     KSLFSPEAVKKINEMTVLLNFSMNPVDVYQIVKLKIQSLEHQILLSQILQKIIYSIVF
                     ILIYQYVQLFITLKQNEYVKKIILGLSKTYIAISSLKYFMMTITMVILFTFLMTGQIE
                     LLYIGAASLLVLMLSIIMSFRKLSESYTKILKGDES"
     gene            9836..10459
                     /locus_tag="VXC78_001885"
     CDS             9836..10459
                     /locus_tag="VXC78_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0583900.1"
                     /translation="MTIDLLNVSKSFGSKKIFTDLNLIFESGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGNVLVDKQDIWKIKERTFFKNTVGYVFQNYSLIDNKTVYDNLSLIT
                     KDKKTITDVLEKVGLSSDYLHQKIYELSGGQAQRVAIARMLMKPRKIILADEPTGALD
                     GEIGKEIIRLLLNETAEDKYVIIATHDPAVYNEVDVIIDMKDIGYKV"
     gene            10456..>10899
                     /locus_tag="VXC78_001886"
     CDS             10456..>10899
                     /locus_tag="VXC78_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583901.1"
                     /translation="MKKKIYIALIFVTGVLAIFFFGKQMITKENINKPTVELTIYTLS
                     SSDTEKWNKVRQVETEEAIYFITVKEVSSSEEVFSNIIANGAATGFGVREEEVKKFNN
                     GLGDTIEDSKHNKLIEIEFFTFSDDGAGFVVANFDYGKEELNSQKK"
BASE COUNT         3670 a         1724 c         2160 g         3345 t
ORIGIN      
        1 tctttctaat gagttgtttt gtcgcttttc attataggtc atatgggact ttttttctac
       61 aataaaatag gctccataat atctatagtg gatttaccca ctatagatat tatagagcca
      121 gaaatacagt accgaatgtg gatactgtat ttttttggtt tttaagattt aaaatcgtag
      181 tctttcacca cttcgatgct gtcgattgtg atagcagtag ttggcttgtc tttttcatct
      241 ttttcggctt tagcaatctt atccacaaca tccataccgt caatcacttg accaaagact
      301 gggtgtttgc catctagact agggtttcca ccttctttgt aggcttcgat aattttctgt
      361 ggatacttgc ttgtagggag tttagaagag gtatctgtag agttttggtt gatgaagaac
      421 tggctgccat tggtgtttgg ttgaccagta ttagccatag caagagcacc acggatgtta
      481 tacaaataag gagtaatctc gttcttgaaa ccagttcctt tgtctttagt cttatccttg
      541 tcatgccata tggactgacc acctgtaccg tccccttttg gatctccagt ttggaccata
      601 aagccatcga tgacacggtg gaaggtaata ccgttatagt agccttcttt ggcgtgagtg
      661 aggaaatttt caaccgctag aggagcgagt ttagggaaga gtttaatgcg aatatcacct
      721 tggcttgtgt ggagaatcac ttcggcttca tcttcagcaa cttccttaga tagttgtggg
      781 aaattggcgt tttcgtttgt taaagcatcg tttaactcct tggcagattg ggcagctact
      841 ttggaacttt cttcagcagc aagactggaa tcaacataat catcaccacg cagactgcgt
      901 tggacgctgc tacacccagc tagggctaca gtagacagta aaagaagggt tgctagtttt
      961 ttcattctga tcctctcaaa aattcattta taaccattgt accctaaaag gaagtggatt
     1021 tcaaatatta gtagtttaca gaactggctt agataatagt tgggatttca tcatcatctt
     1081 gaaaatcttc aacttcttcc ccagtaaatg gtttctgaaa agaacttagt ataaaacggg
     1141 caattggttc aacaattagg aaatttagag gaagagctgc aataaagttt acgaaccagg
     1201 cgcttagata ggtattgggt gtgatagcaa tgccattgta aaaaagtcca tagaaggaca
     1261 tgaaagtgac cagctaattc ttcttctgaa aaatgctcat gaagggcttg atccaggtcg
     1321 caagatttca ttttagaaag tccagtaact cccttcttct tcaggatatt ctttttcatg
     1381 gtagtattta gatggtcaag tgagtcaaaa gaagtttcga caagagcata ccctttttct
     1441 accagagttt ttagatgttt aggggcatca ataccataag tgtactcaaa gtattttgga
     1501 aaccagatct taagaaagct cgtaaagcta gccagttctc taaacgctaa gaactagcta
     1561 caacacagca tttacaacac ttcatggttc acaccatggg gtgtttttta atgattttaa
     1621 gcaaaattca cacttaattg aaagttattt aaattagatg aaaatttatt ttttgaaaaa
     1681 gtgggaaaac attgattcta agcgaatttt gaatcatatt cgaatgggag tttttaaaat
     1741 catgtttcag tggtaaaagt accaaactgg attctccata gtaaaatgat atctcctgct
     1801 agtgaatcat ctactaataa gtccatattt cgcttgggaa cgggcttggg acttagaagc
     1861 caagtatcca actctcgttc aggcgatatg aagggtttga cttggtgttc tttataaaat
     1921 ttttctaaaa tagtattcac ggatagcatc tttcaaacat ttatttccta ttctaacaaa
     1981 tttctaaata ctttaagaaa tttatagtct gtcaagtttt tttcttgaca catgccagaa
     2041 atctgctata atagaacatg tgctagatag ctcagctatt tcaccgaaat aaaaaattaa
     2101 agaaatgaga ctttaaaaat ggcagttaaa atccgtttga ctcgtatggg ttctaagaaa
     2161 aaacctttct accgtatcaa cgtagcagat tcacgttcac cacgtgacgg acgtttcatc
     2221 gaaacagttg gaacttacaa cccacttgtt gctgaaaacc aagtaacttt gaaagaagac
     2281 cgcgttcttg catggttggc taatggagct caaccttcag acacagtacg taacatcctt
     2341 tcaaaagaag gcgtattgaa aaaattccac gattctaaat tttcaaaata agtttaaagt
     2401 aggttgacag atggatacga ttgaaaatct cattattgcg attgtgaaac ccttaatttc
     2461 acaaccagat gccttaacta tcaagattga ggatacacca gaatttttgg aatatcattt
     2521 gaatcttgat caaagcgatg tgggtcgtgt aatcggtcgt aagggtcgca ctatttctgc
     2581 gataagaacg attgtctact ctgtcccaac tgaatacaaa aaagtaagaa tcgttattga
     2641 cgaaaaataa gaagggcggg acggatgtct cgcttttttg tgtggaatag aagatatagt
     2701 aaaatgaaat aataacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt
     2761 ttagaagtaa aggtgtacta ttctagtttc aatatactat aaaagattga acgtttaggc
     2821 aattccaaga ctacttactc gaacattaac agcagtctcg gactgatgaa ggtctcttta
     2881 tgaagttagt ggagaagtcg gagaagtagc cgaggttttg aataggcgct ctggtcgaaa
     2941 agaagggata ggattcgaac gaggaacttg ccagagaact ggctgatatc atttactaca
     3001 ccgtcgcaat cgtagctatt aatcatattg accttaccaa gactgtcttt gagaaagaca
     3061 aaaccgcagc cgttaattac caacataaac atgatttgga aggatttttg aagggaaagt
     3121 agagatgttg tccccttcct ccaacttgag aaaatccttg gaacgtgata aaataaaaga
     3181 taaggatttt taataattca ttatatagaa tgagtggatt tctttatgaa gaggtttgaa
     3241 gtatctacag aaattggtag cctctctgtt acttatcaaa agcaaaagaa agtgctagtt
     3301 tgtctaaacg gagcaggttt gctaccaagt tatgaaaatt tttcacttat acttgaaaaa
     3361 cctcctccta caattggtta tttgacaatt gattttccga acacaggtag gagtccgatt
     3421 catgaccaag ctggaaaaaa tctagataat cttgcagatg tggtttatga agtacttgaa
     3481 gaattaggga tttctgaata tatactttgt gcacatagtt ggagtggaat tttagcttgc
     3541 aaattactcg agaaaccaat taagtgtcag actttagtag caattgaacc gacaactaaa
     3601 aaagtcatgt ttgctgattt ttcagaaaat ccttatccag aaatggaaga gcagatgagg
     3661 ctgattgacg agtgtggtcc tgaactttat tttaagaact taactcaagc aacatttagt
     3721 cctgaaacga ataaaaaaat ctgggaatta atgcaagaaa aaggcttaga gttggaaaat
     3781 caagatccag aatttcagat atctggagag attactgagg aagattttga gaatttgtcg
     3841 atagaatctc atgtccctgt atttattttt tgtcagactt atagagaaaa agagtacaga
     3901 gaatcagaat attggacttc taatactaaa ctcattttag gagggaatca ccattattta
     3961 caatggtcag aatcggaaaa aattgcggct attattcgag aattgtcaga ataagatgga
     4021 aaaaaggaga ttacaggaga caagatgaac tactttaatg ttgggaaaat cgttaatacg
     4081 cagggattac agggtgagat gcgagtcttg tctgtgacgg attttgcaga agaacggttt
     4141 aaaaaaggag ctgagctggc tttgtttgat gaaaaagatc agtttgtcca aacagtgacc
     4201 atcgctagcc accgtaaaca gaagaacttt gacattatta aattcaaaga tatgtaccat
     4261 atcaatacta tcgaaaagta caagggatat agtctcaagg tcgctgagga agatttgaat
     4321 gacctagacg atggtgaatt ttactatcac gagattatcg gtttggaagt ctatgagggt
     4381 gatagcttgg ttggaaccat caaggaaatc ctgcaaccag gtgctaatga tgtctgggtg
     4441 gtcaaacgaa aaggcaaacg tgatttgctt ttaccttata tcccaccagt ggttctcaat
     4501 gttgatattc caaataaacg ggtcgatgtg gaaatcttag aagggttaga cgatgaagat
     4561 tgatatttta accctctttc cagagatgtt ttctccactg gagcactcaa tcgttggaaa
     4621 ggctcgagaa aaagggctct tggatatcca gtatcataat tttcgagaaa atgctgaaaa
     4681 ggcccgtcat gtagatgatg agccctacgg aggcagtcaa ggcatgttgc tcagagcaca
     4741 acctattttc gattcctttg atgctattga aaagaaaaat ccgcgcgtta ttctcctcga
     4801 tcctgctgga aagcagtttg atcaggctta tgctgaagat ttggctcaag aggaagagct
     4861 aatctttatc tgtgggcact atgagggtta tgatgagcgc attaagatct tggtaacaga
     4921 tgagatttcc ctaggcgact atgtcctcac tggtggagaa ttggcagcta tgaccatgat
     4981 tgatgctaca gttcgcctga ttccagaagt gattggcaag gagtctagcc accaagatga
     5041 tagtttttct tcaggtcttt tagaatatcc tcagtacaca cgtccctatg attatcgagg
     5101 catggtcgtg ccagatgtat tgatgagtgg ccaccatgaa aagattcgtc agtggcgatt
     5161 gtacgagagt ttaaagaaaa cctacgagcg cagaccagat ttacttgaac attatcaact
     5221 gacagtagaa gaagaaaaaa tgctggcaga aatcaaagaa aacaaagaat aaaggagaaa
     5281 cctatgcaag taatcaaacg taatggcgaa attgctgaat ttaatccaga taagatttac
     5341 caagccatct tgaaggcagc ccaaactgtt tatgttttga cagatgattt gcgtcaaaat
     5401 cttgctcaag tcactaagaa ggtagttttg gatttacaag aagccaaggt ggaacgtgcg
     5461 actatcagta tgattcaatc tatggttgaa catcgtttat tgggcgcagg ttacattacc
     5521 attgcagaac actacatttc ctatcgttta caacgtgact tggaaagaag tggttatgga
     5581 gatcatattg cagttcattt acattttgaa caaattcgct aagaaaaaag agtgggatga
     5641 agcaactaca tctcactctt tcttaaatct atttttttgg gctgtttgga cagttgaggg
     5701 gacaaatcgc aggcgttgaa tatcgcttat acggataatc cggctcacat ttttggcaaa
     5761 atttttcacg ataatttgct ggccttgctg atcatatttg atgatatcac ctgtaaaact
     5821 tgtctcagac aagataaggt gaacagcggt ttgtttctgg atagcctctt caatagtggc
     5881 tgtaagggag ttggtttcag tctggtcagg ttggtcatgt ccatttaaaa aatcatgtat
     5941 tttatctaga acttgctgga atttatgtct catattggcc tcccttcttt tatatcaata
     6001 ttatataaaa ttttcctaaa atctacaaga ttttacgaat aaactaatga aactaaaaaa
     6061 ggagaagaaa atggcagaat ttacatttga aatcgaagag cacttgttga ctctttctga
     6121 aaacgaaaaa ggttggacca aggaaattaa ccgtgtgagc tttaatggtg cccctgcaaa
     6181 gtttgatatt cgtgcttgga gtccagacca tactaaaatg ggcaaaggga ttactctctc
     6241 aaatgaagaa tttcaaacga tggtggatgc ctttaaaggc aactaatact cttcgaaaat
     6301 ctcttcaaac cgcatcagct ttgccttgcc gtatgtatgg ttactgactt cgtcagtttc
     6361 atccacaacc tcaaaacagt gttttgagca gcctgcggct agcttcctag tttgctcttt
     6421 gattttcatt gagtataagt tttcaaaata aaaaaaagga tattgagtca tgataactcg
     6481 gtatcctttt ttagttagta aagtaagcct gatttttaag gcgttgaagt aggggacggc
     6541 taataaaact aatagccaga agtttgccaa ggtctggaat gataaaggga agaaccccca
     6601 caacaagagc tttttcaaat gccattccag ctaggaaatg caagctgaga atcccgccga
     6661 caaagacaag ggcatcaccc aagaggtttg caagaaaaat cttaacaaca ccactcttgc
     6721 tgttggttag agaggaagta agtccagagt aaacgagata aaaccaaaga tagcctgcag
     6781 tagggccaac taaagcctga aaaccagctc cacctcctgc aaagacagga agaccgatag
     6841 cacctagaag aagatagagt ccagcagaaa gtacagcctc tctcggtcta aagacagtag
     6901 caatcaagcc gattgcaaag ttttgcagag tgaagggaac aggtccaatt ggaagactga
     6961 tttgtgccaa aacagcaatg agagcagccc caatagcagg gatagcataa acgtgagctt
     7021 ttttcaaaat agttaacctc ttttctaatg tatagtaact attatactca tataggagtc
     7081 gatgtcaacc attttttaaa aacaaggtaa caaaaactgt aacagccgat tttcgtgact
     7141 agtcaagttg gataattttt ttgttgattc gaaaattgtc tgtatagata atcctatttt
     7201 attaataaaa aatatactag taaatacttg acaaattaaa aaataagtgt tacattaaaa
     7261 atgtaaacgg atacatttag atgtgttcaa ttttaaaagg aggggtagtt atgagatatt
     7321 ttaacgactc tagataccat aacggtgatt aaaaacctaa atataatcaa ttcatattaa
     7381 agtaatatgg agggactaaa aagagactat tatttaatct tcatcaaata tttaaattca
     7441 aggagaagta aaatgaaaaa aagaattaat aagaaagcat ctgtttttct agttgcaagt
     7501 gttttcagtt ttagctttgc tactacagct agtgtcgtta acgcagtaac ggcacaccct
     7561 gctccaagtc ccattattga tgtatgggaa tatggtgtaa atgataacta tggttattcg
     7621 aattactttg ttagttctcc aagtaatatt ggatcaaaat cttcagtaac gaatttttgg
     7681 ggaacagtta aagctcagga taaaaaagat tatggatggg catattcaag tgcaacaaaa
     7741 tcttggaacg atgttcgctt aaatgcatat tgggattatt atagatttta aaaataattt
     7801 atgaaaacaa gagacccaat tataagattg ggtctcttgt aatatggtaa ttgcttatga
     7861 aattaaaatt atgtatcatt ggattcttct tttgtttgat tgctacaatt ggtctggtca
     7921 ctattagtga taccgaaatc cccatacctt taccaattga tggagctttt tctatccaag
     7981 gaaaaagtaa tctttctaat aacgaaatat acgaaatggt tcgtgactta tcaaaaacgg
     8041 aaaaggttac catttacaag ccaatcgttc agagttcggg tcagttgaag tatgtaaatt
     8101 ttgatgatgt aaataatgaa caattaaagt cagcaccaat agtagggatg tattacacac
     8161 ttgggaaaat ggatgtagac agtttgaaac cacttacgat gacgggacta caaacagtct
     8221 atatggctta tccttggtat ataggaggaa tattacaatt cactggaact ttaagaatac
     8281 tgttaatggg ttcaatttat ttaactttat tagttgtttt atttgttgtt aggacgaggc
     8341 agatcaaaga aggagtgata cgacgttctt tgggcttgcc tatatacgac ttaagaagag
     8401 agtatggcat ttctcttatt tttgaactga ttatgatggc tttattgatg atttcttaca
     8461 gttctttttt gggtaatggt ttcttcacct atagttctaa gttatttttc tctctgcttt
     8521 taacgaattt tatactattt caaatcattg atcttattac ttttgtttta ttttggttga
     8581 cgattcagat tgaaaagcct attgaaatta ttaaaaacaa ggcaaaaaac aagcttattt
     8641 ttgtcgtatg gcttgctatt atttcgatta tcatccttgt ctcaggagtt tttttacaag
     8701 aaacaaagag tagtcaatct agtattaaca tacagataca gaatttagta ccatgggata
     8761 cagtaaaaga ctggagaagg attgagttcc ttggaattga aagtaactct actaaaaata
     8821 gagaagttaa tgattcagat ggtcagtatc tacagatagt tgctgcctta aaaaacttag
     8881 atttcttata tatagaacgg tcttcagcat atgttccaga tttcatgaaa acttcacatg
     8941 ttatagaaaa tttttctaaa caattagaaa atgacgggat aacgaatcca gaaataaata
     9001 aagagttaat ttatatcaac caaacaggtg ctaacctaca aaataaagtg aatggaacaa
     9061 actatcatct tttagataat aagatagcaa ccatctatat tcctgagaag tggaaagaaa
     9121 accagaaatc tattgagaat acagttgtag cagaacaatt tattggaaca aactatacaa
     9181 gagaacagct tgcagttcaa ataattcctg atggggaaaa aattttttat tttaatgagg
     9241 atgctgataa taatcttaaa atgaaagata ttttaccgct ggcaaatgta gcagatagca
     9301 aagataatat agttgttgtg ttagatacgg acaaaatgat ggaaaataat aagttttctt
     9361 tggctagtaa catactatat aaatctcttt ttagtcctga agcggtaaaa aaaataaatg
     9421 agatgactgt cctgttgaat ttctcaatga atccagtaga tgtttaccaa attgtgaaat
     9481 taaagattca atccttagag caccaaattt tactttcaca aatcttgcag aagataattt
     9541 acagtattgt ctttatactc atttatcaat atgtccaact ttttattact ctaaaacaga
     9601 atgaatatgt gaaaaaaatc attttgggtc tgtcaaaaac atatatagca atttcaagtc
     9661 tcaaatattt tatgatgact attacaatgg ttattctatt tacatttctt atgacagggc
     9721 aaatagagtt gctatatatt ggagcggctt ctctgctagt tttgatgttg tcaatcataa
     9781 tgagttttag aaaattatct gaaagctaca ctaaaatttt aaaaggagat gaatcatgac
     9841 aattgacctt ttgaacgttt caaaaagttt cggctcaaag aagatcttta cagacttaaa
     9901 tttaatattt gaatctggaa aaagctatgc attgattgga ggttctggct ccggtaaaag
     9961 tacccttctt aatattatag gaagattaga aaaaattgac agtgggaatg ttttagttga
    10021 taaacaagat atttggaaga taaaagaaag aacttttttt aaaaatactg ttggatatgt
    10081 atttcagaat tattctttaa tagataacaa aacagtgtat gataatctga gccttatcac
    10141 taaagacaaa aaaacaataa ctgacgtact tgaaaaagta ggactgtcaa gtgactattt
    10201 acaccaaaaa atatatgaat tgtctggagg gcaggctcaa cgtgtagcta ttgccagaat
    10261 gttaatgaaa ccacgtaaaa ttatcttagc agatgaacct acaggagctt tagatggtga
    10321 gattggaaaa gaaattattc gtttactatt gaatgaaaca gctgaagata aatatgtcat
    10381 tatagcgaca catgatccag ctgtctataa cgaagttgat gtgataattg acatgaaaga
    10441 tatagggtat aaggtatgaa aaagaaaatt tatattgctt tgatctttgt aactggggta
    10501 ctcgccattt tcttttttgg aaaacaaatg attacaaaag aaaatatcaa taagccaacg
    10561 gtagagttaa caatctatac gctttcttct agtgatacag aaaaatggaa taaagtgaga
    10621 caagtagaaa cggaagaagc tatatacttc ataactgtga aagaagtatc atcttcagaa
    10681 gaagtatttt caaacatcat tgcaaatgga gctgctacgg ggttcggagt tcgtgaagaa
    10741 gaagtgaaga aattcaataa tggtttagga gacaccatag aggactctaa gcataataaa
    10801 ctaattgaaa tagaattttt tactttttct gatgatggcg cgggatttgt ggtagcaaac
    10861 tttgactacg gtaaagaaga gttgaattct cagaaaaaa
//
LOCUS       DAVLCS010000057        10803 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLCS010000057 DAVLCS010000000
VERSION     DAVLCS010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10803
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.057"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            179..676
                     /locus_tag="VXC78_001887"
     CDS             179..676
                     /locus_tag="VXC78_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV0583902.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            676..2331
                     /gene="dnaX"
                     /locus_tag="VXC78_001888"
     CDS             676..2331
                     /gene="dnaX"
                     /locus_tag="VXC78_001888"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV0583903.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2359..2553
                     /locus_tag="VXC78_001889"
     CDS             2359..2553
                     /locus_tag="VXC78_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV0583904.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2703..3473
                     /gene="sufC"
                     /locus_tag="VXC78_001890"
     CDS             2703..3473
                     /gene="sufC"
                     /locus_tag="VXC78_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV0583905.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3501..4763
                     /gene="sufD"
                     /locus_tag="VXC78_001891"
     CDS             3501..4763
                     /gene="sufD"
                     /locus_tag="VXC78_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV0583906.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4774..6000
                     /locus_tag="VXC78_001892"
     CDS             4774..6000
                     /locus_tag="VXC78_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0583907.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPLKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5987..6427
                     /locus_tag="VXC78_001893"
     CDS             5987..6427
                     /locus_tag="VXC78_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV0583908.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6481..7893
                     /gene="sufB"
                     /locus_tag="VXC78_001894"
     CDS             6481..7893
                     /gene="sufB"
                     /locus_tag="VXC78_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV0583909.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFGDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8124..9365)
                     /locus_tag="VXC78_001895"
     CDS             complement(8124..9365)
                     /locus_tag="VXC78_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV0583910.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9468..10577
                     /locus_tag="VXC78_001896"
     CDS             9468..10577
                     /locus_tag="VXC78_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0583911.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT         3202 a         1970 c         2346 g         3285 t
ORIGIN      
        1 tgagttgttt tgttgctttt cattataggt catatgggac tttttttcta cacaaaatag
       61 gctccataat atccataggg gatttaccca ctacaaatat tatagagccc aaaatccttt
      121 gtttactaaa caagggattt ttcttttgtc tctgctcctt ttttgatata atagttctat
      181 gttaaaatca gaaaaacaat cacgttatca aatgttaaat gaagaattgt ccttcctatt
      241 ggaaggcgaa accaatgttt tggctaatct ttccaacgcc agtgctctca taaaatcacg
      301 ttttcctaat accgtatttg caggctttta tttgttcgat ggaaaggaat tggttttagg
      361 ccccttccaa ggaggtgttt cctgcatccg tattgcacta ggcaagggtg tttgtggtga
      421 ggcagctcac tttcaggaaa ctgttattgt tggagatgtg acgacctatc tcaactatat
      481 ttcttgtgat agtctagcta aaagtgaaat tgtggtgccg atgatgaaga atggtcagtt
      541 acttggagtt ctggatctgg attcttcaga gattgaggat tacgatgcta tggatcgaga
      601 ttatttggaa caatttgtcg ctattttgct tgaaaagaca acatgggact ttacgatgtt
      661 tgaggaaaaa tcttaatgta tcaagcactt tatcgaaaat atagaagtca aaacttctcc
      721 cagttagttg gtcaagaagt tgtggctaag actcttaaac aagcggtgga gcaagagaaa
      781 ataagtcacg cttatctttt ttctggtcct cgtggaacgg gaaaaaccag tgttgctaaa
      841 atctttgcca aggctatgaa ctgtcccaat caagtgggtg gcgaaccttg caataactgc
      901 tatatttgtc aagcagtgac ggacggtagt ttagaagatg tcattgaaat ggatgcagct
      961 tctaataatg gggtagatga aattcgcgaa attcgtgata aatctaccta tgcgcctagc
     1021 cttgctcgtt ataaggttta tatcatagat gaggttcaca tgctgtctac aggggctttt
     1081 aatgccctcc taaagacgct ggaagaacca acacagaatg tagtctttat tttggccact
     1141 actgaattgc acaagattcc tgctactatt ctatcccgtg tgcaacgttt tgagtttaaa
     1201 tcaattaaga cacaggatat taaggaacat attcactata tcttagaaaa agaaaatatc
     1261 agttctgaac cagaggctgt ggaaatcatt gccaggcggg cggaaggtgg aatgcgggac
     1321 gccttgtcta ttttggatca agccctgagt ttgacacagg gaaatgagct gacgactgct
     1381 atctctgaag aaattactgg caccattagc ctatcagcct tggatgatta tgtggcggcc
     1441 ttgtctcaac aggatgttcc caaagctttg tcttgcttga atcttctttt tgacaatggt
     1501 aagagcatga ctcgttttgt gaccgatctt ttgcactatt taagagactt gttaattgtt
     1561 caaacagggg gagaaaatac tcatcatagt tcagtctttg tagaaaattt ggcacttcct
     1621 caaaaaaatc tgtttgaaat gattcgctta gcaacagtga gtttagcaga tattaagtct
     1681 agtttgcagc ccaagattta tgctgaaatg atgaccgtcc gtttggcgga aatcaagccc
     1741 gaaccagctc tatcaggagc ggttgaaaat gaaattgcta cgctgagaca ggaagttgcc
     1801 cgtctcaaac aagagctttc taatgtaggt gcggttccta aacaagttgc accagctcct
     1861 agtcgaccag ctacgggcaa aacagtctat cgtgtcgatc gcaataaagt gcaatctatc
     1921 ttacaagagg ccgtcgaaaa tcctgattta gcacgtcaaa atctaattcg tttgcagaat
     1981 gcctggggag aggtaattga aagtctaggt gggccggaca aggctctgct agttggttct
     2041 caaccggttg ctgccaatga acaccatgct attcttgctt ttgagtctaa cttcaatgct
     2101 ggtcaaacta tgaaacgaga caatctcaat accatgtttg gtaatatcct cagtcaggcg
     2161 gcaggttttt cacctgagat tttagctatt tccatggagg aatggaaaga agttcgcgca
     2221 gccttttcag ccaaagccaa atcttctcaa actgaaaaag aagtagaaga aagcctgatt
     2281 ccagaaggat ttgaattttt ggctgataaa gtgaaggtag aggaagacta aagaaagatt
     2341 tcatgataca ataagtttat gaataaacaa caatttatta ttatggcgct gtttacagct
     2401 gctgagacct attttttcaa tgaagcctgg atgactggcc gctatattat ggcagccttt
     2461 tgggcaattt tactctttag aaatttccga gtcagttatg tgatgggcaa aatcgttgat
     2521 gtcatcgatc agcattttaa taggaaagac tagccctcag cttccagaca aaatcaaagc
     2581 cttttaggct tttttttgtt atactagaaa agtatattta tagaattttt gctctatttc
     2641 tggggaaatc agacgttttt ctagtaagta ctgtaaaagt tttgaaaaag aaaggaacta
     2701 tcatgtcagt attagagatc aaagatcttc acgttgagat tgaaggaaaa gaaattttaa
     2761 aaggggttaa cctgaccctg aaaacaggag aaattgccgc tatcatggga ccaaatggta
     2821 caggtaaatc gactctttct gccgctatca tgggaaatcc aaactatgaa gtaactaaag
     2881 gtgaagtttt gtttgatggc gtaaacatcc ttgagttgga agtggatgag cgtgcgcgta
     2941 tgggactttt ccttgctatg caatacccat cagaaatccc tggaattacc aatgctgagt
     3001 ttcttcgtgc cgctatgaat gcgggtaaag aagatgatga gaagatttca gttcgtgagt
     3061 ttattactaa gctagatgaa aaaatggaat tgcttaacat gaaagaagaa atggcagagc
     3121 gttacctcaa cgaaggcttc tctggtggtg agaaaaaacg caatgaaatt cttcaacttt
     3181 tgatgttgga gccaacattt gctcttttgg acgagattga ctcaggtctt gatattgacg
     3241 ctcttaaagt tgtgtctaaa ggtgtcaatg ccatgcgtgg tgaaggtttt ggtgctatga
     3301 tcattactca ctaccaacgt cttttgaact atatcacacc tgatgtggta cacgtgatga
     3361 tggaaggtcg tgttgtcctt tctggtggtc cagaattggc tgcgcgtttg gaacgtgaag
     3421 gatacgcaaa attagctgaa gaacttggct acgactacaa ggaagaattg taattccctc
     3481 gtatctttta ggagaagtaa atgactagag aaaatattaa acttttttca gaaatgcacg
     3541 ctgaaccaag ctggttggct gatctccgtc aaaaagcttt tgacaagatt gagactttgg
     3601 aattaccagt tattgagcgt gtcaaattcc accgttggaa tctgggtgat ggaacgatta
     3661 cagaaaatga gccatcagca aatgttccag atttcacagc tttagatcat cacttgaagt
     3721 tggtgcaagt aggaactcaa actgttttcg aacaaactcc agttgagtta gctgaacagg
     3781 gtgttgtctt cacagacttt cactcagctt tagaagaaat tccagagctg atcgaagaat
     3841 tcttcatgtc atctgttaag tatgatgatg acaagttggc ggcttaccac acagcttact
     3901 ttaacagtgg tgctgtactc tatattccag ataatgtaga aatcacagag ccaattgaag
     3961 gaattttcta ccaagatagc gatagcaatg tgccgtttaa caagcatatt atgattatcg
     4021 ctggtaaaaa ttctaagatt aattatctgg agcgtttaga gtcacgcggt gaaggaagtg
     4081 ccaaagcaac tgctaatatc acagtagaag tgattgcacg ttcaggtgcg caagtcaagt
     4141 ttgctgctat cgaccgtcta ggtgaaaacg tcactgccta cattagccgt cgtggtaaat
     4201 taggcaacga tgcaagtatt gactgggcta tcggtgtcat gaacgaagga aatgtcgttg
     4261 ctgattttga tagtgacttg attggtaatg gtagccatgc tgacctcaag gttgtagctc
     4321 tttcaagtgg tcgtcaggta caagggattg atactcgtgt aactaactat ggctgcaact
     4381 ctatcggaaa tatcctacaa catggggtta tccttgaaaa agcaactttg actttcaatg
     4441 gtatcggcca catcatcaag ggtgctaagg gagcagatgc ccaacaagag agccgtgttc
     4501 tcatgctttc agaccaagcg cgttcagatg ctaacccaat tcttttgatt gatgaaaatg
     4561 acgtcactgc aggacatgca gcctctattg gtcaggtaga tccagaagat atgtactacc
     4621 tcatgagtcg tggattggat aaggcaactg cagagcgttt ggttgttcgt ggtttccttg
     4681 gatctgttat cgtggagatt ccagtcaagg aagttcgtga tgaaatgatt gcaactatcg
     4741 aagagaaatt gtcaaaacgc taaggggaag cctatgttag atgtagaagc gattcgcaag
     4801 gattttccaa ttttagatca gattgtcaat gatgaacctc tggtctatct ggacaatgct
     4861 gcgacgacac aaaaaccact agtagttctg aaagctatta acagttacta tgagcaggac
     4921 aatgccaatg ttcaccgtgg tgtccatacc ttagcggaac gagcgacagc ttcttatgaa
     4981 gctgctcgtg aaaccattcg taagtttatt aatgcaggct ctacaaagga agttctcttt
     5041 accagaggaa cgacaaccag ccttaactgg gtggcacgct ttgctgagga aattctcact
     5101 gagggagacc aggtcttgat ttcagtaatg gaacaccatt ctaatatcat tccatggcag
     5161 gaagcttgtc gaaagactgg agcagagctt gtctatgtct atcttaaaga cggtgccttg
     5221 gatatggagg atttgcgagc taaattgact gataaggtta aatttgtttc cctagctcat
     5281 gcctccaatg ttcttggtgt ggtcaatccg atcaaggaaa tcactcaatt agcccaccaa
     5341 gttggggcaa tcatggtagt ggatggtgct caatctacac ctcatatgaa gattgatgtc
     5401 caggacttgg atctggactt tttcgccttt tcgggtcaca agatggctgg tccgactggt
     5461 atcggtgtcc tttacggcaa agaaaagtat cttgagcaaa tgtctccagt agaatttggc
     5521 ggcgagatga ttgattttgt ctacgagcaa tctgctagtt ggaaggaatt gcctttgaaa
     5581 tttgaggctg gaacgccaaa tatggcagga gctattggac ttgcgactgc agttgattat
     5641 ctggaaaaga ttggtatgga tgccgttgaa gctcatgaac aggaattgat tgcgtacgtc
     5701 tatccaaaac tgcaggcaat tgagggattg accatttacg gttctcagga tttggctcaa
     5761 cgttcgggtg ttattgcctt taacctaggt gatctccatc ctcacgatct tgcgacggct
     5821 ctggattatg aaggagtggc tgttcgtgct ggtcaccatt gtgcgcaacc cttgcttcag
     5881 tatttggaag tcccagcaac agctcgtgca agtttttata tctataatac caaggcagat
     5941 tgcgacaaac tagtcgatgc cctacaaaag acaaaggagt ttttcaatgg cactttctaa
     6001 actagatagc ctttatatgg cagtggtagc agaccattcg aaaaatccac atcaccaagg
     6061 gaagttagaa gacgctgagc aaatcagtct caacaatccg acttgtggag atgtcatcaa
     6121 tctctctgtc aagtttgatg cagaggaccg tttggaagat attgcttttc taaattcagg
     6181 atgcacgatt tcaactgctt ctgctagtat gatgacagat gccgttttag gaaaaaccaa
     6241 acaagaaatt ttagaactgg cgactatttt ttctgaaatg gttcaagggc aaaaagatga
     6301 gcgtcaagac caacttggag acgcggcatt cttgtcaggt gttgccaaat tccctcaaag
     6361 aatcaagtgt gcaaccctag cttggaatgc ccttaagaaa acaattgaaa atcaagaaaa
     6421 acagtaagac aagtttcttt tgtcttatga attattagaa atgaagaaag aaaggatatt
     6481 atggctgaag aaagagtaga accaaaacca attgaccttg gtgaatataa atttggtttc
     6541 catgacgatg tagagcctgt cttatcgaca ggaaaaggac tcaacgaagg tgttattcgt
     6601 gaattatctg ctgctaaggg tgagcctgag tggatgttgg agttccgttt gaagtcttat
     6661 gaaaccttca aaaaaatgcc catgcaaact tggggagcag acttgtcaga gattgacttt
     6721 ggtgacttaa tctactacca aaaaccatct gacaaaccag cccgttcttg ggatgatgta
     6781 cctgaaaaga ttaaagaaac ctttgaacgt atcgggattc cagaagctga acgtgcttat
     6841 ttagcagggg cttctgccca gtacgagtca gaagtggttt accacaacat gaaggaagag
     6901 ttccaaaaat taggtattat ctttacagat acagattccg cactcaagga atacccagac
     6961 ttatttaatc aatactttgc gaagttggta ccgccgacag ataacaagtt ggcagccctc
     7021 aactcagcag tatggtcggg tggaactttt atctacgtgc caaaaggtgt caaggtagat
     7081 attccacttc aaacttattt ccgtatcaat aacgaaaata taggtcagtt cgaacgtacc
     7141 ttgattatcg ttgatgaggg agcaagcgtc cactacgtag aaggatgtac agcaccaaca
     7201 tattcaagca atagcttaca cgctgccatt gtagaaattt ttgctttgga cggagcttat
     7261 atgcgttata caactatcca aaactggtct gataacgtct ataacttggt aacaaagcgt
     7321 gctaaggctc aaaaggatgc cactgttgag tggattgatg gaaacttggg tgccaaaacg
     7381 actatgaaat atccatctgt ttaccttgat ggagaaggag cgcgtggtac catgctctct
     7441 atcgcctttg ctaatgcagg gcaacaccaa gacacgggtg ctaagatgat tcacaatgct
     7501 ccacatacca gctcgtctat tgtgtctaaa tccatcgcta aaggtggagg aaaggttgac
     7561 taccgtggac aagtcacctt taacaagaac tctaagaaat ctgtttccca cattgaatgt
     7621 gataccatta tcatggatga cttgtcagca tcagatacta ttccatttaa tgaaattcac
     7681 aactcgcaag tggctttgga acacgaagcc aaagtatcta agatttcaga agagcaattg
     7741 tattatctca tgagccgtgg attgtcagaa tctgaggcaa ctgaaatgat tgtcatggga
     7801 tttgtagaac cctttacaaa agaacttcca atggaatacg cagttgagct gaaccgcttg
     7861 attagctatg aaatggaggg atcagttgga taaaatttga ttttatactc ttcgaaaatc
     7921 tcttcaaacc acgtcagcat cgccttaccg tatgtatggt tactgacttc gtcagtttca
     7981 tctacaacct caaaacagtg ttttgagcaa cctgaggcta gcttcctagt ttgttctttg
     8041 attttgagta ttagatttac tcaaaatcaa ggattttgaa gatgaacttg tatcaaaaaa
     8101 tcgcggttta aaatcgcgat tttttataat ttctcgttaa caaagcggac aaactgattc
     8161 caccaaactt ttaagaagaa ggctttttca attttcttgt ctgctaccat ttcgaaacta
     8221 gggcgctctg tggtgatgta accttgacca atcaagtcct tgtcttcata agtcaaatgg
     8281 ccaaccactg ttccagcttc aagtggtgct gggattgctt tggaatcagg tgtgaattga
     8341 acagattggg aagattgatt cccaacacgt tcgattagat agatatcctc tggagccact
     8401 gcagttactg tatcttcttt tccatcttgt acaggggctt tgctatcttg ataggcatcg
     8461 ccttgttgaa cgattttgcg aagtgtaaat gtagaagaaa tataatccat tagggaagat
     8521 gtagctgtaa atcgagcgta aggattattg tcttgatgat ctgcatttaa aacaactgtg
     8581 atgactctca tgcctttttc gacagtagta ccaacaaaag actctccagc cttatctgtt
     8641 gttcctgttt ttagcccatc aaaaccacca cggtaagcag gcataccttc taacatgtag
     8701 ttggttgaag tgattgtcat cccagcaaaa gtagaagaag gttttttggt gatttctaag
     8761 acttgtgggt attttttgat gaggttgcga gcaacgatag cgacatcata agcactaagc
     8821 ttattttcct catctttttt agaacctggg taaatgttat cccctagagt ttcattgtta
     8881 agacctgtcg tattgacaac agtggcatcc tgaattcccc attccaagag ttttgcccgc
     8941 atcatatcga cgaaatcttt ttctgagcca gcaattttct cagctagggc aatagcggcg
     9001 ctgttggcac tagataccag agttgcttca agcaactctt cgacagtata attacgggcc
     9061 tccataggaa tattactggc ttcagaattt gtcgtcaatt gataaggata atcagaaata
     9121 tctacaggag tggagagggt aatacttccg ttttccaaag cttcatagac cagataaaca
     9181 gtaatcaatt ttgttatgga agcaatttcg acaggttgcg ttgcatcctt ctcatagaga
     9241 attttaccag tatttgcctc aacagcaatc gcatgtttag cggcaatggt aaaatcttga
     9301 gcaacagcag tagaagcacc ccctaaaaga gagacagtta acaaagttaa aaatattttt
     9361 ttcatagtag tcttattcta tcataaagaa aaaaaatatt cttgctttaa taattcatct
     9421 gttaagcttt ttgaaaatat ggtaaaataa agtgagggag gtaactcatg tttcgtagaa
     9481 ataaattatt tttttggacc acagaaattt tactcttaac catcatcttt tacctatgga
     9541 gacagatggg gtctttgatt aacccttttg ttagcgtgct taatacaatt atgattccat
     9601 ttttattagg aggctttctt tattatttga caaaccctat tgttactttc ttaaataaag
     9661 tctgtaaact caatcgtttg cttggtattt taattacctt gtgtactttg gtctggggaa
     9721 tggtcatagg tgttgtctat ctcttaccta ttttgattaa tcagttatct agtttgatta
     9781 tatctagtca aactatttat agtcgagtac aagacttaat catagactta tctaattatc
     9841 ctgcgctcca gaatttggat gtagaagcta caattcagca gttaaactta tcctatgtgg
     9901 atattcttca aaatatccta aatagcgtat caaatagtgt ggggagcgtc ttgtcagctc
     9961 ttatcagtac tgttttgatt ttgattatga ctccagtttt tttggtttat ttcttattag
    10021 atggacataa attcttgccc atgcttgaaa gaacgattct aaagagggat cgcttgcata
    10081 ttgcaggctt attaaagaat ttaaatgcga cgattgctcg ctatattagt ggagtttcga
    10141 ttgacgcaat cattataggt tgtttggctt atattggcta tagtattatt ggtttaaaat
    10201 atgctttagt ttttgccatt ttttctggtg tagccaattt aattccttat gtggggccaa
    10261 gtattggttt gattcctatg atcatcgcaa atatattcac tgatccccat agactgctga
    10321 ttgcagtgat ttatatgctt gttgttcagc aggtagatgg caatatctta tatcctcgaa
    10381 tcgtaggaag tgttatgaag gttcatccaa tcacgatttt agttttactt ttgttgtcaa
    10441 gcaatatcta tggtgtagtt ggaatgattg tcgcagtgcc aacctattct atcttgaaag
    10501 aaatttctaa gttcttatcc cgtttgtatg aaaatcataa aataatgaaa gaacgagaaa
    10561 gagaattagc taagtaaaag tcaggagaac cctgattttt ctttactgga agtggccttt
    10621 agattagaag actgaaaata agttaaagtc ttaaactaat tttcacagct aagaatagta
    10681 gaagttaatc tgataaaaat cgaaaaaacc agtggaattc tgtgtcaggg taagttccac
    10741 tggttttcat agtctattaa agttcgaatg aaacctattt atagtagatt gaaactagaa
    10801 tag
//
LOCUS       DAVLCS010000058        10672 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLCS010000058 DAVLCS010000000
VERSION     DAVLCS010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.058"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(31..1455)
                     /locus_tag="VXC78_001897"
     CDS             complement(31..1455)
                     /locus_tag="VXC78_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0583912.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2000..4279)
                     /gene="pulA"
                     /locus_tag="VXC78_001898"
     CDS             complement(2000..4279)
                     /gene="pulA"
                     /locus_tag="VXC78_001898"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV0583913.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4391..6349)
                     /gene="ligA"
                     /locus_tag="VXC78_001899"
     CDS             complement(4391..6349)
                     /gene="ligA"
                     /locus_tag="VXC78_001899"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV0583914.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6442..7620)
                     /locus_tag="VXC78_001900"
     CDS             complement(6442..7620)
                     /locus_tag="VXC78_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0583915.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMVGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLQSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7700..8563)
                     /locus_tag="VXC78_001901"
     CDS             complement(7700..8563)
                     /locus_tag="VXC78_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0583916.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8566..10467)
                     /locus_tag="VXC78_001902"
     CDS             complement(8566..10467)
                     /locus_tag="VXC78_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0583917.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKYSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYIEKRATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3201 a         2359 c         1903 g         3209 t
ORIGIN      
        1 accaggaaaa caatttcctg gttttacacg ttatttcaca tcaaaaacaa tggatttgac
       61 atttgtcatc gcttcaatgc tatatttaat tccttgcact ccagctccag aacctttgac
      121 accaaggaat gggaaattat ctggaccacg ctgggtttta ttattaatgt ggactgtacc
      181 tacttcaagt ttttcagcaa tttcaaaggc ttttttgaaa tcatttgtaa agactgatga
      241 ttgaaggccg aattcagatt cgttggcaaa ggcaatagct tcctctacac tagccacacg
      301 aatgattggt aaaacaggac caaatggctc ttcccatgcc actttcatat cttttgtaac
      361 ttggtcaaaa agcactggcc agagaagatt gccctcacgt ttgattggtg taagagcctg
      421 agcttctttt tcttgtgcat cctcaatcaa gccccaaatg aagtcggctg aagcattgtc
      481 aataacaggt gtaatatcag cattgtcaaa tggatcacca actgttaatt tagaaacttc
      541 ttcctgaagc aaagtagcta atttatctgc tacactttcg agaacaatga cacgtttaat
      601 ggccgtgcaa cgttgtcctg agtagctaaa ggctcccgca acaatttgct tggcagcatg
      661 ttccaaatct gcatcttcta gtacaagagc tgcatctttc ccaccaagtt ccaacatgat
      721 aggacgcata ccagctaaac gaccaatacg ttctccaata ggagttgaac ctgtaaagtt
      781 gatgaagttg acttctttgt gctcaatgat ataatcccca atttctgaac cacgacctgt
      841 aatggtgttg aaaacacctg ccggaatccc tgcttcttca aatgctttag ccaacaagag
      901 tccagaaatg gaaccttgtg ttggtggctt aaacatgacc acattccctg caatcaaggc
      961 aggtgcaatt ttagaagcag ataaattaac tggataatta aagggagcaa tcgctagcac
     1021 gataccaact ggttcacgac ggacaacagc cagtttgttt ttacttgctg cctcaaaacc
     1081 accaccttcc attgcttgtc cagtgatacg gagaccttcc tcagcagcat aacgaatcaa
     1141 gtctgctgta cgcactactt ctccaattgc tgctttaatc ccttttgcta cttctttggc
     1201 aaggatagta ccaatttctt ccttatcgcg ttctaaaata gctgctgttt tatgtaaata
     1261 agccgcacgt tcaactgctg ataaagctcg ccatgctggc agggctgcac gcgcagcttg
     1321 catagcctca tcagcttcag tctgagtcat ggctggaact gtacccaatt cttcttgatt
     1381 gattggtgaa taaatcgtaa tttcttgttc agatgatttc cattttccat ttactaaatt
     1441 ctgatatctt gtcaaattct tgtcctcctg aaaatgatta agatatattt taccaaattt
     1501 tcagaaaatc acaacccttt ttgcaaaatt tttgagatta ttttcacaaa cttgattttt
     1561 caaagtatac tcaataaaaa taaaaaaaat ccactacgtc aaggcgaggc taatgtggtt
     1621 tgaagaaatt ttcgaagagc gtgaatgagt atcatctata gtaaaataaa aaaactgaac
     1681 aatttggttg gggacagcca aaccaatttc tcacaatgtt tcagaaacaa gggtgtgcta
     1741 ctccaatttc agcctactat aactgtcata gattgctgaa acaaagtcta ggtaaaagtc
     1801 ttcataataa aaagacctcc tatcaagtgt tcaaaaactt tgataggagg tcttgttttg
     1861 tgaaaatatt tatcaaattt tctatacaag tgagctgtta gccaggttct ttctattctt
     1921 tcaatttcaa tgaatggatt ttttactaat actcataact gggaatttgt ctgtgtaaaa
     1981 atagcgagat agatggtatt tataaaacac tcaagacagc tagactaata tcatttaaaa
     2041 cattatcttc ttttgagcga ctgttggtta ccaacatagc taaatttcct gcattttcaa
     2101 attgataggg ttctgattta gcattcacaa ccaccaagag gtgttctttg ccgtgaactt
     2161 catagataag gtagccgcta tgttcaatcg cagaatgcac aaagacatga tggtaaattt
     2221 catcatagct agagtaagaa aaggcaccag tttttgtctt caatcggatg acttgacgga
     2281 taaactcaat actgtcttga cgctcattaa tcaagttcca gttcacttgg ttcacactgt
     2341 caggagcatt atagctattc atcgcacgct ctctatcatc atgggtcaac tcaccatttt
     2401 caccagtcgc aaccagtttg gtacgaccaa attcttgacc gatttccata aaggccatcc
     2461 cctgcatgag cagattcatg gctgtggcag tttcgacctt gcgcatgatt tgctctgaac
     2521 tttggtctgg atgaagggtt gccaataaat cgtgaagatt gtaattgtca tgggcttcta
     2581 catagttaag cacctgattt ggatgtgtat agcttcctaa ttcacgactt cctaggattg
     2641 ctttagctag aattggctct gtcgcagcac cactgacaaa acctgacttg atagcaccat
     2701 aaacttctcc ccctttgaca gcatcgcgct gattgtcatt aaagaaacca atatttggca
     2761 tctggtaggc attgtccttc ttggccttat cataaggggc aagacctgtt cccatatccc
     2821 atccttctcc atagaggata atgttggagt cgatttcatc caagctttga cgaatcatct
     2881 gcatggtctt gacatcatga atccccatca agtcaaaacg gaagccgtca atattatatt
     2941 cctgcaccca gtatagaaga gaatcaatca tatacttgcg aaacatttcg tgttcactgg
     3001 ctgtttcatt tccaacaccc gttccattct ggaaggtacc atctggattc atacgataat
     3061 agtaatcagg gactgttgtt tggaatggtg catcaacaac tgagaaggta tggttataga
     3121 ctacatccat aatgactcca atacccgcat cgtgataagc ttgaaccatc accttcaaat
     3181 cacgaatgac ctgagctgga tcatctggat tagttgaaaa actagtttct ggcgcgttat
     3241 agttttgtgg atcataaccc cagttgtagg ttacatttcc atcctcatcg tattctttat
     3301 gacggtctgc aattggttgc aattgaacat aattgtagcc cagcttcttg atgtaatcaa
     3361 aagcagttga ctggccgtat tggttaactg ttccagcctg agcagcaccc aagaaagttc
     3421 ctcgaagatg ttcatctaca cccgatgtag gtgatttagt caaatcacga atgtgcattt
     3481 cacagataac tgccttacat ggattttcca agcgccaagt agcctccgaa ccgtgcttaa
     3541 cctcgaagtt ttcaacttgc ttttctacat ggctcagaat agctgaacgt ttgccatcag
     3601 ggctggtcgc gattgtataa ggatcacgtg tcagtgtttg gtgatgaggg aattggactt
     3661 gatactgata agtcttacct accaaatctt cttcaacatc caaactccag acaccgattg
     3721 tattgtcctt atgattataa gagtagctat tgcctctttt catctcaaaa gtcttccaaa
     3781 cgggtgcatc attagcagct gattcataaa cgacaacttg cacttctgtc gctgtaggtg
     3841 accagaggga aaaatgagcc tgattgtcct ctacacggca acccaattct ccttggtaac
     3901 cccaatgatg atcaaaacta gcactgttaa tggccttatc aaaggcaaaa ggattttgat
     3961 ttttatagaa aggactggca atagcaggat tttcagagta ataaatccta tcatcgcctt
     4021 ccaaaatcca gacctctgtt aataggggat agtgattaaa acggatagaa tattctttac
     4081 tagtttgacc tgtatgaacc acaaaattca agctttctat aacatgtgaa cttgggtgtt
     4141 caaagctaaa taaagctcca aaataatctt ctttgtaggt tagcaaatca attcgttgat
     4201 cctgactttt tacaaaggag caagtgtcat attctccatt cttacgatgg taatgaatgc
     4261 gcatagggta gttatacatt ttttattttt cctttttact ttgtttctat ttcactaata
     4321 aatttttgtc aatctcgtct caattaacag acatagtcat attctctaaa ctctgttttt
     4381 aaacgatcca ttacaaactt tctagccatg cctcatctct gacctggata ccaagttctt
     4441 gtgctttttg cagtttactt ccagcgtctg cacctaccac gacgaggtcg gtctttttag
     4501 aaacactacc tgtcactttg gcacccagac tttcgagttt acttttagct tctgagcgct
     4561 tgagtcgttc caattttcct gtcaatacca cggtcaaacc tgacaaggcc gcatccgcta
     4621 ctaccgtctg tcctttatag tccagattga ccccagtttc tttcaattct ctgagcagaa
     4681 tttcagagcc ttctgtcgca aaataagtct gaagactttt ggcaatcacg ccacctagac
     4741 tttcaatact agccacttcc tctgaatctg cctgatacag attttcaatt gaatggaaat
     4801 attgaagtaa aagctgacta gccttgcttc cgacatgacg aattcccaaa ccaaataaga
     4861 gcttctcggc agaattttcc tttgatgctt ggatagcctg atacagttta gcagcggact
     4921 tttccttaac cccctctaaa aggaggaaat cctcttcttg caaacgataa atatccgcca
     4981 catccttgac taaattagca gcaaaaagct tctcaacaat agatggacca aggcctgtaa
     5041 tattcatagc atcacgagaa gcaaagtgaa tcaagccttc catgatttga gcagggcaac
     5101 gcggattgat acaacgtagg gccacttcat cttcaaagtg caacaagtca gagttacaac
     5161 ttggacagtt tgtagggata tctagttttt cttcagaaac ccgtttggac tctaccacac
     5221 gtaaaacggc agggatgatg tcaccagcct tatatacaat gaccgtatcg tcttttcgga
     5281 tatctttttc agcaatataa tctacattgt gcagggtcgc acggctaaca gtcgtaccgg
     5341 caagttgtac tggtgttaga ttagcagttg gagttacaac accggtacgg ccaactgtcc
     5401 agtcaactga taagagttga gcttcttttt cttcggcagg gaacttgtag gctactgccc
     5461 actttggagc cttaactgta aaaccaagtt cttcttgact tgctaggtcg ttgaccttga
     5521 ttaccactcc atcaatatcg taaggcagat tttcccgttc ctgtcctact tcttggataa
     5581 aattccagat ttcatctatg ttttcagcca agattcgctt aggattgacc acaaaaccta
     5641 gttgttctag gtacttcaaa cccttttctt ggctatcacg agttgaaggg ctggcttctt
     5701 gatagagaaa cgttgcaaga ttacgcttgg caactactgc tgtatccaac tgacgcagag
     5761 ttcctgctgc cgcattacga ggattagcaa attcaggctc tccattttct tggcgcactt
     5821 ggttaacttg gtcaaaggaa gcgcgtggca tgtaacattc cccacgaact gtgatatcta
     5881 gttcttctgg caaagtcaaa gggatgtcct taacacgctt gaggttttct gtgatatttt
     5941 caccaattga accatctcca cgtgttaccc cagcaaccaa aatccccttt tcataagtca
     6001 gcgagataga taagccatcg attttcagct cacaaatata ggtcggatga gccacttcct
     6061 tacgaacacg cgcatcaaaa gcatctagct cctcacgtga aaaagcatcc tgcaaactat
     6121 aaagaggata ctgatgactg tatttttcaa aaccatctaa aaccttgcca ccaacacgat
     6181 gagtcggact gtctgctagc acttgctctg gataagcagt ttctaactcg accaactcac
     6241 ggtaaaggcg gtcatactca ctgtctgaaa ccgagggatt atcgctggta tagtactcag
     6301 tcgcatagcg attgagcaaa gcgactaact cattcattct tttattcata agaccatttt
     6361 accataaaac aagccctcct cacaaacgag aagggcggaa aaaacactta gtttgaaatt
     6421 atttttgaaa ctcaagcaac cttatatcaa tttttcaaaa tgagttcgaa cataaataaa
     6481 cgatatacaa gacaagatga taacaccact tccaattatc aggaaagaag agagatgtac
     6541 actttgcaag actgtcataa atccttttgc aataggcata aatagaatag ctaaggtaaa
     6601 aattgtactc agtactctcc caagaaattc gctctcaacc ttggtttgta cttgagtaaa
     6661 aaagtgaata ttaaaaatcg tcataaacaa ttcacaaact aaatttccag aaaaggaaag
     6721 aaaagttgga agtggtaatc ccatcataaa aactccgaca cctgtcaaag ccagtaaaat
     6781 caaaagatta taaatattag ctttaatttt actagctaga agagccccaa tgatggaacc
     6841 aatagccccc atagttaaaa tacttgcata ggctccttct gacccgtaaa gctgattcga
     6901 aaagggaagt agaaattcaa aagctgcaaa aaagaaatta acgctggaag ctaccagcaa
     6961 aaggaagaaa atttcttgct gatgccagat atagtgtaac ccatccttga tatctacaaa
     7021 aatatctctc ccagtaaaag cctttttctc ttgaactttt gcttcctctt ttggaaggaa
     7081 agccactaga acaaaagcaa tgaaaaaagt cagcgagtct agcagtagcg tcatatggag
     7141 acttgcaaac tgtaaaacaa ggaaggaaag aacaggagag ctaacaccta caacctgcaa
     7201 aaccagctct aagcgagaat tatagatcac aatctcatct ttctccacca cttcagttat
     7261 gatagcttta ttggctgtgc gagaaaaggc aaaagcaata gcctgcacaa tgttagcaac
     7321 aatcaaagcg ccaaccatcc agctatcatt ccttatgaaa gaaatagcca gacaaagaat
     7381 cccacaaaca agatctgccg tcattaaaat cttacgacga gaaaaacggt ctgaaataac
     7441 tccgccaaag ggattgacga gaatagatgt gacgagctca gaaatctgat acattcctaa
     7501 aactgtctgt cctatagtcc ccatagaagc caaccagaca ctatttccat aatcatagag
     7561 catatttccc attttattga tagccccacg gctaatcaac tgcactgcat agcgattcat
     7621 attaaagctc ctctcaaatt ttgaaactat tgtatcaaaa ccgaaaggag ctttttattt
     7681 tttcccttat ttgagaaaat taacttttga caaatttttc gtagtgttcc tgataatagg
     7741 ctacttgctc tggaagacct aacacatcaa aaatatgcat ggcctcttgc atctgcttac
     7801 agccttcttt acactgtcct ttttgatata aggcaaaacc ttttaaataa tggaaaacat
     7861 tacgctcata aagcttaata cctttgtcaa taatcttctc tgtataagcc tcaaaatagt
     7921 tggcattata aaaagaagaa tgctctaaac aatgctggta acaattgagg gccaaaatta
     7981 acactaatct cttatggcga ctaatctctt ggtaaaattc ctccctctcc ataacttctc
     8041 taccaatccg agtgacatag tctacatcgt agaaactata gaggttaccg aaaagaatca
     8101 actcatacat ggtccattct tctgttttga agagataatc tgctacctta tccaaatcat
     8161 cctgcttcat atcataagtc gcatctcttt gacaaatcag accttgtagc aaaatccagt
     8221 tcagctcaaa ataaagggga gtcgtcgaac tcttagactt ttcaagttgt tctctttgaa
     8281 gcttttgaaa acctgcaata tcgtttgaat agtaaagtgg gataatctgt gccatcatag
     8341 acacatgttc atgattatga aaattccttg ccttatccat gaaattttcg attgttacat
     8401 gaatgttatc caaaatctca aagaaacggg agactgccag gtcagactcc ccaagctcaa
     8461 agcgagataa ctgagaggta gagcaggatt cgcctgctgc ttcctttaaa gaataatttc
     8521 cacttgttcg aaattcacga aatacttttc caagatgttc catttttaca cctgctctga
     8581 taattcttcc cactcaagca tagcttcttc ctgacgatgg ctgattttgt ccagctcagc
     8641 ctgtaattcc atgagtttgt cggcatcgtt tgtttccaac atttgttcag aaatggcttg
     8701 gctttgactt tctagctctt caatttcagc ttctagactt tcgatttgtc gcatgagttt
     8761 gcgaacttct ttttgacttt ctttctgggc ctgatagtca ttgactggac ttgcttcctt
     8821 tgcttgattg ctagttgaag cttcctcagt ctgactcatt tctgctgttg ctctcttctc
     8881 aatatagtag tcgtaatctc caaggtagag agttgaacca ttctcagaca attccaaaac
     8941 atgagttgcc acacgattga taaagtaacg atcatgactg acaaaaagca aggtaccatc
     9001 aaagtcaatc aaggcatttt ctagcacttc cttactatca atatccaaat ggttggtcgg
     9061 ctcatccaga atcaaaaagt tattgttttc catagacaat ttagctaaaa gcaaacgagc
     9121 tttttcgcca ccagatagca tgccgactga ttttttaaca tcatctcctg agaaaaggaa
     9181 ggctccaaga cggttgcgga tttcaacttc tggtgtcagt ttgaaatcat tccagagttc
     9241 atccagcacc gtattacttg gtgtcagctt gctttgggtt tggtcatagt aaccaacctc
     9301 aacattagcg ccaaagcgct tttcaccttt gataaaagga atctggtcca caatagactt
     9361 gataaaggtt gacttgccga taccatttgg accaacgata gcgacagcat tcatcttacg
     9421 aagatctagg ttgataggtt gtgacaaaac ttccccgtca taaccaatag cagtattttc
     9481 aacagtcaaa acaacattgc ccgacgtttt ttcagactgg aaggtcatgt tggctgcttt
     9541 cttgccagct tcaggcttgt ccaaacgctc cattttttct agttgtttac ggcgagattg
     9601 agcacgtttg gtcgttgaag cacgaactag attgcgattg acaaagtctt ccagagcagc
     9661 gatttccttc tgttgctttt catagttttt tgcctcagta gctagctttt gctccttcaa
     9721 ctcaacaaaa cgagagtaat tccccacata gcgatccaag gaatacttgg tcaaatctag
     9781 cgtaattgtc gcaaccttgt ccaagaaata acggtcgtgg ctgacgataa tgagggcacc
     9841 gctatagttt accaagtaat tctctagcca ggagatggtt tcaatatcca agtggttagt
     9901 tggctcgtcc aagaccaaga gattgggctt ttcaaggagc attttagcta gagccaaacg
     9961 agtattttga ccaccagaaa gctcagcaat tttcatctgc cacatagact cgtcaaactt
    10021 gaatccattc aaaatcgctc gaatatcagc ttcataggta aagccacctg cttggcgaaa
    10081 attttcagat aagcggtcat aatctgacat cagtttatcc aaatcctcac cagacttttc
    10141 acccatctcc agctccatct gacgcagttg tttatctgtc cgacgtaagt catcaaagac
    10201 atgaagcatc tcatcataga tggtattttc agactcaaaa cggctatctt gagctaggta
    10261 agacagagaa atatcttttt tcttattgat ttctccacta gttggctcct cttctccaac
    10321 taaaatcttc aaaagagtag acttacctgc accatttttc ccaacaaggg caatccgatc
    10381 tcgttcatca acctgcaggt tgatattatc gaaaagaacc tctcctgcaa aagaacgttc
    10441 aattttatta gcttgtaaaa taatcataca agtagtatag catgtttccc taaggcattc
    10501 aagataatcg taagtctttt agtacaactt ttataacata aaataaacta aattatgtat
    10561 attttatatt agattccttc actatcttgt tggattttct aaccagctaa tcttgtttca
    10621 aatagttatc gcacaagcct attatttaat tcttttcatt atttacgtac gc
//
LOCUS       DAVLCS010000059        10664 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLCS010000059 DAVLCS010000000
VERSION     DAVLCS010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10664
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.059"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(8..1222)
                     /locus_tag="VXC78_001903"
     CDS             complement(8..1222)
                     /locus_tag="VXC78_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0583918.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1378..1672)
                     /locus_tag="VXC78_001904"
                     /pseudo
     CDS             complement(1378..1672)
                     /locus_tag="VXC78_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1834..2286
                     /locus_tag="VXC78_001905"
     CDS             1834..2286
                     /locus_tag="VXC78_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV0583919.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2321..3709)
                     /locus_tag="VXC78_001906"
     CDS             complement(2321..3709)
                     /locus_tag="VXC78_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0583920.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3775..4737
                     /locus_tag="VXC78_001907"
     CDS             3775..4737
                     /locus_tag="VXC78_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV0583921.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4943..5953)
                     /gene="ccpA"
                     /locus_tag="VXC78_001908"
     CDS             complement(4943..5953)
                     /gene="ccpA"
                     /locus_tag="VXC78_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV0583922.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6378..6977)
                     /locus_tag="VXC78_001909"
     CDS             complement(6378..6977)
                     /locus_tag="VXC78_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0583923.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSEKLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEMVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(6979..8076)
                     /locus_tag="VXC78_001910"
     CDS             complement(6979..8076)
                     /locus_tag="VXC78_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0583924.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILTVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(8076..8813)
                     /locus_tag="VXC78_001911"
     CDS             complement(8076..8813)
                     /locus_tag="VXC78_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0583925.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTAIFSFPVVLHTDKINNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMSLGNWIGAALLLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(8815..9699)
                     /locus_tag="VXC78_001912"
     CDS             complement(8815..9699)
                     /locus_tag="VXC78_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583926.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENIIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFILTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(9686..9880)
                     /locus_tag="VXC78_001913"
     CDS             complement(9686..9880)
                     /locus_tag="VXC78_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583927.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFICGALGFGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            complement(9877..10083)
                     /locus_tag="VXC78_001914"
     CDS             complement(9877..10083)
                     /locus_tag="VXC78_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583928.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         3286 a         2416 c         1899 g         3063 t
ORIGIN      
        1 gcaagcccta tctacgatac tgtttcaaga aacgagtcat cttttcttgg atttgggcta
       61 actcatcaac acgaggaagg taaacgatac ggaagtggtc tggttcctgc cagttaaagc
      121 ctcgaccatg aaccaagaga accttttcct gcttcaagaa atcaaggaca aactgctcat
      181 catcatcgat acggtacata ttgcggtcga tttttgggaa gatatagagc cccgccttgg
      241 gtttaacggc agacaaacct ggaatatctt gaatggcatt atagatgaaa tttctttgct
      301 cgtagattcg tccaccagga agaagcaatt catcgactga ttggtgaccc cccaaggaag
      361 tttgtacgac ttgttgggcc aaaacgttag agcaaaggcg catattggac agcatattga
      421 gcccttcgat atagccctta acatgagtct tagggccaga caagaccatc caacccacac
      481 ggaaacctgc tatgcggtgg gattttgaca gaccattcat gctgacacag aagacatctg
      541 gtgccaagct cgccacaggc gtatgcacat gtccgtccat taccatgcgg tcatagattt
      601 catccgcaaa gataatcaaa tcgttttgac gggcaatctc aataatctcc agcaagagtt
      661 ccttaggata aagggctcca gttgggttat ttggattgat aaggacaatt gccttggtat
      721 tggaagtgat ttttgacttg atatcgtcaa tatctgggta ccattccaca gcttcatcac
      781 agatatagtg aacggcattt cctccagcta ggctgacagc cgccgtccat agaggatagt
      841 ctggcattgg cactaagacc tcatccccat tgtccaaaag cccctgcatg gacatgacaa
      901 tcaactcact gacaccattt ccaaggtaaa tatcatcaat atctacgttt gggaatttct
      961 tcagctggca atactgcatg atggccttac gggctgagaa aatccctttg gagtcagaat
     1021 agccttcact atcacgcgca ttcataatca agtcatgaat gacctcgtct ggcgctgtaa
     1081 agccaaattc tgctggattt cctgtattca gacgtaaaat cttttctcca ttcgctcgca
     1141 tccgcatggc ttcttccaat acaggaccac ggatatcata agcaacatgc tctaacttac
     1201 tagacttgtt atattctttc atcttgtttc ctcaattcat caggatagta acattatacc
     1261 actagaaaga gaatgcgaca agtttactga aatgtgttac tagtttcgta tagaagaaaa
     1321 accttgctaa aggcgaggtt aagaacgtag agatagcagg tattttgcaa agacacatca
     1381 cataccaaaa gataaaccta gaaaaaagca agcctagaaa ggagtcataa agaagattaa
     1441 acatgaggaa aagcccccat atcatcaagt aatcccaacg cccacttcgt tttgcaacta
     1501 gaaataagat tagatggtag agtacatgaa aaactaaaaa tccaataaaa cttggataaa
     1561 gaagcggtac cagactctct aattgacaga tcatgatcac ttctaccaag actgaaacta
     1621 ggataattcc ataataaagg aaatttgatt tttgaaaaga gtttttcatc attctccctt
     1681 ccttcacttc tttcctgcta tcctttcttt tattttatca tatatttata tagagtttaa
     1741 gccctaatat tcttttgaaa aatacttttt ttgctttact tctatagtga aaaggtttac
     1801 aattatagta agaaaatttc aggaggtttc attatggcac aacgttacca aaatatcatg
     1861 gtcgcaatcg atggttctaa ggaagcggac ttggcttttg tcaagggagt tcattctgct
     1921 ctacgaaacg acgctaaact caccatcgca catgtcattg acacacgcgc tctccaaagc
     1981 gtatccacct ttgatgctga agtttacgaa gaactccaag tcgacgctga aagtctgatg
     2041 aaagagtacg aaaaacgtgc taaagatgct ggggtagcag atgttcatat cgtcattgaa
     2101 atgggaaatc caaagaccct gctagcacgt actattccag atgccgagga agtggacctc
     2161 atcctcgttg gcgcaactgg tctcaacgcc tttgaacgcc tcttggtcgg ctcttcatct
     2221 gaatacatac tccgccatgc taaggtcgat ttgctggttg tgagagaaca agaaaaaacc
     2281 ttataatcac aaagaaaagg agcccctagc tcctttttgt ttacgattta tttctctctt
     2341 tatggcgttc gtaagccttg agctggcgct gcagttcctt tttaatagca ggttctggag
     2401 catatttttc ttcccaatta tctggtttta agattttatg ggtcactgga tcaaaatgag
     2461 ccttgccatc tggaaaaatt ttccccatat tggcctgatg gacaatatca aaaatacgtt
     2521 ctgggtccac ccccatcaag acaaaactgc cgtaggtgaa gtaaagcgtg tcaatcaagg
     2581 catccacttg ccctatcaaa tcttgctgag caggtgtctt cttggctact ttacctgctg
     2641 ccttatcaag ggcctgatga agttgcgata cagcttgacc aaaatcttct tcagaaggac
     2701 tggctgatcg aacaaactcc accaattctt ctattttaaa accagcccta tgggttgcac
     2761 cctctaaatc ccaagctcga ggttcttctt gggttcgttc atccatcatg tggtggaagg
     2821 tcttgacctt attgaaatga tagtcacggc tgacaaaaac tttttctgaa gacaaaacac
     2881 caaaatgttc caaggccttg tggatcccat cttgttgatt gctagtggta atgtgcttgg
     2941 cagcttcctt gacactgcta ctaccatttc ccatagcgac cgacataccg acgccagcca
     3001 gcatttcaag gtcattatct gagtcaccaa aagccatgac ttggttgagg tcaaagccat
     3061 attctttccc aactcggcga atgccttcta atttagaatt tccctgattg atgacatccg
     3121 atgcaaaagg attgctacgt gtcaatttca agtcttcaaa atcagctgcc gccttctcag
     3181 attcttctgg tgtcatcagc atcaaaactt ggtaaatagg ttgattcatc aggtgaagca
     3241 ggtcctcttc cttttgggga acaaccttgc tgaccatgcg attaaaagac tgactcaccg
     3301 tccgagttaa aacagaggga acgaagcgac taattcgttg ggaaaaagaa cccagaccaa
     3361 aggacatgat tttagaaccc aacatggcat ccttggtccc taaggcaatc tccgtgccct
     3421 cttttttagc atagctaatt agatggcgca aatgtaactt ggaaataggg ctcgtgaaca
     3481 agactctgtc tttactaaag atatactggc cattataggt taccgcaaaa tccagatcca
     3541 aatcgtccat caattcctta acaaaaaaag gtcctcgccc tgtcgctacg ccaactagta
     3601 ccccttgttc tttgacaatc ttaatcgcat ccttagtgga tttcaaaaca ctcttgcgat
     3661 tgttgaccaa ggttccatcg atatcaaaaa aaacagcttt gacttccatc ctatcccaat
     3721 ctcccctttt gtgatacaat gattatacca catttcagaa agagtgagta aatcatgcct
     3781 aagaaaatcc ttgttttaca tacgggtgga actatttcca tgcaggccga tgcttctggc
     3841 gctgttgtga cgagttcaga taatcccatg aaccatgtgt ccaacccact tgaaggaatc
     3901 caagtccacg ccttggactt ttttaacctt ccaagtcccc atatcaaacc caaacatatg
     3961 ctggtcctct accagaaaat taaagaggaa gcagataact acgatggagt ggtgatcaca
     4021 cacggaaccg atactttaga ggaaacagcc tatttccttg ataccatgga agttccccat
     4081 atgcctatcg ttctaacagg agccatgcgt agctccaatg aactcggtag tgatggtgtt
     4141 tataattacc taagtgcttt acgagtggcc agcgatgaca gggctgctga caaaggagtt
     4201 ttggtcgtta tgaacgatga aatccacgct gccaagtatg tcaccaaaac acatacgact
     4261 aatgtcagca ccttccagac tccaacacat ggcccccttg gtctcatcat gaaacaggaa
     4321 atcctctact tcaaaacagc tgaacctcgt gttcgctttg accttgatca catacaaggt
     4381 ttagtcccta tcatctcggc ttatgctggt atgacagatg agctgattga tatgctggat
     4441 ttagaacact tggacggttt gattatccaa gccttcggag ctggtaatat tcccaaagaa
     4501 acggctcaaa aattagaaag ccttctgcaa aaaggaattc cagtcgctct ggtatcacga
     4561 tgctttaacg gtattgccga gcctgtttat gcctaccagg gtgggggcgt acagttgcaa
     4621 aaagcaggcg ttttctttgt taaagaactc aacgcccaaa aagctcgctt gaaactcctc
     4681 atcgccctca atgccggact aacaggacag gctttgaaag actatatgga aggctaatac
     4741 tcttcgaaaa tctctgcaaa ccacgtcacg tcgccttacc gtatgtatgg ttactgactt
     4801 cgtcagtttc atctacaacc tcaaaacagt gtgttgcgca gcctttaacc agccgcctag
     4861 tccgctctat ggtattcatt aagtcaacat ctcttgttta agagcacaaa atcaggaaat
     4921 cttctcgatt ccctgatttt ttctatttac gttttcgtgt tgagctacgt tctgtcaaac
     4981 catgaggtaa gagaacttca cgttcttcca actcttcctt atgcataatc ttggtcaaca
     5041 tacgcatact aatggcacca aggtcataaa gaggttgggc aatcgttgtc aagtttggac
     5101 gggtaaagcg tgagatttgt gaatcatcac tagtaataat ttcaaaatct tctggcacag
     5161 aaacaccctt atcagccaaa ccgttcaaga ctcctgctgc caactcatca cctgtcacaa
     5221 ctgctgcagt tgcatttgat gaaatcaaac gctctgctaa ggcgtaacca tcatcatagc
     5281 tatatttaga ttcaaatacc aaaccctcac tataagtgat tcctgctttt ttcaaggttt
     5341 ccttgtagcc aactaaacga accttaccat tgatgtcatc cactagcgga ccgctaacga
     5401 aagcaatacg ctcattttct ttagcaaggt aactcactgc atcaattgtt gcttgcttat
     5461 agtcaatatt gacacttggc aactggtgct caacatcgac agttcctgcg agaacaatcg
     5521 gagtacgtga acgcgaaaat tctgagcgaa ttttatctgt caagtgatac cccatataga
     5581 taatgccatc tacctgcttt gaaaagaggg tattgacaac agaaacttct ttctcgttat
     5641 cttcatcgct attagctagg acaatattgt acttgtacat ttctgcaata tcatcaatcc
     5701 ccttagccaa actcgaaaaa taaccattgg taatatttgg aatcacgaca ccgacagtgg
     5761 ttgtcttttt acttgcaaga ccacgcgcaa ctgcatttgg acgataatcc aaacgatcaa
     5821 ttacctctag cactttttta cgggtattct cttttacatt tttattgcca ttgaccacac
     5881 ggctgaccgt cgccatggaa acacctgctt cacgagcgac atcataaatg gttactgtat
     5941 catctgcatt cattcctttt cctgtccttt ctatctcaca cattctttta caagtagagg
     6001 tactgattga agctctatat ctacttacaa aagtgaagat gtgaaaattt cgttttcata
     6061 tttctactta ttccattcta tcactaattg taaacacttt caagtgtttt ttgaagattg
     6121 attgaaaaaa tttcatagaa aacctaggtt tagctccttg ctaccacctt agactaaaca
     6181 aaaaggagga aactaagccc tcctaaagtt atagtaaaat gaaataagaa caggataaat
     6241 cgatcaggac agtcaaatcg atttctaaca atgttttaga agtagaggtg tactattcta
     6301 gtttcaatct actataggta ttgttccatt cactaccgtc aattttagca catagtcttc
     6361 atgaaaatat tatatcatca taaccaacca gattcttttg cgatattagc tgcctctgtt
     6421 cgattaccag catccagttt tgaaagaata ttggtgacat agtttcgaat agttccgttt
     6481 gagaggtaaa gctgatctgc gatttcttgg ttggataagc cccgggcgat tccctttaag
     6541 acagcaatct cttgttctgt caacggattg ggacgggtca tcaccatttc catcaattca
     6601 ggcgaatact ccttgcgtcc ttcgaggacg gtgtgcaagg tttgcatgag gtctgcaatg
     6661 cttcgttcct ttaatacata agcatccact ccagccttga ccgcacgttc aaaataccca
     6721 gcacgcttga aggtcgtcac cacaaccacc tttgtttcaa gcttttctga tcgtatccac
     6781 tccaagactt caagacctgt cttaacaggc atttctacgt caaggatggc gatatctaca
     6841 gactcctttt ctaatagttg gattgcttct tgcccattct tggcttgaag gacagactcc
     6901 acatctggtt gaagcgtgag caattgacac atggcatctc gcaacatact ttgatcttct
     6961 gcgactaata ctttcatctt agtttctctc cttataaggt agtcgaactt gcacttccgt
     7021 tggatgtttc tgactgatta cacttacttc tcctgaaaat ggaaaaacac gatctcggac
     7081 tgtatggagc tcatctcctt ttagaaaagc aaagccgcag ccatcatcac ttactgttaa
     7141 aatgagttcc ttctctgtcc gttctaattt taagtaagct ttagacgctt tggcatgttt
     7201 gatgatattg gtcaccaact caagcaaaat catagaagcc attgactcca attcttgagt
     7261 aaggctagca gtatctagtt ggttatccgt ttccacctca attccagcaa tttctaacat
     7321 ctttttcaca gtctctagtt cggatgtcaa agttctagac ttaagatttt ccacgatagt
     7381 tcgaacttca ttcatggaat ccttgctgat ctggtgaatt tcttttaatt ccttttccac
     7441 ctgtggataa gcctccatct gaaataactg caaggctaga tcagttttaa cactaagcat
     7501 agcaaaggta tgccccagac tatcatgcaa atcttgaccg atacgattgc gttcattttc
     7561 agcaagcaat agatttatct gggcattttg cttagcctgt gcttctttca aatcctccac
     7621 aattcgaatc cgaaccaagc caaaagtcat taaatcgaca aaagcaagaa ttacaagtag
     7681 atagaataga aactcaactt cgattctctg aaaaatcaac agttgaccca caacaaggac
     7741 ttgagcaaga agaaaagtcc agacatgtaa agactttaaa ccacctacgc tgaaatgata
     7801 gcttaagaga ttggatagga aaaagaaaaa ccagatataa ttaacagcca caaaggcagt
     7861 attcccaact acataagtca gcaggatgcc ccaatatagc caagatagac gctggctctt
     7921 agttgttaaa acacccaaat acgccactac aaatagaata tcaatcaata aatgccaggc
     7981 agaaagccac ccagtcacta cagttaggat ggggaaaacc ataaaaatta aactgatcca
     8041 aaacatataa tgtatgcttt tcagtctttc aagcattaag cattctcctt atgaccttga
     8101 aggtaaatgg tcaaaccaaa caaaactact gaaaaaacaa gtaaataaac tgtggctgat
     8161 agattgatgc caccctcatt taagaaggtc ttgagcaact ccatcaactg ataggtcggg
     8221 agacacttac ctactacttg catccagtct ggaaataaag agataggcat ccagagtcca
     8281 cctaaaacag ccaaccctag ataaagaaga ttgcccacga cagacatcaa ctgactagtt
     8341 ggtaagagag tcaaggtcaa accaagcgct acgaaggcaa tacttcctac tatcagcaaa
     8401 agtgcagccc caatccaatt tccaagagac atgtccacac ctcttacaaa atgcccaact
     8461 gagaaaacca ccaagattga aaccaaataa tcaaccagca tacttgttat ctttgataga
     8521 taatattcta ccatatttac agggctatga cgcaatgttt tctgccagtt gttgatcttg
     8581 tcggtatgta aaacaactgg gaatgagaag atagctgttg acatcatgga aaatgcagtc
     8641 atggagataa gataatcacg cataaaattc gcgagttcac ctggtgtgtc ctgatagata
     8701 ccagaaaaaa ataaatagaa agccgtcggc atccctaccg acaatagata atagattaat
     8761 tgtcgtttgg tcaataaaaa ttctatctta ctaagtgcta tccatcgttt catcttagtt
     8821 atctcccttc tgcgtctctt caaagattgt attcaacaaa ctacgattat taacttcgat
     8881 ttcttgcatc ctacatcctg cttgggctaa tagttcccag aaagcatctg cttctcgagt
     8941 gactacttgt aaagaatctt gctttagggt ccagttttca accaaatttg actgctctac
     9001 gacttccttg taagctatag gaaggataaa gtgcttttct atttcctcgc tacgcatagc
     9061 tagaggcgtc gtatctcgaa tcaactctcc cttatttaag agcaaaatgc ggtctgcagt
     9121 gtgttccact tcctcaatat aatgggacga atagagaatg gtgactcctt gcgcttttaa
     9181 ctcctggaca atttcccaaa aacgttgacg agttgaggta tccatggacg cagtaggctc
     9241 atctaaaaaa acaatctttg gtcgcccaat taaggtcaag atgaaagaaa agagacgctt
     9301 ttgaccgcct gataattttt ctgccaactg ttctttttgt tgcttgacaa actgcaatag
     9361 ttgatcaatt tcctgattgc tcaaaggatt tggatagata cgttgaaaga aagcaatcaa
     9421 ctctttaact tttaatttct gaacgattat attttcttga gggaggtaag ccctagtata
     9481 gtctaactta gaactcgtca ctggtaaacc ttgaatagat acttgaccgc ttgtgaccag
     9541 tttatctcca agcaaacaat ctaagagtgt tgtctttccg gcaccatttg gaccaattaa
     9601 ggcaacacat tcaccatcgt tgatttcaaa ggagatgttc cgcaaaattt ccttgtcttt
     9661 tattttctta ctcaattttt caactttaac cacagtcatg agactctcct ttcaaccact
     9721 ccattcccat agggaaaacg acgaaaatca taaatccaaa ccccaaagca ccacaaatga
     9781 attggcgaag caaggcttga tcaaaccaat cagtaaacat ttccactaac cataccaaga
     9841 gtgacaggcc gataaagaaa tagatgatcc ctctcttcat tcctcaaact cctttttcac
     9901 atctctgact aatttcaaac cttctctaac aagccaagac atgattccaa agccagcaaa
     9961 gaccttccaa ggaaaatggt agaaatcctc atccaatccc gaaaacatga gataggtcat
    10021 aactcctgct actactaaac tcattgcaat aatcatttta tttctcatct cttcttcccc
    10081 catttcatac tacaattata gtcttttaaa atcagaggag gcagaagctt ctgtcactag
    10141 aaaatatgac aaatgtcata aaaattctgt tcaaaacaag caagatacac tatacaataa
    10201 aacacaatca gaaaaatcta aggcaacttc ctcaaaagag atatcaaacc caattcacac
    10261 cataatgtaa actaatactt atttaaaatc aaaaagagta gaaattttta tcagacaaac
    10321 acatatatag tgtattgaat ctataacagt aggccttaaa tactaaaata tttctataaa
    10381 ttaatttaac tttcctgata gagctgttca tatcttattt caattctcta tattatacgt
    10441 tgaacaaaac ccttctattg ctttcttaaa aatttataag agttataaaa tctgttaaat
    10501 ttcaatgtgt atacctaaac tacggtattt attgaaaaga ctggagacaa aaagtatacg
    10561 ctgccaaaat gaattactga aaatcaaaaa agagagaacc aaactgattc cctcttaatg
    10621 tatataatat ctagttttaa aaatacacac tcacatatct ctgt
//
LOCUS       DAVLCS010000060        10508 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLCS010000060 DAVLCS010000000
VERSION     DAVLCS010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10508
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.060"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            83..916
                     /locus_tag="VXC78_001915"
     CDS             83..916
                     /locus_tag="VXC78_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583929.1"
                     /translation="MIEVSHLSKSFGDKIALNDISFTVKEGQIFGFLGPSGSGKTTTI
                     NILTGQLLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSKFY
                     NISKLRVDNLLKRVGLYDSCKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSGLD
                     PTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKLVEQGAPSELIQR
                     YNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGKLN
                     A"
     gene            909..1622
                     /locus_tag="VXC78_001916"
     CDS             909..1622
                     /locus_tag="VXC78_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0583930.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(1944..2036)
                     /locus_tag="VXC78_001917"
                     /pseudo
     CDS             complement(1944..2036)
                     /locus_tag="VXC78_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            2357..3058
                     /gene="pyrF"
                     /locus_tag="VXC78_001918"
     CDS             2357..3058
                     /gene="pyrF"
                     /locus_tag="VXC78_001918"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV0583931.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            3092..3724
                     /locus_tag="VXC78_001919"
     CDS             3092..3724
                     /locus_tag="VXC78_001919"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV0583932.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKDDQENWQEG"
     gene            3904..4309
                     /locus_tag="VXC78_001920"
                     /pseudo
     CDS             3904..4309
                     /locus_tag="VXC78_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4405..5169
                     /locus_tag="VXC78_001921"
     CDS             4405..5169
                     /locus_tag="VXC78_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583933.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            5169..5921
                     /locus_tag="VXC78_001922"
     CDS             5169..5921
                     /locus_tag="VXC78_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583934.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            5931..6629
                     /locus_tag="VXC78_001923"
     CDS             5931..6629
                     /locus_tag="VXC78_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583935.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFLEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            6626..7273
                     /locus_tag="VXC78_001924"
     CDS             6626..7273
                     /locus_tag="VXC78_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583936.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(7353..8214)
                     /locus_tag="VXC78_001925"
                     /pseudo
     CDS             complement(7353..8214)
                     /locus_tag="VXC78_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(8226..8984)
                     /locus_tag="VXC78_001926"
     CDS             complement(8226..8984)
                     /locus_tag="VXC78_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0583937.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKNFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            complement(8985..9662)
                     /locus_tag="VXC78_001927"
     CDS             complement(8985..9662)
                     /locus_tag="VXC78_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0583938.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(9622..10290)
                     /locus_tag="VXC78_001928"
     CDS             complement(9622..10290)
                     /locus_tag="VXC78_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0583939.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LSQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGDSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
BASE COUNT         3162 a         1727 c         2156 g         3463 t
ORIGIN      
        1 ttttttttaa gacgtttatt tgataaagct aagtaaatag atgttaagta aaaatgtaga
       61 atataaagga ggggcaatga gtatgattga agttagccat ttatcaaaaa gttttggtga
      121 taaaatagct ttaaatgata taagtttcac tgttaaagaa ggtcagattt ttggattttt
      181 aggaccatct ggttctggaa agaccacaac gattaatatt ctgactgggc agctccttgc
      241 cgataaagga caatctatta ttttgggaca aaaatctcaa aatttaacaa gcggtgaatt
      301 aaagagaatt ggattggtta gcgatacaag tggattttat gagaaaatgt ctctgtataa
      361 caatcttctt ttttatagta aattttataa tattagtaaa ttacgtgttg ataatttgtt
      421 aaagcgagta ggattatatg atagttgcaa gatggtagca ggaaaattat ccactggaat
      481 gaggcaacga atgcttttag cacgagctct tatcaacaaa cccgctgtac tctttctgga
      541 tgaaccgacc tcaggtctag atcccacaac ttctcgaaca attcatgagt taattttaga
      601 attgaaaaca gcagggacaa cgatttttct aacgactcat gatatgaatg aagcaactct
      661 tttatgtgat tatgttgcct tattaaataa agggaaatta gttgagcaag gagctccttc
      721 tgaactcatt caaagatata ataaagataa aaagattaag gttacagatt ataatgggaa
      781 tcagataact tttgatttta catcactaga acaggtatct caggctgatc tggaaaatat
      841 tttttcaatt cattcatgtg agcctacttt agaagatatt tttatcacat taacaggagg
      901 aaagctaaat gcttaaacgg tttctggctt tggtatggtt gcgttgtcaa attatccttt
      961 ccaataagag tattttattg caagttttag tgccttttgc tttcacatat ttttataaat
     1021 atcttatgga aacacagggg aaggtcaacg atcaacaggc attagttctt ttgatgatgt
     1081 gtttaccttt ttctttggct ttggctgttg gaagtcctat aactattatc ttgtctgaag
     1141 aaaaagaaaa gtacaattta caaactcttc tgttgagtgg tgttaaagga tccgaataca
     1201 ttttatcaac gatgtttctt ccttttttgc taacttttgt gattatggga actactcctc
     1261 ttattttagg agttacaatt gtacatactt ttaattatat tacaatcgtt cttctaacct
     1321 ctttatccat cattttattc tatttattga taggtttaac cgcgaagagc caagtagtag
     1381 ctcaggttat cagtcttcct gctatgattt tagttgcttt cttaccgatg ctatctggtt
     1441 tggataagac agttgcgaag ataacagatt atagttttat gggactgttt actaagtttt
     1501 tcacaaaatg ggagggattt tcatggaatg aaactctaat tcctaatcta acactactta
     1561 tttggattgt tcttctatta actttaatta cgataactat taggaaaaag aaaatttctt
     1621 aattgagtta ttttaatgat tataaacaca agtgggaagg aaaaatgaac tgatcttttt
     1681 gacagcaatt ctacagaata gtcttattgc tatattttga tttgagtgta cgaaaaaaga
     1741 aaaataacaa tagtgctcat actaattgca gaagttttgg gtgataagat aactgataaa
     1801 ttgcaataaa aaatgcaaca tttttaaatc tcctctataa gtgcttcaaa acctgtcttg
     1861 taatccaagt atttttgggg acggtgatta ataagctagc aaagcaccat taaggatttt
     1921 ttcggtaatt gttgccaaat cggtttaaga aaatactcac gaagaagtcc attcgcattc
     1981 tcattacttc ccctttgcca agatgaatag gcatccgcaa aataaaacag aattcccatt
     2041 tgttcaatta aagggtaaca agcaaactct ttttctctgt cctaagtgaa agtctttaac
     2101 tattcttttg gaaagagtct tgtgaggtgt tcaatagcag tcaacacata cgtgaccatg
     2161 tttttacttg acaagtgcta gtagaaataa tagaatagta aaaaaccttt aaagcagtcc
     2221 agagaggcag ctaaggttag acggtgaaag ggtggagact acccattttt cgtggaacct
     2281 tgctgttggc aggttccttt tttcgtggct tctgttggcc agactctctc actagtaaag
     2341 gtaaaaggag aaacctatgc gagaacatcg tccaatcatt gctcttgatt ttcctagttt
     2401 tgaggcggtc aaggaatttt tagctctttt cccagcagaa gaaagccttt atctcaaggt
     2461 agggatggag ctttattacg cagcggggcc tgagattgtg tcctacttaa aaggtttggg
     2521 tcatagtgtc tttttggatc tcaaacttca tgacattcct aatacagtca agtcagcaat
     2581 gaagatccta tctcagcttg gtgtggatat gaccaatgtt catgcggctg gtggtgtaga
     2641 gatgatgaag gctgcgcgtg aaggtcttgg aagtcaagcc aaattgatcg ctgtaactca
     2701 gctcacatca acgtcagaag ctcagatgca ggagtttcaa aatatccaaa ccagtctgca
     2761 agagtctgtg attcactatg ccaagaagac agctgaagct ggcttggatg gtgttgtttg
     2821 ctcggctcag gaagtacaag tcatcaagca ggctaccaat ccagatttta tctgtctgac
     2881 accagggatt cgtccagctg gtgttgcagt tggagatcaa aaacgagtca tgacacctgc
     2941 tgatgcctat caaatcggca gtgactatat cgtagtggga cgtcccatta cccaagctga
     3001 ggatcctgtt gcagcttatc atgccatcaa ggatgaatgg acacaggact ggaattaaag
     3061 aactagatta gaaaaataaa aggagaatac catgacactt gctaaagata tcgctagcca
     3121 cctcttgaaa atccaagccg tttacctcaa accagaggaa cccttcactt gggcatctgg
     3181 tatcaagtca ccgatttaca ctgataatcg tgtgacacta gcctatccag aaactcgtac
     3241 cctaattgaa aatggttttg tggaagctat caaagaagcc tttcctgaag tagaagtgat
     3301 tgcaggaact gcaacagcag ggattccaca cggagccatt attgctgata agatggactt
     3361 gccttttgcc tacatccgta gcaaaccaaa agaccatgga gctggtaatc aaatcgaagg
     3421 tcgcgtagct caaggtcaaa aaatggtagt ggttgaagac cttatttcaa cgggtggttc
     3481 agttcttgaa gctgtagcag cagccaagcg agaaggagca gatgtgcttg gagttgtagc
     3541 gattttcagc taccaattgc caaaagcaga taagaacttt gcagatgctg gtgttaaact
     3601 tgtgacgctt tcaaactata gcgagcttat ccatctagcc caagaagaag gttacatcac
     3661 gccagagggc cttgatcttc taaaacgctt taaagacgac caagaaaatt ggcaagaagg
     3721 ttaggtcagt aagataaaga gagacgaggc taccgagcct cttttaccat tttatttaaa
     3781 atatgacaat attttaaata aaataattga caacgctttc ttttattgat ataatgaaaa
     3841 tgtaatatgt atcaaattga tcaatcaact atcttgttta tcacttctta agaggacgat
     3901 gtcatgaaaa gaagaaaaat atattccttt tttgcgtagt tacaattgca tctagtttgt
     3961 ttctccctac agttttagct agacagattg gaaattatga tttaacgttg ccgcgttggg
     4021 gttcggatac aactagtgag cttgagaaag aaaacgcctc tgctggaatt aataatagtg
     4081 acagcactgg tggcggtaaa aggttaaata cctctattcg tagcgcgcct atagtgggtc
     4141 agatattacc ccggtatatt cattggggtc tggctctagg attgtcatgt actataatgg
     4201 aggtggtgac aattatattg gttctggtac tagattagct atggcgccac aatttggaaa
     4261 tcatgtaaga attcatactt caggttcttg gagtccagat tcttattaac ttacttgtca
     4321 gagtaagcct taaagatggt tgattgtggg tgtagcatga aaaaagaatg ctacacccta
     4381 tttttattat aaggaggagt aaggatggaa tttttcattt gtaatcttgt acgagtcgtt
     4441 caatcacctc gattttatat gtctttattt ttgacccttc tttgcatgag tttaggaaat
     4501 ttccttgctt tcaatggtat ttataaaatt gaaggtttat cgattttttt tgccgcttct
     4561 tctattcgag gattttcacc gattagccta gtagctgcac ttatctgtac actgccctat
     4621 tctagtcaga taatagagga tgctgagagt cattttctaa cagcacaatt gtgccgaatt
     4681 tctaaaaaga ggtatctagc tattgtgggt agtactgcaa ttatttcttc ttttctagtc
     4741 ttttttctcc cctatttatt attattagga attaatcttt tagtgactcc ttatcaggaa
     4801 atttatattg gagattatag tggtgcctta aaagaattat ttgattctaa tcagttgctc
     4861 tatagtcttg tgacgactct ctggtatgga gtttggggcg ctgtgttctc tatttttgga
     4921 ctagctagtg ctttgctagt gaagaaaaaa ataggagcta ttttcatccc agttgcctat
     4981 atgatggttg gtggtatttt ttgggctatt ttagggctat cttacttaga acctgtgaca
     5041 acattagctt tgggatatca gaaagatatc agtctttcct tagttagtgg gcatcttgct
     5101 tttattttat ttgttagttg tttggttgtt tatggtacat tttttctaca ttcagaggac
     5161 tacgtataat gaaacaattt gttcaatttt acaaaaaaga ttttttatca gtattggttt
     5221 attttatatt actgctatcc tgtgttttat ctagtacagt atatttattg cgctgtcgcc
     5281 aatattcaat ccatccaaat gtattagaat ggatcttagt tttacttcaa gatatgacga
     5341 ctggagtata ttgctttccg ttcacatata tattgttctt tttttatttg atgaataact
     5401 attttaatag gttggagtgt cgcattcgtc tgaaatcaat taagcacttt accagtttta
     5461 gtttcaaatt agcagctctt agtacgggga tttggacggc gactttattt ttattgattt
     5521 ttctaattgc atttagtaat ggttttagct tctctttgga gataaaggag gttgattttt
     5581 taagagaatt ttatggtata agtattgcaa acaatgctag tttctttata ggattttttt
     5641 tctcttatat agcatactat ttctttttat ccttacttac tattagcagt ttttcttggt
     5701 ttaaaaaatc aaacatgagc ttagtatttc tgtttacttt tttatttgta gaatccttat
     5761 tctggattta tcagttggac aatgggataa ttggattatt gccaattttt cagtatatgg
     5821 taaattccaa tccgtatgca ttgatttatt ggcttacatt actatctatc ataattccat
     5881 tgactgtatt ttctgttcat agaaactgga ggagagtgta aaagttggaa atgggaaagt
     5941 taagtagtca catgtggagg ttgaatcaga taatctatac caagtacttt tggggttatg
     6001 ttcttttttg gatattgatt tgtttaggat tatggtattg gttagaagga aatgatagac
     6061 ttgttataga aattttaaaa gggcctaatc tgagtcaaaa ctctttttta gtcttatcta
     6121 tatggttgct tcattggttt attattcata cattttttct agcagttgta tatcgtagaa
     6181 gagcatccga tttctttctg gaagtgattc gattttcttc tattaagctc tggattaggt
     6241 atcagatttg gacctgtttt ctttatggac tcattttaat catggtaaaa gttctagtga
     6301 ttcaatttat gttacagtta ccaaactggg atataggagt tttgtttata gttgattctt
     6361 tgaatgcttg tgtgttagtc ttgttttgct ttatgttata cgcactagga gcgaatgtac
     6421 aaatgaactt tgcttgcgtt agtttctttt tactcatgat tgtgtttggt ggtctatttg
     6481 taggaaatcg aactaattat ctattttata ttttgaatcg agggaatgga gatataggac
     6541 gagatttatt tcttcagttg ctatttttag tctttctttt taaaagtatt ttctatttca
     6601 ctcgtcaaaa gaggaggttt atagaatgaa tgaaataatc atattaaaaa atattgagtt
     6661 gaaattaaaa aaaacatgtg tttttcaaaa ccttaatttt agttgtaaac agggggaaat
     6721 tataggaatt actggtgcga atggctcagg gaaaagtgta ttgtttaaat taatagctgg
     6781 tttatatagt ccgtcttatg gagaagtgtt aatcaatggg gaaaatattg ttcctgagag
     6841 aaaaattcca gctaatttgg gagctttgat tgaagaacct ggttttataa attattatag
     6901 tggctttaag aatttacaat atttggcaag catacgagga gtagttggta atcaggaaat
     6961 caatgataca ctgaaaatag ttggtctata tgagcaaaaa gaccagaaag ttaaaactta
     7021 ttcgctaggt atgaggaaaa agctagggat tgctcaagca attatggaga atccctctat
     7081 tcttttacta gatgaaccta tgaatgcctt ggataaatca agtgtagaaa atatgagaac
     7141 attgtttaga aagctctcta gtgaaaaagg gacaacaatt ttgattgcta gtcatagtga
     7201 agaggatatt cgtatcttat gtgataaagt atatgcaata gaagataaag tatgtacact
     7261 gtgttcagat tgaacatctt agatagactc aggatgttat aggtaaaatc ttaaaaaggg
     7321 attggagctt aaaatccagt cccttttaag agttaatggc caccttcaac aaccaggtca
     7381 tctgctttag cagcgtcacc gtaggttggg tgaagtgttt tttcataggc cttgtggaag
     7441 aagttttcct tgcctaattt ttcaatatct ttattgatga agtctagcaa ttcttggttg
     7501 cctttttgaa ctgctgccgc aatggtatcg ggatcaccga gggaagtaat tcctacttca
     7561 aatcctttat tttcaagcgc ccaagctaga acttccgtat tgtcagttga aaaggcatct
     7621 ccacgtccgt caagaagagc ttggtaagag tcactgtatt ggtcgtattt ttggagtttg
     7681 atttctggat gattcttttc aaaataagtc tcagcagtcg ttccttttgt gacaattaag
     7741 gttttacctt caagttgttt gacgtctgta atgagaccag tcttaggtga tacgacaccc
     7801 agagaaactt tcatatatgg aagggcaaaa tcaacttgtt tcttacgttc gtcagttact
     7861 gtaaagttag caagagtaat atctaccttg tttgaaatca agtattccgc acggttggca
     7921 gcatcgactg aaatgtattt aaccttgaca ccaaggtctt tagctagttg gttccctagt
     7981 tcaatatcgt agccttggta agaaccatca ttgtcaacgt agccaaacgg ttttttatct
     8041 ccaaacacgg cgattcgcag ttcaccgcct ttttttgatt tcatcgatag tgcgagcttt
     8101 ggcagttgtt tttccagagg atgaaccagc gtttccacct gagctacaag cagtgataaa
     8161 gataagggca aaggcaagtg ctaaaacagt taagagtggt ttgaatagtt tcataagaat
     8221 ctcctttata gatatgagcc aaattggcta aagtcaaaga cgtttaaaaa ttcctgggct
     8281 cgtttggttt gcggattggt aaagaaggct tgagctgttc cttcttcagc gattttccct
     8341 tggtcgagga agataatccg gtcagcaatg gcttgggcaa actgcatttc gtgggttact
     8401 aaaatcatgg tacggccttc ttgggccaaa tcattgataa gttccagcac ctcacgcacc
     8461 atttctggat ccagcgaagc agtcacctcg tcaaaaagga tgatttctgg atgcattagg
     8521 agggcacgga caattgcaac acgttgcttc tgtccaccag ataattgacg ggcaaagcta
     8581 tgttgtttat ccagcaaacc gacacgatct agtaattgca aagcttcttc cgttacttct
     8641 ttcttgtccc ttccttgagt tttgataggg cctaggatga ggttttgtaa gacatccaga
     8701 tggggaaaga gttcataact ttgaaagacc atgccaatct tttggcgaac taggtgaaaa
     8761 ttttttttat tttcaacgat agactgacca tccagaaaaa tatctccacc ttgaatactt
     8821 tctaagccgt tgaggcaacg aaggagggta cttttcccac aaccagatgg ccctaggatg
     8881 acaacaactt cccctttttt gatttctaga gaaagtcctt ggaggatggg attgtctccg
     8941 aaggattttt ttagttcctt gatttctaag atagtttcag acatttagtt tctccaatgt
     9001 ttttctaagt gagtggatag tttggaaata gggtagcaaa ctgcgaaata taagactaga
     9061 atggttccat aaatccaaaa tgaagcagtt gggatggtca ggcgattgct atcgatgatt
     9121 tgttgtccaa ctttggtcac ttccacaacc ccaatcaaaa caactaatga agtggtttta
     9181 atcatccgag tgacaagatt gatagcctgc ggtagcagtc ttctcaagac ttgtgggatg
     9241 atgatgtggt agtaaagttg aacattagtc aagccgagtg cctgtccact ttcaaactga
     9301 tgtttaggga gagaagtgat agctccacgt accaagtctc ccatttcagc tgttccccag
     9361 agggtaaaaa cgataatagc tgaagtctca cctgagatat tgatattaaa gtttcgagcc
     9421 aagccaaagt aaacgatgaa gagtagcacc agctggggca tgatacggat aaattccaga
     9481 tacaatcgtg ttaaaaatcg tatgattcta gaatgggagg tcatgatgat tcccatgact
     9541 gttccgaaca tcatggataa gaggacagac aggatggata tcccaatcgt aacgcccaat
     9601 ccctgtaaga ttctcaggag attatttcct tgaaagagta cttggattcc cgaatcctgc
     9661 atggcggagc ctcctttcta tccagctaaa gaccagtgag atgggtagca gcatgatcag
     9721 ataagcaact accaacatag ctagcgcaat gtctgtctca tagtagagac caatcaaatc
     9781 cttggcgacg tacatgaggt cggccaaagc cactgctgag aaaacagagg tttccttgat
     9841 aaggaaaatg acattggcac taaaggaggg gagtgccacc gctgttgctt gcggaagaac
     9901 cacatagtaa aagacctgta gaggtgtcag accaatagcg aggccaatct cctgctgggt
     9961 ttgactgatg gcttccagcc cacttcggaa agattctgcc atataggagt ctcctaaaaa
    10021 gacaagccca agcgttgcac agacttctga agataggaca atcccgattc ggggaagacc
    10081 gaagtagaga aagaagagtt gaatcaaaag gggcgtatta cgtgacaatt caatgtaggc
    10141 tgtcgctact tgcgacaaaa caaggattcg ataatgtcgg atgatactaa cgattaaacc
    10201 gagcagaaag gatcccaaaa ttccccaaac tgcaatatgc aaggtcagaa agaatgcctt
    10261 ttgatatagt ggtagatatt gttcaacaat ggatcaatcc aaaaatagaa cctcccatct
    10321 agaaataata cagttattgt agcacttaaa atcttctttg gataatatct attttttatt
    10381 gccgttataa ggatttttat catagacata aaatttctga aatttccaaa caaaatattt
    10441 taaaagtttt gaaaaagagt taagatattt ttgtaataca caaagtaaac gcttacttat
    10501 taaggagg
//
LOCUS       DAVLCS010000061        10426 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLCS010000061 DAVLCS010000000
VERSION     DAVLCS010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.061"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            1..389
                     /locus_tag="VXC78_001929"
                     /pseudo
     CDS             1..389
                     /locus_tag="VXC78_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            475..687
                     /locus_tag="VXC78_001930"
                     /pseudo
     CDS             475..687
                     /locus_tag="VXC78_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            587..1033
                     /locus_tag="VXC78_001931"
     CDS             587..1033
                     /locus_tag="VXC78_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0583940.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1171..2475)
                     /gene="eno"
                     /locus_tag="VXC78_001932"
     CDS             complement(1171..2475)
                     /gene="eno"
                     /locus_tag="VXC78_001932"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV0583941.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2639..3085
                     /locus_tag="VXC78_001933"
     CDS             2639..3085
                     /locus_tag="VXC78_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV0583942.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(3082..3885)
                     /locus_tag="VXC78_001934"
     CDS             complement(3082..3885)
                     /locus_tag="VXC78_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV0583943.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLCAFAQASIVSGID
                     TCLDLINFDKKVSDADLVVVGEGRLDSQNFAGKAPIGVAKRTPVGVPVIAICGSLAED
                     LPPLPFENIQAVFSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3894..4223)
                     /locus_tag="VXC78_001935"
     CDS             complement(3894..4223)
                     /locus_tag="VXC78_001935"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV0583944.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4168..4539)
                     /locus_tag="VXC78_001936"
     CDS             complement(4168..4539)
                     /locus_tag="VXC78_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV0583945.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4598..6031)
                     /gene="glgA"
                     /locus_tag="VXC78_001937"
     CDS             complement(4598..6031)
                     /gene="glgA"
                     /locus_tag="VXC78_001937"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV0583946.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYCWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6028..7167)
                     /gene="glgD"
                     /locus_tag="VXC78_001938"
     CDS             complement(6028..7167)
                     /gene="glgD"
                     /locus_tag="VXC78_001938"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV0583947.1"
                     /translation="MKIDKYSAILGNTVGFHDMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVELGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7157..8299)
                     /locus_tag="VXC78_001939"
     CDS             complement(7157..8299)
                     /locus_tag="VXC78_001939"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV0583948.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTIKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8289..10217)
                     /gene="glgB"
                     /locus_tag="VXC78_001940"
     CDS             complement(8289..10217)
                     /gene="glgB"
                     /locus_tag="VXC78_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV0583949.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3197 a         2288 c         1831 g         3110 t
ORIGIN      
        1 caccaagtaa aaggaacaaa accaagaaaa gttgatagag atagacttaa aaactatctt
       61 actgacaatc cagacgctta tttgactgaa atagcttctg aatttggctg tcatccaact
      121 accatccact atgcgctcaa agctatgggc tacactcgaa aaaaaagaac cacacctact
      181 atgaacaaga cccagaaaaa gtagccttat ttcttaagaa ttttaatagt ttaaagcacc
      241 tagcacaggt ctaacaaatg aatggtgagt taatcgctcc aatgacttac gaagagacga
      301 tgacgagcga cttttttgaa gcttggtttc agaaatttct cttaccaaca ttaaccgcac
      361 cattggttat tatattaaaa cgaagtaaga ataggacaaa tcgatcagga cagtaaaatc
      421 taattctaac aatgttttag aagtagaggt gtactattct agtttcaatc tactatatta
      481 atggacaatg caagattcca tagaatgggg aagctagaac tcttgtgtga agagtttggg
      541 cataaacttt tacctcttcc tccctactcg cctgagtaca atcttattga gaaaacatgg
      601 gctcatatca aaaagcacct caaaagggta ttaccaagtt gcaatacctt ttatgaggct
      661 cttttgtctt gttcttgttt caattgacta tataaattgt ctaagcgaaa caaccgataa
      721 gaattggcac aaaagcgacc gtatttttgt taccaataca ggaaaaccag ttcatagttc
      781 tatcttgagc aagtctctcc agcgagcaaa cgaacgcctt aaaaaaccaa ttcccaaaca
      841 tctgtcccct cacatcttca gacacaccac tattagcatc ttatcagaaa ataaaattcc
      901 tttaaaaaca atcacggaca gggttggtca ttccgactct gaagtcacta cttccatcta
      961 cacccacgtc acaaagaaca tgaaagatga agcaatcaat gtactggata aagttatgaa
     1021 aaagattttt taaaaagttt tgtccctttt ttgtcctcta aatacaaaaa tagcccttcg
     1081 gataaaatcc gaggggctag aaacgttgtt aaatcaacgg ccgaactttt gaatttcatg
     1141 gttcgggata aaatagttca ctgaactatt ttatttttta aggttgtaga atgatttcaa
     1201 tccacgatat tcagctactt caccaagttg gtcttcgata cgaagcaatt ggttgtattt
     1261 agcgatgcgg tctgtacgtg aaagtgaacc agtcttgatt tgtcctgcgt tagttgcaac
     1321 tgcaatatca gcgattgttg aatcttcagt ttcacctgaa cggtgtgata caacagcagt
     1381 gtaaccagct tctttagcca tttcgatagc ttcaaaagtt tcagtaagag taccgatttg
     1441 gttaactttg ataaggattg agttagcagc accttcttgg ataccacgtg caaggtagtc
     1501 agtgtttgtt acgaagaagt cgtcaccaac aagttgtact ttcttaccaa gacgttcagt
     1561 aagagctttc caaccatccc agtcgttttc atccatacca tcttcaatag tgatgattgg
     1621 gtatttgtta accaattctt caaggtagtc gatttgttct gcagatgtac gaacagcagc
     1681 accttcacct tcaaatttag tgtagtcgta aactttacgt tctttatcgt agaattctga
     1741 tgaagcacag tcaaatccga taaatacgtc tttacctggt acatatccag cagcttcaat
     1801 cgcagcaagg atagtttcaa caccatcttc agttccttcg aaacgaggag cgaatccacc
     1861 ttcgtcacct acggcagttt ccaaaccacg tgatttaagg attttcttaa gagcgtggaa
     1921 gatttcagca ccgtaacgaa gggcttcttt aaatgttggc gcaccaactg gcaagatcat
     1981 gaactcttgg aaagcgattg gagcgtcaga gtgagaacca ccgttgatga tgttcatcat
     2041 tggagttgga agaactttag tgttgaatcc accaaggtag ctgtaaagtg ggatttcaag
     2101 gtagtcagca gcagcacgag ctacagcgat agacacaccg aggattgcat tcgcacccaa
     2161 tttacctttg ttaggagtac cgtcaagtgc aatcatagca cggtcaatag cttgttgatc
     2221 acgtacatcg tagccaatga tagcttcagc aatgatgttg tttacgttgt caacagcttt
     2281 ttgtgtacca agaccaccgt aacgagattt gtcaccgtcg cgaagttcaa ctgcttcgtg
     2341 ttcaccagta gaagctcctg atggaaccat accacgtccg aaagcacctg attcagtgta
     2401 aacttctact tcaagtgttg ggttaccgcg tgagtctagg acttcgcgag cgtaaacatc
     2461 agtaataatt gacatttttt actctcctta tgagttaaat tttttacacc tctataatac
     2521 cttaaaaccc ctcctttttc aagaaaaaac gttatctttg tgcaactttt ccttaacttt
     2581 ataaagtaat cgctttcttt tgtctgtttt attctaactt ttatgatata ctgttttcat
     2641 gacagattta tcaaaacaat tacttgaaaa agctcatggt gggttaaaaa taaatccgga
     2701 tgagcaaaga cgctatcttg gtacttttga ggaaagagtt cttggatatg tagatattga
     2761 cacagcaaat agccctcagt tagaaaaagg ctttttattt attttagaaa accttcagga
     2821 aaaagcaaag ccactatttg tgaagatttc accaactatc gaatttgata agcaagtttt
     2881 ctacttaaaa gaagcaaaag aaactgatag tcaagccacc atagtatctg aagagcatat
     2941 tacttctcct tttggcctgg ttattcatag caatgcacca gttcaagtag aagaaaaaga
     3001 ccttcgactt gcttttccaa aactttggga agttaaaaag gaagaaccag ccaaaacatc
     3061 cttatggaag aaatggttta gctaaatctt gcacatattt aataagtgcc caatattggc
     3121 agccgtgcgc tccagataga gactggcatt tttcaaacta tcttctaaag gttcactttt
     3181 ctccaaaata gaaaagacag cttggatatt ttcaaatggt aggggaggta aatcttcagc
     3241 aagactaccg caaatagcaa taacaggaac tccaacaggg gttctttttg caacacctat
     3301 aggcgctttc ccagcaaagt tttgactatc aagtcttcct tctccaacaa caaccaagtc
     3361 agcatctgaa actttcttat caaagttgat taagtccaag caggtatcaa ttccagacac
     3421 gatacttgcc tgagcaaagg cacacaaacc agcagcaatc cccagtcctc catcattact
     3481 ggccgtgcca ccaacaccga tataaatatc tttaatccct ttagaaatga gatggagaat
     3541 caactctcca ataccacaag tttggatttg aagtggattt cgtttctcta gcggaatttt
     3601 tccaagacca accaagtcag ctacttcaaa tagtgccagt tccccttttt gaaaatagcg
     3661 catggcttct ttttgtccaa aagggtctgt cacttggatc catttttctt ttaggtcaag
     3721 agaatgtcgg atagcatcta cagtaccttc tcccccatca ccaacagggc agaggagaca
     3781 ttctacatct gctatcgatt gttggaagcc tctttttatt gcttcagcta cctgttgagc
     3841 tgtcaagctt tccttaaacg aatccggtgc aattacaatc ttcatatttt ccctcattct
     3901 aaacagtcaa tcaaaggaag aacttctaaa aaatccctct tgtcaacatg atgtggtatt
     3961 tcttttttga gcatttcttt ggaacaaaag gcgattccta actccgccga cttcaacatt
     4021 aatagattat taaccccatc accgattgcc accgttcttt ctttagaaag ttttagtttc
     4081 tttctccatt tttccagagt ttcttttttg acctggggac ttataatttg tccaactaat
     4141 tttcctgtta aaagaccttc tttgacttca agctggttgg cagtgaaata ggcaatacca
     4201 agggattttg ctaatctctc caactattgg tgtaaatcca ccagacacca gaccaactag
     4261 gatgccattc ttttggagaa tagagatgaa ctctgggaca tttagcgata gatgaattga
     4321 gttgaagacg ttatcaaaga ccaaaatagg aagaccttcc aacaaggaca ctctttttct
     4381 taaactgctt tcaaagacca actctcctcg cattgctcga cttgtaatct gcgaaatttc
     4441 cgcctcatga cctgcctctc tccctaaaag atcaatcact tcttctagga ttaaggttcc
     4501 atctacatcc aaaacacaca agccttttac ttgagacatc agttctcctc tctaaacagc
     4561 ctaaaaatcg tatgaagtca tcatacgatt ttatctatta attaactaaa ctatggtaca
     4621 agtcaaggta tgacttgcag gctgtatccc atgagaagtc actctccata gcttgttttt
     4681 gtaggtttct ccaaatgtct ggatggtttc tatacaagtc caatgctgtt tggaaagtcc
     4741 aatttaacca ataaggagat agattgtcaa agctaaagcc agtaccgctt ccttcgattg
     4801 gattgaaagc gcgaactgta tctcgcaagc ctccaacttc atggaccaat ggcaaggttc
     4861 cataacgcat agccatcatt tgagacaagc cacacggttc aaaacgactt ggcatgagga
     4921 agaggtcaca agcagcgtag atttcctgag caagtttgac atcaaaagtg atatttgctg
     4981 atagcttgtc tgggtaaatc tgagcaaacc atgagaaagc tccttcaaag gctggatcgc
     5041 cagttcccaa aagaacaatc tgaacatctt cttgcaagat atggtgaaga ctttcgacca
     5101 ccacatcaaa acctttttga cgtgtcaaac gagaaacaat tcccaccagt ggaacgtctg
     5161 ctctaacagg caagccaact ctttcttgca attttgcctt atttttggct ttcccagaca
     5221 aatcttcctg attgaaatga tagtctaaaa gagcatccgt ctgaggatta taaagatcag
     5281 catcaatccc attcacgata ccagatactt taccagactc cattttaaga atctgatcca
     5341 aattacatcc aaactgacta gtcataattt catgagcata gctaggtgaa acggttgaaa
     5401 cacggttcgc atagagaata cctgccttca tccagttcag acagttgttc catcgaaggg
     5461 tgccatcagc gtaacgttca aggccaactc caaacaaatc acccaacatt ccttctgaaa
     5521 attgtccttg gaattctaaa ttatgaatgg ttaaaactgt ttcaatgtcc tcataggctt
     5581 gaatccaaca gtatttttcc ttcaacaaga aaggaatcat agctgtatgg tagtcatgaa
     5641 catggagaag atcaggaata aagtcaatcc tttccatagc ctcaatggca gccagttgga
     5701 aaaaggcaaa gcgttctccg tcatcaaaat caccgtaaac atgaccacgg aagaaataat
     5761 attgattgtc aataaagtag aaggttacac catttaatac tgttttctta attccacaat
     5821 actgtctacg ccaaccaacg ctcacctcaa aatgaagcac atcttcaatc tgatttccaa
     5881 atttagcctc taccatatca tagtagggta aaatcactgc aacttcgtgc ccagctttta
     5941 ccagtgattt tggaagagcg ccaatgacgt ctcccaaacc acctgttttt gaaaagggtg
     6001 caccctctgc tgctacaaat aaaattttca tgaatgaata tcctctgtta ctttagcacc
     6061 tttcttaacc acaactggat gttctgcagt tcctcgaatc acaacaccaa gctcaacttc
     6121 aacccctttg tccaagatag catattcgac ctgagcccct tctccaataa caacacgagg
     6181 gaagagcagg ctatctttaa ccaagctatc cttatggaca tgaatattac gtgatagaac
     6241 agaattagct acttgacctt caataatact accagaggca aactgagaag tgcttacctt
     6301 agatgtatta gcataataag ttggctcttc gtttttgacc tttgtataaa tcttttggtt
     6361 tggtgagaaa agagaataga atttttgtga ttcaagcata tcgatatttg cttgataata
     6421 agatttaaca gagtgaatat tggctagata gcccgtgtac tcgtaggcaa aagctccctc
     6481 ttttacagcc aaatcccgta aaacatagcg caatttctct ggatgttctt ttttagcttc
     6541 ttcttccaag tgttcaatca accaaggtgt atcaacgaca aagatatctg tagacatatt
     6601 gaacgtttca gctgttgact tgctatcaaa gagtttatga gaaagaacat ggtctgtttc
     6661 atctacatcc aagattgcat ttacttctga aatatctttc ttagctagtt ttttataaac
     6721 tacagtgata ggctcttttg ttgtactatg taggtggaaa acttggttca aatcaatgtt
     6781 aataagaaca tcgcagttga gggcaaccgt ttggtttgag ccagaacgtt tcaaataagt
     6841 aagaagctgt tggtagtatt cttttccaac tgtactactt tctacacggg tattgtaaat
     6901 tcctagatag taatggctaa gaagggttga taagccccac tcgcgccctg aacgaatatg
     6961 gtcaaagact gagctgatat tatcctgctg gaaaatacca aagacactac gaacacctgc
     7021 attagcaagg cttgaaagtg ggaagtcaat caaacgatat ttcccaccaa atggcaaact
     7081 tgctactgga cggtggtccg tcaatgtcga catatcgtga aaaccaactg tatttcctaa
     7141 aatggcagaa tatttatcaa tcttcatctg ttgctacccc cactacttca ttatatccta
     7201 caacttgtac ttcatctgtt ccatcaattt cgacaccgtc agaaataatc gcaccttcac
     7261 caataatggc acgtttaatc ttagctcctt gaccaataat agctccactc atgataactg
     7321 aatcaaggac ttccgctcct tcgcgaactt gcgcgcctgt tgaaaggata gaatgtttaa
     7381 tagttccatc aacgaaacat ccgtctacaa ctaatgagtc ttccacatga gcatttgccc
     7441 cgaggaagtt tggtggtgaa atcaagtttc ttgagtaaat cttccattga cggttacgac
     7501 tatccaaggc attttctgga gaaatatact ccatgttcgc ttcccaaagt gactcaatag
     7561 taccaacatc tttccaataa ccactaaatt cgtaagcata aacactttca cctgactcaa
     7621 ggtaatttgg aatgacattt ttaccaaagt ctgacatgcc aaccttgctc ttttcagcag
     7681 cgactaacat attacgaagg cgttgccaat caaaaatgta gattcccata gaagcttttg
     7741 tagatttagg ttgagctggt ttttcttcaa attcaacaat acgattgtta gcatctgtgt
     7801 tcatgatacc aaaacggctc gcttctttaa gagggacgtc taaaactgct actgtcaagc
     7861 tggcattatt atccttatga gactggagca tatcatcata gtccattttg tagatgtggt
     7921 ccccagacaa aatcaagaca tactcaggat tgacactgtc gatatagtcg atattttggt
     7981 aaatagcgtg actagttccc tcaaaccaac gatttccttc acttgcagaa taaggttgaa
     8041 gaatagagac acctgaatta ataccgtcta gtccccagct tgaaccattc ccaatatggt
     8101 tgttgagagc aagtggttga tactgtgtaa ccaccccaac attatgaatc cctgagttgg
     8161 cacagtttga tagggcaaag tcaatgatac ggtagcgccc accaaattgc acagctggtt
     8221 ttgcgatgct ttgagtgagt ttaccgagac gagttccttg cccaccagca agaatcaaag
     8281 ctaacatttc atttttcatt ttctactcct ttttggtttt tatttgtgac ggttttagta
     8341 gatttcaagc gacgtttgat tttccataca cttgctccca tagccggtag ggtaaaggtt
     8401 aaggtctgct cataatcttt ccataggcct tcttgcgttt gaacagtttg attatgttct
     8461 ttccaaacgc ctccccactc ttccaactca gtattccata cttcttcgta aattcctgca
     8521 acgggtagtc cgattgtaaa atctttccgc tcaacaggta ccatgttaaa gatacagact
     8581 aacatttctc cctttttacc cttacgaata aaggaaagaa cactctggtc tcgattatcc
     8641 gcatcaatga tttcaatacc atcatagctg gtatcgattt cccacagaca gcgatgatct
     8701 ttgtaaaact ggtttagctg agaagtgaaa tacttcatct tagcattcat tgggtcttct
     8761 aggttagacc attccaactg ttcttcagat ttccattcta ggaattgacc gtattcgcta
     8821 cccatgaaga gcaatttctt accagggtga caaatttggt acgtatagag attgcgcaag
     8881 cctgcgaatt gattgtaacg atctccccac atcttatgca tcatactctt cttgccatga
     8941 accacttcat cgtgcgagaa tggcaagaga taattctcct tgaaaacata cataaagctg
     9001 aaagtcacca ggttaaagtc atatttacga taaatcggat cttcttcgta gaaacggagg
     9061 atatcattca tccagcccat gttccatttg tagtcaaatc ctagaccacc aatctctttc
     9121 attcccgtaa tcttggtcgc agacgaactt tcttctgcaa tcatcatcac atctggatat
     9181 tctaacttaa taacttcatt caagcgttga agaaaataat aaccttcata gttgagattt
     9241 ccgccatctt tattaggtgt ccatggagca ttatcatagt ccaaatagag catgttgcta
     9301 acagcatcca cacgaatacc atccaaatga tagacatcaa tccaatgctt aatgcaagaa
     9361 attaagaagg actggacttc attttttcca aggtcaaaat taagggcacc ccaaccatgg
     9421 ttatgagcct tattatggtc ttggtattca aaagtcggtg tcccatcata ataggctaag
     9481 gcatcatcgt tgatggtaaa gtgacctggt acccagtcca caataacccc aatattatgg
     9541 gtatgacact cctcgacaaa atcttgaaac tcctctggtc tgccataagc atgctctaaa
     9601 gcgaagtaac ccataagctg atacccccaa ctcaagccca aaggatggga catcaagggc
     9661 ataaactcaa tatgagtata gttcatttca acgagataag gaatgagttc atccttgagc
     9721 tgggcaaaac tataaggact gccatcagaa tttcttttcc atgatccagc gtgaacttca
     9781 taaatattga caggacgctc ttcaaagccc caacgttttc ttcgtgccag ccaaagtcca
     9841 tccttccatt tcttctcagg aagctctgtt aagattgccc ctgttcctgg acgagcctca
     9901 tacctgacag caaaagggtc aatcttcatc agttgatgac cattttgacg tgtgacatga
     9961 tatttgtaaa tatgcccttc ttgagccata ttggtaaaga cttcccagac cccaaaatca
    10021 tttcttacca ttggaatctg attttcaatc cagttggtaa aatcaccaac caagtgaaca
    10081 gcctgagcat taggtgccca aacacggaag gtatagccat gctctccatt tagttcttcc
    10141 ctatgtgctc ctagataatg ttggagataa aaattttcac ccgtcataaa ggtttttaat
    10201 gcttctctat tatccatata ctccccttct cctgtaagcg ttttctatgt ttttattata
    10261 ctaccttttt agagaagatt caagtaaatt actatacttc tttaattatt ttgaaaatct
    10321 acaacaagtt cacttactcg ttcaattgta aatcaatatt ttttcaaaaa attgcgaaaa
    10381 cgcctttctt tttctactat agtgaaatga aataaaacat gcgcaa
//
LOCUS       DAVLCS010000062         8988 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLCS010000062 DAVLCS010000000
VERSION     DAVLCS010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8988
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.062"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(1..855)
                     /locus_tag="VXC78_001941"
                     /pseudo
     CDS             complement(1..855)
                     /locus_tag="VXC78_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1111..1956
                     /locus_tag="VXC78_001942"
     CDS             1111..1956
                     /locus_tag="VXC78_001942"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV0583950.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(2103..3164)
                     /gene="dinB"
                     /locus_tag="VXC78_001943"
     CDS             complement(2103..3164)
                     /gene="dinB"
                     /locus_tag="VXC78_001943"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV0583951.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            3557..5881
                     /gene="pflB"
                     /locus_tag="VXC78_001944"
     CDS             3557..5881
                     /gene="pflB"
                     /locus_tag="VXC78_001944"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV0583952.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDKYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(5939..7201)
                     /locus_tag="VXC78_001945"
     CDS             complement(5939..7201)
                     /locus_tag="VXC78_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0583953.1"
                     /translation="MEHINHTTLLIGIKDKNITLNKAIQHDTHIEVFATLDYHPPKCK
                     HCKGKQIKYDFQKPSKIPFIEIGGFPSLIHLKKRRFQCKSCRKVTVAETTLVQKNCQI
                     SEMVRQKIAQLLLNREALTHIASKLAISTSTSTVYRKLKQFHFQEDYTTLPEILSWDE
                     FSYQKGKLAFIAQDFNTKKIMTILDNRRQTTIRNHFFKYSKEARKKVKVVTVDMSGSY
                     IPLIKKLFPNAKIVLDRFHIVQHMSRALNQTRINIMKQFDDKSLEYRALKYYWKFILK
                     DSRKLSLKPFYARTFRETLTPRECLKKIFTLVPELKDYYDLYQLLLFHLQEKNTDQFW
                     GLIQDTLPHLNRTFKTTLSTFICYKNYITNAIELPYSNAKLEATNKLIKDIKRNAFGF
                     RNFENFKKRIFITLNIKKERTKFVLSRA"
     gene            complement(7466..>8988)
                     /gene="rlrA"
                     /locus_tag="VXC78_001946"
     CDS             complement(7466..>8988)
                     /gene="rlrA"
                     /locus_tag="VXC78_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PI-1 pilus transcriptional regulator RlrA"
                     /protein_id="HEV0583954.1"
                     /translation="KYIEKRITDKITILNILLDIRSIELDELSTLTSLQSKSLLSILQ
                     ELQETFEEELTFNLDTQQVQLIEHHSHQTNYYFHQLYNQSTILKILRFFLLQGNQSFN
                     EFTQKEYISIATGYRVRQKCGLLLRSVGLDLVKNQVVGPEYRIRFLIALLQFHFGIEI
                     YDLNDGSMDWVTHMIVQSNSQLSHELLEITPDEYVHFSILVALTWKRREFPLEFPESK
                     EFEKLKNLFMYPILMEHCQTYLEPHANMTFTQEELDYIFLVYCSANSSFSKDKWNQEK
                     KTHTIQLILQHTRGKHLLSKFKNILGNDISNSLSFLTALTFLTRTFLFGLQNLVPYYN
                     YYEHYGIESDKPLYHISKAIVQEWMTEQKIEGVIDQHRLYLFSLYLTETIFSSLPAIP
                     IFIILNNQADVNLIKSIILRNFTDKVASVTGYNILISPPPSEEHLTEPLIIITTKEYL
                     PYVKKQYPKGKHHFLTIALDLHVSQQRLIYQTIVDIRKEAFDKRVAMIAKKAHYLL"
BASE COUNT         2655 a         1667 c         1826 g         2840 t
ORIGIN      
        1 gtaattgagc aggattatca aaggcatgaa tatttcgaat ctcggctaaa atgaccgccc
       61 ctaaacgatt ctcaatccca gtaaccgtcg tgatgaccga gttgaactca gccatcaagt
      121 cattgacaca ttttttcgcc ttgtcaatga gcctcttgta atgtttgatg ttttcgatga
      181 tttcgaattc acgagcagga gatgttgttc cgatagaacg aggtgcgact gagaggatat
      241 cctgaatttt agaagcggtc aatcgcttaa tttctatcag cttatcaaat cctgcctcaa
      301 gccttttctg aggattaggg tagcatgtca agagttggta ggtatattct gaatgctttc
      361 caacgatttt atccaactca ggaaagatga tatcaagaca acgagtgtat tgcactttcc
      421 aatcagactg ttttttcttg agacgatgaa tatgtctagc cagtattttt agttctactt
      481 gccgattatc gtgttgaaat tgttcacgat tggggtcaga aagaagttta agagcgatgc
      541 catgagcgtc tttcttatcc gttttagtct tgcgaagtaa taatgatttg gcaaatttct
      601 tgatgagcaa aggattgtag gtgtaaactt tatatccttg ttcatgcagg aagttcagta
      661 gattaaaggc ataatgtccg gtatcttcaa gagcgatgag atagtcttgg tcgagctgtc
      721 gaagagacag atctaaaagt tcaaaaccag ctttattatt tgaaaaagtg agtggtttaa
      781 gaacagtttt cctcgaacat tcaaggctgt aacatcgtgt ttatttttag cgacatcaat
      841 gcccacataa agcatgggag tacctccaga tatagtattt caagtctact tggttatcca
      901 cgaacttttt gccttgttac cttagacgag ataaaacgtc tatgcgttat caaactcatt
      961 accaattgaa acaaaaagct gtggttagac cctttcggaa atcgtcaagc gattggagga
     1021 aatgaactaa tccacagtgg cttattccaa gtataccact tgggctttgg cagtagctaa
     1081 ctgcgttaaa tataatataa ggagaaatat atgtatctta ttgaaatttt aaaatctatc
     1141 ttcttcggga ttgttgaagg aattacggaa tggttgccga tttccagtac aggtcacttg
     1201 attttagcag aggagtttat ccaataccaa aatcaaaatg aagcctttat gtccatgttt
     1261 aatgtcgtga ttcagcttgg tgctatttta gcagttatgg tgatttattt taacaagctc
     1321 aatcctttta aaccgactaa ggacaaacag gaagttcgta agacttggag actatggttg
     1381 aaggtcttga ttgccacttt gcctttactt ggtgtcttta aatttgatga ttggtttgat
     1441 acccacttcc ataacatggt ttcagttgct ctcatgttga ttatctacgg ggttgccttc
     1501 atctatttgg aaaagcgcaa taaagcgcgt gctatcgagc caagtgtaac agagttggac
     1561 aagcttcctt atacgaccgc tttctatatc ggactcttcc aagttcttgc tcttttacca
     1621 gggactagcc gttcaggtgc aacgattgtc ggtggtttgt taaatggaac cagtcgttca
     1681 gttgtgacag aatttacctt ctatcttggg attcccgtta tgtttggagc tagtgcctta
     1741 aagattttca aatttgtgaa agccggagaa ctcttgagct ttgggcaatt gtttttgctc
     1801 ttggtcgcga tgggagtagc ttttgcggtc agcatggtgg ctattcgctt cttgaccagc
     1861 tatgtgaaaa aacacgactt cacccttttt ggtaaatacc gtatcgtgct tggtagtgtt
     1921 ttgctacttt acagttttgt ccgtttattt gtataagaaa aaccttgaag gggcaactct
     1981 tcaagttttt atactcttag aaaatctctt caaaccgcgt cagctttatc tgcaacctca
     2041 aaacagtgtt ttgagcagcc tacggctagc ctcctagttt gctctttgat tttcattgag
     2101 ctttaaaatc cagtcatggt aatccccaat aggcggacac ctctttcttt ctcgcttaat
     2161 tcttcataga gttgcagggc tatttggctt atctgactag catcttgtgt tttttgagca
     2221 agactttttc gtttggtaag agttgaaaag tcctcgtagc ggattttcaa aatgacaatt
     2281 tttccagctt tttcttgttg atgtagattg agagcgactt tttctgatag aagagtcagc
     2341 tcttttttga tatcttcctc ggcacggaga atcttcccgt aggttttctc cttgccgatt
     2401 gatttacgga tgcgattgga tttgactgga gagttgtgaa tgccacgagc ctttcgatat
     2461 agatcatagc ctagtctacc aaaacggtct attagggtca cctcaggaac ttcaagtaaa
     2521 tcagcaccag taaaaacgcc catttgatga agacgttcta ctgtcttttt tcctactcca
     2581 tgaaatttgg aaatatccat ttgtttgaga aaatcctcag cctgttcagg tagaatcact
     2641 gtcaaaccat gaggtttttg ataatcactc gccattttag ctaagaactt gttgtaggaa
     2701 ataccggcag aagcagttag atggagttct tgccagatat ctttttgaat gaggcgagca
     2761 attttgaccg ctgacttgat accaagttta ttttctgtca catccaaata ggcttcgtca
     2821 atgctcatgg gttcaatcaa atctgtatag cgcttaaaaa tagctcgaat ctggagtccc
     2881 acagctttgt atttctcata atttcctgag ataaagacgg cttggggaca acgttcataa
     2941 gcttccttgg aactcatggc agaatggaca ccaaaagctc ttgcctcata actacaggta
     3001 gaaacgactc cccgtccacc tgtttgccga gggtcgcttc caataatgac aggttttcct
     3061 ctgagtttag gattatccct gatttccact gcagcaaaaa aggcatccat gtcaatatgg
     3121 atgatttttc ttgacaaatc atttaacaaa ggaaaaatca acatgcctag caccttttta
     3181 tactcttcga aaatctcttc aaaccccgtc agctctatct gcaacctcaa aacagtgttt
     3241 tgagctgact tcgtcagttc tatttacaac ctcaaagcag tgctttgagc agcctgcggc
     3301 tagcttccta gtttgctttt cgatttccat tgagtgttac tgcttatttt cttttattat
     3361 accctttttt ctgaaaaaaa gaaaaaagga ctttattttt tcaaaaatat aatacagttt
     3421 gaaataaaat atagactgtt ttagaaaaga aagtttaaaa atagggattt ttcacttgtt
     3481 gaaatcggtt actatatggt atacttgtct catgaatgta acagatgact gttactagaa
     3541 aaaagaggac attaatatgg ttgttaagac agttgttgaa gcacaagata tttttgacaa
     3601 agcttgggaa ggcttcaaag gcgtagattg gaaagaaaaa gcaagtgtat cacgctttgt
     3661 acaagctaac tacacacctt atgatggaga cgaaagcttc cttgcaggac caacagagcg
     3721 ttcacttcac atcaagaaaa ttgtagaaga aactaaagca cactacgaag aaactcgttt
     3781 cccaatggac actcgtccaa catctatcgc tgatatccct gctggattta tcgacaaaga
     3841 aaatgaagtt atctttggta tccaaaatga tgaactcttc aaattgaact tcatgccaaa
     3901 aggtggtatc cgtatggctg aaactacttt aaaagaaaat ggatacgaac cagacccagc
     3961 tgttcacgaa atcttcacta aatatgtaac aacagttaac gacggtattt tccgtgccta
     4021 cacttcaaat attcgtcgcg ctcgtcacgc acacactgta actggtcttc cagatgcata
     4081 ctcacgcgga cgtatcatcg gtgtttacgc acgtcttgct ctttacggtg cagactactt
     4141 gatgcaagaa aaagtaaatg actggaatgc aatcaaagaa atcgatgaag aaacaatccg
     4201 tcttcgtgaa gaagtaaacc ttcaatacca agcattgcaa caagttgttc gcctgggtga
     4261 cctttacggg gttgatgttc gcaaaccagc gatgaacgtg aaagaagcaa tccaatgggt
     4321 taacattgct ttcatggctg tctgccgtgt gattaacggt gctgctacat ctctaggtcg
     4381 tgtaccaatc gtattggaca tctttgcaga acgtgacctt gctcgtggta catttactga
     4441 atcagaaatc caagaattcg ttgatgattt cgttatgaaa cttcgtacag ttaaatttgc
     4501 tcgtacaaaa gcttatgacc aattgtactc aggtgaccca acctttatca caacttctat
     4561 ggctggtatg ggtaacgacg gtcgtcaccg tgttactaag atggactacc gtttcttgaa
     4621 cactcttgac aacatcggta actctccaga gccaaacttg acagttcttt ggactgacaa
     4681 attgccatac aacttccgtc gctactgtat gcacatgagc cacaaacact cttctatcca
     4741 atacgaaggt gtaacaacaa tggctaaaga cggatatggt gaaatgagct gtatctcatg
     4801 ctgtgtgtct ccacttgatc cagaaaatga agaacaacgc cacaacatcc agtacttcgg
     4861 tgctcgtgta aacgttctta aagcccttct tactggtttg aatggtggtt acgacgatgt
     4921 tcacaaagac tacaaagtat ttgacatcga tcctattcgt gacgaagttc ttgaattcga
     4981 atcagttaaa gcgaactttg aaaaatctct tgactggttg actgacactt acgtagatgc
     5041 cttgaacatc atccactaca tgactgataa gtacaactac gaagctgttc aaatggcctt
     5101 cttgccaact aaacaacgtg ccaacatggg attcggtatt tgtggatttg ctaacactgt
     5161 tgatacattg tcagcgatta aatacgctac agttaaacca atccgtgatg aagatggcta
     5221 catctacgat tacgaaacaa tcggtgacta cccacgctgg ggtgaagatg acccacgttc
     5281 aaacgaattg gcagaatggt tgatcgaagc ttacacaact cgtctacgta gccacaaact
     5341 atacaaagac gcagaagcta cagtatcact tttgacaatc acatctaacg ttgcttactc
     5401 taaacaaact ggtaactcac cagttcacaa aggtgtatac ctcaacgaag atggttctgt
     5461 gaacttgtct aaacttgaat tcttctcacc aggtgctaac ccatctaaca aagctaaagg
     5521 tggttggttg caaaacttga actcactttc tagccttgac tttagttatg cagctgacgg
     5581 tatctcattg actacacaag tatcacctcg cgctcttggt aagactcgtg atgaacaagt
     5641 tgataacttg gtaacaatcc ttgatggtta cttcgaaaac ggtggacaac acgttaactt
     5701 gaacgttatg gacttgaacg atgtttacga aaaaatcatg tcaggcgaag acgttatcgt
     5761 acgtatctct ggatactgtg taaacactaa atacctcact ccagaacaaa aaactgaatt
     5821 gacacaacgt gtcttccacg aagttctttc aatggatgac gccttggatg cattgagcta
     5881 atcaagttct tgaataataa aaagggctct ttgtcaactg tagtgggttg aagaaaagct
     5941 aagctcgaga aaggacaaat tttgtccttt cttttttgat gttcagagtg atgaaaatcc
     6001 gttttttgaa gttttcaaag ttccgaaaac caaaggcatt gcgcttgatg tctttgatga
     6061 gtttgttagt ggcctcaagt ttagcgttag aataaggcaa ttcaatggcg ttagtgatgt
     6121 agtttttata gcaaataaat gtgctcaaag tggttttaaa ggtgcggttg agatgaggta
     6181 acgtgtcttg aattaagccc caaaactggt cagtattctt ctcttgtaga tgaaatagga
     6241 gtagttgata caggtcatag taatctttaa gttcaggtac tagagtaaag attttcttca
     6301 gacactccct aggagttaag gtctctctga aagttctagc atagaaaggc ttaagagaga
     6361 gtttccgact atcttttagg ataaatttcc agtaatattt aagagctctg tattccagag
     6421 atttatcatc aaattgcttc atgatgttga ttctagtctg attaagagcc ctgctcatgt
     6481 gttggacaat gtggaaacga tcgagaacaa ttttagcatt gggaaataat ttcttaatga
     6541 gagggatata acttccagac atatcaacag tgacgacttt aacttttttt ctagcttctt
     6601 tcgagtactt gaagaaatga tttcggatgg ttgtttgacg tctgttatca agaatggtca
     6661 tgattttctt agtgttgaaa tcctgagcaa tgaaagccaa tttccccttc tggtaggaga
     6721 attcatccca ggagaggatt tcaggcaaag tggtgtaatc ctcttggaaa tgaaattgct
     6781 tgagcttacg atagacggta gaggtagagg tagagatggc taatttagaa gcgatatgtg
     6841 taagagcctc tctgttgagt aggagttggg caattttctg tctcaccatt tccgagattt
     6901 ggcaattttt ctgaacgaga gttgtttcag ctacagtgac tttccgacag gacttgcatt
     6961 gaaatcgtct ctttttcaaa tgaatgaggc tagggaaacc accaatctcg ataaaaggga
     7021 ttttagaagg cttttggaag tcgtatttga tttgttttcc tttacagtgt ttacatttag
     7081 gtgggtgata atcaagtgta gcgaagactt cgatatgggt atcgtgctga atggctttat
     7141 ttaaggtgat gtttttgtct tttattccga tgagtaatgt ggtatgattg atgtgttcca
     7201 taagatactt tctaatgagt tgtttaggcg cttttcatta taagtcttat gggacttttt
     7261 tgatactcaa aaagccctat aatctccaca gtgggattta cccactacag aaattataga
     7321 gccagaaaaa acacttttgt tcactagcag aaactagaga gcagaagtgt ttttctgttc
     7381 agatttaccc aaaactggga aatatgggga taagaataga gatggcttag gaagcccctt
     7441 tttgtgtgta gacagtacga tgaacttata acaaatagtg agccttttta gcaatcattg
     7501 cgacccgttt gtcaaaagcc tcttttcgga tatctacaat tgtctgatag atgagacgct
     7561 gttggctaac atgcaaatct aaggcaatcg tcaaaaagtg atgtttccct ttgggatact
     7621 gctttttaac gtaaggcagg tattctttcg ttgtaataat aatcaatggc tctgtcaaat
     7681 gctcctctga aggaggagga ctaattagaa tattgtatcc tgtaacagag gcaactttgt
     7741 cagtaaaatt ccgtaaaata atggacttta ttaagtttac atctgcttga ttatttaaaa
     7801 tgataaaaat cgggatagca ggtagtgagg aaaagatggt ttctgtcaag tagagtgaga
     7861 aaaggtacag ccgatgctgg tcgataactc cttcaatctt ctgctcagtc atccactctt
     7921 gaacaattgc tttcgaaata tgatacagtg gcttgtcgct ttcaatccca taatgttcgt
     7981 aataattata atagggaact agattttgta aaccaaacaa aaacgttctt gttaagaaag
     8041 tcagtgctgt taaaaaagaa agagaattcg aaatgtcatt tcctaagata ttcttgaact
     8101 tggatagtag atgctttcct cttgtatgct gaagaatcag ttgaatagta tgagtctttt
     8161 tttcttgatt ccatttgtcc ttggaaaacg aagaattagc agaacaataa accaaaaaga
     8221 tataatccag ttcttcctga gtaaaagtca tgttggcatg tggctctaag taagtttggc
     8281 aatgttccat caaaatcgga tacataaaga ggttttttaa tttttcaaac tctttggact
     8341 cagggaactc aagtggaaat tcccgacgtt tccaagtgag tgccactagt atgctaaaat
     8401 gaacatactc gtcaggtgtg atttctaaca gttcatgact gagttgagaa ttagactgca
     8461 caatcatatg tgtgacccaa tccatacttc catcattcaa atcataaatc tcaataccaa
     8521 aatgaaactg gaggagtgca attaaaaaac gaatgcgata ttcaggacca actacttgat
     8581 ttttcacaag gtccaaacct actgaacgta gtaacaagcc acacttttgt cgtacgcggt
     8641 agcctgttgc gatggaaata tactcttttt gtgtaaattc gttaaagctt tgattacctt
     8701 gtagtagaaa gaagcggagt atttttaaaa tagttgattg gttataaagc tgatggaagt
     8761 aataattcgt ttgatgagaa tggtgttcga ttaattgaac ttgttgcgta tctaaattaa
     8821 atgtcaactc ttcctcgaat gtttcttgta attcctgcaa aatgcttagg agacttttag
     8881 attgtaatga agttaaagta gacagttcat ctagttcaat agaccgaata tccaataata
     8941 tatttaaaat ggtaatttta tctgtaattc ttttttcaat gtatttgt
//
LOCUS       DAVLCS010000063         8926 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLCS010000063 DAVLCS010000000
VERSION     DAVLCS010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8926
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.063"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            122..277
                     /locus_tag="VXC78_001947"
                     /pseudo
     CDS             122..277
                     /locus_tag="VXC78_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            477..3752
                     /gene="rexB"
                     /locus_tag="VXC78_001948"
     CDS             477..3752
                     /gene="rexB"
                     /locus_tag="VXC78_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV0583955.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGAEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYIDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERKNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQPITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3749..7399
                     /gene="addA"
                     /locus_tag="VXC78_001949"
     CDS             3749..7399
                     /gene="addA"
                     /locus_tag="VXC78_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV0583956.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGCQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQITILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7614..8792
                     /locus_tag="VXC78_001950"
     CDS             7614..8792
                     /locus_tag="VXC78_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583957.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         2764 a         1865 c         1890 g         2407 t
ORIGIN      
        1 tagattgaaa taagatacga acagcttgat tagggaaatc aaattaattt ctagaaatat
       61 tttagcatcc acggtgtact attatagttt caatttacta tagttcaatc attctatcaa
      121 gaatattgaa tatataaagg cacgtaatat taaaacttct tctgatatcg aattagagtc
      181 cgatgttgat ggcgataaat cagacaatct acccgtcgac attaagatac tgggacaaca
      241 cattgaagtg tattccgtac ctaagaaaca atcataaaac tcaaagcctt gttaccgagg
      301 cttttttatt atgtgatttt cagtagccag acttattcta tctaatacaa gtaaagctaa
      361 gtatttaaga tttagcagat gatgaagaaa agaaaggatg gcctaaatat tttaacagat
      421 ttacgaggct aatcatggta taatataggg tgatgaaaaa ttccaacgag gctgagatga
      481 aattacttta tactgatatt cgaacttctt tgacagaaat tctaacaaga gaggcagaag
      541 agctagttgc agctggcaag cgggtcttct acattgcccc caactctctt tcttttgaaa
      601 aggaacgcgc cgtgctggaa tgcttgtccc agcaggcttc tttttcgatt accgtcacgc
      661 gctttgctca aatggctcgt tatctggtct tgaatgattt accagctaaa actactcttg
      721 atgatatcgg tcttgggttg gccttttaca aatgccttgc cgaactcgat cccaaggact
      781 tgcgtgttta tggcgctatt aagcaggatc ctcaattgat ccagcagtta attgagcttt
      841 accatgagat gaccaaatct cagatgaatt ttttggactt ggagaattta acagatgagg
      901 ataagagggc ggatttactc ttgatttttg agaaagtaac agcctatctt aatcaagggc
      961 agttagccca gggaagtcag ttgtcccatt tgattgaggc tattgagaat gacaaggtaa
     1021 gtagtgattt taatcaaatc gccttggtca ttgacggctt tactcgtttt tctgctgagg
     1081 aagagcgggt tgtggactta cttcacggca aaggtgctga gattgttatc ggggcttatg
     1141 ctagtaagaa agcctatacc agtcctttta gcgagggcaa tctctaccaa gccagcgtaa
     1201 aatttctcca tcatctggct tctaaatacc aaacgcccgc tcaggactgt tctcaaactc
     1261 atgagaagat ggatagtttt gacaaggcct ctcgtttgtt ggagtcttct tatgactttt
     1321 cagaactcgc tttggatgtc gatgagaaag accgtgaaaa tttacaaatc tggtcttgtt
     1381 tgacgcaaaa ggaggagttg gagctagtag cccgtagcat tcgtcagaaa ttacatgaga
     1441 actcagacct gagctacaag cattttcgta ttctcttggg ggatgtagct tcttaccagt
     1501 tatctctcaa aaccattttt gaccagtatc agattccttt ttatcttggt agaagcgaag
     1561 ccatggctca tcatcccttg actcagtttg tcgagtctat tttagcttta aaacgttacc
     1621 gttttcgtca ggaggatttg attaatcttc ttagaactga cttgtatatt gacctcagtc
     1681 agtctgatat tgatgctttt gaacaatata tccgctatct tggtattaat ggcttgccag
     1741 cctttcagca aaccttcacc aaatcccacc atggaaaatt taatcttgag cgtttgaatg
     1801 tcctccgcct gagaatttta gcacctcttg aaaccctctt tgccagccga aaacaaaagg
     1861 ctgaaaacct cctacaaaaa tggagtgtct ttctaaaaga aggagctgtg accaagcagt
     1921 tacaagattt gacaaccact ttggaagctg tagaacagga aagacaagcc gaagtttgga
     1981 aggctttttg ccatgtttta gaacaatttg cgactgtttt tgctggttca caggttagtc
     2041 tggaagactt cctagccttg ctccattctg gaatgagttt gtcccaatac cgtaccattc
     2101 cagcaacagt ggacactgtt ctggtgcaga gttacgattt gattgcacca ttgactgctg
     2161 actttgtcta tgctattgga ctaactcagg acaatttacc aaaaatttct caaaacacca
     2221 gtcttctgac agatgaagaa aggaaaaacc taaaccaaac gaccgaagaa ggcgttcaat
     2281 tactgattgc cagcagtgaa aatctcaaga aaaatcgcta cactatgctt tccttggtca
     2341 attctgctcg taagcagttg ttcttgtcgg ctccaagcct ttttaacgaa agtgaaagta
     2401 aggaatctgc ctatcttcaa gagttgatcc attttggatt taggcggaga gagaagagaa
     2461 tgaatcacaa aggactgtct aaggaggata tggggtccta tcacagtctt ttgtctagtc
     2521 tggttgccta tcaccagcag ggtgagatga gcgatactga gcaagatttg acttttgtca
     2581 aggttctgtc gcgtgtcata ggtaaaaaac tagatctgca aggtctggaa aatccagcta
     2641 tcccaaccag tccaagcagc aagaccttag ccaaggacac cttgcaagct ctctatcctg
     2701 ccaaacagga gttttacctg tctacgtcgg gtttgacaga gttttatcgc aatgaataca
     2761 gttatttcct acgctacgtt ttaggcttgc aggaggaatt acgtttgcgt cctgatgccc
     2821 gtagtcacgg gaatttcttg catcgtatct ttgaacgcgc cttacagttg cctaatgaag
     2881 attcctttga ccaacgtcta gaacaagcta ttcaagaaac cagtcaagaa cgcgaatttg
     2941 aagctattta tcaagaaagt ttggaagccc agtttaccaa ggaagttttg cttgatgttg
     3001 cacggacgac tggacatatt ctccgacaca atccagccat cgaaaccatc aaagaagaag
     3061 caaattttgg tggaaaagac caagccttta ttcaattaga caatggacgc agtgtctttg
     3121 tacgaggcaa ggtggaccgg attgaccgtt tgaaagctaa tggagcgata ggagtagtag
     3181 actacaaatc cagtctgact cagttccagt ttcctcattt ctttaatggg ctcaattctc
     3241 agttaccaac ctatcttgct gccctaaaaa gagaagggga gcagaacttt ttcggcgcca
     3301 tgtacttgga aatggctgaa cctgtccaat ctctgatggc ggtaaaaagt ctggcaggag
     3361 cagtggtaga agccagcaaa tctatgaaat accaagggct cttcttggaa aaagaaagca
     3421 gttatttagg cgaattttat aacaaaaaca aggctaatca actgacagat gaggaatttc
     3481 agctcctact ggactacaat gcctatcttt acaagaaagc tgctgagaag attttagcag
     3541 gccggttcgc catcaatcct tatactgaaa atggcagaag cattgcccca tacgtccagc
     3601 aacatcagcc tattacaggc tttgaagcca attaccatct gggccaagcc cgtttcctag
     3661 aaaagttgga cctagctgat ggcaagcgtc tggtcggaga aaaactcaag caagcttggt
     3721 ttgaaaaaat aagagaggag ttaaatcgat gaagcttatt ccctttttaa gtgaggagga
     3781 gattcaaaaa ctgcaagaag cagaagcaaa ttcgagcaag gaacagaaga aaactgccga
     3841 acaaatcgaa gctatctaca cttctggtca gaatatcctg gtctcagcat cggctggttc
     3901 tggaaagacc tttgtcatgg tagagcgcat tctggaccaa ttggcgcgtg gtgtcgaaat
     3961 ttctcaactc tttatctcaa cctttaccgt caaggctgca actgaactta aagaacgttt
     4021 agagaaaaaa atcagcaaga aaatccaaga aacagatgat gtcgatctca aacaacactt
     4081 gggttgccag ttggcagacc tacccaacgc tgccatcgga accatggact ctttcacaca
     4141 aaaattcctt ggcaaacatg gttatctgct tgatattgca cctaatttcc gtattttaca
     4201 aaaccaaagc gagcaacttc ttctcgaaaa cgaagtcttt catgaggtct ttgaagcgca
     4261 ttaccaaggt aaacagaaag agagctttag tcatttgctg aaaaactttg ctgggcgtgg
     4321 caaggacgaa cggggtctgc gccagcaagt ctataaaatc tatgacttcc tccaatccac
     4381 cagtaatcct caaaagtggc tgagtgaatc tttcctcaaa ggctttgaga aagctgattt
     4441 taccagtgaa aaagaaaaac tgactgagca aatcaaacaa gccctctggg atttggaaag
     4501 ctttttccgt taccatctgg ataacgatgc caaggagttt gcaaaggctg cctatttaga
     4561 aaatgttcag ttaattctgg atgaaattgg ctccctaaat caggagttcg atagtcaggc
     4621 ttatcaggca gtgcttgcgc gtgttgtcgc catctctaag gagaaaaacg gtcgagctct
     4681 gactaatgcc agccgtaagg ctgatttgaa gcccctggct gatgcctaca acgaagagag
     4741 aaagacccag tttactaaac taggacaatt atcagaccag ataaccattc tcgactatca
     4801 agaacgttat catggagaca cttggaaact agctaaaacc ttccaatctt tcatgagcga
     4861 ttttgtagag gcttatcgtc agagaaaacg acaggaaaat gcctttgaat tcgctgatat
     4921 cagccattac accattgaga ttttagaaaa tttcccacaa gttcgtgagt cttatcagga
     4981 gcgcttccat gaagtcatgg tcgatgagta tcaggatacc aaccatattc aagaacggat
     5041 gctggaattg ttgtctaatg gccacaatcg ctttatggtg ggagatatca agcaatccat
     5101 ctatcgtttc cgtcaggcag acccgcagat tttcaatgag aaattccaac gctatgcgca
     5161 aaatcctcaa gaaggcaagc tcattctcct caaggaaaat ttccgtagta gttcagaagt
     5221 gctgtcagca accaatgatg tctttgaacg tctcatggac caagaggtcg gcgaaatcaa
     5281 ctatgataac atgcaccagc ttgtttttgc caataccaaa ctgactccca atccagacaa
     5341 caaggcagaa tttctcctct acgacaagga cgatacaggt gaggaagaag agagtcaaac
     5401 agaaacgaaa ctaacaggcg aaatgcgctt agttatcaag gagattctga aacttcatca
     5461 agaaaaaggt gttgccttta aggaaattgc ccttctgacc tccagccgca gtcgtaatga
     5521 ccagattctc ctcgccctgt ctgagtacgg aattcctgtc aaaactgacg gagagcaaaa
     5581 caattatctc caatccctag aagtgcaagt catgctagac actcttcgtg tcattcacaa
     5641 tcccctgcaa gactacgctt tggttgccct tatgaagtct ccaatgtttg gttttgatga
     5701 ggatgagcta gcacgtttgt cccttcagaa agcagaggat aaagtccacg aaaatctcta
     5761 tgagaaactg gtcaatgcac aaaaaatggc aagtagtcaa aaaggtttga ttcacacagc
     5821 tctagctgaa aaactaaagc aattcatgga tatcctagct tcttggcgct tgtatgccaa
     5881 aacccactct ctctatgact tgatttggaa gatttacaac gaccgttttt attatgacta
     5941 tgttggggct ttgccgaatg gtcctgctag gcaggccaat ctctatgccc tagcactgcg
     6001 tgctgatcaa tttgaaaaga gcaatttcaa aggtttgtcg cgttttattc gtatgattga
     6061 ccaagtctta gaagcccagc acgatttggc aagcgtggcc gtcgcaccgc caaaagatgc
     6121 agtagagctc atgaccatcc acaagagtaa agggctggag tttccttacg tctttatcct
     6181 caatatggat caagatttca acaagcaaga ctctatgtca gaagtcattc tcagtcgtca
     6241 gaatggtctt ggtgtcaaat atattgccaa gatggagaca ggggcagtag aagaccacta
     6301 tcctaaaacc atcaaactct ccattcctag tctgacctat aggcagaacg aagaggaatt
     6361 acagctagca agctattctg agcagatgcg tttgctgtat gttgctatga cgcgggctga
     6421 gaaaaagctc tatcttgtcg gcaagggttc tcgtgaaaag ctggaagtca agcaataccc
     6481 agcagccaaa aatgggaaac taaatagcaa tactagactg caagcacgga atttccaaga
     6541 ttggctttgg gctatcagta aagtgtttac taaggacaag ctcaacttta gttatcgttt
     6601 tattggcgaa gatcagttga ccagagaagc tatcggagag ttggaaacca agagtcctct
     6661 ccaagatagc tcccaagcag acaatcgtca gtcagatacc atcaaagaag ctctggaaat
     6721 gctgaaggag gtggaagttt ataatactct tcaccgcgca gctattgaac ttcctagtgt
     6781 tcaaacccca agtcaaatca agaaattcta cgaaccagtt atggatatgg aaggtgtcga
     6841 gattgctggt caaggtcagt cagtaggcaa gaaaatcagc ttcgatttgc cagatttttc
     6901 aaccaaagaa aaggtaactg gagctgagat tggtagtgct actcacgaac tcatgcagag
     6961 aattgacctc agccagcaac taacccttgc tagcctaaca gaaacactca aacaagttca
     7021 aactagccaa gctgtcagag acaagatcaa tcttgataaa attcttgctt tctttgacac
     7081 agtactcggt caggaaattc ttgctaatac cgaccatctc tatcgcgagc aacctttctc
     7141 catgctcaaa cgagaccaaa agagtcagga agactttgtt gtccgtggta tccttgatgg
     7201 ctatctgctt tacgaaaaca aaattgttct gttcgactac aagacagacc gctatgatga
     7261 accaagtcaa ctcgtagacc gctatcgtgg tcagttagct ctatacgaag aggctttatc
     7321 acgagcctat tcgattgaaa atattgaaaa atacttgatt ttactcggta aagacgaggt
     7381 tcaagttgta aaagtataac ttatactctt tgaaaatctc ttcaaaccac gtcagcttcg
     7441 ccttgctgta tatatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt
     7501 ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgttttgag ctgattgcgg
     7561 ctagctttct agtttgctct ttgattttta ttgagtatta gaaaggagac ctcatgacac
     7621 ttccagttag aaaatccctg cacgatgcag ttttacaggc ttcgaaagcg gatacttggg
     7681 aacaagctac caaggaatgg aatgaagttt ccttgatttt taacggtatc ggccgtagca
     7741 attgtgtctg tggaaatgcc atcaaatacg cttatgaact ctttaacggt gtcacaggcc
     7801 aacgcctctt tccaattggt agcgactgtg ttcgtcattt tcatcgattg tcccttgacc
     7861 agcaattgga agaggaagaa aaactgctca gaaaggttga aaatctaacc agaaaagctc
     7921 agaaaaagga aaaaatcaag gtcaataaaa gtgactttga cgagcgactt ctaaaatggc
     7981 tctgggaaaa aggtgttttc aaacccaatc gtggcaatca atttgcgcct gagagagact
     8041 accagctttt cctagaagtc tttcagggag gaagttggac caaggcggaa ccaaagaaaa
     8101 aggctcggat ggaagaagtc cttgaaaagt gtatcaaacc ctttttactt gggaaatcgg
     8161 atgaccaact ctaccttgtc aagctaggca aggagaaaat tgactacgaa caagaactcc
     8221 gtatccaggc agagaaagaa cgcaagaaga gggataaaat cgccaagcaa tatgcagaca
     8281 atctggttct agccatggga cccgcagagc gtgcttatca agattacttt ggctttacag
     8341 agaccctgac tcaagaagaa cgcaagtggg aaaaaattct ttttggtaaa aatagagcag
     8401 aacgggctat caaggccaaa caataccaaa aagagctgga aaaagaccaa cgaattgcca
     8461 gtcaggatcc aattgaaaga aaacagaagc agacttggct cctcaattcc tattttcgtg
     8521 agcttcctga agaaaaagct cgattttcta ggctcttatt agaatatcga aaaagtggtg
     8581 aagtaccctt ttcaactgaa tacctgtccg atcatctcat cgactttttc tataaaatga
     8641 aagcctttga atttgaaatc gcaccagaac aagtccgaga ttttctaaaa aaaagcctgc
     8701 aggaagacca tcgctcatca gcacaaggaa gctggataga aggaattctc ctcaactgcc
     8761 tcaaaccatt tttagaacga ttagtgatat gagtaacacc taccgtgtaa atttcatggt
     8821 aggtgttatt gtacccccaa ataatataaa acaaagtatg aaagcgcatc tcaattttaa
     8881 gacttttttg taaattaaga gtataattaa ggtatactgc cttttc
//
LOCUS       DAVLCS010000064         8494 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLCS010000064 DAVLCS010000000
VERSION     DAVLCS010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.064"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            64..1743
                     /locus_tag="VXC78_001951"
     CDS             64..1743
                     /locus_tag="VXC78_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0583958.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEERQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            2011..2577
                     /locus_tag="VXC78_001952"
     CDS             2011..2577
                     /locus_tag="VXC78_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583959.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            2899..3087
                     /locus_tag="VXC78_001953"
     CDS             2899..3087
                     /locus_tag="VXC78_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0583960.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            3149..3907
                     /locus_tag="VXC78_001954"
     CDS             3149..3907
                     /locus_tag="VXC78_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0583961.1"
                     /translation="MVVYIRQSKLLSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIDVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            3965..4819
                     /locus_tag="VXC78_001955"
     CDS             3965..4819
                     /locus_tag="VXC78_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0583962.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKDYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            4931..5815
                     /locus_tag="VXC78_001956"
     CDS             4931..5815
                     /locus_tag="VXC78_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0583963.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            5978..7717
                     /locus_tag="VXC78_001957"
     CDS             5978..7717
                     /locus_tag="VXC78_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV0583964.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIWKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            7992..8447
                     /locus_tag="VXC78_001958"
     CDS             7992..8447
                     /locus_tag="VXC78_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583965.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSENLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
BASE COUNT         2966 a         1193 c         1807 g         2528 t
ORIGIN      
        1 tagtccaaac ttaaattaaa aaaattatat atgatataga aaaattatat tgaggttaat
       61 actatgtcaa aagaaaaaat aaaagtatac ctctatacac gagtatctac gtcaatacag
      121 atagaggggt attcgttaga ggcacaaaaa tcacgaatga aagcttttgc tatttacaac
      181 gattatgaaa ttgttggaga gtatgaagat gccgggaagt ctggcaagtc tattgaaggt
      241 agaatacagt tcaatcgaat gatggaagat ataaaatctg gaaaagatgg agtatctttt
      301 gttcttgtgt ttaagttatc aagatttgca agaaatgccg ctgatgttct ttctacactt
      361 cagataatgc aggattatgg agttaatctt atctgcgttg aagatggcat tgattcatct
      421 aaagatgctg ggaaactaat gatttctgtt ttatcagctg tggctgaaat agaaagagaa
      481 aacatccgta ttcaaacaat ggaaggttgc attcaaaaag caagggaagg aaaatggaat
      541 ggtggctttg ctccgtatgg atataaactt gaagacggca agctgtttat aaatgaggaa
      601 gaggcagttg caataagaac gattttcgac cagtatgtaa atactacgat aggagccaat
      661 gggatatcta aatacttaga gaatcatgga attagaaaaa tcccaagaca gaatggtaag
      721 aatcctttgt ttgatgcagg tcttataaga aagatattaa agaatcctgt atataatggg
      781 aaaatagcat ttggaagaag aactttagaa aaagttcatg gtacaagaaa tgaatataag
      841 caggttgaac aagatgaata tctaatatct gaagggatac atgaagctat agtttccgat
      901 gaagtttggc aagctgctca ggttaagcta aaatctcaag caaagaaata tgagcatgtg
      961 aataaaggaa aagatacacg cacacacttg ctttctggaa ttgtaaaatg cccgatatgt
     1021 ggagtgggaa tgtttgggaa caagtgtatc aagaaaaaga aagatggcac aaagtataaa
     1081 gatttttatt actatggttg taaacatagg cagatgataa gaggtcataa gtgtacattc
     1141 agtaagcaaa ttagagaaga attgttagat gatgctgttg cagaggtgat tgtcaagata
     1201 gtaagtaatc cgaaatttgc ttctatgatg caagaaaaaa tcaacatgaa ggtggatacc
     1261 tctgaaatag aaaaagaaat agataattac caaaaggaat tgagaaagag tcattctaca
     1321 aagtttaagc taattgagga aatagataat ttagatgttg aagataagca ttataagaga
     1381 aggaaacagg atttagatga tagactatat cgtatgtatg acaaaataga tgaattagaa
     1441 tcatcactaa ttgatgcgaa agcaaagaaa cagactattg aagctgaaaa gcttacagga
     1501 gataacatat ataaggttct aatctatttt gataagctct ataaagtcat gaatgatgta
     1561 gagcgtaggc agttaatttc agctttgatt tctgaaattc aagtttatga agaaagacaa
     1621 tctaacggac aatggctaaa atccattact tttaagctac caattataga agaaaatctc
     1681 aacataggtt tggacaatga tgaacaagtt gaatgtgtaa gtttattaga gaaacgtagt
     1741 taatcctcaa aaggttcccc gaaccttttg agtcccactg acgcatcaca ctgaggcggt
     1801 atcactgctt gtacgagttg aagcatcagc aaagtaaaag tagatgttca gccaatgcga
     1861 cgaggtgaga ccgaaggtcg ataaggtgtg ttctgggtat aagactcgta aagtaagtag
     1921 gaaatatgat gagatgatac agagagcctg aattggtcag gtgacgtgct tatttacatt
     1981 agcctgataa tgaaaatgga gagattatcg atggttatat tggaattgta ccaaaatgat
     2041 tattctaaag atttagtagc atttgattcc atagaagatg ggaaagcctt tgtagctcaa
     2101 atcccgggat acactctgga aacagaagat ggttttgaag tggagtattt taatcctaaa
     2161 aacataccgg attatatgga aattattttt aacggaaata ttgttccttt atctaaattt
     2221 atgttcgatc ctgaggaaaa tgtaaacatt atttggaaag agatttcaaa tttatccctc
     2281 aaaaatgata gagtgatcga aggatattca aaaattgatg catatgtcgt taacaaccat
     2341 gaagttaaag cctatgtcga aacaagagaa acgaactatc gtaaagcaaa agacttctta
     2401 gaaagccgcg gatatgaaat cgacagaagc tttttcggaa gtgaagacgg tgaagcgatt
     2461 ctttacagaa aaaaagggat cgaagtttgg catttcttgt gtcacttaga cccaatgttt
     2521 gtagagattg aagatgtaga aggatatgtt aaagaagaag ttggagagat tcaatagtca
     2581 accaaagttc cttgtgagta tatacctttg ctagtaaaag agtcaaaacg ttataacgaa
     2641 gggggggaag aaaacccttg agtgtaagtc tttttcttgt ttagagggaa agtattagag
     2701 tagccgctca taatttatac tagatttgat aactgatttg agacagattt tatttctata
     2761 aatattgtga aaatttttta ataccaaaga tttaaagtta ctgtgttaaa aatcctctcc
     2821 acttttaaac taatgtatta taaaagccag ttgacacaag tgttacacct gtgatagaat
     2881 taacttgagg tgatgaaaat ggcaaccgat aaaaatagaa taatgattag cttggatgat
     2941 aaaaatctag agaaacttga aaatttagta gaagatgcta gagatagaag gggaatgcga
     3001 ctaacaaagt cccaggttat tgaattactc ctaaataccg ttgattattt cgatgatatt
     3061 atgggggcta tttactcaaa aaaataagag caaaattgct attatttttt acaaattggt
     3121 gtaacactag tgatatagga gtgatgaaat ggttgtttat attagacaaa gtaaattact
     3181 aagtgaggtt tcaattaata aatacaatgc tcaagtaggt gcctacttac aaggagaaga
     3241 agttatttta tatcaatctt tttctgaaat aaaagagtta acaagtgaag atatagatgt
     3301 agattatata atggagacta gagcattact aaaaatgatg ggcttaaacg ttccggttta
     3361 tgactatcct attgagctta aagagtttta tggtcgaaag atttatgctg gtattttagg
     3421 agagattgtg aatatacctg ataattgggg aaaatttatt aagcctaaag ctggttcaaa
     3481 agtctttact ggaagagttg ttaatggaac ccatgattta ataggtattg gtctaccttt
     3541 cgactatcct atatggatta gtgaggttgt agaattcata gctgaatggc gttgttttgt
     3601 gttagatggt cgcgtattag atgttcgacc ctatacaggt gattatcatg cacaatttga
     3661 tgcaagtgta attgatgaag cgatatcatg ttggaaagat gcgccaatag cttatggact
     3721 agatatcggt gttactcgcg atggcagaac acttgttgtt gaagtaaatg atggttatgc
     3781 attgggaaat tatggcctat ctcctttaaa atcaatcaat tttcatagag ctaggtggaa
     3841 agaaatggta aaaccctatt ttgaaaaaaa tgaaattttt aaaatccaac aggatgttat
     3901 tttctaaaat aaatatggta gataaccaat ataaaaagca tcaaaatgaa caaggaggaa
     3961 tctgatgctt ggagcaatta ttggagatat tgtcggttct gtttacgaat ggaacaatat
     4021 caaaacaaag gactttcctt tatttcggaa ggactgcttt tttacagatg acacggttat
     4081 gacctgtgct gttgcagaag caattatgaa tggtggacaa aaagacgact tcattgacgc
     4141 gatgaagaaa tatggcagaa tgtatccgaa tgctgattac ggtgctcggt ttaatgcgtg
     4201 gctaaacagc gataaccgtg agccttataa tagctttggg aatggatcag ctatgcgtat
     4261 ttctccatgt gcttggatca tggactgtgg tttttatgcg aaaactggta tatggccatc
     4321 atctagagga cttacgagtc tttctgcaga ggtaactcat aatcatccag aaggtgtcaa
     4381 aggcgctatg gctacagctg atgctatctt tctatgtcgt ttttactttg gtggttattg
     4441 tagagagtac gagcaatcaa ttaacgacaa tcctacagag tgtaaaagac gaattaagga
     4501 ttatatagaa aaagaatacg attacaatct atctcaaact ttagatgaaa tccgtcctaa
     4561 ctatcgtttt aacgaaacat gtcaggaaac tgtccctcaa gccattatcg cctttcttga
     4621 aagtagagac ttcgaagatg cgataagaaa tgccatctca cttggtggcg acagtgatac
     4681 tctcgcagca atcacttgta gcatagcaga ggcagcttac ggtattcctg attggatcaa
     4741 ggataaggac tattcttact tggatgaacc cttaaaggat gtagttaggc gatgggaaaa
     4801 tagaataaaa gcgtattaat ctccagtacg tcagatttct cttttctgta ttttcattgt
     4861 ataataggat tacatttact tgcatacgac gaaatgtaaa catttctgtt taaaattaag
     4921 gataaaatca atgaaaaaag caatggtaat tatcaaccct acttctggtg gcgagaaggc
     4981 tttggattac aaagaaaagc tggagaataa agcaaaagaa tactttgaat atgttgaaac
     5041 caaaattacc gaaaaagcgc tggatgcaac acattttgct gaagaagctt ctcgtgagca
     5101 gtatgatgca gtggttgtgt ttggtggaga tggaactgtc aatgaagtca tttcaggtat
     5161 tgatgagaga gactacattc ctaagttagg gattatccca ggcggtacgg gtaacctcat
     5221 tacaaaactt ttggaaatca atcaagacat cgatggcgca attgacgaac tggattttga
     5281 tttaaccaat aagattgata tcggtaaagc aaatgacaac tattttggtt atatctttag
     5341 tatcggttct ctgcctgagg cgattcacaa tgttgaaata gaggacaaaa caaaattcgg
     5401 tattttaacc tatgctgtaa ataccatgaa gtctgtcatg acagatcagg tctttaacat
     5461 taaggttgag acagaaaatg gaaattatgt tggtgaagct agccatgttt tggtcctttt
     5521 gacaaattac ttcgctgata agaaaatctt tgaagaaaac aaggacggct atgccaacat
     5581 tttgattctg aaagatgcct ctatattctc caaattatcc gtcattcctg atttattaaa
     5641 aggggatgtt gtcgcaaatg ataatatcga gtatatcaaa gcgcgtaata ttaaaatctc
     5701 ttcagatagt gaattggagt cagatgttga cggagataaa tcagataacc tacctgtaga
     5761 aatcaaagtc ctagctcagc gagtagaagt attttcaaaa ccgaaagagg attagtatat
     5821 agagaaagcc ttttttaagg ctttttgtat actttaaaag atagttcctt taacaacgga
     5881 cattccttgc aaatagttta caaaaatagt atactggatt cattgagctt gaaaacgttt
     5941 gcgtaaaatt tgaatgaata ctttaggaga caaattgatg gaattgagtg ctatttacca
     6001 taggcctgag tcggagtatg cctatcttta taaggataag aaactccata ttcgaattcg
     6061 aactaagaaa ggggacattg aaagcatcaa cttgcactat ggggaccctt ttatctttat
     6121 ggaggagttt tatcaggata caaaagaaat ggtcaagata acttctggta ccttatttga
     6181 ccattggcag gttgaagtgt cagttgactt tgcacgtatc cagtatctct ttgagctcag
     6241 agatacagaa ggtcaaaata ttttgtatgg cgataaaggg tgtgtggaaa attctctaga
     6301 aaatcttcat gcaattggga atggatttaa gttgccttat cttcatgaga ttgatgcctg
     6361 caaggttcct gactgggttt caaatacggt atggtatcag atatttcctg aaagatttgc
     6421 caatggcaat gctctattaa acccagaagg gactttagac tgggattcat ctgtcacacc
     6481 taagagcgat gatttctttg gtggtgattt acaggggatt attgatcata tggattactt
     6541 gcaagacttg ggtattactg gactatatct ttgtcccatc tttgaatcta caagcaatca
     6601 caagtacaat acgacagatt actttgaaat tgaccgtcat tttggagaca aggagacctt
     6661 tcgggaactg gtggatcaag cgcatcatcg tggcatgaaa gtcatgctgg atgcggtatt
     6721 taatcatatt ggttcgcaat ctcttcaatg gaaaaatgtc gtcaaaaatg gtgaacagtc
     6781 tgcttataag gattggttcc atattcaaca attcccagtg acaactgaaa agctagttaa
     6841 taagagagac ttaccctatc atgtttttgg tttcgaggac tatatgccta agctaaatac
     6901 agccaatcca gaggtcaaga attatctttt aaaggttgcg acttattgga ttgaagagtt
     6961 taatatcgat gcttggcgtt tggatgtggc taatgagatt gaccatcagt tctggaagga
     7021 ttttcgtaag gcagttttag ctaaaaatcc tgatctttat atcctaggag aagtctggca
     7081 tacatctcag ccttggctaa atggagatga gttccatgcc gtcatgaatt atcctttatc
     7141 tgatagtatc aaggactatt tcttacgagg aattaagaag acagaccagt tcatcgatga
     7201 aatcaatgga gagtctatgt attacaagca gcagatttca gaggtcatgt ttaatctctt
     7261 ggattcacat gatacagagc gaatcctgtg gacggccaat gaagatgttc aactggttaa
     7321 atcagcctta gcctttctct ttttacaaaa aggaacaccg tgcatttatt acggaaccga
     7381 gctagccttg actggaggac cagatccaga ttgtcgtcgt tgtatgcctt gggaacgtgt
     7441 atcaagtgac aatgatatgc tgaactttat gaagaggctg attaagattt ggaaatacgc
     7501 gtcagtaatc atttcgcatg gcaagtatag ccttcaagaa atcaaatctg atctagtagc
     7561 tctggaatgg aaatacgaag gacggatcct caaagcaata ttcaaccaat caacagaaga
     7621 ttatctttta gagaaagaag cagtagcact agcaagcaat tgccaagaat tggagaatca
     7681 gcttgtcatc tctccagatg gatttgtgat tttctaaaaa ctagttgatg aagattatgg
     7741 tacatttcat atcttatata gtataataag gctagttact aaacttgtaa aggagaactt
     7801 aaatgaattg tagaggacat gaaacaagac aaagaattgt tagagatttt gaagtttagc
     7861 ctaaagcaca tattaagctg ttagcaaatc aacaaaaaca tagtgatgca ggagcaacta
     7921 ttgaagatga atattatgta tttatcgctg agagtaaaat tgatggcaag aaggaagtta
     7981 ttcagtgttg catgggtgcg gcaagggatt ttttagaact aattaatcac aaagggctac
     8041 ctctttttaa tccgcttgta ggtgattctc atgtaaataa tagacaagaa tatgacaata
     8101 cagggagtga aaatttacaa cctgaaaagt ggaatgaaac tgcaaagcag ctttataatg
     8161 ctataatgtg gttgattatt ttatggaatg ctaagccgga tacaccttta tttaatttta
     8221 aagacgaagt aattaagtat aaaacatatg agccttttga aagcagtata aaaagagtaa
     8281 atactactat aaagaatggt agtaaaggga aaactctgac tgagatgatt aatggctaca
     8341 gagcggataa cgatattaga gatgaaattt gtaactttaa tattctgaaa aataaaattc
     8401 gtgatatgaa agaccaacaa ggaaatacaa tggaatctta cttttagtta ttgttgaatt
     8461 ttgggtattc tataaaatat cctaattgag attt
//
LOCUS       DAVLCS010000065         8278 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLCS010000065 DAVLCS010000000
VERSION     DAVLCS010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.065"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            <1..880
                     /locus_tag="VXC78_001959"
     CDS             <1..880
                     /locus_tag="VXC78_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0583966.1"
                     /translation="GKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHN
                     QKFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLFYPRKGKALKKQASTNFKPAG
                     QSIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVV
                     NQALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIH
                     RWLPKGTKKMTPKEVAFIEKWINNYHKKCLNYKSPREDFLMANLNLKFSVRNKSRNRF
                     KFCRSFKYPARRCSWC"
     gene            852..1496
                     /locus_tag="VXC78_001960"
     CDS             852..1496
                     /locus_tag="VXC78_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV0583967.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(1538..3526)
                     /locus_tag="VXC78_001961"
     CDS             complement(1538..3526)
                     /locus_tag="VXC78_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0583968.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVYFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(3528..4286)
                     /locus_tag="VXC78_001962"
     CDS             complement(3528..4286)
                     /locus_tag="VXC78_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583969.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            4714..4905
                     /locus_tag="VXC78_001963"
     CDS             4714..4905
                     /locus_tag="VXC78_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0583970.1"
                     /translation="MKHKEHILIGFLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(5259..5531)
                     /locus_tag="VXC78_001964"
     CDS             complement(5259..5531)
                     /locus_tag="VXC78_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0583971.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(5590..6039)
                     /locus_tag="VXC78_001965"
     CDS             complement(5590..6039)
                     /locus_tag="VXC78_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV0583972.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQRYQRKRRIDTRRYRCGLCRGKLLLINQPED"
     gene            complement(6026..8155)
                     /locus_tag="VXC78_001966"
     CDS             complement(6026..8155)
                     /locus_tag="VXC78_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV0583973.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVNPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESETFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNINTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         2504 a         1742 c         1614 g         2418 t
ORIGIN      
        1 tggaaaaggg cgcttcaaag aggtttattc tgccgactat gctcaacagt cttatgaaaa
       61 caatcgcaag cgctcggtca agaaatcaag cttgaccaag gaactaaagg aaaagattct
      121 ccactatcat aaccaaaaat tttcgcctga aatgatggtg atggctaaag gggttaacgt
      181 gggaatttca accatttact attggattca tcatggaaaa ttggggttaa gcaaacagga
      241 tctgttttac cctagaaaag gaaaagcgct taagaaacag gctagcacca actttaaacc
      301 tgctggtcaa tccatcgaac agcggtctga agctatcaat cttcgcttgg agaatgggca
      361 ttatgagatt gatacggttc tacttacgag agcgaaaaac tactgcttgc ttgtcttgac
      421 ggatcgaaag agtagacatc agatcatccg attgattcca aataaaagtg ctgaggtggt
      481 caatcaggct ctaaaactca tcttaaaaca acacaagatt ctttccatca cggcagataa
      541 tggaacggaa ttcaatcgct tgtttgatgt attttctgag gaacatatct actatgcgca
      601 cccctatgcc tcttgggaaa ggggaactaa tgagaatcac aacaggctca ttcatagatg
      661 gttacctaag ggaaccaaga aaatgactcc caaagaagtc gcattcatcg aaaagtggat
      721 taacaactat cataaaaaat gcttgaacta caagtcaccc agagaagact tcttgatggc
      781 taacttgaac ttgaaattta gcgtcagaaa caaatcacga aatcgattca aattttgcag
      841 gtcgtttaaa tatcctgcgc gcaggtgttc ttggtgctaa cgatggaatt atttccattg
      901 ctggtgtggt tatcggggtt gccagtgcca cgaccaatat ctggattatc tttttatcag
      961 gatttgcggc tatcttagct ggtgcctttt caatggctgg tggagaatat gtatccgttt
     1021 caactccaaa agataccgag gaagctgccg tttcgcgaga aaaactcttg ttagaccaag
     1081 atagggaact agccaaaaaa tccctctatg ctgcttatat ccaaaatgga gaatgcaaaa
     1141 cttctgccca actcttgacc aataagatct ttcttaaaaa tccactcaag gctctggtag
     1201 aggaaaaata tgggattgag tatgaagaat ttaccaatcc ttggcacgct gccatttcta
     1261 gcttcgttgc ctttttcctt agaagtttgc ctccaatgct gtcagtgacc atttttccaa
     1321 gtgattaccg catccctgct accgtcctta ttgtcggtgt ggcccttctt ctcactggtt
     1381 acacaagtgc tagacttgga aaagccccaa ccaaaacagc tatgattcgg aaccttgcta
     1441 ttggtctctt gaccatggga gttaccttcc tgctcgaaca acttttcagc atttagaata
     1501 caagaaatac ctcgattttg aagtcgaggt atctttttta catttgcaca atcttgcgat
     1561 aacttcttga agtaatcatg aaaatcagca cataggcgat gaggaagata gcgcagatag
     1621 acaaggtcac aatcaacatc atagtcgtat ccagtacacc aatcactttt aaaatcagac
     1681 taagcatatg gtaggcaaag gctagatgta ggaaggcaaa gagcaaagga aggaagtata
     1741 cagttaaaac ctgtttgttg atggtttgct tgatttgctt ttgatctaaa ccgactttct
     1801 gcaagataat aaagcgctca cggtcttcat atccttcaga aatttgtttg tagtagatga
     1861 ccagaacggt tccgaccata aagataatgg ataagaaaat accgataaag aagacaccac
     1921 caaagagggc actcatctga gcactagcat ctgctagagt gctaccatac acatagttac
     1981 cttcagtgtt taattgagca ttaaactttt gtaagtattt ttcatactcc tcagcgacct
     2041 tgagttgttc tgcttcactg gcatttacat tcataccacc gtaaaactga ttatagatag
     2101 ccgaatctgg gaattgatcc aaaaaggctt gtaaatcagg tacaacaagg taattgtaat
     2161 cagcagtcaa aatattaaac tgatttggaa catggttgac aataaaatct ttagtaaatt
     2221 cttcttttac agaaaattga tgatcattta gagttagagc tttctgttct ttaactccct
     2281 cattctttgc aaagagtccg acctcatttc ctgatagaga cagtttttga ccagtcatat
     2341 tttcataatc tttttggtca aataccatga aaactgtttt tggttggaca cggttttgtc
     2401 ctttttcaaa aatagttaac ttggttcctt cttgattcgc aacagcaaag taagtgtaac
     2461 gaaatacttc tttttcttta atcttataac ctttgtcact tgcaaactgg ctcaagagtt
     2521 tgtccaagtc ttctttttca acattttgcc ctgaaacccc aaaatcatga ggatttagaa
     2581 cttttttaaa gctttctgag gaattgaaaa tgcttgtcgc tgctgacatg gttaccaaaa
     2641 ccattgttga caagatagcg atggtggcta gtccaactgc atttttcttc atacggaaaa
     2701 tcaagttaga aacagatatg agattatttg gttggtaata gtatttctta tttttcttta
     2761 agatttggag gaaaacggta atccctgcat taaacaagag ataagtccca aagataacca
     2821 gtaaaacagc tatgaagaag gttgttaagg ctgtaagagg atcttttacc gtaagggcaa
     2881 gataatagcc aattcctaaa cttatggaac caagaatggt ttggagagga aggaagcgac
     2941 cttttttctc tccactagct ttctcacgag agagctggag ggcattcata cgggcgattc
     3001 gaagggcatt caggaacatg aggcctagga aaatcaaacc gaagacaaca agcactgtaa
     3061 tgacaacttt cgtctggaag gtagcaacca gctcaacctt caatttcatt agtttgagca
     3121 ggaaagcgaa aattaacttg tcaaacaagg ctccaatacc gatacccgct ccaacagtta
     3181 gaatcccaaa taccactaac tccttaaagg tcatactgat aagatgacgc ttctccaagc
     3241 ccaacatgcc ataaattcct agttccttgg aacggttctt catgacaaaa ctattggcat
     3301 agagaacgat aatggctgac gcaagggtga cgacaaacat accaaatcca agtgtagcct
     3361 gaatggttgt tcctccacgg atttccgcaa tcttaggatt gaaggttaga gagtaaaaga
     3421 gataggtgac agtgactgcc aagagaacag ccagcgcaaa aggatagtag agtttgcggt
     3481 ttttaatcaa gttcgatacc gctaacttat tggttaatcg aaacatacta attcacctcg
     3541 cttgccatga cagtcaaggt atcagagatt tcttggaaca tctgacgctc tgtcttctct
     3601 ccacggtaga tttggttgta aagaatgccg tctttgataa agagaacacg cttggccctg
     3661 ctagcagctg ctgttgagtg ggttaccatg aggatggttt gcccacgctc attgatttca
     3721 ttaaagacat caagtaaggc tgcagatgac ttggaatcaa gggctcctgt tggctcgtcc
     3781 gcaaggagaa tttcaggttc tgtgatgatg gcgcgggcta ctgctacacg ctgtttctga
     3841 ccaccagaaa tctcgtaagg gtacttctct tgcaattggt tgatacccag attttcagct
     3901 gtcatcacca atttcttcat catctccgtt ataggtcttc ttgacaagac aagcggaagc
     3961 aagatattgt ccttaacaga cagagtatct agcaagttaa agtcttggaa gacaaatcct
     4021 agcttttcac gccggaaact agaagcctgt gaatttttaa tagttgctgt atcagttcca
     4081 tttaagtaaa cctgaccacg acttggtttg tccagcatag ctaggatatt gagaagagtg
     4141 gatttaccag aaccagactc acccatgatg gcaacatagt cacccttttc tacggtaaag
     4201 tgaatatcct tgagggcttc tacttggttg ccctgaaaac gtgttttata aattttttga
     4261 acgtgtttta catctaaaag tgtcatgaga atctcctttc ttaatatccc ataaaatgaa
     4321 atgtagcttg catcatagtg catcccagct gaacgcgctc aatttctttg tgacttggtt
     4381 ttctagtttt cttatgtacg atttgtttca tgatgttact cctttgttct ttatgagtct
     4441 agtttacatc aaaaaaagac cgcttgccat aacctaacct tacaaaagag actttaatct
     4501 tacatttttg taagattggg ggaaatataa gcaaaattac ttagaaaatg atttgatttc
     4561 ctatttttaa agttgtaaaa tataagtgcg aaaaggctta ctttgaaaag gaggaagcgg
     4621 gaactaacat tttagtaagg ttacctagat gacacaccat taaattgaac actttcaaat
     4681 cgaactacct ataaggaaag aaggtgcgct ttaatgaaac ataaagaaca tatactcatc
     4741 ggatttctct atctgctctc tccattcatc ggtcagctct tagttgaaca cacacacttt
     4801 atcggtacag aatttaccgg cactgcttat gttatttgct ggttatcagt tgttatcagc
     4861 atccaccatt tttccaaaaa tgtattgtct cagcagcaaa aatagattaa aaaactgagt
     4921 ttaaattact gcttttatag taaaatgaaa taagaacagg acaaatcgat caggacagtc
     4981 aaatcgattt ctaacaattt tttagaagta gaggtgtact attctagttc caatccacta
     5041 tagtttgtag atgaagctgg cgaaatatta ttaatactat tcaaaaatca aagtgcaaac
     5101 tatatcaact tcacattgcc gactaaatta cagcctgcgg ctggcttcct agtttgcact
     5161 ttgattttta ttgagtataa aagtaaaaaa gctttaaatc aagcagttta gactattgat
     5221 ttaaagcttt ttgcgtattc caaatctttt gtaaaacctc accaaaacca gccttcatta
     5281 tcgtcaatgg cttgagcttc tttgcgttta cgtgggcctg ttccgtacat ttctgcttcg
     5341 atttcttcct tggttggcat gatagaagct aggatgatat agataatcac cccaagtcca
     5401 aagtttgcga ctgtaaaaat ggcaaacaga aaacgtacaa gggtaacatc aaagttccac
     5461 ttgtctgaca gacctgccaa aactcctgaa atcatgcgat ttcgtctcat tttataaaat
     5521 ttactgttca tgatatttcc tctttctgct aggttagaca tagtatatca cgggtaggct
     5581 cggctttcat cagtcctcag gctgatttat tagtagcaat ttacctcgac aaagtccaca
     5641 gcgatagcgt ctggtatcaa ttcttcgctt acgctgatac ctttgctggc aggattggca
     5701 acgatagagc ttgattggct tggagttact attgggcaag gatggtacaa accgtaatcc
     5761 atccactgct ttcaacagtt ccttaaaatc ccgatcctta tgttgatagc ctttcccttg
     5821 aaaatagagg tgataatgac agagttcatg tcgaacaatt ttcctaaaaa cgtccaaccc
     5881 cagttcctga taaaccttgg gattaaaatc caaatgccca tctttgggga aaaatcgccc
     5941 acctgtcgaa cgtagacgcc tattccactg gacatgatgg ataaaaggtc tgccgaagtc
     6001 ttctagtgaa acctgcttga cgtaatcagt cagtttcatt tggagctagg agagacagat
     6061 taactttttc acgttcagta tcaattttct taacccaaac gctcaccaaa tctccaactg
     6121 ccaccacttg actagggtgt ttgataaact tgcgactcat atgggaaata tggatgagac
     6181 cgtcctcatg aattccgata tcaacaaaag caccgaaatc aacaacgtta cgcaccactc
     6241 cttctagctt ttgtccaacc actaagtcct tgatatctag gacatcttga cggagaactg
     6301 gagcatcaaa ggaatcacgg aaatctcgac ctggtttgag aagatctgca atgatatctt
     6361 taagagtttc tggaccaagg tctaactctt gcgccatttc cttgactgaa agcgacttga
     6421 gtttgctttg ggcctcttca ttcaggtcct taatgtccaa gcgtttgaag agttccttaa
     6481 cggcagcgta attttctggg tgaactcctg tattatcaag gatattgcta ctttcgggga
     6541 tacgaaggaa accagctgcc tgttcaaagg ccttagcccc caaacgagga actttcttga
     6601 tttgggagcg tgaagtgatt tttccttcct cctcacggta tttgacaata ttttcagaaa
     6661 tggttttatt gagtccagcc acgtgagaaa gaagagctgg actggccgta ttgatattga
     6721 caccgacttg gttaaccacc gtatccacga caaagtccag actctcagat agtttcttct
     6781 gactgacatc gtgttggtat tgaccgacac caattgactt aggatcgatt ttgaccaatt
     6841 cggcaagggg atcttgcaaa cgacgggcga tagaaatagc agagcgtttt tcaacagtca
     6901 agtctggaaa ctcctgacga gcaagttcac tggcagagta gaccgaagca ccactttcat
     6961 ttacgatgac ataactaacc tcaggaaaat ctttaagaac ttccgccaca aaggtttcac
     7021 tttcacgact agcagtacca tttccgatgg caataatctc tacaccgtat tgaccaatca
     7081 agtccgccaa atctttcttg gcttcttcga tttgacgagc tgatgctggg ttgacaggat
     7141 agatgacctg agttgtcagc atttttcctg ttgcatccac gacagctaac ttggcacctg
     7201 tacgaaaggc tgggtcaaac ccaagaacca cgcgcccttt cagtggagca accaagagga
     7261 gattgcgcaa attgtcagaa aaaagttgga tagctccctc ttcagctttc tcagttaatt
     7321 ctgtccgaat acgacgctca atagcaggca agaccttttt cttaacggat tgctgaacaa
     7381 cttcatcaat ataagcattt ttcaccttga aacgagtagc aaagaaggca agaatacggt
     7441 ccgtcgcatg ttcaaaaccg atcttcaaga caccaagttt ctccccacga ttgagagcca
     7501 aggtacgata gccttgcata gttccaactg tctctgaaaa atcataataa atctgaaaaa
     7561 cctgcttttc atcaagactt tcatccttgg cttgagaagt gagtttagag tgtctcagca
     7621 cttcctgata agtcatagaa cgcaaggtca catcttccga taaggcttcg accaaaatat
     7681 caactgcacc ggtcaaggct tccttgccag tcgcaaatcc ttcacagacg aacttttcag
     7741 cttctttctc taagtcaact atattctgca aaatcaagcg agcaagagga aagagtccag
     7801 cttcacgggc aatggttgcc ttggtacgac gcttttcctt ataaggaaga tagagttctt
     7861 caacgtctgc taatttttcg gcaactaaga tagcttcttc caattccttg gtcaacttgc
     7921 cttgctcttg aatcttagct aagacagctt ccttacggtc attgagattt gtcagacttt
     7981 tatccaaatc aataatagcc ttaatcgcca cctcatccag actaccagtc atgtccttac
     8041 gataacgcgc gataaaggga atagtcgccc cttcagctgt caaacttaga acggtatcaa
     8101 tttgctttaa cgtcactccc aaatcctgag agattttttc atatttttta tccataaatc
     8161 tattatacca caagctggaa ggctttctcc aatccttttc atactcaatg aaaatcaaaa
     8221 agcaaactag gaagctagcc gtaggctgct caaaatactg ttttgaggtt gtggataa
//
LOCUS       DAVLCS010000066         8232 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLCS010000066 DAVLCS010000000
VERSION     DAVLCS010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8232
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.066"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            20..1495
                     /gene="galT"
                     /locus_tag="VXC78_001967"
     CDS             20..1495
                     /gene="galT"
                     /locus_tag="VXC78_001967"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0583974.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLAIKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGKYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPNIKKEEVN
                     SVVQHEVGQAFARVLEDAGVYKNTSSGHEAFMRFVKSVGIN"
     gene            1508..2521
                     /gene="galE"
                     /locus_tag="VXC78_001968"
     CDS             1508..2521
                     /gene="galE"
                     /locus_tag="VXC78_001968"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0583975.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKIDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YNL"
     gene            2702..3361
                     /locus_tag="VXC78_001969"
     CDS             2702..3361
                     /locus_tag="VXC78_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV0583976.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRVTEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVRFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3386..4453
                     /locus_tag="VXC78_001970"
     CDS             3386..4453
                     /locus_tag="VXC78_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0583977.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIPGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSISGLQGGTGRAILASILVRYLDDKGELGVSEKGWEAAKEYLKNAYTL
                     QKGESSIVKMLDKEDPIQYGMMWGSGALVGQKEQNVVFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQTEIQVEYSKNFGSIPANKDALKDLPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            4556..5566
                     /locus_tag="VXC78_001971"
     CDS             4556..5566
                     /locus_tag="VXC78_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0583978.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5578..7269
                     /locus_tag="VXC78_001972"
     CDS             5578..7269
                     /locus_tag="VXC78_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0583979.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7272..7982
                     /locus_tag="VXC78_001973"
     CDS             7272..7982
                     /locus_tag="VXC78_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0583980.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2781 a         1130 c         1606 g         2715 t
ORIGIN      
        1 aaattagaaa gaaaaatata tgaaaacaat tattgataat tttgttgata gagtaattga
       61 atacggaatg tataatgaaa ttgacaaaat atatgtgaaa aatagagtac tagcgttaat
      121 aggtgaggag ggaattgatc gcatttccga tgaaaatgac ctgaaacaaa taaaagatta
      181 cttagtggaa atcgccttaa aaaacggtaa aattaaagat ttaatcgagg aaaaggaatg
      241 tttaggagca gagttaatga atttcatagt tcctttacct agtcgattaa atgatatttt
      301 ttggagttca tatgatatat cacctcaaga agcagttgaa gagttttata agttaagtaa
      361 agatagtgat tatattaaaa cttctgctat tgctaagaat attgagtttc gagcatcaac
      421 taaatacgga gagctagaga ttacgataaa tttgtcaaaa cccgaaaaag atccaaaaac
      481 aattgctgct gaaaaattag taaaagcaac taattatccc aaatgtttac tatgtatgga
      541 aaatgaagga tatcaggggc gaataaatta tccagcacgt tcgaatcata gaattattcg
      601 gttgaaactt ggtgacgaag tatggggatt ccagtattct ccctactcat actttaatga
      661 gcatgcgata tttttgaata gtcaacatgt accaatggct attacctcta aaacatttga
      721 acaattattg gagattgttg atattttgcc aggatatttt gctggttcaa attctgatct
      781 tcctatctca ggaggctcca ttcttagtca taaccactac cagggaggga aacatatttt
      841 cccaatggaa aaagcaaaat ttgagagtga atttcgtttt aaagactttg aggatgttaa
      901 tgctggtatt gtaaaatggc caatgtcagt aattaggtta caaagtgaaa ataaaaatcg
      961 cttgttagat ttagctatta aaattctaaa taagtggaga gaatattcag atttagaagt
     1021 agacatcatt gctatgactg aagatgtccc acaccatacg gtgactccta ttgctcgtaa
     1081 agtggacggg aaatatgaat tagatattgt tctaagagat aatcatacta ctgaacaata
     1141 cccagatggt gttttccatc ctcatcaaga tgtacaacat attaaaaagg aaaatatcgg
     1201 gttaatcgaa gtgatgggac ttgcgatatt accacctcgt ttgaaaccag agttagaaga
     1261 agttggaaaa tatcttttag gagaggataa cgcaattgcg gattatcatt tagaatgggc
     1321 tgatcaattg aaagaaaaat atcctaacat taaaaaagaa gaggttaata gcgtagttca
     1381 acacgaagta ggacaagcat ttgcgagagt cctagaagat gcaggtgttt ataagaatac
     1441 ttcatctgga catgaagcgt ttatgagatt tgttaaatcg gttggaataa attaggagga
     1501 aacaaaaatg gcaatattgg taacaggcgg agctggttat attggtagcc ataccgtagt
     1561 agaattacta aatttaggaa aggaagttat cattgttgac aacctttcaa actctagcat
     1621 cttggtgcta gatcgtattg aagcaattac aggaatacgt cctgtgtttt acgaattaga
     1681 tgtttgtgat aaacaagcat tgagaaaggt atttgaacaa gaatcgattg atgctgcaat
     1741 tcattttgca ggttataaag ctgtcggaga atccgtgcaa aagcctgtga tgtactacaa
     1801 aaataatatt atgagtacat tggcacttgt tgaagtgatg tcagaattta atgttaaaaa
     1861 gattgtcttt tcttcaagtg cgactgtata tggaattaac aatcagtcac ctctaattga
     1921 gacgatgcaa acaagtgcta caaatcctta tgggtatacg aaagtgatgc ttgagcaaat
     1981 tttaaaagat gttcatgtgg cagattcaga atggagtatt gcgttgcttc gttatttcaa
     2041 tccaattggt gctcatgagt ctggtttgat tggggaagat ccctcaggaa ttcctaacaa
     2101 cttgatgcct tatattgcac aagtagcggt aggtaagttg tcagagctaa gtgtgttcgg
     2161 aaatgattat gatacgcttg atggtactgg tgtgcgtgat tatatccatg tagtagattt
     2221 agcaatagga catataaaag ctttagaaaa agtatctgaa aaaatagatg tttatatcta
     2281 taacctaggc tcgggagaag gcactagtgt attacaactt gtaaatacat ttgaaagtgt
     2341 taataagatc cctattcctt ataaaatagt tccaagacgt tcaggagacg ttgcaacttg
     2401 ttatgcaaat gcagacaaag catataagga attaaattgg aggacaacaa aatcgattga
     2461 agacatgtgt agagatacat ggaattggca atcaaaaaat cccaatggct ataatttatg
     2521 atactgtcta tatgagtgct gtattttgga aaaattactt aaacttttaa tgaaatgcat
     2581 atttaatgaa agataaattt ttttaaaaaa tgtttgaaag cgcttgacaa aggaaacggt
     2641 ttcgttatat aatataagca tagatgacac cggtgtcaaa tataaaaaag agggtcttta
     2701 tatgaaaaac ctaacaaaaa ttaagttcaa agaaaatgga gaatttaatc attttccagg
     2761 aaatactgtt gtagcaaatc tttatactaa acaagatttg atggaagttg ttgatattat
     2821 tcaatcacgt tatagagaat taccatttat cgataagttt actttaactc caaggaattc
     2881 tattcacatg actgtaattg aattgttgtg ccatgaaaat cgtgaaacgg agttttggag
     2941 cagtaatctt cctcttgata cacctttaca ggaaatacat gattactttg ctaaacaact
     3001 tgaaattttt ccattgttgg atgaagaaat tcatatgcgt gtaactgaaa tgggaaaaca
     3061 aaacatacta gttgaacctg cagatgaagc ttctgcaaag agattagaag aaattcgtac
     3121 ttatgtctca gaaaaagcag gtgttcgttt ccctaatcat gatagatatc aattccatat
     3181 ttcaattggg tatcttcgga ttcctctaac cgaagaggag gaagaagagt ttactaaagt
     3241 cagagcagaa ttaactgaaa ttttattaga gaagattcca actattactg taaaccgtat
     3301 tgactatact gtatttgaag atatgagaca atttgttcca tatcatgaaa aatttaaata
     3361 aaataataaa aaaggagaac ttatcatgaa aaaaatgaaa gtttggtcta ctgtacttgc
     3421 aacgggagtt gctcttacta cacttgctgc ttgctctgga ggttcaaatt ctacgactgc
     3481 ttcttcatct gaagaaaaag ctgataaaag tcaagaatta gtaatctatt cgaactcagt
     3541 ctcaaatggt cgtggtgatt ggttaactgc taaagcaaaa gaagctggtt ttaatataaa
     3601 aatggttgat attcctggcg ctcaattagc agaccgtgtt attgccgaga agaataatgc
     3661 agttgcagat atggtatttg gaattggtgc tgttgattca aataaaatta gagatcaaaa
     3721 attactagtc cagtacaagc ctaaatggtt agataaaatt gatcaatctt tatcagataa
     3781 agataattat tataatcctg tgattgttca accattagtt ttaattgggg cgcctgatgt
     3841 aaaagaaatg cctaaagatt ggactgaatt aggtagtaag tataaaggta aatattcaat
     3901 ttctggtctt caaggtggta caggacgggc aattctagca agcatcttag ttcgatacct
     3961 tgatgataaa ggtgaattag gtgtttccga aaaaggttgg gaagcagcaa aagaatattt
     4021 gaaaaatgca tacactcttc aaaagggaga aagttcaatt gttaagatgt tagacaaaga
     4081 agatccaata caatatggaa tgatgtgggg ttctggtgca ttagttggac aaaaagaaca
     4141 aaatgttgtt ttcaaagtta tgactcctga gattggtgta ccatttgtaa ctgaacaaac
     4201 tatggtttta agcactagta aaaaacaagc gttagctaaa gaatttattg attggtttgg
     4261 tcaaacagaa attcaagtag aatatagtaa gaactttgga tctattcctg caaataaaga
     4321 tgccctcaaa gatctaccag aagatactaa gaaatttgtt gatcaagtga aaccacaaaa
     4381 tattgactgg gaagctgttg gaaaacattt ggatgaatgg gtagaaaaag ctgaattaga
     4441 atacgtacaa taagaaataa gagttaattt ttatgtccaa gtctctctat tatttctaaa
     4501 tttatagaag aaataaagag aggcttttgg tttagtaata gagggagtta gtgagatgat
     4561 taaatttgat aatattcaaa ttaaatatgg tgattttgtt gcaattgata atctgaattt
     4621 agatatacat gaaggggaat tctttacatt tcttgggcct tcaggatgtg gtaaatcaac
     4681 tactttgaga gcattggtag gttttttaga tccatcatca ggaagtattg aagttaatgg
     4741 aacagatgtc actcatttgg aacctgaaaa gcgtggaatt ggtattgtat ttcaatctta
     4801 tgcgctattt ccaactatga ctgtttttga taatattgca tttggtttaa aagttaagaa
     4861 ggtagctcca gatgttatta aagctaaagt atcagcagtg gcagcaaaaa ttaagatctc
     4921 tgatcaacag ttacagcgta atgtatcaga attatctggg ggtcaacaac aaagggtagc
     4981 attggctcgt gctctggttc ttgaacctaa aattctttgt ctagatgaac cattgtcaaa
     5041 ccttgacgca aaattacgtg tagatttgag aaaagagttg aaaagacttc aaaaagagtt
     5101 aggtattact actttatatg ttactcatga tcaagaggaa gccttgactt tatctgatag
     5161 aattgcagtc tttaacaatg gatacatcga acaggtcggt acaccagtag agatttatca
     5221 taattctcaa actgaatttg tatgtgattt cattggagat attaatgttt tgaccgatga
     5281 aacagtccac gaagtattat tgaaaaatac aagcgttttc ttagaggata aaaaaggata
     5341 cattcgatta gagaaagttc gattcaatcg tgaaactgaa caagatttta ttctaaaagg
     5401 gacaattatt gatgttgagt tttctggagt tacaattcac tatacaataa aagtttctga
     5461 aagtcagatt cttaatgtaa caagtattga tagtcaggct gctattagat ctgtcggaga
     5521 aagtgtggaa ttatttatca caccatcaga cgttctgcaa ttttaaggag gtgcagtatg
     5581 cgtcataaat taaatttaaa agattggctt attcgtttag ggttaatctg gttcttagta
     5641 acatttatta tttatccaaa ctttgatcta gtagtgaatg tatttgtaaa aggaggagaa
     5701 ttttcccttg atgctgtaca tcgtgttcta aaatctcaga gggcacttca gagtattatg
     5761 aacagtttta agttagcatt ttcactcatt attacagtta atgtcgtagg tattctttgt
     5821 gttctattta cagagtactt tgatattaaa ggtgctaaaa ttttaaaatt aggttatatg
     5881 acctctttaa tttatggagg agtggtttta gcgactggat ataaatttgt ctatggtcct
     5941 tatggattga ttacaaaatt tttacaaaat gttatccctt ctttagactc taactggttt
     6001 attgggtatg gtgcagtctt attcattatg acattttcag gaactgctaa tcatacattg
     6061 tttttaacaa atacaattcg aagcgttgac tatcacacta ttgaggctgc tcgaaatatg
     6121 ggagcaaaac catttactgt tttccgaaaa gtagtgttac caaccttaat tccaactcta
     6181 tttgcactta ctattatggt ttttcttagt ggtttatctg cagtagcagc acccatgatt
     6241 gttggtggta aagaatttca aactataaat ccaatgatta ttacatttgc agggatgggg
     6301 aattctcgtg atttagctgc cttacttgca attattttag gtattgcaac tacaattttg
     6361 cttactatca tgaataagat agaaaaaggt ggaaattata tttctatctc taagactaaa
     6421 gcgcctctta aaaaacaaaa aattgcgtct aagccttgga atatcattgc tcacattgta
     6481 gcatatggat tgttcacagt tttcatgctt ccactaattt ttatagtatt atactcattt
     6541 acagatccag ttgcaattca aacaggtaac ttaacattat caaactttac tttagaaaat
     6601 tatcgcttat tctttagtaa tagtgcggca ttctctccat tcttggtcag ctttatttat
     6661 tctattattg ctgcgacaac agcaacaatt ctcgcagttg tatttgctcg tgttgtcaga
     6721 aaacataaat ctcgttttga tttcttattt gaatatggtg ctctacttcc ttggttacta
     6781 ccaagtacac ttttagcagt aagtttatta tttactttta atcagccaca atttcttgtc
     6841 ttgaatcaga ttttggtagg tagtttggta attctactta ttgcatatat agttgtaaaa
     6901 atcccatttt cttatagaat ggtacgtgct attttattta gtgttgatga tgagatggaa
     6961 gatgcagcaa gaagtatggg tgcttcacct ttttatacta tgatgaaggt tatcattcca
     7021 tttattttac cggttgttct ctctgttatt gctttaaact ttaactcttt attaactgac
     7081 ttcgacttat ctgtattcct ttaccatccc ctagctcaac cattaggtat tacgattcga
     7141 tctgcaggtg atgaaacagc aacatctaat gcacaagctc tggtatttgt ttatacaatt
     7201 gttctgatga ttatttctgg aacggtatta tacttcacac aaagaccggg gcgtaaagta
     7261 aggaaataat catgacagcc actagtcttg ggttatcaaa tattgaaata gttgtcagga
     7321 ttgttttatc agtagtcatt ggtagtataa ttggtttaga gagagggagc aaatcccagc
     7381 ctgcaggcat ccgaacttat agtattgttt gtctagctgc atgtttgatt atgatgacga
     7441 atgaatacgt atcttataaa tttgggacag gagatcctac acgattagga gctcaagtta
     7501 tatcaggtgt gggttttcta ggcgctggaa cgattcttat tacagataaa aagaaaatta
     7561 caggtctgac aactgcagca ggcatttggg cttcggcagg aattggatta gctattggag
     7621 taggttttta tgagggagct cttttagtag ccatttctgt ttggggtgtg atatccatgt
     7681 tccaaccact aaaaaaatat ctgcaaaatc gttctaaaat gattgaattg tatatagtgg
     7741 ttaaatctac agaagcctat aatcgtgtat tggtttattg tgcagaaaat ggtatcagaa
     7801 tgaccgattc aagaacagcg tttggagatg ttaattctga cagaattgaa tactttgatg
     7861 ttccggacaa aaaaatagcg tcatttatta ctctggaatt atcaggtaga tttgaacatc
     7921 ttcgactgat ggaagaaatt gctaatattg taggtgttat ttatgtcgaa gaaattagct
     7981 gaaatttagt aaacaaaggg acagatgttt ttgtcctttt gctttttaga tgttttaatc
     8041 atctaatttt tgagtagatt tttgctcaga ggtttttatg aaagattata aaatcaattt
     8101 tgatttaggt aaaatagaat attttgataa taattgtttg atacaagtat acaaatttat
     8161 ttctttttat gatatttgtg aaatggtgtt tgcctttcat ttacctcctg atgagttgat
     8221 aacaaatgtt at
//
LOCUS       DAVLCS010000067         7109 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLCS010000067 DAVLCS010000000
VERSION     DAVLCS010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.067"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            <1..270
                     /locus_tag="VXC78_001974"
     CDS             <1..270
                     /locus_tag="VXC78_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0583981.1"
                     /translation="DELIKYKHLRINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVIS
                     GSAQPQLPITKLKKILLPLPPLALQNEFADFVVQVDKSQFEDTSP"
     gene            complement(242..2260)
                     /locus_tag="VXC78_001975"
                     /pseudo
     CDS             complement(242..2260)
                     /locus_tag="VXC78_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            2346..3689
                     /locus_tag="VXC78_001976"
                     /pseudo
     CDS             2346..3689
                     /locus_tag="VXC78_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            complement(4195..4665)
                     /locus_tag="VXC78_001977"
     CDS             complement(4195..4665)
                     /locus_tag="VXC78_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0583982.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4682..6955)
                     /locus_tag="VXC78_001978"
     CDS             complement(4682..6955)
                     /locus_tag="VXC78_001978"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV0583983.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFAYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         2189 a         1295 c         1424 g         2201 t
ORIGIN      
        1 gatgaattaa taaaatataa acatttacgt ataaattcag gtatggtaat attacgtccc
       61 aagacaccaa atctaaatca gaaatttatt atccatgttt taaggaataa taattatagt
      121 cgagtgatat caggaagtgc tcagcctcag ttaccaatta caaaattaaa aaaaatactt
      181 ctccccctcc ccccactagc cctccaaaat gagttcgcag actttgtagt ccaggtcgac
      241 aaatcgcaat ttgaggatac ttctccttaa ttttaaaatc atcaatcaag gtctgataat
      301 gcttaatact ataatcaatc acctgagcat agtcgctccc tttttcagga tagcggttgt
      361 taaaaatacc tctgatatat tccgcatgat catgattttt agcaaaaata atagttttac
      421 caatttcatc acccgaggct gtctgaattc ctcttgtcat gagttcattt aaaacaattt
      481 ctactgtact tttattgaaa acaaaggaat taaatacact cccatcaata tctttttcac
      541 agctatcgtc ttcaaatttg ctatcaaaat gttccttttc ttcttcggac aaatcatcat
      601 aatgtagacc atccgtaggt agtttcagtt tggtttcgat agaatgatag gctactaaat
      661 atccgtcttt aacagcctct tccaaatcat atgcatatgt tggaacccca ttctccaaat
      721 taaagaatcc ataggtgttt ttatctaaat cttgacgcgg agtagctgtt aagcctacaa
      781 ttcttgcatc aaaataatca aaaatggact tgtatttctg ataaatagaa cggtgagatt
      841 cgtcaattat gataaggtca aaatgcccaa cagtgaaagg gcgttgattt acttcttctt
      901 gaccactaat cgctccaatc atggtcggat aagttgaaaa gaccatgcga cttgattgag
      961 ctccttcttt atcttctaag aagttacaaa cggaaagatc tgggagtaat tttctaaacg
     1021 aatcataggc ttgcttaacc aaggaagttc tatcggctaa gaagagaacg ttttttaccc
     1081 agttatgacg tgataagata tcaactagag aaactgctgt acgagttttc ccagccccag
     1141 ttgccataac caaaagtacc tgtctacgat gattagagaa agcttcacaa acgcttgcaa
     1201 tggcatgttt ttggtagtga cgcccggaaa tatcgtccct aattttacta gaaatatcct
     1261 caagtggttt ttgaagatga cgtctatcca tcactaattg caattcttct tgagagtaaa
     1321 agcctgcaat ctggcggcgg ttcggaccat caagtatata gtgcttcaag ccatttgtaa
     1381 taaagcaaat tggctgatag ccgatatgtt tctcaagagc ttcagcatat tctttgacct
     1441 gtacttcccc tacttctgga ttgacagagg cttttttagc ctctacaatc gctaaaattt
     1501 tcccattttt accataaagt acatagtcac agtaaccaat tcctgaaccg tgcttgagac
     1561 catcaacggc tatctcaaca cgacagtttt cttcaaatat ccatcctgct aaacggagat
     1621 cgatatcaat aaagagcttt cttgtctctg cctcagataa ttgatcaata tggaaaggca
     1681 catcttgccg ttgcgctgca gtctcacgtt tttcagtata agtctcttga acttctacgg
     1741 actgagcagc catctgttca tgaaaatcag gcagttctgg taaactgtct tgtaacttta
     1801 tcatagattg tggagtttct cggtatttga tgtttgctga aagtggtaag cacttctcat
     1861 caaaataacg ctccacaaac tcattgctgt aacaataatc gataaaatta acaaactgat
     1921 acaaatgatg caaagctaaa atcgcttctc gttccttaat ttcaccacca tgagcagcat
     1981 ggtttcccca ccgaatcaac agaactatct gcttgtggag ttcagaatct acgatatccc
     2041 taaaatcatc atcccatact aaagaagata gagtagcacg atagggagct tctaaatatg
     2101 aatcgtgact atatatccaa tggacagcct gctctaaagc acgacgcgcc ataaaggcag
     2161 tagccacagt tgatgtagca atcatattct cagcttcaat gcaaggtttt gaaaaagatt
     2221 catattcgtc attttttaaa agaaagctaa aatttcccat ttttttctca ctttaaacaa
     2281 atagtttagc tatattatac taaatttcaa gctatttctc cacactttta tagctatctc
     2341 acaagcaaat tgcgatttct gtcgatatgt tagatacagg tattgatgta ccagaggttg
     2401 ttaatttagt cttcttcaag aaagtacgct ctaaaactaa gttttggcag atgattggtc
     2461 gaggaacccg tctatgtaaa gatttatttg gacctgagca ggataaggaa aacttcttgg
     2521 tatttgatta tggggacaat tttgattatt ttcgtgcaga tccaagagat ggagagggtc
     2581 gtcacattgt ttcgttgact cagcgtttat ttaatatcaa agtggacttg attcgagaac
     2641 ttcagggact ccaataccaa gaagatcagt ttgcgagagc ataccgtcag cagcttgtct
     2701 cggaacttca aggtcgtata gagagcttaa atgagttgga cttcagggtt cgtatggttt
     2761 tagatacagt ttatagctat aggaaattgg aaagttggca gaatctaact gctgttacaa
     2821 gtgaaaccat tcaaaaaaat ctctctctgc ttttatttga tgaagataaa gaagatgaga
     2881 tggcgaggag atttgatttg tggttgcttc atattcagtt ggggcaactg acagctaaat
     2941 cttccactgt tcatatttcc caagtgatga agacggctag agctctttct gctattggca
     3001 atatcccgca ggtttttgag caggctgaaa ttatcaggaa agtacaggag cctgaatttt
     3061 ggaaagaagt taacttgtct gatttggaaa aaattcgtct tgctattcga gatttattac
     3121 agtttttgga taaaacagac cgtaaaccct actatgttaa ctttgaagat cgtatactct
     3181 ccactgttca cgagaccaca gcatttttgc aggtcaacga tcttcggtct tacaatgaaa
     3241 aagttgagca ttatttgaaa actcatctgg atgaggagtc catttctaag ctataccata
     3301 ataaaaagtt gacatctgat gatatgcttg cacttgaaaa attgctttgg gaaaaattag
     3361 gtagtaaagc agactaccaa agtcattatg aaaataaggc aattccgaga ttggttcgtg
     3421 agattattgg cttagataga gagtctgcca atcgtatttt ttctaaattt ttgtcggatg
     3481 agaatcttaa tgccaggcag atttcatttg taaaattgat tgtagactac attgtagaaa
     3541 atggtttttt agagacgaaa gtgttaacgc aagagccgtt taaatcttat ggttctgttc
     3601 aactactctt ccaacaccaa ctaccagtac ttcgtaatat tgttcaaatc attgaactta
     3661 tcaataatcg agctggagaa gcggcttaaa ttctaaagtg attgccatgc tgagactcat
     3721 ttaaaattaa aaagagtaga aatttatgct atatatgaga agttttatta ggaagaatgt
     3781 catcgttttc ctagaataca gtatcagttg ttaagtggtt gataaatttc aaagtagata
     3841 cttgtaccac gatgtttgtt gatcgagtta ttaacaaaag agctactttg attttaaaga
     3901 aatagaaaac aaaaagccga gcaagaattc aattgcagga gaaaatgaaa taatactcaa
     3961 tgaaaatcaa agagcaaact aggaaactag ctgcaggctg ctcaaaacac tgttttgagg
     4021 ttgtagatgg aagctgacgc ggattgaaga gattttcgaa gagtataaat cttcctagga
     4081 taaagcaaaa cgcatagtat caagggtttt caacacttga tactatgcgt tttctgatgt
     4141 taaagacttt ctaccaggtt ttttaaaagc ataattgtta gttgtagtca tttattattc
     4201 ttcaaagaaa aatggtgggg cgaatttttt cagttcttca aagcactttt gagcagtatc
     4261 tgcatcttca cagatgataa gacagacatc attaccacaa agggtagcga tagcgtcagg
     4321 gaagctcaaa gtatcaatga tagaaccaaa ggattgagcc agtccaggaa gggtttttag
     4381 taggacttgg tgttgaactg ggcgcatcca gacaagggcg tcttccatgt agagttcgag
     4441 acgtttttcc cattttgaga tggaaccatt gttaagaaca taataagcgc tatcttcttc
     4501 gcggactttt gataggttca tatttttgat gtcgcgtgag agggttgcct gggttacttg
     4561 aatgtcgttc tcagcaagaa gggcttgcaa ctcagcctgt gtatgaatct tgttttttgt
     4621 gataagagcg cgtataagtt ggtggcggtg ttctgattta ttcataataa tgtaactcct
     4681 tttagcaagg taaggtaagc atggactgag cgaggtcgac agtcaagtgg tagtctgtat
     4741 tgtcacggat ggtgatttca aagtcagtag tatagaggac taaacggaga gtgtctcctt
     4801 cttttagctt gtaaatagtt ggctgcagtt caaattgaac gtccatccat tcatctgcag
     4861 taatatcctc tactaacagt aaatcatttc tattttgtaa attaaggtaa ccttttgtca
     4921 cgactcgttg tgcctctggt ctaaatggca attcacagag attttccaac atgtgatagc
     4981 gaccgttgtc aatggttcta gcacttaaaa tagctggata aggttgtagg tatttctttt
     5041 gcccaaattc tagcagttgg gcagataaga gccccttgtt tgtactggat ttgatacgaa
     5101 gattgagctg agcgcgaccg tttaggtgga gatctttagt cacaggaagg ttaatagtaa
     5161 tctgattggc tttcccttga tagagctctg tattgaaggt ttggtatgtc ttaccatagc
     5221 gctcaaaatc cttatctggg tactggtttt gaatagcttg ctcttcttga ccaagtgaga
     5281 aggtttcaca gttttcttgc ccaccgaagt tatcaagtga taaccaagtc tgtggagctg
     5341 tattgtcctg ccagataaca gtaggaagtt gaaagtctgt ttcctgtcct agtaatttct
     5401 tggtcaataa ggcatttatg gactcacgga agtcaattga ttgccaattg ttcatgtaaa
     5461 catgggcacc attatggaaa aagagatgct tgtgtatatg agtaggaaga gcatggaaca
     5521 tctggtaaac atgaagtggt ttgacattcc aatcctgaga accatgagta aagacaacct
     5581 ctgcctttac tttatgggca ttgagcagat aattgcggtc atgccaaaac tgattgtagt
     5641 ccccagtttt tcggtctagc tgagctttca ctttttctaa gtcagcttgg tgagcttcat
     5701 tgccacggat atagtcgcca gctaagagat tacgagaata ggttaactca gcaagggagt
     5761 caaagtcctc acctggataa ccacctgggc tagtcaccag accgttttca cggtagtagt
     5821 tgtaccatga tgaaattcct gcctcggcaa tgataacttc taaaccatcg actcctgtag
     5881 tcgcaagacc attggacatg gtacctagat aggaaagtcc tgttgtagca acttttccgt
     5941 ttgaccaatc agccttgact tgacgctggc gcgtgtgatc agtaaaggca cggcaacggc
     6001 cgttaagcca atcgatgaca tttttataag cctcgatttg ctggtagtct ccattagtca
     6061 tgaaacctgt cgagtctttg gtaccaacac ctgagacata gagattggca aagcctctcg
     6121 gaaggaagta gtcgtttagt gtatagctag agttgatgtg agttagcttt tcctcagcct
     6181 ctgctataag ctcagcttta ccttggggtt ggacgagatt tagttgaggt ttctctagct
     6241 caatcttgtg aggaagttta acctcaagct cgccctccat cttgtagaga gccttgtcac
     6301 tagccttgtc attggttccc tgatgataag ggctggctgt catgatggca gggatttttc
     6361 catcaaaacg agggcgaata atgctaacct ttactaggtc tgatagccct ttttggtcag
     6421 tatcgacacg agactcaacg taaacgactt cacgaatgac atcctggtta gaaaaagtag
     6481 ccaaactctt gccgttaaag tagtggtagt cattatcctc cggaataaga ccatcactaa
     6541 caagttggtc gataagagta tttccttttt tggtgcgagt attgagtaac tgatagagat
     6601 tttcaatcaa gtcaccatat ataatgggaa atccagtttc tttacgaaaa acgtcactat
     6661 cttcgaagtc aaccaaataa gcaaagccta aaagttgaaa agcaacagta taaaaaatat
     6721 ctgctgtcag ttcatcttct gattgaaaaa atgtcagcag gtctgttttt ttatcagctg
     6781 ctaggataga aagtgggtag ttggtgtctt gataagtgaa aaagaaacga cgtaaaaagg
     6841 tttcaagtga gtctttgtga ttggctgtat tttgtaaatc aaagccacat ttttttagtt
     6901 cagataagac attttctttt ggaaaattga tataactata ttgattaaaa cgcatagaac
     6961 ctccatatag aatgacagtt aaggttatta tatcaaaaaa aaagcagaaa gggaattgtt
     7021 aacttcaaaa ggaaataatc caataaaaat gaataaagta ctaaattcaa tatagagaac
     7081 agagtaacaa taagaataaa tagataggg
//
LOCUS       DAVLCS010000068         6982 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLCS010000068 DAVLCS010000000
VERSION     DAVLCS010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6982
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.068"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            119..344
                     /locus_tag="VXC78_001979"
                     /pseudo
     CDS             119..344
                     /locus_tag="VXC78_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(1079..2584)
                     /gene="pyk"
                     /locus_tag="VXC78_001980"
     CDS             complement(1079..2584)
                     /gene="pyk"
                     /locus_tag="VXC78_001980"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV0583984.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(2643..3650)
                     /gene="pfkA"
                     /locus_tag="VXC78_001981"
     CDS             complement(2643..3650)
                     /gene="pfkA"
                     /locus_tag="VXC78_001981"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV0583985.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            complement(3733..6834)
                     /locus_tag="VXC78_001982"
     CDS             complement(3733..6834)
                     /locus_tag="VXC78_001982"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV0583986.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLIGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
BASE COUNT         2102 a         1538 c         1218 g         2124 t
ORIGIN      
        1 ctcgtgttag gtagtttatc tctgcaggta gccgcttgat gcaggacgac gatttagtta
       61 tggagtttcc attatcccag acgactacga cccaatcgct tatgtcgtca gcaagtccat
      121 ggagccaaag ataagaaaca gcgactacct atttatcaag aataccccac agattgacta
      181 taataccatc ggcatcttcc aagtagacgg cactaactat gtcaagaaac tccgccaagg
      241 ctacctcaaa aaaactcaat cccgaatact ccgacatcca cctagacgaa agcaaccata
      301 ttcgtaccat cggaaaagtt gtcaggctat atagggagaa ttaaaaaagg gggagaatgg
      361 cgatataaaa caaacagatt ttaaaagatt cgaaaaactt tgaaaaagtt cattctacat
      421 ttcaaaaaaa gaataagtga cctaaaatag attagatttt gttaaacaat agtgatatgt
      481 aaatttagag aaaggcattt aagatcactt tgcaaaaggc aaatactaaa ctagagaaac
      541 cgataaacca gccccttagt tcccatattt tcaggcacac actccttagt acactagctg
      601 agaagaatgc tataatggtt agagtagaac acaaaaacgc taaaacagta aataacatct
      661 agactcacgt aggtaaaaga atggagcaag ctactttgga ggttttaaat accatatcat
      721 taaatcgaaa atatatcaga tcgaatctag acaagtagat tgcgattgct aaaacatttg
      781 tagaaattca tttgactttc taatcaattt atgcatatct tatttcatac tcaatgaaaa
      841 tcaaagagca aactaggaag ctagccgcag gttgctcaaa gcactgcttt gaggttgtag
      901 atagaactga cgaagtcagt aacatatata cggtaaggcg acgctgacgt ggtttgaatt
      961 tgattttcga agagtatcaa tccattatga aagttttgcc ccctttttgc cccctggaca
     1021 aaaaaagagc ccatcataca ggctagaaag ctggatatga taggttttta tatttttctt
     1081 aacgtactgt gcggatacgc attgtgtttg tgcgaacagc ttctcctact ggcacaccag
     1141 caacgataac gatatcatcg cctgactcaa cgagacctgc ttctaccgct ttacgttcag
     1201 cgatttcgaa catatcgtca gttgaagatg gagcatctgt caacattggg ataacacccc
     1261 agttcaacat caagccacgt tctgtcaatt cgtcaaatgt caatgctaag atgtcagcat
     1321 ttggacggta tttagaaatc aaacgtgcag tatgacctgt cttagtaaga gttacaacca
     1381 atttgatatc cattgagcta gtagcatctt taacagcaga agccattact tctgtcttag
     1441 agttacgctc aaatgaatct gaatcaagac gtccgtattc attaagaaga gcttgagcgt
     1501 tcttgtcgat tgtagccatt gtagttactg actcgagtgg gtatttaccg tttgcagact
     1561 cgcctgacaa cattgtagcg tcagttccgt cgataacagc gttgaatacg tctgatactt
     1621 ctgaacgagt tgcacgtggt ttttcagtca ttgtttcaag catgtttgtt gcagtgataa
     1681 caactttacc tgcagcattg actttcttga taatcatttt ttgataaact ggaaccattt
     1741 cgaacggtac ttcgataccc atatcaccac gagcaatcat aataccatca gctgcttcga
     1801 tgatttcatc taagttatcg ataccttgtt ggttttcgat tttagcgaac aattgaacat
     1861 gtccgtttcc agtttcttca cagattgcac gaacttcgtt cacatctttt gcagtacgta
     1921 cgaatgaaat tgcgatgaag ttgatacctt gttcaagacc gaaacggata tcgtcgttat
     1981 cgcgttcagc aagagctggg aaaggaattt tagtgttagg gatgttcaca cctttttgtt
     2041 tagcgatgat accatcgttt tcaacttcaa cttcaaattc acgagttgca tcatctttag
     2101 caaccacacg aagaccaagt ttaccatcgt caaccaaaac ttgacgacca acttcaacat
     2161 catcatagat atcaagagca ccagcaacgt tcaacgcaat cacttcacga gttgatttga
     2221 ttccttgttt agttgcaaca cgaatttttt caccagtttt gtatgaatat tctttagctt
     2281 caccttcgaa caattctgta cggatttcag gtccttttgt atcaagaagg aaaccaactt
     2341 ttttacctgc aattttttcc gcaagtttaa cagttgccat acgctcacct tgttcttggt
     2401 ggtcgccgtg tgagaagttg aatcggaatg tgttagcacc agcttcaatc aatttagcaa
     2461 tgtttttagc tgaagcttca acatcaagtt tttcacccca gtatccgtcc tcaccgaatt
     2521 ttttaccacc acggatttct accgcaggac ccaaagttgc aacgatcttt acacgtttgt
     2581 tcatgatttt tgtgactcct ttatatatat gacctttttg gtcttattaa ctaaattgta
     2641 aattatgaca agctcttatt caagctagat agctcaatat cggctttgtg cgggttgtta
     2701 accacaatct taccttctgc agtaaggcta aacaatgccc cttcttctgc agtaccaaga
     2761 attggatttt caaccatttt ttcgttacga ataccaaccg caacaccacc gataccttct
     2821 ttaagaagtt taacagcatg tgcacccata cgtgacgcca aaacacggtc acgcgcagtt
     2881 ggagaaccac cacgttgaat atgtccaagt tctgttacac gaaggtcgct tgtatctcca
     2941 gcttctttaa gtttttgacc aaattcagcc gctgacatca caccttcagc taagacgatg
     3001 atattgtgtt ttttaccaca ttcataacca gctttgatgc ttgctacgat atcttccatc
     3061 ttgaagcctg cttcagggat gatgatttca tcagcaccag ttgcaatacc agcccaaaga
     3121 gcgatatcac cagcgttacg tcccataact tcgattacaa aagtacgacg gtgacttgat
     3181 gatgtatcac gaatcttatc gatagcgtcc atggcagtag taaccgctgt gtcaaaaccg
     3241 attgtaaagt cagtaccaac gatatcgtta tcgattgtac ctggaagacc aatagctggg
     3301 aagccatgtt cagtcaaacg catagcgccg tggtaagatc cgtcaccacc gataacaact
     3361 acaccttcaa ttccgtgttt tttcaattgc tcaatccctt taagttgccc ttcaagttga
     3421 gcgaactctg gataacgagc tgagtgaaga aaagtaccac cacgagaaat gatgtcccct
     3481 actgaagctg catctagggg atgaatttca ccggcaacca taccagcata tccgtcatag
     3541 ataccaaaca cttccattcc ttctgaaatt gcttgacgaa caactgcacg gatggcagcg
     3601 ttcataccag gtgcgtctcc gccactagtc aaaacagcaa tacgtttcat attggtttat
     3661 gctccttttt cttttaacat tcttcttgat tatatcacat ttgattttaa aattcttcta
     3721 ttttccgtat ttttagcgat aaatcgtttt cataacgatt tcattcaatt tctcctctaa
     3781 ttcattggat ttagctacaa aatgatgggg agaaacgatg gttttctgtt cctcttcata
     3841 ccggatgatg actgggattg ggcctttaaa ttgttctaaa atgcgtgaaa tttcttgatc
     3901 cgattcatga tttttcacct gtatccaaaa gcgttcagca actgcttctc ttatttcttg
     3961 tgcaatcatt tgcagacggc catcacgtga ttgtattttt ccttttacat agtagaaggc
     4021 tccctctttt atttcctgtc caacctgacg atataagtct gaaaagagag tgacatccaa
     4081 ttttttctta ctatcatctg cctgtaagaa ggccatattt tcaccctttt tggtacgaat
     4141 cacttttatt ttctgaactt caaccaagat aatagcatag ctattttctg acaaatttcc
     4201 gattggggta atcgggtaaa tagccttact tgcaatagct tgtagtggat gtttgctgac
     4261 acctatccct aaaagctctt gttccatata aaatttttct tgttccgtcc aatcttccga
     4321 ttcctgccaa ctataaatag catctccaaa caaacttccc aactctttca caaattcaaa
     4381 tagattagct aaattattaa atactttttg acgatttttt tcaaatgaat cgaaaagacc
     4441 aacttttacc aaaggttcta gcagaggaag tttcagataa ttctcaggta atttagctat
     4501 aaaatcttca atgttagaat aaggtctatt ttcaataatc cagagagcta aatcattact
     4561 gactccttta atggatttca aacctagata gatggccttg ttggcaattt tatcgtgata
     4621 gggaatggtg ttgatggata gagaggctac ttcaaaacct gcttcaagtg catctattaa
     4681 gtaatcactg ttggaagaat ttaacatgac ctgataaaaa atggctggat aatgtgtttt
     4741 aaaataagcc aactggaagg ccaaggctga gtaggcatag gcgtgtgacc tgttaaaacc
     4801 ataacctgca aacttctcca taacatcaaa gacctgctct gctttttcca cagtatgacc
     4861 agcttctaat gaaccttgaa taaaggaagc cctcatctca tgcatggcag aggcatcctt
     4921 tttccccata gcccgacgca aaatatcggc tttcccaaga ctaaatccgg caaatcgctg
     4981 ggcaacctgc ataacctgct cctgatagag cattatgccg taggttggag ccaaaatatc
     5041 ctccagtact ggatccagaa cagtcacttc ttcctgccca tgctttcttg ccacaaaatt
     5101 attgatatag tcactagcac ccggtcgatt tagagaagta gtcgcgacga catcttcaaa
     5161 acagactggt tgcacacgct taagcagacg aatggcacct ggttgctcaa attgaaagat
     5221 accttttgta tttccagagg caaataaagc taacgtttct ttgtcttcca aatctatttc
     5281 ttcaatttta aggtgaatac cttctatttc agcaagcaac tcttgcatct tctggacaaa
     5341 ggtcaaattt cgtagtccca gaaagtccat cttcaaaagt ccgctagcct caactccatg
     5401 agcatcatac tgagtcagtg gaatttcatc accatacttt agaggaatat agttggttaa
     5461 atcttggtca ctaattacaa caccagccgc atggacagag gtttgtcttg gatagccctc
     5521 tatcttgcaa gcaatctcaa aagctttttg gtattctaac ttactattga tttgctgacg
     5581 aaactggaga ttgccctcat aggccgactt aagattgtca cgaaaactga ttttcttagt
     5641 aattgcagat aattcatact ctggcacacc aaagcgtttc aagacatctc gaagagcttg
     5701 cttggctcca aaggttgaaa aagtaacgat ttgtgccgca tgtttactac catatttatt
     5761 accaacatat ctgataaaat ctggacgata aatatctggg atatcaatat caatatcagg
     5821 catggtatag cgttcacgat taagaaagcg ttcaaaaatc agatttttct ctactgggtc
     5881 aatccccgtg atgtctaagg cataagaaac caaactgcct actgcagaac cccttcccat
     5941 tcccatataa tagccattcg atcgtccaaa acgcaacaaa tcccaaacaa ccaagaaata
     6001 atcatcaaag cccatatcat gaataacaga caattcttgg tctagtctat cttgatattc
     6061 tttactagtc aaccccttct gaacaagccc cagttcagca cgctctctca actcctctac
     6121 tgctggtcta gctggattaa aacgaggcag tttcagacta gtatccaagt cgtaagaaat
     6181 gcctgaaata agcttttcta aattgtccaa agcttgcgga aaacactctt ggaatagttt
     6241 ctctaaagaa cttgctgata taaagacatc ttgtctcgaa cgcaagggaa cttctctgag
     6301 cggtagattt tctttaatcg ctgttaaaac ttgaagaact tctctatccc tgctttcaaa
     6361 agcgttgacc cgataaagag gtaagatagg atgatgaaat tcgcttgcta gtgtttctgg
     6421 ataaacccct atatagtaat cacagcctag ttctaacgac tcaactctat caaaataagg
     6481 cacaatgacc gcgatatcct ccaggtactg ggacaggact gaccaagttt tctccccctg
     6541 catcttggct gtcgaaagct tcatcaactg ctgatagccc acactagata gagctaaaaa
     6601 gcgcaaattc acttcctgat catctacaaa cactgtcatt tcaagcccta tcaaaggatg
     6661 aatgccgtat ttttttgtaa tctctagaaa gtcgaaagcg ccataaagat tgtcaatatc
     6721 catcatagcc aaatgagtgt agccgtattc tttagctgct ctcacatact tttcgatcga
     6781 aatgacgctt tccataaaac tatagactgt ttttgtatct agttgtgcga tcaatttaca
     6841 cttctcctct atccttctca ctatattata ccattttcac ctataaatgg cttctcttga
     6901 gaaaaatttc atcagcttac taatttattt tctattcatt tgtatttttg tcatcatttt
     6961 tatatttata ctatattgta ta
//
LOCUS       DAVLCS010000069         6969 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLCS010000069 DAVLCS010000000
VERSION     DAVLCS010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6969
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.069"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(102..377)
                     /locus_tag="VXC78_001983"
     CDS             complement(102..377)
                     /locus_tag="VXC78_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV0583987.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(484..1323)
                     /locus_tag="VXC78_001984"
     CDS             complement(484..1323)
                     /locus_tag="VXC78_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0583988.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1464..2312
                     /locus_tag="VXC78_001985"
     CDS             1464..2312
                     /locus_tag="VXC78_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0583989.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2405..3322)
                     /locus_tag="VXC78_001986"
     CDS             complement(2405..3322)
                     /locus_tag="VXC78_001986"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV0583990.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3760..3965
                     /locus_tag="VXC78_001987"
                     /pseudo
     CDS             3760..3965
                     /locus_tag="VXC78_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4276..4569)
                     /gene="rpmA"
                     /locus_tag="VXC78_001988"
     CDS             complement(4276..4569)
                     /gene="rpmA"
                     /locus_tag="VXC78_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV0583991.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4586..4930)
                     /locus_tag="VXC78_001989"
     CDS             complement(4586..4930)
                     /locus_tag="VXC78_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV0583992.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4946..5260)
                     /gene="rplU"
                     /locus_tag="VXC78_001990"
     CDS             complement(4946..5260)
                     /gene="rplU"
                     /locus_tag="VXC78_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV0583993.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5296..5383)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5442..6146)
                     /locus_tag="VXC78_001991"
     CDS             complement(5442..6146)
                     /locus_tag="VXC78_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV0583994.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     gene            6549..6848
                     /locus_tag="VXC78_001992"
     CDS             6549..6848
                     /locus_tag="VXC78_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV0583995.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2194 a         1411 c         1162 g         2202 t
ORIGIN      
        1 gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa gcctactgac
       61 caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac agcgtcttta
      121 agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat ttctttacca
      181 gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt accaaaaccg
      241 atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa tacagcttca
      301 actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt agcgatcaaa
      361 tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac aaatataatc
      421 atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat tttatttatt
      481 tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt gagtttgaat
      541 aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta agctttcttt
      601 catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg ctacagcacg
      661 ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag ttccacgacc
      721 tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga tattgagaag
      781 agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat tttccaaagt
      841 tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgag ataaaattgc
      901 ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga atttcagggc
      961 ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc tagcaccttg
     1021 gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa gaatctggcc
     1081 accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg gctgacttgt
     1141 tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt ctttcaaatc
     1201 cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg taatatctaa
     1261 ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct taatttttgt
     1321 catagtatca atctttctat tttaggattc agattggttt ccttacttct aattatatca
     1381 aaaaaagatt aaaaatccta atggagtcaa tcaaattttc cgtaaaattt gatataatca
     1441 acttataaga aaagaggtgt cctatgatta aaaaaattta ccccattttt accattttac
     1501 taggtgctgc tatttatgct tttggactga cttattttgt agttccccat catctctttg
     1561 aaggaggggc gacaggcatt accctcatca ccttttatct ttttaaaatc cctgtttccc
     1621 tcatgaacct gctgattaat attccccttt tcatcctagc ttggaagatc tttggagcca
     1681 aatccctcta ttctagttta ctaggaacct tagctttgtc cgcctggtta gctttttttg
     1741 agcatattcc ccttcatatt gatcttcaag gtgatttact aatcacagcc cttatagcgg
     1801 gaatcctatt gggaattggc cttggaatta tttttaatgc tggaggtaca actggcggaa
     1861 ctgatattct agctcgtatt ctcaacaaat acactcatat atccatagga aaactgctct
     1921 ttatcttaga tttttgtatt ctcatgttga ttctcctaat cttcaaggat ttgagattgg
     1981 tttcctacac gcttttgttt gattttattg tttctcgtgt tattgatttg attggtgaag
     2041 gaggatatgc cggcaaaggc tttatgatta tcacaaaacg tcctgaccaa cttgctaagg
     2101 cgattaatga tgacctcgga agaggtgtta cttttatttc tggtcaaggc tactatagta
     2161 aagaaaattt gaaaatcatc tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg
     2221 aaatgattca tcgaatcgat cctcaagcct ttataactat tacagaagcc catgaaatcc
     2281 taggagaagg cttcaccttt gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt
     2341 tagactaaat catctatctt ttgggttaca gacaacctct tttttgtttt atttactcaa
     2401 gctcttaaga ccaattccga gttacttctt catcagcctt taactgatcc actaattggt
     2461 caactgagtc aaatttggtc atatcacgaa tgcgatcaag ccaataaacc atgacggttt
     2521 ccccataaat atcttgatta aaatcaaaaa tattgacttc aaaacgtgct tcttctccat
     2581 caaaggtcac atttttcccg acactagcca tagcacgata cttctgtctt tgaatctcaa
     2641 catcaacgac ataaacgcca tctgctggca tataagtacg gtctaaaagc actaaattcg
     2701 ctgtcggata accaattgta cgaccacgag cattaccatg aaccaccata cctcttgatg
     2761 gaagcggtgc ccccaaaagt tttcctgctt ctttcacatt tccatctaaa atagcttgac
     2821 ggatacgagt tgaactaatc tttcctttct catcttctac aggtggaaca atgataactt
     2881 ctccatcaaa gtaatccttt aaatcttctg ctgttttttt gtcagaacca aatgtataat
     2941 caaaacctgc aacaataatt ttggcattca tagccttgat ataagttgca aagaattctt
     3001 gtgcagtgag actagcgaat tgactactaa aatcaaggag atataattct tctacacctt
     3061 cgcgctttaa ttttctttca cgttcagcag ggttcaaaat atgcaaaaac aaatctggat
     3121 gataaggctc taaagcgatc tttggagatt cattaaaggt cataacgacg ataggtaata
     3181 aatcctttct cgcagccttg ttggcaacac gaaataattc ttgatgcccc ttatgtatgc
     3241 catcaaaata gccgagaaca acgactgaat cagatggtgt gccaatatct ttttggtttt
     3301 ttataggaat agtaataatc ataaaataat tatatcatag cgatagctat ttctggaaca
     3361 gaaaatctga aatgttgttt ttttcacatg aagtgtacct gttttcaaaa agcactttat
     3421 tctatcgttg cttaactatg aactttgcaa tattcttctc aaaaacttgt aggacatctt
     3481 caaaattttg caaggagtga ttagacttgt tcggtaacca taaagtgtca tactatgctt
     3541 atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat tggtgccgaa
     3601 aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa tgagacaact
     3661 tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc actttccctg
     3721 atgacaaaga aaaaagccaa aacagcaaag aaaaactaga tgactgcttt ccaacaactc
     3781 ccatctagtg tgcttcagac taggctattt ttctctccat ctgttagctt ggattctcag
     3841 accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa accattcaga
     3901 caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat agtcaattga
     3961 aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt gttctattcc
     4021 agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag gctgtacttg
     4081 agtacggcaa ggtgaaattg acgtggtttg aatttgattt tcgaagagta tcaatccact
     4141 atacatatta aaaagtatgg gtatcaaaat aaaaaaacag gctctccgaa aactcggaaa
     4201 gccttatttt aagctgtttc tagcttcctc acctttacat ttcaaggttc gggataaaag
     4261 gttcaatgaa cctttttatt ttgcgattgg gtaaacagaa acttgttttt tatcgcgtcc
     4321 tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt ctccaccacg
     4381 accaacgttt acacctggat agatgtgtgt accacgttga cggtaaagga ttgatccacc
     4441 tgttacagtt tgtccgtcag ctgctttagc tccaagacgt tttgcttgtg aatcacgtcc
     4501 gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt taagagtcat
     4561 ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt tggacgaact
     4621 cagaagagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag aataactggg
     4681 tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga tagccacctt
     4741 catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata gaattgataa
     4801 agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat tcgccactct
     4861 cggcgtgtcc agtaatttcc gcactcctca gctcgccatc ttcggctctc tcaaagactg
     4921 cctgtatcat gtgttctcct taaaattaag cgttgattgc gttgatgaca acttttgtat
     4981 atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac ttgtaagtaa
     5041 ccactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct ccagcaacaa
     5101 gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta aaagtaactt
     5161 cttgaccagc ttcaacgttc aatttttcaa cgtaaactgc ttgaccaact tcaactttaa
     5221 cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc ctatgatttt
     5281 tatgggtttc cccgattttt tgtgaagact cgcctagcat cgtgggacga accacttaaa
     5341 cttgaataat caagcaacga tgttcgtgcg gttgcacagg atcgtgcata gtcaactctt
     5401 caagtatagc atatctccta ttttcttaca agtaataaca cctaaaatga agctttttct
     5461 tttacttttt tctgccaaga ggcaaaaagc atgctgaggt aaaaaacgct catcataata
     5521 ggaacaccaa gaatggtctt ttcatgatag aaaatcgtca aataggctga aaagacaacg
     5581 ccaaggacaa aactactaag caggctaaca aatatgaatc cttcacgcaa aaaaggagtg
     5641 tgcttggttc ggaaataatc tccaaaagcc agcatggtcc gtttgatatt ccctgtcata
     5701 aaagcgttat tataggcaat acccgacact tctccaaaag cagttgtcac cagtcccata
     5761 cagaaggcca agggcggcac tagatagata ttatccacag tttgcggcac aaaagcaata
     5821 atgattgata agattgccaa gggaatcaag gacagaatag gttttttcac aattctcaat
     5881 ttttccttat aaatcgttaa taaaaagact cccatcataa acgctagcaa ggtgagaacc
     5941 ttgtccctaa catccgaaac attattttta attaattcta ctgaaagaaa gacaacattt
     6001 ccagtttgtc cagctacaag ggtattcccg cgaacaataa aagtgtaagc atccacatat
     6061 ccagcacaaa acgtcaaaaa aagtgctaac cttttagact gacgtgatat ttttcttata
     6121 ggtaataacc tcattttacc tcccattgta ttttctctta gaaatattgt accattttct
     6181 ttctaaaaaa tcgtaggcta ccatttagat tttactatta gcataaaaat aataatagac
     6241 aactatttat ccaaaaatag atagatgtaa catgtttgca aacaaagcat acgaaccttt
     6301 agtaaaatca tttccatgaa actagaatag agccctctta gcaaaaatca ttattttaat
     6361 ttatttctaa tcactccttg acataaataa ctctcaccaa taaaagacta tgtcttaaaa
     6421 aaaatggtat aataaaatca atacttgggc ttgatggcta tgctactaat aacaattagg
     6481 agagaaaatc aggcacttgt taacaacaag gattatcccc ttgagatgaa aggaacttta
     6541 gaaatcttat gatgaacatg caaaacatga tgcgtcaagc acaaaaactt caaaaacaaa
     6601 tggaacaaag ccaagctgaa cttgctgcta tgcaatttgt tggcaaatct gctcaagatc
     6661 ttgtccaagc gaccttaact ggcgataaga aagttgtcag cattgatttc aatccagctg
     6721 tcgttgaccc agaggacctt gagactcttt ctgatatgac cgttcaagcc atcaactctg
     6781 ctcttgaaca aatcgatgaa actaccaaga aaaaactggg tgctttcgct gggaaattac
     6841 ctttctaaaa acaaggagct agaacaatgc ttgtcgataa caaaggctaa gaaaggtgca
     6901 aaaatgactc tataatattt gtagtgggta aatccactat agatattatg gagcctattt
     6961 tattgtaga
//
LOCUS       DAVLCS010000070         5573 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLCS010000070 DAVLCS010000000
VERSION     DAVLCS010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.070"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(98..2356)
                     /locus_tag="VXC78_001993"
     CDS             complement(98..2356)
                     /locus_tag="VXC78_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0583996.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VXC78_001994"
     CDS             complement(2585..2815)
                     /locus_tag="VXC78_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV0583997.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VXC78_001995"
     CDS             3005..3688
                     /locus_tag="VXC78_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0583998.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRLKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VXC78_001996"
     CDS             3688..4422
                     /locus_tag="VXC78_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0583999.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VXC78_001997"
     CDS             4576..5433
                     /locus_tag="VXC78_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV0584000.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIELEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
BASE COUNT         1551 a         1047 c         1249 g         1726 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata cggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggtccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt catccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttggtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc caacttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg agggcaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ttaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcagt caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccac ttttatttgc
     3601 agcattttac tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggcatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag cttatctttg agggagtcga tattacggac
     3901 aagaagaatg acctgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gatggaaaat attaccttgt cacctatcaa gactaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc agcaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatac aatcaggatc cagcttggca tgggattttg
     4861 gttcagttgc cattaccaaa acacattgat gaagaggcgg ttctattggc tattgaccca
     4921 gaaaaggatg tggatggttt ccatcctcta aatatgggac gcctttggtc tggacatcca
     4981 gtcatgattc catcaacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgaa
     5041 ttagaaggta aaaatgcggt tgtcatcggt cgttctaata tcgttggaaa acccatggct
     5101 cagcttcttt tggccaagaa tgcaacagtg actttgaccc actcacgcac ccataatctt
     5161 gctaaggtgg ctgctaaagc agatattctg gtggtcgcaa tcggtcgtgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggta gtcattgacg ttgggatgaa tcgtgatgaa
     5281 aatggtaagc tctgtgggga tgtggattat gaggcagttg ccccacttgc tagctatatt
     5341 acgccagtcc ctggaggtgt cggccctatg accattacta tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaaa atcgctgaag agagtgtatt
     5461 ttctatagct atatttaaaa tggcagaaat gaatattaaa ttttagatat aagattacaa
     5521 aaggaggtct gcgcctcctt tttgttgtat aatggagtga ggtgattaga tga
//
LOCUS       DAVLCS010000071         5566 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLCS010000071 DAVLCS010000000
VERSION     DAVLCS010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5566
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.071"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            108..407
                     /locus_tag="VXC78_001998"
                     /pseudo
     CDS             108..407
                     /locus_tag="VXC78_001998"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(685..1455)
                     /locus_tag="VXC78_001999"
     CDS             complement(685..1455)
                     /locus_tag="VXC78_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV0584001.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGYLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(1470..2096)
                     /locus_tag="VXC78_002000"
                     /pseudo
     CDS             complement(1470..2096)
                     /locus_tag="VXC78_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
     gene            complement(2002..2604)
                     /locus_tag="VXC78_002001"
     CDS             complement(2002..2604)
                     /locus_tag="VXC78_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0584002.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSTGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGRKGGISSSCWGSVVVTSSERLLETSLR"
     gene            complement(2614..2931)
                     /locus_tag="VXC78_002002"
     CDS             complement(2614..2931)
                     /locus_tag="VXC78_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0584003.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(2948..3265)
                     /locus_tag="VXC78_002003"
     CDS             complement(2948..3265)
                     /locus_tag="VXC78_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0584004.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(3280..4176)
                     /locus_tag="VXC78_002004"
     CDS             complement(3280..4176)
                     /locus_tag="VXC78_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV0584005.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(4179..5441)
                     /locus_tag="VXC78_002005"
     CDS             complement(4179..5441)
                     /locus_tag="VXC78_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0584006.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         1907 a         1213 c          784 g         1662 t
ORIGIN      
        1 agtttctata gtaaaatgaa ccaaaaatag tacacgttgc ggtataatgt tcttgtggca
       61 tattcattag attttcgtaa aaagttctct cctatttgtg agcgaacagg tatagtcaat
      121 tgattgtcag tttgaagacc aagagtcgta aggcaaagga tatggcagaa tccatccaag
      181 ggtggctggc acaatttcta gtgaacctct ttaaatctat tacgtttgac tgtggaaaag
      241 agttttcaaa atggaaagat atttccaatc atcacgatag tgagagcttt tttgcgaatc
      301 taggatgtcc aagacagcgg tgtctcaacg aacattcaaa tagactttta aggtgtcatg
      361 acttgccaaa gcagacagat ttcaacgaag tcagtcaaga attttaggct gggtaaaaac
      421 tcaatttcag gagaaaatga aataaatatt cccacaataa aacgcatagt atcaaagttt
      481 ttccaacacc tgatattata cattttttaa ttttaaagac tttttcccag cctcaagaaa
      541 tcacatccca cctaaatcct ttggatacca aatacctcat caggtatttt ctgagttggt
      601 aagactgtct agcttaattt gacaaatgga gggcgttaaa tccagttttt acaggaagtc
      661 tatttaaata ttttcacact gaccttacaa aatatgaaat aaattatata aagtcattcc
      721 catgacaaag aataacatcc ctttaaaaca gtatcttacc caattttcag gtaagacttt
      781 tgatacaacc gtccccaata cccctccgca tatagaagca agaaaaataa ctggaacagg
      841 tgctaaatga tactgattta aacctgtaac cacaacaatt gtagccaaat gagacagctg
      901 ggaaaagaaa ataattgcaa gagaatacat cgttgcttct tttatcgaaa tagaaaaaaa
      961 caccatcaat aaagatacat tgagcggacc accaccaatc cctaaaaaac tagaaatcaa
     1021 gcccaataga agaccacaaa tcatatagaa tcctatctta tcaaattgat aagttttttt
     1081 aaaatctgtt aaaacaaatg atacaagtaa catcacaaat agtaaaatca tttgaacaat
     1141 agatactagc cgtactgata attgagataa caaaacttga aaaataagat aacctagaaa
     1201 tcctcctaaa acagaagaaa aggataccgt aaaaatcaat ctccatttta tctctttact
     1261 ttgtgaaaat cttttgattg ttgaaataat cgccattata aaaacagaga aactagaata
     1321 aaaagcaata tcactgaccg aatggtatcc aaaactatcc ataagtggct taattataat
     1381 tccaccaccc atgcctgata tagaacccaa tccactagct attataatga ttagaaaata
     1441 aataatctca accacttttt aagtccatcc tattctttca aacatctaaa acctagatgg
     1501 ctactagtgg aagtagaaat acatccattt ctagcagcta ctcggtatcg attacaataa
     1561 gaacaatgac ataaaaagga acctcctctg atagcatact cctcatcttg tatcccatat
     1621 tttggtaact catagtcatc ttcattaaaa ctagctaata aggtatatct cggattgcga
     1681 caccattccc aaacattccc aatcatttga tatagaccaa aatcattagg taaaaattca
     1741 tagacaggag ccgttcctat aaatccatct aaggcagtat tttcataagg aaatcttcct
     1801 tgccaagtat tggcatgata atatccacct tctaaaagag tatctcccca aagatattca
     1861 gattgtcttc ctcctctagc agcatattcc cactgtgctt cagtcggtaa agacattccg
     1921 ctccaattac agaaagccaa tgcatcttct aaagcaacat gaactactgg atggtcttct
     1981 aaacccacta gattactgtt ctcaccgtag ggatgtttcc agcaagcgtt cggaacttgt
     2041 aaccaccacg gagccccagc aggatgagga tatccctccc tttctgcctc tggcattaat
     2101 atggtttcct ggaatcacat tcccaatagt taccatcaga tttttaccat caaatgctag
     2161 attatcaatt ccttgtaaga tctgatctaa tttcacatct cctacatttg ccaaagggaa
     2221 actctttgta actgtacttc caatcgaaat gacaaacgaa gcaagtgata ccaaaccagt
     2281 agaaactgta tcaaccttgt aaatcttagc gatattcact cccaagcaat agatgaacaa
     2341 caaggaaaca attggtatac ttcccttgaa taccaaatta ttgatgtcaa caagccactg
     2401 aaaggttttc gtaatacttt ctaggtgaaa ttgttgtggt aaatccacta gaaaagcatt
     2461 taataacaaa gcaatggaac ctgtcataat aacaggcata gtccccacaa atgaatcacg
     2521 taaagcaact aaaaacttct gattcccaac tttcattgca attggagaaa gtttttcttg
     2581 cattttatcc aacattgtat tcataccaaa ctcctaattt ttttcaaatc gttcgtatac
     2641 ttctaccact tctttcgcca agtcaacaaa agtcagactc gtcattaaat gatcttgcgc
     2701 gtgtaccatc aagaggctaa ttgatgtttt ttccccctgt gcctctcttg tcaacatttc
     2761 tgtttgagcc ttatgcgcct gtaataaggc agcattcgca tcagctaatc ttcgattggc
     2821 tttagagaaa tccccttttt ttgctgcctg aatagcctcc atagcattac ttttggcttc
     2881 cccaccatac ataattagcc ccattacaga ttctaaatta ctttcatcca taacattctc
     2941 ctcaatctta gtctaataaa ctttcagcta aatctaaaac tttagaacca ttcatcattc
     3001 cgtaatctgt catcggaata accgccacag gaatctgtct atcttttagt ttttcttgaa
     3061 agtcccctag taaatagcga acttgaggac ctaaaagcaa cacatttact tcttttgttg
     3121 ctacaatttc ttctgcttca ggagctggaa ctgcaaaaat ttctgcatcc aaccccttat
     3181 cttctgctgc cttttgcatc tttgtcacta gcagacttgt actcatacct gctgcacatg
     3241 ctaacataat tgttacttta gccatagctt actcctttat cacctattta ctgacctagc
     3301 caagcgagat actgtatgtc tcactcctct aattgccttg ctcaatgcat aaatattatc
     3361 gactgttgcc agtcccccat atcctgcgtc acctatatgt tgaatatcaa ctccacaaat
     3421 tttatttcta agtgcaattt ccttgatagt atctgtatca gatgtttctt ggctagtacc
     3481 aatagcactc aatacaagac cacccttact atgaacgaga tcaacgactt cacgcaactc
     3541 ttggtcatga aaggctggaa cggttccaac tgctggaaca agtatcacat ccgcacctgc
     3601 ttccaacaat tgctctgcga cagaaagctc tgccacaggc tcattcactc ctgccccgtg
     3661 cattttacca gctataatca aacctgagaa attctcttta gcagattgaa ctgctttgat
     3721 aatctcttga ttgctaactc ctgttccagg atttccagtc aaacagacaa agtcaaaacc
     3781 taactcctct attcgattca atgtttcaac actagcaaca cgacctgcaa caatttcctg
     3841 tgtttcctct agcatctttg cagatgggtc aatcggttcc aaatttacac caattggaca
     3901 agcaacaagc tggtgtaagc gatgaataac atcatcacct gaactatcca aagcataaat
     3961 tttaggctca aaaacatcaa cacaattcaa taaaatcata tcagctccaa aagctctagc
     4021 aatttcagaa ttagttatat ccccaacaaa tgtctcacga gtaactacat tttcagatag
     4081 aacaactcta ccttcacttg ctaaaatact ttgttttaat tcttcagcat tcatctgtaa
     4141 tatctcagat ggatttgcac taattaaacg tttcattctc aatcctccaa taacttaaac
     4201 cgtttttcaa tagctattac aaatggtaaa taaagtaaga catccaaaac aatcaataca
     4261 atttgtaata atgaaccaga aatacttcct gtagcaagta aaccacttat aacaggtggc
     4321 atagtccaac ctggatctgt ataagttagc ggaaccaaac ctgatgccat tgctccccac
     4381 gctactagta agttaaacat tggagctaag ataaatggaa ctagtaacaa aatgttcaaa
     4441 acaataggaa cgccaaacat tgctggttca tttatattaa ataatccagg tataacagtt
     4501 ataggtgcca aagtttttag ttgtttacta gctttcttct tatgtgctaa atatcctaac
     4561 gcaagaacta aacctatggt tgcaccaccg ccacctatga atacaaaatt atccataaat
     4621 acgctagtaa aaatatttgg aagagtttct ccagtttgat aagctacttt atttgcatct
     4681 agattagcta accataacgg tttcataact gcattaacaa catttcctcc gtgtaatcct
     4741 acaaaccaaa aactactatt aaggaaaatt aagataagaa gaccaataac attatttcct
     4801 aaaagtccaa gtggacctcc caaagctact tgagcaattt catgaagatt aggtaaactt
     4861 aatttatcta aagttgcata aacaatcaac caaccaacaa tagtcactgc accaggaata
     4921 atggcactaa agcttttaga tactgctggt ggaacaccat ccggcatttt tatctgtata
     4981 ttatgattta taaaccattg gtagatatag ccattaatca atcctaaaat catagcaaca
     5041 aataaacctt ttgatgccat gaaagcggta ggcattcctg ctccagcctc tcctctaatg
     5101 aaaggcgtaa ctgtaataaa agatgataat gacacaatac cagcaggaat accatcaact
     5161 ttgtattgtc tagccataaa gtaagcgata ccaaaactag ctacaagacc aagtaatcca
     5221 aaactactat caacaccctt ccataaatag tcagcaacac caatatcacc cagatatttt
     5281 tcccatcctg gaataggaaa acttgcaata accattagta atgaacctat caacaataaa
     5341 ggtatagtta gagtaatacc gtctcgaata gaaaccaacg ctttattatt acccaatcta
     5401 gccgctactg gaagtaactt ttcttgtaat aatttttcca taaccttttc ctcttaaata
     5461 tattttatta tcaaaagtta tcaattatct ttattttttg acgtcaagtt gttatttgat
     5521 tatcttttgt tatttatatt ttacaactat aagaaagcct tgtcaa
//
LOCUS       DAVLCS010000072         5368 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLCS010000072 DAVLCS010000000
VERSION     DAVLCS010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5368
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.072"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            <1..240
                     /locus_tag="VXC78_002006"
     CDS             <1..240
                     /locus_tag="VXC78_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0584007.1"
                     /translation="YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEK
                     QEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            334..405
                     /locus_tag="VXC78_002007"
     tRNA            334..405
                     /locus_tag="VXC78_002007"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:367..369,aa:Glu,seq:ttc)
     gene            658..2203
                     /locus_tag="VXC78_002008"
     rRNA            658..2203
                     /locus_tag="VXC78_002008"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2255..2327
                     /locus_tag="VXC78_002009"
     tRNA            2255..2327
                     /locus_tag="VXC78_002009"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2288..2290,aa:Ala,seq:tgc)
     gene            2452..5353
                     /locus_tag="VXC78_002010"
     rRNA            2452..5353
                     /locus_tag="VXC78_002010"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1557 a         1066 c         1553 g         1192 t
ORIGIN      
        1 tacgataaag aaccctatga agaagtgggt gagatcagtc atcgtataag tgaggggggt
       61 ctctggctag atgattatta tctctttcat gaaacactaa gagattatag aaacaaacaa
      121 agtaaagaga aacaagaaga actagaacgc gtcttaagca atgaacgatt tcgagggcgt
      181 caaagagtat taagagactt acgcattgtg tttaaggagt ttactatccg tacccattag
      241 taagtcatgc aaaaaaaatg aaaaaaatta gaaaaagtag ttgacaaagt ttgaaaagac
      301 tgtataatag taagagttga aaataacaac tcaggtccgt tggtcaaggg gttaagacac
      361 cgccttttca cggcggtaac acgggttcga atcccgtacg gactatggta tgttgcgtca
      421 ggagcacttg atgaaaaaaa gtttaaaaaa gcttaaaaat cttcaaaaaa gtgttgacaa
      481 gtgaaagtgg ctgtgatata ctaatatagt tgtcgcttga gagaagcaag tgacaaagac
      541 ctttgaaaac tgaacaagac gaaccaatgt gcagggcgct acaacgtaag ttgtagtact
      601 gaacaatgaa aaaaacaata aatctgtcag tgacagaaat gagtgagaac tcaaactttt
      661 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta
      721 gaacgctgaa ggaggagctt gcttctctgg atgagttgcg aacgggtgag taacgcgtag
      781 gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc gcataagagt
      841 ggatgttgca tgacatttgc ttaaaaggtg cacttgcatc actaccagat ggacctgcgt
      901 tgtattagct agttggtggg gtaacggctc accaaggcga cgatacatag ccgacctgag
      961 agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga ggcagcagta
     1021 gggaatcttc ggcaatggac ggaagtctga ccgagcaacg ccgcgtgagt gaagaaggtt
     1081 ttcggatcgt aaagctctgt tgtaagagaa gaacgagtgt gagagtggaa agttcacact
     1141 gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc ggtaatacgt
     1201 aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg ttagataagt
     1261 ctgaagttaa aggctgtggc ttaaccatag taggctttgg aaactgttta acttgagtgc
     1321 aagaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat ggaggaacac
     1381 cggtggcgaa agcggctctc tggcttgtaa ctgacgctga ggctcgaaag cgtggggagc
     1441 aaacaggatt agataccctg gtagtccacg ctgtaaacga tgagtgctag gtgttagacc
     1501 ctttccgggg tttagtgccg tagctaacgc attaagcact ccgcctgggg agtacgaccg
     1561 caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc atgtggttta
     1621 attcgaagca acgcgaagaa ccttaccagg tcttgacatc cctctgaccg ctctagagat
     1681 agagttttcc ttcgggacag aggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt
     1741 gagatgttgg gttaagtccc gcaacgagcg caacccctat tgttagttgc catcatttag
     1801 ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat gacgtcaaat
     1861 catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac aacgagtcgc
     1921 aagccggtga cggcaagcta atctcttaaa gccagtctca gttcggattg taggctgcaa
     1981 ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc ggtgaatacg
     2041 ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac ccgaagtcgg
     2101 tgaggtaacc gtaaggagcc agccgcctaa ggtgggatag atgattgggg tgaagtcgta
     2161 acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc tttctaagga taaggaactg
     2221 cgcattggtc ttgtttagtc ttgagaggtc ttgtggggcc ttagctcagc tgggagagcg
     2281 cctgctttgc acgcaggagg tcagcggttc gatcccgcta ggctccattg gtgagagatc
     2341 accaagtaat gcacattgaa aattgaatat ctatatcaaa tagtaacaag aaaataaacc
     2401 gaaaacgctg tagtattaat aagagtttat gactgaaagg tcagaaaata aggttaagtt
     2461 aataagggcg cacggtggat gccttggcac taggagccga cgaaggacgt gacaaacgac
     2521 gatatgcctt gggtagctgt aagtaagcga tgatccaggg atttccgaat gggggaaccc
     2581 aacaggtaat acctgttacc cacatctgtt aaggatgtga ggaggaagac gcagtgaact
     2641 gaaacatcta agtagctgca ggaagagaaa gcaaaagcga ttgccttagt agcggcgagc
     2701 gaaacggcag aagggcaaac cgaagagttt actcttcggg gttgtaggac tgcaatgtgg
     2761 actcaaagat tatagaagaa tgatttggga agatcagcca aagagagtaa tagcctcgta
     2821 tttaaaatag tctttgtacc tagcagtatc ctgagtacgg cgggacacgt gaaatcccgt
     2881 cggaatctgg gaggaccatc tcccaaccct aaatactccc tagtgaccga tagtgaacca
     2941 gtaccgtgag ggaaaggtga aaagcacccc gggaggggag tgaaatagaa cctgaaaccg
     3001 tgtgcctaca acaagttcga gcccgttaat gggtgagagc gtgccttttg tagaatgaac
     3061 cggcgagtta cgttatgatg cgaggttaag ttgaagagac ggagccgtag ggaaaccgag
     3121 tctgaatagg gcgccttagt atcatgacgt agacccgaaa ccatgtgacc tacccatgag
     3181 caggttgaag gtgcggtaag acgcactgga ggaccgaacc agggcacgtt gaaaagtgct
     3241 tggatgactt gtgggtagcg gagaaattcc aaacgaactt ggagatagct ggttctctcc
     3301 gaaatagctt tagggctagc gtcgacatta gagattcttg gaggtagagc actgtttggg
     3361 tgaggggtcc atcccggatt accaatctca gataaactcc gaatgccaat gaattatggt
     3421 cggcagtcag actgcgagtg ctaagatccg tagtcgaaag ggaaacagcc cagaccacca
     3481 gctaaggtcc caaaataatt gttaagtgga aaaggatgtg gggttgcaca gacaactagg
     3541 atgttagctt agaagcagct attcattcaa agagtgcgta atagctcact agtcgagtga
     3601 ccctgcgccg aaaatgtacc ggggctaaaa caatttaccg aagctgtgga tacctttata
     3661 ggtatggtag gagagcgttc tatgtgtgat gaaggtatac cgtgaggagt gctggaacgc
     3721 atagaagtga gaatgccggt atgagtagcg aaagacaggt gagaatcctg tccaccgtaa
     3781 gactaaggtt tccaggggaa ggctcgtccg ccctgggtta gtcgggacct aaggagagac
     3841 cgaaaggtgt atccgatgga caacaggttg atattcctgt actagagtat gtagtgatgg
     3901 agggacgcag taggctaact aaagcagacg attggaagag tctgtctaag cagtgaggtg
     3961 tgaattgagt caaatgctta attctataac attgagctgt gatggggagc gaagtttagt
     4021 agcgaagtta gtgacgtcac actgccaaga aaagcttcta gcgtttaaac atactctacc
     4081 cgtaccgcaa accgacacag gtagtcgagg cgagtagcct caggtgagcg agagaactct
     4141 cgttaaggaa ctcggcaaaa tgaccccgta acttcgggag aaggggtgct gacttaaagt
     4201 cagccgcagt gaataggccc aagcaactgt ttatcaaaaa cacagctctc tgctaaatcg
     4261 taagatgatg tatagggggt gacgcctgcc cggtgctgga aggttaagag gagtgcttag
     4321 cgtaagcgaa ggtatgaatt gaagccccag taaacggcgg ccgtaactat aacggtccta
     4381 aggtagcgaa attccttgtc gggtaagttc cgacccgcac gaaaggcgta atgatttggg
     4441 cactgtctca acgagagact cggtgaaatt ttagtacctg tgaagatgca ggttacccgc
     4501 gacaggacgg aaagacccca tggagcttta ctgcagtttg atattgagtg tctgtaccac
     4561 atgtacagga taggtaggag tctaagagat cgggacgcca gtttcgaagg agacgctgtt
     4621 gggatactac ccttgtgtta tggccactct aacccagata ggtgatccct atcggagaca
     4681 gtgtctgacg ggcagtttga ctggggcggt cgcctcctaa aaggtaacgg aggcgcccaa
     4741 aggttccctc agaatggttg gaaatcattc gcagagtgta aaggtataag ggagcttgac
     4801 tgcgagagct acaactcgag cagggacgaa agtcgggctt agtgatccgg tggttccgta
     4861 tggaagggcc atcgctcaac ggataaaagc taccctgggg ataacaggct tatctccccc
     4921 aagagttcac atcgacgggg aggtttggca cctcgatgtc ggctcgtcgc atcctggggc
     4981 tgtagtcggt cccaagggtt gggctgttcg cccattaaag cggcacgcga gctgggttca
     5041 gaacgtcgtg agacagttcg gtccctatcc gtcgcgggcg taggaaattt gagaggatct
     5101 gctcctagta cgagaggacc agagtggact taccgctggt gtaccagttg tcttgccaaa
     5161 ggcatcgctg ggtagctatg tagggaaggg ataaacgctg aaagcatcta agtgtgaaac
     5221 ccacctcaag atgagatttc ccatgattat atatcagtaa gagccctgag agatgatcag
     5281 gtagataggt tagaagtgga agtgtggcga cacatgtagc ggactaatac taatagctcg
     5341 aggacttatc caaagtaact gagaatat
//
LOCUS       DAVLCS010000073         5342 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLCS010000073 DAVLCS010000000
VERSION     DAVLCS010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5342
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.073"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            692..1564
                     /locus_tag="VXC78_002011"
     CDS             692..1564
                     /locus_tag="VXC78_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV0584008.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(1710..2054)
                     /locus_tag="VXC78_002012"
                     /pseudo
     CDS             complement(1710..2054)
                     /locus_tag="VXC78_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            2197..2508
                     /locus_tag="VXC78_002013"
     CDS             2197..2508
                     /locus_tag="VXC78_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584009.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            2512..3228
                     /locus_tag="VXC78_002014"
     CDS             2512..3228
                     /locus_tag="VXC78_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0584010.1"
                     /translation="MKKYFIGGLGNNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYLTSEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVLDLALLISKEKSGAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(3358..4173)
                     /locus_tag="VXC78_002015"
     CDS             complement(3358..4173)
                     /locus_tag="VXC78_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV0584011.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(4170..5075)
                     /locus_tag="VXC78_002016"
     CDS             complement(4170..5075)
                     /locus_tag="VXC78_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV0584012.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
BASE COUNT         1754 a          931 c         1067 g         1590 t
ORIGIN      
        1 tttacgatac ttcgtttttc tgatcataca gttgcctctc ggcataggtc agaactttac
       61 cttgtctggg tggtgcccgt tggtcgtaga tagattggat atcgctagga gaatcctttt
      121 gaactggagg aaagagggca tcaatcaagc tactgaatac tttaactaag tcaaatatag
      181 tatttttctt agtagaccta accctttttt cataatttct aatggtgttt ttacttatac
      241 ctatcttagt acccaattct tattgagtcc aaccattact agtctatatt gttttatagt
      301 tgattgagtt tggaatagta cgctgtagct gctaaaacat ttctaggaat taatttgcct
      361 ttcctaatag agttgttcat atcttatttc aatctactat atttttcacc tctaacaatc
      421 gcaatctctt ctttatccat gaacgaaaac gctttctatc tttgtaagta aagcatcaca
      481 cgaaatccac gaaaatgaaa acctttgttg tgttttcgta aaaaatttgt tgacagagca
      541 cgaaacgcct actataatta aatcaagttt aaggaaataa caaaaaaaca aatcggaggg
      601 aaagacgatg aacacattaa atgagaaagt aatcaatatc tgtaaagcag tagttaaaga
      661 aactttaatc caagacattt aggagaaaga aatgaagaaa tcaagaaaat tagccacatt
      721 aggaatctgt tcagccttgt ttttaggctt ggctgcttgt caacaacaac atgctacttc
      781 tgaggggacg aatcaaaggc aaagcagttc agcgaaagtt ccatggaaag cttcatacac
      841 caacctaaac aaccaggtaa gtacagaaga ggtcaaatct ctcttatcag ctcacttgga
      901 tccaaatagt gttgatgcat tttttaatct cgttaatgac tataatacca ttgtcggctc
      961 aactggctta tcaggagatt tcacttcctt tactcacacc gaatacgatg ttgagaaaat
     1021 cagtcatctc tggaatcaaa agaagggcga tttcgttggg accaactgcc gtatcaatag
     1081 ttattgtctt ttgaaaaatt cagtcaccat tccaaagctt gaaaagaatg accagttgct
     1141 tttcctagat aatgatgcga ttgataaagg aaaggtcttt gattcacaag ataaggaaga
     1201 gtttgatatt ctattttcga gagttccaac tgaggcaact acagatgtca aggttcacgc
     1261 tgaaaagatg gaaacattct tctcacaatt tcaattcaat gaaaaagctc gaatgctgtc
     1321 tgtagtcttg cacgacaatc tggatggcga gtatctgttt gtaggccacg ttggggtctt
     1381 agtacctgct gatgacggtt tcttatttgt agagaaattg actttcgaag agccctacca
     1441 agcgattaaa tttgctagta aggaagattg ctacaagtat ttaggcacca agtatgcgga
     1501 ttatacaggc gagggactgg ctaagccttt tatcatggat aatgataagt gggttaaact
     1561 ttaatagtgt tatgatatga cagtaatctt aggattttta tttctatttt tgatgagttg
     1621 gtgggttatt tcaatcgtta atagccagaa accacgcaaa aatgaaacat ttattggcta
     1681 tatccaaaga tacgatattg atgggaatgg ctatcaatca ttaccgtgtc ctcagaactg
     1741 agaggagttc ttgaaatcgt aaaactactt tgaacaagag ttacttcaac ccattggctc
     1801 cgacggatta agttgctttc gtgaacacca aaatcagccg caatttcttc ataagtgcgg
     1861 tattctcgca catattgaag agtggccata agaaggtctt ctaggcttaa tttaggtttt
     1921 cgtccccctt ttgtgtgttt aagttgataa gcagttttta atacagctaa catctcttca
     1981 aaagtggtgc gctgaacacc aacaagacat ttaaatcgtg catcagttag ttgcttactt
     2041 gcttcataat tcatagaact actataccat attttgtttc gcaggaagtc taatgctaaa
     2101 atcttatcag tgagaagatt tcttaaagtt tattctttgt agtttcatct gtattagtac
     2161 ataatttaac ttagagaaaa taggaggact aatcgaatgg aattaaaaga ttttacagaa
     2221 aaagaacagg aaatgattaa gaaaaggctt acaatgtcta atattagtga caaagaaact
     2281 actgagaaga ttctggcgct agtaccacaa gacttgatta agcgaatccc gttttttgtc
     2341 agaaaacatg ctacaacacg tacgattaaa cgcatttcaa ttgaacaccc tgaactctac
     2401 gctgtagctc aaacaagtgg tgagattcca gaaaaagaac gcgaagaatt gcgtcagatt
     2461 atcacaacta tctttgaaca aaagatgaat aagcatagta ttaagtagag aatgaaaaaa
     2521 tattttattg gcggtttggg aaataatgcc tatcatagca aggattttct tcaagaacta
     2581 gattcgcagg tctattttct aaatccatat gaaaagcatc ttcgagatga aacagaattg
     2641 aaatcatggt ttaaaaatga gattgtagag gaagaatcta tctgtctgat aggccattct
     2701 cttggaggag atttagctcg ttatctcaca tcggaatttg aagaagtaaa aaaactgatt
     2761 cttttggatg gtggctatct agatttagat aagattttac ctttggatac agagttagag
     2821 gaaactaaaa attatatcaa atctcaaatt gttttggact tagctcttct tatttctaaa
     2881 gaaaaatctg gagcaaagca ttggtcagaa aatatggaga aagctgtaag acagtcttat
     2941 cactggaatg ttgagtataa tagatatgag ttggctataa attatgaaaa tatagaagcg
     3001 atactccgcc tacggagaaa aatacaagct tttaagagag aagtgggaga taccttgttt
     3061 attagtcctc gctatcctaa tgaagctaca tggagagagg aagccctaaa agaattgcca
     3121 gactattttg atactatttt tttagaaaac tttggccatg agctttatac tcaagcacct
     3181 aaagaaatcg ctagtctaat gaatgagtgg ctcgcttatt ttctatgagc tacttgtatt
     3241 gctggaaatg gtataagatg aaaatctaca agtcactaat tttcatataa ccaaaaaacg
     3301 aacaggctct ttttctgtta ttcagaagag aacttgttcg tttttatctt gattttctta
     3361 aaaagctcta tatacatagg gattttctgg tttatcgact ttggtaaagc tgtcgatttc
     3421 caaggttgga aggttttgtt tgagttcttt atggtagtga ttgaccagtt ttcctttggc
     3481 tgaaatccaa gtgttgtttt catactgccg ggtattgccc ttggtcagca atccatagac
     3541 accagaatct gcgatacagt ggataatgcc gaatcggaac agaaattgac tattggcatg
     3601 actggggtcg ttatagacaa agcctgtaaa ctggattgtc ttgccctcaa actcatctgg
     3661 atagtcgtag atagcctcca tgacttccat atagttttca ttagtgatct gaatactatc
     3721 ttgggataag tatttatccg ccgccgttcg catttccttt tcataggctg attttgaaaa
     3781 ataagaactg gtatctggtt tcaaatattg gcttgtcgtc ccttcgcttg tctgaatggc
     3841 tagatccgtt ccttccgata gggggaaatg ataaccttta gcagaaacag tctgagaatc
     3901 caagctaaca gttgggaaag ttaagccaat gacaagtgga atagctagaa gagaaatact
     3961 cgtcatcttg gccaatcggc tgttcagatg actgtgggtt ttgacttgct tcatccagat
     4021 atacaattga acaatagcca agataaagga aagcaccatg gaaatatagg ccagatagga
     4081 atagtgcatg ttgatgtact ggtttagttt gcccgacaga tggaggtaaa tagtcagttc
     4141 aaaatagcca gctaaaacta aaaatcgaat cataggatga ctccaatcaa gagagaatag
     4201 gctaaaacga ccagagtcac aatcgtaatg aagtgactaa taaatcgtgc tttcaagtaa
     4261 tttttcatca tgagaatatt tttgatatcc agcattgggc caatgacgag aaaggccaga
     4321 actggagcca aaccgaaact cgagagtaga gaagcaccta taaaggcatc cgcctcacta
     4381 cagagcgaaa gaagaaaggc caaaagcatc aagagcagga tggcaaaaag aggagtcgca
     4441 ctgatagagg tcagaatccg agtcggaacg tagacctgta ttatagaagc aaagaggcag
     4501 ccaaatacca aataacgccc cgtatcaaaa aattcatcaa tggcctgcac aaagacttga
     4561 aaaacttttt ttgcagaact caagtaagaa aaatcatgct catgacaagc cagacgattt
     4621 tctttctgaa tcggttcttg ccagaaaaat cctagaaaaa ttcctagtat tacagccaca
     4681 agaatggaac ccagagctcg taatagggcg acatggaagg agttgccaaa ggcagaatag
     4741 gtcgcaaaaa gaacaatggg attgataaca ggtgctgtca caagaaaagg aacggccgtg
     4801 taacttggaa cctttttttc cagaaaacga ttgatgatgg ggacgattcc acattcacaa
     4861 gaagggaaaa gtataccgac aaaggtccca aaaaagattc tcccccaacg atttcgaggg
     4921 agaaaatgat aaaccttgtc aggtgtgata taaacttcaa tcagccctga gacaatgctt
     4981 cctatcagaa cgaagggaag ggcttcaatg ataatggaga gaaaaatggc tccagtttga
     5041 agtacactag atgggagttg ttgaaaagca gtcatctagt ttttcttttc tgctttgact
     5101 tttttctctt tgtcatcagg gaaagtaact tgtttcaaat cagggagttt agcaaactct
     5161 tcaaacatct tgtccaagtc gtctcgtttt gtaaatttga cagccatagg tgtacctcga
     5221 ttctaaattc tacctctatt atactattat tttgcggaaa agggagtttt ttaatttgtt
     5281 ttcgatagtt gatacacttc gaaaatctct tcaaactacg tcagcttcgc cttaccgtag
     5341 ta
//
LOCUS       DAVLCS010000074         5299 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLCS010000074 DAVLCS010000000
VERSION     DAVLCS010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5299
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.074"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            93..859
                     /locus_tag="VXC78_002017"
                     /pseudo
     CDS             93..859
                     /locus_tag="VXC78_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850213.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1678..2037
                     /locus_tag="VXC78_002018"
     CDS             1678..2037
                     /locus_tag="VXC78_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584013.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            2047..2412
                     /locus_tag="VXC78_002019"
     CDS             2047..2412
                     /locus_tag="VXC78_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV0584014.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYEQLVFELRRIGNNINQIARAINQSHLISQNQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSY"
     gene            2399..4264
                     /locus_tag="VXC78_002020"
     CDS             2399..4264
                     /locus_tag="VXC78_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV0584015.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSHAEMVEMYNVNFSNNDKLYESRNDRQEKHQQTIHAHYLIQSFSPEDNLTPEEINR
                     IGYEIMMELTGGRFKFIVATHTDKDHVHNHILINAIDRNSDKKLIWNYALERNLRMIS
                     DRISKVTGAKIIEKRYSYRDYKKYRESSHKFELKQRLYFLLQQSKSFDDFLEKAKQLH
                     VQIDFSQKHSRFLMTDRTMIKPIRGRQLSKRDLYDEDFFKIYFAKQEIESRLKFLLKS
                     VYSLEELHVKAKELNLTIELKQKNVMFTLEEDGKKISLSHKKISDKKLYDVQFFNRYF
                     EDREVRDIQALENLQEDFQTFREEQHKEKVSAEEIEEAFKKYKEKRDAIHEFEIELTD
                     NQIEKLVDDGVYIQVSFGIKQSGLIFIPNYQLDIFEEDNHKKYKVYIRETSSYFVYNK
                     ENMDNNCFIKGRTLIRQLSNDSQKLPYRRPTLKSLKEKISEINLMIELSNTNKQYQEI
                     KDELVLEIAEIDMQLEETQEKIATLNKMAEVLINLKSEDHETRKLAKYDFDQMNMTES
                     IMLDRLNTDILKLQQELGNEINKYEEIARRLDLFVKIINTNKFTVLKFHENALLE"
     gene            complement(4309..5163)
                     /locus_tag="VXC78_002021"
     CDS             complement(4309..5163)
                     /locus_tag="VXC78_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0584016.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLVLHNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKVEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIDKEEFSNCSYLISKIK
                     TLLDNELNFYEQTVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGEDKLKLHYTDH
                     FNKLVNKK"
     gene            5243..>5299
                     /locus_tag="VXC78_002022"
     CDS             5243..>5299
                     /locus_tag="VXC78_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HEV0584017.1"
                     /translation="MKKISKFLPILVLVMDIII"
BASE COUNT         1911 a          773 c         1000 g         1615 t
ORIGIN      
        1 caatcataaa aaatggaata gaaatagttg tagtaactga tcataatact accaaaggta
       61 ttaaaaagtt acaaatggca gtctcaatca taatgaaaaa ttatccgatt tatgatatac
      121 atcctcatat tttacatgga gtagaaatta gtgcagcaga taaattgcat attgtatgta
      181 tatatgatta tgaacaagaa tcatgggtta atcaatggtt aagtgaaaat attataagtg
      241 agaaagatgg aagttatcaa cattcactga ctataatgaa ggatttcaat aatcaaaaaa
      301 tagttaacta tattgctcat ttcaatagtt atgacatttt gaaaaaaggt tctcacttat
      361 caggtgcata taaacgaaaa attttttcta aagaaaatac acgattttgg agtttaatat
      421 taactcgaaa gaatcttcgc aacaacttga tattctctat aaagaagttg gtgtattaag
      481 tttgggacaa aaagttgtag ccatgcttga ttttttatta gcatatagtg attattctaa
      541 agacttcaga ccattgatta ttgatcagcc tgaagacaat ctagacaatc gttatatttg
      601 caggcattta gttcagcagt ttagagatgt gaaagctcaa cgtcaaatta ttttagcaac
      661 acataatgct acaattgtaa caaattctat gacagatcaa gttgttatta tggagtcaga
      721 tggagttaac ggatggattg aatcacaggg atatgttagt gaaaaatata taaaaaatca
      781 tatcatcaat caattagagg gaggaaaaga ttccttcaag cataaaatgt ctatatatga
      841 gacggcttta tcagagtaga gtcagaaaaa gtaggttaga aatttagcct acttttttct
      901 ttgtccgaca ggcatagtgt gcatctgagg tccaagtcct ctgtggatat ttgctgcaga
      961 tgaaaccaat agcgactcct aagcctgaat atcgtgaggt aggggggata ggaaggaatt
     1021 agcgaaatca aggttctaca aacagaatcg tgacttgaag ccatatatag cggatgagga
     1081 actctaaaat ccaaataggt gtcgtaacct atatacgtaa attacgagag taaactagga
     1141 aagatgtacg gcttattccg tgagcgttta ggacgtagta caacgaatca tgggagtcag
     1201 ctgaacacat agtattgaag aaatttctgt aatggaaatg gagcgaagaa gtgaacaatt
     1261 aaatgaatac ctctctaatt aaatttgtca attctaattc ctggtatgaa aagacagtga
     1321 cctgaaaatg taaacgatgg gagctgatta taaatatagg acggtacatg cagtggtgtt
     1381 agagattagt ccctacttga tttgtgataa cttccccaaa tttcttctgc tatacttttc
     1441 tcaactttta aaaatccaac taagaatttt acctgggggt ttgggggcga agccaccaag
     1501 ttatcttatc gttggctgtc aaaactggaa ggttttggtt agctggcgat atgatttttt
     1561 gggtattgta accacaatgc ttgagctcgc aaagaccgaa caaggacttt aagaaatttc
     1621 ccgtatgaca cacggggtcg gggtttaccc gagaaaggat gaaagtgagg aaaagagatg
     1681 tctgaacagt accgtgacat tcgaaaagag gtaaatctaa ccgcagatga gctaaaacag
     1741 attgaaaaaa tgatggaggt tgataattat cgtcactttt caccattcgt cagggataaa
     1801 attttgatga ctgatgacaa acagttagct gccaaagaat ggttttccct ttggcagtct
     1861 caaaagtttg aacagatcag tcgagatgtg catttggttt tgattatcgc aagagagaat
     1921 caccaagtga ctcaagaaca cgtgtcaatc ttattgacct gcgttcaaga attgattgcg
     1981 gaagtcaatc aagtacagtc actcagtcgt gggtttcgtg aaaaatacat gagataggag
     2041 gctactatgg tttatcgtta tcgtaccaat ctcaaaaaag tatttctaac agattcagaa
     2101 ttacaccaat tgaatgaacg gattgctaag agcaattgtc aaaatttctc agtctatgcc
     2161 agaaaagttt tgcttaatcc caatatgtca tttgtcacga ttaacactga tacttatgaa
     2221 cagttagtgt ttgaattgag gaggattgga aataacatca atcaaattgc gcgtgcgatt
     2281 aatcaaagcc atctgatttc tcagaaccaa ttacaagaat tgagtaaagg agtcggagag
     2341 ttaattaagg aagtggacaa agaatttcaa gtggaggtga aaagactgaa ggagtttcat
     2401 ggtagttact aaacactttg cgacgcacgg aaaaaaatat cgtaggcgtt taattaagta
     2461 tattctcaac cctgataaaa cggacaattt gaaattggta tctgattttg gcatgagcaa
     2521 ttacttggac ttccctagtc atgcagaaat ggtagagatg tacaatgtca acttcagcaa
     2581 taatgacaag ttgtacgaat ccagaaacga ccgacaagaa aaacaccaac aaactattca
     2641 tgctcattac ctcattcaat cattttctcc tgaagataat ctgacacctg aagaaattaa
     2701 ccgcattggt tatgagatca tgatggaatt gacaggaggt cgttttaagt ttatcgtagc
     2761 aactcacaca gacaaagatc atgttcataa tcacatccta atcaacgcta ttgaccgcaa
     2821 ttcagataaa aagttgatat ggaactatgc cttggaacga aacctccgta tgatttcaga
     2881 ccgtatttct aaagtgactg gtgcaaaaat tattgagaaa cgttattcct atcgagatta
     2941 taaaaaatat agggaatcta gtcataagtt tgaattgaaa caacgtcttt attttttgct
     3001 acagcaatct aaatcgtttg atgatttttt agagaaagca aagcagttgc atgttcagat
     3061 tgattttagt caaaagcata gccgtttttt gatgacagat agaacgatga taaaaccaat
     3121 tcgaggacgc caactcagca aacgagattt atatgatgaa gactttttta aaatatattt
     3181 tgccaaacaa gagattgaaa gtcgtttaaa atttttacta aagtctgttt attcattaga
     3241 agaattgcat gtaaaggcta aagagttgaa tctaaccatc gagttaaaac agaaaaatgt
     3301 gatgtttacc ctagaagaag atggcaaaaa gataagcctg agtcataaaa aaattagcga
     3361 taagaaattg tacgatgttc aattttttaa tcgttatttt gaagatagag aagttagaga
     3421 tattcaagca ttagaaaatc ttcaggaaga ttttcagact tttcgagagg agcagcataa
     3481 ggagaaagtc tccgctgaag aaatcgagga agccttcaag aaatacaagg aaaaacgaga
     3541 tgctatccat gagtttgaga ttgaacttac ggataatcag atagagaagt tggttgatga
     3601 tggtgtctat atacaggttt cgtttggtat caaacagagt ggactcatct ttattcctaa
     3661 ctaccagcta gatatttttg aggaagacaa tcataaaaaa tataaagtct acattcgaga
     3721 aacgtcttct tactttgtct ataataaaga aaacatggat aataattgtt tcatcaaggg
     3781 taggacctta atcagacaat tgagcaacga tagccaaaaa ctcccctata gacgaccaac
     3841 tttaaaaagt cttaaagaga agatttctga aattaatctt atgattgaac tatctaacac
     3901 gaacaaacaa taccaagaaa tcaaagatga gcttgtatta gaaattgcag agattgatat
     3961 gcagctagaa gaaacccaag aaaaaatcgc caccttaaac aagatggcgg aagtccttat
     4021 caatttgaag agtgaagatc atgagactag aaaattagct aagtatgatt ttgaccaaat
     4081 gaacatgacg gaatcaataa tgttagatcg actcaatacg gatattttaa aattacaaca
     4141 ggaacttggt aatgaaatta ataaatatga ggagatagct agaagattgg atttgtttgt
     4201 gaaaattatt aataccaata aatttacagt tctaaaattt cacgagaatg ccttactaga
     4261 ataatattat ttacgactaa ttagttaaaa gatagagaat aatttcattt attttttatt
     4321 tactagttta ttaaaatggt cagtatagtg taattttaac ttatcttctc ctaaaatatc
     4381 gaagacttgt atggcttgtt tcattttttc aattccactg gttgattggc aacgtttaaa
     4441 ttcaaagtaa ccagttgcat agagaaaaac tgtttgttca taaaagttta gttcattgtc
     4501 caacaatgtc tttatcttac taattaaata ggagcaatta gaaaattctt ccttatcaat
     4561 gcttagaatg aagcaattaa tagcaagctg agagacaatc tgcttattag ttttattcag
     4621 agatgagtaa atatagttat ttaacatctc tttagttaat aagaagtagg agttgtagtt
     4681 aattgtgcgt acacagttac ctaataaaat gatttcataa tagccccatt tttcaacttt
     4741 gaaaagatag tctgtcagat gaagaagctc ttcatctgat ggaatgatgt tcgaatccat
     4801 tgtgtgtaaa atagatttta ccattgtttt ctcaaaagaa tttagagtgt aatcagaagt
     4861 atcagaaagt agacatgcta tattattgat actttgtgat gaatattgct tacgaatgta
     4921 ctgtactaga ttagcaaatg attcggaact ggtatagtcg tcattgtgta aaacaaggaa
     4981 ctcatccaaa gtaatatgta atttgtctaa aatattgatt agtcgaatac aagatatctc
     5041 tgactcccca cgttcaaaac gagatatttg tgattttgaa agatgttcat ctgctacaga
     5101 gcatagacta atttgttttc ctttacgaac ttttctaagt gtgatgccaa gttttgattt
     5161 cataatttcc cattttccca acaaaaatta aatccgtttt tatttattgt acaataaata
     5221 aaaacggaaa ggaagtccaa gtatgaagaa aatttcaaaa tttttaccga ttttggtttt
     5281 ggtgatggat attatcatc
//
LOCUS       DAVLCS010000075         4930 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLCS010000075 DAVLCS010000000
VERSION     DAVLCS010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4930
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.075"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(<1..251)
                     /locus_tag="VXC78_002023"
     CDS             complement(<1..251)
                     /locus_tag="VXC78_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584018.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESF"
     gene            complement(248..601)
                     /locus_tag="VXC78_002024"
     CDS             complement(248..601)
                     /locus_tag="VXC78_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0584019.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSPGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLAGAAGRIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            1360..1680
                     /locus_tag="VXC78_002025"
     CDS             1360..1680
                     /locus_tag="VXC78_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0584020.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(1732..2319)
                     /locus_tag="VXC78_002026"
     CDS             complement(1732..2319)
                     /locus_tag="VXC78_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0584021.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            2561..3232
                     /gene="sdaAB"
                     /locus_tag="VXC78_002027"
     CDS             2561..3232
                     /gene="sdaAB"
                     /locus_tag="VXC78_002027"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV0584022.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            3241..4113
                     /gene="sdaAA"
                     /locus_tag="VXC78_002028"
     CDS             3241..4113
                     /gene="sdaAA"
                     /locus_tag="VXC78_002028"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV0584023.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            4135..4767
                     /locus_tag="VXC78_002029"
     CDS             4135..4767
                     /locus_tag="VXC78_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0584024.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
BASE COUNT         1513 a         1041 c          887 g         1489 t
ORIGIN      
        1 aaaaaacttt ctgggaaaaa cttattgatt aaaatgggga aactcattaa cagaatcgaa
       61 tttatggcta gacagataga tactatttta tttttcacag aatatagagg tagtgatact
      121 attgagtaga taaaagctaa aaaaataagc aaaaaatact ccgtgtcatt tataatcgcc
      181 ctgaatgata aaaatatata catccaacat acgataatgt gtatttttcg aatcttatct
      241 acattactca tcttactgtc gcagatatga atccatccca aggataaggg ttcccgctaa
      301 tatcacaacc tctattaaga gcaccatatc caatacagta agctattctt cctgccgccc
      361 cagccaatac acctgctgct gcaccaataa gccaacctcc aaggcctcca actttaatat
      421 agtttattag ttttttggtt aaaactgcag ctccagctaa tgctataaaa gttcctggac
      481 tcatagctaa agctgcgcaa attccttgac aagcacgctt gcttaaataa gctcccccat
      541 caaggtacat catctcttct tcatcaatca caacataatt atttggtaat acaagttcca
      601 tttgttttct ccttttttat taagcatggt taggatggtt tcctaacaag tgatcgcagg
      661 ctttgtttag ttacctaaat tagacttcct ttctttatct tattttaaat atttaaaacc
      721 agttactgct tgaagcttaa cagtttactt aattcaaata acagctaatc actgattccc
      781 tgattttatc aaatatacta ataacaacaa ttgtgatacg atcatcatta taagaacaac
      841 atttaacgaa tcaaagtttt tccgagataa taataaagca acagcaagca gtattattac
      901 taaagattga ataactacta ttactcttaa cattttatcc tccactaaca actcaagctc
      961 ccttacatta tatcgaccag ccccatggaa agattatagc tagactaatc aatgatataa
     1021 tacatactag aatacaaaat atttttttat tcatactttt tctcctatct ttattttcta
     1081 cctacatagt acctcttatt aagctcattt caaaattacg ttaacttttt tcacgaaaag
     1141 gagaaaatta tgcgttatga ttatggatag cgctttcaaa tttttaaact cttatcccat
     1201 ccttttatct atataataag tgaaaatata ataactgtca agtaatcgaa gtgaatttta
     1261 taaaaaaaat tacaagccaa atttgcaaag tttacaataa gccgctaggg caatcgtcta
     1321 tcagaatgtc cgtttatttg tcaataatcc gagaaaatct tgcaacgctt agaagtctat
     1381 aaaaactatc aacatttata tgacttgcga atagcaatcc tgctcaacct ttccacacta
     1441 tatctataca atcaagataa aaacatgtgt aagcaaatct gctacacttt actggaggac
     1501 gccaagaata agaaaagcta cgataggctg gctatctgct atgtccgcat tgggatttgt
     1561 acagacgatt ctaaacttat ccaaaaaggt ttctcactcc tagagctgac cgaggaaact
     1621 tctatgctgt ctcatctcaa aaaagaagta gagatctatt accaagcgaa ggaaagataa
     1681 aaaagccgag ggatttcctc gactctttac atattatttg ttcgttagtt cttaatacca
     1741 gccattgtta agccagaagt ttttagcagc agtccatgaa ccgtaacgtc ctgcaacgta
     1801 ggcatctgct acacgttctt ggttttcagc tgagtagtca ccgttcaggt atgaatctgt
     1861 taattggtaa cgtccgatat aacgtccatt tgtagctgta tagctaccac ctgattcttt
     1921 ttgagcgatc cattctttgg cttctgcttc agatccgctt acagttgaaa caactgtttc
     1981 acttactact ggagtttctg ctactggagc tgaaacagtt tcatcttgag cggctggtgc
     2041 cgcataagta gctggcgctg gtgttgcaac aggcgctaca gggccatcga taaccaactc
     2101 ttgatcaaca taaatcaaat gaatgttatc aatgtggttg ttttctgcca atttttcaac
     2161 tgttgtgttg tgagtttcag cgatttctga aagtgtatca ccttctttaa cagtgtaagt
     2221 tgatgattct tgagcagata caaatgatgg agcaaatact gcaaacaagg cagctactcc
     2281 tgcaagagtt gctttaatct ttttagttat tgatttcata ttcgaaaatt ctccttcttt
     2341 ctatagttct atcataccct ttaaatatta ccgtttcttg acacttttat gtagaaatat
     2401 tacaaaatta ttttttattt ccctaaataa ggtgtttttt gtcataaaag atactatttt
     2461 tatgctattt gaggtattag aaaggttttc atccacaatt aaagccaagc ccctcattct
     2521 ttgatataat agagataaga atttttataa ggggaaactg atgaaatcac ttcgttttca
     2581 atctgtcttt gatatcatcg gaccagttat gattggccca tctagtagcc ataccgctgg
     2641 tgctgttcgt attgggaaga ttgtctcttc catttttgat gatactccga cagaagttga
     2701 attccaactt tttaactcat ttgccaagac ctatcgtggt cacggaacag acctagccct
     2761 tgttgcaggt attttaggaa tggatacaga tgatcctgaa attccaaata gtctggaaat
     2821 tgcccacaag cgtggtatca agattgtctg gaccattcag aaagacagca atgcccctca
     2881 ccctaacacc actaaaatta ctgttaaaaa tgcccacaag accatcagcg tgactggtat
     2941 ttctatcggt ggaggaaata ttcaagtaac cgaactcaat ggttttgccg tctctctcaa
     3001 tatgaataca ccgactatca tcatcgttca tcaagatatt ccaggtatga ttgcccttgt
     3061 tacagaggcg ctttcccgct atggtatcaa tatcgcccag atgaatgtca ctcgtgaaaa
     3121 agctggtgaa aaagccatta tgattatcga agttgacagt cgcaactgtg atgaggctat
     3181 cgaagaaatt cgaaaaatcc ctcatctcca caatgtcaat ttctttaaat aggaggaagc
     3241 atgttttatt ctatcaaaga attggtcgag caagcagatc tggactttca aggaaatgtc
     3301 gcagaactca tgattacaac agagtttgaa ttgaccggtc gcgaacgtga agaagtcttc
     3361 cttctcatgg aacgcaatct ggaagttatg aaagcctctg tccaacttgg cctcaatgaa
     3421 aataaatctc gtagtggcct gacaggtgga gatgctgcca aattggatca ctacatcgaa
     3481 aacggaaaaa ctctgtcaga ttatacgatt ctctcggctg cccgaaatgc catcgcagtc
     3541 aatgaacaca atgccaaaat gggcttggtc tgtgccactc caaccgctgg aagtgctggc
     3601 tgtctgccat ccgttctcac tgctgctatt gaaaaattag acctcagcca cgagcaacaa
     3661 ttggatttcc tctttgctgc tggtgccttt ggactagtca tcgcaaacaa tgcctccatc
     3721 tcaggtgctg agggtgggtg tcaagctgaa gttggttcag cctctgctat gagtgctgcc
     3781 gccttgactc tggctgcagg tggaacacct tatcaggcca gtcaagctat tgcctttgtc
     3841 attaaaaata tgctaggcct catctgtgac cctgttgcag gtttggtcga agttccctgt
     3901 gtcaaacgta atgccatggg agctagcttt gctttcatcg cagcagacat ggccttggca
     3961 ggtatcgaat ctaaaatccc tgtggatgaa gtgatcgatg ccatgtacca agtaggagca
     4021 agcatgccaa ctgcctttcg tgaaacagct gaaggtggac tcgctaccac ccctactggt
     4081 cgtcgcctcc aaaaagaaat tttcggagaa taagcttatc aaataggaga aaccatgacc
     4141 tctatcacag cgattttttt cgatttggat ggaaccctcg ttgatagttc tatcgggatt
     4201 cacaatgcct ttacctatac ctttaaagag ctgggggtgc ctagccctga tgccaaaact
     4261 attcgtggtt ttatgggacc acctctcgaa agtagttttg cgacctgcct gtccaaagac
     4321 caaatttctg aagccgtgca gatatatcgt tcttactata aggcaaaagg catctatgaa
     4381 gctcaactct ttcctcagat tatagacttg cttgaggagt tatcgagcag ttatccactc
     4441 tacatcacca cgacaaagga tacatctact gctcaagaca tggccaaaaa cttggaaatc
     4501 catcatttct ttgatggcat ttatggttct agccctgaag caccccataa ggcagatgtc
     4561 attcaccaag ccttgcagac acatcaacta gcaccagaac aagccatcat catcggagat
     4621 accaagtttg atatgctggg agctcgagaa acaggtattc agaaattggc catcacttgg
     4681 ggatttggag agcaagcaga tctactaaac tatcaacctg attatatcgc tcacaaaccc
     4741 ttagaagttt tggcgtattt tcaatagcat agactgggta acaattccat ttcagaagaa
     4801 aatgaagtaa tactcaatga aaatcaaaga gcaaactagg aaactagctg cgggctgctc
     4861 aaaacactgt tttgaggttg cagatagaac tgacgaagtc agctcaaaac actgttttaa
     4921 ggttgtggat
//
LOCUS       DAVLCS010000076         4893 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLCS010000076 DAVLCS010000000
VERSION     DAVLCS010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4893
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.076"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            78..605
                     /locus_tag="VXC78_002030"
     CDS             78..605
                     /locus_tag="VXC78_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584025.1"
                     /translation="MIKYKELKSYIDEWRYYSDENNPRLDLEYCKTKIVEKAKEFDLP
                     CQIDEEQIKLGGLFNKEIEECLVISHPNHQKDYVKFCFRLKNQGSVQLLTIDTLGESK
                     QLKKYYISEDNKRFREAIRESDLSLGQKLGAQLSNLTVSGLRTLGKNQSKIDAELQYC
                     EFLTEVLTQFRSNND"
     gene            615..2153
                     /locus_tag="VXC78_002031"
     CDS             615..2153
                     /locus_tag="VXC78_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp70 family protein"
                     /protein_id="HEV0584026.1"
                     /translation="MSKAIGIDLGTTYSAVSVLSETGQPQILLNQDGENLTPSVVFFQ
                     DFDGKDEPLVGIQAKNLAASRPEAVVQYVKRQMGNPNWKFDSPSDTVYTAEEISAIIL
                     KRLKEGAENALGDKVEDVVITVPAYFDDARRTATKHAGEIAGLNVLRVLNEPTAAALA
                     YGISAEKNETVLVYDLGGGTFDVTLMKIKDGEFDVIATDGDRNLGGFDFDNALSMIIA
                     EKMEEQGAEDIYTDEHFTALLREKSENTKRGLTTVEKTNVFLDYKGKSYKIPITRVEF
                     EEATKSLMNRTEELLDDVVEESGMSWDEIDQVLLIGGSTRMPMVQRKLEEKIGKKIVY
                     SINPDEAVAQGAAIQAALEIANKSESADVSETVRGLAEKLVVSDVTSQALGTLALSNG
                     VKRNTIIIPKNSKVPNKYSEYFSTVVDNQQNVLVEVTQGDDEDPQFVTVIGESTIKLP
                     GDWPAGTVLKVTYHYDVDQTVFVEVHDSDNHLLGTFEVERQANLDKSAVEVASRKIKD
                     LTID"
     gene            2166..3533
                     /locus_tag="VXC78_002032"
     CDS             2166..3533
                     /locus_tag="VXC78_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV0584027.1"
                     /translation="MSVINYYEELGISETSSLDDVKKSIKSNRRRYRQLTGSPNIDQR
                     SMAERKMEVIAQAEKVFESEETRQKYDRELENSKQSSEGVPDSTPTNHSNSSYLDSAR
                     QAFYSGKKSLAYSYIEEALKINRNDADVWYFKAMISLEDRKLSDAELAISEANRLRPK
                     NADILSLLGDVYCEQNQQKFAIQYYQEAFELSNNSFYLLKKGRSLFLFDQYKQAVKDV
                     RYLYDHYLEENKNNEEYIYYLLSCSYREIGDNEEAYNFARKLVDVSDSLEHKLHYAGI
                     LFLKSEDECENYLDTLNERYGNNKDFQQVYFKLLLDITIERMKKAPDTDVEAFFRKYI
                     DRTKYENEAVLDNKARVRIAEAYLAKAQSLGIENKIIDNDFYNEFIENKNYINYATTR
                     HSQGMGCLMFILVFAANWFLSGFFDKFVHSFWISNALSLALLSNIVLYYNYPKGWQIN
                     RRKKG"
     gene            3541..3999
                     /gene="grpE"
                     /locus_tag="VXC78_002033"
     CDS             3541..3999
                     /gene="grpE"
                     /locus_tag="VXC78_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV0584028.1"
                     /translation="MSEEVLHEKVSYIVDKVEDIESLITRRLLEDKAKNSLIEELKQY
                     LIYRQDLDKGEKFAPFMKQILQVIDRIESSEEKSDLLTSIAEELLQILSLNGLQVIDN
                     SGMIDPSMHEVVNTVAVTDEQSENNIVEVLQKGYLLNNRVLRPSKVTIAK"
     gene            4024..4836
                     /locus_tag="VXC78_002034"
     CDS             4024..4836
                     /locus_tag="VXC78_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NERD domain-containing protein"
                     /protein_id="HEV0584029.1"
                     /translation="MLRFFKHRRNILYFILGFLWGRRQNAKVSPEPPTPSTPKHSELP
                     SISKATHNGKMTGFEPQKLKTYQLYQHELMFGEPGKGLNKSGFDESAVNLGQEGEINF
                     AKALQKKGLLEKLVTFWSVHNLNLEDERVDADIDCVIVSGSTIWLVDLKFYASGNVIY
                     READGLLYTIDSATGAQIGRPKKMSPNMSYAEESFSHKFASLLKYYRLETRVVLMPTY
                     KGAGRLDNVFWPGHIKAVSLEEMLDELSREDKFRDTIGGQMIRQTFNLLLKR"
BASE COUNT         1774 a          631 c         1010 g         1478 t
ORIGIN      
        1 aatacgcttt tcgtaaatcg agcgaaggct atgctatact gtaaccgtaa acaataagat
       61 ataaaaggag attgttgatg attaaataca aagaattgaa aagttatata gatgagtgga
      121 gatattattc cgatgagaac aatccaagat tggatttaga atattgcaag acgaaaattg
      181 ttgagaaagc aaaagagttt gatcttcctt gtcaaattga cgaagaacaa ataaaactcg
      241 gcggtttgtt caataaagag attgaagaat gtctagttat ttcgcaccca aatcatcaga
      301 aagactatgt aaagttttgt tttcgtttaa aaaatcaagg atcagtacaa cttctgacta
      361 tagatacttt aggtgagagt aaacaattaa aaaaatacta tatatcagaa gataataaaa
      421 gattcagaga agcaattaga gaatcggact tgtcattggg tcagaaatta ggagctcaac
      481 ttagtaactt aacagttagc ggtcttagaa ctttggggaa aaatcagagc aagattgatg
      541 cagaattaca atactgtgag tttttaacag aggtactaac acagtttaga tcaaataatg
      601 attaggagtg aaatatgagc aaagcaattg gaattgattt aggaacgact tattcagcag
      661 tatctgtatt atcagagact ggacaaccac aaattttatt gaatcaagat ggtgaaaatt
      721 taactccatc tgttgtattc tttcaggatt ttgatgggaa agatgaacca cttgttggta
      781 ttcaagctaa aaatttggca gcaagtagac ctgaagcagt tgtacagtat gtcaaaagac
      841 aaatgggaaa tccaaattgg aagtttgatt ctcctagtga tactgtttat acagcagagg
      901 aaatttcagc aatcatttta aaaagattaa aagaaggagc agaaaatgcc cttggtgaca
      961 aagtagagga tgttgtaata actgttccag cttattttga tgatgcccgt agaacagcaa
     1021 cgaaacatgc tggagaaatt gctggactta atgttttacg agttttaaat gaaccgacag
     1081 ccgctgcact tgcatacggt atatcagcag aaaaaaatga gacagtattg gtatatgatt
     1141 taggtggtgg aacttttgac gtcacattaa tgaaaataaa agatggcgag tttgatgtta
     1201 ttgccaccga tggagatcgg aatctaggag ggtttgattt tgataacgcc ttatcaatga
     1261 ttattgctga aaagatggaa gaacagggag cagaagatat ttatacggat gaacatttta
     1321 ctgccttact tcgtgaaaaa tcagagaata caaagagagg actaacaact gtagaaaaaa
     1381 caaatgtctt tctcgactat aaaggaaaaa gttataaaat tccgataaca cgtgtagaat
     1441 ttgaagaagc aacaaaaagt ctaatgaatc gtacagagga gctgttagat gatgttgttg
     1501 aagagtctgg aatgtcatgg gatgaaattg accaagtact attaataggt ggttcaactc
     1561 gaatgccaat ggtacaaaga aaattggaag agaaaattgg gaagaagatt gtatattcta
     1621 ttaatccaga tgaagctgta gcacaaggag cagctattca agcagcattg gaaatcgcta
     1681 ataaatcaga aagtgcagat gttagtgaaa cagttcgtgg attagcagaa aagttagttg
     1741 tttcggatgt cacttctcaa gccttgggaa ctctggctct ttcgaatggt gtgaaaagaa
     1801 atacaattat tattcctaaa aattccaagg taccaaacaa gtactctgag tatttttcaa
     1861 cagttgtaga taatcaacaa aatgtgttag tagaggttac tcaaggggat gacgaggatc
     1921 cgcaatttgt tacggttata ggagagagta ccattaaatt accaggtgac tggcctgcag
     1981 gaacggtttt gaaggtaact tatcattatg atgtcgatca aacagttttt gtagaggtac
     2041 atgattcgga taatcactta ttagggactt ttgaagtaga gagacaagca aatctcgata
     2101 aaagtgctgt agaagtagct agtcgtaaaa taaaagattt aactattgat taggggagga
     2161 acacaatgtc ggtcataaac tattatgaag agttagggat ttcagaaaca agttcattag
     2221 atgatgttaa gaaaagtatc aagtcaaata gaagacgcta tcgccagttg acaggttcac
     2281 caaatattga tcaaagatca atggctgaga gaaagatgga agtcattgca caggcagaaa
     2341 aagtatttga aagtgaagaa accagacaaa aatatgatag ggaattagaa aattctaaac
     2401 aaagttctga aggagtccct gattcgactc caactaatca ttcaaattca agctatcttg
     2461 attcagctag acaggccttt tattcaggaa agaaatcatt agcttattcc tacattgaag
     2521 aagccttaaa aataaatcga aatgatgcag atgtttggta tttcaaggct atgattagcc
     2581 ttgaagatag aaagttatca gatgcagaat tagctattag tgaagctaat agattgagac
     2641 ctaaaaatgc ggatatctta tctttgctag gtgatgttta ttgtgaacag aatcagcaaa
     2701 agtttgcaat tcagtattat caggaagctt ttgaactatc taataattcc ttttatcttt
     2761 tgaaaaaggg aagatcacta tttttatttg atcagtataa acaggcagta aaagatgtgc
     2821 gatatctgta tgatcattat ttagaagaaa ataaaaataa tgaagaatat atttattacc
     2881 ttttatcatg ctcttataga gaaattggag ataatgaaga agcctataat tttgcaagaa
     2941 aattagtaga tgtttcagat tcactagagc ataaactaca ttatgcaggt attctatttt
     3001 tgaaatctga agatgagtgt gagaattatt tagatacctt aaacgaacgc tatggtaaca
     3061 ataaagattt ccagcaagtg tattttaagt tactattaga tatcacgata gagcgtatga
     3121 aaaaagcacc tgatacagac gttgaggctt tctttagaaa atatattgat cgaacaaaat
     3181 atgagaatga agcagttcta gataataagg cgcgtgttcg cattgcagaa gcttacttgg
     3241 ccaaggcaca aagtttaggg attgaaaata aaattataga taatgatttt tacaatgaat
     3301 ttattgaaaa taaaaattat atcaattatg ccacaacacg ccattcacaa ggtatgggat
     3361 gtctcatgtt catcttagtt tttgcagcca attggttttt gagtggtttc tttgataagt
     3421 ttgtacatag cttttggatt agtaacgcat taagtttggc attgttatca aatattgtct
     3481 tgtattacaa ttaccctaaa ggatggcaaa taaatagaag aaagaaagga taaagttttt
     3541 atgagtgaag aagtattgca tgaaaaagtt tcgtatatcg tagataaagt tgaagatatc
     3601 gaatctttaa ttacacgccg tttattggaa gataaagcca aaaatagtct gattgaagaa
     3661 ttgaagcagt atttaatcta tagacaggat ttagataagg gtgagaaatt tgctccattt
     3721 atgaaacaga ttcttcaagt tattgatcgt attgaatcat ctgaagaaaa atcagatttg
     3781 cttacttcaa ttgctgaaga gcttctgcaa attctttcat tgaatggatt acaagttatt
     3841 gataatagtg gaatgattga cccaagtatg catgaggttg ttaatacagt agcagttact
     3901 gatgaacaaa gtgaaaataa tattgttgaa gtattgcaaa aaggatattt gttaaataac
     3961 agggttctta gaccaagtaa agtgactatt gctaaataag atatttttta ggaggtggag
     4021 aaattgttgc gcttttttaa gcatcgcaga aacatactat attttatatt aggatttctt
     4081 tggggcagaa gacaaaatgc taaggtttct ccagaaccac ctactccttc cacacctaaa
     4141 catagtgaac ttcccagtat ttccaaggca actcataatg gtaaaatgac gggatttgaa
     4201 ccacaaaaac ttaagactta tcaactttac cagcatgaat tgatgtttgg agaacctgga
     4261 aaaggattga ataaatcagg attcgatgaa tctgctgtta atcttggtca agagggtgaa
     4321 atcaattttg ctaaagcatt acaaaaaaaa gggcttttag aaaaactagt taccttttgg
     4381 tctgttcata atctcaattt agaagatgaa agggtagatg cggatattga ttgtgttatt
     4441 gtttctggat ctacaatttg gttagtagat ttaaaatttt atgcttcagg aaatgtgatt
     4501 tatagagaag cggatggttt attgtacact atagatagtg ctacaggtgc tcaaataggc
     4561 agacctaaaa aaatgtcccc taacatgtct tatgcagaag aaagcttttc ccataaattt
     4621 gcgagtttat taaaatatta tcgcttggaa acacgtgttg tcttaatgcc tacctataag
     4681 ggtgcaggta gattggataa tgtcttttgg ccaggtcata ttaaggctgt tagtctagaa
     4741 gagatgttag atgagttatc tagggaagat aagtttaggg atacaattgg tgggcagatg
     4801 attcggcaga catttaattt acttttgaaa cgttaaatta tgtaaaaata gtaaagaatt
     4861 gatgttgtag attttttata tgagttatat ttt
//
LOCUS       DAVLCS010000077         4434 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLCS010000077 DAVLCS010000000
VERSION     DAVLCS010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.077"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            82..1107
                     /locus_tag="VXC78_002035"
     CDS             82..1107
                     /locus_tag="VXC78_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0584030.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1097..2104
                     /locus_tag="VXC78_002036"
     CDS             1097..2104
                     /locus_tag="VXC78_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0584031.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2104..3111
                     /locus_tag="VXC78_002037"
     CDS             2104..3111
                     /locus_tag="VXC78_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0584032.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3111..3905
                     /locus_tag="VXC78_002038"
     CDS             3111..3905
                     /locus_tag="VXC78_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0584033.1"
                     /translation="MKGLWSNDLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVMANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
BASE COUNT         1603 a          639 c          751 g         1441 t
ORIGIN      
        1 ttattaaatt tgtaactgta tctattgaca atgataatta ttatcgatac aatagacttg
       61 aaatatgttt aaggagtttt tatgaaaaac aaattttttc taatagctat tttagctatg
      121 tgtatagttt ttagcgcttg ttcttctaat tctgttaaaa atgaagaaaa tacttctaaa
      181 gagcatgcgc ctgataaaat agttttagat catgctttcg gtcaaactat attagataaa
      241 aaacctgaaa gagttgcaac tattgcttgg ggaaatcatg atgtagcatt agctttagga
      301 atagttcctg ttggattttc aaaagcaaat tacggtgtaa gtgctgataa aggagtttta
      361 ccatggacag aagaaaaaat caaagagcta aatggtaaag ctaacctatt tgacgatttg
      421 gatggactta actttgaagc aatatcaaat tctaaaccag atgttatctt agcaggttat
      481 tctggtataa ctaaagaaga ttatgacact ctatcaaaaa ttgctcctgt agcagcatac
      541 aaatctaaac cttggcaaac tttatggaga gatatgatta aaattgattc aaaagcctta
      601 ggtatggaaa aagaaggtga tgagttaatc aaaaatactg aagctcgtat atccaaagaa
      661 ttagaaaaac atccagaaat caaaggaaaa atcaaaggaa aaaaagtatt atttactatg
      721 attaatgctg cagatacatc aaaattctgg atttatacta gcaaagatcc aagagcaaat
      781 tatttaacag atttaggtct agttttccct gaatcattaa aagaatttga gagtgaagat
      841 agttttgcaa aggaaatttc tgcagaagaa gcaaataaga taaatgatgc tgatgtaatc
      901 ataacttatg gtgatgataa aactcttgaa gctttacaaa aagatcctct tttaggtaaa
      961 ataaatgcaa ttaaaaatgg tgccgttgct gtaattccag ataatacacc gttagcagcc
     1021 tcatgcactc caacaccact ttcaataaac tatactattg aagaatatct aaatctttta
     1081 ggaaatgcat gcaaaaatgc gaaataaaaa acaaataaac ctaggcataa tttttgtaat
     1141 ctgcctaggt cttcttatta caatattttt gtcattaaag cttggaacaa aagaaattaa
     1201 tatcagagat tttttagcag cttttggaat gggtaataca aatgatgatt ttattaaatc
     1261 aattatatat aaaagaatac ctagaactat ttttgcaatt ttagcaggtt ctagtcttgc
     1321 cataagcggt gtattgatgc aatcagttac tagaaaccca atagctgatc caggtatact
     1381 tggtataaac acaggagcaa gtcttagtgt agtaattggt ctttcttttt taggaatttc
     1441 atcaagcata agccatataa gttttgcaat cattggtggc ttagtaagtg caatttttgt
     1501 atacgcgatt gctgtaagcg gaaaagcagg ccttacccct ataaaacttg ccttatcagg
     1561 aacttgtgtt agtatggctt taagcagttt tgtaagtttt ttaattttac cgaataataa
     1621 cgtcttagac aaatttagat tttggcaaat aggtagcctt ggagcagcta cattatcttc
     1681 tatatctaca ctactacctt ttataatttt aggtcacttg atagctatat ttatttcatc
     1741 agatttaaac gctttagcta tgggtgatga aatggctgtt ggtcttggag ttaatgttaa
     1801 taggataaga tcacttgcaa taattgcaag tgtgctttta tgttcaagta ttactgcaat
     1861 tggtggacct attggcttcg taggtcttat agttcctcac ttttgtggct tatttataag
     1921 caaagatata cgcacaatga ccatttcttc atcttttata ggtgcagagc tcttgcttat
     1981 atgtgatata atcggccgta tgttaggtaa accaggtgaa attgaagtag ggataattac
     2041 tgcaataatc gggggtccag tacttattta tgtaactatg aaaaatagag gggttaataa
     2101 ctaatgcaaa atttaattat aggtattcaa aaaagaaaaa atagaataac actattctcc
     2161 tcactatttt tattaataat aatcagtcta tcatttttca ttttacttat cggagatgaa
     2221 agttattctt tttcaacttt gattaaagtc ttaaatagtg aaactgttcc tggagctagt
     2281 ttttcgatta tggaaattag attaccaaaa ttattagcag gaattatagc tggctggtct
     2341 tttggattgg caggatttat ctttcaaact atgttaagaa atcctcttgc aagtcctgat
     2401 ataatcggtg tcacaagttc ttcatctatt gcagcggtct tttgcatatt ggtattaaaa
     2461 acaaatagtt taactactgg aattatttca ataacttgtg gactaacatc atctttaata
     2521 ttatttttac tagctaaaaa agatggtttt tcagcagcaa gactgataat attaggtatt
     2581 ggttttcaag ctgtcacaag agcaggcacc tcatttttat tgttgaaagt agcaagatat
     2641 gaattacaag aagttatgag atggctcagt ggctctttat cttttacaaa gttagatgac
     2701 atacctcttg ttctaatagt aagtattatt gctactatat tagttttatt ttttaataaa
     2761 agactagaaa ttattgaact tggtgaagaa atagcaatcg gacttggagc aaatcccgag
     2821 ctttcaaggc ttgttttaat tttttgcgct gtatctttaa ctgctttttc tacttcaatt
     2881 acaggaccaa tagcttgtat atctttttta gctggtccca tagccttaaa tattggtaag
     2941 aaaagaagcc caatattagc tggattggtt ggaattttac tagttttgtt atcagacata
     3001 ttctctcaaa atattttacc agctagatat ccagtaggtg ttgtaactgg cttgttaggt
     3061 tcaccatact taatatactt actaataaaa atgaacagga gaaatatata atgaaaggtc
     3121 tgtggtcaaa tgatcttacc tgcggttatg atgaaaaaat aatcttggaa aatataaata
     3181 taaaaatacc tgaagaaaaa atatcagtta ttattgggtc aaatggttgt gggaaatcaa
     3241 cactcattaa aaccttgtct cgacttataa agccattaga gggagaagta ttgcttgata
     3301 ataaatcaat taattcttat aaagaaaaag atttagcaaa acacatagct atattacctc
     3361 aatctccaat aatccctgaa tcaataacag tagctgatct tgtaagccgt ggtcgtttcc
     3421 cctacagaaa gccttttaag agtcttggaa aagatgacct tgaaataata aacagatcaa
     3481 tggttatggc caatgttgaa gatctagcaa ataacctagt tgaagaactt tctgggggtc
     3541 aaaggcaaag agtatggata gctctagccc tagcccaaga tacaagtatc ctacttttag
     3601 atgagccaac tacttacttg gatatctcat atcaaataga actattagac ctcttgactg
     3661 atctaaacca aaaatataag acaaccattt gcatgatttt gcacgatata aatctaacag
     3721 caagatacgc tgattaccta tttgcaatta aagaaggtaa acttgttgca gagggaaagc
     3781 ctgaagatat actaaatgat aaactagtta aagatatctt taatcttgaa gcaaaaatta
     3841 tacgtgaccc tatttccaat tcgcctctaa tgattcctat tggcaagcac catgttagct
     3901 cttaataatt gaatattgga attcatttaa aagtcgcaaa ttttgaactg accctcaaaa
     3961 gttaggccaa aaaactaact aaaggaggtc agttttttaa tggcaaatac agcacagaat
     4021 ttaagataaa attagtaaaa gaatatcatg aatgaaaaat aggatataga gaataacagc
     4081 aatattaaaa agatcaggac tgataataaa caaaaagaaa gtacaacgac tagttcaaaa
     4141 gctaaaactt caagtaaaaa gttattcaag aaaatctaga aaatactcat cctacaaagg
     4201 acaggtagga aaaatatcgg acaacaaaat aaaaagaaat atttattacc gaaaaaaagg
     4261 ggaaatcgag tcaagtacca acaggctcat ctattccaaa aagatattta ctcgatggaa
     4321 aaactcctag aattagtgct acaaatattg acaatggtat cttaggttac tacgaagata
     4381 tagatgataa aaattataga gtttttgaaa attttatatc tgtttcattt ttag
//
LOCUS       DAVLCS010000078         4070 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLCS010000078 DAVLCS010000000
VERSION     DAVLCS010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.078"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            416..643
                     /locus_tag="VXC78_002039"
     CDS             416..643
                     /locus_tag="VXC78_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584034.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            931..3876
                     /locus_tag="VXC78_002040"
     CDS             931..3876
                     /locus_tag="VXC78_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEV0584035.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGSSTLTDTEKSQPSEEGENITLPAEHVESVSETELSGNKQEQERKDK
                     QEEKIPRDYYARDLENVETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFK
                     PDAKAPAFYNLFSVSSATKKDEYFTMAVYNNTATLEGRGSDGQQFYGNYNDAPLKVKP
                     GQWNSVTFTVEKPTAELPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRA
                     NNTVWGSNLQIRNLTVYNRALTPEEVQKRSQLFKRSDLEKKLPEGAVLTEKTDIFESG
                     RNGKPNKDGIKSYRIPALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWG
                     DKVVISNLRDNPEAKDPAAPSPLNIDMVLVQDPTTKRIFSIYDMFPEGRAVFGMPKTP
                     EKAYEKIGDKTYQILYKQGESGHYTVRENGEVYNAQNQKTDYRVVVNPTEPGYRDKGN
                     LYKGQELIGNIYFAHSTKNPFRVANTSYLWMSYSDDDGKTWSAPRDITPGLRKDWMKF
                     LGTGPGTGIVLRNGPHKGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVN
                     DNRQVDGQKIHSSTMNNRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTW
                     EKDIKRYPQVKDVYVQMSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTW
                     LKHNPIQKGEFAYNSLQELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKNLISPT
                     EAKVKRTREMGKGEMGKGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFA
                     VDKEDIGQEIIGIAKGSIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGIE
                     PAVHEIAEYKGSDSLVTLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGL
                     FTLGKKREQ"
BASE COUNT         1392 a          655 c          907 g         1116 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagctg acttcgtcag tcttatctac
       61 aacctcaaaa cagtgttttg agcatcatgc ggctagcttc ttagtttgct ctttgatttt
      121 cattgagtat aaaaacagat gagtttctgt tttcttttta tggactataa atgttcagct
      181 gaaactactt tcaaggacat tattatataa aagaattttt tgaaactaaa atctactata
      241 ttacactata ttgaaagcgt tttaaaaatg aggtataata aatttattaa cacttataaa
      301 aagtgataga atctatcttt atgtatattt aaagatagat tgctgtaaaa atagtagtag
      361 ctatgcgaaa taacagatag agagaaggga ttgaagctta gaaaagggga ataatatgat
      421 atttaaggca ttcaagacaa aaaagcagag aaaaagacaa gttgaactac ttttgacagt
      481 ttttttcgac agttttctga ttgatttatt tcttcactta tttgggattg tcccctttaa
      541 gctggataag attctgattg tgagcttgat tatatttccc attatttcta caagtattta
      601 tgcttatgaa aagctatttg aaaaagtgtt cgataaggat tgagcaggaa gtatggtgta
      661 aatagcataa gctgatgtcc atcatttgct tataaagaga tattttagtt taattgcagt
      721 ggtgtcctgg tagataaact agattggcag gagtctgatt ggagaaagga gaggggaaaa
      781 ttggcaccaa tttgagatag tttgtttagt tcatttttgt catttaaatg aactgtagta
      841 aaagaaagtt aataaaagac aaactaagtg cattttctgg agtaaatgtc ttatttcaga
      901 aatcgggata tagatataga gaggatcagt atgaatcgga gtgttcaaga acgtaagtgt
      961 cgttatagca ttaggaaact atcggtagga gcggtttcta tgattgtagg agcagtggta
     1021 tttggaacgt ctcctgtttt agctcaagaa ggggcaagtg agcaacctct ggcaaatgaa
     1081 actcaacttt cgggggggag ctcaacccta actgatacag aaaagagcca gccttctgag
     1141 gaaggagaaa atataactct tcctgcagag catgtagagt ctgtttcaga gactgaactt
     1201 tctggcaata agcaagaaca agaaaggaaa gataagcaag aagaaaaaat tccaagagat
     1261 tactatgcac gagatttgga aaatgtcgaa acagtgatag aaaaagaaga tgttgaaacc
     1321 aatgcttcaa atggtcagag agttgattta tcaagtgaac tagataaact aaagaaactt
     1381 gaaaacgcaa cagttcacat ggagtttaag ccagatgcca aggccccagc attctataat
     1441 ctcttttctg tgtcaagtgc tactaaaaaa gatgagtact tcactatggc agtttacaat
     1501 aatactgcta ctctagaggg gcgtggttcg gatgggcaac agttttacgg taattacaac
     1561 gatgcaccct taaaagttaa accaggtcag tggaattctg tgactttcac agttgaaaaa
     1621 ccgacagcag aactacctaa aggccgagtg cgcctctacg taaacggggt attatctcga
     1681 acaagtctga aatctggcaa tttcattaaa gatatgccag atgtaacgca tgtgcaaatc
     1741 ggagcaacca agcgtgccaa caatacggtt tgggggtcaa atctacagat tcggaatctc
     1801 actgtgtata atcgtgcttt aacaccagaa gaggtacaaa aacgtagtca actttttaaa
     1861 cgctcagatt tagaaaaaaa actacctgaa ggagcggttt taacagagaa aacggacata
     1921 ttcgaaagcg ggcgtaacgg taaaccaaat aaagatggaa tcaagagtta tcgtattcca
     1981 gcacttctca agacagataa aggaactttg atcgcaggtg cagatgaacg ccgtctccat
     2041 tcgagtgact ggggtgatat cggtatggtc atcagacgta gtgaagataa tggaaagaca
     2101 tggggagata aggtggttat ctccaatctt cgagataatc ctgaagctaa agatcctgct
     2161 gcgccatcgc ctctaaatat tgatatggtt ttggttcaag acccgacaac aaagagaatc
     2221 ttctcaattt atgatatgtt cccagaaggt cgagcagttt ttggaatgcc aaaaacacct
     2281 gaaaaagctt atgaaaagat aggggataaa acttatcaaa tcttgtataa acaaggagag
     2341 tctggtcatt atactgttcg tgagaatgga gaagtgtata atgcacaaaa tcaaaagacg
     2401 gattatcgtg ttgtagtgaa tccaacagaa cctggctata gagataaagg aaatctttac
     2461 aaaggtcagg aattgattgg aaatatctat tttgcacaca gtacaaaaaa tccatttaga
     2521 gtagccaata cgagctatct atggatgtca tatagtgacg atgatggtaa aacttggtct
     2581 gcaccgagag atattactcc aggtcttcgc aaggattgga tgaagttcct aggaacaggt
     2641 cctggaacag gaattgtact tcggaatggg cctcacaagg gacggatttt gataccggtt
     2701 tatacgacta ataatgtatc tcacttagat ggctcgcaat cttctcgtgt catctattca
     2761 gatgatcatg gaaaaacttg gcatgctgga gaagcggtca acgataaccg tcaggtagac
     2821 ggtcaaaaga tccactcttc tacgatgaac aatagacgtg cgcaaaatac agaatcaacg
     2881 gtggtacaac taaacaatgg agatgttaaa ctctttatgc gtggtttgac tggagatctt
     2941 caggttgcta caagtaaaga cggaggagtg acttgggaga aggatatcaa acgttatcca
     3001 caggttaaag atgtctatgt tcaaatgtct gctatccata cgatgcacga aggaaaagaa
     3061 tacattatcc tcagcaatgc aggtggaccg aaacgtgaaa atgggatggt ccacttggca
     3121 cgtgtcgaag aaaatggtga gttgacttgg ctcaaacaca atccaattca aaaaggagag
     3181 tttgcctata attcgctcca agaattagga aatggggagt atggtatctt gtatgaacat
     3241 actgaaaaag gacaaaatgc ctatacccta tcatttagaa aatttaattg ggactttttg
     3301 agcaaaaatc tgatttctcc taccgaagcg aaagtgaagc gaactagaga gatgggcaaa
     3361 ggagagatgg gcaaaggagt tattggcttg gagttcgact cagaagtatt ggtcaacaag
     3421 gctccaaccc ttcaattggc aaatggtaaa acagcgactt tcctaaccca gtatgatagc
     3481 aagaccttgt tgtttgcagt agataaggaa gatatcggac aggaaattat tggtatagct
     3541 aaaggaagca tcgaaagtat gcataatctt cctgtaaatc tagcaggtgc cagagttcct
     3601 ggcggagtaa atggtagcaa agcagcggtg catgaagttc cagaatttac agggggagtt
     3661 aatggtatag agccagctgt tcatgaaatc gcagagtata agggatctga ttcgcttgta
     3721 actcttacta caaaagaaga ttatacttac aaagctcctc ttgctcagca ggcacttcct
     3781 gaaacaggaa acaaggagag tgacctccta gcttcactag gactaacagc tttcttcctt
     3841 ggtctgttta cgctagggaa aaagagagaa caataagaga agaattctaa acatttgatt
     3901 ttgtaaaaat agaaggagat agcaggtttt taagcctgct atcttttttt gatgacattc
     3961 aggctgatac gaaatcataa gaggtctgaa actactttca gagtagtctg ttctataaaa
     4021 tatagtagat tgaaataaga tgtgaacaac tctatcagga aagtcaaatt
//
LOCUS       DAVLCS010000079         4041 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLCS010000079 DAVLCS010000000
VERSION     DAVLCS010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4041
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.079"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(<1..103)
                     /locus_tag="VXC78_002041"
     CDS             complement(<1..103)
                     /locus_tag="VXC78_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0584036.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNT"
     gene            complement(289..900)
                     /gene="rpsD"
                     /locus_tag="VXC78_002042"
     CDS             complement(289..900)
                     /gene="rpsD"
                     /locus_tag="VXC78_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV0584037.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1095..2147)
                     /locus_tag="VXC78_002043"
     CDS             complement(1095..2147)
                     /locus_tag="VXC78_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0584038.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2144..2842)
                     /locus_tag="VXC78_002044"
     CDS             complement(2144..2842)
                     /locus_tag="VXC78_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0584039.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(3009..>4041)
                     /gene="pavB"
                     /locus_tag="VXC78_002045"
     CDS             complement(3009..>4041)
                     /gene="pavB"
                     /locus_tag="VXC78_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV0584040.1"
                     /translation="DNGDAKNPALSPLGENVKTKGQYFYQVALDGNVAGKEKQALIDQ
                     FRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTININGLISKETVQKAVADNVKDS
                     IDVPAAYLEKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNP
                     ALSPLGENVKTKGQYFYQLALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGK
                     PDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTM
                     TSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGL
                     GLKNKKEEN"
BASE COUNT         1086 a          892 c          798 g         1265 t
ORIGIN      
        1 tggtattacg tgagatttgg aaaacgtgtg atgcttctgt tatactacct gttcgctcac
       61 aataagagag aactttttta cgaaaatcta ttgaatatgc cataaaagga ttataccaca
      121 ttgtgtacta tttttggttc attttactat atcactttgg actatatcgg tctagttatg
      181 tctcaacgat tatagctgga tactaagaga aatcaaaaaa gcactaaggg agaacgtccc
      241 aaagtgctta atatcaaggc ctcaaagtct atcttattca ataaaatatt acaacatttt
      301 gttgtagaat tcaacgacaa gtgcttcgtt gatttctggg ttgatttcgt cgcgttctgg
      361 caagcgagtc aatgaacctt ccaacttttc agcgtcgaat gatacgaatg ctggacgtcc
      421 aagagtagct tctactgctt caaggattgc tggaactttc aatgattttt cacgaactga
      481 gatcacttga cctggagtta cacggtatga tgggatatca acgcgtttcc cgtcaacaag
      541 gatgtgaccg tggtttacga attgacgagc ttgacgacga gtagtcgcga gaccaagacg
      601 gtaaacaacg ttatccaaac gacgttccaa aagaagcata aagttgaaac ctaggattcc
      661 gcctttgatt tttgtagctt gtacgaacaa gttacggaat tgtttttcac ctacaccgta
      721 agtgaaacga agtttttgtt tttcagccaa ttgcaaaccg tattctgaca atttagaacg
      781 gttgtttggt ccgtgttgtc ctggtacgta gttacgacgt gccaattctt tacctgtacc
      841 tgtaagtgaa aggccaaggc gacgagcttg tttccaagat ggtcctgtat aacgtgacat
      901 atgaatgtcc tcctgatata aataatattt cggtggaaat agtcacttag aaagccctga
      961 ttcgtgcaga tgcccttcgc ctaaacagcc aaggttactt gtcataagac acctgttgac
     1021 gagcttcatg ctttcctgct gatatttcac acaaaatcta ttctaccatg aatagctgga
     1081 tttgtaaagg ggttttaggc tttattttca ctaccagaga ggttgagaac gagggtaaag
     1141 gtacttccta gaccgtactg gctgctgact gtgatttccc cacccaattg atgggccaat
     1201 tcacgcgcaa tcgcaagtcc taatccatga ccacctgtct tcatgttacg cgaagtttcg
     1261 acacgataaa gacgtttgaa aatattttcc aaatcctctg gggcaatacc ctgcccttca
     1321 tcggtcacac tgattgaaag ctggtccttc tccagcttag ccaccacttc cagcttggtt
     1381 cctggagcag aatatttaaa agcgttatcg accagattca ccaagatacg agaaagctta
     1441 gcataatctc cctcaatccg ggcagactct gggattacct gcaagtggac atctcttctc
     1501 tcctgctcaa tcaaaaactg aaattcactc atgcactcaa ttaagagctt gtccagaaaa
     1561 atactgtctt tactggtagt ttccacctga ttcctagctg tgtttagggt caaaaaattc
     1621 aactcctcaa ccagtttatt gagcctctcc gtctggcgtc caatggttgc tagataatga
     1681 gcttgctccg actccttgat aatcccatcc aaaatccctt ctaccgtcgc ttggatcgaa
     1741 gtgataggag tcttaatatc atgcgacaac tgggcaatca tcaagccctt ttctcgttcg
     1801 ctttcttcca aggaatcaaa gcttacctgc aaatcatggg acatctcatt aaaagtttgc
     1861 cctaattgct gaaattctac aggaccttga acctccaaat ttgaaggaaa atccttggcc
     1921 gctacccgct tggcatgctc cttgagtttg cccaacgacg taaagactgg caataggaga
     1981 aagagactaa tcccagcacc gacaaggctg gcaacgatgg tcatcccaag caaaaagtaa
     2041 atctcgcctt tcgcaatcag cattttttga acagcccaaa aaacaaccaa aatggttaag
     2101 agggttgaaa taatatatcc aaccaaaata taacttttta gtttcatgtt tgtcctctcg
     2161 gtttctctat cttatatccc aacccccaaa ctgtcttaat agtgggcgtt tggtcactac
     2221 tatattttgc cagctcctgt cgaagagcat ggatatgcac attcaaggta ttggtgtcat
     2281 ccacgtagtc ttctttccag atcttttcat agaggtctgt cttggagaaa actcgctctg
     2341 gattgctagc taaaatccac agcaattcaa atgatttaac agttaaatcc agcatttctt
     2401 ctcctatttg aacttcatga ctactatgat tcatttttag attgccaagg gaaatcagct
     2461 ctgtttcgcc cccacgatga aggcggcgca aaatattgtg gacacgcaaa accagctcac
     2521 gtgggctaaa aggcttagca ataaaatcat ctgctcccaa gctcaggccg taaatcttgt
     2581 cctgttcact ggtcttagca gtaataaata ggaaaggctg ctctggtgat aagtattgaa
     2641 cctcactgat taaatcataa ccatccatcc gaggcatcat gacatctgtg ataatcaaat
     2701 caatcggttt tttcttgaac agctctagcg cttccagtcc atcatgggct accaagacct
     2761 gataacctgc ctgaattaag tatctctgat gaatatctgt gatttctacc tcgtcgtcaa
     2821 cgagtaaaat tgtctttccc atctgtctct cctttgataa aaacagtgct atactgcttt
     2881 aagtataaca ctatttttat tgttttacga tgattttaat ctgctattga aagaaagtcc
     2941 tgattgctga ttgagttgtt aaactaatct tagtcagccc actatccatc atttatttcc
     3001 ttagctgatt agttttcttc ttttttgttt ttcaaaccta gaccaccgag taaacctgca
     3061 agcgcaagcc caaggaaacc aatacttgcc attgatgttt gagtctcacc agtatttggt
     3121 agcatagctt tatcctctga catcatcgta tcagacatct tgttagcaga agcagccatg
     3181 ttttcacctg ccatcgtgtt ggtagaactt gtcatggtgt cagcaggcat gctatctgta
     3241 gtacctgtag catgattgtg attcatcgga gtcacgccag aaccagagtt agaaggtgat
     3301 aatgaaccat ttgctgtgtc tgatgtttct ttaacattta tcttaatagt gactttttta
     3361 gttgctacga tgttgtccaa atctggttta ccgtctttgt taccatagac attgactgta
     3421 gcgctgtaag tttgagtacc gtttgctcgg aactggtcaa tgagcgcttg tttttctttg
     3481 ccagctacat ttccgtccaa ggctaattga tagaagtatt gacctttggt cttcacgttt
     3541 tcacctagtg gagatagggc tgggttttta gcgtcaccgt tatctgacca tggtgccttg
     3601 tcagatgcct tgagcaagag acgagtcaac ataccatcac ctgcgaagag ttcgtatgga
     3661 atcacatggt tgacacctgc tgtgaatgga ccttcaccct tggctttttc taggtaggct
     3721 gctggaacat cgatactgtc cttaacgttg tctgcaacgg ctttttgaac tgtttcttta
     3781 gaaattaaac cgtttatgtt aatagtgact tttttagttg ctacgatgtt gtccaaatct
     3841 ggtttaccgt ctttgttacc atagacattg actgtagcgc tgtaagtttg agtaccattt
     3901 gctcggaact ggtcaatgag cgcttgtttt tctttgccag ctacatttcc gtccaaggct
     3961 acttgataga agtattgacc tttggtcttc acgttttcac ctagtggaga tagggctggg
     4021 tttttagcgt caccgttatc t
//
LOCUS       DAVLCS010000080         3874 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLCS010000080 DAVLCS010000000
VERSION     DAVLCS010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3874
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.080"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            214..477
                     /locus_tag="VXC78_002046"
     CDS             214..477
                     /locus_tag="VXC78_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV0584041.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            483..2216
                     /gene="ptsP"
                     /locus_tag="VXC78_002047"
     CDS             483..2216
                     /gene="ptsP"
                     /locus_tag="VXC78_002047"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV0584042.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            2471..>3874
                     /locus_tag="VXC78_002048"
     CDS             2471..>3874
                     /locus_tag="VXC78_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0584043.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKAY"
BASE COUNT         1279 a          758 c          826 g         1011 t
ORIGIN      
        1 aatagcaatg attatcctat aaattgtttt tgaagaaact atatcctgtg ttttgttatc
       61 taggatagaa gattttcagc aagttatctg aaaggaaatt gaaggaaaat ccagaaaatg
      121 cttgaaaaaa atcctagaag atggtataat actaaattgt aagggttatc acatataact
      181 caaaaaaaga aagaacaaaa ggagagtcaa actatggctt ctaaagattt ccacgtagtg
      241 gcagaaacag gtattcacgc acgtccagca acattgttgg tacaaactgc tagcaaattt
      301 gcttcagata tcactcttga gtacaaaggt aaatcagtta accttaaatc aattatgggt
      361 gttatgagtc ttggtgttgg tcaaggtgct gacgtaacta tctcagctga aggtgcagat
      421 gcagatgacg ctatcgctgc aatctcagaa acaatggaaa aagaaggatt ggcataaggg
      481 aaatgacaga aatgcttaaa ggaatcgcag catctgacgg tgttgcagtt gcaaaagcat
      541 atctactcgt tcagccggat ttgtcatttg agactattac agtcgaagat acaaacgcag
      601 aagaagctcg ccttgatgcc gctctacagg catcacaaga cgagctttct gttattcgcg
      661 agaaagcagt aggtacgctc ggtgaagaag cagctcaagt ttttgatgct cacttaatgg
      721 ttcttgctga cccagaaatg atcagccaaa tcaaggaaac tatccgtgcg aagaaagtga
      781 atgcagaagc aggtctgaaa gaagttacag atatgtttat cactatcttt gaaggcatgg
      841 aagacaaccc atacatgcaa gaacgcgcag cggatatccg cgacgtgaca aaacgtgtat
      901 tggcaaacct tcttggtaaa aaattgccaa acccagcttc tatcaatgaa gaagtgattg
      961 tgattgcgca tgacttgact ccttcagata cagctcaatt ggacaaaaac tttgtaaaag
     1021 cttttgtaac caacattggt ggacgtacaa gccactcagc tatcatggca cgtacacttg
     1081 aaattgctgc tgtattaggt acaaacaaca tcactgaaat cgttaaagac ggtgacatcc
     1141 ttgctgttaa cgggatcact ggagaagtga ttatcaaccc gacagatgaa caagcggcag
     1201 aatttaaagc agctggtgaa gcctatgcga aacaaaaagc tgaatgggca cttttgaaag
     1261 atgctcaaac agtgactgct gacggtaaac acttcgagtt ggctgccaat attggtactc
     1321 caaaagacgt tgaaggtgtt aacaacaacg gtgcagaagc tgttggactt taccgtacag
     1381 agttcttgta catggattct caagacttcc caactgaaga tgagcagtat gaagcataca
     1441 aggctgttct tgaaggaatg aacggtaaac ctgttgtcgt tcgtacaatg gatatcggtg
     1501 gagataagga acttccttac ttcgatatgc ctcacgaaat gaacccattc cttggattcc
     1561 gtgctcttcg tatctctatc tctgagactg gagatgctat gttccgcaca caaatccgtg
     1621 ctcttcttcg tgcgtctgtt cacggtcaat tgcgtatcat gttcccaatg gttgcgctct
     1681 tgaaagaatt ccgtgcagcg aaagcagtct ttgatgaaga aaaagcaaac cttcttgctg
     1741 aaggtgttgc agttgcggat aacatccaag ttggtatcat gatcgagatt cctgcagcgg
     1801 ctatgcttgc agaccaattt gctaaagaag ttgacttctt ctcaattggt acaaacgact
     1861 tgatccaata tacaatggca gcagaccgta tgaacgaaca agtttcatac ctttaccaac
     1921 catacaaccc atcaatccta cgcttgatta acaatgtgat caaagcagct cacgctgaag
     1981 gtaaatgggc tggtatgtgt ggtgagatgg ctggtgacca acaagctgtt ccacttcttg
     2041 tcggaatggg cttggatgag ttctctatgt cagcaacatc tgtacttcgt acacgcagct
     2101 tgatgaagaa actcgacaca gctaagatgg aagagtacgc aaaccgtgcc cttacagaat
     2161 gctcaacaat ggaagaagtt cttgaacttc aaaaagaata cgttaatttt gattaatcga
     2221 aaagtccctg caactcagtt acagggactt tttttgatat tttaaaaaga attttcaaga
     2281 aaatctttct tataaaaagt ccaaccttga aaaagtagtg gtcagaacaa aaaatactta
     2341 aatggttcat aaaattcttg acaagttgga gatttaggag taaactatta accagttaag
     2401 taatagagag gagtttctgc aatttagaaa tgaattgcaa ctagaaatat caaatagaaa
     2461 gagagtttcg atgaaaatta ataagaaata ccttgttggt tctgcggcag ctttgatttt
     2521 aagtgtttgt tcttacgagt tgggactgta tcaagctaga acggttaagg aaaataatcg
     2581 tgtttcctat atagatggaa aacaagcgac gcaaaaaacg gagaatttga ctcctgatga
     2641 ggttagcaag cgtgaaggaa tcaatgctga gcaaatcgtc atcaagataa cagaccaagg
     2701 ctatgtcact tcacatggcg accactatca ttattacaat ggtaaggttc cttatgatgc
     2761 gattttcagt gaagaattac tcatgaaaga tccaaactat aagctaaaag atgaggatat
     2821 tgttaatgag gtcaagggtg gatatgttat caaggtagat ggaaaatact atgtttacct
     2881 taaggatgct gcccacgcgg ataacgtccg tacaaaagag gaaatcaatc gacaaaaaca
     2941 agaacatagt caacatcgtg aaggtgggac tccaagaaac gatggtgctg ttgccttggc
     3001 acgttcgcaa ggacgctata ctacagatga tggttatatc tttaatgctt ctgatatcat
     3061 agaggatact ggtgatgctt atatcgttcc tcatggagat cattaccatt acattcctaa
     3121 gaatgagtta tcagctagcg agttagctgc tgcagaagcc ttcctatctg gtcggggaaa
     3181 tctgtcaaat tcaagaacct atcgccgaca aaatagcgat aacacttcaa gaacaaactg
     3241 gctaccttct gtaagcaatc caggaactac aaatactaac acaagcaaca acagcaacac
     3301 taacagtcaa gcaagtcaaa gtaatgacat tgatagtctc ttgaaacagc tctacaaact
     3361 gcctttgagt caacgccatg tagaatctga tggccttgtt ttcgacccag cgcaaatcac
     3421 aagtcgaacc gccagaggtg tagctgtccc tcatggtaac cattaccact ttatccctta
     3481 tgaacaaatg tctgaattgg aaaaacgaat tgctcgtatt attccccttc gttatcgttc
     3541 aaaccattgg gtaccagatt caagaccaga acaaccaagt ccacaatcga ctccggaacc
     3601 tagtccaagt ctgcaacctg caccaaatcc tcaaccagct ccaagcaatc caattgatga
     3661 gaaattggtc aaagaagctg ttcgaaaagt aggcgatggt tatgtctttg aggagaatgg
     3721 agtttctcgt tatatcccag ccaaggatct ttcagcagaa acagcagcag gcattgatag
     3781 caaactggcc aagcaggaaa gtttatctca taagctagga gctaagaaaa ctgacctccc
     3841 atctagtgat cgagaatttt acaataaggc ttat
//
LOCUS       DAVLCS010000081         3752 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLCS010000081 DAVLCS010000000
VERSION     DAVLCS010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.081"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            28..>3752
                     /locus_tag="VXC78_002049"
     CDS             28..>3752
                     /locus_tag="VXC78_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0584044.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPE
                     QVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEALKEYTGKIEQPSAE
                     DTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTGVGSATFIAPNVLLTVAHNFI
                     NNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVIKL
                     PETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLKDATVEMEQEYANNTYGVQYQ
                     GGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVYDE
                     LYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGNKYRHVTSLASLPSNAENYFM
                     KVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLIQHENNNVLENYTYYLPKTQQ
                     SETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELPDGQESYVNNVFHGILVGTNN
                     EKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHADG
                     AIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLIDKS
                     FASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNLWDP
                     VGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGTYSNKNNKVVNVVQEDDEILT
                     KDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDFNFSS"
BASE COUNT         1427 a          553 c          758 g         1014 t
ORIGIN      
        1 atataaattt tatttcaagg aggaataatg gaaaagtatt ttggtgaaaa acaagagcgt
       61 ttttcattta gaaaattatc agtaggactt gtatctgcaa cgatttcaag tttatttttt
      121 atgtctgtat tagctagttc atctgtggat gctcaagaaa ctgcgggagt tcactataaa
      181 tatgtggcag attcagagct atcatcagaa gaaaagaagc agcttgtcta tgatattccg
      241 acatacgtgg agaatgatga tgaaacttat tatcttgttt ataagttaaa ttctcaaaat
      301 caactggcgg aattaccaaa tactggaagc aagaatgaga ggcaagccct agttgctggt
      361 gctagcttag ctgctctggg aattttaatt tttgctgttt ccaagaaaaa ggttaagaat
      421 aaaacggtat tacatttagt attggttgcg ggaatgggaa atggtgtctt agtttcagtc
      481 catgctttag aaaatcatct tttgctaaat tacaatacgg actatgaatt gacctctgga
      541 gaaaaattac ctcttcctaa agagatttca ggttacactt atattggata tatcaaagag
      601 ggaaaaacga cttctgattt tgaagtaagt aatcaagaaa aatcagcagc cactcctaca
      661 aaacaacaaa aggtggatta taatgttaca ccaaattttg tagaccatcc atcaacagta
      721 caagctattc aggaacaaac acctgtttct tcaactaagc cgacagaagt tcaagtagtt
      781 gaaaaacctt tctctactga attaatcaat ccaagaaaag aagagaaaca atcttcagat
      841 tctcaagaac aattagccga acataagaat ctagaaacga agaaagagga gaagatttct
      901 ccaaaggaaa agactggggt aaatacatta aatccacagg atgaagtgct atcaggtcag
      961 ttgaacaaac cggaactctt atatcgtgac gaaactatag aaacaaaaat agattttcaa
     1021 gaagaaattc aagaaaatcc tgatttagca gaaggaactg taagagtaaa acaagaaggt
     1081 gcattaggta agaaagttga aatcgtcaga atattttctg taaacaatga agaagtttca
     1141 cgagaaatta tttcaacttc aacgactgcg cctgtttcaa gaatagtcga aaaaggtact
     1201 aaaaaagctc aagttataaa ggaacaagct gagactggtg cagaacataa ggaagtacag
     1261 tctggagcta ttgttgaacc cgcaattcag cctgaactac cagcagctgt attaaccgac
     1321 aaaggtgagt cagcagtcca accagagttg ccagaagctg tagtaagtga taaaggcgta
     1381 ccagaagttc aaccagcgtt accagaggca gtcatgactg acaagggtga tccagagcag
     1441 gtagaaccgc taccagaata tacaggagta caagctggag ctattgttga acctgaaaaa
     1501 gttgaaccgg aatatgctgg agtacaagct ggcgctattg ttgaaccaga gcaggtagca
     1561 ccactaccag aatacacagg ggtgcaagcc ggagcgatag tcgagccaga gaaagtagaa
     1621 gcaccgaagg aatacacagg agtgcaggct ggagcgatag tcgagccaga gaaagtagaa
     1681 gcactgaaag aatatactgg taaaatcgaa caacctagtg cagaagatac taaaccaaat
     1741 aatgaaaata ctaatacacc agaagaaatg agtattcaga aaaaatctag tgcattaatt
     1801 aatatgaact ttattacaga ttcgtcgaag gttactggag taggatcagc tacttttatt
     1861 gcaccaaatg tacttttaac agtagcacat aatttcatta ataattctac tgataatact
     1921 actggcgaat ttagaggtga taaatctaaa aacgtatatg agtgggtgac tcctgatgga
     1981 caaaaaggaa catttactgc taacaatatt catttttata ataaaaaaga ttatccaaaa
     2041 ggatttatct atgatttagc agtgattaag ctacctgaaa caactggcag agaacatgta
     2101 gaattagtta aaaattattc gaaagtaaat cttaatgaca aactaaatgt tcatggatat
     2161 ccagctggga aatatacgca cttaaaagat gctacggtag aaatggaaca agaatatgcg
     2221 aataacacct acggtgttca atatcaaggt ggaaatcctg gtatgagtgg tggaggaata
     2281 tttaatgcta atggtgaagt tattggtgtg catcaaaatg gagcacaaaa tcgctcaggc
     2341 ggattgattt tatctcctac acaattagct tggattaaga gtattatagc aggtaatgaa
     2401 attccaccag tatacgatga actttatcgt cataaagatg agaaaaaaga tgacgctaaa
     2461 gatgaaaaag aagttattaa gaaattagaa cttagaaata tatcttctgt agaactatat
     2521 tcaaaagatg gtaataagta tcgacatgta acttcacttg cttctttacc aagtaatgca
     2581 gaaaattact ttatgaaagt taaatcagag aactttaaag atgtgatgct accagttaca
     2641 agcattacta atgatactaa agataataga gatgtttata agatagtagc aagtgcaaat
     2701 agtctgatac aacatgaaaa taataatgta ctagaaaatt atacatacta tttaccaaaa
     2761 actcagcaaa gtgaaactgg ggtatataca tcatttaaaa atttagtaga tgcaatgaat
     2821 agcaatccta atggcacatt ccgtttagga gcaactatgg atgctcgtga agttgaactt
     2881 ccagatggtc aagaaagtta tgtgaataat gtattccatg gaatattagt aggaacaaat
     2941 aatgagaaat attatgctat ttataatttg aaaaaaccat tatttgggga attaaatggt
     3001 gctacagtag aaaaactttc actaaaagat gttaatattt ccgcaaagga cgatactgca
     3061 acacttgcga aagaagcaaa taacaatact catattgata acgttcatgc tgatggagcg
     3121 atagctgggg aacgtagcat aggaggatta gtatcacaag ttaataattc tactatttct
     3181 aacagtagct atacaggtag aataactaat acatataaaa cagttgctag ttatcaaatc
     3241 ggaggtttag taggcaaact ttctggtccg aggggattaa tagataagtc gttcgcatca
     3301 atcgatttat cttcaaatgc aacacaagga gaccagtcta ttggtggaat agttggtgca
     3361 gtagaaaata gtgcgcttat tagtaatagt tatgctgaag gaaatctaaa taatgttcaa
     3421 cgttttgcaa acgttggtgg agtagttggt aatctttggg atccggttgg aggattagaa
     3481 aaatccggtc gactttctaa tgtactaagc gatgttaatg taacgaatgg taatgctatt
     3541 gcaggttata attttaatgg tataaaagca aatggcacat acagtaataa aaataataag
     3601 gttgtgaacg tagtacaaga agatgatgaa atcttaacta aggattctac tgttcaaaga
     3661 ggagaagtat tagaagatgc acaaataaaa gagaaaaaag ctacttttgt atctaaaaat
     3721 actattaaaa cagaagattt taatttctct tc
//
LOCUS       DAVLCS010000082         3487 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLCS010000082 DAVLCS010000000
VERSION     DAVLCS010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3487
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.082"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            805..2964
                     /gene="pfbA"
                     /locus_tag="VXC78_002050"
     CDS             805..2964
                     /gene="pfbA"
                     /locus_tag="VXC78_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV0584045.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTIKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNGNGKETVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNIQINDKIDNKQDNKTEEVNHKIVGDGIETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGISLLLTLKGLKYYGKDK"
     gene            3123..3239
                     /locus_tag="VXC78_002051"
                     /pseudo
     CDS             3123..3239
                     /locus_tag="VXC78_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828859.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase 2C family protein"
BASE COUNT         1330 a          439 c          638 g         1080 t
ORIGIN      
        1 aatattgttc aaagttttgt gcctgtcttt catgttctag tcattctttt gcatgataga
       61 atttatagca tattgatatt ataataatac aaatattcta tacgtttagt gatgcttgct
      121 atacatcatt agatctcccg cgagacaatc tataaaacac ttgtctacga ttacctatat
      181 gccctattcc agtattttag aagcactgca tctattttta tcgaggttaa atctagcttt
      241 tatagaaggt ctatttaaga aatatattgt agtgttttag tttcaatccg ccatatgagc
      301 gatattcagg taaatatccc tagcgaatgc ttgtatgaca agatatttgt tctttcattt
      361 ataatttaca acatatcaac aaatttaaat atagtaaatg ggatatttta tattcaagct
      421 aagaaagata gcatcacttt tgaatggaag gctaaagagc aaactaggaa gttggccata
      481 gatagctcaa aaccctgctt tgaggttgta gatataataa aatgaaataa gaataggaca
      541 aatcgatcgg gacagtcaaa tcgatttcta acaatgtttt agaagtagag gtgtactatt
      601 atagtttcag tctactatag aactgaccaa gtcagtaacc tagacttagg gcaaggcggc
      661 actgacctag tttgaagaga tttccgaaga gtataaattt taatattttc ttgtgttatt
      721 ccttgacaat tcaatttgga aaatatatga taaagataat gacagcggtg tcattctatc
      781 tattttaaga aaagtaataa tcaattgtta aaaatagtaa aaaaattgga ggttctgatg
      841 aaatattttg ttcctaatga ggtattcagt attcgtaaat taaaggtggg gacttgctcg
      901 gtactattgg caatttcaat tttgggaagc caaggtattt tatcggatga agttgttact
      961 agttcttcac cgatggctac aaaagagtct tctaatgcaa ttactaatga tttagataat
     1021 tcaccaactg ttaatcagaa tcgttctgct gaaatgattg cctctaattc aaccactaat
     1081 ggtttagata attcgttaag tgttaatagt atcagctcta atggtactat tcgttccaat
     1141 tcacaattag acaacagaac agttgaatct acagtaacat ctactaatga aaataagagt
     1201 tataaggaag atgttataag tgacagaatt atcaaaaaag aatttgaaga tactgcttta
     1261 agtgtaaaag attatggtgc agtaggtgat gggattcatg atgatcgaca agcaattcaa
     1321 gatgcaatag atgctgcagc tcaagggcta ggtggaggaa atgtatattt tccggaagga
     1381 acttatttag taaaagaaat tgttttttta aaaagtcata cacacttaga attgaatgag
     1441 aaagctacca ttctaaatgg tataaatatt aagaatcacc cttctattgt ttttatgaca
     1501 ggtttattta cggatgatgg tgcgcaagta gaatggggcc caacagaaga tattagttat
     1561 tctggtggta ctattgatat gaacggtgct ttgaatgaag aaggaactaa agcaaaaaat
     1621 ctaccactta taaattcttc aggtgcattt gctattggga attcaaataa cgtaactata
     1681 aaaaatgtaa cattcaagga tagttatcaa gggcatgcta ttcaaattgc aggttcgaaa
     1741 aatgtattag ttgataattc tcgttttctt gggcaagcct tacccaaaac gataaaggat
     1801 gggcaaatca taagtaagga gagcattcag attgaaccat taactagaaa aggttttcct
     1861 tatgccttga atgatgatgg gaaaaaatct gaaaatgtga ctattcaaaa ttcctatttt
     1921 ggcaaaagtg ataaatctgg ggaattagta acagcaattg gcacacacta tcaaacattg
     1981 tcgacacaga acccctctaa tattaaaatt ttaaataatc attttgataa catgatgtat
     2041 gcaggtgtac gttttacagg attcactgat gtattaatca aaggaaatcg ctttgataag
     2101 aaagttaaag gagagagtgt acattatcga gaaagcggag cagctttagt aaatgcttat
     2161 agctataaaa acactaaaga cctattagat ttaaataaac aggtggttat cgccgaaaat
     2221 atatttaata ttgccgatcc taaaacaaaa gcgatacgag ttgcaaaaga tagtgcagaa
     2281 tatttaggaa aagtatcaga tattactgta acaaaaaatg taattaataa taattctaag
     2341 gaaacagaac aaccaaatat tgaattatta cgagttagtg ataatttagt agtctcagag
     2401 aatagtatat tcggtggtaa agaaggaatt gttattgagg attcaaaggg taaaataacc
     2461 gttttaaata accaatttta taatttatcc ggtaagtata tatcattcat caaatctaat
     2521 ggaaatggga aagaaactgt tatacgtgat agcgatggta atttcaatat tgtaacggag
     2581 aatgggcttt acaaaattgt aacaaataat ttaagtgata aaaacgaaaa agaaaaaaac
     2641 aaagaggaaa aacaatctaa ttcaaataat gtaattgata gtaaccagaa gaacggagag
     2701 tttaactcaa gtaaagataa tatacaaatt aatgacaaga tcgacaataa acaagataat
     2761 aagacagaag aagtgaacca taaaatagtt ggagatggca tagaaactga aaatcatatt
     2821 aataaatcta aagaaatagt agatgtaaaa caaaaattac caaagactgg ttcgaacaag
     2881 attatggaac tattcttaac agtgacagga attagtttac ttttgacact aaaagggttg
     2941 aagtattatg gtaaagataa ataaaatttg ttcgatacaa ggaagttctg tagaaaatga
     3001 ggatactgta ggttcacaaa atcagtattt ttggattatt gatggagcta cagatttata
     3061 taattctaaa gaaggagata ggttattcag tctcagaagt tgtacatatt ttatcagaaa
     3121 gtttgtcggt taattgtaaa gaatcaaaaa ctcttaaaca aatatttgaa actgctttac
     3181 tcgaggttaa agatgaaatc ggtttaaact catatgaatt aacagagtat tatcgcttac
     3241 caacatttgc ttttatattt gctaaacttt cagaaaaaaa gttggagtat atgatgctag
     3301 gtgactgcgt catgttagta aacgaaatgg aaataactga tcatagagta gataacttat
     3361 ttgaaaaagg gaaaaatgag ataaaagact caattggtac aaatagtgtt ttaaataaaa
     3421 aaattatttt acaaaaaatc agaaaattat ctaatcaacc gagtgggtac tggataggtt
     3481 cgttgga
//
LOCUS       DAVLCS010000083         3074 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLCS010000083 DAVLCS010000000
VERSION     DAVLCS010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.083"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(285..818)
                     /locus_tag="VXC78_002052"
     CDS             complement(285..818)
                     /locus_tag="VXC78_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV0584046.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(907..1683)
                     /gene="recX"
                     /locus_tag="VXC78_002053"
     CDS             complement(907..1683)
                     /gene="recX"
                     /locus_tag="VXC78_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV0584047.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLSQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1721..>3074
                     /gene="rlmD"
                     /locus_tag="VXC78_002054"
     CDS             1721..>3074
                     /gene="rlmD"
                     /locus_tag="VXC78_002054"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0584048.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT          972 a          541 c          553 g         1008 t
ORIGIN      
        1 aaaatgtttt tgatacgaag ttgacctgta ttttttatac taatcatttt cgtatttttt
       61 gtattaaacg atataagttt gttgtaaact tactaggaat aaagacatta aaaaataata
      121 gtatatctat ttgttttata tattttacga attctgcata aatctctttc tagtaatgtg
      181 ttgtaactct gctataatgg atttattcct ttttgtattt acacaattta ttttatacta
      241 ccaaaaaaac aaggtcagga ttttgttcct gacctttgac aactttaccg attctttagt
      301 tctacatagc gcttgtacca aatgtttaca taggcttctg agaaaggacc acgtccattg
      361 ttaatccaat caacaagaat tttgacatgt tcttttaaaa tatagtccaa gtcatcagaa
      421 taattcattt tgcgtttgtg acgctcgtat tcttcaacgt ccaagagacg tttttcccca
      481 tctgtaaaaa ttttaacatc caaatcgtaa tcaatatact tcagtgcttc ttcatccaga
      541 tagtaggggc tagccatatt gcaatagtaa gaagttccat tatcacgaat catggcaatg
      601 atattaaacc aatatttctt gtgaaagtaa acaatagccg gttctcgagt gacccaacga
      661 cgaccatcac tttcggtaac aagtgtatga tcgttgacac caataatggc gttttctgtt
      721 gtttttagta ccatggtgtc ccgccaagtt cggtggagac tcccatcatg cttataactt
      781 tgaattgtaa taaagtcgcc ttcttttgga agcttcataa ctaaccaact ttctacaatt
      841 tataagttta tcatttacta ttgtaccata aaattaccta aaatctgtga atttcacttg
      901 gaaatattaa agatattctc taagagcgct tgctatatcc gaaaaatcgt agccctttcg
      961 tgctaaaact tgagttaaac gctgcttcag ttcgtatcct tcatactttc gagcatactt
     1021 agtatattgc ttatcaagtt ccttgaagat gagttcttga gtcgtttctt ggtcaacttg
     1081 gctatctaag tcgtcaaagg caattttagc atcagaataa gagaagccct tgttagtcaa
     1141 gttctggata atcttatctt gcagggcacg agctggaagt tttccctcat attttttcaa
     1201 tagtttattg gctacacgtt gagcaacttc agaaaaatca aattctttca agttctcttc
     1261 tatagtagat tttgaaatcc ctttttgaga tagtttctga gtcagcacat aaggaccctt
     1321 gtctcctgaa agttgattgg tattgatgat agcataagcg tactgaccat cattaatcca
     1381 cttatcttct ttaagattag caataacttg agaaacgatg tttttatcaa tatcgtattt
     1441 tttcagatat tctctgactt ctttttcagt gcgtgcttta aaggataagt ggtagagagc
     1501 gagattctta ccataagaaa attgagcaaa gtcttgaatc tctttcaatt cctcttcgct
     1561 tatcacctta tctctcgata acataaaacg aacaattgta tcttcggtga tatagcattt
     1621 gtcgccatta tcaagctcca tcaggtagag tctttttttc ttttcaagtt ttgtgatttt
     1681 catagctcta ttataactca aaatgtgata agataggggt atgaatctga aagtgaaaca
     1741 aaaaatacca ttaaaaatca agcgcatggg aattaacggt gagggaatcg gcttttacca
     1801 aaaaacatta gtctttgtac caggagctct caaaggcgaa gatatctatt gtcagattac
     1861 ttctattaga cgcaactttg ttgaagcaaa attactgaag gtcaacaaga agtctaaatt
     1921 tcgaattgtg ccatcttgta ctatttataa tgaatgcgga ggctgccaaa tcatgcacct
     1981 gcattatgat aagcagctgg agttcaagac ggacttactt catcaagcgc tgaaaaaatt
     2041 tgctcctgca ggatatgaaa attatgaaat tcgtccaact attggaatgc aggaaccaaa
     2101 atattacaga gctaagttac aatttcagac tcgaaaattt aaaaatcagg tcaaggcggg
     2161 cttatatgca caaaactctc actatttagt agagttgaaa gactgcctgg tacaagataa
     2221 ggaaacccaa gtgattgcta atcgcttagc agaattactt acttatcacc agattccaat
     2281 cacggatgag agaaaagttc taggtgtccg tactattatg gtccgacgcg cgagaaagac
     2341 cggacaggtt cagattatta ttgttacaaa ccgccagctt aatttaactc aattggtaaa
     2401 agagttggtt aaagatttcc cagaagttgt gacagtagct gttaatacaa atacagctaa
     2461 aaccagtgag atatatggtg aaaagacaga gattatctgg gggcaagaga gtattcaaga
     2521 aggtgtactc aattatgaat tttcactatc ccctcgagct ttttatcaac taaatcctga
     2581 gcaaacagaa gtcctctata gcgaagcagt aaaagcgctg gatgttgata aagaagacca
     2641 tttgattgac gcttattgtg gagttggaac gattggattt gcctttgcaa agaaagttaa
     2701 aacactcaga ggtatggata ttattccaga agctattgaa gatgccaagc gaaatgctaa
     2761 aagaatggga tttgacaata ctcattatga agctggaacg gcagaagaga ttattcctcg
     2821 ttggtacaag gaaggctacc gagcagatgc tttgattgtt gacccaccac gtacaggtct
     2881 ggatgataag ttattagata ctattcttac ttatgtacca gaaaaaatgg tttatatttc
     2941 ttgtaatgtt tcgaccttgg ctcgtgattt ggtacgctta gtagaagtct atgatcttca
     3001 ttatatccag tcggtcgata tgttcccaca tacagctcga actgaagctg ttgtaaaatt
     3061 aataaaaaaa gttt
//
LOCUS       DAVLCS010000084         3061 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLCS010000084 DAVLCS010000000
VERSION     DAVLCS010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3061
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.084"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            <1..582
                     /locus_tag="VXC78_002055"
     CDS             <1..582
                     /locus_tag="VXC78_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0584049.1"
                     /translation="LNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGD
                     DIKKTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFP
                     NNILDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKIL
                     DREDLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            931..1359
                     /locus_tag="VXC78_002056"
     CDS             931..1359
                     /locus_tag="VXC78_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584050.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPSTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            1371..2120
                     /locus_tag="VXC78_002057"
     CDS             1371..2120
                     /locus_tag="VXC78_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV0584051.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            2133..3061
                     /locus_tag="VXC78_002058"
                     /pseudo
     CDS             2133..3061
                     /locus_tag="VXC78_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
BASE COUNT         1100 a          332 c          567 g         1062 t
ORIGIN      
        1 ttaaattttt gttttcaacg taatgaaaag tatttaattt taggtgaaag tggaagcggg
       61 aaatctacat tattaaaatt attgaatggc tttttgagag attatagtgg agaattgcga
      121 ttctgcgggg atgatataaa aaaaacctcc tatttaaata tggtttcgaa tgttctatat
      181 gtagatcaaa aagcttattt gtttgaaggt acgattagag ataatatttt attggaagaa
      241 aattatactg atgaagaaat actacagtct ttagagcaag ttggtttgag tgtaaaagat
      301 tttcctaata acattttaga ttattatgtt ggtgatgatg ggagattact gtcaggaggg
      361 cagaaacaaa aaattacttt agctagaggg ctaattagaa ataagaaaat agtattaatt
      421 gacgagggaa cttctgctat cgataggaga acttcgttag cgattgaacg taagatatta
      481 gatagagagg atttgactgt cattattgtt acccatgctc cgcatccgga acttaaacaa
      541 tattttacta agatatatca atttccaaag gattttattt aagaatatag gggagggaaa
      601 catgagattc tattgtgaag cttatgaggt aattactgaa gagaaaaaag tatactttaa
      661 tgatattgag ttagaagtta agtattcctc tgtcgaagaa ttgtttataa tatgtgagaa
      721 attattagat aagaaaaaag tatcattttt ttatgtagat gagaaaccct taaggtatct
      781 gttatttgac tatatatttc tactagttct agctaaaaaa atatcccaat cttatgaact
      841 gcaccccaaa agttagattt attctgtcta acttttgggg tgcagttcat tttgcatagt
      901 tttggcattc atcctagata tccatataaa atgtctgaga ttgttgaaat gtctaaaaaa
      961 atatcagatc taaacgataa aaaagaattt cacaaaaaga actgtgagtt gaggtttcaa
     1021 gatagtgttc ttgataacat aaatagtgtc ccgagtacaa ctcatttatt tagttgttta
     1081 aatattcaaa cattagtaaa aattatttta tatatttttc gatacaacag ttgtatgaaa
     1141 atatttaatt ttagagataa agagcttatc ttttttaata agattgtaaa tgggctgata
     1201 caaaatattg aggagaattt agaggatgat attgaaagga tattgaaata tttatatata
     1261 tgtttattta acgaaatatt cattattaag aataaggtga atttttttga tgatgtggaa
     1321 tttaatcaga cacttagtga gtttttagat aaattgtaga gggaatggtt atgagtaaca
     1381 atactaagta tatcttttta tctccacatt tagatgacgc aattttttcc tgtggtgatt
     1441 atatttcaaa attaacttca gaaggagaaa ttgtacttgt tattactata ttttctggtt
     1501 accctttgag ccaacagcta cagccctctg ctaagcaatt tcataagttg tgtaaccttg
     1561 ggaaatatcc gattgaagaa aggaagaaag aagacaggtt agcttgtgaa cgtctacagt
     1621 gtgattttag acacttatcg tactatgaat gtctctatag gaaagataga aatggcaatt
     1681 ttctataccg tcatatctat agtgaattaa aaaatgagga cacattaaag aatgatatca
     1741 taaaagagct gttaatgcat ttagacgaca aatgtgtcgt atattgtccg ctttcacttg
     1801 gtgaccatgt tgatcatgtt tttgtgaata gtattggaag ggcgcttgaa tttatgcgtt
     1861 ataaagtaat atattatgag gacttcccat atgtaagtga tagtagtatg gttagttata
     1921 tgggaaaaac taaagaatta aaaatgtatc aagaggaact tgatgaaaaa cattatattg
     1981 atagaatatc atcaatattg tgctataaat ctcagatttt gataatctgg aaatcagttg
     2041 aaaaactttt aaacaatatt aaagagttgt atttaaggaa tggggcagct tattctatta
     2101 gattttggat taagaaataa ggaagtagtt ttatgaatat agcagtaatt ggtttggggc
     2161 atgttgggct ggcctacgcg ttactatttg catctaaata taaagttgtt gcatatgata
     2221 tagattctgt aaaaataaat aatttaaaaa agggcattct tccatctaaa aatgaagagc
     2281 ttatgaagtt tttttgcgag aataacttaa atattacttt ttttgataca ttttctgaaa
     2341 ttaaaaataa tattgattat tatattattg cgcttccgac agattatgat gagaaaattg
     2401 gtagttttaa tacatatgaa atcgaacaaa cggtatcgaa gattctgagg gtaaaaccta
     2461 atggaaagat tattttaaag tcaacagttc cgttcggctt ttcaaacaaa ttaaaaaggc
     2521 tgtttgatac aaaaaatatc atttttgtcc ctgaattttt gagagaaggt tgttctatat
     2581 atgataattt atatccaagt cgcatagttg ttggagatga gacagttgaa ggaagaaaaa
     2641 ttgcagagtt gttcctttcg attagtactc atagtactgc caatattaaa aatgttatgt
     2701 tagtttctcc tactgaagca gaagcaatta agcttttttc taacacattc ttagctctcc
     2761 gtgttgcttt ttttaatgaa ctagattctt ttgctgagag gagaagttta aatgctgaag
     2821 ttgtaataaa aggtgtttgt ttagatccaa gaattggaaa tttttataat aatctttctt
     2881 ttggatttgg aggatattgt cttcccaaag atactaaaca ataaaaaaaa gaatttatag
     2941 aaataaatgc cccagtgata gaagcgattg atatttcaaa cacaaataga aaacagttca
     3001 tagttaaaca aatattggaa cgaaagccaa agatagtagg aatatataaa ttggggatga
     3061 a
//
LOCUS       DAVLCS010000085         2813 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLCS010000085 DAVLCS010000000
VERSION     DAVLCS010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2813
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.085"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(<1..382)
                     /locus_tag="VXC78_002059"
     CDS             complement(<1..382)
                     /locus_tag="VXC78_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584052.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKY"
     gene            complement(396..1109)
                     /locus_tag="VXC78_002060"
     CDS             complement(396..1109)
                     /locus_tag="VXC78_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV0584053.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1569..1949)
                     /locus_tag="VXC78_002061"
     CDS             complement(1569..1949)
                     /locus_tag="VXC78_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV0584054.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            complement(2366..>2813)
                     /locus_tag="VXC78_002062"
     CDS             complement(2366..>2813)
                     /locus_tag="VXC78_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV0584055.1"
                     /translation="RNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEPTHPESDE
                     KENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEK
                     VTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDSLLALLKESK"
BASE COUNT          873 a          558 c          438 g          944 t
ORIGIN      
        1 catattttgc tacatgatct aggtatatat caaaaaagtc atgaggaaaa tctcccatac
       61 agccattacg attcatattg aggctatatt ttcgattagt aagataattc ggaaatatat
      121 ttcctattac tctaagatta tctacttgtg aatcccttct cccaatataa tccccttctt
      181 tgactaatga tggagatttc caagtaaaaa ttaaatcgcc agagaaattt ttcttatcaa
      241 aaaacttaaa aagagattga taaatactat ttgctaattg acaagtgtca gatgtaaatt
      301 cataattaac agcttcatta aaatcaactt cagacatttc aatgtactct tcaatagtaa
      361 tattagcttt ttttgtagtc attagctaat ctcctttaaa atgtgatctt ttcaagaata
      421 tttttatcta aacaatccag caagtcttgg taagaataga cttcgtaagt cggctgggct
      481 tgtgtgtgat tttcgaggtg atgaggatta taccagatag tgtcaatccc cgcattattg
      541 ccaccttgaa tgtcggcggt tagagaatct ccaatcatca gcgtcttttc tttactaaat
      601 ccagcaattt gctggccaat cttttcataa aagagagcat ccggcttttg agtttgcaac
      661 tgttctgaga taaagacttg attgaaataa ggtgctagac cagattgagc caaacgtcct
      721 gtctgaatgg cagtaatgcc atttgtcgca gcatacaagt cataatcacg ctcaatgagg
      781 ctgtccaaga gatcatgagc gcccgatagt gtttgtccct gctgggcgag gtaaaattgg
      841 taacgctggg caagaaaact accgtctttt tcctgtccaa aatgagaaaa taaacgagaa
      901 aagcgcgtgt taaccagctc ttgtttactg attttcttca gctccaagtc tttccagaga
      961 gccttgttca taggaacgta ataatcttta taagcctgaa tatccgcaac tccttcttct
     1021 tttagaagtt gggtcaaagc cacatcctca gcagcatcaa aatcaagaag agtgtggtcg
     1081 aggtcgaaga gtagaaattt gtagaacaat ttgaggtttt cctttctgaa aattcattaa
     1141 gaacattata tcataaagca cctcatacaa ttaactaatt taatcactta aaaaaaattc
     1201 gaacactttc tatacaactg acagctcaaa tctttcagaa tagaacaata ctaactatcg
     1261 agcacccccg tcttcataaa tatatgtgta attctagacc tagaattcct ataaactaaa
     1321 tgctttcata ctcttccaag taattgattg ccttaaattt taatttttga aggattctaa
     1381 agctagaata gccccatcac aatcagtttt gattgattca caatttagaa acactatagt
     1441 ttcactcctg ttaaaataaa aaggaactgc ataaagcaat ccctttctaa ttttgaaatc
     1501 atttacttaa cattttatag ttgagataat caatagctta cctataaaaa gagttatagt
     1561 aaaattcctt atttattgat ttcaagctcc gctaactgtg tttgaataac tgacagttct
     1621 gcaccagcct gcagaagagc agctgcatta taggcacctt ctacaattgg aaccctgttg
     1681 atgatgatac ttttatcact gaaatcagtc accattttta agttcatttt agcagaacct
     1741 aggtcaaaaa aggcaagtaa agtatctgct ggattttcgg aaacaaccct atctacttga
     1801 tcaaaactcg ttccaattcc tccgccctcg gttcctccta cataagtaat cggaacatct
     1861 ttagctactt tactaatcag ttcaacaaca ccttctgcaa tgtgtttgga atgtgaaacg
     1921 ataacaagac caataccaat actttccatc aaaccacccc agtttctaaa atagcagtaa
     1981 agagtaatcc tgatgagaat gatccaggat caatatgtcc aagaaaccat atgctcctaa
     2041 gacaagagcc aacagactgg tcatcaataa tagtattgtt ctttttttca tcattactcc
     2101 ttaactagtg tttaactgat taattagcca gtaaatagtt tatctttatt tacactatct
     2161 gttaagatat agtaaaataa gaacaggaca gtcaaatcga tttctaacaa tgttttagaa
     2221 gtagaggtat actattctag tttcaatcta ctatattttg cacattttca tgaaaaaaat
     2281 gagaactaga actcacattc tgctctcatt tttcgttttc ccgttctcct atcctgtttt
     2341 taggagttag aaaatgctgc tacctttact tactctcctt taataaagcc aagagactat
     2401 ctacttctgc tgaaatagtg ttattatctt tcgttccgag aagaagacta ctttttagac
     2461 cagtcaatgt ctccacagca ttttgtctaa tactagaatc tgttactttt tctagcaagg
     2521 cctccgcatc tgctatctta gcgttaataa cagaatgctc tacttgagga atttcagcct
     2581 catctgtagt atcttcagct tcttcctctg tctcttccgt atcagtgctt ggtttataaa
     2641 gattatctgc tgaaggattt aaaccagcgt gattctcttt ttcatcagat tcagggtgag
     2701 ttggctcact tacttcatca tgttccttat cttcctcagg tttttctgtc tgaggtttct
     2761 cctcgtttgg tttttccgtt tgattggtat cagcttgacc atttttgttt ctt
//
LOCUS       DAVLCS010000086         2481 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLCS010000086 DAVLCS010000000
VERSION     DAVLCS010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.086"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            144..1340
                     /gene="tuf"
                     /locus_tag="VXC78_002063"
     CDS             144..1340
                     /gene="tuf"
                     /locus_tag="VXC78_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0584056.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(1449..2481)
                     /locus_tag="VXC78_002064"
                     /pseudo
     CDS             complement(1449..2481)
                     /locus_tag="VXC78_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          769 a          475 c          518 g          719 t
ORIGIN      
        1 ttaaattttt accaagaata attcacaaaa acgttgtaaa acacttgcaa tttagctgaa
       61 atttgataaa atagtaagga aagttagact gtattgccta ctgtctatct ataaaatata
      121 ttttattgga ggcttttact caaatggcaa aagaaaaata cgatcgtagt aaaccacacg
      181 ttaacattgg tactatcgga cacgttgacc acggtaaaac taccctaact gcagctatca
      241 caactgtttt ggcacgtcgc ttgccttcat cagttaacca acctaaagac tatgcgtcta
      301 tcgatgctgc tccagaagaa cgcgaacgcg gtatcactat caacactgcg cacgttgagt
      361 acgaaactga aaaacgtcac tacgctcaca tcgacgctcc aggacacgcg gactacgtta
      421 aaaacatgat cactggtgct gctcaaatgg acggagctat ccttgtagta gcttcaactg
      481 acggaccaat gccacaaact cgtgagcaca tccttctttc acgtcaggtt ggtgttaaac
      541 accttatcgt cttcatgaac aaagttgact tggttgacga cgaagaattg cttgaattgg
      601 ttgaaatgga aatccgtgac ctattgtcag aatacgactt cccaggtgac gatcttccag
      661 ttatccaagg ttcagcactt aaagctcttg aaggtgactc taaatacgaa gacatcgtta
      721 tggaattgat gaacacagtt gatgagtata tcccagaacc agaacgtgac actgacaaac
      781 cattgcttct tccagtcgag gacgtattct caatcactgg acgtggtaca gttgcttcag
      841 gacgtatcga ccgtggtatc gttaaagtca acgacgaaat cgaaatcgtt ggtatcaaag
      901 aagaaactca aaaagcagtt gttactggtg ttgaaatgtt ccgtaaacaa cttgacgaag
      961 gtcttgctgg agataacgta ggtgtccttc ttcgtggtgt tcaacgtgat gaaatcgaac
     1021 gtggacaagt tatcgctaaa ccaggttcaa tcaatccaca cactaaattc aaaggtgaag
     1081 tctacatcct tactaaagaa gaaggtggac gtcacactcc attcttcaac aactaccgtc
     1141 cacaattcta cttccgtact actgacgtta caggttcaat cgaacttcca gcaggtactg
     1201 aaatggtaat gcctggtgat aacgtgacaa tcgacgttga gttgattcat ccaatcgccg
     1261 tagaacaagg tactacattc tctatccgtg agggtggacg tactgttggt tcaggtatgg
     1321 ttacagaaat cgaagcttaa ttcgatttag ttcccagaag aacaattatt taagtcagac
     1381 actaaaagaa tcttgcttgg caaggttctt ttttggctct ttgtcaactg tagtgggttg
     1441 aaaaaaaact aagctcgaga aaggacaaat ttcgtccttt cttttttgat gttcagggcg
     1501 atgaaaatcc gttttttgaa gttttcaaag ttccgaaaac caaaggcatt gcgcttgata
     1561 agtttgatga gattattggt cgcttccaat ttggcgtttg aatagggtag ttgaagggcg
     1621 ttgacgattt tctttttgtc ctttagaaag gttttaaaga cagtctgaaa aagaggatga
     1681 acctgcttaa gattgtcctc aatgagtccg aaaaatttct ccggttcctt attctgaaag
     1741 tgaaacagca agagttgata gagctgatag tggtgtttca agtcttccga ataactcaaa
     1801 agcttgttta aaatctcttt attggttaag tgcatacgaa aagtaggacg ataaaatcgc
     1861 ttatcactca gtttacgact atcctgttgt atgagcttcc agtagcgctt gatagccttg
     1921 tattcatgag actttcgatg aaactgattc atgatttgga cacgcacacg actcatagta
     1981 cggctaagat gttgtacaat gtgaaagcga tccaacacga ttttagcatt cgggagtgaa
     2041 acagtctggg agactgtttc agcctgagcc tagaaatttg aaagcgaagc tgtttagcta
     2101 agtcatagta aggactaaac atatccatag taataatttt gacgcgacat cggacggctc
     2161 tatcatattt aagaaagtga tttcgaatga tagcttgtgt tcttccctca agaacagtga
     2221 tgatattgag attgttaaaa tcttgcgcaa tgaagctcat ctttcccttt gtaaaagcat
     2281 actcatccca agacataatc tcaggaagac aagaaaaatc atgtttaaag tgaaagtcat
     2341 tgagcttacg aataacagtt gaagttgaga tggaaagctg atgggcaata tcagtcatag
     2401 aaatcttttc aattaacttt tgagcaatct tttggttgat gatacgaggg atttggtgat
     2461 tcttcttgac gatagaagtt t
//
LOCUS       DAVLCS010000087         2456 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLCS010000087 DAVLCS010000000
VERSION     DAVLCS010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2456
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.087"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            111..275
                     /locus_tag="VXC78_002065"
     CDS             111..275
                     /locus_tag="VXC78_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0584057.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAEMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            359..925
                     /gene="amaP"
                     /locus_tag="VXC78_002066"
     CDS             359..925
                     /gene="amaP"
                     /locus_tag="VXC78_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV0584058.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            937..1107
                     /locus_tag="VXC78_002067"
     CDS             937..1107
                     /locus_tag="VXC78_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV0584059.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1146..1754
                     /locus_tag="VXC78_002068"
     CDS             1146..1754
                     /locus_tag="VXC78_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0584060.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1785..1988
                     /locus_tag="VXC78_002069"
     CDS             1785..1988
                     /locus_tag="VXC78_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0584061.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2099..2371)
                     /locus_tag="VXC78_002070"
                     /pseudo
     CDS             complement(2099..2371)
                     /locus_tag="VXC78_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          852 a          370 c          472 g          762 t
ORIGIN      
        1 ttgatttttt gatattaaaa taaaaaagga gggtaggcag tgttgtgatc aattattgct
       61 ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa aagtagttct atgggaatca
      121 tcgcaaatgt attcgctggt ttagtcgggg catatgcagg acaatctctt ttaggtagtt
      181 ggggtccatc aatcgctgaa atggctttgc tcccatctat tgtaggtgca gcgattgtga
      241 ttactgtagt gtcattcttt acaggtagaa agtaaacttt tcgccagtaa agttagcaaa
      301 ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt aaatcgaaag gattgtatat
      361 gtcaaaagca aagaaaatat gtttcattat tttctgtatt ttaatcttga caattttcct
      421 tcctgttttg atagattatc atcaagttag tgatctaggt attcatctac ttagctggag
      481 acagaactcc gtagttgaat tctatcttgc tagatatgtc ttttggggga cagtggttct
      541 atcaacttta gttttattat ccattttagt tgtgatgttt tatcctaaac gttacttgga
      601 aatccaactt gaaactaaaa acgatacatt aaaattaaag aattcggcaa tcgaaggttt
      661 tgttagaagt ttggtgagtg atcatagatt gatcaagaac ccaactgttc atgtaaattt
      721 acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt cttccttcag acaacatcgc
      781 tgacagatgc caaataattc aaaatgaaat aactaatgga ttgaagcagt tttttggtat
      841 tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac caaccaaaac ctcaaaacaa
      901 aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg aatggcttaa acaatatcga
      961 tatccaatta tcgctggtct cataggcgta tttctggctt gtttgattgt ctcctttggc
     1021 ttcttcaaaa caatatttgt attgatttta ggagcactgg gagttgcagc tggattatat
     1081 atcgaaaaaa actatataga taaataaaaa aataaaaatt actaatttaa ttaaaggagt
     1141 ttcatatgtc aaacgaaaaa aacacaaaca ctaacgtaga aaagaaagat gctactgttg
     1201 tagctcacga aatcaaaggg gaacttactt acgaagataa agttatccaa aaaatcattg
     1261 gtctttcact agaaaacgtt tcaggtcttt tgggaatcga tggtggtttc ttctcaaatc
     1321 ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg tgttaacgta gaagttggta
     1381 aaacacaagt tgcagttgac ttaaacgtta ttgttgagta ccaaaaaaat gttccagctt
     1441 tatattcaga aatcagagaa atcgtatctt cagaagttgc taaaatgact gacttggaaa
     1501 ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa agaacagcat gaagcagact
     1561 cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc aacaggagaa ttcacttcag
     1621 aacaattcga aaaagctaaa tctggtcttg gatctggttt ctcaactgtt caagaaaaag
     1681 ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg tgtagtatct cacgaaaaca
     1741 ctcgtgtaaa ctaagataaa ataaatataa caggagaaat tatcatgtca gtagaagaaa
     1801 aattaaatca agctaaaggt tctattaaag aaggtgttgg gaaagccatc ggtgatgaaa
     1861 aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa agtaaaagaa gttgccgaag
     1921 acgctaaaga cgctgtagaa ggtgctgtag aaggtgttaa aaacatgttg agtggcgacg
     1981 ataaataagg ttaaaagtta ctttatcttt tttggtaaca ttagtcaaaa gagtctgagt
     2041 caagatgatt ctcagaaaac aaaaagctag agattcccaa ttgcggaact ctagcttttt
     2101 aattttgcct ctttctctta ttatatttca gcaggttgtt ggccatgagt atgaatccca
     2161 tgtcaattct cacttgacgc ttacctctca gatgacatct cttataaccc aaacaaacct
     2221 ttatctgccc aaagacagat ttcatatcaa tcttacgttt agcgaaaatt tgtctaccct
     2281 tggaagataa aagtgcctga tattctttag tttttaaaca ctggtaacgt tcattcatat
     2341 acagtccctt ttgaggggct gattcaggtt cataatcgca gtcaacattg atttcaaggc
     2401 tgtttgcttt ctatctcccc tttttcataa tgtatagtaa aatgaaataa taacag
//
LOCUS       DAVLCS010000088         2397 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLCS010000088 DAVLCS010000000
VERSION     DAVLCS010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.088"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            129..1625
                     /locus_tag="VXC78_002071"
     CDS             129..1625
                     /locus_tag="VXC78_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0584062.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRK
                     KDEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEE
                     ADKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAIIVP
                     DGVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDK
                     VWFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEN
                     DYDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1638..>2397
                     /locus_tag="VXC78_002072"
     CDS             1638..>2397
                     /locus_tag="VXC78_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0584063.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDI"
BASE COUNT          855 a          350 c          472 g          720 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga tcagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgtcga ccgcaggtaa aaatggacag ttccgtacac
      661 ctcgtcacat catcgatatg atggttgagt tgatgcaacc gactatcaaa gatatcatct
      721 cagatcccgc tatgggttct gctggcttct tagtatctgc tagccgttac ttaaagcgta
      781 agaaagatga atgggaaacc aatacagata atatcaatca ttttcataat cagatgtttc
      841 atggaaatga tacggatacg actatgttga gacttggggc gatgaacatg atgctacatg
      901 gagtagaaaa tccacaaatc agttaccttg actcgctgtc tcaagataat gaagaagccg
      961 ataaatatac tttggtttta gcaaatcctc cttttaaggg ctcacttgac tacaattcaa
     1021 cctctaatga ccttcttgca accgtaaaaa ccaaaaaaac agaattactc tttctttctc
     1081 ttttcttgcg aactttaaaa ccaggtggac gagcagcaat tatcgtacct gatggtgtcc
     1141 tttttggttc gtctaaagct cataaaggaa ttcgtcagga aattgtagag aatcataagc
     1201 ttgatgctgt aatctcaatg cctagtggtg tgttcaagcc ttatgctgga gtttcaactg
     1261 ccattctcat ctttacaaaa actggtaatg gtggtactga caaagtctgg ttttacgata
     1321 tgaaagcgga tggtttaagt ttggatgata agcgacaacc gattagcgac aatgatattc
     1381 cagatattat cgaacgcttt catcatcttg aaaaagaagc agaacgtcag agaacggatc
     1441 aatctttctt tgttccagtt gctgagataa aggaaaatga ttatgatttg tctatcaata
     1501 aatataaaga gattgagtat gaaaaagttg agtatgaacc aacagaggtc atcttaaaga
     1561 aaatcaatga tttagaaaaa gaaattcaag ctggcttggc tgaattagaa aaattactca
     1621 agtagggagg tggctgtatg aaaaaagtga agttggggga agtcttatct ctaaaaaaag
     1681 gcaagaaagc cactgtactt gctgaacaaa caactctaag ccaacgttat attcaaatag
     1741 atgatttaag aaataataat aatttaaaat tcactgaaag tttaaatatg actgaagcac
     1801 tcccagatga tattctgata gcatgggatg gagctaatgc aggaacagtt ggttatggat
     1861 tatcgggagc tgttggtagt acaattacgg tcttaaaaaa gaatgagcga tacaaagaaa
     1921 aaattatatc agattacttg ggagtctttt tggaaagtaa atcgcagtat ttacgagaac
     1981 attcaacagg tgcaacaatt cctcatttaa acaagaatat attacttgat ttacaattag
     2041 aattgctagg tatcgaagaa caagagaaca ttatctgtat tcttaatacg attaaagggc
     2101 ttattactaa aagaaaattg cagttagatg aactaaactt gctcgtcaaa tcccgattta
     2161 acgagatgtt tggggaaaat aaaatatttg aaagcattga taacttattt gatattatag
     2221 atggtgatag gggcaaaaat tatcctaaat cagatgagtt gtttagtgag gagtactgtt
     2281 tatttttaaa tacaaagaat gttactaaaa acggattttc attcgataca aagcaattta
     2341 tcactaaaac aaaggataaa ttacttcgaa aaggcaaact tgagcgttat gatatag
//
LOCUS       DAVLCS010000089         1825 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLCS010000089 DAVLCS010000000
VERSION     DAVLCS010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1825
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.089"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            336..977
                     /locus_tag="VXC78_002073"
     CDS             336..977
                     /locus_tag="VXC78_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0584064.1"
                     /translation="MTIEPGQRIALVGQSGSGKSTLSKILSGLYKIDTGKILFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKNEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIQS
                     QGCTQIIIAHRLSTIKDADIIFVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
     gene            990..1160
                     /locus_tag="VXC78_002074"
     CDS             990..1160
                     /locus_tag="VXC78_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584065.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYAISLGLLNGIV
                     LGSLIFYKNNKN"
     gene            1194..>1825
                     /locus_tag="VXC78_002075"
     CDS             1194..>1825
                     /locus_tag="VXC78_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0584066.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKV"
BASE COUNT          682 a          200 c          347 g          596 t
ORIGIN      
        1 attcagctac taatgtattt caattgttcg ctcctataat tatattgatt tttggacttg
       61 ataatgtttt aaatggaaaa attttattgg gtgaggttgt cgcatttcaa accatggcat
      121 caattttatt tagttcagaa atctcaatat ttaatgctta tacgcagtat attttggcag
      181 caggatactt aaatagagta aatgatatct ggcttgaaaa tgaagagaat gttgaaaatg
      241 gtcttaaaaa gtgttcttta gaaggtagaa tagatattaa ggacctatct ttctcttatt
      301 ccaaagactc agctcctgta atagaaaatt taaatttgac tattgagcca ggacagagaa
      361 ttgcactagt cggtcaatcg gggtcaggaa aaagtacgtt atcaaaaata ctatcaggat
      421 tatataagat tgatacagga aaaattttat ttgatggtgt aaatattaat caaatagata
      481 aaaaaatatt aagtcaaaat ttaggagtag ttccacagga ttcattttta ttgaaccgaa
      541 gtattcttga taatataact ttaaagaacg aagttacttc acaaaagata gaggaagttt
      601 gtaaagcagt tcaaatctat gatgaaatca tggctatgcc gatgaaattt aatactatca
      661 tctcagagat ggggtcaaat atttcaggtg gacaaaggca acggatagca ctggcacgtg
      721 cattaataaa taatcctagt attgtaattt tagatgaagc aactagtgca ttagacacta
      781 ttaatgagga aagaataaca aagtatatac aaagtcaggg ttgtactcaa ataattatag
      841 ctcatagatt gtcaacgatt aaggatgcgg atattatttt tgtaatgaaa ggtggtaaga
      901 ttgttgagtc aggaaatcat aagtacttaa tggatcttgg tggagagtac tacagcttat
      961 atacaaaaag gaaatgaggt gtaaagaaaa tgaagaaagt aaatgaatat gtaatttcaa
     1021 cagcagcctc actaggggtg atgattggaa tagtatttgc aattttttta gattttccag
     1081 ttgaatatgc tatttcttta ggtttgttga atggaatagt attgggttcg ctgatttttt
     1141 acaaaaacaa taagaattaa gcataatttt ttgctgtaaa ctaaggagta gagatggcta
     1201 tagttgaaat tataaatcta acaaaaagct ttaaagatat tgaagttatt cataacactt
     1261 cattttattt aaataaggga aaagtatatg gttttgttgg accaaatggg gctggaaaaa
     1321 ctacaattat caaaatgatt ctagggattt taaaaccaga ttctgggaaa ataactattt
     1381 ttaatcaaac cgtagaacag aattccgaaa atatattatc taggatagga ttagttttgg
     1441 gaccttcatt ttatggtcat cttgatgctt ataaaaattt gaagttaata gcaaatatga
     1501 aagggcttag tttagatact gaaagactta atgaatatct atcaatggta ggattaaaag
     1561 atgttaaaaa gaaaaaagtg aaaaattttt caatgggcat gaaacaacgt ctaagtatag
     1621 ctgcatcatt gttaggtagt ccagaaatat taatttggga tgaaccaatc aatggacttg
     1681 atccacaggg tgtaattgaa attagaagtt taatccgttt tctacaggag aaaaaaggta
     1741 ttacattttt aatatcaagt catattctta gtgaactgga taaagtgata tctgatatta
     1801 taattataaa ttatgggaaa gttga
//
LOCUS       DAVLCS010000090         1808 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLCS010000090 DAVLCS010000000
VERSION     DAVLCS010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1808
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.090"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(<1..201)
                     /locus_tag="VXC78_002076"
     CDS             complement(<1..201)
                     /locus_tag="VXC78_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584067.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENK"
     gene            complement(229..990)
                     /locus_tag="VXC78_002077"
     CDS             complement(229..990)
                     /locus_tag="VXC78_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV0584068.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFESIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            complement(990..1466)
                     /locus_tag="VXC78_002078"
     CDS             complement(990..1466)
                     /locus_tag="VXC78_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0584069.1"
                     /translation="MIGKNIKSLRKTHDLTQDDFSRIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
BASE COUNT          553 a          353 c          240 g          662 t
ORIGIN      
        1 cttattttca aaaaatatat catatagttc atcttcagta atttttctat atttcgttgc
       61 agtccaatta gaaaatagct tgtaatcata agaaacaggt gtatgcaaat gaattaaagt
      121 cttgtgaaag ctaccgaatt tctctttgga atttgttagt tcttgataaa cagactttat
      181 cttgttatta aaccctctca tttctattct cctaaaaata tcaattgttt atttttcaag
      241 taattcatta agtctctttt cccccacctg caacatctcc ttctctacct gactccactc
      301 cccaaagagt aactcttgaa gaacatctgc tgctgaagtt gtattttctt ttgaatcata
      361 tacacaactt ctatctcgtt ggtaaatttg aatgctttca aagatagcca gttcttccaa
      421 ttgtcgtgta ttatcaacta gatgatttac aatgaaatca tgatgttctt ttggagttgc
      481 gcgtgcttga tttggattga taatgtacag ttcttcataa cggataagag tacttagata
      541 cgacaattca ggctttgtcg caattaaggc caattgtact tcatatccct tatttttcaa
      601 gagttgtgct gttttctttg gaacatcaac tgttcgtaaa gttccctcga tcaaaagatt
      661 gtatctcaaa ctactcaatt ttgttactaa agactctacc atttttcctg caaaatcttt
      721 ggtatattct acactgtctt tgccatattc ttgctgcagt tctaaatagt gtggatgctg
      781 agaacgaaaa ctatcaccat ctatgataac aatatttcct tgaaattctt tctgtttaat
      841 acgatgaatt gtagtcttac cggcaccact ttgccctcca agcaaaatcg ctataggttg
      901 cttactggac ttttttcctc ttgtcagtga acgaagattc cttgctaaag catgtttgaa
      961 ttcactatca gtataatctt ggatttccat taagctacca tccgcttttc agatatctct
     1021 aacatacgtt caattccatc caaatagcca ctatatctct ctatttcatc aaaagtttct
     1081 actaaataga tattcgtatg aatcaagtca gatagatcat cactcattaa aatccaagga
     1141 ttagattcat catcaatgct aattccctga ctatcttgat aacgatagag tcgagataat
     1201 agattagcac ctctttcttt cacaatttca attttcaaag tcaattcata atcttcaaca
     1261 ggattgagca ttttatcttc tcctacaata tcgacataag atacattaaa cttctgacaa
     1321 atgatgtcta ttagttccgt agagactgaa ctagttccat tttcataccg gctcaagcta
     1381 tttcgagaaa ttcctacaat tcgggaaaag tcgtcttgtg ttaagtcatg tgttttacgt
     1441 aaggatttta tgttctttcc aatcatagca aactccttta tttttataaa tccattatag
     1501 cataaaaaag cataacgcac caaaaatggt gcgttatttc ttgtttttct atcctaaact
     1561 ttacttctat aaaagtcacc taaagagcta taaatattta ttcttgtatt aattttttcg
     1621 atgcgcaaac aatatctaca aatacatcta taacgattca ccttttagga tttttattgt
     1681 caaaattgcc tttatctaca aagacaaaat gcttataaaa tagcttgaaa ttaaggatta
     1741 tcaccttttt cgttgtagca acactccaca tgtgattatt aggctattag caaagcgtat
     1801 ccaatacc
//
LOCUS       DAVLCS010000091         1732 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLCS010000091 DAVLCS010000000
VERSION     DAVLCS010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.091"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            <1..330
                     /locus_tag="VXC78_002079"
     CDS             <1..330
                     /locus_tag="VXC78_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickase"
                     /protein_id="HEV0584070.1"
                     /translation="NNIETIGQLQTKIETLKSNSYRLNKKAKTIHKEMEDVEKKILYY
                     EIYKAKKEVYEEYQKKNIFTKEAFYNKHKKDIDQYKLVSGKLKKLLSDKEKLSPKKWN
                     EEKILLM"
     gene            656..829
                     /locus_tag="VXC78_002080"
     CDS             656..829
                     /locus_tag="VXC78_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584071.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            1015..1542
                     /locus_tag="VXC78_002081"
     CDS             1015..1542
                     /locus_tag="VXC78_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEV0584072.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            1669..>1732
                     /locus_tag="VXC78_002082"
     CDS             1669..>1732
                     /locus_tag="VXC78_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEV0584073.1"
                     /translation="MATNKRYYWIKLKEEFFTDKR"
BASE COUNT          919 a          218 c          261 g          334 t
ORIGIN      
        1 aacaacatag aaaccatagg tcagttacaa acaaaaatag aaactttaaa gtctaatagt
       61 tataggctaa ataaaaaagc aaagacaatc cataaagaaa tggaagatgt agaaaagaaa
      121 attctatact atgaaatcta caaagccaaa aaagaagttt atgaagaata tcaaaagaaa
      181 aatatattca caaaagaagc attttataac aaacataaga aagatataga ccaatataaa
      241 ttagtaagtg ggaaattaaa aaaactccta tcagataagg aaaaactaag tcctaaaaag
      301 tggaatgaag aaaaaattct tttaatgtaa aatcttgaag aaataaataa agaaaaagac
      361 aagataaaag atgaatacca ggaaattaat catataaaat attcagtaga ttttgtaaac
      421 aaagaacttg gtatagattt atccatagaa atagataagc taataaaaca gggagaaaaa
      481 ccaagtgtaa tagcacagat taaaaagttc caagaccaag ttaataaaga taatgaatac
      541 agagaaatga tgaaaaacaa gaaaatggat caagaaagat aagacctggt aaaaatatct
      601 tatccaagct ataatatgac caaacaacta aagtcagatc taggaggtaa tagagatgaa
      661 taaaaggcaa gagctaatag atgaactcat aaaagcaaat gaagatggaa catacaaaac
      721 ctataaaagc acagaagaaa taaaagcaat gaacaatgaa gaaatacaga ttatatattc
      781 caacatgaaa aactatctat cagacaaaag aacacacata aactattaaa ggtggaaagg
      841 tagtgtaagc tatttttaaa agtataaaag gtacaaagac ctaagaaata tataaaaaca
      901 tcaaaataaa gtattccacc accaagaaca ataaaataaa aacaagcaaa gggaagtata
      961 gaaaaattaa aacctatact tccctttttt aattcaaaca aaggagagaa aagcatgata
     1021 aacgaagaaa taagcaagga agcaggtcaa gcagcacaaa ccataatatc atacacaata
     1081 aaggcaacaa aagaatcaat caatttagaa aaagaaataa gaaaaaagat gaatgaaact
     1141 ttagaaaaag caaatggaaa cttaaaaagt cttatgggcg atgaaatgaa aataaaagat
     1201 ctctacaaga aaggacaact agaaaatata agcatagatc aaatcgacct caaagactta
     1261 aaaaaagaac taaacaaact tggagtaagt ttctcagtaa tgaaaaacaa agaaagcaaa
     1321 aactatgaaa tattcttcca agccaaagac ataaaagtaa tggaatatgc ctttaagcaa
     1381 gtcatagcca aggaaaataa aaaagaaaaa gaaagtatcc taaaacaaat aaagaaatac
     1441 aaagacctat ccaaaaacaa agataagaca aaagaaaaag gaaaaaggaa agtaaaagaa
     1501 aaagtaaaac caaacaaaaa agatatgacc agagaaatct aaagggagta acgaaaagtt
     1561 acacccttaa ataaccataa taacaagact tccgaaaaac agaagtccag aattccgaaa
     1621 atcggaaatc aagaatttcg attatcgaaa atcaagaaag gagcagatat ggcaacaaac
     1681 aaaagatact attggataaa attaaaagaa gaatttttca cagacaaaag ga
//
LOCUS       DAVLCS010000092         1682 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLCS010000092 DAVLCS010000000
VERSION     DAVLCS010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1682
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.092"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            84..491
                     /locus_tag="VXC78_002083"
     CDS             84..491
                     /locus_tag="VXC78_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0584074.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATPFKEVQKPLENFN
                     HIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            656..955
                     /locus_tag="VXC78_002084"
     CDS             656..955
                     /locus_tag="VXC78_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV0584075.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="VXC78_002085"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="VXC78_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0584076.1"
                     /translation="MMIQLSDLGQVHLVCGKTDMIQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWILYKRFENGKLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
BASE COUNT          570 a          330 c          297 g          485 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact cctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattgacta atactcttcg aaaataaaat tcaaaccaca tcagcgtcgc cttaccatac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttt attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcagctag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag gcctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataata aaacgcatag
     1021 tagcaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcggag
     1201 gaaaagtatt gtactatgat gattcaacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgataca aggaatcgat tcactggctt atctcgttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggatactat ataaacgctt tgagaacgga
     1441 aaactgactt ggcccagtac agaaaaggat gtcaaagctc tcgcacctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacccctact tctaaaacat tgttagaaat cgatttgact gtcctgatca atttgtcctg
     1621 ttcttgtttc attttactat agaacgattt gaaggcgttt atgatattta gctgtacgag
     1681 ag
//
LOCUS       DAVLCS010000093         1628 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLCS010000093 DAVLCS010000000
VERSION     DAVLCS010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1628
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.093"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            230..1183
                     /locus_tag="VXC78_002086"
     CDS             230..1183
                     /locus_tag="VXC78_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV0584077.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HTEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            complement(1203..1628)
                     /locus_tag="VXC78_002087"
                     /pseudo
     CDS             complement(1203..1628)
                     /locus_tag="VXC78_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          538 a          269 c          348 g          473 t
ORIGIN      
        1 accttagtca agaattagat gtttcactat gtttgagtaa gttgatgatt tcatttgata
       61 acaggtttga aactgttagg ctaggtggcc aaggctaatc atagccttgg tttagctgaa
      121 aaaacaggtt caagggttcc tgttgtcaaa tgaaatgtga tttaaggtat aagaaaacac
      181 ctctgtgcta tacttgttgt tcaccacaaa cacaaggaaa ggcacagaga tgcaagaaca
      241 ttatacccca aaagggaaac atttgacaat agataaccgt cgcttgattg agcggtggaa
      301 gaatgaaaat aagtccaatc gtgaaattgc aggcttgtta ggaaaggcgc ctcaaacgat
      361 tcatactgaa gtcaaaagag gtacaacttt acaacaagtg agaaaagggc tatacaaaaa
      421 ggtctattct gccgattacg cacaaactgt ttaccaattc aatcgaaaac ggtcggtgaa
      481 aaagttaatt ttaacaaagg aaatcagaga gaagatctta cactatcata agcaaaaatt
      541 ttcgcctgaa atgatggtta acaagaagca agtgaaagtt ggtatttcaa ccatctacta
      601 ctggtttcat aatggtcatt taggattgac gaaggccgac atgctttatc ccagaaaaag
      661 gaaaggtgtc aagaagcaag ctagtccgaa ctttaagccg gcaggtaaat ctatcgaaga
      721 acgtcctgac gttattaatc ttcgcttgga aaatggtcat tatgaaattg ataccgtcct
      781 actgactaag ataaaaaatt attgcctgtt agtcttaacc gaccggcgga gcagacacca
      841 aattataagg ttaattccaa ataaaactgc tgaatctgtc aatcaggcgc ttacgttact
      901 attaggggag catcgtattc tgtccattac tgcagataat ggttcggagt tcaaacgatt
      961 gtctgaggta tttcctgagg aacatatcta ctacgcacat gcttactctt catgggagag
     1021 aggttcaaat gaaaatcata atcgattaat tcggagatgg ttacctaaag gaaccaagaa
     1081 aacgactccg aaagaagtag cttttatcga aaattggatt aacaactacc ctaaaaaatg
     1141 cttggactac aagtcgccaa gtgaatttct tttgggtggc taacttcaac ttgaaatttg
     1201 ggttcaaagt ttcgaaaacc aaaggcattg cgtttgataa gtttgatgag attattggtc
     1261 gcttccaatt tggcgtttga atagggtagt tgaagggcgt tgacgatttt ctctttgttc
     1321 tttagaaagg ttttaaagac agtctgaaaa ataggatgaa cctgcttcag attgtcctca
     1381 atgagtccga aaaatttctc agggtctttg ttctgaaagt gaaaaagtaa gagttgatag
     1441 atctgatagt ggtgtttcaa gtcttctgaa tagcttaaaa tcttgtcaag aatttcttta
     1501 tttgttaagt gcatgcgaaa agtagggcga taaaaacgtt tatcgctgag tttacgacta
     1561 tcctgttgga tgagtttcca gtaacgcttg atagccttgt attcatgaga ttttcgttca
     1621 aactgatt
//
LOCUS       DAVLCS010000094         1512 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLCS010000094 DAVLCS010000000
VERSION     DAVLCS010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1512
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.094"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            <1..674
                     /locus_tag="VXC78_002088"
     CDS             <1..674
                     /locus_tag="VXC78_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV0584078.1"
                     /translation="KRIKRLRRISGGDTYTIIYLKLLLLSLKDEGKLYYDGVESDFIK
                     ELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTEIPNLIGSETAWAEKKRRYR
                     QNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYK
                     NLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYD
                     VGESL"
     gene            1358..>1512
                     /locus_tag="VXC78_002089"
     CDS             1358..>1512
                     /locus_tag="VXC78_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584079.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIET"
BASE COUNT          640 a          198 c          285 g          389 t
ORIGIN      
        1 acaaaaggat aaaaaggtta aggagaatat ctggaggaga tacctatacg ataatctacc
       61 taaaacttct actactaagc ctaaaagatg agggcaaact ctattatgac ggagtagaaa
      121 gtgattttat aaaagagtta gcactaacca tagatgaaac agacgatgat gtaatggtaa
      181 cagtaaatta tttaatcaat caaggcttat tagaagttgt aacagaaaat gatgaatact
      241 acctaactga aataccaaac ttaatcggat cagaaacagc ctgggcagag aaaaaaagaa
      301 gatacagaca aaataaacag aggacattgt ccttaatgag tccaacccat gtccgacaag
      361 agatagagat agagaaagat atagagatag ataaagagag agagggagag atagataaaa
      421 agtccacccc cattttttat ggagaattca aaaatgtaag gttaagcaaa gaagaatata
      481 aaaatctaaa agaaaaatta aactcacaca cagatataat gataaataaa ctatccagat
      541 acatggaaag cagtggtaag acctatcaaa accactatgt gacaatctta aaatggtatg
      601 aagaagataa agacaaacta agacagaaag gtttaaataa aaaaatgaat tatgatgtag
      661 gagaatcttt atagataaaa agaggtggaa aggcactatt aaagacttta agtttaaaaa
      721 ggtatcaaag tatgccagag ataaaaaaat ataaatatga cactttaaag gcgattagaa
      781 aattaaagaa atgctagaag acttttagat gacagttacc aagagggtct aattttcact
      841 gctacttatg cagtaggaat tggacctttt tatataagca aattctattt caaaattggt
      901 taccaagaaa gacttctttt cactgttaag tataagaggg taatttatag aattttgtta
      961 catcaagata aatattttct gatggtcaaa ttttaaaaag attaataact ttcgataaat
     1021 tttgaacctt aacaattgaa tagaccaaga caagacgtta attatttttg gagcgtaata
     1081 acctatccgt caagatcttt cggctgaata attcggcaaa aaaagttctg ctaagcaaaa
     1141 agaaagtgag cgataagtaa gagtttgaat atagggaggg ataccctatc cgctatgaag
     1201 aaaatgagga taatgatact tctaaggttg aagccggctc atccggaata gaggcggagg
     1261 tgagattcct atgttgctaa tccaaagcac ttgtcaatgt caaaaaactt aattaaacaa
     1321 ataattatta gatataaaac tttagaggag gtatatattg gacaatgact ggaatggatt
     1381 ggctgattta atagcaaatc tgattgcaaa atatgctggt gctttagatt tagataatct
     1441 acccgatcca acgccagcaa aaaatcaaga gatgaaaaat agttttgaca tggcaaaaac
     1501 acaaattgag ac
//
LOCUS       DAVLCS010000095         1509 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLCS010000095 DAVLCS010000000
VERSION     DAVLCS010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1509
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.095"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            19..1365
                     /gene="gdhA"
                     /locus_tag="VXC78_002090"
     CDS             19..1365
                     /gene="gdhA"
                     /locus_tag="VXC78_002090"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV0584080.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSNLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGVV"
BASE COUNT          450 a          303 c          323 g          433 t
ORIGIN      
        1 caataaaagg agaacgatat gacatctgct aaagaatata tccaaagcgt gtttgaaact
       61 gtaaaagctc gtaacgggca cgaggctgaa ttcctccaag ctgttgaaga atttttcaac
      121 actttggaac ctgtatttga aaaacaccct gagtatatcg aagaaaatat cttggcacgt
      181 attactgagc ctgagcgcgt gatttctttc cgtgttcctt gggttgaccg tgatggaaaa
      241 gttcaagtaa accgcggcta ccgtgttcaa ttcaactcag ctgttggacc atataaaggc
      301 ggacttcgtt tccacccaac tgtaaaccaa gggattttga aattcctcgg atttgaacaa
      361 atctttaaaa acgtcttgac tggacttcct atcggtggag gtaaaggtgg atcagacttc
      421 gatcctaaag gtaaaacaga tgctgaagtg atgcgcttct gccaaagctt catgactgaa
      481 ttgcaaaaac acattggacc atcacttgac gtacctgctg gtgatatcgg tgttggtgga
      541 cgtgagattg gttaccttta cggtcaatac aagcgtctta accaatttga tgctggtgtc
      601 ttgactggta aacctcttgg atttggtggt agcttgattc gtccagaagc aactggttac
      661 ggtttggttt actatactga agaaatgctc aaagctaacg gtaacagctt tgctggtaag
      721 aaagtggtta tttcaggttc tggtaacgtt gctcaatacg ctcttcaaaa agcaaccgaa
      781 cttggtgcaa cagttatctc tgtttctgac tcaaacggct atgttatcga tgaaaacggt
      841 atcgacttcg atcttttggt tgatgttaaa gaaaaacgtc gcgctcgttt gactgagtat
      901 gcagctgaga aagcaactgc tacttatcat gaaggttctg tatggactta cgctggaaac
      961 tatgacattg cgcttccatg tgctactcaa aacgaaatca acggtgaagc agctaaacgt
     1021 ttggttgctc aaggcgttat ctgtgtatct gaaggtgcca acatgccaag caaccttgat
     1081 gccatcaaag tttacaaaga aaatggtatc ttctacggac ctgccaaagc tgccaacgct
     1141 ggtggtgtag ccgtttcagc ccttgaaatg agccaaaaca gccttcgcct ctcatggact
     1201 cgtgaagaag ttgatggacg tctcaaagac atcatgacca acatctttaa cacagctaaa
     1261 acaacttcag aaacatatgg tcttgataaa gactaccttg caggagctaa cattgctgcc
     1321 tttgaaaatg tagcaaacgc tatgattgca caaggcgtgg tataaaaaaa aattacggaa
     1381 actgactacc cagacgggta gccagttttt tcaattccta aaatttaaga ttctaatacc
     1441 ctttatgcaa aaatatagaa ttctaccttt ttctttatat aggctaatgt ttttaatata
     1501 tttattgtc
//
LOCUS       DAVLCS010000096         1401 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLCS010000096 DAVLCS010000000
VERSION     DAVLCS010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1401
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.096"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            102..1280
                     /locus_tag="VXC78_002091"
     CDS             102..1280
                     /locus_tag="VXC78_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0584081.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT          522 a          253 c          204 g          422 t
ORIGIN      
        1 accagtaagt aatgaaaagc ttaaaaaaat taacatctac atttatccat agcaaaaaat
       61 cataggattt taagaatctg acaactagga agaaaactaa tatgacctta tctaagaaac
      121 aattacaact aagagctaaa atactggaaa cagtttacac attaggtccc atttcacgaa
      181 ttgaaatcgc tactaaaaca ggaataacac ctgcaacaac tagcagtatc acaaatgatc
      241 tgattaaaga aaatattctc ttagaacttg gtgaagacga acacgataca agcgtaggga
      301 gaaaaaaaat cctgctagac attcaagcta aacgatttta ctacattggt tgtgaactat
      361 ctgaaaaaca tttcactttt gctttaggag ataatctagg aaatatctta aaggaagaga
      421 aagaaattgt tactaaacag ttaatccaag aaaagggaaa tcaactcatt aaccagacac
      481 taaagcaatt cttaaataac tgctctgatt atgaaataga agcaattgga atcgcgctac
      541 ctggtcgcta tttagataat tataaaataa caacaaacaa tcctttatgg caacatatcg
      601 acttagaaat gattcaatcc cactttgata agcctttgtt tttctctaac aatgttaact
      661 gtatggctat aggtaaacgc ctatttagtc gccaacagaa tgaccctaat tttgcttatt
      721 ttcattttgc tagaggtatg cactgttctt atatctacga cggaaacatt tatgggaaag
      781 gaaatctaat gattggagaa atagggcata cagttgtttc atctgaggga gaagaatgta
      841 gctgcgggcg caagggatgc ttacaaactt ttgctggaga atcttggtta atcaaaaaat
      901 caaaaattct atatcatcaa tctccctatt ctctacttcc tagtttagtc aaaaatgccg
      961 atgatattga tatccaagtt attttaaccg cttatcaatt aggtgacact ggaataatca
     1021 cacttatcca tcaagcctta ctctatctta gtcaaaccat tttaaatatc agtatgatga
     1081 ttgactctca aaaaatctac ctacatagtc ctttactaac aaatcaacac atcatccaaa
     1141 aactatatag tgaaatgaac tacaaaccca aactgctcta taatcgccta cctgaagtca
     1201 ttattgaacc ttacaatgat tttacagccg cacactcagc tattgcactc tgtttgtatc
     1261 atacaattct acattcttaa ttttctatta catttaataa ataggctaaa aagagggagt
     1321 atatcataaa aagcgaataa acctgttttc tgaaaatcag aattctgttt tgttcgcttt
     1381 ctttatattt ggaattatac t
//
LOCUS       DAVLCS010000097         1399 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLCS010000097 DAVLCS010000000
VERSION     DAVLCS010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1399
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.097"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(<1..1098)
                     /locus_tag="VXC78_002092"
     CDS             complement(<1..1098)
                     /locus_tag="VXC78_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0584082.1"
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNKV
                     YIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGR
                     LILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILARS
                     MGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVVG
                     GVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSLI
                     YSVETEALNTISSIKISGLEDEIYENWSKYLK"
     gene            complement(1091..1372)
                     /locus_tag="VXC78_002093"
     CDS             complement(1091..1372)
                     /locus_tag="VXC78_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584083.1"
                     /translation="MRELNLCHGSVGTISCLDAILKDEENLLIKESIDFYFDNVVSQV
                     IKPELSTDLNTMNTFSFMLGVSGVVYEISRKQDDRLLNVLLLELRGHDD"
BASE COUNT          514 a          231 c          160 g          494 t
ORIGIN      
        1 ttttaaatac ttagaccagt tttcatatat ttcatcttct aatcccgata tttttattga
       61 agaaatagta tttaatgctt ctgtttctac tgagtaaatc aatgattgtt cttgtaattc
      121 tctattaacc gtatcataca ttatttttct agtactaaac agaaacaaaa aattgattaa
      181 actcaatata agagctataa ttgataatgt ttttgaacta agaaacatat atattacaac
      241 acttagaata gtcccgatat ctactactcc cccaacaact tggttagtaa atagctccct
      301 aaaaccacta agactagaaa ttctgtataa aatatctcct tttgccctga gttcaaaaaa
      361 actatatggt agtttaagca aatgcttaaa tgtaaaactt tcaatatctc tactaaaaaa
      421 tatattagaa aatagaattc ccatactcct agccaagata gaaataagat acaaacaaag
      481 tagagaaaat aaaattaaaa acgaggtttg aaaagaaaat gtattcccta atgcagaatt
      541 aataaacttt gaagtcatta ctggtacgga aagtattatt aagtaactta ttattgaaaa
      601 tagtaacgtc aaaatcaatc gaccttttac ctttgaaaaa ctagagaata ctcttatcca
      661 tggagaagga aactgcgact tcaaagattg ataattttcg ttaggaaatg atagcagtac
      721 tatattacta aaatgttttg aaaactcctt aaactcataa tttatatatc ctttagaagg
      781 atccattata tagaccttat tcttttttac tttgtaaata actacataat gttgattatc
      841 ccagaatgct attaatggta acggaagttc actaatttta tttacatctt taacttgata
      901 tgagccagta tcaaaatttc gtttattcaa taactgtttc aagtcaccta tactataacc
      961 atctctccct ttttctatat cacgtcttaa atctagtaat gtctctttgc ttttatagaa
     1021 atgtagtatg gacaagcagc aacataaacc acattctatt tgagacattt gctcaatatt
     1081 aggtactttt ctagtcatca tgtcctctta actccagtaa taaaacatta agtaatctat
     1141 catcttgttt tcgagatatt tcatagacaa ctccagatac tcctagcata aaagaaaatg
     1201 tattcatagt attcaaatcc gtacttaatt ctggtttgat gacctgagaa acgacattat
     1261 caaaataaaa atctatagat tcttttatta ataggttttc ttcatctttc aatattgcat
     1321 caagacaact gatagtacct acagaaccgt gacataaatt caattctctt attttttcta
     1381 cattagttaa tacattttt
//
LOCUS       DAVLCS010000098         1385 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLCS010000098 DAVLCS010000000
VERSION     DAVLCS010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1385
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.098"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            371..>1385
                     /locus_tag="VXC78_002094"
     CDS             371..>1385
                     /locus_tag="VXC78_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEV0584084.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIYDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVIDNPKLFNLTNYLLTYSEIQKEKSKYLKGYAKT
                     NKEK"
BASE COUNT          647 a          180 c          235 g          323 t
ORIGIN      
        1 tagaagaaag aatagatgat aatgtagaaa aatcatctaa agatgaaata acataattgt
       61 cccttggtta caagggcgca attatacacc ctaaagggtg cttgcgtcct gcggagtcaa
      121 acccttgcag ggagcaataa ccattcgctt tttaaaagtc aagggtaaat aaactcgcta
      181 aagctcgccc ttgacttttt aaaatttgaa atgaaagtaa caattaagcc gacatactga
      241 aacaacaaaa attaattcag tagtcggctt ttttaatttt atcatttcaa aacgctcatt
      301 cacaaagagg atataaaaaa actattaagc ctccacctaa aacaacaaag aaagaaagga
      361 agtgataaaa atggcagaca gttttcattt ttcagtaaac ataatatcaa gaggaaaagg
      421 caaaagtgca gtagcaagtg cagcatatat aagtggagaa aaaataaaaa atgaatggga
      481 cggagtaacc catgactaca caagaaaaga aaaaatatta gtaaaaaata taatattgcc
      541 tgatcatata ccaaaagaat ttaatgatag gtctacctta tggaataaag tagaaatggc
      601 agaaaaaaat tctaatgcac aactagcaag acaattcata ataggactac caaaagagtt
      661 atctttaagt gaaaataaaa acctggttga aagatatata aaagaaaatt taacatcaca
      721 aggaatgata gtagattatg caatttatga tgagagtcaa gataaaaatg gaaatatcca
      781 ttgtcatata atgaccataa tgcgaccaat aaacgaaaaa ggagagttct tagccaagtc
      841 aaaaaaagaa tatatcctag atgaaaaagg agaaaaagta ttaaacaaaa atggaaaacc
      901 aaagacaaga aaagtagaac taacaacctg gaacgataca ggcaatgtag aaaaatggag
      961 agaaaatttt tcagatcttt gtaacaaata tttagaaaga gcaggagcag aaaaaagagt
     1021 agaccatagg agttttaaaa gacaaaattc agattatcta ccgacaatcc atttaggatc
     1081 agcagcaagt gcaatggaaa gaaagggaat agaaactgac aagggaaact ataatagaga
     1141 aataagaaaa tataatcaac ttgtaaaaac aataaaagaa gagataaaaa cattaaaggg
     1201 ttggatagga aatttattag ataacttatc tactgcttat gaaaaattta aggatatcga
     1261 aagagataag gtaatagaca accctaaact ttttaatcta acaaattatc tattaactta
     1321 ttcagaaatt caaaaagaaa aaagtaaata tctaaaagga tatgcaaaaa ctaataaaga
     1381 aaaat
//
LOCUS       DAVLCS010000099         1379 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLCS010000099 DAVLCS010000000
VERSION     DAVLCS010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.099"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            4..>1379
                     /locus_tag="VXC78_002095"
     CDS             4..>1379
                     /locus_tag="VXC78_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEV0584085.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQILNSVTGDEKKII
                     EFFRDSIL"
BASE COUNT          523 a          162 c          246 g          448 t
ORIGIN      
        1 aatatggaag aaaattataa tttatctata actcaaataa agaattctat taaagaaaat
       61 tccttagttt tgtttgttgg tgcaggaata tcagctaatt ctaatctacc aacttgggga
      121 gaattgattc aatcattaaa aaaagaattg aacataccag aagaaagaac agatagtcca
      181 ctgagaattg ctcagtatta ttatgatact tttgggaaaa atcagtacac aaagaagata
      241 gaagaaattt tctttaagaa gggattgagt aaaccaaatg agttacataa attaatagaa
      301 aaaattgcac caaaacatat tattacgaca aactatgatt cacttctgga gagtcaattt
      361 gaaagtggct tgttaaagta caatgtagtc gctgaggata aagacatccc ttatacgagt
      421 tcggaaagat acttgattaa aatgcatggt gacttcagta agaaaaatat tgttttgaaa
      481 gaagatgatt atttagacta tcatttgaac ttcccaatga tttctacttt aatccagtca
      541 ttgataatga atcatactct attgtttgtg gggtattctc taagtgattc gacttttaat
      601 tcaattttta gaatgattca aaatacattt aaattggatg ctaaaaatgc ttatttttat
      661 actcccgagg aaccgtctat gatcattcga gagtattata agaagcaagg aattttcatt
      721 atctctaatg aagagaatct aggtcaggag acatcagaaa aacagaacaa attgtattgc
      781 aggacaaaag attttttaga ggttctatca gaaaaccgaa gtcaagatgt aaataatgct
      841 gatgatttat ggaatcaact ggctttttta gatagactta gttttattga tgcgaaagat
      901 ttttctagat attctgattt aaagaaaagg gctttaaact gggatgatga gtattgctgg
      961 tttggaaatg atcaattaag atttgaaatt gatggtcatg aagaattacg aattatggta
     1021 tctaaaaaat ctttattaaa tcgctttcta gatatggaga ttggtgagcc tagggattta
     1081 aaggggaatc gattcttaag taaggctttt aagttgtatg aagaaaaaca atattcttta
     1141 gcaaaagcaa aatttagaga actagctaat atagcatttc gtcagaaaga ctattttaat
     1201 ttcttagttt gtgaatttaa ttttcagcaa attcaaataa ttgatagata cgaaaaaaca
     1261 cctagttatg cagagccact ttatgatgga gaattaagtg aattaacaga acaaattctt
     1321 aactcggtta caggagatga gaaaaagatt atagaatttt ttagagattc aatccttaa
//
LOCUS       DAVLCS010000100         1205 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLCS010000100 DAVLCS010000000
VERSION     DAVLCS010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1205
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.100"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            240..839
                     /locus_tag="VXC78_002096"
     CDS             240..839
                     /locus_tag="VXC78_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584086.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEGTGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            982..1152
                     /locus_tag="VXC78_002097"
                     /pseudo
     CDS             982..1152
                     /locus_tag="VXC78_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT          431 a          178 c          246 g          350 t
ORIGIN      
        1 cgttaatatt tggagaagag gatggccatc ttctccattt ttatgtgcag agttatagtg
       61 acttgatgct gggaaagtac actgtgactg ctaatactca atgaaaatca aagtgcaaac
      121 taggaagcta gccgcaggct gtacttgagt acgtcaaggt gaagctgacg tggtttgaat
      181 ttgattttcg aagagtataa aacattccta gaagttactt tgatttccct aatctattta
      241 tgcaaatttt atgttatttt actataacag ttgttgctaa gccaaataat agtggggaag
      301 ttcatttaga cgtaagcatt gaagataatc agggaggtag tgggcataat ttcagttctg
      361 tttcaagtag ctcacaaaca gctaaatatg aaggaactgg ttataataac aattcatcat
      421 tatatataac gattgataaa acgtctgatg caacagctct tttgaaatta aagttgaata
      481 atgttgataa tcaacctgct actgaagttc ctagttcagg aattactgta aaattaaatg
      541 ctaaagataa tgctggaaac tggacaagtg cttcgaataa aaaagaagta acagtaaaaa
      601 ttgtttctgc taaaccgaca tatccagaca aaatcttagt gaaaaatcct gataatataa
      661 aagatacaga aaaaaatgcc attattgaaa aattgaaaga ggcaaataaa aatcatccag
      721 caggagctcc aacctttgct aaaggtgaag gagagcatgc aaatgatatt gtagcaactt
      781 attcagatgg tacaacttat tatgtaccgt taaatgatgt gacaaaatat gcgaggtagt
      841 ggctgtacca ctcacttatt cacctccccg tgatttgtag tagtgatagg ctttctcact
      901 attattataa aacaaaataa agatcacaac actttttcat tctgtgttgt gccttgagtg
      961 aaacgaaagg aatgaattat aaatatgaaa agtatagtca ctagcataga tgagcgcttg
     1021 cgtactcgcc tacgagtgat tatctggaag caatggaaga agaaatcgag acgattatgg
     1081 ggattgctta agttaggggt tcctaaatgg atagcagata aggtatctgg ctggggcgac
     1141 cactatcaat tatattaaaa tgaaataaga ataggacgaa tcgatcaggg aagtcaaatc
     1201 gattt
//
LOCUS       DAVLCS010000101          932 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLCS010000101 DAVLCS010000000
VERSION     DAVLCS010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..932
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.101"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            101..289
                     /locus_tag="VXC78_002098"
                     /pseudo
     CDS             101..289
                     /locus_tag="VXC78_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828969.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            326..>932
                     /locus_tag="VXC78_002099"
     CDS             326..>932
                     /locus_tag="VXC78_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HEV0584087.1"
                     /translation="MDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLGAGALGCYISLSL
                     SMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSQKIHKYNSDVQVVPISI
                     KVSSVEELENIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLII
                     DNIYIPTIGSCFACRNINKDINKYTLSDKTKWPTTPEMPAIL"
BASE COUNT          330 a          111 c          174 g          317 t
ORIGIN      
        1 ctattacaat ttttgacacc taatattatt gttcgtagta taggaggggt agttgtttct
       61 atactgcttt ctatattata tatgagagga aggacgaaat atgttctacg taaatagtta
      121 tgtttttgct tataaaaaag aaggtataat gtatttgcgt ggtcggagta tgcgggaaat
      181 agctatagaa cctcaaattt cgcaagaatt tatcaacgat ctatttaata gttgtaagga
      241 actattagag atagaagaag tattaggtag taaactaaca tttgaactat taaatgaaca
      301 aattttaatt tcggatgaga tagatattga tagtagatat tctagaacta aaggttacta
      361 ttcgttattt tataatgaag agtataataa aatacagaat aaaacagtat tagtattagg
      421 agccggagcc ttaggatgtt atatatctct aagtctaagt atgtatggag tgaggaaact
      481 tattgtcgct gattacgata taatagaacc atcaaattta aataggcaaa ttctttatac
      541 agagtcggat gttggtaagg agaagattaa tgttctttct caaaaaatac acaagtataa
      601 ttcagatgtt caggtagtac ctatttctat taaagtttct tcagtagaag aattagaaaa
      661 cattgttgcg gaatatggga gtatagattt tatcgttaaa gcaattgata cgcccattga
      721 tattataaaa attgtcaatc aatttgctgt atcgcataag atatcctaca tatcaggagg
      781 gtttaatgga tgctatctta ttattgataa tatatatatc cctaccatcg gttcttgctt
      841 tgcttgtcgg aatataaaca aagatataaa taagtacact ttatctgata agacaaagtg
      901 gccgactaca ccagagatgc ctgctatttt gg
//
LOCUS       DAVLCS010000102          809 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLCS010000102 DAVLCS010000000
VERSION     DAVLCS010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.102"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            complement(43..189)
                     /locus_tag="VXC78_002100"
     CDS             complement(43..189)
                     /locus_tag="VXC78_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0584088.1"
                     /translation="MKTKEQTRKLAAGCSKHCFEVVDRTDEVSNHTHGKATLTWFEEI
                     FKEY"
     gene            347..565
                     /locus_tag="VXC78_002101"
     CDS             347..565
                     /locus_tag="VXC78_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV0584089.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
BASE COUNT          260 a          118 c          150 g          281 t
ORIGIN      
        1 cgaaatctag tggaatgaat ctggaatagt ccatcgagct ttctaatact ctttgaaaat
       61 ctcttcaaac cacgtcaacg tcgccttgcc gtgcgtatgg ttactgactt cgtcagttct
      121 atccacaacc tcaaaacagt gttttgagca acctgcggct agtttcctag tttgctcttt
      181 ggttttcatt gagtataaca cattgttaga agttggttta aatttcctaa tcagtttgtt
      241 cacatttacc ttcgatatat tatatcccat agttaaggtt ggtcatacag atgattatag
      301 ccatggagcc gtaaaactta gtgtttcttt agttgacaaa gatgccatga aaaaaatatc
      361 tgtaactgta ataggatatt ttgaaataaa tatagatgaa aatatcaccg atattctata
      421 cgtaaatggt actgctattc tttatcctta tttacgttct attgtttcaa tagtttcggc
      481 aattgatagc agtgaagcaa tgttgctacc taccattaat gttttagagt tactagataa
      541 atctcaacct tttgaagaag aataatttat tagctcacta aattgagggt aaggaaaagt
      601 aaaagcagta agaaaaatgt cttgcattat acagcaactt tttgggaatg agtagatgga
      661 ttgaataaaa tttgattaag agtggatgat ttatctgtag attattattg gacagttagt
      721 cttgaagtag tctaagaatt aggttataat cagtagaagc cttgctaata atgaggaggt
      781 tagtttatgt atagtagact gaatctaaa
//
LOCUS       DAVLCS010000103          735 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLCS010000103 DAVLCS010000000
VERSION     DAVLCS010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.104"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            81..263
                     /locus_tag="VXC78_002102"
     CDS             81..263
                     /locus_tag="VXC78_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0584090.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLCFNEKFGTENT"
     gene            273..638
                     /locus_tag="VXC78_002103"
     CDS             273..638
                     /locus_tag="VXC78_002103"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0584091.1"
                     /translation="MPNSESTKPKTFEIDCLVGKKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            635..>735
                     /locus_tag="VXC78_002104"
     CDS             635..>735
                     /locus_tag="VXC78_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0584092.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKT"
BASE COUNT          307 a           94 c          121 g          213 t
ORIGIN      
        1 attagaaaga aaaaatcgaa aaattagcta agaaatattc tgataactta aacatcaaag
       61 ttcaagagag agttcgtgaa atggcaaatg ataataagag ccattatttg atatacagag
      121 ttttaggtat ttcatttgaa gaaggagaaa atatcgattt gtatcaaaat aaaggtcgtt
      181 ttttatacaa atatgctggt tcatttttag aagaagctgc agtactatgc tttaacgaaa
      241 aatttggtac agaaaatact taaaaagtta acattcctaa ttctgaaagt acaaaaccta
      301 agacttttga aattgattgt ttagtcggaa aaaaacacgc atacgaaata aaatggtggg
      361 atgcaactac agatggagac catataacta aagaacacac tagaataaaa gttattcata
      421 acaaaggata tataccaatt cggttaatgt tctactatcc aaatagaact caagctataa
      481 aaattcagca aactttagaa acattgtata acggtattgg agggaaatat tattatggag
      541 attctgcctg ggaacattta agagcagtga ccggtattga tttacttagt attctaacag
      601 atattgcaaa taaaaaaaca ggggtaaaat caaaatgaca gtattaaaag gagataactt
      661 agaaatatta aaaactattg aatcctcaag tattgattta atctatatgg accctccttt
      721 ctttacacag aaaac
//
LOCUS       DAVLCS010000104          614 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLCS010000104 DAVLCS010000000
VERSION     DAVLCS010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.105"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            1..614
                     /locus_tag="VXC78_002105"
                     /pseudo
     CDS             1..614
                     /locus_tag="VXC78_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          196 a          116 c          112 g          190 t
ORIGIN      
        1 gcttatttga ctgaaatagc ttctgaattt ggctgtcatc taactaccat ccactatgcg
       61 ctcaaagcta tgggttacac tcgaaaaaaa gaaccacacc tactatgaac aagacccaga
      121 aaaagtagcc ttatttctta agaattttaa tagtttaaag cacctagcac ctgtttagat
      181 tgacgaaaca ggattcgata cttattttta tcgagaatat ggtcgctcat taaaaggtca
      241 gttaataaga ggcaaagtat ctggaagaag atatcagaga atttctttgg ttgcaggtct
      301 aacaaatggt gagttaatcg ctccaatgac ttacgaagag acgatgacga gcgacttttt
      361 tgaagcttgg tttcagaagt ttctcttacc aacattaacc acaccatcgg ttattattat
      421 ggataatgca agattccata gaatgggtaa gttagaactc ttgtgtgaag agtttgggta
      481 taacttttta cctcttcctc cctactcacc tgagtacaat cctattgaga aaacatgggc
      541 tcatatcaaa aagcacctca aaaaggtatt accaagttgc aatacctttt atgaggctct
      601 tttgtcttgt tctt
//
LOCUS       DAVLCS010000105          578 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLCS010000105 DAVLCS010000000
VERSION     DAVLCS010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..578
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.106"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            <1..>578
                     /locus_tag="VXC78_002106"
     CDS             <1..>578
                     /locus_tag="VXC78_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0584093.1"
                     /translation="SHVKNKIDNIESQVYTKTNFINQKDKKGSIEDSVLNIVFVTTRT
                     KYCSQILQLLLKYFDKNPNKISEVYSILEANYGLVTEREYIDYTLAENTISELANLDL
                     TKSYNQELIVTILKQFLKIEIERTEAHEEKFTFGRYKVPDSEKLKQYHRSILKLLANL
                     YNIGSCETRFYIEKMLYDYRRKILTYSESHRN"
BASE COUNT          227 a           66 c           96 g          189 t
ORIGIN      
        1 tttcacacgt taaaaataaa attgataata tagagtctca ggtttataca aagactaatt
       61 ttattaatca gaaggataaa aagggatcta ttgaggattc agttttaaat attgtatttg
      121 taactacacg gacaaaatat tgtagtcaaa ttctccaatt attgttaaag tactttgata
      181 aaaatcctaa taaaatttct gaggtttata gtattcttga agcaaactac gggttggtta
      241 cagaaagaga atatattgat tataccttag ctgaaaatac catttctgaa cttgctaatc
      301 ttgatttgac gaaaagttat aaccaagaat taatcgtgac aattttgaag cagtttctta
      361 aaattgaaat cgaaagaaca gaggctcatg aagagaaatt tacttttggg cgctataaag
      421 tcccggatag tgaaaaatta aaacagtatc atagaagtat actaaaactt ttagcgaatt
      481 tgtataatat agggagttgt gaaactagat tttatattga gaaaatgcta tatgattaca
      541 gaagaaaaat tttgacctat tcagaaagtc atcgtaat
//
LOCUS       DAVLCS010000106          568 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040310
            SAMN33606965-rid17937903.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLCS010000106 DAVLCS010000000
VERSION     DAVLCS010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606965
            Sequence Read Archive: SRR23726086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721963.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721963.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:20:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,107
            CDSs (total)                      :: 2,061
            Genes (coding)                    :: 1,928
            CDSs (with protein)               :: 1,928
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 59 of 133
            Pseudo Genes (incomplete)         :: 63 of 133
            Pseudo Genes (internal stop)      :: 38 of 133
            Pseudo Genes (multiple problems)  :: 22 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606965-rid17937903.denovo.107"
                     /strain="AUSMDU00040310"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST416"
     gene            <1..>568
                     /locus_tag="VXC78_002107"
     CDS             <1..>568
                     /locus_tag="VXC78_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0584094.1"
                     /translation="PIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDI
                     TSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKG
                     AEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAP
                     KGYTLEDLLATVKYYVEHPNERPHSDNGF"
BASE COUNT          183 a          119 c          126 g          140 t
ORIGIN      
        1 ccgattcgtc atccagaacg tttaggaaaa ccaaatgcgc aaattaccta cactgatgat
       61 gagattcaag tagccaagtt ggcaggcaag tacacaacag aagacggtta tatctttgat
      121 cctcgtgata taaccagtga tgagggggat gcctatgtaa ctccacatat gacccatagc
      181 cactggatta aaaaagatag tttgtctgaa gctgagagag cggcagccca ggcttatgct
      241 aaagagaaag gtttgacccc tccttcgaca gaccatcagg attcaggaaa tactgaggca
      301 aaaggagcag aagctatcta caaccgcgtg aaagcagcta agaaggtgcc acttgatcgt
      361 atgccttaca atcttcaata tactgtagaa gtcaaaaacg gtagtttaat catacctcat
      421 tatgaccatt accataacat caaatttgag tggtttgacg aaggccttta tgaggcacct
      481 aaggggtata ctcttgagga tcttttggcg actgtcaagt actatgtcga acatccaaac
      541 gaacgtccgc attcagataa tggttttg
//
